Key Clinical Topics in Cardiology presents a brand new addition to the Key Clinical Topics series. The book provides a comprehensive overview of the subject, comprising over 60 carefully selected topics in alpha order that together provide an extensive understanding of the management of cardiovascular disorders. This collection of highly practical guides systematically addresses management techniques for a large number of clinical settings. Edited by experienced specialists, with contributions from consultants who have recognised expertise in their field, this book provides an authoritative and up-to-date guide on cardiovascular medicine. Designed to enable rapid access to core information, KCT Cardiology offers effective exam revision and the ideal quick reference for day-to-day practice. Key points Over 60 topics presented in alpha order, from acute advanced life support to tumours Effective exam revision for postgraduate trainees in cardiology preparing for certification Succinct coverage of cardiac treatment modalities and complications Includes clinical photos and diagrams to improve understanding of concepts Contributions from experienced specialists to ensure authoritative, accurate content

The latest edition of this practical handbook provides a concise yet comprehensive overview of common and rare problems with hemostasis and thrombosis. Through thoroughly updated and revised chapters, the text features practical information on diagnosing and managing troublesome hematologic conditions often found in clinical practice. The handbook also spotlights advances in the field since the publication of the last edition, including multiple novel coagulation factors for hemophilia, the increasing use of novel anticoagulants and their reversal agents, and the increasing use of genetics for diagnosis. Written by experts in the field, Hemostasis and Thrombosis, Fourth Edition is an invaluable resource for healthcare professionals who treat patients afflicted with these conditions.

* Tom Kenny, one of the best-known and well-respected educators in EP brings his signature style to this new primer * Practical, accessible, highly illustrated approach makes learning easy * Provides an overview of the algorithms and devices offered by the world s five pacemaker manufacturers * Offers clinicians learning objectives, test questions and essential points in bulleted lists * Perfect introductory guide to the topic, assumes little baseline knowledge and appropriate for residents, fellows, EP nurses, general clinical cardiologists, EP fellows and industry professionals

This comprehensive resource brings together the most current theories, evidence and best practice parameters for the use of nocturnal non-invasive ventilation (nNIV). Chapters focus on the application of acute and chronic nNIV in patients with cardio-respiratory disorders over a range of major medical settings. Updates on past and recent research in this field are highlighted. Authored by leading clinicians and investigators, Nocturnal Non-Invasive Ventilation provides practical and cutting-edge knowledge to physicians, researchers and allied health professionals on the front lines of treating cardio-respiratory and sleep disorders.

In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize

Advanced Hematology in Integrative Cardiovascular Chinese Medicine, volume three in the Integrative Cardiovascular Chinese Medicine series, systematically observes and discusses laboratory tests which detect heart diseases and analyzes the results. It includes coverage of red and white blood cell homeostasis and advanced anatomy and physiology of the vascular system, including the biomedicine perspectives of blood and lymphatic system, and TCM perspectives of essence, qi, blood and body fluid. In addition, the book examines the immune system from the perspective of Traditional Chinese Medicine, including pestilential differentiation. Case studies, lab charts and laboratory differentials according to Chinese and Western medicine perspectives are also included. Finally, the book discusses the use of lab results for assisting and/or confirming diagnoses of blood and cardiovascular disorders in both Traditional Chinese Medicine and Western medicine. This important reference will aid cardiovascular researchers in the study of integrative Chinese and Western medicine with its clear, structured base to guide clinical practice and encourage collaboration.

Herbal, Bio-nutrient and Drug Titration According to Disease Stages in Integrative Cardiovascular Chinese Medicine, the first volume in the Integrative Cardiovascular Chinese Medicine series, provides a comprehensive guide to improving outcomes with cardiovascular medicine therapy options. Coverage includes the three types of medicines used in disease stage treatment, Chinese medicine, nutritional supplements and pharmaceutical drugs. All sections are organized according to drug class in western medicine and chapters in each section are organized according to disease stage, providing ease in navigation and reference within the book. This important reference will aid cardiovascular researchers in the study of integrative Chinese and western medicine as well as provide a clear, structured base to guide clinical practice and encourage collaboration between Chinese and Western medicine practitioners.

Echocardiography remains the most commonly used imaging technique to visualize the heart and great vessels, and this clinically oriented text by Drs. Scott D. Solomon, Justina C. Wu, and Linda D. Gillam helps you make the most of its diagnostic and prognostic potential for your patients. Part of the highly regarded Braunwald's family of cardiology references, Essential Echocardiography expertly covers basic principles of anatomy and physiology, the appearance of normal variants across a wide range of cardiovascular diseases, and the hands-on approaches necessary to acquire and interpret optimal echocardiographic images in the clinical setting. Abundant illustrations provide a superb visual learning experience both in print and online. Images convey clear, classic examples that represent decades of experience over multiple institutions, as well as recent advances in the field. More than 485 accompanying video clips mirror the images in the text, with easy-to-follow links from the figure citation to the video online. Each section includes one or two clinical cases that illustrate key concepts. Written by expert echocardiographers and sonographers who emphasize practical applications throughout the text, and superbly illustrated by physician-artist Dr. Bernard Bulwer. Ideal for anyone currently using or learning to use echocardiography, including cardiologists, cardiology fellows, sonographers, anesthesiologists, critical care physicians, emergency physicians, radiologists, residents, and medical students. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Elevated homocysteine is a powerful, independent risk factor in more than 100 major medical conditions, including heart disease, strokes, and Alzheimer's disease. The authors discuss factors that contribute to high homocysteine, tell how to detect it if it's too high, and explain how to dramatically lower it.

Physical activity exerts an important influence on the endocrine system, modulating synthesis and secretion of several hormones. Almost every organ and system in the body is affected by physical activity and exercise, mainly through the endocrine and neuroendocrine system. Mode, intensity, and duration of the exercise bout, age, gender and fitness level of the individual as well as environmental and psychological factors may affect the endocrine response to physical activity. On the other hand, several hormones are able to influence physical performance and body composition. Thus, a bi-univocal interrelationship between exercise and hormones exists. In this book new developments on metabolic and endocrine response to exercise are revised and introduce the "hot topic" of hormonal doping in sports. In the past decades, hormone abuse has become a widespread habit among professional and - most of all and more frequently - recreational athletes. A substantial part of this volume is devoted to the effects of exogenous hormones on performance. Anabolic steroids, growth hormone and erythropoietin properties, use and misuse in sports are widely described. Specific methods to detect hormone abuse are presented and discussed. The contributors to this volume are well-known experts and dedicated researchers in the fields of sports medicine and endocrinology, endocrine physiology, pharmacology, and doping detection. The purpose of this volume is to provide all professionals involved in sports medicine and endocrinology a state-of-the-art overview of the complex interactions between physical activity and the endocrine system and to focus on hormone abuse in sports at competitive and recreational level highlighting its negative consequences for long-term health.

Principles of Heart Valve Engineering is the first comprehensive resource for heart valve engineering that covers a wide range of topics, including biology, epidemiology, imaging and cardiovascular medicine. It focuses on valves, therapies, and how to develop safer and more durable artificial valves. The book is suitable for an interdisciplinary audience, with contributions from bioengineers and cardiologists that includes coverage of valvular and potential future developments. This book provides an opportunity for bioengineers to study all topics relating to heart valve engineering in a single book as written by subject matter experts.

This book provides an update of recent advances in the basic and clinical applications of cell-based therapies for myocardial repair and regeneration in ischemic heart disease (IHD) and heart failure (HF). The first sections of the book illuminate basic aspects of stem cells such as definitions, isolation criteria and characterization of embryonic and adult stem cells, as well as pluripotent stem cells and tissue specific progenitor and stem cells. In the following section, the text examines the role of critical regulators of stem cell differentiation in myocardial regeneration, that include circadian rhythyms, microRNAs, epigenetics, microvescicles, and exosomes. The text concludes with a review of the use of stem/progenitor cells in cardiac regeneration and discuss current controversies, unresolved issues, challenges, and future directions. Stem Cells and Cardiac Regeneration is addressed to a wide audience consisting of cardiologists, clinicians, and research scientists, who will learn new concepts in cardiovascular regeneration and repair with special focus on molecular mechanisms and therapeutic potential for cardiovascular regeneration.

ESSENTIAL MANUAL OF 24-HOUR BLOOD PRESSURE MANAGEMENT Hypertension is one of the greatest threats to human health. The World Health Organization (WHO) estimates that 1.13 billion people worldwide have hypertension. In 2017, new guidelines for managing hypertension were published by the American Hypertension Association (AHA), guidelines which lowered the diagnosis thresholds of hypertension, and thereby increased the prevalence of hypertension. As such, hypertension is now recognized as a more serious and widespread a condition than ever before. In this new edition of the Essential Manual of 24-Hour Blood Pressure Management, the author emphasizes that lowering the blood pressure (BP) and restoring the BP profile with adequate circadian rhythm is essential for a long life without cardiovascular events. The author also introduces updated evidence for managing hypertension throughout 24-hour periods, from morning to nocturnal hypertension. The Essential Manual of 24-Hour Blood Pressure Management, Second Edition, will be an essential companion for doctors who wish to provide evidence-based medicine and be familiar with the most cutting edge technology on monitoring BP. Medical researchers and students will also value the author's many insights, drawn from his distinguished career.

Atrial Fibrillation from an Engineering Perspective provides an up-to-date overview of techniques developed for acquisition, modeling, and analysis of noninvasive, bioelectrical signals reflecting this common arrhythmia. Special emphasis is put on emerging technologies for monitoring of atrial fibrillation in connection with ischemic stroke, interventional ablation procedures, and pharmacological treatment, applications which all depend on the availability of techniques for detecting and characterizing episodes of paroxysmal atrial fibrillation. Detectors exploring both rhythm and morphology are described, as well as detectors confined to rhythm and better suited for low power implementation. A wide variety of approaches to modeling and characterization of atrial activity are described, emanating from a statistical and deterministic starting points. This book is suitable for graduate students, researchers, and engineers who want a comprehensive treatise of atrial fibrillation from an engineering perspective. It may be used for self-study, as a supplement to courses in signal processing, or as a modern monograph by researchers in the field of atrial fibrillation.

Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.

This book introduces the latest research in molecular, cellular, and tissue engineering of the vascular system. Topics covered include the roles of endothelial surface glycocalyx as a mechano-sensor and transducer for blood flow, a barrier to water and solute transport across the vascular wall and to the interaction between circulating cells and the vessel wall, the roles of nuclear envelope proteins and nuclear lamina in regulating vascular functions under blood flow-induced forces, and the roles of smooth muscle cells and extracellular components in arterial vasoconstriction. Other topics covered include non-surgical vascular interventions for coronary artery diseases, genesis and mechanisms of atherosclerotic plaque microcalcifications and human abdominal aortic aneurysms, experiments and modelling for red blood cell and tumor cell movement in microcirculation, transport across the blood-brain barrier and its role in Alzheimer's disease, mathematical models for cell survival after hyperthermia, application of hypothermia in enhancing treatment for brain and spinal cord injuries, and damage of eardrums due to blast waves. This is an ideal book for biomedical engineers and researchers, medical researchers, and students in biomedical engineering and medical sciences.

This book on cardiac extracellular matrix (ECM) features three sections, Fundamental Science, Pre-Clinical and Translational Science, and Clinical Applications. In the Fundamental Science section, we will cover the spectrum of basic ECM science from ECM's role in development, biomechanical properties, cardiac ECM influence of cardiomyocyte biology, pathophysiology of ECM in heart disease, and ECM in tissue engineering. Section two, Preclinical and Translational Science, will discuss cardiac ECM technologies in the clinical pipeline including approaches to ECM as a therapeutic, animal models of cardiac research, tracking and imaging methods of cardiac ECM, and cGMP manufacturing and regulatory considerations for ECM based therapeutics. Finally, the third section, Clinical Applications, will highlight the clinical experience around cardiac ECM including therapeutic strategies targeting scar tissue in the heart, Clinical trial design and regulatory considerations, current human clinical trials in cardiovascular medicine and the role of pharmaceutical and biotech companies in the commercialization of ECM technologies for cardiovascular indications. This book provides a comprehensive review for basic and translational researchers as well as clinical practitioners and those involved in commercialization, regulatory and entrepreneurial activities.

Heart disease kills causes almost one in four of all deaths in the United States, and is the leading cause of death in both men and women. In the UK, the figures are similar. But there are things we can do to look after our hearts, and to ensure that we are not one of those who die prematurely. Looking after ourselves not only makes us feel better, it means we live longer. In this comprehensive introduction, GP Simon Atkins looks at the heart, how it works, and what the common malfunctions are, covering the common symptoms, causes, specific investigations, treatment and outlook. This book will help you give your heart the best chance of carrying on beating for many years to come.

Using a practical, case-based format, this superbly illustrated atlas by Dr. Paul Sorajja is a comprehensive collection of more than 130 professional experiences in treating structural heart disease. Organized by pathology, each case presents key clinical points for practitioners at all levels, from beginner to expert. Cases are provided by interventionalists and surgeons with extensive hands-on experience, and edited by experts in the field Includes more than 130 cases covering the full range of structural procedures formitral valve disease, aortic valve disease, prosthetic valve disease, congenital heart disease, hypertrophic cardiomyopathy, and tricuspid disease. Features more than 500 detailed instructional images for quick visual comprehension of essential aspects of each case. Each case includes clinical information, diagnostic images, bulleted learning points, and explanations and rationales for every step of the procedure. Covers catheter-based therapy for structural heart disease - an increasingly important and rapidly growing therapy for valvular heart disease. Provides operator pitfalls and errors to help optimize success with each procedure. Allows practitioners at all levels of experience to explore, gain insight, and learn important keys for success. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

For courses in reading electrocardiograms This conversational text teaches EKG from basic to advanced concepts Unlike books that encourage rote memorization, the conversationally-written EKG Plain and Simple puts the student at the patient's bedside. This popular text focuses not just on identifying rhythms or EKGs, but also on what can be done for the patient. Assuming no prior knowledge, the text covers basic to advanced EKG concepts. Part I progresses seamlessly from basic cardiac A&P through waves and complexes, lead morphology, and rhythms. Part II covers 12-lead interpretation, axis, hypertrophy, myocardial infarction, and more. The author provides many clinical scenarios, anecdotes, and critical-thinking exercises, plus over 500 practice rhythm strips and 12-lead EKGs. The Fourth Edition has been updated to include improved opening scenarios, streamlined explanations, new tables, and more photos, art, and visual aids. Also available with MyHealthProfessionsLab Now available packaged with the Fourth Edition of EKG Plain and Simple, MyHealthProfessionsLab is an online homework, tutorial, and assessment program designed to work with this text to engage students and improve results. No matter their learning style, students will gain a solid foundation in EKG interpretation through pre-built homework assignments, interactive case studies with assessments, animations, videos, and more! Practice CCT and CET exams provide a true-to-life experience that prepares students for their certification exams. Within MyHealthProfessionsLab's structured environment, students gain knowledge that will carry through to their professional careers. Note: You are purchasing a standalone product; MyHealthProfessionsLab does not come packaged with this content. Students, if interested in purchasing this title with MyHealthProfessionsLab , ask your instructor for the correct package ISBN and Course ID. Instructors, contact your Pearson representative for more information. If you would like to purchase both the physical text and MyHealthProfessionsLab, search for: 9780134627243 / 0134627245 EKG Plain and Simple Plus NEW MyHealthProfessionsLab with Pearson eText--Access Card Package, 4/e contains: 9780134525051 / 0134525051 EKG Plain and Simple 9780134525495/ 0134525493 MyHealthProfessionsLab with Pearson eText -- Access Card -- for EKG Plain and Simple

For all courses in basic or introductory cardiography Focused coverage and realistic hands-on practice help students master basic arrhythmias Basic Arrhythmias, Eighth Edition, gives beginning students a strong basic understanding of the common, uncomplicated rhythms that are a foundation for further learning and success in electrocardiography. Concepts are presented in a flexible, progressive approach to allow for self-paced or classroom learning. Chapters cover basic electrophysiology, waves and measurements, rhythm analysis, and the five major groups of arrhythmias. Basic Arrhythmias includes appendices on Clinical Implications, Cardiac Anatomy and Physiology, 12-Lead Electrocardiography, Basic 12-Lead Interpretation, and Pathophysiology of Arrhythmias. Practice EKG rhythm strips are included in most chapters to give students extensive, realistic hands-on practice-the single most important element in developing arrhythmia interpretation skills. Also available with MyBRADYLab (R) MyBRADYLab is an online homework, tutorial, and assessment program that gives you the power to reach students on their terms-and to teach however you like. Encourage students to immerse themselves in the Pearson eText on their own time and use your classroom sessions to workshop key concepts. Or, enhance your lectures with videos and other engaging content that brings course material to life. Fostering engagement both within and outside the classroom, MyBRADYLab helps students better prepare for class, quizzes, and exams-resulting in improved performance in the course. Students, if interested in purchasing this title with MyBRADYLab, ask your instructor for the correct package ISBN and Course ID. Instructors, contact your Pearson representative for more information.

This timely book is a road map for defining the care of acute heart failure patients in the short stay or observation unit setting. Produced in collaboration with the Society of Chest Pain Centers, this book provides an understanding of the diverse medical needs and solutions, administrative processes, and regulatory issues necessary for successful management. In an environment of increasing financial consciousness, medical practice is changing drastically. Short stay care is premier among the new specialties that cater to the complex balance of optimizing patient outcomes while minimizing fiscal burdens. The observation unit has proven to be an excellent arena for the care of acute heart failure, replete with opportunities to improve both medical management and quality metrics. Unique to the field, Short Stay Management of Acute Heart Failure, Second Edition is the only book of its kind, providing the medical, regulatory, and economic tools necessary to create and implement successful short stay management protocols and units for the care of the heart failure patient. It is an essential guide for health care professionals and for hospitals and institutions wishing to be recognized as quality heart failure centers as accredited by the Society of Chest Pain Centers.

This text covers the basic principles of mitochondrial dynamics in cardiovascular medicine, with particular emphasis on their functional roles in physiology and disease. The book will include articles pertaining to mitochondrial fitness on a global basis, providing therefore an update on the progress made in several aspects in the field. Thus, it will assist scientists and clinicians alike in furthering basic and translational research. Organized in sections focusing on: basic science, mitochondrial dysfunction in cardiac disorders, in vascular disorders, in metabolic disorders, in kidney disease, therapeutic challenges and options, this essential volume fills imperative gaps in understanding and potentially treating several cardiovascular disorders.

Cardiovascular immunology is a newly emerging research area, investigating the crosstalk between the cardiovascular and the immune system. This crosstalk is evident through (1) crucial immunological capacities and functions of cardiovascular cell types, including cardiomyocytes, fibroblasts, endothelial cells, pericytes and cardiac resident macrophages, (2) the impact of aberrant immune function on the development of cardiovascular disease such as atherosclerosis, direct and indirect immune-mediated heart disease and vasculitis, and (3) the crucial role of the immune system in cardiac repair and regeneration. The Immunology of Cardiovascular Homeostasis and Pathology covers all these aspects of cardiovascular immunology, starting with homeostatic immunological functions of traditional cardiovascular cell types, and moving then to the role of the immune system in cardiovascular pathology and to recent research into targeting the immune system to boost cardiac healing and regeneration.