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Books > Science & Mathematics > Biology, life sciences > Zoology & animal sciences > Animal physiology

Atlas of the Developing Rat Nervous System (Hardcover, 4th edition): George Paxinos, Ken W.S. Ashwell Atlas of the Developing Rat Nervous System (Hardcover, 4th edition)
George Paxinos, Ken W.S. Ashwell
R4,036 R3,091 Discovery Miles 30 910 Save R945 (23%) Ships in 12 - 17 working days

Paxinos and Ashwell's Atlas of the Developing Rat Nervous System, Fourth Edition, builds on the many excellent features of previous editions that have made this book the most cited atlas of the developing rat brain. It provides the most comprehensive depiction of not only the structures in the brain and spinal cord, but also of the peripheral nervous system and target organs that are important for developmental neurobiologists, allowing the user to follow neural structures through the developing embryo in both time and space. The nomenclature and identification of structures in this edition have been thoroughly updated to ensure accuracy and compatibility.

The Welfare of Cattle (Hardcover): Bernard E. Rollin, Terry Engle, Donald J. Klingborg, DVM The Welfare of Cattle (Hardcover)
Bernard E. Rollin, Terry Engle, Donald J. Klingborg, DVM
R4,747 Discovery Miles 47 470 Ships in 12 - 17 working days

Contains a selection of White Papers, commissioned to better inform the exploration of cattle welfare. These are prepared by notable experts in their field, to help provide factual context around selected topics that impact cattle welfare and production systems. Covers all aspects of cattle use in an accessible style, making this a must have volume for anyone interested in cattle welfare or cattle medicine. Provides an in-depth picture of the distinctive beef and dairy cattle welfare practices and issues, covering topics such as behavior, breeding and genetic manipulation, nutrition and feeding, housing and management, health and disease, and transport and slaughter. Written by acknowledged leaders in animal science, veterinary science, philosophy and animal welfare, presenting a truly multidisciplinary perspective on cattle welfare. Includes a section on understanding and managing animal welfare in both beef and dairy cattle, discussing how cattle perceive the world, animal handling and pain mitigation, and how to assure that the cows have a reasonably good life. The Welfare of Cattle offers an accurate, detailed account of the ethical and welfare concerns related to the human use of cattle. There is currently no significant book dealing with the welfare of cows, animals often seen as archetypal paradigms of 'farm animals'. Covering both beef and dairy cattle, the expert authors provide in-depth information on the husbandry roots of traditional agriculture, the replacement of this system of stewardship by an industrial model, and the resulting welfare challenges associated with industrial agriculture: feedlots, highly industrialized dairies, and slaughterhouses killing huge numbers of animals who have been transported great distances. This important book explores in detail the ways in which people who are providing care for cattle can take their first step, or their next step, toward enhancing the welfare of these animals. An extra chapter (online only) is available in the 'Downloads' tab on the left: Dairy Nutrition, by Michael Gamroth

The Life Cycle of the Corpus Luteum (Paperback, Softcover reprint of the original 1st ed. 2017): Rina Meidan The Life Cycle of the Corpus Luteum (Paperback, Softcover reprint of the original 1st ed. 2017)
Rina Meidan
R4,228 Discovery Miles 42 280 Ships in 10 - 15 working days

This book describes the life cycle of a unique endocrine gland that is absolutely essential for the establishment and maintenance of pregnancy in all mammalian species. The corpus luteum is unique because it is formed and destroyed every (non-fertile) reproductive cycle. When fertilization occurs, the corpus luteum is rescued or maintained. The processes that control corpus luteum formation, demise (luteolysis), or maintenance are just beginning to be unraveled in recent years; they involve diverse cell types and mechanisms. Some of these processes resemble tumor development-angiogenesis, for instance-but interestingly enough, this resemblance is only up to a point. The corpus luteum uses mechanisms that allow its normal, physiological growth and disappearance. Pulling together key research on the corpus luteum, this volume is of interest to both reproductive endocrinologists and comparative physiologists, with clinical relevance spanning comparative animal studies to women's health.

The Hot-Blooded Insects - Strategies and Mechanisms of Thermoregulation (Paperback, Softcover reprint of the original 1st ed.... The Hot-Blooded Insects - Strategies and Mechanisms of Thermoregulation (Paperback, Softcover reprint of the original 1st ed. 1993)
Bernd Heinrich
R2,623 R2,430 Discovery Miles 24 300 Save R193 (7%) Ships in 9 - 15 working days

"From one man's persistent and elegant probing of the temperature biology of bees, we have been led to a deeper understanding of the whole biology of many insect taxa, and of their interactions with ecological and environmental stresses: all who work at the interfaces of physiology, ecology and behaviour have cause to be grateful, and all should certainly read this book." (Trends in Ecology & Evolution) "An outstanding source of information, and can be read with profit and satisfaction by the professional biologist and interested amateur alike." (Nature)

Exploring Animal Behavior Through Sound: Volume 1 - Methods (Hardcover, 1st ed. 2022): Christine Erbe, Jeanette A. Thomas Exploring Animal Behavior Through Sound: Volume 1 - Methods (Hardcover, 1st ed. 2022)
Christine Erbe, Jeanette A. Thomas
R1,319 Discovery Miles 13 190 Ships in 12 - 17 working days

This open-access book empowers its readers to explore the acoustic world of animals. By listening to the sounds of nature, we can study animal behavior, distribution, and demographics; their habitat characteristics and needs; and the effects of noise. Sound recording is an efficient and affordable tool, independent of daylight and weather; and recorders may be left in place for many months at a time, continuously collecting data on animals and their environment. This book builds the skills and knowledge necessary to collect and interpret acoustic data from terrestrial and marine environments. Beginning with a history of sound recording, the chapters provide an overview of off-the-shelf recording equipment and analysis tools (including automated signal detectors and statistical methods); audiometric methods; acoustic terminology, quantities, and units; sound propagation in air and under water; soundscapes of terrestrial and marine habitats; animal acoustic and vibrational communication; echolocation; and the effects of noise. This book will be useful to students and researchers of animal ecology who wish to add acoustics to their toolbox, as well as to environmental managers in industry and government.

Concise Textbook of Large Animal Handling - A Practical Handbook (Paperback): C. B. Chastain Concise Textbook of Large Animal Handling - A Practical Handbook (Paperback)
C. B. Chastain
R1,213 Discovery Miles 12 130 Ships in 12 - 17 working days

This concise instructional guide condenses the most important aspects of large animal handling. It provides a portable, durable, beside-the-animal means of learning, as well as a convenient way to refresh on how to strive for safety and efficacy in animal handling techniques. It is ideal for use during veterinary placements in all settings from farm to laboratory, to riding school. The text covers: * Handler safety * Animal safety * Sanitation * Approach and capture * Routine handling and release procedures * Handling for medical procedures * Use and supply sources of restraint equipment. A Companion Website provides additional self-assessment questions and answers to aid learning Important reading for undergraduate veterinary students on EMS rotations, as well as practicing veterinarians, technicians and assistants, the book covers species encountered in farm, equine and laboratory settings.

Electroporation in Veterinary Oncology Practice - Electrochemotherapy and Gene Electrotransfer for Immunotherapy (Hardcover,... Electroporation in Veterinary Oncology Practice - Electrochemotherapy and Gene Electrotransfer for Immunotherapy (Hardcover, 1st ed. 2021)
Joseph A. Impellizeri
R2,308 R2,143 Discovery Miles 21 430 Save R165 (7%) Ships in 9 - 15 working days

This is the first edited collection on veterinary applications of electroporation. Written by an international team of experts, this book presents worldwide emerging therapy options for cancer treatments in veterinary oncology practice. Electroporation offers a precision tool to target cancer cells without destroying surrounding tissue structures. The opening of tumor cell membranes facilitates local control of solid tumors either through the delivery of chemotherapeutics or by direct ablation of tissues using electric fields. In addition, transfer of gene-based products into the cancer cells can be used for genetic vaccination to achieve systemic responses and cancer control. Readers will discover valuable reference texts for practitioner education, including chapters on electrodes for unique anatomical access and treatment planning for deep-seated tumors, different immunotherapy applications with gene electrotransfer, calcium electroporation, irreversible electroporation applications and combinations with other common treatments such as surgery, radiation therapy and chemotherapy.Therapy options with electroporation are gaining interest around the world in both human and veterinary oncology, making this book valuable for oncologists, surgeons, primary care veterinarians, residents, interns and students at veterinary schools, where teaching of Electrochemotherapy will become part of the curriculum.

Predator-Prey Interactions: Co-evolution between Bats and Their Prey (Paperback, 1st ed. 2016): David Steve Jacobs, Anna Bastian Predator-Prey Interactions: Co-evolution between Bats and Their Prey (Paperback, 1st ed. 2016)
David Steve Jacobs, Anna Bastian
R1,709 Discovery Miles 17 090 Ships in 10 - 15 working days

This book provides a comprehensive review of the evolution of traits associated with predation and predator defense for bats and all of their prey, both invertebrates (e.g. insects) and vertebrates (e.g. frogs), in the context of co-evolution. It reviews current knowledge of how echolocation and passive hearing are used by bats to hunt prey in complete darkness. Also it highlights how prey have evolved counter measures to bat echolocation to avoid detection and capture. This includes the whole range of prey responses from being active at times when bats are inactive to the use of acoustic signals of their own to interfere with the echolocation system of bats.

Digestive Physiology of Pigs (Hardcover): Jan Lindberg, Brian Ogle Digestive Physiology of Pigs (Hardcover)
Jan Lindberg, Brian Ogle
R3,919 Discovery Miles 39 190 Ships in 12 - 17 working days

This book brings together edited and revised papers presented at the 8th Symposium on Digestive Physiology of Pigs held in Uppsala in June, 2000. It contains more than 100 papers from leading scientists from around the world in this subject area. Among other features it contributes to the development of the the science relating to the effects of nutrition on gut physiology. It also creates a platform for future research, that will increase knowledge of how to optimize the nutrition of the pig and to help prevent diet-related gastrointestinal conditions.

Molecular Mechanisms for Sensory Signals - Recognition and Transformation (Paperback): Edward M. Kosower Molecular Mechanisms for Sensory Signals - Recognition and Transformation (Paperback)
Edward M. Kosower
R2,690 Discovery Miles 26 900 Ships in 10 - 15 working days

Pursuing the questions of how we learn and how memory is made, Edward Kosower introduces a novel and rich approach to connecting molecular properties with the biological properties that enable us to write and read, to create culture and ethics, and to think. Here he examines what happens within a single cell in reaction to external stimuli, and shows the parallels between single cell and multicellular responses. To address the problem of "learning," Kosower explains the molecular mechanisms of responses to input from taste, olfactory, and visual receptors. He then shows how these and other processes serve as the basis for memory. This study covers such signals for the molecular process of learning as pheromones (the molecular signals mediating behavior), light (activates the G-protein receptor, rhodopsin), and acetylcholine (opens the nicotinic acetylcholine receptor). Kosower's discussion of the structure and function of these complex molecules has direct implications for such areas as molecular neurobiology, bioorganic chemistry, and drug design, in elucidating approaches to the structure of drug targets. Originally published in 1991. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

The Teeth of Non-Mammalian Vertebrates (Hardcover): B. K. B Berkovitz, R. Peter Shellis The Teeth of Non-Mammalian Vertebrates (Hardcover)
B. K. B Berkovitz, R. Peter Shellis
R2,445 Discovery Miles 24 450 Ships in 12 - 17 working days

The Teeth of Non-Mammalian Vertebrates is the first comprehensive publication devoted to the teeth and dentitions of living fishes, amphibians and reptiles. The book presents a comprehensive survey of the amazing variety of tooth forms among non-mammalian vertebrates, based on descriptions of approximately 400 species belonging to about 160 families. The text is lavishly illustrated with more than 600 high-quality color and monochrome photographs of specimens gathered from top museums and research workers from around the world, supplemented by radiographs and micro-CT images. This stimulating work discusses the functional morphology of feeding, the attachment of teeth, and the relationship of tooth form to function, with each chapter accompanied by a comprehensive, up-to-date reference list. Following the descriptions of the teeth and dentitions in each class, four chapters review current topics with considerable research activity: tooth development; tooth replacement; and the structure, formation and evolution of the dental hard tissues. This timely book, authored by internationally recognized teachers and researchers in the field, also reflects the resurgence of interest in the dentitions of non-mammalian vertebrates as experimental systems to help understand genetic changes in evolution of teeth and jaws.

Ecological and Environmental Physiology of Mammals (Hardcover): Philip C. Withers, Christine E. Cooper, Shane K. Maloney,... Ecological and Environmental Physiology of Mammals (Hardcover)
Philip C. Withers, Christine E. Cooper, Shane K. Maloney, Francisco Bozinovic, Ariovaldo P. Cruz Neto
R4,147 Discovery Miles 41 470 Ships in 12 - 17 working days

Mammals are the so-called "pinnacle" group of vertebrates, successfully colonising virtually all terrestrial environments as well as the air (bats) and sea (especially pinnipeds and cetaceans). How mammals function and survive in these diverse environments has long fascinated mammologists, comparative physiologists and ecologists. Ecological and Environmental Physiology of Mammals explores the physiological mechanisms and evolutionary necessities that have made the spectacular adaptation of mammals possible. It summarises our current knowledge of the complex and sophisticated physiological approaches that mammals have for survival in a wide variety of ecological and environmental contexts: terrestrial, aerial, and aquatic. The authors have a strong comparative and quantitative focus in their broad approach to exploring mammal ecophysiology. As with other books in the Ecological and Environmental Physiology Series, the emphasis is on the unique physiological characteristics of mammals, their adaptations to extreme environments, and current experimental techniques and future research directions are also considered. This accessible text is suitable for graduate level students and researchers in the fields of mammalian comparative physiology and physiological ecology, including specialist courses in mammal ecology. It will also be of value and use to the many professional mammologists requiring a concise overview of the topic.

Progress in Mosquito Research, Volume 51 (Hardcover): Alexander S. Raikhel Progress in Mosquito Research, Volume 51 (Hardcover)
Alexander S. Raikhel
R3,561 Discovery Miles 35 610 Ships in 12 - 17 working days

Progress in Mosquito Research provides readers with the latest interdisciplinary reviews on the topic. It is an essential reference source for invertebrate physiologists, neurobiologists, entomologists, zoologists, and insect chemists, with Volume 51 focusing on recent progress in mosquito research.

Grass for Dairy Cattle (Hardcover): Jerome Cherney, Debbie Cherney Grass for Dairy Cattle (Hardcover)
Jerome Cherney, Debbie Cherney
R3,821 Discovery Miles 38 210 Ships in 12 - 17 working days

With the current interest in the environmental and economic sustainability of dairy farming, grass forage crops have emerged as a potential solution to some of the nutrient management problems now encountered on intensively managed dairy farms. The expansion and reintegration of grass-based systems into the mainstream of dairying systems will require a major paradigm shift involving economic, social and ecological, as well as biological factors. This book examines the role of grass in milk production in sustainable agricultural ecosystems. It provides a current summary of the role of grass in dairy cattle systems, including the breeding, management, storage, feeding and economics of grass for both lactating and dry dairy cows. Written by leading specialists from Australia, Europe, New Zealand, North and South America, this is an essential reference source for researchers, dairy industry professionals and advanced students of forage and dairy cattle nutrition.

The Indispensable Eight - The Birth and Rise of Kingdom Animalia (Paperback): Elena Elena Grigorieva, PhD The Indispensable Eight - The Birth and Rise of Kingdom Animalia (Paperback)
Elena Elena Grigorieva, PhD
R608 R531 Discovery Miles 5 310 Save R77 (13%) Ships in 10 - 15 working days
Pine Bark Beetles, Volume 50 (Hardcover): Claus Tittiger, Gary J. Blomquist Pine Bark Beetles, Volume 50 (Hardcover)
Claus Tittiger, Gary J. Blomquist
R3,548 Discovery Miles 35 480 Ships in 12 - 17 working days

Pine Bark Beetles, the latest release in the Advances in Insect Physiology series, provides readers with the latest interdisciplinary reviews on the topic. It is an essential reference source for invertebrate physiologists, neurobiologists, entomologists, zoologists, and insect chemists.

Energy Metabolism of Farm Animals (Hardcover): Kelvin McCracken, E. Unsworth, A. Wylie Energy Metabolism of Farm Animals (Hardcover)
Kelvin McCracken, E. Unsworth, A. Wylie
R3,982 Discovery Miles 39 820 Ships in 12 - 17 working days

The Proceedings of the 14th Symposium on Energy Metabolism of Farm Animals, held in Northern Ireland in September 1997, comprises 85 original contributions by leading scientists from over 20 countries around the world. In keeping with previous Symposia in the series, held under the auspices of the European Association for Animal Production, this book contains papers which provide the latest research on the energy metabolism and other aspects of the physiology of a wide variety of farmed animals. Highlights include a comprehensive review of the current state of research on leptins and their potential applications in animal production, and a large section relating to organ and tissue metabolism, with major contributions from the USA, UK, France, Germany and Denmark. An important strength of the book is the diversity of species covered. For example, the sections on modelling and feed evaluation relate to pigs, sows, broiler chickens, laying hens, turkeys, lambs, beef and dairy cattle and fish. There are also substantial contributions on lactation and reproduction, growth, environmental aspects and maintenance. This book is essential reading for research workers in animal science, particularly those concerned with nutrition and feed evaluation.

Animal Athletes - An Ecological and Evolutionary Approach (Paperback): Duncan J Irschick, Timothy E. Higham Animal Athletes - An Ecological and Evolutionary Approach (Paperback)
Duncan J Irschick, Timothy E. Higham
R1,606 Discovery Miles 16 060 Ships in 12 - 17 working days

Animals perform many athletic tasks to an amazing degree of accomplishment: not only spectacular feats of running and jumping but also routine actions that ensure survival such as feeding, vocalization, diving, flying, and many more. The study of performance capacity (defined as the ability of an animal to conduct a key task) is of great interest to both ecologists and evolutionary biologists. At an ecological level, how well individuals perform often dictates opportunities for reproduction, occupation of preferred territories, or capturing prey. Therefore, variation in performance capacities can be a key determinant of variation in fitness within animal populations. At an evolutionary level, variation in function often follows closely from variation in form, and therefore enables animals to invade novel habitats, or to overtake other species. This novel book examines how and why animal athletes have evolved. It uses examples from across the animal kingdom and integrates them in the broader context of ecology and evolution, thereby identifying common themes that transcend taxonomic divisions. Animal Athletes is an accessible textbook of particular relevance to undergraduates, graduate students, researchers, and professionals in the fields of evolutionary biology, ecology, vertebrate morphology, and functional morphology, and will also appeal to the interested layperson.

Physiology of Elasmobranch Fishes: Internal Processes, Volume 34B (Hardcover): Robert E. Shadwick, Anthony P. Farrell, Colin J.... Physiology of Elasmobranch Fishes: Internal Processes, Volume 34B (Hardcover)
Robert E. Shadwick, Anthony P. Farrell, Colin J. Brauner
R2,417 R2,165 Discovery Miles 21 650 Save R252 (10%) Ships in 12 - 17 working days

Fish Physiology: Physiology of Elasmobranch Fishes, Volume 34B is a useful reference for fish physiologists, biologists, ecologists, and conservation biologists. Following an increase in research on elasmobranchs due to the plight of sharks in today's oceans, this volume compares elasmobranchs to other groups of fish, highlights areas of interest for future research, and offers perspective on future problems. Covering measurements and lab-and-field based studies of large pelagic sharks, this volume is a natural addition to the renowned Fish Physiology series.

Physiology of Elasmobranch Fishes: Structure and Interaction with Environment, Volume 34A (Hardcover): Robert E. Shadwick,... Physiology of Elasmobranch Fishes: Structure and Interaction with Environment, Volume 34A (Hardcover)
Robert E. Shadwick, Anthony P. Farrell, Colin J. Brauner
R2,399 R2,268 Discovery Miles 22 680 Save R131 (5%) Ships in 12 - 17 working days

Fish Physiology: Physiology of Elasmobranch Fishes, Volume 34A is a useful reference for fish physiologists, biologists, ecologists, and conservation biologists. Following an increase in research on elasmobranchs due to the plight of sharks in today's oceans, this volume compares elasmobranchs to other groups of fish, highlights areas of interest for future research, and offers perspective on future problems. Covering measurements and lab-and-field based studies of large pelagic sharks, this volume is a natural addition to the renowned Fish Physiology series.

An Atlas of Comparative Vertebrate Histology (Hardcover): Donald McMillan, Richard James Harris An Atlas of Comparative Vertebrate Histology (Hardcover)
Donald McMillan, Richard James Harris
R3,468 R3,084 Discovery Miles 30 840 Save R384 (11%) Ships in 12 - 17 working days

Atlas of Comparative Vertebrate Histology looks at the histology of a wide range of vertebrates, representative of all the major classes and families, with examples ranging from amphioxus to primates. The authors focus their microscope on commonly seen vertebrates as well as 'non-standard' species, such as lamprey, hagfish, dogfish, skate, rock bass, cod, river catfish, toad, amphiuma, leopard and bull frog, garter and brown snake, Coturnix quail and cowbird. The study of comparative histology in the vertebrates helps students and researchers alike understand how various groups have addressed similar problems, opening doors to interesting research possibilities. Not all vertebrates follow the mammalian model of tissue and organ structure. When dealing with unique species, we see some structures taken beyond their 'normal' function. Comparative histology allows us to understand the structural responses underlying the physiology unique to each vertebrate group.

Trends in Veterinary Sciences - Current Aspects in Veterinary Morphophysiology, Biochemistry, Animal Production, Food Hygiene... Trends in Veterinary Sciences - Current Aspects in Veterinary Morphophysiology, Biochemistry, Animal Production, Food Hygiene and Clinical Sciences (Paperback, 2013 ed.)
Cristiano Boiti, Adriana Ferlazzo, Alberto Gaiti, Antonio Pugliese
R2,789 Discovery Miles 27 890 Ships in 10 - 15 working days

Veterinary science is continuously achieving important developments in all its fields as a result of continuous technological advances in diagnostic tools and applied biology. This book contains 33 papers that were selected from those presented at the 65th Congress of the Italian Society for Veterinary Sciences held at Tropea-Drapia in 2011. It provides a timely overview of the current progress being made by Italian researchers and is of great value to anyone interested in all fields of veterinary science, both theoretical and applied, ranging from animal health and care to animal production and food hygiene.

Mathematical Modeling in Renal Physiology (Paperback, 2013): Anita T. Layton, Aurelie Edwards Mathematical Modeling in Renal Physiology (Paperback, 2013)
Anita T. Layton, Aurelie Edwards
R2,491 Discovery Miles 24 910 Ships in 10 - 15 working days

With the availability of high speed computers and advances in computational techniques, the application of mathematical modeling to biological systems is expanding. This comprehensive and richly illustrated volume provides up-to-date, wide-ranging material on the mathematical modeling of kidney physiology, including clinical data analysis and practice exercises. Basic concepts and modeling techniques introduced in this volume can be applied to other areas (or organs) of physiology.

The models presented describe the main homeostatic functions performed by the kidney, including blood filtration, excretion of water and salt, maintenance of electrolyte balance and regulation of blood pressure. Each chapter includes an introduction to the basic relevant physiology, a derivation of the essential conservation equations and then a discussion of a series of mathematical models, with increasing level of complexity.

This volume will be of interest to biological and mathematical scientists, as well as physiologists and nephrologists, who would like an introduction to mathematical techniques that can be applied to renal transport and function. The material is written for students who have had college-level calculus, but can be used in modeling courses in applied mathematics at all levels through early graduate courses.

Growth of Farm Animals (Hardcover, 3rd edition): Tony Lawrence, Vernon Fowler, Jan Novakofski Growth of Farm Animals (Hardcover, 3rd edition)
Tony Lawrence, Vernon Fowler, Jan Novakofski
R3,835 Discovery Miles 38 350 Ships in 12 - 17 working days

Understanding the processes that change the shape and composition of farm animals is fundamental to all aspects of production. Showing the progression from cell to tissue to entire animal, this comprehensive textbook provides an essential broad base for animal production, with key information on how animals grow and change in shape and composition, and factors that affect these processes. Illustrated with new photographs and focus boxes highlighting vital points, this updated third edition includes a new chapter on avian growth, an important source of protein for the expanding population. Providing a thorough yet student-friendly approach to the subject, this book continues to fill the important role of helping readers to understand how the basics of growth must be thoroughly understood if farm animals are to be used efficiently and humanely in producing food for mankind.

Biology and Physiology of the Blood-Brain Barrier - Transport, Cellular Interactions, and Brain Pathologies (Paperback,... Biology and Physiology of the Blood-Brain Barrier - Transport, Cellular Interactions, and Brain Pathologies (Paperback, Softcover reprint of the original 1st ed. 1996)
Pierre-Olivier Couraud, Daniel Scherman
R5,489 Discovery Miles 54 890 Ships in 10 - 15 working days

The endothelial cells of the cerebral vasculature constitute, together with perivascular elements (astrocytes, pcricytes, basement membrane), the blood-brain barrier (BBB), which strictly limits and specifically controls the exchanges between the blood and the cerebral extracellular spacc.The existence of such a physical, enzymatic, and active barrier isolating the central nervous system has broad physiological, biological, pharmacological, and patho logical consequences, most of which are not yet fully elucidated. The Cerebral Vascular Biology conference (CVB '95) was organized and held at the "Carre des Sciences" in Paris on July I 0-12, 1995. Like the CVB '92 conference held in Duluth, Minnesota, three years ago, the objectives were to provide a forum for presentation of the most recent progresses and to stimulate discussions in the ticld of the biology, physiology. and pathology of the blood-brain barrier. The Paris conference gathered more than 50 participants. including investigators in basic neuroscience, physicians. and stu dents, who actively contributed to the scientific program by their oral or poster presentations. This volume contains a collection of short articles that summarize most of the new data that were presented at the conference. Six thematic parts focus on physiological transports. drug delivery, multidrug resistance P-glycoprotein, signal transduction at the BBB. interactions between the immune system and the cerebral endothelial cells, and the blood-brain barrier-related pathologies in the central nervous system. In addition, two introductory articles present new insights in the rapidly evolving topics of cerebral angiogenesis and gene transfer to the brain."

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