This book represents Part 2 of a venture started by distinguished neuroscientists to visualize and advertise the experimentally advantageous preparations of the crustacean nervous system. The advantage is a combination of ease of dissection of key structures and the possibility of repeatedly accessing identified individual cells to measure the detailed response of the system to the experimentally imposed stimulus program. Of course, the neurosciences have to focus their research on the nervous system of mammals and man in order to understand the principles of function and their regulation if malfunctions occur. This is in line with efforts to investigate nervous systems throughout the animal kingdom. The specific potential of the encountered systems for exploratory research into hitherto unexplained functions of the brain may very well be a key to new insights. The simply organized nervous system of crustaceans performs tasks of vital importance imposed on the organism. Hence this system consists of a complete set of neural circuitry open for inspection and measurement by systematic investigation. The first volume, The Crustacean Nervous System, contains exhaustive reports on experimental work from all sectors of neuroscience using crayfish and lobsters. This second volume, Crustacean Experimental Systems in Neurobiology," contains excellent reviews on significant topics in neurobiology. Each section is introduced by short texts written by the section editors of the Crustacean Nervous System. More, prominent authors explain their approach to understanding the brain using a selection of experiments involving visual orientation, neuromuscular systems and identification of principles of neural processing.

The origins of what have come to be known as the "Oxford" Conferences on modelling and the control of breathing can be traced back to a discussion between Dan Cunningham and Richard Hercynski at a conference dinner at the Polish Academy of Sciences in 1971. Each felt that they had benefited from the different perspectives from which the topic of ventilatory control was approached - predominantly physiological in the case of Dr Cunningham and predominantly mathematical in the case of Dr Hercynski. Their judgement at that time was that a conference on the control of breathing which allowed investigators with these different (but related) scientific perspectives to present and discuss their work, might prove fruitful. We would judge that this has amply been borne out, based upon the success of the series of conferences which resulted from that seminal dinner conversation. The first conference, entitled "Modelling of a Biological Control System: The Regulation of Breathing" was held in Oxford, UK, in 1978. Subsequent conferences were: "Modelling and the Control of Breathing" at Lake Arrowhead, California, in 1982; "Con cepts and Formulations in the Control of Breathing" in Solignac, France, in 1985; "Respi ratory Control: A Modeling Perspective" at Grand Lakes, Colorado, in 1988; and "Control of Breathing and Its Modelling Persepctive" at the Fuji Institute in Japan in 1991. The conferences, subsequent to the one in Oxford, have all resulted in well-received published proceedings.

A review of our understanding of this area of the brain, showing how it fits into the general picture of those areas concerned with modulating mammalian behavior. The chapters, all written by leading figures in behavioral neuroscience, discuss the anatomy, neurochemistry, physiology, and behavioral relations in the septal area. Due to the great deal of current research shown in the related areas of hippocampus and the amygdala, this book will be of great interest to all those who research the hippocampus and the amygdala in addition to the septum itself.

This is the third meeting we have organized which has explored the meaning of fetal neural developmental disruption in the etiology of schiwphrenia. The first was sponsored by the Schiwphrenia Research Branch with the scientific cooperation of Dr. David Shore. We met in Washington; the output of the meeting was published in a book entitled, Fetal Neural Development and Adult Schizophrenia. Cambridge University Press. 1991. The next meeting was an Advanced Research Workshop sponsored by NATO and was held at n Ciocco. Castelvecchio Pascoli. This meeting was reported in a NATO volume. Developmental Neuropathology of Schizophrenia and was edited by Mednick. Cannon. Barr and La Fosse. The current meeting has noted several advances in the field. There are additional psychiatric illnesses which have been found to be related to maternal viral infection in the second trimester. There have been studies reported which have definitely observed a viral infection in the mothers of fetuses who later evidenced schirophrenia. More evidence has been published which has replicated the "second-trimester effect." In the future studies will be wise to provide serological evidence of a viral infection and information on the precise viruses involved. Another important step will be to determine whether second-trimester maternal viral infection is related to a behavioral deficit in the infant. If neural development has been compromised. it might be possible to detect deficits in the infant with the proper measures. We look forward to future meetings at which these new areas might be explored.

The NATO Advanced Research Workshop entitled "The Photosynthetic Bacterial Reaction Center: Structure, Spectroscopy, and Dynamics" was held May 10-15, 1992, in the Maison d'H6tes of the Centre d'Etudes Nuc1eaires de Cadarache near Aix-en-Provence in the south of France. This workshop is the most recent of a string of meetings which started in Feldafing (Germany) in March 1985, soon after the three-dimensional structure of the bacterial reaction center had been elucidated by X-ray crystallography. This was followed, in September 1987, by a workshop in Cadarache and, in March 1990, by a second meeting in Feldafing. Although one of the most important processes on Earth, photosynthesis is still poorly understood. Stimulated by the breakthrough of solving the bacterial reaction center structure at atomic resolution, the field of relating this structure to the function of the reaction center, i. e. the remarkably efficient conversion and storage of solar energy, has been developing vigorously. Once the general organization of the cofactors and some details of the protein-cofactor interactions were known, it became possible to combine a variety of spectroscopic techniques with the powerful tool of site-directed mutagenesis in order to address increasingly incisive questions about the specific role of some amino acid residues in the electron transfer process. Still another promising tool is being developed, namely the exchange of a number of the native bacteriochlorophyll and bacteriopheophytin cofactors by chemically modified pigments.

Intraspecific communication involves the activation of chemoreceptors and subsequent activation of different central areas that coordinate the responses of the entire organism-ranging from behavioral modification to modulation of hormones release. Animals emit intraspecific chemical signals, often referred to as pheromones, to advertise their presence to members of the same species and to regulate interactions aimed at establishing and regulating social and reproductive bonds. In the last two decades, scientists have developed a greater understanding of the neural processing of these chemical signals. Neurobiology of Chemical Communication explores the role of the chemical senses in mediating intraspecific communication. Providing an up-to-date outline of the most recent advances in the field, it presents data from laboratory and wild species, ranging from invertebrates to vertebrates, from insects to humans. The book examines the structure, anatomy, electrophysiology, and molecular biology of pheromones. It discusses how chemical signals work on different mammalian and non-mammalian species and includes chapters on insects, Drosophila, honey bees, amphibians, mice, tigers, and cattle. It also explores the controversial topic of human pheromones. An essential reference for students and researchers in the field of pheromones, this is also an ideal resource for those working on behavioral phenotyping of animal models and persons interested in the biology/ecology of wild and domestic species.

Animals and plants live in changing environmental conditions which require adaptation in order to cope with this. Some of these environmental changes serve as signals which have to be "sensed" and interpreted correctly by the organisms to initiate the adaptation. This signal processing is based on biochemical, molecular and neuronal processes which are discussed in this book. All examples given underline that continuous adjustment of physiological functions is an essential requirement for life and survival in complex changing environments.

Comparative Vertebrate Reproduction is the only comprehensive textbook covering major topics in the reproductive biology of vertebrates, from sexuality and gametogenesis to reproductive ecology and life history tactics. The work draws heavily on recent reviews and papers while placing topics in a historical context and conceptual framework. In addition, the author provides detailed comparative surveys of each of the major topics discussed. Comparative Vertebrate Reproduction has been written as a textbook for upper-level undergraduate and graduate-level students in biology, zoology, physiology, animal science, and veterinary medicine. The work also serves as an excellent reference for researchers in medical and veterinary schools working in reproductive medicine.

This book describes in general how the chemosensory systems of fish function at various levels. In many ways, fish are typical vertebrates differing only slightly from other vertebrates including humans. In other ways, their aquatic environment imposes strict requirements or offers unique opportunities which have resulted in some unusual functions having no counterpart in higher vertebrates. This new volume is necessitated by advances in many vital areas as the field of chemical senses continues to grow at a rapid pace. Most significant is the application of the contemporary electrophysiological technique of patch-clamping, recognition of a second messenger system in chemosensory transduction processes and the identification of hormonal pheromones in fish reproductive behaviour. The last major synthesis of our knowledge about fish chemoreception, Chemoreception in Fishes, was published ten years ago (Elsevier, Amsterdam, 1982). In that volume four aspects of fish chemoreception, Le. morphology of the peripheral chemoreceptors. primary sensory processes, roles in behaviour, and its interactions with environment, were discussed. This book is intended to be helpful to students, scientists and aquacul turists not only as a source book but also as a textbook on chemical senses."

Among the fishes, a remarkably wide range of biological adaptations to diverse habitats has evolved. As well as living in the conventional habitats of lakes, ponds, rivers, rock pools and the open sea, fish have solved the problems of life in deserts, in the deep sea, in the cold antarctic, and in warm waters of high alkalinity or of low oxygen. Along with these adaptations, we find the most impressive specializations of morphology, physiology and behaviour. For example we can marvel at the high-speed swimming of the marlins, sailfish and warm-blooded tunas, air-breathing in catfish and lung fish, parental care in the mouth-brooding cichlids and viviparity in many sharks and toothcarps. Moreover, fish are of considerable importance to the survival of the human species in the form of nutritious, delicious and diverse food. Rational exploitation and management of our global stocks of fishes must rely upon a detailed and precise insight of their biology. The Chapman & Hall Fish and Fisheries Series aims to present timely volumes reviewing important aspects of fish biology. Most volumes will be of interest to research workers in biology, zoology, ecology and physiology but an additional aim is for the books to be accessible to a wide spectrum of non-specialist readers ranging from undergraduates and postgraduates to those with an intrerest in industrial and commercial aspects of fish and fisheries."

This timely volume presents a comprehensive overview of the behavioral and physiological mechanisms underlying insect feeding. The single source for up-to-date information on the subject, it features contributions from the most authoritative scientists in the field worldwide. Taking an accessible approach focusing on the sequential stages of the feeding process, Regulatory Mechanisms in Insect Feeding explores the principles regulating feeding, and it offers information necessary for the development of more effective and environmentally safe methods to control the feeding of pest insects. The authors incorporate a spectrum of information in areas ranging from neurophysiology to insect control.An inclusive reference that reflects recent expansion and advances in the field, this book * considers the problems encountered by insects when feeding on different types of food, as well as their adaptations for dealing with the problems * introduces the cyclic nature of feeding activity and its components and provides the framework for the discussion of various control mechanisms * discusses the underlying regulatory mechanisms of feeding in both the short and long terms in insects with a diversity of feeding habits * synthesizes concepts and details of the basic mechanisms underlying insect feeding behavior that are essential for the development of pest management methods. Regulatory Mechanisms in Insect Feeding is the ideal text for graduate courses in entomology and zoology with a special focus on insect behavior, physiology, neurobiology, and control. It is also a valuable resource for ecologists interested in insect-plant and insect-animal interactions, for scientists concerned with the mechanisms behind the physiology and behavior of feeding, and for those working in crop protection and pest management.

The Handbook of Behavioral Neurobiology series deals with the aspects of neurosciences that have the most direct and immediate bearing on behavior. It presents the most current research available in the specific areas of sensory modalities. This volume explores circadian rhythms.

In six parts, this book considers the extent to which computational, neural, and ecological constraints have shaped the mechanisms underlying motion vision: - Early Motion Vision - Motion Signals for Local and Global Analysis - Optical Flow Patterns - Motion Vision in Action - Neural Coding of Motion - Motion in Natural Environments Each topic is introduced by a keynote chapter which is accompanied by several companion articles. Written by an international group of experts in neurobiology, psychophysics, animal behaviour, machine vision, and robotics, the book is designed to explore as comprehensively as possible the present state of knowledge concerning the principal factors that have guided the evolution of motion vision.

It is generally accepted that the recent progress in molecular and cellular biology would not have been possible without an understanding of the mechanisms and signaling pathways of communication inside the cell and between various cells of the animal organism. In fact a similar progress occurred in the field of chemical communication between individual organisms of vertebrate species, and this volume is aimed at presenting the current state of the art on this subject. The reader can find here both original results obtained in the laboratory or field studies and comprehensive reviews summarizing many years of research. The presentations of over 60 scientists have been grouped according to their approach into nine parts covering such fields as ecological and evolutionary aspects of chemical communication, structure and neuronal mechanisms of chemosensory systems, chemical structure of pheromones and binding proteins, kin, individual and sexual recognition, predator-prey relationships, purpose and consequences of marking behavior, scent signals and reproductive processes. Expanding on former volumes of this series, entirely new chapters have been added on prenatal chemical communication describing specific effects of the intrauterine environment. In many cases a truly multidisciplinary approach was required, such as with the population analysis of polymorphic variants of the mouse's major urinary proteins that function in carrying pheromones.

A presentation of the most elementary form of pulsatile flow as an important prerequisite for the study of other flow applications in biological systems. The book provides in a single source a complete treatment of the fluid dynamics of flow with the required mathematics and emphasis on the basis mechanics. The style and level of this book make it accessible to students and researchers in biophysics, biology, medicine, bioengineering and applied mathematics working in theoretical and clinical work on the cardiovascular system, as well as in the design of new instrumentation, medical imaging systems, and artificial organs. With problems and exercises.

Aquaculture is now recognized as a viable and profitable enterprise worldwide. As aquaculture technology has evolved, the push toward higher yields and faster growth has involved the enhancement or replacement of natural foods with prepared diets. In many aquaculture operations today, feed accounts for more than one-half the variable operating cost. Therefore, knowledge of nutrition and practical feeding of fish is essential to successful aquaculture. This book is not written exclusively for scientists but also for students, practicing nutritionists, and aquaculturists. It covers the known nutrient requirements and deficiency effects for different fishes, and digestion and metabolism of nutrients and energy. It discusses nutrient sources and preparation of practical and research feeds. It gives directions for conducting fish nutrition and feeding experiments. Feeding practices for salmonids, channel catfish, tilapias, shrimps and hybrid striped bass are presented. Since the first edition of this book was printed, the National Research Council of the National Academy of Sciences has revised the nutrient requirements for fish. These revisions are in the present edition. Other additions to this revised edition are chapters on nutrition and fish health, and bioavailability of nutrients. Each original chapter has been meticulously revised and updated with new information. Aquaculture is a dynamic area and new technologies are being introduced continuously; therefore, some of the material discussed in this revised edition may become obsolete quickly. Nonetheless, the material presented has been thoughtfully selected and updated to make it of maximum use to persons whose interests range from general aquaculture to animal nutrition to feed manufacture.

Extremely diverse and complicated bacterial and protozoan populations inhabit the rumen and intestinal tract of animals, and there is a delicate balance among the individual populations within this complex microbial community. This authoritative edited volume, the first in a two-volume set, reviews the gut environment and the fermentations taking place in animal digestive tracts. It is an essential source of reference for microbial ecologists and physiologists, medical microbiologists and gastroenterologists, biochemists, nutritionists, veterinarians and animal scientists, and wildlife ecologists.

Photobiology - the science of light and life - begins with basic principles and the physics of light and continues with general photobiological research methods, such as generation of light, measurement of light, and action spectroscopy. In an interdisciplinary way, it then treats how organisms tune their pigments and structures to the wavelength components of light, and how light is registered by organisms. Then follow various examples of photobiological phenomena: the design of the compound eye in relation to the properties of light, phototoxicity, photobiology of the human skin and of vitamin D, photomorphogenesis, photoperiodism, the setting of the biological clock by light, and bioluminescence. A final chapter is devoted to teaching experiments and demonstrations in photobiology.
This book encompasses topics from a diverse array of traditional disciplines: physics, biochemistry, medicine, zoology, botany, microbiology, etc., and makes different aspects of photobiology accessible to experts in all these areas as well as to the novice. It is intended primarily for graduate students and for researchers who wish to look outside their speciality, but can also act as a source of information for undergraduate students.

The International Society for Arterial Chemoreception (ISAC) was founded in August 1988 during the 9th International Symposium on Arterial Chemoreception which was held at Park City, Utah, USA. ISAC was established with the aim of providing a framework to support the increasing number of investigators from a wide variety of disciplines (anatomists, pathologists, respiratory physiologists and clinicians, high altitude physiologists, biochemists, biophysicists, physiologists and pharmacologists) who share a common interest in arterial chemoreception. ISAC took over the co-ordination of the international chemoreceptor meetings, with the membership deciding the venue for forthcoming meetings. During the Park City symposium Dublin was selected to host the 1993 meeting, under the Presidency of Professor Ronan O'Regan. The 12th International Meeting on Arterial Chemoreception, which was held in Dublin in August 1993, was acclaimed as a great success by all those present. The delegates not only shared in a wide-ranging feast of chemoreceptor based science, they had plenty of opportunity during the meeting for renewing acquaintances and establishing new friendships. The location for the meeting at University College Dublin's modem Belfield campus helped to promote such interaction, and the social programme was outstanding.

The Third International Symposium on Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle, organized by George Frank, C. Paul Bianchi, and Henk E. DJ. ter Keurs, was held in Banff Centre, Banff, Alberta, Canada during June 26 to June 30, 1991. The theme of these symposia has been to recognize the similarities and dissimilarities of excitation-contraction coupling in skeletal, cardiac, and smooth muscle. Cross fertilization of concepts of excitation-contraction coupling in these three types of muscle has occurred since the early studies in the late fifties and early sixties on skeletal muscle. Investigators in each field meet only at specialized symposia which exclude investigators in the other fields. The purpose of the symposia has been to bring together international investigators studying excitation-contraction coupling in skeletal, cardiac, and smooth muscle so that we may learn from each other and hence provide a more global concept of excitation-contraction. The Third International Symposia has accomplished its objective as we recognize that calcium channels of the sarcolemma and the sarcoplasmic reticulum play key essential roles in excitation-contraction coupling in all three types of muscles. In skeletal muscle the recognition that E-C coupling consists of two parallel mechanisms, one dependent upon a dihydropyridine voltage-sensitive sensors coupled to calcium release from the terminal cisternae via the ryanodine sensitive channel in the foot structure of the triad.

This monograph evolved from years of research into the auditory pathway and hearing of many species of marsupials. Its function is to give biologists, in par ticular neurobiologists, a broad description and review of what is known of the auditory sensory capacities and processing mechanisms in this large order of mammals. My initial interest in marsupials developed from collaborative work with Dr. Richard Gates at Monash and Melbourne Universities in the 1970s and by curiosity as to whether concepts about the auditory system was stimulated stemming from experiments mainly on domestic cats could be extended to mam mals of other orders. My subsequent interest in Australian marsupials, aroused by collaboration with Dr. John Nelson at Monash University in the 1980s and 1990s, concerned their auditory systems and behavior per se and not as primitive cousins of eutherians. More recently, I have collaborated with Dr. Bruce Masterton at Florida State University in studies of New World marsupials. His sad death in 1996 has robbed neurobiologists of one of our most provocative thinkers and hypothesis testers. I would like to thank the Department of Physiology at Monash University for making many facilities available to me, the National Health and Medical Research of Australia and the Australian Research Council for providing funds for Council research, and Jill Poynton and Michelle Mulholland, who illustrated this volume."

Acute lung injury, respiratory failure, and acute respiratorydistresssyndrome associ- ated with sepsis and multiorgan dysfunction isbecoming more common in hospitals through- out the world. Although new classesofantimicrobial medications have been introduced and aggressive intensive life support systems are in use in many hospitals, mortality remains in the range of35 to 65 percent in even the best equipped medical facilities. However, with new technologies inphysiology and cellularand molecularbiology, wonderful opportunities now exist for scientists to explore more effective approaches to identificationofpatients at risk, to develop better insights to pathogenic mechanisms, to use new tools to follow the progression and natural history ofdisease, and to develop better modes oftherapies. The NATOAdvanced Study Institute on Acute RespiratoryDistress Syndrome: Cel- lularandMolecularMechanisms and ClinicalManagement was an outstanding opportunity for laboratory scientists and clinical investigators to discuss their own research approaches, explore opportunities for bringing newdimensions to their laboratories, and work together to identify possible clinical applications. The conference brought together investigators who have worked with patients ofall ages, including those who have so successfully treated in- fants with respiratory distress syndrome. There is no doubt that this stimulating conference will bring new dimensions, new technologies, and new investigators into the scientific labo- ratoriesofeach participant. This provides hope that new therapeutic approaches will eventu- ally be available.

Over the course of the past decade, there has been an enormous augmentation in the amount of information available on the lemurs of Madagascar. These advances are closely coupled with an increase in the number of national and international researchers working on these animals. As a result, Madagascar has emerged as one of the principal sites of primatological studies in the world. Furthermore, the conserva tion community has a massive interest in the preservation of the natural habitats of the island, and lemurs serve as one of the symbols of this cause. Between 10 and 14 August 1998, the XVIIth International Primatology Society (IPS) Congress was held in Antananarivo, Madagascar. For a country that about a decade ago was largely closed to foreign visitors, this Congress constituted a massive event for the Malagasy scientific community and was assisted by about 550 primatolo gists from 35 different countries. Naturally, given the venue and context of the Con gress, many of the presentations dealt with lemurs and covered a very wide breadth of subjects.