The first in the Problems in Anesthesia seris, Cardiothoracic Surgery examine and provide guidance for a number of problematic clinical scenarios in cardiothoracic surgery anesthesia. This is a field which is growing in complexity due to the increasingly diverse set of conditions that are now treated surgically, and also due to developments in technology which are leading to different approaches to even common problems. This book will be of interest to the qualified specialist and the general trainee in anesthesiology.

Cases are presented followed by an approach to the case, utilizing the various experiences of anesthesiologists from both sides of the Atlantic. The case-based teaching relates the material to the clinic, and the discussion then explains the options in approach. Each chapter concludes with a series of essential tips in dealing with the various problems. Cases covered range from the common (e.g. off-pump coronary bypass) to the rare (e.g. anesthetic management of the patient with carcinoid heart disease).

The aim of the book is to allow readers to learn from both the successes and the complications within the cases covered, and in this way disseminate knowledge amongst those working in the field as well as pave the way for further investigation and continued advancement.

The revised fourth edition of this classic textbook on cardiac anatomy written from the stance of the cardiac surgeon features many new images, including computed tomography angiography. The provision of multiple high quality surgical and pathological photographs makes it essential reading for cardiac surgeons, and of great value to cardiologists, surgical pathologists, radiologists and anaesthetists. The book will also be a valuable reference resource for any healthcare professional or researcher who needs to understand detailed cardiac anatomy. The book begins by describing the surgical approaches to the heart. It goes on to discuss the normal surgical anatomy of the cardiac chambers, the valves, and the systems for circulation and conduction within the heart. This provides the essential anatomical information required to assess and interpret the malformations, lesions and abnormalities discussed in the remainder of the book.

The recent widespread application of minimally invasive techniques has had a profound impact on the diagnosis and therapy of thoracic disorders, including in the pediatric age group. This book is intended as a practical guide to the current approaches in pediatric thoracic surgery. Up-to-date information is provided on the surgical techniques employed for diagnosis and therapy in a wide range of congenital and acquired thoracic pathologies from the prenatal age to adolescence. Among the disorders considered in detail are cystic malformations of the lung, chest wall deformities, diaphragmatic hernias, esophageal anomalies, mediastinal tumors, laryngeal anomalies, and thoracic infections. The authors are distinguished experts in the field from across the world. "Pediatric Thoracic Surgery" will be of value not only for pediatric thoracic surgeons but also for adult thoracic surgeons, pediatric anesthetists, and pediatric respiratory physicians.

Principles of Heart Valve Engineering is the first comprehensive resource for heart valve engineering that covers a wide range of topics, including biology, epidemiology, imaging and cardiovascular medicine. It focuses on valves, therapies, and how to develop safer and more durable artificial valves. The book is suitable for an interdisciplinary audience, with contributions from bioengineers and cardiologists that includes coverage of valvular and potential future developments. This book provides an opportunity for bioengineers to study all topics relating to heart valve engineering in a single book as written by subject matter experts.

Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. The book provides access to knowledge of molecular and cellular aspects of lung homeostasis and repair, including the molecular basis of lung epithelial intercellular communication and lung epithelial channels and transporters. Also included is coverage of lung epithelial biology as it relates to fluid balance, basic ion/fluid molecular processes, and human disease. Useful to physician and clinical scientists, the contents of this book compile the important and most current findings about the role of epithelial cells in lung disease. Medical and graduate students, postdoctoral and clinical fellows, as well as clinicians interested in the mechanistic basis for lung disease will benefit from the books examination of principles of lung epithelium functions in physiological condition.

This is the first of a three-volume project aimed at providing unique case reports (20 cases per volume) of a large number of supraventricular and ventricular arrhythmias encountered in clinical practice. The book is focused on the treatment of supraventricular arrhythmias, namely focal atrial tachycardias, typical and atypical AVNRT and accessory pathways (both manifest and concealed). All presented-cases were performed using the CARTO electro-anatomical mapping system, which allows the reader to better understand the arrhythmia features due to the high number of images provided. A large number of high-quality figures, which represent the core of the authors' work, enrich the contents: all cases are built around suggestive figures acquired during the patients' hospitalization, which clearly illustrate important concepts used in catheter ablation of cardiac arrhythmias. The figures are not only related to the catheter ablation procedure, but also to the patient history, thus helping the reader to place the invasive treatment of the arrhythmias into clinical context: electrocardiograms, Holter ECGs, signal-averaged ECGs, chest X-Rays, transthoracic and transesophageal echocardiography images, MRI, CT scans, coronary angiography images are provided when considered relevant, in order to better present the patient's condition. Short videoclips with activation maps of the atria or the ventricles during the studied arrhythmia complete the information provided. Teaching-oriented, all chapters include questions and answers and key messages at the end of each case. For this reason, it will be an invaluable tool for cardiologists, clinical cardiac electrophysiologists, and interventional cardiac electrophysiologists in training, but also for all those interested in learning more about the subject.

Written by skilled specialists in the field of interventional pulmonology, the new Second Edition thoroughly explores the latest advancements, newest therapies, and diagnostic techniques in interventional pulmonary medicine. Using guidelines to ensure maximum quality and efficiency in patient care, this concise text is a must-have resource for all pulmonologists and critical care specialists. Key features: Covers the latest applications of bronchoscopic therapy for benign conditions (such as COPD and asthma), including endobronchial valves, airway bypass, chemical applications, and thermoplasty Includes diagnostic techniques for airway cancer and peripheral lesions: fluorescence, narrow band, and navigational bronchoscopy, OCT, confocal and raman microscopy, and peripheral EBUS Features new bronchoscopic instrumentation, including the Ultra Thin Scope and Therapeutic Scope, and biopsy measuring and foreign body devices

In this issue of Thoracic Surgery Clinics, guest editor Dr. Gita Mody brings her considerable expertise to the topic of Global Thoracic Surgery. An all-new topic to Thoracic Surgery Clinics, global thoracic surgery is an essential component of public and global health. In this issue, top experts provide timely insights on training, anesthesia, pathology, radiology, techniques, and surgical management of common thoracic surgeries throughout low-middle income countries (LMICs). Contains 14 relevant, practice-oriented topics including esophageal cancer treatment globally; lung cancer management in LMICs; endoscopy and bronchoscopy in low-resource settings; surgical capacity building for low-resource settings; training general thoracic surgeons in LMICs; and more. Provides in-depth clinical reviews on global thoracic surgery, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In Thoracic Surgery: 50 Challenging Cases, editor Wickii T. Vigneswaran has selected 50 challenging cases presented by leading thoracic surgeons. Each case highlights a unique situation from which other surgeons can learn. The selection of Cases includes patients with diagnostic challenges, unconventional and innovative solutions, unexpected findings, and new techniques to treat old problems. The discussions after each case provide a useful starting point for further inquiry. Amply illustrated, this book reflects the wisdom and experience of world leaders in thoracic surgery and teaches junior surgeons how to approach the key thoracic surgical procedures, and how to manage in unexpected and difficult situations. This is a Masterclass in thoracic surgery. Editor Bio Wickii T. Vigneswaran is the Professor and Chief of Thoracic Surgery for the Department of Thoracic and Cardiovascular Surgery at Loyola University Health System.

This new edition of the bestselling step-by-step introduction to cardiac pacemakers now includes additional material on CRT and an accompanying website. It retains the effective use of full-page illustrations and short explanations that gained the book such enormous popularity and now provides information on recent advances in cardiac pacing, including biventricular pacing for the treatment of heart failure.

In this issue of Surgical Clinics, guest editor Dr. Daniel G. Cuadrado brings his considerable expertise to the topic of Cardiothoracic Surgery. In this issue, top experts in the field provide updates on the most common procedures in cardiothoracic surgery, including articles on the lung, heart and chest, as well as two articles on epidemiology that give an accurate scope of heart disease. Contains 15 relevant, practice-oriented topics including lung cancer: epidemiology and screening; open surgical and extended resections for lung cancer; surgical management of pneumothorax and pleural space disease; management of coronary artery disease; minimally invasive and sub-lobar resections for lung cancer; and more. Provides in-depth clinical reviews on cardiothoracic surgery, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

The dramatic race to transplant the first human heart spanned two years, three continents and five cities against a backdrop of searing tension, scientific brilliance, ethical controversy, racial strife and emotional turmoil. It culminated in a terrifying moment in the early hours of 3 December 1967 when, in a cramped operating theatre in a Cape Town hospital, Professor Chris Barnard stared into an empty cavity from which he had just removed a heart. He knew that he had only minutes left to make history and save the life of a 55-year-old man by filling the gaping hole in his chest with a heart which had just been beating inside a 25-year-old woman. Every Second Countsis the story of this gripping race to conquer the greatest of medical challenges. It also reveals the truth about the man at the centre of it all, whose turbulent life story was just as gripping. The kind of true story that would be dismissed as far-fetched if presented as fiction, it combines an utterly compelling portrait of cutting-edge science with raw human drama, and shows how the course of medicine itself was changed for ever.

This extensively revised new edition comprehensively reviews the medical and surgical management of the acutely-ill child with congenital and acquired cardiac disease. It enables the reader to gain a thorough understanding of basic and practical concepts of anatomy, pathophysiology, surgical techniques and peri-operative management in this group of patients. Extensively revised chapters cover the management of cardiac patients on extracorporeal membrane oxygenation, hemofiltration, and plasma exchange. New topics covered include the use of pharmaceuticals in cardiac intensive care, the implications of interventional cardiology in pediatric intensive care and ventricular assist devices. Practically relevant guidelines are also included for cardiovascular nurses. Critical Care of Children with Heart Disease presents a thorough review of the practical concepts, available treatment techniques, and the challenges associated with managing these patients in the critical care unit. It represents a timely and valuable textbook reference for students and practising healthcare professionals alike seeking to learn or further their understanding of the latest advances in this discipline.

In this issue of Thoracic Surgery Clinics, Guest Editor Farid Shamji brings considerable expertise to the topic of Lung Cancer in this second issue covering this topic. Top experts in the field cover key topics such as biological treatments, improving anesthesia safety in pulmonary resection for lung cancer, history of surgical instruments in thoracic surgery, The Hemithorax - the empty chest syndrome, and more. Provides in-depth, clinical reviews on lung cancer, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. Contains 16 relevant, practice-oriented topics including Assessment of Operability and Resectability in Lung Cancer; Complications of chest wall resection in conjunction with pulmonary resection; Sepsis in the postpneumonectomy space: pathogenesis, recognition and management; Neuroendocrine cancers of the lung: natural history, pathological classification, biological behaviour and treatment; and more.

In this issue of Thoracic Surgery Clinics, Guest Editor Cherie Erkmen brings considerable expertise to the topic of social disparities in thoracic surgery. Top experts in the field cover key topics such as social disparities in lung cancer, population health, esophageal cancer, benign lung diseases, and more. Provides in-depth, clinical reviews on social disparities in thoracic surgery, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. Contains 12 relevant, practice-oriented topics including Social Disparities Database and Big Data; Health Disparities in Recruitment and Enrollment in Research; Social Disparities in Lung Cancer Risk and Screening; and more.

The number of ICD patients is increasing sharply, yet the number of electrophysiologists--physicians who specialize in the electrical system of the heart--is not increasing as dramatically. The result of this influx is that more and more ICD patients are being treated by physicians and staff with little or no ICD training.

There are many fine books on device-based therapy for the heart, but most are written for the experts. Whether you read it from cover-to-cover or use it for reference (or both), it is written primarily with you in mind - for people who are actually involved in the clinical care of these patients.

"The Nuts and Bolts of ICD Therapy" is specifically written for non-cardiologists. This book is written in a lively intelligent and easy to navigate style. It emphasizes real-life clinical practice and practical tips, including illustrations from actual clinical settings. Each chapter concludes with a checklist of key points from each subject ("Nuts and Bolts").

Despite often taken as a simple procedure, techniques on tracheostomy have evolved considerably on the last few years. Consequently, new technical variations and indications for different purposes are being developed and proposed. The current book is proposed to serve as a comprehensive guide exclusively devoted to tracheostomy, discussing its most important details, variations and indications. Here the reader will find a broad discussion ranging from the most basic pre-clinical aspects to post-surgical procedures and complications. Great emphasis is placed on key topics such as the oncologic patient, variations of the technique, and tracheostomy in the intensive care unit, among others. Additionally, some issues that are not commonly discussed in regular textbooks, like tracheostomy in child and in great obese, are also included. With a wealth of photos, illustrations and tables, Tracheostomy - A Surgical Guide provides the material necessary to support a safe and effective surgical intervention in different populations and surgical contexts, with the hope that it will result in improved care for patients who underwent tracheostomy.

In this issue of Thoracic Surgery Clinics, guest editor Farid Shamji brings considerable expertise to the topic of Lung Cancer. Provides in-depth, clinical reviews on Lung Cancer, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

This issue of Thoracic Surgery Clinics, guest edited by Drs. Stephen Hazelrigg and Traves Crabtree, is devoted to Surgical Management of Benign Lung Disease. Drs. Hazelrigg and Crabtree have assembled expert authors to review the following topics: Evaluation of the emphysema patient: Best medical treatment and indications for surgical intervention; Life expectancy after lung volume reduction surgery; Analysis of recent literature on lung volume reduction surgery; Present role of endobronchial valves in emphysema treatment; Critical Analysis of the National Emphysema Treatment Trial Results for Lung-Volume-Reduction Surgery; Technical aspects of LVRS including anesthetic management and surgical approaches; Future treatment of emphysema with roles for valves and LVRS; Alpha one antitrypsin disease, treatment and role for lung volume reduction surgery; Postoperative Air-Leaks after Lung Surgery: Predictors, Intraoperative Techniques, and Postoperative Management; Value of a multidisciplinary team approach to treatment of emphysema; Economic considerations with endobronchial valves and lung volume reduction surgery; Outcomes of lung volume reduction surgery in homogenous emphysema; and more!

The sober explanation for this book is a call by the Springer-Verlag, London, to edit a publication on ‘The functional relevance of the collateral circulation’ of the heart. Alternatively, it could be ‘sold’ as the result of my intention to reduce entropy of 18 years of scientific work on the topic of the coronary circulation, which was itself meant to diminish the amount of ‘useless’ energy. Such a process of reducing disarray in a system with the aim of grasping it better is related to simplification, which carries the risk of introducing error. This can be exemplified by the historic view of angina pectoris, which used to be simplified as being always fatal, thus obscuring for nearly two centuries the view of a ‘self-healing’ mechanism such as the collateral circulation of the heart. It would be na?¨ve, to assume the present work to be free of erroneous oversimplification, because the very nature of scientific work is related to generating (simple) hypotheses with their subsequent falsification. In that context and bluntly, my primary interest in the field of the collateral circulation was not initiated with a vision of eradicating the consequences of coronary artery disease (CAD) by promoting the growth of natural bypasses. The time for such sizeable ideas had passed in the 1970s with the start of the work by Wolfgang Schaper.

This issue of Thoracic Surgery Clinics, guest edited by Drs. Dean Donahue and Hugh G. Auchincloss, is devoted to Thoracic Outlet Syndrome. Drs. Donahue and Auchincloss have assembled expert authors to review the following topics: Embryology and Anatomy of the Thoracic Outlet; Evaluation of Patients with Neurogenic Thoracic Outlet Syndrome; Reoperation for Persistent or Recurrent Neurogenic Thoracic Outlet Syndrome; Surgical Technique: Supraclavicular First Rib Resection; Evaluation and Management of Venous Thoracic Outlet Syndrome; How Common is Thoracic Outlet Syndrome?; Surgical Technique: Minimally Invasive First Rib Resection; Radiographic Evaluation of Thoracic Outlet Syndrome; Evaluation and Management of Arterial Thoracic Outlet Syndrome; and more!

This book addresses the most technically demanding but life-changing techniques in the treatment of conotruncal heart defects, as many repairs are performed on small infants. Each chapter reviews surgical anatomy (the anatomical classification that the surgeon is using), preoperative evaluation (the surgeon's check list before doing the surgery), and surgical techniques (clear drawings and videos, minimal text). It is an essential reference book for newly qualified surgeons when performing these complex cases. Conotruncal heart defects (CTHDs) are a group of complex congenital anomalies of the cardiovascular system that are a major cause of symptomatic cardiac disease at birth. They may account for up to 30% of all congenital cardiac anomalies. In many instances, patients with CTHD are symptomatic in the first days or weeks of life, with severe cyanosis or heart failure, requiring surgery in the neonatal period or in infancy. Most CHTD are today diagnosed in utero by fetal ultrasound. CHTDs are usually defined as malformations of the cardiac outflow tracts and presumably result in disturbance in the development of the cono-truncal apparatus of the embryonic heart, as well as of the primitive aortic arches. CTHDs include the following: truncus arteriosus, tetralogy of Fallot, double outlet right (or left) ventricle, transposition of the arteries, corrected transposition of the great arteries, interrupted aortic arch. The outcomes of CHTD surgery has considerably improved in the past 20 years, with quite fascinating innovations.

In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize

This issue of Thoracic Surgery Clinics, guest edited by Drs. Jyoti Patel and Jessica Donington, is devoted to Advances in Systemic Therapy for Non-Small Cell Lung Cancer. Drs. Patel and Donington have assembled expert authors to review the following topics: Adjuvant and Neoadjuvant Immunotherapy; Combining Immunotherapy with Radiation in Lung Cancer; Adjuvant Chemotherapy; ALK Mutations; Molecular Targets Beyond the Big 3; Advances in Systemic Therapy; Liquid Biopsies in NSCLC; Combining Immunotherapy and Chemotherapy for NSCLC; ROS-1 Mutations; EGFR Mutations; and more!

This book covers in detail all aspects of functional mitral and tricuspid regurgitation, from its pathophysiology and natural history, to its assessment, medical and surgical treatment, and long term results. Functional Mitral and Tricuspid Regurgitation encompasses information and knowledge from a diverse background including cardiology, cardiac surgery and basic science. This is necessary for a full understanding of the subject in order to optimally manage patients with this condition.