This issue of Cardiac Electrophysiology Clinics, Guest Edited by Drs. Giuseppe Bagliani, Roberto De Ponti, and Fabio Leonelli is dedicated to The Complex World of Cardiac Pre-Excitation: towards Precision Electrocardiology. This is one of four issues selected each year by the series Consulting Editors, Ranjan K. Thakur and Andrea Natale. Topics include, but are not limited to, Anatomy of the AV junction, Pre-excitation, Algorithms to identify accessory pathways location on 12-lead ECG, Pathophysiology of accessory pathways-mediated arrhythmias, Arrhythmias with by-stander accessory pathways, Arrhythmias involving unusual accessory pathways, Sudden cardiac death in patients with ventricular pre-excitation, Clinical approach to symptomatic and asymptomatic patients with ventricular pre-excitation, Methodology of accessory pathway ablation, Ablation of accessory pathways with unusual anatomic location, Ablation of accessory pathways with uncommon electrophysiologic properties, and Ablation in pediatric patients and in association with congenital heart disease.

The topic of heart failure although extensively researched and reported, has several gray areas. This is especially seen in determining strategies for combating advanced heart failure. The global burden of ischemic heart disease is increasing at an alarming rate to almost pandemic proportions. Even in the presence of state-of the art technology for prompt and successful coronary reperfusion, the population progressing to ischemic cardiomyopathy is substantial. The treatment strategies for ischemic cardiomyopathy do not always ensure optimal clinical results, the reasons for which are varied. The proper patient selection is vital as is the tailoring of suitable therapy. The approach is thus multi-pronged, of which surgical ventricular restoration (SVR) has a definite role. Despite various randomized studies like the STICH-hypothesis 2, where there was a huge selection bias, with patients subjected to an erroneous technique of SVR, with inadequate ventricular remodelling assessment. The present need is to understand the unique anatomy of the left ventricle, its function and perturbations with the onset of heart failure, in order to plan therapeutic strategies to restore near normal anatomy and function. A study of the hemodynamics in ischemic cardiomyopathy is essential, as it differs in certain aspects from other causes of heart failure like idiopathic dilated cardiomyopathy and valvular heart diseases. Since information on these aspects are scattered in various scholarly articles, a concise source in the form of a book would be appropriate and useful for both cardiologists and cardiac surgeons. This project represents a concise review of normal and abnormal cardiac anatomy and physiology, the evolution of SVR to EVLPP with validation of near normal ventricular restoration, plus act as a reference guide for cardiac surgeons with interest in SVR.

This book aims to clarify the potential association between frailty and cardiovascular disease in older people. Covering the biological as well as the clinical point of view, it allows researchers and clinicians to discover the significance of this topic. The contributions cover the most important aspects in the potential relationship between frailty and cardiovascular disease. In particular, authoritative authors in this field have clarified the definition and the epidemiology of frailty and cardiovascular disease in older people. A large part of the volume is dedicated to the biological mechanisms of frailty and cardiovascular disease, trying to find those in common between these two conditions. Since this book is dedicated to both researchers and clinicians, we have proposed some chapters to the importance of comprehensive geriatric assessment in the evaluation and treatment of cardiovascular diseases and frailty. In this regard, the importance of geriatric evaluation in cardiac surgery for older people is well covered. Finally, the importance of cardiac rehabilitation and physical exercise is summarized, being, actually, the most important treatments for both frailty and cardiovascular disease. Written by many well-known and widely published experts in their respective fields, this book will appeal to a wide readership such as researchers in the field and clinicians, especially suited in geriatric medicine and cardiology who, every day, face frail older patients.

With a step-by-step method for accurate interpretation of the ECG, this third edition of Rapid ECG Interpretation describes a systematic approach consistent with the changes in cardiology practice over the past decade. All diagnostic ECG criteria are given with relevant and instructive ECGs, providing a quick review or refresher for proficiency tests and for physicians preparing for the ECG section of the Cardiovascular Diseases Board Examination. This edition contains over 320 ECGs and instructive illustrations, including 81 new ECG tracings. Clear and concise 11-step methods are set out in a user-friendly synopsis format.

This issue of Interventional Cardiology Clinics, guest edited by Dr. Hitinder Gurm, will discuss Renal Disease and coronary, peripheral and structural interventions. This issue is one of four selected each year by the series Editor-in-Chief, Dr. Matthew Price. Topics discussed in this issue will include: Contrast induced nephropathy, Pathophysiology of CIN, Implications of Renal disease in patients undergoing peripheral arterial interventions, Implications of renal disease in patients undergoing Structural interventions, Different types of contrast media, Biomarkers of CIN, Pharmacological prophylaxis of CIN, A practical approach to preventing renal complications in the catheterization laboratory, and several other topics.

A cutting-edge review of the latest findings on key scientific topics and the best strategies for evaluation and management of portal hypertension in the clinic. Writing in an easy-to-read style, the authors review its pathobiology, the progress being made in its experimental understanding, the methodologies to assess it in humans, the treatment of its complications (esophageal varices, ascites, and hepatorenal syndrome), and its treatment in special circumstances (during pregnancy, in children, or when the portal vein is blocked). They also provide in-depth coverage of the pros and cons of the various therapeutic choices available to the clinician managing patients with complicated portal hypertension.

Do you suffer from heart palpitations and arrhythmias (and you think you are otherwise healthy), or do you want to prevent clogged arteries and other heart disease? Perhaps you are one of millions who are saddled with over-prescribed cholesterol, blood pressure, and blood thinning medications. Either way, Keeping Your Heart in Rhythm uncovers many unknown facts about heart ailments and heartbeat irregularities and provides safe, natural, and inexpensive ways for you to control all the above issues. Author Stuart B. Kalb, a healthcare, estate planning, elder law and former trial attorney for over thirty years, dissects complicated medical terminology and, in turn, offers concise and easily comprehendible ways you can: * Conquer heartbeat irregularities * Eliminate high cholesterol * Lower blood pressure * De-plaque your arteries * Alleviate and avert potentially fatal blood clots * Reduce the risk of stroke and cardiovascular disease You will learn how you can experience higher energy levels and less stress over your physical well-being without expensive and harsh drugs, invasive procedures, and surgery.You will never again suffer horrific side effects from medicine, but you will in

In collaboration with the Consulting Editors, Ranjan K. Thakur and Andrea Natale, Drs. Luigi Di Biase, Frank Marchlinski, and Andrea Natale have assembled an issue of Cardiac Electrophysiology Clinics on Advances in Atrial Fibrillation Ablation. Topics include, but are not limited to, Recurrent atrial fibrillation with isolated PVs, Beyond PVI in non paroxysmal atrial fibrillation, Recurrent atrial fibrillation after cryo, Recurrent atrial fibrillation after RF, high-density mapping, Expectation and Results of surrogate target beyond PVI, Lessons from epicardial mapping and ablation in refractory atrial fibrillation, Evolution of radiofrequency ablation parameters, Balloon based technologies, Energy sources, Current status of esophageal protection, Fluoroless atrial fibrillation ablation, Role of MRI imaging before and after ablation, When to stop OAC after atrial fibrillation ablation, Atrial fibrillation ablation trials, Risk Factor modification before and after atrial fibrillation ablation.

Dr. Perloff, the founding father of the field of adult congenital heart disease, presents a decade's worth of research and clinical data in the completely redefined 3rd edition to bring you the most current information. With advances in diagnosis and treatment in children, more and more of those with CHD survive well into adulthood. Expert contributors in various fields offer a multi-disciplinary, multi-system approach to treatment so you get comprehensive coverage on all aspects of the subspecialty, including basic unoperated malformations, medical and surgical perspectives, postoperative residue, and sequelae. As someone who treats these patients, you need to be ready to provide the continual care they require. Conveys a multidisciplinary, multi-system approach to the lifelong care of adult CHD patients to put treatment in a broader context. Presents information in a consistent, logical style so the information you need is easy to find and apply. Supplements the text with 600 clear conceptual illustrations to clarify difficult concepts. Features completely rewritten chapters to include the latest developments in the field-such as major advances in surgical and interventional techniques-and the various needs of patients with adult CHD. Incorporates recently published trials such as those involving cyanotic CHD and atherogenesis, coronary microcirculation, and pathogenesis of thrombocytopenia to supplement the chapter on cyanotic CHD. Emphasizes advances in imaging in a new section-edited by an expert-that covers echocardiography as well as specialized imaging techniques. Illustrates the full range of advances in the field with 600 images that reflect the latest progress. Includes new chapters-Global Scope of ACHD; Cardiac Transplantation; Electrophysiologic Abnormalities in Unoperated Patients and Residue and Sequelae After Cardiac Surgery-to provide you with the latest information on the growth of the subspecialty and its effect on treatment. Presents revisions by a new authorship of experts in infectious disease, genetics and epidemiology, sports medicine, neurology, cardiac surgery, cardiac anesthesiology, and more.

This book provides clinical tips on management of catastrophic emergencies that are regularly faced by critical care and acute care cardiologists in resource-limited settings. Based on the current guidelines, it explores the evaluation of the patient, followed by its treatment methodology. It highlights the beneficial effects of the use of cardiac drugs during an emergency. There is also a special section on preoperative evaluation and postoperative management of cardiac patients of different subsets. Medicolegal/documentation points have also been discussed where relevant. It is useful as a ready reference for physicians, anaesthetists and cardiologists. Key features: • Reinforces certain teachings and recalls certain overlooked clinical points to address emergency situations in a busy, resource limited setting. • Explains lucidly what the acute cardiac care / Anesthesia registrar or cardiology fellows ought to do in the Intensive care and Post operative wards. • Emphasizes the importance of wit, clinical acumen and observation.

This issue of Heart Failure Clinics, guest edited by Giovanni Esposito and Michinari Hieda, will cover key topics in Cardiovascular Emergencies. This is part one of a two-part issue and is one of four issues selected each year by our series consulting editor, Dr. Eduardo Bossone. Topics discussed in this issue will include: Case Report in the ER, Case Report in the ICU, Acute and Chronic Effects of Cancer Drugs on the Cardiovascular System, Acute Mitral Regurgitation and Mitral Clip in an Emergency Case, Acute Decompensated Heart Failure in Patients with Heart Failure with Reduced Ejection Fraction, Echocardiography Tips in the ER, Acute Myocardial Infarction in Left Main Trunk, Complicated Advanced Heart Failure, Palliative Care in Patients with Advanced Heart Failure, among others.

Patients with peripheral vascular disease (PVD) are at increased risk of death when compared with age-matched healthy controls. They are also, whether symptomatic or not, six times more likely to die within ten years when compared to patients without the disease. This excess mortality exists even if coronary artery disease is not clinically present, and makes the treatment of PVD a highly important and pressing topic. In this fully up-to-date text, Dr. Mukherjee and his excellent team of twenty-one contributors present the reader with all of the currently available clinical information for treating PVD patients effectively.

Highly useful guide for all members of a multidisciplinary team managing children suffering from heart disease Built on the success of previous editions and brought to you by a stellar author team, Moller's Essentials of Pediatric Cardiology, 4th Edition provides a unique, concise, and extremely practical overview of heart disease in children. From history-taking, physical examination, ECG, and chest X-ray-the basics that enable clinicians to uncover possible problems and eliminate areas of false concern-this work goes on to examine the range of more complex topics in the diagnosis and treatment/management of childhood cardiovascular disease. Every chapter is fully updated with the very latest clinical guidelines and management options from the AHA, ACC, and ESC. Recent updates also include an enhanced section on imaging, including recent advances in cardiac MRI and fetal echocardiography, new techniques in genetic testing for heart disease in special populations, and much more emphasis on the importance of echocardiography in understanding the pathophysiology of congenital cardiac malformations. This work also includes an expanded section on cardiac conditions in the neonate, specifically on prenatal diagnosis and management, and neonatal screening for congenital heart disease. Moller's Essentials of Pediatric Cardiology, 4th Edition also provides: Tools to diagnose cardiac conditions in children and environmental and genetic conditions associated with heart disease in children Anomalies with a left-to-right shunt in children, conditions obstructing blood flow in children, and congenital heart disease with a right-to-left shunt in children Unusual forms of congenital heart disease in children, unique cardiac conditions in newborn infants, and the cardiac conditions acquired during childhood Abnormalities of heart rate and conduction in children and congestive heart failure in infants and children Moller's Essentials of Pediatric Cardiology, 4th Edition is a succinct and accessible yet highly detailed and informative resource for treating children suffering from heart disease. It is an invaluable reference for anyone working on a multidisciplinary team treating patients with these attributes.

Injured mammalian hearts do not regenerate but scar. This is a major medical problem, as ischemic heart disease is among the leading causes of morbidity and mortality worldwide. Essential clues for human heart repair are uncovered when zebrafish and newt are found to regenerate cardiac muscle after injury. This book presents the major advances of the last decade in the field of cardiac regeneration. These recent advances include: demonstration that zebrafish, a genetically tractable system, can regenerate heart; the identification of several new stem cell populations in the heart; demonstration that stem cells can be used to improve heart function; and demonstration that induction of cardiomyocyte proliferation is a realistic future option to repair injured hearts. This book also provides detailed reviews of the research on model organisms capable of heart regeneration as well as innovative translational research to achieve regeneration in mammals, that comprises work on blood born stem cells, endogenous cardiac stem cells, paracrine factors, reawakening of cardiomyocyte proliferation, and bioengineering. More importantly, the book, in the concluding chapter, dovetails the studies with a comprehensive overview of clinical trials.

This issue of Cardiology Clinics will cover Right Ventricular Function and Failure. Curated by Drs. Jerry D. Estep and Miriam Jacob, this issue will explore topics in the field that are relevant for practicing clinicians. This issue is one of four selected each year by the series editorial board: Jamil A. Aboulhosn, David M. Shavelle, Terrence D. Welch, and Audrey H. Wu. The volume will include articles on: pathophysiology of acute and chronic right heart failure, right heart failure: a hemodynamic review, right heart failure causes and epidemiology, right heart failure and the cardiorenal syndrome, the role of multimodality imaging and RV failure, short term percutaneous mechanical circulatory support to treat acute right heart failure, defining and predicting right heart failure after LVAD placement, right heart failure after LVAD placement: medical and surgical management considerations, right heart failure in pulmonary hypertension, surgical and percutaneous interventions for chronic thromboembolic pulmonary hypertension, pulmonary hypertension and RV failure: lung transplant versus heart lung transplant, and RV failure and congenital heart disease.

For every physician that interprets ECGs, there is great need to understand a vast amount of information regarding the technique. That the basics of the technique have changed little over the last 100 years means that there is a huge amount of subtle detail that must be learnt to enable its effective use as a diagnostic test. The ECG technique is critical for deciding upon further diagnostic procedures and therapeutic interventions (notably coronary angiography, PTCA, stenting, coronary artery bypass grafting, pacemaker insertion, ablation, electroconversion etc). Without attaining the skills to practice the ECG procedure and knowledge of its diagnostic value - skills often overlooked during medical training - physicians will be unlikely to use it to the benefit of their patients.

Chronic total occlusions (CTO) are common, and found in approximately one third of patients with significant coronary artery disease who undergo angiography. CTO constitute one of the main criteria when selecting between angioplasty and bypass surgery. Angioplasty for CTO is intricate and requires excellent operator skill, but even when performed under the best circumstances, it is plagued by lower success rates when compared to non-total occlusions. The main difficulty with CTO lies not with choosing which stent to use, but rather occurs during earlier steps of crossing the lesion and advancing the wire into the true lumen of the distal vessel. Having accomplished this, the rates of restenosis are prohibitively high. Mehran, Dangas and an international team of experienced operators offer the reader sound advice on the evaluation and management of CTO in both the coronary and peripheral vascular systems. Their practical guidance should aid all those working with this difficult subset of patients.

Cardiac disease is one of the leading causes of maternal morbidity and mortality. Catastrophic outcomes typically encountered are due to gaps in knowledge and communication between health care providers. There is a great need for a standardized approach for care of this very high-risk group of pregnant women. The book encompasses detailed obstetrics and cardiology perspectives that are crucial in the management of the commonly encountered cardiac conditions in pregnancy. This text aims to provide guidance to the whole team caring for a pregnant cardiac patient consisting of obstetricians, maternal-fetal medicine, hospitalists, cardiologists, obstetric anaesthesiologists, emergency physicians, primary care providers and nurses. Features: Cardio-Obstetric team organization Preconception counselling and family planning considerations Cardiovascular disease screening and risk stratification of a pregnant cardiac patient Management of a wide spectrum of cardiovascular diagnoses through use of checklists and algorithms in a simple format Essential key points for each cardiac diagnosis

Promoting developments in the diagnosis, prevention, and treatment of coronary artery disease, this reference furnishes the latest information on new and emerging risk factors for atherothrombotic vascular disorders-analyzing lipid-related and psychosocial risk factors, the genetic aspects of disease, the potential role of infection and inflammation, metabolic syndrome and insulin resistance, and elevated blood levels of homocysteine and hemostatic factors.

Fully updated from cover to cover, Zipes and Jalife's Cardiac Electrophysiology: From Cell to Bedside, 8th Edition, provides the comprehensive, multidisciplinary coverage you need-from new knowledge in basic science to the latest clinical advances in the field. Drs. Jose Jalife and William Gregory Stevenson lead a team of global experts who provide cutting-edge content and step-by-step instructions for all aspects of cardiac electrophysiology. Packs each chapter with the latest information necessary for optimal basic research as well as patient care. Covers new technologies such as CRISPR, protein research, improved cardiac imaging, optical mapping, and wearable devices. Contains significant updates in the areas of molecular biology and genetics, iPSCs (induced pluripotent stem cells), embryonic stem cells, precision medicine, antiarrhythmic drug therapy, cardiac mapping with advanced techniques, and ablation technologies including stereotactic radioablation. Includes 47 new chapters covering both basic science and clinical topics. Discusses extensive recent progress in the understanding, diagnosis, and management of arrhythmias, including new clinical insights on atrial fibrillation and stroke prevention, new advances in the understanding of ventricular arrythmias in genetic disease, and advances in implantable devises and infection management. Features 1,600 high-quality photographs, anatomic and radiographic images, electrocardiograms, tables, algorithms, and more., with additional figures, tables, and videos online. Recipient of a 2018 Highly Commended award from the British Medical Association. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

In collaboration with the Consulting Editors, Ranjan K. Thakur and Andrea Natale, Drs. David R. Holmes Jr., Saibal Kar, Dhanunjaya Lakkireddy, and Vivek Reddy have assembled an issue of Cardiac Electrophysiology Clinics on Left Atrial Appendage. Topics include, but are not limited to, why we have an atrial appendage, thromboembolism in AF, role of LAA in systemic homeostasis, history of LAA closure, impact of LAA closure on systemic thromboembolization, perirprocedural imaging, anatomical considerations for epicardial and endocardial appendage closure, epicardial vs endocardial closure, technical considerations of endocardial and epicardial closure, surgical LAA occlusion, post procedural management, AF patients undergoing ablation, and more.

Medical Semiology Guide of the Cardiovascular System and the Hematologic System provides a comprehensive understanding of medical semiology in the cardiovascular and hematologic systems. Highly illustrated with many original images from the author's daily medical practice, the book highlights all signs of diseases and important semiological maneuvers in the field. Each chapter incorporates a specific questionnaire with important questions that should be asked to patients in different situations to obtain valuable information that helps identify rare and unusual diseases. This unique feature of the book aims to facilitate the learning process among medical students, while also acting as a quick reference for clinicians.

"Cardiology: Clinical Cases Uncovered" is the ideal integrated text to help you recognize, understand and know how to investigate and manage many heart-related disorders and conditions. Written by three practising cardiologists, it leads students through a clinical approach to managing problems with 26 real-world cardiovascular cases. There is strong emphasis on high-quality figures, particularly 12-lead ECGs, as these play such a major role in the evaluation of the cardiac patient.

Following a question-answer approach throughout the narrative, with self-assessment MCQs, EMQs and SAQs, "Cardiology: Clinical Cases Uncovered" includes sections on cardiac anatomy, physiology and pathology which provide the essentials required to understand clinical cardiology, and is ideal for medical students and junior doctors on the Foundation Programme, specialist nurses and nurse practitioners, and for those with plans for a career in cardiology.