The maintenance of a stable acid-base status within biological tissue is a fundamental homeostatic process in all organisms, necessary to preserve the metabolic function of proteins and other macromolecules. The study of acid-base regulation has advanced enormously over recent decades due to the development of increasingly accurate and sensitive techniques for measuring acid-base variables. This volume brings together contributions from leading comparative physiologists working on factors affecting the acid-base status of the internal fluids of animals and plants. The result is a broad-ranging, authoritative and accessible review of the most recent and exciting discoveries in this area, together with a critical look at current techniques and tools.

The cestodes, or tapeworms, are a group of parasitic worms many species of which cause serious, often fatal, diseases in man and domestic animals throughout the world. This book is an updated and expanded version of Professor Smyth's The Physiology of Cestodes (1969). The text has now been entirely rewritten, taking into account advances in investigative techniques such as immunocytochemistry, in vitro culture and scanning electron microscopy, which have immensely increased our understanding of these organisms. The biochemical coverage now includes the spectacular advances in molecular biology that have occured. The book also shows how cestodes are increasingly being recognized as valuable models for investigating fundamental biological phenomena such as membrane transport and asexual/sexual differentiation. Students of medicine, veterinary medicine, parasitology and zoology will find this book invaluable. Its high research content and extensive references also make it an essential reference book for researchers in these fields.

From a human viewpoint, the cold waters of deep sea and polar marine regions present an inhospitable and harsh environment for life. The study of organisms which have exploited this seemingly hostile ecological niche has revealed intriguing physiological adaptations. This volume summarizes the information on the adaptations exhibited by representatives of the main groups of polar animals, including marine invertebrates, fish, mammals and birds, at scales ranging from the whole organism through to the underlying molecular adaptational mechanisms. Unique in its breadth of coverage, this volume will provide an important resource for all those concerned specifically with how animals have adapted to life in extreme conditions, as well as being of general interest to all marine biologists.

Wild animals survive in a variety of complex environments; they are exposed to predictable and unpredictable changes in their particular environment on a daily or seasonal basis. However, we live in a time when almost all natural environments are undergoing relatively rapid change, and many of these changes, such as the pollution of air and water, removal of natural food sources, environment fragmentation, and climate change, are the result of human activity. Animal Physiology: an environmental perspective shows how an understanding of the physiology of animals in their natural habitats helps us to understand not only how and why animals evolved the way they did, but how we can act to protect at least some of them from the extreme effects of the changes affecting their environments. Part One sets the foundation for the topics covered in the remainder of the book by introducing a range of fundamental processes that are essential to life. It considers the diversity of habitats on Earth in which animals live, and examines animal groups and their evolutionary relationships. It then explores the different feeding strategies used by animals to obtain the energy they require to carry out all the essential functions of life, and how animals convert the chemical energy in food molecules into the energy they need to power all body functions. Finally, it explores the general properties of animal cells, and how animals maintain a suitable internal environment in which their cells are protected from external influences. We then examine those fundamental principles governing the main exchanges between the cells within animals, and between an animal and its environment. Parts two to four of the book explore how different organ systems - respiratory and circulatory systems, excretory organs and endocrine systems - enable animals to interact with their environment, and how environmental temperature profoundly affects the physiology of animals. Part five considers how the sensory and nervous systems provide animals with information on their internal as well as their external environment, and how they, together with the endocrine system, are involved in the control and co-ordination of muscles, reproduction, salt and water balance, and the cardio-respiratory systems. Digital formats and resources Animal Physiology: an environmental perspective is supported by online resources and is available for students and institutions to purchase in a variety of formats. The e-book offers a mobile experience and convenient access along with functionality tools, navigation features and links that offer extra learning support: www.oxfordtextbooks.co.uk/ebooks The book's online resources include: For students: - Original articles: a list of original articles consulted during the writing of each chapter so that you can explore the original research for yourself. - Additional case studies and experimental approach panels to augment those in the printed book. - Answers to numerical questions: full solutions to numerical questions so that you can verify your working. For registered adopters of the text: - Digital image library: Includes electronic files in JPG format of every illustration, photo, graph and table from the text

Comprising well over half of all known animal species, insects are the most successful organisms on the planet. Indeed, it is no exaggeration to say that one cannot study agriculture, biology, and the environment, without a basic understanding of entomology. Furthermore, insects are indispensable to advances in molecular biology and genetics, and their ongoing decline in many parts of the world has stimulated much research in the crucial roles they play in global ecosystems. However, the sheer diversity of insects can be a challenge to every newcomer to entomology. Most entomology textbooks tend to focus on insect biology, leaving readers with only a superficial idea of insect diversity and evolution, while others delve into too much detail that will deter the novice. In contrast, Essential Entomology has a clear taxonomic structure that provides readers with the necessary framework to understand the diversity, life history, and taxonomy of insects in a new light. This fully revised edition provides the most up-to-date guide to insects and includes all the major developments in molecular biology and palaeontology of the last 20 years. This textbook is an essential read for undergraduate and graduate students taking courses in entomology, agriculture, and forestry. It will also appeal to a broad academic audience of ecologists, conservationists, natural resource managers, as well as to the far more numerous general readers who are interested in wildlife, nature, and the environment. With these diverse audiences in mind, the straightforward and accessible style of the first edition has been maintained, technical jargon has been kept to a minimum, and sufficient background information is provided to enable the reader to follow the text with ease.

Primate dentitions vary widely both between genera and between species within a genus. This book is a comparative dental anatomy of the teeth of living non-human primates that brings together information from many disciplines to present the most useful and comprehensive database possible in one consolidated text. The core of the book consists of comparative morphological and metrical descriptions with analyses, reference tables and illustrations of the permanent dentitions of 85 living primate species to establish a baseline for future investigations. The book also includes information on dental microstructure and its importance in understanding taxonomic relationships between species, data on deciduous dentitions, prenatal dental development and ontogenetic processes, and material to aid age estimation and life history studies. Primate Dentition will be an important reference work for researchers in primatology, dental and physical anthropology, comparative anatomy and dentistry as well as vertebrate paleontology and veterinary science.

Respiration represents the major area of ignorance in our understanding of the global carbon cycle. In spite of its obvious ecological and biogeochemical importance, most oceanographic and limnological textbooks invariably deal with respiration only superficially and as an extension of production and other processes. The objective of this book is to fill this gap and to provide the first comprehensive review of respiration in the major aquatic systems of the biosphere. The introductory chapters review the general importance of respiration in aquatic systems, and deal with respiration within four key biological components of aquatic systems: bacteria, algae, heterotrophic protists, and zooplankton. The aim of this first part is to provide the backbone for the analysis and interpretation of ecosystem-level respiration in a variety of aquatic environments. The central chapters of the book review respiration in major aquatic ecosystems including freshwater wetlands, lakes and rivers, estuaries, coastal and open ocean and pelagic ecosystems, as well as respiration in suboxic environments. For each major ecosystem, the corresponding chapter provides a synthesis of methods used to assess respiration, outlines the existing information and data on respiration, discusses its regulation and link to biotic and abiotic factors, and finally provides regional and global estimates of the magnitude of respiration. The final chapter provides a general synthesis of the information and data provided in the different sections, and further attempts to place aquatic respiration within the context of the global carbon budget.

In most terrestrial and aquatic habitats, the vast majority of animals transmitting and receiving communicative signals are arthropods. This book presents the story of how this important group of animals use pheromones, sound, vibration, and light for sexual and social communication. Because of their small to minute body size most arthropods have problems sending and receiving acoustic and optical information, each of which have their own severe constraints. Because of these restraints they have developed chemical signaling which is not similarly limited by scale. Presenting the latest theoretical and experimental findings from studies of signaling, it suggests that close parallels between arthropods and vertebrates reflect a very limited number of solutions to problems in behavior that are available within the confines of physical laws.

The book discusses the controversial issue of whether animals are designed according to the same rules that engineers use in building machines, namely that materials and energy are used economically while attempting to achieve a high level of performance. There is considerable scientific controversy surrounding this question because, although there is much evidence suggesting that animals are indeed well designed, evolutionary biology tells us that animals are not 'engineered' but result from evolution by natural selection. This book collates this evidence which is discussed by a group of eminent biologists from many different biological disciplines."

What is it that stops the process of eating? This deceptively simple question lies at the centre of Satiation: From Gut to Brain, and the book succeeds in answering it comprehensively while incorporating the latest scientific research. Unless we stop eating by choice-for medical or social reasons-an unconscious physiological process is triggered through negative feedback from ingested food as it travels from the mouth through the stomach and on to the small intestine. This process is called satiation. Recent scientific evidence has revealed that food stimuli activate this process before the actual absorption of digested food, which significantly changes the traditional perspective that satiation depends on the post-absorptive repletion of metabolic fuels. This volume presents the first detailed account of the neurobiological mechanisms of satiation. The ten chapters of the book detail the neural, endocrine, and cellular underpinnings of the process. Authors expert in different aspects of satiation have compiled a critical overview of recent advances and current problems in this field. The inclusion of a chapter on the satiation of alcohol is unique in a book on food intake, and shows the convergence of ideas on satiation in these two areas. Comprehensive in scope and accessible to a wide array of advanced students and professonals, Satiation: From Gut to Brain is an authoritative and up-to-date review of every aspect of this important physiological process. Although intended primarily for neuroscientists, nutritionists, and psychobiologists, who will find it most pertinent to their work, the book will also be useful for physiologists, pharmacologists, and psychologists concerned with eating and its disorders.

Environmental temperature varies in time and space on timescales ranging from a few hours to long-term climate change. Organisms are therefore continually challenged to regulate and maintain functional capacities as their thermal environment changes. This volume brings together many of the leading workers in thermal biology, with backgrounds spanning the disciplines of molecular biology, cell biology, physiology, zoology, ecology and evolutionary biology, to discuss the responses of a wide range of species to temperature change at all scales of organization, ranging through the molecular, cellular, organismal, population and ecosystem levels. The volume provides an important and comprehensive contribution to the study of temperature adaptation, which, given the concern about global climate change, will provide much to interest a wide range of biologists.

Ion channels are crucial components of living cells. Situated in the cell membrane, they allow ions to pass from one side of the membrane to the other. This book provides an overview of ion channel study, including up-to-date coverage of the permeability and selectivity of channels, their gating and modulation, their response to drugs and toxins, and the human diseases that result from channel malfunction. Students of molecular biology, biochemistry, physiology, and neurobiology will benefit from this modern, concise text.

Bioenergetics is the name given to the collection of disciplines within biochemistry and physiology that aims at a description and understanding of the function of living systems. These functions include the exchange, metabolism and accumulation of matter, as well as their related energy transformations. The authors present an accessible textbook, providing the reader with the fundamental principles of the subject and how these can then be applied to practical problems. This textbook is ideal for graduate students and researchers in biochemistry, physiology and chemistry. The book should also be of interest to workers in the applied life sciences.

In most animals, from bees to bulls, mice to men, it is possible to see at a glance whether an individual is male or female. How and why these differences in appearance and behavior developed and the nature and extent of the differences between males and females is a complex subject. This book reviews the latest molecular, genetic, hormonal, anatomical, and behavioral data in a wide range of species in a series of lively and highly readable articles from the world's leading experts in this field. Unashamedly Darwinian, this book brings sexual selection up to date and discusses not only a dazzling array of differences between the sexes, but probes the mechanisms by which they are produced and the adaptive significance of the differences themselves. It should have a wide appeal, especially to undergraduates and graduates in the biological and medical sciences, and should help to bridge the gap between those who study genes and molecules in the laboratory and those who study the behavior of animals in the wild.

As a student in Cambridge, Alan Hodgkin first became interested in the basis of nerve conduction, using single nerve fibers from a shore crab in his experiments. In 1963, he won the Nobel prize for his work on nerve conduction, and in 1970 became President of the Royal Society. Chance and Design is a fascinating chronicle of Hodgkin's life, providing a glimpse into the world of Cambridge undergraduates in the thirties, the motivation behind his research into nerve conduction, his work on centimeter radar during World War II, and his life as a Cambridge academic after the war. The book concludes with an account of the Nobel prize ceremony in 1963. This highly readable autobiography gives an insight into the working patterns and private life of an eminent scientist, and will appeal not only to scientists, but also to those interested in gaining an understanding of what inspires scientific research.

This is an extensive collection of essays on all aspects of vision, approached from the perspective of coding and efficiency. It examines the broad spectrum of vision research from one particular, unifying viewpoint, namely the way that visual systems efficiently encode and represent the outside world. This approach, both rigorous and general, was championed by H.B. Barlow in the fifties and has been followed in many areas of vision research. The approach has recently acquired new significance due to the growing interest of computer science and artificial intelligence in the processes of vision, which attempts to describe visual processes in algorithmic terms, equally relevant to a robotic visual system, the eye of a fly or the complex visual pathways in the human brain.

This text is a graduate-level introduction to neural networks, focusing on current theoretical models, examining what these models can reveal about how the brain functions, and discussing the ramifications for psychology, artificial intelligence, and the construction of a new generation of intelligent computers. The book is divided into four parts. The first part gives an account of the anatomy of the central nervous system, followed by a brief introduction to neurophysiology. The second part is devoted to the dynamics of neuronal states, and demonstrates how very simple models may stimulate associative memory. The third part of the book discusses models of learning, including detailed discussions on the limits of memory storage, methods of learning and their associated models, associativity, and error correction. The final section of the book reviews possible applications of neural networks in artificial intelligence, expert systems, optimization problems, and the construction of actual neuronal supercomputers, with the potential for one-hundred fold increase in speed over contemporary serial machines.

This book is a practical guide for researchers and advanced graduate students in biology and biophysics who need a quantitative understanding of acoustical systems such as hearing, sound production, and vibration detection in animals at the physiological level. It begins with an introduction to physical acoustics, covering the fundamental concepts and showing how they can be applied quantitatively to understand auditory and sound-producing systems in animals. Only after the relatively simple mechanical part of the system is explained does the author focus his attention on the underlying physiological processes. The book is written on three levels. For those wanting a brief survey of the field, each chapter begins with a nonmathematical synopsis which summarizes the content and refers to the figures, all of which are designed to be understood apart from the main text. At the next level, the reader can follow the main text, but need not give close attention to anything but the general concepts and techniques involved. At the third level, the reader should follow the mathematical arguments in detail and attempt the discussion of questions at the end of each chapter. The author has provided detailed solutions which serve to expand the discussions of particular cases.

This book is composed of a set of chapters contributed by past and present collaborators of the Nobel laureate Sir Andrew Huxley, covering the areas of muscle research to which he has made major contributions. The purpose of the book is to discuss the way that muscle works, asking questions at a fundamental level about the molecular basis of muscle tone production and muscle contraction. The majority of the chapters are concerned with muscle physiology and the relation between structure and function. The process of activation of muscle is dealt with, together with the mechanism of contraction itself. Although most of the book concerns itself with vertebrate skeletal muscle, several of the chapters deal with cardiac muscle. The book also features two introductory chapters discussing Sir Andrew's achievements in both nerve and muscle physiology. All those interested in the structure and function of muscle, or cell motility in general, will wish to read this book.

There is often confusion over the meaning and usage of terms such as efficiency, economy, effectiveness, optimization, and perfection in biology. This book defines and discusses these concepts within a broad evolutionary perspective and considers how evolutionary pressures can affect the economy and efficiency of animals. Chapters consider biomaterials, skeletal systems, muscular function, aquatic and terrestrial locomotion, and cardiovascular systems. The result is a book of interest to all biologists, particularly those working in the field of comparative physiology and evolutionary biology.

Originally published in 1991, this book reviews the various metabolic and functional mechanisms that animals possess in order to live successfully in their own particular, often unique, environments. The book's purpose is to demonstrate both the diversity of responses that are shown (be they biochemical, physiological or behavioural) and to demonstrate the underlying principles of gas exchange and transport for a wide range of diverse organisms. What results is a useful review and analysis of our modern understanding of the respiratory physiology of helminths, crustacea, amphibians, reptiles, birds and mammals. The approach taken by the editors is essentially comparative and the individual authors were chosen so as to provide a useful, complementary view of the subject.

This book gives a concise account of the physiology and form of the fish circulatory system. The emphasis is primarily on function, but details of structure have been included. Following a revision of ideas on hemodynamics, attention is focused on the heart as the primary pump in the fish circulatory system. The fine structure and the electrical and ionic events of cardiac myocytes are described and the major events of the cardiac cycle are outlined. The structure of the peripheral vessels then follow and attention is devoted to the circulation in certain special areas such as the gills, the renal portal system, and the secondary blood system. There are also chapters devoted to the blood and the hemopoetic tissues and an account is given of the different types of retial systems that concentrate oxygen or heat in various parts of the body. Following a description of the autonomic nervous system, the circulatory responses to exercise and hypoxia are described. The book concludes with a discussion on the circulation of hagfish and how it illuminates our understanding of the functional and structural evolution of the circulatory system.

Pursuing the questions of how we learn and how memory is made, Edward Kosower introduces a novel and rich approach to connecting molecular properties with the biological properties that enable us to write and read, to create culture and ethics, and to think. Here he examines what happens within a single cell in reaction to external stimuli, and shows the parallels between single cell and multicellular responses. To address the problem of "learning," Kosower explains the molecular mechanisms of responses to input from taste, olfactory, and visual receptors. He then shows how these and other processes serve as the basis for memory. This study covers such signals for the molecular process of learning as pheromones (the molecular signals mediating behavior), light (activates the G-protein receptor, rhodopsin), and acetylcholine (opens the nicotinic acetylcholine receptor). Kosower's discussion of the structure and function of these complex molecules has direct implications for such areas as molecular neurobiology, bioorganic chemistry, and drug design, in elucidating approaches to the structure of drug targets. Originally published in 1991. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Covering the psychological aspects of ergonomics, this volume places considerable emphasis on the radical changes in work practices over the past twenty years stimulated by high technology systems and computerization. Ergonomics is a multidisciplinary activity concerned mainly with people at work, but also with other human purposeful activities such as war, sports, games and leisure. The objective of ergonomics is to make these activities more effective and safer by applying established principles of anatomy, physiology and psychology. Together with Singleton's earlier volume, The Body at Work, this book forms a comprehensive textbook of ergonomics. This is a useful text for undergraduate and graduate students of psychology, physiology, management, social sciences, engineering, industrial design, computer science and information technology.

An essential introduction to microbiome science, a new cutting-edge discipline that is transforming the life sciences This book provides an accessible and authoritative guide to the fundamental principles of microbiome science, an exciting and fast-emerging new discipline that is reshaping many aspects of the life sciences. Resident microbes in healthy animals--including humans-can dictate many traits of the animal host. This animal microbiome is a second immune system conferring protection against pathogens; it can structure host metabolism in animals as diverse as reef corals and hibernating mammals; and it may influence animal behavior, from social recognition to emotional states. These microbial partners can also drive ecologically important traits, from thermal tolerance to diet, and have contributed to animal diversification over long evolutionary timescales. Drawing on concepts and data across a broad range of disciplines and systems, Angela Douglas provides a conceptual framework for understanding these animal-microbe interactions while shedding critical light on the scientific challenges that lie ahead. Douglas explains why microbiome science demands creative and interdisciplinary thinking-the capacity to combine microbiology with animal physiology, ecological theory with immunology, and evolutionary perspectives with metabolic science. An essential introduction to a cutting-edge field that is revolutionizing the life sciences, this book explains why microbiome science presents a more complete picture of the biology of humans and other animals, and how it can deliver novel therapies for many medical conditions and new strategies for pest control.