Inflammation and Natural Products brings together research in the area of the natural products and their anti-inflammatory action in medical, nutraceutical and food products, addressing specific chronic inflammatory diseases like cancer and the mechanistic aspects of the mode of action of some key natural products. Inflammation is a complicated process, driven by infection or injury or genetic changes, which results in triggering signalling cascades, activation of transcription factors, gene expression, increased levels of inflammatory enzymes, and release of various oxidants and pro-inflammatory molecules in inflammatory cells. Excessive oxidants and inflammatory mediators have a harmful effect on normal tissue, including toxicity, loss of barrier function, abnormal cell proliferation, inhibiting normal function of tissues and organs and finally leading to systemic disorders. The emerging development of natural product formulations utilizing the unique anti-inflammatory compounds such as polyphenols, polysaccharides, terpenes, fatty acids, proteins and several other bioactive components has shown notable successes. Inflammation and Natural Products: Recent Development and Current Status provides a comprehensive resource, ranging from detailed explanation on inflammation to molecular docking strategies for naturally occurring compounds with anti-inflammatory activity. It is useful for graduate students, academic and professionals in the fields of pharmaceutical and medical sciences and specialists from natural product-related industries.

COULD STATIN DRUGS ACTUALLY HARM YOU?
Despite the rosy picture painted in the ads of a miracle cure for high cholesterol and its attendant heart disease, the reality of taking statins may be far less pretty. Dr. Barbara H. Roberts, director of the Women's Cardiac Center at the Miriam Hospital in Rhode Island, discusses both the benefits and health risks of these popular drugs in this comprehensive guide that finally reveals the questionable science behind the research studies. This honest, patient-friendly appraisal of the most widely used medications in the world may shock you, but it may also save your life.
Offering clear-cut, easy-to-understand information in an easily accessible fashion, Dr. Roberts explains how to take the best possible care of your heart, including:
* The keys to maintaining cardiovascular well-being
* How to interpret your cholesterol numbers
* The frightening adverse effects of popular drugs
It is time to take charge of your heart health. Learn the facts behind the hype so that you can make informed decisions on a subject vital to your continued health. If you or someone you love either takes a statin or is considering doing so, you need to read this book.
Includes recipes for a delicious and heart-healthy diet, including Wasabi-Roasted Salmon, Pasta with Avocado Sauce, and Lemon-Pineapple Breakfast Muffins.

The Understanding Angina chart is a detailed overview of the types, causes, symptoms and treatment options of angina. Images include external views of a damaged heart, showing ischemia and a narrowed artey, and the heart's blood supply. Heavy gauge 3ml lamination with sealed edges and two metal eyelets for hanging makes chart highly durable. Write-on/wipe-off with dry erase marker (not included).

This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.

This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.

This extension to the popular "ECGs for the Emergency Physician Volume 1 "continues to provide the emergency health care provider with outstanding practical and emergency medicine-relevant teaching of a life-saving skill: emergency electrocardiography interpretation.

This volume can be used individually or paired with Volume 1 to present one of the most comprehensive and educational ECG collections ever assembled for emergency physicians and other acute health care providers.

Wolff-Parkinson-White Syndrome (WPW) is recognized as an abnormality of cardiac rhythm that manifests as supraventricular tachycardia. Few practitioners today appreciate how much the development of clinical cardiac electrophysiology owes to Wolff-Parkinson-White Syndrome. In the early 1960s, it became the test bed for electrophysiological theory and new therapies. Surgical electrophysiological techniques were developed, the pathways were severed, and the patient was often left with an entirely normal heart. This was an important first in modern cardiology - a complete cure. The aim of the Clinical Approaches to Tachyarryhthmias series is to update the physician, cardiologist, and all those responsible for the the care of patients with cardiac arrhythmias. In this volume, the authors unfold the story of WPW, its precise diagnosis by use of electrocardiography, its successful management and its near extinction in parts of the world reached by modern medical technology, and the remaining challenge it represents in pediatric medicine and in other parts of the globe.

Reviews of previous editions: "...a well conceived practical guide to the interpretation and treatment of the main cardiac rhythm disturbances." Lancet "This book presents a concise and simplified approach to the diagnosis and management of abnormalities in cardiac rhythm...One of the book's strengths is the number and quality of electrocardiographic tracings" New England Journal of Medicine "...this book provides an excellent foundation for all those involved in the care of arrhythmia patients" British Journal of Hospital Medicine " would recommend it unreservedly to anaesthetists who wish to improve their knowledge of cardiac arrhythmias" British Journal of Anaesthesia "This book about cardiac arrhythmias is of much educational value" European Heart Journal A trusted source for junior doctors, students, nurses and cardiac technicians for over 30 years, the new edition of this classic reference continues the winning formula of previous editions while at the same time incorporating essential new content on today's most important clinical topics, including: * Atrial fibrillation: ablation, drugs, rate control versus rhythm control, risk of systemic embolism, prognosis * Indications for and management of implantable defibrillators including complications such as arrhythmia storms * Indications for pacemaker implantation * Anticoagulant therapy (for atrial fibrillation) * Long QT syndromes and other channelopathies * Recently-approved anti-arrhythmia drugs The 8th edition also features the latest guidelines on ECG screening of athletes and clear guidance for anaesthetists and surgeons dealing with patients with arrhythmias an/or implantable devices. Rich with example ECGs and designed for ease of access to information, Bennett's Cardiac Arrhythmias is the reference you can trust to help you master arrhythmia diagnosis and provide optimal treatment of any patient under your care.

Hemodynamic monitoring is one of the major diagnostic tools available in the acute care setting to diagnose cardiovascular insufficiency and monitor changes over time in response to interventions. However, the rationale and efficacy of hemodynamic monitoring to affect outcome has come into question. We now have increasing evidence that outcome from critical illness can be improved by focused resuscitation based on existing hemodynamic monitoring, whereas non-specific aggressive resuscitation impairs survival. Thus, this book frames hemodynamic monitoring into a functional perspective wherein hemodynamic variables and physiology interact to derive performance and physiological reserve estimates that themselves drive treatment. This philosophy, as well as the limitations and applications of common and evolving hemodynamic measures and their focused use in the care of critically ill patients are discussed, relevant to one underlying truth: No monitoring device, no matter how simple or sophisticated, will improve patient-centered outcomes useless coupled to a treatment which, itself, improves outcome.

Sitting an accreditation examination is a daunting prospect for many trainee echocardiographers. And with an increasing drive for the accreditation of echocardiography laboratories and individual echocardiographers, there is a need for an all-encompassing revision aid for those seeking accreditation. The editors of this unique book have produced the only echocardiography revision aid based on the syllabus and format of the British Society of Echocardiography (BSE) national echocardiography accreditation examination and similar examinations administered across Europe. Written by BSE accredited members, fully endorsed by the BSE, and with a foreword by BSE past-president, DR. Simon Ray, this indispensable guide provides a valuable insight into how echocardiography accreditation exams are structured. Crucially, to support students with the more challenging video section of the exam, a companion website provides video cases, and with clear and concisely-structured explanations to all questions, this is an essential tool for anyone preparing to sit an echocardiography examination.