This book is a practical guide to the differential diagnosis and treatment of patients presenting in the Emergency Department with syncope or arrhythmias, including bradyarrhythmias, atrial fibrillation, narrow and wide QRS tachycardias. In addition, clear advice is provided on the management of patients with cardiac devices and possible dysfunction, electrical storm, or a requirement for urgent surgery. For each topic, a literature review of epidemiology, physiopathology, differential diagnosis, and treatment is conducted. Furthermore, practical suggestions are offered for short-term management, e.g., regarding the decision on when and where to hospitalize the patient; these proposals do not replace but rather summarize or integrate the current guidelines. The book is designed both for emergency physicians and cardiologists, who will be the first to evaluate and treat patients with arrhythmias or potentially arrhythmic problems in the emergency setting. It will also be a useful textbook for students and residents in Cardiology and Emergency Medicine.

This new edition provides the latest information and insights into the molecular basis for lung cancer. Since the publication of the previous edition of this volume, dramatic changes have occurred with the classification of lung cancer, biomarker testing, and molecular therapy. The book covers these changes, providing updates and new insights on the background of lung cancer, testing methods, and the molecular pathology of specific cell types, including adenocarcinoma, squamous cell carcinoma, small cell carcinoma, and precursor and preinvasive lesions. Authored by experts in the field, Precision Molecular Pathology of Lung Cancer, Second Edition remains one of the few books that comprehensively covers the new molecular pathology of lung cancer and is a valuable resource for pathologists, medical oncologists, radiation oncologists, thoracic surgeons, and thoracic radiologists.

This book provides a comprehensive, practical and timely review of all aspects of video-assisted, minimally invasive thoracic surgery, used to treat conditions of the lung, pleura, mediastinum, chest wall and diaphragm. Advances in technologies and instrumentation mean almost all thoracic surgeries may be performed by minimally invasive techniques rather than the traditional open surgeries. This book describes the thoracoscopic procedures in current specialist practice with discussion on indications, patient selection, surgical approaches, complications and clinical outcomes. The book opens with a summary of the rationale for minimally invasive surgery and when to convert to open surgery, as well as anaesthetic and peri-operative considerations, before covering the range of procedures organised by anatomical site. Numerous figures and diagrams describe every technique in detail and an authoritative, international team of contributors provides clinical experience and expert guidance.

This book presents and describes a series of informative clinical cases with the aim of providing the reader with a clear understanding of the most frequent and challenging scenarios that a cardiologist may face during daily clinical practice. All major topics in modern clinical cardiology are addressed, including acute ischemic heart disease, conditions that mimic ischemic heart disease, heart failure and resynchronization therapy, cardiomyopathy, valvular heart disease, arrhythmias and channelopathies. Guidance is provided on imaging techniques and their interpretation, patient management taking into account potential comorbidities and follow-up appropriate to the clinical circumstances. The paradigmatic clinical cases in this book will serve as a sound basis for learning for medical students, residents and others wishing to meet successfully the challenges posed by cardiac disease. In addition, the book will be a very useful reference for the more experienced cardiologist.

This book provides new perspectives on the pathogenesis of atherosclerosis. Chapters cover atherosclerosis risk factors, the effect of growth and aging on vascular architecture, and the crucial role the microvasculature plays in atherosclerosis development. Microvascular dysfunction would explain why the well-known risk factors actually put individuals at higher risk. This pathomechanism would also hold true not only for obstructive atheroma formation but also for aneurysmal dilatation as well as for aortic and peripheral artery dissection. When seen through this lens, novel preventive and therapeutic opportunities can be envisioned. Atherosclerosis Pathogenesis and Microvascular Dysfunction proposes a single unifying mechanism of atherosclerosis development and describes potential preventative and therapeutic avenues based on this concept. It therefore represents a timely and valuable resource for internal medicine, cardiology, angiology cardiovascular surgeons, pathology clinicians, researchers, trainees, and students.

This textbook offers an up-to-date, user-friendly guide on the evaluation, diagnosis and treatment of heart failure. Each chapter is dedicated to providing comprehensive coverage of every aspect of heart failure from cardiac signs and symptoms through imaging and the genetic basis for disease to surgery, interventions, treatment and preventative cardiology. Heart Failure provides the trainee and practising cardiologist, cardiac surgeon, vascular surgeon, diabetologist, cardiac radiologist and any physician who manages cardiac patients with a valuable resource featuring extensive guidance on the diagnosis and management of a range of conditions related to heart failure.

Although the incidence of coronary heart disease is falling, its major complication, heart failure, is increasing in frequency. All health care practitioners will encounter patients with heart failure, presenting either acutely or in need of chronic heart failure management. However with recent advances in medical therapy, the prognosis of the condition has improved dramatically so that whereas once heart failure was a pre-terminal diagnosis, now for many it is treatable. Taking the reader from an understanding of the basic mechanisms of heart failure through to an appreciation of the complexities of heart failure management and the remarkable improvements possible with good treatment, this definitive textbook is written by internationally renowned leaders in their field and comprehensively covers all aspects necessary to manage a patient with heart failure. In full colour throughout, containing over 300 illustrations, and supported by detailed referencing from the huge evidence base that has developed over the last two decades, Oxford Textbook of Heart Failure also includes extensive chapters on common co-morbidities, and will be essential reading for consultant cardiologists and those in training, general physicians and those caring of the elderly, cardiothoracic surgeons, primary care doctors, pharmacists, and specialist nurses. The printed edition is complemented by 6 months free access to an online version (also available for separate purchase on subscription basis), allowing users to search the text, and download the figures for use in PowerPoint presentations.

This book with accompanying videos focuses on pectus excavatum correction using custom-made silicone implants. It discusses patient evaluation, the minimally invasive procedure and follow-up care. It also describes in detail, and in a way that is comprehensible for practicing clinicians, the procedure for creating silicone implants using a scanner (computer-aided design). Further, the book presents the possibility of using fat grafting to correct this congenital deformity and highlights secondary surgical procedures and complications (e.g. infections). Correcting pectus excavatum using a computer-aided design silicone implant is a simple and reliable technique that yields high-quality, aesthetic results. In the medium term, the approach may render invasive techniques obsolete, however, these operations remain risky.

This book provides medical care givers with detailed information on those aspects of adolescence that are of significance in the setting of congenital heart disease (CHD), from anatomic and physiologic changes to behavioral issues. In addition, it explains how care should be organized in order to ensure that the needs of adolescents with CHD are fully met. Both theoretical and practical aspects of the switch from a pediatric to an adult health perspective in CHD patients are outlined in detail, drawing attention to the importance of a structured transition plan and other best practices. As the survival of children with complex CHD improves further, the number of adolescents with CHD will continue to grow. Awareness of the challenges that these patients face is essential if they are to be appropriately prepared to assume adult roles and functioning. Readers will find Congenital Heart Disease and Adolescence to be an excellent source of relevant knowledge and guidance. It has been written for a broad audience, bearing in mind that care in adolescents is an interdisciplinary task involving close collaboration among physicians, specialists, nurses, patients, and relatives.

This book explores the unique aspects involved in the management of ECMO patients such as physiopathology and indications, setting up the device, monitoring ECMO and the patient, troubleshooting, ethical aspects and rehabilitation. For the past eight years, management of acute heart failure and Acute Respiratory Distress Syndrome (ARDS) patients has been improved by the development of short-term assistance devices, with ECMO as a first line treatment. This highly informative book provides essential insights for ICU nurses at ECMO centers around the world, who face the substantial challenges involved in the management of ECMO patients. Above all, it meets their training needs with regard to bedside monitoring for these patients, which has become a major issue. The editors and most of the contributors serve at La Pitie-Salpetriere ICU, France, which, in terms of the number of admissions and major publications produced, is one of the world's leading authorities on ECMO.

In recent years the approach towards rib fractures has evolved. Abandoned in the past, due to inadequate instrumentation and lack of evidence, rib fixation has recently re-emerged as a treatment option for trauma patients. There have been a number of advances over the last 25 years that now allow surgeons to internally fix rib fractures that otherwise may have not had other options. However, as a result there has been a rapid increase in literature and many institutions interested in initiating rib fixation programs. Due to a variety of practitioners involved namely, trauma surgeons, orthopedic surgeons, and thoracic surgeons there has been no comprehensive guide to patient selection, technique, and post-operative care. The purpose of this text is to fill the educational gap for those trauma, orthopedic, and thoracic surgeons interested in learning the cutting edge evidence-based approaches to treatment of rib fractures. This topic has caught the interest of many and has been a recurrent theme at surgical meetings over the last two years. Although there has been ever increasing levels of interest and experience nationally there are many questions which remain. This text will provide not only the theoretical background for improving outcomes in those with rib fractures but also serve as a practical guide to those interested in starting new programs. The text will include tips and tricks that can be used in the OR or at the bedside to improve patient care. Therefore, the focus will be on a comprehensive review but also including tips and tricks from the most experienced surgeons around the country who are performing internal fixation for rib fractures.

Significant changes have taken place in the realm of cardiac, thoracic, and vascular surgery during the last five to ten years. Many new operative procedures have been developed which remain relatively unknown to cardiothoracic surgeons. This practical manual covers a wide variety of these new processes, several of which are interventions offered to cardiologists practicing in the field of electrophysiology who are unaware that these interventions exist and can help them in situations they cannot solve. It includes general practical techniques; cardiac, thoracic, and vascular surgery procedures; and advances in cardiology and electrophysiology. Throughout the book, illustrations accompany the technical descriptions and show in step-by-step detail how to perform the operations and various procedures using proper equipment. Cardiothoracic Surgical Procedures and Techniques: A Practical Manual is an essential resource for physicians and related professionals, residents, fellows, physician assistants (PA), and graduate students in cardiology, cardiac surgery, thoracic surgery, and vascular surgery.

Advances in technology and human skill have made possible percutaneous catheter-based procedures for a wide spectrum of structural heart disease. A growing number of structural heart diseases that over the past two decades would have required open heart surgery can be safely treated using percutaneous catheter-based procedures.Traditionally, guidance of catheter-based procedures is done using fluoroscopy and two-dimensional transesophageal echocardiography (2D TEE). The recent introduction in the clinical practice of RT 3D TEE has overcome most of limitations of 2D TEE. The purpose of this book is to describe the use of this imaging modality in percutaneous interventional procedures underlying its growing role and acceptance among the interventional cardiologists but also emphasizing areas of weakness. Because today interventional cardiology ranges from closure of atrial and ventricular septal defects, to repair of mitral regurgitation and aortic stenosis, from the closure of left atrial appendage and prosthesis dehiscence, to the recent use in electrophysiological procedure, this book targets not only specialists in echocardiography and interventional cardiology but also general cardiologists. General cardiologists will find in any chapter anatomy of the structure treated (i.e. atrial septum, mitral valve...), a description of the morphopathology as seen with RT 3D TEE (degenerative or ischemic mitral regurgitation) the up-to-date indications to the specific percutaneous treatment and typical and unusual clinical cases.

This book is designed to present readers with comprehensive, high-quality research results on almost all aspects of this carcinoma in clinical management, from correct determination of the esophagogastric junction, issues on cardiac mucosa, epidemiology, and natural history, to clinical, endoscopic, and histopathologic features and diagnostic pitfalls of this carcinoma at both early and advanced stages. Once diagnosed and correctly staged, clinical management of this carcinoma at the early stage is addressed primarily with endoscopic therapy employing the latest endoscopic technology such as endoscopic submucosal dissection, in which detailed technical topics of the endoscopic therapy are written by experts in the field with sections from pre-resection staging and patient preparation to post-resection complications and management. Subsequently, clinical management of gastric cardiac carcinoma at advanced stages is discussed at length with a personalized, multidiscipline approach with strategies from surgical resections with various methods, to pre-, peri- and post-resection chemoradiation therapies as well as the most advanced immunotherapy. A state-of-art approach with the results of meta-analyses and large-scale randomized double-blinded clinical trials are employed throughout these chapters. For patients at the terminal ill stage, the appropriate palliative care plan is presented by experienced clinicians armed with the latest clinical practice guidelines to better manage and help those patients in the last period of their lives.

This book provides a comprehensive surgical atlas of functional single ventricle and hypoplastic left heart syndrome, based on theoretical insights and a wealth of clinical practice. It offers anatomical morphology and descriptive texts, while also highlighting key aspects of each procedure. The book is divided into three major parts, the first two of which illustrate the procedures for the palliation of functional single ventricle and hypoplastic left heart syndrome respectively, including the fundamental concepts, derivatives, evolutionary process, and criterion for the staged Fontan procedure. In turn, part three highlights advances in computational simulation for cardiological applications. Featuring well-illustrated, clearly structured instructions, the book offers a valuable guide to functional single ventricle and hypoplastic left heart syndrome for cardiologists around the globe.

This book describes the multimodality imaging of cardiac, lung, liver, kidney, pancreas, and small bowel transplants in donors and recipients. The volume of transplantation of solid organs has increased substantially and has become common practice in medicine. Radiological evaluation of transplanted organs such as the heart, lungs, liver, pancreas, and kidneys is critical, both in potential donors (as is the case in liver and kidney transplantation) and in preoperative and postoperative evaluations of recipients. Understanding the often complex surgical anastomoses and unique pathology is necessary to inform radiologic interpretation. This book provides radiologists with the knowledge of the normal appearance of a transplanted organ, an understanding of imaging modalities that are best suited to answering clinical questions, an overview of the pathologies related to such organs and their appearance on various modalities, vascular and nonvascular complications, and techniques related to image-guided transplant interventions.

Highly Commended, BMA Medical Book Awards 2015 Since the first edition of this book was published in 2004, the management of congenital heart disease has continued to evolve at a rapid pace. Not only have new operations been developed and expanded, such as the intra/extracardiac conduit Fontan and the double root translocation for corrected transposition, but in addition, diagnostic methods-particularly cardiac CT and MRI-have been dramatically transformed. Understanding of the genetic basis of congenital heart disease and the embryology of cardiac development has progressed even more rapidly. What has not changed is that optimal outcomes for children and adults with congenital heart disease can only be achieved by a collaborative team effort. The team includes not only congenital cardiac surgeons but also pediatric cardiac nurses, pediatric cardiologists, perfusion and respiratory technicians, pediatric cardiac intensivists, pediatric cardiac anesthesiologists, ultrasonographers, and MRI and catheter laboratory technicians. This second edition of Comprehensive Surgical Management of Congenital Heart Disease describes in detail the contemporary practice of Richard A. Jonas and the cardiac team at Children's National Medical Center in Washington, D.C. The book once again includes numerous beautiful illustrations providing comprehensive and detailed information about intra-operative management of the entire spectrum of congenital heart surgery. In addition, the companion VitalSource ebook contains more than 50 operative videos that have been edited and narrated to highlight the key steps in complex surgical procedures. The book incorporates an evidence-based approach, supported throughout by numerous scientific citations, to explain when and why an operation should be done as well as the risks, benefits, and potential complications.

Now in a revised and expanded 7th Edition, Kaplan's Cardiac Anesthesia helps you optimize perioperative outcomes for patients undergoing both cardiac and noncardiac surgery. Dr. Joel L. Kaplan, along with associate editors, Drs. John G. T. Augoustides, David L. Reich, and Gerard R. Manecke, guide you through today's clinical challenges, including the newest approaches to perioperative assessment and management, state-of-the art diagnostic techniques, and cardiovascular and coronary physiology. Complete coverage of echocardiography and current monitoring techniques. Guidance from today's leaders in cardiac anesthesia, helping you avoid complications and ensure maximum patient safety. More than 800 full-color illustrations. A new section on anesthetic management of the cardiac patient undergoing noncardiac surgery. New availability as an eBook download for use the in OR. Online-only features, including quarterly updates, an ECG atlas...an increased number of videos, including 2-D and 3-D TEE techniques in real time...and an Annual Year End Highlight from the Journal of Cardiovascular Anesthesia that's posted each February. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices.

This heavily revised second edition of this book provides a comprehensive overview of both common and rarely performed thoracic surgical techniques. Techniques covered include thymectomy, left and right lower lobectomy, rib resection for empyema, median sternotomy and lung biopsies. Emphasis is focused on the practical steps necessary to successfully and reliably perform the techniques covered, while acknowledgement is also given to individual variations in how these techniques are performed. Thoracic Surgical Techniques provides a detailed clinical illustrative guide for successfully performing a range of procedures reliably. Its large number of detailed illustrations and concise technical descriptions provides an invaluable resource for all practising and trainee thoracic surgeons.

Fundamentals of Cardiac Pacing was just honored with 4 Stars from Doody's Book Review! An introductory guide to cardiac pacing, Fundamentals of Cardiac Pacing covers the key topics that residents, fellows, nurses, and other clinical personnel must be familiar with in order to care for the growing number of patients with cardiac pacemakers. This concise and clearly written handbook covers all dimensions of cardiac pacing including indications, technology, implantation techniques, programming, diagnostics, and follow-up as well as evidence-based guidelines for pacemaker implantation, avoidance of complications, and patient preparedness. This is a straightforward, complete and essential guide to the long-term care of patients with cardiac pacemakers, and is the perfect resource for any health care professional.

This book describes the most popular topics concerning adult congenital heart disease (ACHD), especially focusing on indications and re-intervention procedures for some major ACHDs. Thanks to advances in medical and surgical therapy for congenital heart disease over the last half century, many patients who underwent surgical correction reached adulthood. However, as can be seen from the explosive increase in the number of ACHD patients, postoperative residua and sequelae have also become apparent. The purpose of this book is to highlight complicated problems in connection with ACHD, including its present status, as well as methods for its management including medical and surgical treatment. The content primarily focuses on two areas - general information for cardiologists, and information on re-intervention for interventionists and cardiac surgeons -, setting it apart from the majority of books on congenital heart disease.

This thesis addresses computation fluid dynamics modelling of aortic dissection (AD), in order to generate in silico diagnostic information and assess 'virtual surgery' outcomes. The thesis introduces several important advances in the modelling of aortic dissection and lays essential groundwork for further development of this technology. The work thesis represents a unique and major step forward in our understanding of AD using a patient-specific, systematic and coherent simulation approach, and is currently the most advanced work available on AD.

This issue of Thoracic Surgery Clinics, guest edited by Drs. Jyoti Patel and Jessica Donington, is devoted to Advances in Systemic Therapy for Non-Small Cell Lung Cancer. Drs. Patel and Donington have assembled expert authors to review the following topics: Adjuvant and Neoadjuvant Immunotherapy; Combining Immunotherapy with Radiation in Lung Cancer; Adjuvant Chemotherapy; ALK Mutations; Molecular Targets Beyond the Big 3; Advances in Systemic Therapy; Liquid Biopsies in NSCLC; Combining Immunotherapy and Chemotherapy for NSCLC; ROS-1 Mutations; EGFR Mutations; and more!

This concise practical guide is designed to facilitate the clinical decision-making process in the management of LAA occlusion procedures by reviewing a number of cases and defining the various diagnostic and management decisions open to clinicians. Clinical Cases in LAA Occlusion is well illustrated but concise, enabling the reader to obtain relevant information regarding both standard and unusual cases in a rapid, easy to digest format. Each case includes a narrative description and patient management tips.

This is the first comprehensive review of the edge-to-edge technique for mitral repair, which was introduced into the surgical armamentarium in 1991 by one of the authors, Ottavio Alfieri. The surgical technique employed in edge-to-edge repair today provides the basis for the only reliable method of percutaneous correction of degenerative mitral regurgitation. The book traces the evolution of the edge-to-edge technique from a surgical to a percutaneous approach, documenting indications, contraindications, technical aspects, controversies and clinical outcomes. Detailed attention is devoted to the MitraClip procedure, which reproduces the Alfieri stitch percutaneously and has to date been used in more than 20,000 patients worldwide. The state of the art in MitraClip therapy is described, with clear explanation of when and how to use the MitraClip system. The reader will learn all aspects of percutaneous edge-to-edge repair, which is recommended for use in carefully selected patients in the new ESC/EACTS guidelines for the management of valvular heart disease and in the ESC guidelines on heart failure. The group at San Raffaele Hospital, Milan, has accumulated by far the largest experience in the world with the technique and over the years has been very active in its promotion and scientific evaluation. This book reflects that depth of knowledge and will be of great interest to cardiac surgeons and interventional and clinical cardiologists.