The IACUC Administrator's Guide to Animal Program Management supports IACUC administrators who assist with developing, managing, and overseeing a program of animal care and animal use. It provides many options and possibilities for specific operational practices (e.g., how to build a well-functioning IACUC, what a functional protocol template looks like) to satisfy regulatory requirements. The material provided is a compilation of several years of Best Practices (BP) meetings among IACUC administrators across the country. The BP meetings included representatives from the NIH/OLAW, AAALAC, and the USDA, whose presence and dialogue assured the BP discussion met or exceeded all regulatory or accreditation minimum standards. BP meeting attendees from private, public, governmental, and academic organizations have helped to shape and develop the information offered herein. It is through the insight of several hundred colleagues-their successes as well as their failures-that the authors have distilled suggestions and considerations for your local animal care and use program. This handbook complements other useful references and manuals regarding programmatic function-it is not intended to replace them. The primary difference you will find is the transparent and open nature of describing processes that have been time tested and proven to help you and your organization satisfy the regulatory requirements.

Nests, Eggs, and Incubation brings together a global team of leading authorities to provide a comprehensive overview of the fascinating and diverse field of avian reproduction. Starting with a new assessment of the evolution of avian reproductive biology in light of recent research, the book goes on to cover four broad areas: the nest, the egg, incubation, and the study of avian reproduction. New research on nest structures, egg traits, and life history is incorporated, whilst contemporary methodologies such as self-contained temperature probes and citizen science are also discussed. Applied chapters describe how biological knowledge can be applied to challenges such as urbanisation and climate change. The book concludes by suggesting priorities for future research. This book builds upon the foundations laid down by Charles Deeming's 2002 work Avian Incubation (available for readers of this book to access online for free), much of which remains relevant today. Read in conjunction with this previous volume, it provides an up-to-date and thorough review of egg biology, nest function, and incubation behaviour, which will be an essential resource for students of avian biology, as well as both professional and amateur ornithologists working in the field of avian reproduction.

The first book to highlight research done by women of color in the field of shark science. A special emphasis is placed on amplifying the voices of Black, Indigenous, People of Color as well as artisanal fishers and economically disadvantaged coastal communities. Accessible to younger readers too, encouraging school children to get into marine science. Covers a broad range of topics including biology, ecology and evolution as well as some less talked about topics like outreach and stakeholder engagement. Interdisciplinary approach to shark science and conservation Easily digestible content for non-experts Focuses on a charismatic group of animals, sharks Offers diverse perspectives and cutting-edge research while diving into issues regarding the decolonization of shark science and changing public perception of sharks. This is an opportunity to challenge the notion that there is only one type of scientist or that scientists look and think a certain way.

The effects of the bone morphogenetic proteins (BMPs) family on bone formation are well documented, but the transforming growth factor (TGF)-beta ( ) isoforms are much less studied. The product of 20 years of study, Induction of Bone Formation in Primates: The Transforming Growth Factor- 3 sums up editor Ugo Ripamonti's research into the osteogenic activity of the three mammalian TGF- isoforms, particularly in primates. It explores how the mammalian TGF- isoforms have the potential to shed light on the apparent redundancy of bone induction signaling. The book unearths the profound and important bone inductive activity of the TGF- 3 isoform. It includes accounts of extensive research in non-human primates from craniofacial tissue regeneration, heterotopic tissue induction, and chapters on periodontal tissue regeneration and synergistic induction of bone formation. It also discusses the future clinical role of the TGF- isoform, including in human studies. This book contributes to the fascinating history of BMP and TGF- research at the intersection of molecular biology, tissue induction, bone regeneration, and craniofacial surgery. It provides a revolutionary awakening to new possibilities in skeletal reconstruction, tissue engineering, and molecular and cellular biology.

Timely title assembling the combined knowledge of some of the leading authorities in the field of small fish reproduction - an important topic for risk assessment and registration of chemical, agricultural, and pharmaceutical compoundsProvides guidance on the microscopic structure of living tissue and evaluation of the reproductive glands of small laboratory fishIncludes state-of-the-art science along with sufficient anatomical and physiological background for understanding and interpreting test resultsHelps standardize the interpretation of results from aquatic bioassays and field observations, which will also clarify inconsistencies in the current scientific literature

Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.

This book on ancient fishes unites the work of many specialists coming from different areas of biology. Hagfishes, lungfishes, Chondrosteans, and Holosteans constitute the main subject of study. Fossil records and extant species are compared to establish the conservation or the degeneration of specific characters. However, phylogenetic relationships have mostly been revisited in the light of new molecular and developmental data. The morphology of several organs is also revisited. This volume includes a phylogenetic account of the cardiac outflow tract, and the particulars of the heart and circulation in lungfishes. The control of breathing and the lung-swim bladder issue is discussed. The developmental anatomy of the sturgeon gut and accounts of the gut structure in lungfishes and garfishes are also included. Biochemical and physiological aspects of the behavior of lungfishes and gars are presented. Reports on the fish olfactory system, and on the amazing slime glands of hagfishes, are also covered.

The third of a planned group of volumes dealing with reptilian nervous systems, Sensorimotor Integration focuses chiefly on visual and sensorimotor aspects of reptilian neurobiology. Chapters examine data for numerous species, drawing together the most current work and thinking on each topic and emphasizing results from recent studies. "This volume would be a valuable addition to any comparative anatomist's bookshelf, and one that should be of great interest to comparative neurobiologists and neuroanatomists alike."--Katherine V. Fite, Quarterly Review of Biology

This comprehensive volume focuses on recent trends and new technologies used in the management of reproduction in major farm animals, focusing on both males and females of bovine, equine, and porcine species. With chapters written by scientists who specialize in their respective topics, the volume presents a selection of different technologies that have been developed to assure reproductive success by improving reproductive efficiency, generating germplasm banks, and maintaining genetic diversity in cattle, horses, and pigs. In the last decade, reproductive technologies in veterinary medicine have progressed considerably, providing high profitability to livestock farms. This book provides basic and applied information on the most used reproductive technologies in bovine, equine, and porcine species for academics, scientists, and veterinarians. The volume discusses reproductive and postpartum management, reproductive ultrasound, sperm management, egg retrieval, artificial insemination, embryo transfer, nutrition, genetics, and certain clinical aspects, such as endocrinology and robustness of reproductive systems.

"Providing a fascinating alternative to the unwieldy life science sources, this book describes how the nervous system (including the brain) communicates with, sends signals to, and receives input from the sensory organs.
Starting with the basic principles and components of the nervous system with sensory receptors, neurons and dendrites, and the skeletal muscle circuits the authors unfold the mystery of this communication with simple, elegant mathematical formulas to enhance your understanding of how the nervous system functions in complicated auditory and visual systems, and the brain.
Includes extensive references at the end of each chapter "
Sponsored by:
IEEE Engineering in Medicine and Biology Society

Intraspecific communication involves the activation of chemoreceptors and subsequent activation of different central areas that coordinate the responses of the entire organism-ranging from behavioral modification to modulation of hormones release. Animals emit intraspecific chemical signals, often referred to as pheromones, to advertise their presence to members of the same species and to regulate interactions aimed at establishing and regulating social and reproductive bonds. In the last two decades, scientists have developed a greater understanding of the neural processing of these chemical signals. Neurobiology of Chemical Communication explores the role of the chemical senses in mediating intraspecific communication. Providing an up-to-date outline of the most recent advances in the field, it presents data from laboratory and wild species, ranging from invertebrates to vertebrates, from insects to humans. The book examines the structure, anatomy, electrophysiology, and molecular biology of pheromones. It discusses how chemical signals work on different mammalian and non-mammalian species and includes chapters on insects, Drosophila, honey bees, amphibians, mice, tigers, and cattle. It also explores the controversial topic of human pheromones. An essential reference for students and researchers in the field of pheromones, this is also an ideal resource for those working on behavioral phenotyping of animal models and persons interested in the biology/ecology of wild and domestic species.

The Association Internationale de Recherche sur la Circulation Osseuse, A.R.C.O., was founded in London in December 1989 by a small group of doctors, surgeons and researchers in basic sciences who had been involved for many years in the study of bone circulation and its disorders. They had met several times in Toulouse, during the International Symposia on Bone Circulation held there since 1973 and they wished to carry their contacts further. In founding A.R.C.O., they established as their primary aims the encouragement and furtherance of research, organisation of meetings and promotion of knowledge on the subject. At the present time, the Association has over a hundred members from more than bone tissue twenty countries in Europe, America and Asia. All have the conviction that and its pathology can only be truly known and studied if one has an understanding of its vascular system and the way its circulation functions. This concept, apparently beyond question, has not yet been adopted by all physicians and scientists who are interested in bone. From time to time, one comes across teaching programmes on bone patho logy which make no mention of bone circulation.

Animal Eyes provides a comparative account of all known types of eye in the animal kingdom, outlining their structure and function with an emphasis on the nature of the optical systems and the physical principles involved in image formation. A universal theme throughout the book is the evolution and taxonomic distribution of each type of eye, and the roles of different eye types in the behaviour and ecology of the animals that possess them. In comparing the specific capabilities of eyes, it considers the factors that lead to good resolution of detail and the ability to function under a wide range of light conditions. This new edition is fully updated throughout, incorporating more than a decade of new discoveries and research.

Ivermectin and abamectin, members of the avermectin family of compounds, were introduced to the market in the 1980's as a veterinary antiparasitic drug and agricultural pesticide, respectively. Their acceptance and commercial success have been remarkable; both are highly effective and in worldwide use. The efficacy of ivermectin in river blindness has expanded the interest in its use in human medicine. In response to the intense scientific and industrial interest in ivermectin and abamectin and the likelihood that they will be forerunners of an expanding family of drugs, this comprehensive monograph satisfies the need for a review and synthesis of current knowledge about the use of these substances in crop protection as well as in cattle, sheep, swine, horses, dogs, cats, birds, fish, reptiles, and in man. This overview presents chemical, biochemical, and microbiological data, as well as pharmacological, safety, and environmental aspects and covers practical use of the compounds as antiparasitic and pesticide agents, as well as the available safety data that have emerged from the clinical experience with human applications.

The GnRH Neuron and its Control examines the developmental biology of GnRH neurons including their birth in the nasal placode of the early embryo, perinatal programming, and sexual differentiation, in addition to the hypothalamic mechanisms that control GnRH neurons in adulthood to generate pulsatile and surge modes of GnRH secretion throughout the major life stages including aging. The morphology, electrophysiology, signal transduction pathways, transcriptional regulators, and genomics underlying function of the adult GnRH neuron is discussed in detail, as is the neuroendocrinology and cell biology governing the generation of both modes of GnRH release. The book also reviews the neurobiological mechanisms and circuitry responsible for the modulation of the activity of GnRH neurons by season, stress, nutrition, and metabolism, and covers the current and potential therapeutic approaches to regulating GnRH secretion and action. Filled with newly identified research and classical fundamental knowledge to GnRH biology, it will provide students, researchers, and practitioners with an in-depth understanding of reproductive neuroendocrinology. This is the fifth volume in the Masterclass in Neuroendocrinology Series, a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.

Birds have colonized almost every terrestrial habitat on the planet - from the poles to the tropics, and from deserts to high mountain tops. Ecological and Environmental Physiology of Birds focuses on our current understanding of the unique physiological characteristics of birds that are of particular interest to ornithologists, but also have a wider biological relevance. An introductory chapter covers the basic avian body plan and their still-enigmatic evolutionary history. The focus then shifts to a consideration of the essential components of that most fundamental of avian attributes: the ability to fly. The emphasis here is on feather evolution and development, flight energetics and aerodynamics, migration, and as a counterpoint, the curious secondary evolution of flightlessness that has occurred in several lineages. This sets the stage for subsequent chapters, which present specific physiological topics within a strongly ecological and environmental framework. These include gas exchange, thermal and osmotic balance, 'classical' life history parameters (male and female reproductive costs, parental care and investment in offspring, and fecundity versus longevity tradeoffs), feeding and digestive physiology, adaptations to challenging environments (high altitude, deserts, marine habitats, cold), and neural specializations (notably those important in foraging, long-distance navigation, and song production). Throughout the book classical studies are integrated with the latest research findings. Numerous important and intriguing questions await further work, and the book concludes with a discussion of methods (emphasizing cutting-edge technology), approaches, and future research directions.

Life evolves in a cyclic environment, and to be successful, organisms must adapt not only to their spatial habitat, but also to their temporal habitat. How do plants and animals determine the time of year so they can anticipate seasonal changes in their habitats? In most cases, day length, or photoperiod, acts as the principal external cue for determining seasonal activity. For organisms not living at the bottom of the ocean or deep in a cave, day follows night, and the length of the day changes predictably throughout the year. These changes in photoperiod provide the most accurate signal for predicting upcoming seasonal conditions. Measuring day length allows plants and animals to anticipate and adapt to seasonal changes in their environments in order to optimally time key developmental events including seasonal growth and flowering of plants, annual bouts of reproduction, dormancy and migration in insects, and the collapse and regrowth of the reproductive system that drives breeding seasons in mammals and birds.
Although research on photoperiodic time measurement originally integrated work on plants and animals, recent work has focused more narrowly and separately on plants, invertebrates, or vertebrates. As the fields have become more specialized there has been less interaction across the broader field of photoperiodism. As a result, researchers in each area often needlessly repeat both theoretical and experimental work. For example, understanding that there are genetically distinct morphs among species that, depending on latitude, respond to different critical photoperiods was discovered separately in plants, invertebrates, and vertebrates over the course of 20 years. However, over the past decade, intense work on daily and seasonal rhythms in fruit flies, mustard plants, and hamsters and mice, has led to remarkable progress in understanding the phenomenology, as well as the molecular and genetic mechanisms underlying circadian rhythms and clocks. This book was developed to further this type of cooperation among scientists from all related disciplines. It brings together leading researchers working on photoperiodic timing of seasonal adaptations in plants, invertebrates, and vertebrates. Each of its three sections begins with an introduction by the section editor, and at the end of the book, the section editors present a synthesis of common themes in photoperiodism, as well as discuss similarities and differences in approaches to the study of photoperiodism, and future directions for research on photoperiodic time measurement.

Offers the first comprehensive resource to document the particular needs of a given species in captivity. Each species is dealt with by specialists who are fully familiar with their animals, writing to a consistent template to facilitate easy navigation. Each chapter in Part 2 addresses specific species-typical behaviours associated with pain and distress. The third section contains a series of easy reference ethograms that will aid understanding, and potentially quantification of i.e., baboon, bird, or bovine behavior. The book will be useful not only in laboratory settings, but any situation where an animal is kept in captivity, from veterinary clinics to zoos and sanctuaries. Edited by internationally recognized experts in animal behaviour and behavioural management.

Why do males and females frequently differ so markedly in body size and morphology?
Sex, Size, and Gender Roles is the first book to investigate the genetic, developmental, and physiological basis of sexual size dimorphism found within and among the major taxonomic groups of animals. Carefully edited by a team of world-renowned specialists in the field to ensure a coherence of style and approach between chapters, it presents a compendium of studies into the evolution, adaptive significance, and developmental basis of gender differences in body size and morphology. Adaptive hypotheses allude to gender-specific reproductive roles and associated differences in trophic ecologies, life history strategies, and sexual selection. This "adaptationist" approach is balanced by more mechanistic studies of the genetic, developmental and physiological basis of sexual size dimorphism to provide a comprehensive and authoritative overview of the subject. Throughout the volume the emphasis is on sexual dimorphism in overall size; however, the scope of enquiry encompasses gender differences in body shape, the size and structure of secondary sexual characteristics, patterns of growth (ontogeny), and patterns of gene regulation.
This advanced, research level text is suitable for graduate level students and researchers in the fields of evolutionary biology, behavioral ecology, physiology, developmental biology, and genetics. It will also be of relevance and use to non-biologists from fields such as anthropology and gender studies.
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The Racehorse: A Veterinary Manual has become the definitive text for primary care of the Thoroughbred racehorse. Written by one of the world’s leading racehorse veterinary clinicians, it sets out best practice standards of diagnosis and management of all the major conditions likely to be encountered in racehorse clinical practice, as well as comprehensively reviewing subjects as diverse as pre-purchase assessment and exercise physiology. This second edition has been thoroughly updated and introduces new chapters on a range of topics including injury risk assessment and electrolyte and fluid therapy, expanded sections on nutrition, rehabilitation and sales radiography as well as an array of new images and ready reference charts. The Racehorse: A Veterinary Manual remains an invaluable resource for both clinicians and non-veterinarians in the racing industry.

Awarded 4 stars (rated 90/100) by Doody's Book Reviews! Fish are critically important to the welfare of this planet and its occupants, the health of both wild and captive fish populations paramount to our survival. This book presents the gross pathology of the most commonly encountered diseases and syndromes of fish in an organ system-based approach. It provides an overview of the diseases and disorders of tropical, ornamental, bait and food fish from freshwater, brackish and marine environments. Readers will gain a broader understanding of the basic biology of infectious and non-infectious diseases in fish, as well as novel diagnostic techniques and innovative disease control methods. Over 300 high-quality color photographs illustrate the conditions described Nineteen chapters by expert international contributors provide the veterinarian, fish health professional, fisheries biologist and fish researcher with an understanding of anatomy, water quality, diagnostic methodology, and basic clinical medicine of fish. Each organ system chapter provides an overview of the most common diseases or syndromes the etiological agent route of transmission typical host range clinical presentation possible differentials most current means of diagnosis for that particular problem potential management and control methods This text will serve as a resource for the identification and control of fish diseases in a multitude of settings, from aquarium fish, to home ponds, to aquaculture species, to research fish and to even wild fish populations.

This is the first book to summarize the methods, conceptual issues and results of studies using the interpretation of feather growth rates as an index to nutritional condition in birds. The author has coined the term ptilochronology (literally. 'the study of feather time') to describe this technique, which relies on the fat that as a feather grows it produces visible growth bars. Both the technique and its conceptual foundations have been applied worldwide to numerous studies of avian evolution, ecology, and conservation biology. the author reviews this work, chronicles the various criticisms that have been amde, and describes how these have influenced the development of ptilochronology. He goes on to suggest experimental methodologies and analytical techniques to safeguard against invalid results. a final chapter summarises this new technique's contribution to avian biology, and suggests potential applications and a future research agenda. an appendix details specific measurements and describes the methodology associated with ptilochronology.
Ptilochronology provides a practical resource as well as a conceptual understanding of how this technique can be used to address important questions in avian biology. It will be of relevance and use to professional avian biologists and ornithologists as well as to graduate students of avian behavioural ecology, evolution and conservation.

This book is the only account of what honeybees actually see. Bees detect some visual features such as edges and colours, but there is no sign that they reconstruct patterns or put together features to form objects. Bees detect motion but have no perception of what it is that moves, and certainly they do not recognize "things" by their shapes. Yet they clearly see well enough to fly and find food with a minute brain. Bee vision is therefore relevant to the construction of simple artificial visual systems, for example for mobile robots. The surprising conclusion is that bee vision is adapted to the recognition of places, not things. In this volume, Adrian Horridge also sets out the curious and contentious history of how bee vision came to be understood, with an account of a century of neglect of old experimental results, errors of interpretation, sharp disagreements, and failures of the scientific method. The design of the experiments and the methods of making inferences from observations are also critically examined, with the conclusion that scientists are often hesitant, imperfect and misleading, ignore the work of others, and fail to consider alternative explanations. The erratic path to understanding makes interesting reading for anyone with an interest in the workings of science but particularly those researching insect vision and invertebrate sensory systems.

This book accompanies Infectious Diseases and Pathology of Reptiles, Second Edition to cover noninfectious diseases of reptiles, meeting the need for a similar, authoritative single-source reference. The volume features color photos of normal anatomy and histology, as well as gross, light, and electron microscopic imagery of diseases. Subjects range from neoplasia, nutrition, and metabolic disease, and deposition disorders to developmental anomalies, trauma, and physical diseases, and the unique contribution of paleopathology and diseases of bone. Each chapter is supported by numerous figures, many of which are unique and cannot be found in the published literature. Readers will note that some of the chapters are based on organ system, a trend that will continue into the next edition to encompass all of the basic organ systems. This book holds the most information ever accrued into one publication on noninfectious diseases and pathology of this class of animals, providing information on every aspect of the anatomy, pathophysiology, and differential diagnosis. With up-to-the-minute data, a never-before-seen collection of images, and a stellar panel of contributors, Noninfectious Diseases and Pathology of Reptiles is the definitive resource for veterinarians, biologists, and researchers involved in the study of reptile diseases.

In this authoritative three-volume reference work, leading researchers bring together current work to provide a comprehensive analysis of the comparative morphology, development, evolution, and functional biology of the skull.

Through its emphasis on recent research, its many summary tables, and its bibliography of more than 4,000 entries, this first modern, synthetic treatment of comparative amphibian environmental physiology emerges as "the" definitive reference for the field. Forty internationally respected experts review the primary data, examine current research trends, and identify productive avenues for future research.