The first in the Problems in Anesthesia seris, Cardiothoracic Surgery examine and provide guidance for a number of problematic clinical scenarios in cardiothoracic surgery anesthesia. This is a field which is growing in complexity due to the increasingly diverse set of conditions that are now treated surgically, and also due to developments in technology which are leading to different approaches to even common problems. This book will be of interest to the qualified specialist and the general trainee in anesthesiology.

Cases are presented followed by an approach to the case, utilizing the various experiences of anesthesiologists from both sides of the Atlantic. The case-based teaching relates the material to the clinic, and the discussion then explains the options in approach. Each chapter concludes with a series of essential tips in dealing with the various problems. Cases covered range from the common (e.g. off-pump coronary bypass) to the rare (e.g. anesthetic management of the patient with carcinoid heart disease).

The aim of the book is to allow readers to learn from both the successes and the complications within the cases covered, and in this way disseminate knowledge amongst those working in the field as well as pave the way for further investigation and continued advancement.

SHORTLISTED FOR THE COSTA BIOGRAPHY PRIZE THE SUNDAY TIMES NO.2 BESTSELLER WINNER OF THE BMA PRESIDENT'S AWARD 2017 An incredible memoir from one of the world's most eminent heart surgeons, recalling some of the most remarkable and poignant cases he's worked on. Grim Reaper sits on the heart surgeon's shoulder. A slip of the hand and life ebbs away. The balance between life and death is so delicate, and the heart surgeon walks that rope between the two. In the operating room there is no time for doubt. It is flesh, blood, rib-retractors and pumping the vital organ with your bare hand to squeeze the life back into it. An off-day can have dire consequences - this job has a steep learning curve, and the cost is measured in human life. Cardiac surgery is not for the faint of heart. Professor Stephen Westaby took chances and pushed the boundaries of heart surgery. He saved hundreds of lives over the course of a thirty-five year career and now, in his astounding memoir, Westaby details some of his most remarkable and poignant cases - such as the baby who had suffered multiple heart attacks by six months old, a woman who lived the nightmare of locked-in syndrome, and a man whose life was powered by a battery for eight years. A powerful, important and incredibly moving book, Fragile Lives offers an exceptional insight into the exhilarating and sometimes tragic world of heart surgery, and how it feels to hold someone's life in your hands.

This book provides a comprehensive introduction to artificial hearts, summarizing the latest advances in basic technologies, design, evaluation, and management. Featuring 11 chapters, it discusses the origins of the artificial heart, the mechanisms of heart failure, and the principles of artificial heart technologies. Further, it offers an overview of rotary pumps and volume-displacement pumps, and addresses total artificial hearts. Lastly, the book covers evaluation, selection, therapy management, challenges, and the latest innovations. Given its scope, it is a valuable resource for researchers and technicians in the area of biomedical engineering, as well as surgeons.

This text, published in the profession's centenary year, traces the history of cardiac surgery from ancient times to the present, detailing clinical developments with facsimilies of the original articles, consent forms from the first heart transplant, newspaper articles, and correspondence. The text follows a set pattern, describing the historical background to each new procedure, facsimilies of the original articles, bibliography of the main clinicians, and a commentary putting each development into its historical context.

This book provides an overview of the etiology of coronary artery disease and focuses on the main therapies and drug interventions currently available. It highlights drug pharmacology and therapeutic challenges, with a special emphasis on the underlying principles of available therapeutics and the on-going development of drugs for coronary artery disease. The book is divided into eight chapters, the first of which describes the classical mechanism of coronary artery disease and its clinical presentations. Chapter 2 lists the principles of and related evidence on the prevention and treatment of coronary artery disease. This includes diet and lifestyle management, and guidelines for the treatment of acute coronary syndrome and stable coronary artery disease. In turn, Chapter 3 describes revascularization treatments, covering percutaneous coronary interventions, coronary artery bypass grafts and thrombolysis. This chapter also addresses the main therapeutic challenges. The following chapters provide an overview of three major categories of coronary artery disease drugs, which target thrombosis (Chapter 4), lipid metabolism (Chapter 5), and hypertension (Chapter 6). Heart failure constitutes the major health burden in the late stage of coronary artery disease; accordingly, current heart failure therapeutics and related drug pharmacology are described in Chapter 7. In closing, Chapter 8 provides a summary of on-going clinical trials for coronary artery disease drug development and discusses a number of promising areas in which intensive research into new therapeutics is being pursued. Given its scope, the book will be of interest to clinicians, medical students and research scientists, as well as to pharmaceutical professionals who are seeking new therapies and drugs for coronary artery disease and related disorders.

The recent widespread application of minimally invasive techniques has had a profound impact on the diagnosis and therapy of thoracic disorders, including in the pediatric age group. This book is intended as a practical guide to the current approaches in pediatric thoracic surgery. Up-to-date information is provided on the surgical techniques employed for diagnosis and therapy in a wide range of congenital and acquired thoracic pathologies from the prenatal age to adolescence. Among the disorders considered in detail are cystic malformations of the lung, chest wall deformities, diaphragmatic hernias, esophageal anomalies, mediastinal tumors, laryngeal anomalies, and thoracic infections. The authors are distinguished experts in the field from across the world. "Pediatric Thoracic Surgery" will be of value not only for pediatric thoracic surgeons but also for adult thoracic surgeons, pediatric anesthetists, and pediatric respiratory physicians.

Although cardiac surgery has made an enormous progress during the last decades, the discipline has to cope with essential changes: Patients are increasingly cared for by cardiologists and therefore referred to the surgeon in a later stage of disease. Consequently, they are more often in an increasingly serious state or in advanced age with significant comorbidities.

In order to meet the requirements of these different patient groups, cardiosurgical treatments require special protectional strategies for the heart in order to perform the planned operations safely. This book presents the latest knowledge of modern techniques of myocardial protection taking into consideration the different patient groups and current scientific strategies. Furthermore, it discusses present and future scientific approaches in myocardial protection and preservation.

50 Studies every Vascular Surgeon Should Know presents key studies that have shaped the practice of Vascular Surgery. Selected using a rigorous methodology, the studies cover topics including carotid artery disease, aortic aneurysm, peripheral artery disease, trauma, venous disease and vascular access. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implication for practice. An illustrative clinical case concludes each review to highlight the impact of the study on clinical practice. This book is a must read for vascular surgeons, especially those in training and preparing for board exams, as well as anyone who wants to learn more about the data behind clinical practice.

This new edition of the bestselling step-by-step introduction to cardiac pacemakers now includes additional material on CRT and an accompanying website. It retains the effective use of full-page illustrations and short explanations that gained the book such enormous popularity and now provides information on recent advances in cardiac pacing, including biventricular pacing for the treatment of heart failure.

This comprehensive resource brings together the most current theories, evidence and best practice parameters for the use of nocturnal non-invasive ventilation (nNIV). Chapters focus on the application of acute and chronic nNIV in patients with cardio-respiratory disorders over a range of major medical settings. Updates on past and recent research in this field are highlighted. Authored by leading clinicians and investigators, Nocturnal Non-Invasive Ventilation provides practical and cutting-edge knowledge to physicians, researchers and allied health professionals on the front lines of treating cardio-respiratory and sleep disorders.

This book on cardiac extracellular matrix (ECM) features three sections, Fundamental Science, Pre-Clinical and Translational Science, and Clinical Applications. In the Fundamental Science section, we will cover the spectrum of basic ECM science from ECM's role in development, biomechanical properties, cardiac ECM influence of cardiomyocyte biology, pathophysiology of ECM in heart disease, and ECM in tissue engineering. Section two, Preclinical and Translational Science, will discuss cardiac ECM technologies in the clinical pipeline including approaches to ECM as a therapeutic, animal models of cardiac research, tracking and imaging methods of cardiac ECM, and cGMP manufacturing and regulatory considerations for ECM based therapeutics. Finally, the third section, Clinical Applications, will highlight the clinical experience around cardiac ECM including therapeutic strategies targeting scar tissue in the heart, Clinical trial design and regulatory considerations, current human clinical trials in cardiovascular medicine and the role of pharmaceutical and biotech companies in the commercialization of ECM technologies for cardiovascular indications. This book provides a comprehensive review for basic and translational researchers as well as clinical practitioners and those involved in commercialization, regulatory and entrepreneurial activities.

This issue of Thoracic Surgery Clinics of North America, guest edited by Drs. Inderpal S. Sarkaria and Abbas E. Abbas, is devoted to Paraesophageal Hernia Repair. Drs. Sarkaria and Abbas has assembled expert authors to review the following topics: Management of Complications in Paraesophageal Hernia Repair; Surgical Anatomy of Paraesophageal Hernias; Robotic Paraesophageal Hernia Repair; Management of Paraesophageal Hernia in the Obese Patient; Technical Options and Approaches to Lengthen the Shortened Esophagus; Laparoscopic Paraesophageal Hernia Repair; Short and Long Term Outcomes of Paraesophageal Hernia Repair; Pre-operative Evaluation and Clinical Decision Making for Giant Paraesophageal Hernias: Who Gets an Operation?; Common Tenets in Repair of Primary Paraesophageal Hernias: Reducing Tension and Maximizing Length; Management of Recurrent Paraesophageal Hernia; Transthoracic Paraesophageal Hernia Repair; Anesthetic Management for Paraesophageal Hernia Repair; and more!

This issue of Thoracic Surgery Clinics of North America, guest edited by Dr. Edward D. Verrier, is devoted to Education and the Thoracic Surgeon. Dr. Verrier has assembled expert authors to review the following topics: The Master surgeon as educator; How does the adult surgeon learn?; How to obtain meaningful assessment in thoracic surgery education; How to give effective formative feedback in thoracic surgery education; Bias: How to minimize the hidden impact on thoracic surgical education; The educational challenges of the operating room; Effective classroom teaching and the impact of e-learning in thoracic surgery education; The alternative surgical curriculum; Deliberate practice and the emerging roles of simulation in thoracic surgery; Teaching, mentorship, and coaching in thoracic surgical education; Faculty development: using education for career advancement; The potential of virtual or augmented reality to enhance thoracic surgical education; How will artificial intelligence impact (cognitive) decision making in thoracic surgery; and more!

Cardiothoracic nursing has undergone great change over the last decade. With the continuing improvement of surgical techniques, pharmacology and pre- and post-operative care, there have been many new initiatives and innovations in the nature and practice of this specialised sector of nursing. Rehabilitation and patient education are to name but a few of the areas where exciting new challenges and opportunities for cardiothoracic nurses have opened up.

This book is a definitive and accessible text for cardiothoracic nurses. Written for nurses from a nursing perspective, it offers practical advice and information on all aspects of cardiothoracic surgical nursing and pays particular attention to the continuing developments cardiothoracic nurses must face.
An essential reference book for all those practising or studying in this area
Offers advice and information to help ensure the best quality of care is offered to patients undergoing cardiothoracic surgery
Explores new models of nursing practice
Detailed references and further reading

This book presents the most recent developments in oncologic breast surgery and takes full account of diagnostic, pathologic, and radiologic inputs. It is divided into three parts, the first of which discusses the premises underlying the modern surgical approach to breast cancer. The second part is devoted to what might be termed the conservative program, i.e., breast conservation and oncoplastic surgery, conservative mastectomy, and sentinel node biopsy and axillary dissection. The final part of the book covers different forms of surgery and other treatments in particular settings. Topics include plastic and reconstructive surgery, DCIS surgery, radio-guided surgery, adjuvant systemic therapy, intraoperative radiotherapy, and the role of surgery in locally advanced and metastatic disease. The detailed descriptions of techniques are accompanied by numerous high-quality illustrations. This book will be of value to both experienced practitioners and surgical trainees.    ​

This book covers the fundamentals of tissue engineering for the heart, starting with the basics of organ generation, sensors in tissue and organ fabrication, and the current state-of-the-art in stem cell engineering for the heart. With this foundation in place, the remaining chapters focus on specific aspects of the cardiovascular system, starting with heart muscle, then biological pumps, followed by bioartificial ventricles, and finally, bioartificial hearts. Throughout the course of this book, twenty-two in-depth case studies are presented. Each case study has been selected to illustrate specific design schemes for tissue and organ fabrication. This is an ideal book for upper-level undergraduate and graduate students studying tissue engineering and organ regeneration, especially those focused on cardiac regeneration. This book also: Includes twenty-two case studies that illustrate specific design schemes for engineering the heart Provides open-ended discussion questions at the end of each chapter as well as a detailed reference list to encourage further research and reading Covers the basics of organ fabrication as well as sensor technology and genetic engineering as they relate to tissue and organ fabrication

Pericardial disease is a broad term that describes a wide range of pathologies. The clinical aspects of pericardial disease encompass acute pericarditis, pericardial tamponade, pericardial effusion, constrictive pericarditis, and effusive-constrictive pericarditis. Those disorders differ not only in clinical presentation but also in the timeline of disease development; for example, pericardial tamponade is commonly an acute, life-threatening event, whereas constrictive pericarditis is a chronic process developing over months to years. Therefore, pericardial disease management is challenging for most clinicians. The evidence base in the field is relatively scarce compared with other disease entities in cardiology. European Society of Cardiology released guidelines for the diagnosis and management of pericardial diseases. Currently there are no guidelines from American cardiology societies to help clinicians in dealing with pericardial disease. In this book, my goal is to provide extensive review of pericardial disease evaluation and management. A unified, stepwise pathway-based approach for the management of pericardial disease is provided at the end of the book.

This book focuses on how ventricular assist devices (VADs) can help provide destination therapy for patients with terminal heart failure, one of the most serious diseases in the world today because of the tremendous number of patients, the high mortality rate, and the cost of care. One means of providing cardiological support for patients suffering from heart failure is with VADs, and more than 10,000 patients worldwide have now been implanted with these devices. Half of them already have lived more than one year, and 2,000 patients more than two years, after surgery. This improved survival means that we have reached a point where VADs can be used for destination therapy, not just for bridge-to-recovery or bridge-to-transplant. In view of the increasing number of patients with advanced-stage heart failure and the availability and longevity of transplanted hearts, VADs can solve many problems. In addition to providing information about the devices themselves, this book includes vital guidelines on long-term management and support of VAD-implanted patients' everyday lives.

The treatment of end-stage heart failure with advanced surgical therapies has evolved significantly over the last several years and is a dynamic subspecialty within cardiac surgery. Surgical Treatment for Advanced Heart Failure describes the surgical management of advanced heart failure, including coronary artery revascularization, mitral valve repair, aortic valve replacement, ventricular remodeling, cardiac resynchronization, mechanical circulatory support with short-term devices for acute stabilization, long-term mechanical support as a bridge to transplant and for destination therapy, left ventricular assist devices, complete cardiac replacement with the total artificial heart, and cardiac transplantation. With contributions from a distinguished group of heart failure cardiologists and transplant surgeons, it is an authoritative resource for cardiac surgeons, cardiologists, and surgeons.

Surgical Management of Benign Esophageal Disorders: The "Chicago Approach" covers all stages of the diagnosis and treatment of the most common benign esophageal disorders in a concise and easy-to-read format.Indications, patient preparation, operative techniques, and strategies for avoiding and managing complications are included and based both on evidence-based data and the experience of the most famous esophageal surgeons in the United States and abroad. Each chapter includes a summary of the current management strategy for the disease process, and a review of current state of the art techniques provided by world leaders on esophageal disease, surgeons and gastroenterologists alike. A special emphasis is given to emerging procedures in laparoscopy, thoracoscopy, and endoscopy. Surgical Management of Benign Esophageal Disorders: The "Chicago Approach" is illustrated throughout with line diagrams that depict fundamental anatomic or technical principles and is a valuable resource for surgeons and gastroenterologists in residence and training.

This book provides an up-to-date review of current management techniques for Non-Small Cell Lung Cancer. It addresses all of the latest issues that have been raised by the discovery of oncogenic drivers and the improvement of diagnosis and therapeutic methods, including new radiotherapy techniques and anticancer strategies like immunotherapy. New strategies for patients with molecular alterations and the management of particular types of cases are also highlighted. Written by recognized experts in their field, the book represents a unique and valuable resource in the field of lung cancer, both for those currently in training and for those already in clinical or research practice.

This book describes the current applications of the robotic system in general surgery, focusing on the technical aspects of the procedures most commonly performed by this means. It provides a comprehensive overview of the state of the art in robotic surgery and presents the most recently available evidence as documented in the literature. The opening chapters review robotic platforms, discuss the general advantages, limitations, and strategies of robotic surgery, and identify challenges and critical elements when setting up a robotic program. The full range of applications of the robotic system is then covered, encompassing thoracic, esophageal, gastric, hepatobiliopancreatic, splenic, colorectal, endocrine, and transplantation surgery. Detailed attention is also paid to innovative applications and future trends in the robotic platform, with inclusion of a special chapter on fluorescence imaging during robotic procedures. The book closes by considering aspects related to credentialing and privileging, such as mentoring, proctoring, and teaching modules for residents and fellows. Against the background of increasing acceptance of the robotic surgery system across the globe, this book will be invaluable for all general surgeons. There is no doubt that within general surgery the system will continue to flourish on account of its undoubted technical advantages, which minimize most of the intrinsic shortcomings of laparoscopy.