Key Features * Provides practical guidance based on real-life Heart Failure scenarios. * Discusses both acute and chronic care patient-oriented scenarios. * Cover up-to-date and novel concepts in heart failure. * Features the perspectives of current debates and controversies in heart failure. * Highlights the opportunities for research in this field.

The refined pathophysiologal understanding of the heart failure syndrome together with the surge of new technological advances led to innovative medical and interventional treatment strategies improving the outcome of heart failure patients. However the complex interplay between the clinical presentation and the array of the interventions requires a coordinated multidisciplinary heart team approach involving various specialists in the cardiovascular field including clinicians, interventionalists, surgeons and cardiac intensivists. In this book, opinion leaders will review of state-of-the-art management of heart failure with particular emphasis on burning clinical questions and challenges faced by the heart team. New medical and interventional therapies for chronic and acute heart failure are addressed by bridging bench to bedside translation in science and technology into practical clinical application and guidance.

For hundreds of years cannabis has been used as a therapeutic medicine around the world. Cannabis was an accepted medicine during the second half of the 19th century, but its use declined because single agent pain medications were advocated by physicians who demanded standardization of medicines. It was not until 1964 when the chemical structure of THC (delta 9-tetrahydrocannabinol) was elucidated and its pharmacological effects began to be understood. Numerous therapeutic effects of cannabis have been reviewed, but cannabis-based medicines are still an enigma because of legal issues. Many patients could benefit from cannabinoids, terpenoids and flavonoids found in Cannabis sativa L. These patients suffer from medical conditions including chronic pain, chronic inflammatory diseases, neurological disorders, and other debilitating illnesses. As more states are legalizing medical cannabis, prescribers need a reliable source which provides clinical information in a succinct format. This book focuses on the science of cannabis as an antioxidant and anti-inflammatory supplement. It discusses cannabis uses in the human body for bone health/osteoporosis; brain injury and trauma; cancer; diabetes; gastrointestinal conditions; mental health disorders; insomnia; pain; anxiety disorders; depression; migraines; eye disorders; and arthritis and inflammation. There is emphasis on using the whole plant - from root to raw leaves and flowers discussing strains, extraction and analysis, and use of cannabis-infused edibles. Features: Provides an understanding of the botanical and biochemistry behind cannabis as well as its use as a dietary supplement. Discusses endocannabinoid system and cannabinoid receptors. Includes information on antioxidant benefits, pain receptors using cannabinoids, and dosage guidelines. Presents research on cannabis treatment plans, drug-cannabis interactions and dosing issues, cannabis vapes, edibles, creams, and suppositories. Multiple appendices including a glossary of cannabis vocabulary, how to use cannabis products, a patient guide and recipes as well as information on cannabis for pets.

Resuscitation is a two-stage process comprising the achievement/maintenance of spontaneous circulation and post- resuscitation management. The approach is complex and multifaceted and entails the integration of new physiological insights, pharmacological options, and technological advances. The purpose of this volume, written by top experts in the field, is to promote, share, and disseminate new advances in resuscitation and post- resuscitation care. The issues addressed are wide ranging and of great topical interest or controversy. They include priorities of intervention, quality of resuscitation, use of mechanical supports, new defibrillation strategies, prevention of organ damage, strategies in cases of sudden cardiac death, new pharmacological treatments, and post-resuscitation care, including temperature management and prediction and improvement of outcome after cardiac arrest. Particular attention is devoted to up-to-date evidence from the most recent experimental and clinical trials on resuscitation science and to gold standard evidence-based resuscitation and post-resuscitation treatments and interventions. In addition, organizational models and integrated care systems for trauma are considered, and critical care education and the process of guideline development are reviewed.

Stem Cells and Myocardial Regeneration is a comprehensive bench to bedside examination of stem cell-based therapies for cardiac dysfunction. The contributors, all leading researchers in their area of expertise, explore recent advances in the laboratory and in clinical trials. This volume emphasizes the near epidemic status of chronic heart failure (CHF) in the United States and abroad, and evaluates the level of success and failure of current optimal medical therapy. Specific attention is also given to both the basic cell types and pathways involved in cardiac stem cell research and the clinical issues that surround it.
Parts I and II of Stem Cells and Myocardial Regeneration examine various cardiac stem cell types, including hematopoietic, mesenchymal, and endogenous cells and critical physiological pathways, including chemokines, stem cell differentiation, and arrhythmia mechanisms. Part III focuses on clinical issues intrinsic to delivery of stem cells to the heart at the time of myocardial infarction (MI) and in patients with CHF. Part IV contains up-to-date reviews and analyses of the findings of stem cell-based clinical trials of acute MI and CHF. The concluding section presents a summary of cardiac stem cell research and outlines potential obstacles to future study.

With cardiovascular disease remaining one of the primary causes of morbidity and mortality worldwide, there is a great need to further understand the molecular basis of this disease class and develop new therapeutic or preventative measures. Cardiovascular Diseases: Nutritional and Therapeutic Interventions presents up-to-date information on the pathobiology of cardiovascular diseases, emphasizing emerging therapeutics and nutritional interventions. The book is divided into four parts: epidemiology, epigenetics, pathobiology, and therapies for cardiovascular diseases. Part I details epidemiological studies, highlighting the extent of the clinical problem. Part II describes the genetic and, primarily, epigenetic modifications associated with cardiovascular disease, including the importance of DNA methylation status and the possibility of early intervention using simple dietary modifications. The text also discusses histone modifications associated with disease and potential therapeutic synthetic and dietary compounds such as resveratrol and garlic. Covering the etiology and pathobiology, part III discusses lipid regulation, micro-RNAs, emerging cell-based therapies, and new receptor targets for therapeutics as well as targeted imaging. It also describes the link between cancer therapies and cardiomyopathy and the potential of vitamin C to ameliorate this effect. Part IV focuses on therapeutic and nutritional interventions, namely, stem cell therapies, emerging nanomedicines, and a wide range of dietary interventions. These include general healthy diets, fruits and vegetables, botanicals, effects of specific compounds such as antioxidants, and discussions on garlic, curcumin, and resveratrol. The text also covers lifestyle factors, emphasizing the importance of stress in the occurrence of and meditation and yoga in the management of cardiovascular disease. This book provides a comprehensive reference for clinicians and scientists, combining epidemiology, prevention, and modern treatment strategies.

The second edition of the book has been revised and updated by experts in the field to incorporate recent advances and will likely remain the largest and most comprehensive text on echocardiography to date with 2,230 pages, 4,361 illustrations and 1,860 video clips. This book is probably the largest book on echocardiography till date. Covers all aspects of echocardiography and cardiovascular ultrasound in a comprehensive manner. Written by over 150 internationally renowned experts in the field of echocardiography from all over the world. Supplemented by a huge number of illustrations and video clips. Written in clear, coherent and easy-to-grasp language.

Taurine 8 represents the combined efforts of investigators on the roles of the amino acid taurine on human health and disease. The chapters covered in this book are directly derived from presentations of the contributors at the 18th International Taurine Meeting held in Marrakech, Morocco in April 2012. The purpose of this book is to disseminate current findings on taurine's contribution in several organ systems. This book covers the following topics: Taurine in Nutrition and Metabolism, the Protective Role of Taurine, and the Role of Taurine in Reproduction, Development, and Differentiation. Dr. Abdeslem El Idrissi, College of Staten Island and Dr. William L'Amoreaux, College of Staten Island, were co-chairs of the Organizing Committee for the meeting. Data presented at this meeting provided compelling evidence that taurine is not only cytoprotective in cardiomyocytes, but also is a potent GABA agonist, whereby it can facilitate vasodilation of conducting arteries. Taurine conjugates, such as taurine chloramine, may protect cells from oxidative stress via increased HO-1 expression. In adult rodents, taurine has a potent effect on plasma glucose levels, likely through the release of insulin in pancreatic beta cells. As a potential neurotransmitter, taurine is known to work via the GABAergic system, but current research presented at this meeting suggest that taurine may interact with glutamate and serotonin receptors as well. Data are also presented to demonstrate the protective roles of taurine on neurons in neuroblastoma. Perhaps the most important and exciting presentation is the role of taurine and alcohol: the combination may be lethal. Data are also presented at this meeting of the potential role taurine may have as an adjuvant treatment with cisplatin in chemotherapy.

Open a Window into the Autonomic Nervous System Quantifying the amount of autonomic nervous system activity in an individual patient can be extremely important, because it provides a gauge of disease severity in a large number of diseases. Heart rate variability (HRV) calculated from both short-term and longer-term electrocardiograms is an ideal window into such autonomic activity for two reasons: one, heart rate is sensitive to autonomic activity in the entire body, and two, recording electrocardiograms is inexpensive and non-invasive unlike other techniques currently available for autonomic assessment, such as microneurography and metaiodobenzylguanidine (MIBG) scanning. Heart Rate Variability (HRV) Signal Analysis: Clinical Applications provides a comprehensive review of three major aspects of HRV: mechanism, technique, and clinical applications. Learn Techniques for HRV Signal Analysis Edited by an engineer, a cardiologist, and a neurologist, and featuring contributions by widely published international researchers, this interdisciplinary book begins by reviewing the many signal processing techniques developed to extract autonomic activity information embedded in heart-rate records. The classical time and frequency domain measures, baroreceptor sensitivity, and newer non-linear measures of HRV are described with a fair amount of mathematical detail with the biomedical engineer and mathematically oriented physician in mind. The book also covers two recent HRV methods, heart-rate turbulence and phase-rectified signal averaging. Use of HRV in Clinical Care The large clinical section is a must-read for clinicians and engineers wishing to get an insight into how HRV is applied in medicine. Nineteen chapters altogether are devoted to uses of HRV in: Monitoring-for example to predict potential complications in pregnancies, fetal distress, and in neonatal critical care Acute care-for gauging the depth of anesthesia during surgery and predicting change in patient status in the intensive care unit Chronic disorders-for assessing the severity of congestive heart failure, stroke, Parkinson's disease, and depression Bringing together the latest research, this comprehensive reference demonstrates the utility and potential of HRV signal analysis in both the clinic and physiology laboratory.

Advanced Cardiovascular Exercise Physiology, Second Edition, systematically details the effects of acute and chronic exercise training on each component of the cardiovascular system: the heart, the vasculature, and the blood (including blood clotting factors). Students and professionals working within exercise science and related health professions will gain a comprehensive understanding of the cardiovascular system and learn how to apply this knowledge to their work. Advanced Cardiovascular Exercise Physiology, Second Edition, highlights the complex interaction of the components of the cardiovascular system, both at rest and during exercise. Using the latest scientific and medical research, this text presents an engaging discussion of cardiovascular responses and adaptions to both aerobic and resistance exercise training, and it offers readers possible future directions for research. Specific attention is paid to the beneficial effects of exercise and the mechanisms through which regular exercise promotes cardioprotection. The second edition incorporates new topics and expanded information on the following: Ventricular hypertrophy Central blood pressure and its measurement Pathophysiology of arterial stiffness and relevant measurement techniques Blood pressure during exercise and its clinical importance The effects of prolonged acute exercise on cardiac arterial and hemostatic function Endothelial function, including the impact of aging and sex, and potential mechanisms An individual's response and adaptation to both resistance training and aerobic training The second edition of Advanced Cardiovascular Exercise Physiology uses a larger format to showcase its richly illustrated contents. Updated figures and graphics visually elucidate physiological mechanisms to depict exercise responses and training adaptations. Each chapter begins with chapter objectives and ends with a summary to help students retain important content. Fifteen case studies are included in the text to showcase the application of chapter material. Key terms are boldfaced throughout the text and are defined at the end of each chapter. In addition, sidebars describe real-world examples and applications. This text is divided into two sections. The first section offers a concise explanation of the structure and function of each component of the cardiovascular system. In the second section, readers encounter a detailed discussion of the acute and chronic effects of aerobic and resistance exercise on cardiac function, vascular function, and hemostatic variables. Advanced Cardiovascular Exercise Physiology, Second Edition, provides a framework for understanding how the components of the cardiovascular system cooperate to support exercise and how those components adapt to and benefit from a systematic program of exercise training.

Coronary Atherosclerosis: Current Management and Treatment addresses the leading cause of death worldwide - coronary artery disease. Atherosclerosis has a broad range of disease manifestations depending on the degree of the stenosis, and the functional status of the coronary plaque and is a disease cardiologists manage every day. Prevalence of coronary artery disease is increasing as a greater number of people live longer and rising rates of obesity contribute to poor health.

This brand new title, written by a leading international team of Editors, addresses the pathophysiology of disease, established and novel diagnostic approaches (both invasive and non-invasive), treatment methodologies (including treatment algorithms), and differing perspectives on treatment including future therapies and long term outcomes. It includes every aspect of coronary artery disease and highlights the optimal treatment for different clinical scenarios. The inclusion of personal perspectives from key opinion leaders, full color images and ancillary video files make this a key resource.

Key topics include:

• Pharmacology of coronary artery disease (CAD)
• Up-to-date evidence on pathophysiology
• Non-invasive imaging
• Current evidence for risk stratification
• Invasive imaging/cutting edge technology
• Clinical decision making from masters in the field

Coronary Atherosclerosis: Current Management and Treatment provides a state of the art review of current knowledge to aid specialists, general physicians, and cardiologists in training, in the diagnosis, risk stratification, and management of patients with diverse presentations of coronary atherosclerosis.

Mitral regurgitation (MR) affects millions of patients worldwide. It is a progressive condition that can worsen when left untreated, possibly leading to compensatory remodeling of the left ventricle. This can result in reduced functional capacity, poor quality of life, repeat hospitalizations, and even death from heart failure. Open, arrested heart surgery has until now been the therapeutic treatment of choice. However, many high-risk patients cannot tolerate traditional heart surgery and continue to suffer from severe MR. In Percutaneous Mitral Leaflet Repair: MitraClip Therapy for Mitral Regurgitation, international experts discuss the clinical application of percutaneous mitral valve therapies for this subsect of patients, focusing on the MitraClip device. These new therapeutic developments will form an essential component of the interventional cardiologists' armamentarium in treating MR patients and will be of interest to every practicing cardiologist. Key topics include: An overview of the anatomy and pathophysiology of the mitral valvular complex and MR EVEREST trial outcomes, and the development of percutaneous edge-to-edge repair Updates on the global experience with this new therapy Patient selection and the role of percutaneous therapies for high-risk patients Echocardiographic guidance, including practical tips for the use of transesophageal echocardiography during a procedure Step-by-step techniques, plus tips and tricks for getting the best results for your patients Special considerations for treating the returning MR repair patient Discussion of the European experience since CE approval Future directions in percutaneous mitral valve therapies

This unique book provides clinicians and administrators with a comprehensive understanding of perioperative hemodynamic monitoring and goal directed therapy, emphasizing practical guidance for implementation at the bedside. Successful hemodynamic monitoring and goal directed therapy require a wide range of skills. This book will enable readers to: * Detail the rationale for using perioperative hemodynamic monitoring systems and for applying goal directed therapy protocols at the bedside * Understand the physiological concepts underlying perioperative goal directed therapy for hemodynamic management * Evaluate hemodynamic monitoring systems in clinical practice * Learn about new techniques for achieving goal directed therapy * Apply goal directed therapy protocols in the perioperative environment (including emergency departments, operating rooms and intensive care units) * Demonstrate clinical utility of GDT and hemodynamic optimization using case presentations. Illustrated with diagrams and case examples, this is an important resource for anesthesiologists, emergency physicians, intensivists and pneumonologists as well as nurses and administrative officers.

Thistext, as the tide states, is acompilationofpapersdevoted to the studyofath erosclerosis, hypertensionanddiabetes.Thesethree distinctdisease entities, although not entirely unrelated, are three ofthe most important disease conditions in the world today.As such, this volumeofresearch papers isofobvious medical impor tance.Thejustificationofthe energy, time and financial resources directed towards the studyofeachofthese three diseases requiressome discussion. The majority of papers amongst the three diseases that are discussed in this volume are dedicated to the studyofatherosclerosis.This is not by accident.Car diovasculardisease isthenumberonekillertodayintheworld. IntheUnitedStates almost61 millionAmericanshaveoneormoreformsofcardiovasculardisease.These diseases claimed nearly 1million lives in 1998 alone.Although approximately 80% ofthosewho dieofcardiovasculardisease are 65 yearsofageorolder, asignificant numberofpeople are killed by cardiovascular disease below the ageof65.Ather osclerotic heart disease in the eoronary vaseulature eausedapproximately million deaths in the United States in 1998.At least 12,400,000people are alive todayin the United States with a historyofmyocardial infarctions or ehest pain or both. Clearly, atherosclerotie disease inthe heart isamajormedicalproblem.This disease affeetsbothmenandwomen.Althoughmen are more likelyto experienee aheart attaekand are atgreater risk for eardiovaseular disease, more then ofthe people alive today with a historyofheart attacks or angina are females. As weIl, women whodo havemyoeardialinfarctionsare twice aslikely to diefromtheeventwithin afew weeks.Atheroscleroticvasculardisease isnotlimitedtojustthe heart.Anath erosclerotic ischemic event is the primary causeofstroke today.Although it isnot weIl appreciated, stroke is the number 3 killer inAmerica today and the leading causeofdebilitatingneurological damage.Atherosclerotic vascular disease therefore, has acostintermsofhuman life, qualityoflifeandfinancialburden today thatno otherdisease canmatch.Theseriousnessofthis medicalproblemdemands research attention."

COULD STATIN DRUGS ACTUALLY HARM YOU?
Despite the rosy picture painted in the ads of a miracle cure for high cholesterol and its attendant heart disease, the reality of taking statins may be far less pretty. Dr. Barbara H. Roberts, director of the Women's Cardiac Center at the Miriam Hospital in Rhode Island, discusses both the benefits and health risks of these popular drugs in this comprehensive guide that finally reveals the questionable science behind the research studies. This honest, patient-friendly appraisal of the most widely used medications in the world may shock you, but it may also save your life.
Offering clear-cut, easy-to-understand information in an easily accessible fashion, Dr. Roberts explains how to take the best possible care of your heart, including:
* The keys to maintaining cardiovascular well-being
* How to interpret your cholesterol numbers
* The frightening adverse effects of popular drugs
It is time to take charge of your heart health. Learn the facts behind the hype so that you can make informed decisions on a subject vital to your continued health. If you or someone you love either takes a statin or is considering doing so, you need to read this book.
Includes recipes for a delicious and heart-healthy diet, including Wasabi-Roasted Salmon, Pasta with Avocado Sauce, and Lemon-Pineapple Breakfast Muffins.

Clinical Physiology of the Venous System is a comprehensive overview of vein physiology.

- Presents data in the fields of venous physiology, pharmacology and venous diseases as well as the field of phlebology, which has seen rapid and important progress in the last decade.
- Recent developments in venous disorders are covered with regard to pathophysiology; most modern diagnostic methods and therapies.
- Venous tone regulation data is presented with a focus on neural; hormonal; local and myogenic control of venous smooth muscle. Special attention was paid to endothelium-derived vasoactive factors involved in the regulation of venous tone.
- Take home messages at the beginning of each chapter for quick review.
- List of key abbreviations used in the book.
- Well illustrated with teaching tables.
- Useful for any physician, researcher or student interested in vein physiology.

This text provides a comprehensive, state-of-the-art review of catheter based approaches to valve and aortic diseases. The scope encompasses involve all the current and upcoming transcatheter aortic valve technologies as well as mitral, pulmonary and tricuspid valve technologies. Aortic diseases including transcatheter repair of descending aneurysms are included and the upcoming technologies designed to repair aortic dissections, traumatic injury, and ascending arch stent repair are highlighted. Catheter Based Valve and Aortic Surgery will be a useful tool for cardiac and vascular surgeons, interventional cardiologists, general cardiologists, and clinicians and researchers with an interest in these exciting new developments in structural heart and vascular diseases.

Thrombolytic therapy is finally starting to reach patients in a variety of settings all over the world. Formerly in the domain of sub-specialists, thrombolytic therapy now rests in the realm of Emergency Medicine, Intensive Care, Vascular, and Neuro hospital Medicine physicians. Increasingly, non-neurologists use thrombolytic therapy. This is a significant advancement since the 2nd edition to Thrombolytic Therapy for Acute Stroke published, creating a significant need for a 3rd edition. Thrombolytic Therapy for Acute Stroke, 3rd edition will be a practical and thorough reference to all those caring for acute stroke patients. Extensively updated from previous editions, new data and cases will provide guidance to this most effective stroke treatment. This text will be of great interest to physicians, residents and advanced practice nurses who treat acute stroke patients.

Learn to interpret cardiac dysrhythmias and successfully treat patients! Huszar's ECG and 12-Lead Interpretation, 6th Edition uses a step-by-step approach to help you build skills in accurate rhythm interpretation, diagnosis, and clinical management. Correlating ECG interpretation with clinical signs and symptoms, the text begins with basic skills and progresses to more advanced concepts. Hundreds of ECG rhythm strips provide plenty of practice with identifying heart rhythms. Written by experienced EMS physician and educator Keith Wesley, this guide is also ideal for quick reference while on the job, anywhere from the emergency department to the back of an ambulance. Comprehensive review of heart rhythm interpretation reflects current ECC guidelines. Logical organization of material teaches the way in which readers learn specific skills - ECG components are presented first, followed by rhythm interpretation and then clinical applications. Coverage of both basic and advanced concepts incorporates the latest research developments and provides material pertinent to both beginners and experienced prehospital care providers. Recognition of various heart rhythms is promoted by their appearance on the ECG, correlated with the patient's clinical signs and symptoms. Patient care algorithms outline step-by-step management and treatment, correlating ECG interpretation with history and exam findings. Advanced-level treatment content includes complete thrombus formation, treatment, and management. Take-Home Points summarize each chapter, highlighting need-to-know information about the most important topics. Author's Notes provide tips on alternative diagnoses, possible complications of warning signs, normal variations, and more, allowing you to benefit from the author's decades of experience. Expert author Dr. Keith Wesley is a board-certified emergency medicine physician and has been involved in EMS since 1989. Learning features include chapter outlines, learning objectives, key terms, chapter review questions, quick-reference summaries of the key characteristics of each heart rhythm, Drug Caution boxes, and a glossary. NEW! Updated content includes the latest guidelines from the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care and also the International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. NEW! Updated learning features include key definitions, ECG Keys boxes, Take-Home Points, author's notes, chapter review questions, an appendix of more than 250 self-assessment rhythm strips, and an appendix of answers to the chapter review questions.

This second edition of the Transesophageal Echocardiography Multimedia Manual is a comprehensive resource and essential guide to the rapidly expanding field of perioperative transesophageal echocardiography (TEE), encompassing newer cardiac surgery techniques, more diverse surgical procedures, and use in the intensive care unit. With over 900 figures, this well-illustrated manual and its accompanying videos and self-test questions demonstrate new developments and challenges for the anesthesiologist, cardiologist, cardiac surgeon, critical care physician, and those interested in perioperative TEE. The accompanying downloads present two-dimensional examples in their original video format accompanied by sketches, three-dimensional orientation, Doppler-related information, and hemodynamic, radiologic, and anatomical correlation to assist the user visualize the dynamic process of transesophageal echocardiography. New to this edition! Now in full-color with over 800 pages of content, including six new chapters covering new minimally invasive cardiac surgical techniques, non-cardiac surgery, and complementary imaging techniques such as three-dimensional echocardiography plus updates to all existing chapters Over 900 high-resolution images to illustrate the advancement of echocardiography technology Companion downloads showcase over 1000 videos of 2-dimensional examples accompanied by 3-dimension orientation providing an interpretation of results, plus over 140 self-test questions Expert perspectives from over 85 renowned and experienced anesthesiologists, cardiologists, cardiac surgeons, and critical care physicians from five countries

This new title provides a systematic review of complex cases in peripheral vascular interventions (PVI), a minimal invasive endovascular approach to treating peripheral arteries. This increasingly evolving area in interventional therapies offers reduced risk for complications compared to conventional surgery and takes advantage of advanced techniques to treat more complex lesions in severely diseased patients.

This book edited by two highly respected professors from the University of Vienna, Medical School describes typical and atypical complex cases for all peripheral vessel areas, and outlines methods to successfully and safely handle these interventions. The text is divided into two sections. The first reviews general aspects on managing complex patients in PVI, and the second discusses complex cases in specific vessel areas, examining the interventions from puncture to closure, head to toe. Each of the chapters in this section is further divided into three parts and provides:

• An introduction to each vessel, specific information on the complexities of this lesion and the hazards of treatment, and a checklist for readers of recommended equipment when treating this specific vessel area
• Selected teaching cases, whereby specific vessel areas are described step-by-step
• A summary of the key issues for the successful and safe treatment of complex lesions in this vessel area.

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Complex Cases in Peripheral Vascular Interventions offers readers the opportunity to tap into the knowledge of those working on complex cases in this cutting edge field and receive both theoretical information and practical tips on how to approach specific vascular lesions. This book is a highly recommended read for beginners in endovascular interventions who want to get an impression on the advanced scope of treatment options as well as for experienced interventionists who want to extend their knowledge on difficult cases.

During last two decades, stress echocardiography has progressed from a promising idea to a crucial diagnostic and prognostic tool in various cardiac conditions, particularly in ischemic heart diseases. Written by world recognized experts in the field, Stress Echocardiography: Essential Guide is an all-inclusive source of key information related to the principles and practice of stress echocardiography. Both the stress echocardiography trainee and those in practice seek to benefit from this text and downloadable resources set. Important features include: user-friendly downloadable resources over 500 color and black-and-white illustrations and tables to assist the reader in correctly identifying various disease states detailed list of 50 landmark papers with commentary presentation of difficult case studies from everyday practice exploration of the practical aspects of imaging during stress and the science of reading of stress echo studies detailed explanations of the quantification of echocardiographic response and stress echo interpretation descriptions of the use of different stress echocardiographic modalities in specific clinical situations, as well as the advantages, drawbacks, pitfalls, and implications of results on patient management

This second edition brings together a variety of method used in the field of cardiovascular development research. Chapters guide readers through protocols on lymphatic development, lymphatic staining techniques, lymphatic endothelial, tissue clearing techniques, and muscle cell isolation and culture. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls Authoritative and practical, Cardiovascular Development: Methods and Protocols, Second Edition seeks to aid scientists in understanding new state-of-the-art techniques in the field of cardiovascular development research.