The understanding of pig genetics and genomics has advanced significantly in recent years, creating fresh insights into biological processes. This comprehensive reference work discusses pig genetics and its integration with livestock management and production technology to improve performance. Fully updated throughout to reflect advances in the subject, this new edition also includes new information on genetic aspects of domestication, colour variation, genomics and pig breeds, with contributions from international experts active in the field.

Why do males and females frequently differ so markedly in body size and morphology?
Sex, Size, and Gender Roles is the first book to investigate the genetic, developmental, and physiological basis of sexual size dimorphism found within and among the major taxonomic groups of animals. Carefully edited by a team of world-renowned specialists in the field to ensure a coherence of style and approach between chapters, it presents a compendium of studies into the evolution, adaptive significance, and developmental basis of gender differences in body size and morphology. Adaptive hypotheses allude to gender-specific reproductive roles and associated differences in trophic ecologies, life history strategies, and sexual selection. This "adaptationist" approach is balanced by more mechanistic studies of the genetic, developmental and physiological basis of sexual size dimorphism to provide a comprehensive and authoritative overview of the subject. Throughout the volume the emphasis is on sexual dimorphism in overall size; however, the scope of enquiry encompasses gender differences in body shape, the size and structure of secondary sexual characteristics, patterns of growth (ontogeny), and patterns of gene regulation.
This advanced, research level text is suitable for graduate level students and researchers in the fields of evolutionary biology, behavioral ecology, physiology, developmental biology, and genetics. It will also be of relevance and use to non-biologists from fields such as anthropology and gender studies.
NEW IN PAPERBACK

This compendium provides a concise and up-to-date assessment of critical recent issues related to erythroid biology. Developmental, epigenetic, methodological, biochemical, and clinical aspects are integrated to provide a powerful overview of their interrelationships and importance to the generation of the red cell. The excitement generated by these novel observations and the anticipation of future directions in studies of the red cell is a highlight of this volume.
*The first comprehensive volume covering the breadth of the topic
*The latest advancements that lead to novel directions in the study of red cells
*An informative discussion of red cells as they relate to the essential oxygen-carrying component of the body

The eye is a complex sensory organ, which enables visual perception of the world. Thus the eye has several tissues that do different tasks. One of the most basic aspects of eye function is the sensitivity of cells to light and its transduction though the optic nerve to the brain. Different organisms use different ways to achieve these tasks. In this sense, eye function becomes a very important evolutionary aspect as well. This book presents the different animal models that are commonly used for eye research and their uniqueness in evaluating different aspects of eye development, evolution, physiology and disease.
* Presents information on the major animal models used in eye research including invertebrates and vertebrates
* Provides researchers with information needed to choose between model organisms
* Includes an introductory chapter on the different types of eyes, stressing possible common molecular machinery

Pursuing the questions of how we learn and how memory is made, Edward Kosower introduces a novel and rich approach to connecting molecular properties with the biological properties that enable us to write and read, to create culture and ethics, and to think. Here he examines what happens within a single cell in reaction to external stimuli, and shows the parallels between single cell and multicellular responses. To address the problem of "learning," Kosower explains the molecular mechanisms of responses to input from taste, olfactory, and visual receptors. He then shows how these and other processes serve as the basis for memory. This study covers such signals for the molecular process of learning as pheromones (the molecular signals mediating behavior), light (activates the G-protein receptor, rhodopsin), and acetylcholine (opens the nicotinic acetylcholine receptor). Kosower's discussion of the structure and function of these complex molecules has direct implications for such areas as molecular neurobiology, bioorganic chemistry, and drug design, in elucidating approaches to the structure of drug targets. Originally published in 1991. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

There is now enough basic work to sketch out the principal systems at all levels of the brain, from prefrontal cortex to lower brainstem, which are orchestrated to provide control of food selection, preference and consumption. At the same time, the complex interplay between central systems and signals generated from peripheral systems include the gut, liver and fat stores, as well as the interactions with the neuroendocrine system can be described in some detail. A continuing theme throughout the book is that the functional analysis of appetite and food intake cannot be limited to a single focus, e.g. hypothalamic neuropeptides and their interactions, but must be based on a fully integrated view of the several contributing systems.
Appetite and Body Weight: Integrative Systems and the Development of Anti-Obesity Drugs provides an expert guide to the neural, neurochemical, autonomic and endocrine interrelations which underpin appetite and the controls of food intake and body weight. The book covers many of the neurochemical entities that are currently under investigation, including: neuropeptides, leptin, insulin, monoamines and endogenous cannabinoids in relation to appetite and body-weight control. In addition to the neuroscience analysis, there are also chapters that provide an expert guide to some of the key psychological concepts that the researchers believe are essential in trying to understand the phenomena under investigation. The volume will also serve as an authoritative guide to the current emphasis on the development of novel, efficacious anti-obesity medication.
* Provides an integrative view of the many systems involved in appetite and how they interact to effectfood intake (i.e. the brain, endocrine, gut, liver etc.)
* Considers psychological aspects such as incentive, preference, liking and palatability, and sets these concepts in their behavioural, pharmacological and neural contexts
* Examines the development of novel anti-obesity drugs, drawing on experience of pharmacological development work, pre-clinical tests for anti-obesity efficacy, and clinical trials of candidate anti-obesity compounds

In an important new contribution to the literature of chaos, two distinguished researchers in the field of physiology probe central theoretical questions about physiological rhythms. Topics discussed include: How are rhythms generated? How do they start and stop? What are the effects of perturbation of the rhythms? How are oscillations organized in space? Leon Glass and Michael Mackey address an audience of biological scientists, physicians, physical scientists, and mathematicians, but the work assumes no knowledge of advanced mathematics.

Variation of rhythms outside normal limits, or appearance of new rhythms where none existed previously, are associated with disease. One of the most interesting features of the book is that it makes a start at explaining "dynamical diseases" that are not the result of infection by pathogens but that stem from abnormalities in the timing of essential functions. From Clocks to Chaos provides a firm foundation for understanding dynamic processes in physiology.

"Glimpses of Creatures in Their Physical Worlds" offers an eye-opening look into how the characteristics of the physical world drive the designs of animals and plants. These characteristics impose limits but also create remarkable and subtle opportunities for the functional biology of organisms. In particular, Steven Vogel examines the size and scale, and trade-offs among different physical processes. He pays attention to how the forms and activities of animals and plants reflect the materials available to nature, and he explores the unique constraints and possibilities provided by fluid flow, structural design, and environmental forces.

Each chapter of the book investigates a facet of the physical world, including the drag on small projectiles; the importance of diffusion and convection; the size-dependence of acceleration; the storage, conduction, and dissipation of heat; the relationship among pressure, flow, and choice in biological pumps; and how elongate structures tune their relative twistiness and bendiness. Vogel considers design-determining factors all too commonly ignored, and builds a bridge between the world described by physics books and the reality experienced by all creatures. "Glimpses of Creatures in Their Physical Worlds" contains a wealth of accessible information related to functional biology, and requires little more than a basic background in secondary-school science and mathematics.

Drawing examples from creatures of land, air, and water, the book demonstrates the many uses of biological diversity and how physical forces impact biological organisms.

This is the first book to summarize the methods, conceptual issues and results of studies using the interpretation of feather growth rates as an index to nutritional condition in birds. The author has coined the term ptilochronology (literally. 'the study of feather time') to describe this technique, which relies on the fat that as a feather grows it produces visible growth bars. Both the technique and its conceptual foundations have been applied worldwide to numerous studies of avian evolution, ecology, and conservation biology. the author reviews this work, chronicles the various criticisms that have been amde, and describes how these have influenced the development of ptilochronology. He goes on to suggest experimental methodologies and analytical techniques to safeguard against invalid results. a final chapter summarises this new technique's contribution to avian biology, and suggests potential applications and a future research agenda. an appendix details specific measurements and describes the methodology associated with ptilochronology.
Ptilochronology provides a practical resource as well as a conceptual understanding of how this technique can be used to address important questions in avian biology. It will be of relevance and use to professional avian biologists and ornithologists as well as to graduate students of avian behavioural ecology, evolution and conservation.

Biology of Stress in Fish: Fish Physiology provides a general understanding on the topic of stress biology, including most of the recent advances in the field. The book starts with a general discussion of stress, providing answers to issues such as its definition, the nature of the physiological stress response, and the factors that affect the stress response. It also considers the biotic and abiotic factors that cause variation in the stress response, how the stress response is generated and controlled, its effect on physiological and organismic function and performance, and applied assessment of stress, animal welfare, and stress as related to model species.

Professor Wever studies the structure of the ear and its functioning as a receptor of sounds in all amphibian species (139) for which living representatives could be obtained Originally published in 1985. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

This Fifteenth Symposium of the Society for the Study of Development and Growth is divided into three parts. In the first group of chapters T. T. Puck discusses the methods of deriving cultures from single animal cells; R. Dulbecco, problems of virus reproduction; and R. M. Klein, the current status of cultivating plant tissues. D. M. Prescott then examines the rhythmic growth and division of Amoebae; C. S. Pittendrigh and V. G. Bruce contribute a review of their analysis of internal clocks in animals; and E. Bunning writes on diurnal rhythms in vascular plants. Finally H. Gaffron and B. L. Strehler discuss the origin, significance and mechanics of photosynthesis while H. F. Blum and H. Shapley take up other aspects of biochemical evolution. Originally published in 1957. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Paxinos and Franklin's The Mouse Brain in Stereotaxic Coordinates, Fifth Edition, emulates in design and accuracy Paxinos and Watson's The Rat Brain in Stereotaxic Coordinates, the most cited publication in neuroscience.

Cephalopods are fast-moving, voracious predators, and can change colour with breath-taking rapidity. They range from the giant squid, the world's largest marine invertebrate, to species of only 2 cm in length. Inhabitants of most seas of the world, they are found from the surface to great depths. Most cephalopods have short lives yet their efficiency in capturing and consuming prey ensures rapid growth. These animals possess highly-developed nervous systems, large brains, elaborate senses, complex behaviour and are capable of learning. Many of these features are described and illustrated with line drawings and photomicrographs.

This book covers the wide area of developmental physiology of the intestine: changes in the structure and function of the gut during perinatal period and weaning in mammals, role of nutrients (in particular colostrum and milk), neuroendocrine function of the intestine, intestinal motility, secretion and absorption and their neurohormonal regulation, novel knowledge on gut metabolism, and the structural and functional expression of circadian variability in the gut. It also contains unique information on the luminal action of gut regulatory peptides, and the role of the electric current generated by intestinal smooth muscle on gastrointestinal microbial growth.

Advances in Insect Physiology is committed to publishing eclectic volumes containing comprehensive and in-depth reviews on all aspects of insect physiology. First published in 1963, these volumes are an essential reference source for invertebrate physiologists, neurobiologists, entomologists, zoologists, and insect biochemists. This latest volume now has a new four-color laminated cover.
In 1999, the Institute for Scientific Information released figures showing that Advances in Insect Physiology has an Impct Factor of 4.5, placing it second in the highly competitive category of Entomology.
Key Features
*NEW (and improved) cover!!!!
* Comprehensive reviews, written by experts
Key Features of the Series:
*first vol published in 1963.
* Adv Insect Physio ranked 2nd in Entomolgy list (acc to ISI data released in 1999) with an Impact factor of 4.5

This second volume in the Natural History of the Crustacea series examines how crustaceans-the different body shapes and adaptations of which are described in volume 1-make a living in the wide range of environments they inhabit, and how they exploit food sources. The contributions in the volume give synthetic overviews of particular lifestyles and feeding mechanisms, and offer a fresh look at crustacean life styles through the technological tools that have been applied to recent crustacean research. These include SEM (scanning electron microscope) techniques, micro-optics, and long-term video recordings that have been used for a variety of behavioral studies. The audience will include not only crustacean biologists but evolutionary ecologists who want to understand the diversification of particular life styles, ecologists who follow the succession of communities, biogeochemists who estimate the role of crustaceans in geochemical fluxes, and biologists with a general interest in crustaceans.

Molecular mechanisms in visual transduction is presently one of the most intensely studied areas in the field of signal transduction research in biological cells. Because the sense of vision plays a primary role in animal biology, and thus has been subject to long evolutionary development, the molecular and cellular mechanisms underlying vision have a high degree of sensitivity and versatility. The aims of visual transduction research are first
to determine which molecules participate, and then to understand how they act in concert to produce the exquisite electrical responses of the photoreceptor cells.
Since the 1940s 1] we have known that rod vision begins with the capture of a quantum of energy, a photon, by a visual pigment molecule, rhodopsin. As the function of photon absorption is to convert the visual pigment molecule into a G-protein activating state, the structural details of the visual pigments must be
explained from the perspective of their role in activating their specific G-proteins. Thus, Chapters 1-3 of this Handbook extensively cover the physico-chemical molecular characteristics of the vertebrate rhodopsins. Following photoconversion and G-protein activation, the phototransduction cascade leads to modifications of the population of closed and open ion channels in the photoreceptor plasma membrane, and thereby to the electrical response. The nature of the channels of vertebrate photoreceptors is examined in Chapter 4, and Chapter 5 integrates the present body of knowledge of the activation steps in the cascade into a quantitative framework. Once the phototransduction cascade is activated, it must be subsequently silenced. The various molecular mechanisms participating in inactivation are
treated in Chapters 1-4 and especially Chapter 5. Molecular biology is now an indispensable tool in signal transduction studies. Numerous vertebrate (Chapter 6) and invertebrate (Chapter 7) visual pigments have been characterized and cloned. The genetics and evolutionary aspects of this great subfamily of G-protein activating receptors are intriguing as they present a natural probe for the intimate relationship between structure and function of the visual pigments. Understanding the spectral characteristics from the molecular composition can be expected to

Crustacean Nervous Systems and their Control of Behavior is the third volume of the series The Natural History of the Crustacea. This volume is on the functional organization of crustacean nervous systems, and how those nervous systems produce behavior. It complements other volumes on related topics of feeding biology, reproductive biology, endocrine systems, and behavioral ecology. There is a rich history of the study of the neurobiology of crustaceans, going back over 150 years. This has included studies on how their nervous systems allow them to perform behaviors that are adapted to their particular environments, as well as studying them as model organisms to understand basic biomedical principles about neural function, such as sensory transduction and processing, synaptic transmission and integration, neuromodulation, and learning and memory. The volume has three sections that build progressively on each other. The first section is on the basic organizational features of the crustacean nervous system and the principles upon which it is built. The second section is on sensory ecology - the organization of each sensory system and how it is used in intra- and interspecific interactions, within an ecological context. The third section uses case studies of how crustacean nervous systems are organized to perform complex behaviors and interactions, such as walking, escape, social interactions, and memory and learning. Taken together, the 20 chapters synthesize our modern understanding of the neural control of behavior in crustaceans, based on the most recent technologies in physiological recording, molecular biology, and computational science. This volume will be useful to students and researchers as a concise summary of current knowledge of crustacean neuroscience.

In the last decade, we have witnessed a striking maturation of our understanding of how neurons in the spinal cord control muscular activity and movement. Paradoxically, a host of new findings have revealed an unexpected versatility in the behavior of these well-studied neural elements and circuits. In this volume, the world's leading experts review the current state of our knowledge of motor control, outline their latest results and developments, and delineate the seminal unresolved questions in this vibrant field of research. The volume begins with a commentary and overview of our current understanding of the peripheral and spinal basis of motor control. The remainder of the volume is divided into seven sections, each focused on a different problem. The first chapter in each section provides some historical review and presages the experimental findings and hypotheses that are discussed in subsequent chapters.
Topics include the biomechanics of neuromuscular systems, the properties of motoneurons and the muscle units they control, spinal interneurons, pattern generating circuits, locomotion, descending control of spinal circuits, comparative physiology of motor systems, and motor systems neurophysiology studied in man. The book serves as a unique reference volume and should be essential reading for anyone interested in motor systems. Moreover, the volume's comprehensive coverage of a wide range of topics make it an effective textbook for graduate level courses in motor control neurobiology, kinesiology, physical therapy, and rehabilitation medicine.

These volumes differ from the current conventional texts on bone cell biology. Biology itself is advancing at breakneck speed and many presentations completely fail to present the field in a truly modern context. This text does not attempt to present detailed clinical descriptions. Rather, after discussion of basic concepts, there is a concentration on recently developed findings equally relevant to basic research and a modern understanding of metabolic bone disease. The book will afford productive new insights into the intimate inter-relation of experimental findings and clinical understanding. Modern medicine is founded in the laboratory and demands of its practitioners a broad scientific understanding: these volumes are written to exemplify this approach. This book is likely to become essential reading equally for laboratory and clinical scientists.

Insect physiology is currently undergoing revolutionary changes with the increased application of molecular biological techniques to investigate the molecular mechanisms underlying the physiological responses to insect cells. Advances in Insect Physiology is committed to publishing high quality reviews on molecular biology and molecular genetics in areas where they provide an increased understanding of physiological processes in insects. Volume 27 of this classic series continues to provide up-to-date reviews on topical subjects of importance to all invertebrate physiologists and neurobiologists and contains increased coverage on the molecular biology of insect physiology.

Animal Eyes provides a comparative account of all known types of eye in the animal kingdom, outlining their structure and function with an emphasis on the nature of the optical systems and the physical principles involved in image formation. A universal theme throughout the book is the evolution and taxonomic distribution of each type of eye, and the roles of different eye types in the behaviour and ecology of the animals that possess them. In comparing the specific capabilities of eyes, it considers the factors that lead to good resolution of detail and the ability to function under a wide range of light conditions. This new edition is fully updated throughout, incorporating more than a decade of new discoveries and research.

The last few years have seen a dramatic increase in the number of areas known to be involved in mammalian vision. It has also seen a far greater understanding of the importance of reciprocal connections, intrinsic connections, structure-specific modules and modules which span different structures, as well as the introduction of parallel processing models within the thalamocortical and corticocortical streams.

The body of knowledge has become so vast, and is growing so rapidly, that periodic updates are essential even for experts in the field. This volume is based on a satellite meeting of an international group of researchers. It emphasizes the most current information regarding midbrain and extrastriate mechanisms underlying vision and visually-guided behavior. The book also places these data into the larger context of how interrelated components of the visual system function to produce coherent visual experiences and behavior. New research findings are presented that are unavailable elsewhere, as well as reviews and broad perspectives in which existing data from multiple sources are brought together in order to help understand the structure and function of extrageniculostriate visual areas.

Hansjochem Autrum, einer der Begrunder der vergleichenden Sinnesphysiologie und einer der grossen deutschen Zoologen dieses Jahrhunderts, legt hier seine wissenschaftsgeschichtlich und menschlich hochst interessante Autobiographie vor.
Anschaulich berichtet der Autor von seinem beruflichen Werdegang und von seiner Forschungs- und Lehrtatigkeit an verschiedenen deutschen Universitaten, an deren Wiederaufbau und z.T. Grundung er massgeblich beteiligt war. Er erzahlt von den Menschen, denen er im Laufe seines Lebens begegnet ist und mit denen er zusammen gelebt und gearbeitet hat, von seiner Familie, von Freunden, Kollegen, Vorgesetzten und Mitarbeitern, stets wohlwollend, doch oft mit humorvollem Augenzwinkern."