It is a distressing truism that the human race during the last millennium has caused the exponential loss of plant genetic diversity throughout the world. This has had direct and negative economic, political and social consequences for the human race, which at the same time has failed to exploit fully the positive benefits that might result from conserving and exploiting the world's plant genetic resources. However, a strong movement to halt this loss of plant diversity and enhance its utilisation for the benefit of all humanity has been underway since the 1960's (Frankel and Bennett, 1970; Frankel and Hawkes, 1975). This initiative was taken up by the Convention on Biological Diversity (CBD, 1992) that not only expounds the need to conserve biological diversity but links conservation to exploitation and development for the benefit of all. Article 8 of the Convention clearly states the need to develop more effective and efficient guidelines to conserve biological diversity, while Article 9, along with the FAO International Undertaking on Plant Genetic Resources, promotes the adoption of a complementary approach to conservation that incorporates both ex situ and in situ techniques.

Sixteen volumes and one supplement have now appeared in the series known as Evolutionary Biology. The editors continue to seek critical re views, original papers, and commentaries on controversial topics. It is our aim to publish papers primarily of greater length and depth than those normally published by society journals and quarterlies. The editors make every attempt to solicit manuscripts on an international scale and to see that every facet of evolutionary biology-classical or modern-is cov ered. Manuscripts should be sent to anyone of the following: Max K. Hecht, Department of Biology, Queens College of the City University of New York, Flushing, New York 11367; Bruce Wallace, Department of Biology, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061; Ghillean T. Prance, New York Botanical Garden, Bronx, New York 10458. The Editors vii Contents 1. Darwinian Selection of Self-Replicating RNA Molecules 1 Christ( r K. Biehricher Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Replication of Virus RNA in Vitro. . . . . . . . . . . . . . . . . . . . . . . . 2 Extracellular Darwinian Experiments. . . . . . . . . . . . . . . . . . . . . . 5 Characterization of the QI3 Replicase. . . . . . . . . . . . . . . . . . . . . . 9 Nonviral RNA Templates of QI3 Replicase. . . . . . . . . . . . . . . . . . II The Mechanism of RNA Replication . . . . . . . . . . . . . . . . . . . . . . 14 Initiation of Replication and Template Specificity . . . . . . . . . . . 14 Mechanism of Replica Chain Elongation. . . . . . . . . . . . . . . . . . 17 Termination of Replication. . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 Replication of RNA Variants . . . . . . . . . . . . . . . . . . . . . . . . . . 21 The Quasispecies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23 De NOl'O Synthesis of Self-Replicating RNA. . . . . . . . . . . . . . . . . 27 The Mechanism of Selection . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 Selection in the Exponential Growth Phase. . . . . . . . . . . . . . . . 32 Selection in the Linear Growth Phase. . . . . . . . . . . . . . . . . . . . 35 Conclusions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 Appendix I. Replication. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42 Appendix II. The Quasispecies. . . . . . . . . . . . . . . . . . . . . . . . . . . 43 Appendix III. Selection under Various Conditions . . . . . . . . . . . . 44 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ."

Chaos in Real Data studies the range of data analytic techniques available to study nonlinear population dynamics for ecological time series. Several case studies are studied using typically short and noisy population data from field and laboratory. A range of modern approaches, such as response surface methodology and mechanistic mathematical modelling, are applied to several case studies. Experts honestly appraise how well these methods have performed on their data. The accessible style of the book ensures its readability for non-quantitative biologists. The data remain available, as benchmarks for future study, on the worldwide web.

Living material contains about twenty different sorts of atom combined into a set of relatively simple molecules. Astrobiologists tend to believe that abiotic mater ial will give rise to life in any place where these molecules exist in appreciable abundances and where physical conditions approximate to those occurring here on Earth. We think this popular view is wrong, for it is not the existence of the building blocks of life that is crucial but the exceedingly complicated structures in which they are arranged in living forms. The probability of arriving at biologically significant arrangements is so very small that only by calling on the resources of the whole universe does there seem to be any possibility of life originating, a conclusion that requires life on the Earth to be a minute component of a universal system. Some think that the hugely improbable transition from non-living to living mat ter can be achieved by dividing the transition into many small steps, calling on a so-called 'evolutionary' process to bridge the small steps one by one. This claim turns on semantic arguments which seek to replace the probability for the whole chain by the sum of the individual probabilities of the many steps, instead of by their product. This is an error well known to those bookies who are accustomed to taking bets on the stacking of horse races. But we did not begin our investigation from this point of view.

Polyploidy - whole-genome duplication (WGD) - is a fundamental driver of biodiversity with significant consequences for genome structure, organization, and evolution. Once considered a speciation process common only in plants, polyploidy is now recognized to have played a major role in the structure, gene content, and evolution of most eukaryotic genomes. In fact, the diversity of eukaryotes seems closely tied to multiple WGDs. Polyploidy generates new genomic interactions - initially resulting in "genomic and transcriptomic shock" - that must be resolved in a new polyploid lineage. This process essentially acts as a "reset" button, resulting in genomic changes that may ultimately promote adaptive speciation. This book brings together for the first time the conceptual and theoretical underpinnings of polyploid genome evolution with syntheses of the patterns and processes of genome evolution in diverse polyploid groups. Because polyploidy is most common and best studied in plants, the book emphasizes plant models, but recent studies of vertebrates and fungi are providing fresh perspectives on factors that allow polyploid speciation and shape polyploid genomes. The emerging paradigm is that polyploidy - through alterations in genome structure and gene regulation - generates genetic and phenotypic novelty that manifests itself at the chromosomal, physiological, and organismal levels, with long-term ecological and evolutionary consequences.

Phylogenetic analysis and morphometrics have been developed by biologists into rigorous analytic tools for testing hypotheses about the relationships between groups of species. This book applies these tools to paleontological data. The fossil record is our one true chronicle of the history of life, preserving a set of macroevolutionary patterns; thus various hypotheses about evolutionary processes can be tested in the fossil record using phylogentic analysis and morphometrics. The first book of its type, Fossils, Phylogeny, and Form will be useful in evolutionary biology, paleontology, systematics, evolutionary development, theoretical biology, biogeography, and zoology. It will also provide a practical, researcher-friendly gateway into computer-based phylogenetics and morphometrics.

This book brings together most of the information available concerning two species that diverged 2-3 million years ago. The objective was to try to understand why two sibling species so similar in several characteristics can be so different in others. To this end, it was crucial to confront all data from their ecology and biogeography with their behavior and DNA polymorphism. Drosophila melanogaster and Drosophila simulans are among the two sibling species for which a large set of data is available. In this book, ecologists, physiologists, geneticists, behaviorists share their data on the two sibling species, and several scenarios of evolution are put forward to explain their similarities and divergences. This is the first collection of essays of its kind. It is not the final point of the analyses of these two species since several areas remain obscure. However, the recent publication of the complete genome of D. melanogaster opens new fields for research. This will probably help us explain why D. melanogaster and D. simulans are sibling species but false friends.

Recent work in quantitative biology has shown theoretically why Fisher's Fundamental Theorem of Natural Selection does not preclude genetic influences on fertility, sexuality, and related processes. Genetic Influences on Human Fertility and Sexuality takes the next step, and presents a number of successful empirical searches for such genetic influence on a broad range of processes, such as puberty, marriage, sexual behavior, and twinning. Employing a broad range of methodological approaches, including molecular and behavioral genetics, this book weaves a new theoretical framework that shows how genes can help relate fertility planning to fertility outcome, and how puberty, sexuality, marriage, and reproduction can be conceptually linked through the genes that contribute to individual differences in the human process.

Plant molecular biology has produced an ever-increasing flood of data about genes and genomes. Evolutionary biology and systematics provides the context for synthesizing this information. This book brings together contributions from evolutionary biologists, systematists, developmental geneticists, biochemists, and others working on diverse aspects of plant biology whose work touches to varying degrees on plant molecular evolution. The book is organized in three parts, the first of which introduces broad topics in evolutionary biology and summarizes advances in plant molecular phylogenetics, with emphasis on model plant systems. The second segment presents a series of case studies of gene family evolution, while the third gives overviews of the evolution of important plant processes such as disease resistance, nodulation, hybridization, transposable elements and genome evolution, and polyploidy.

One of the major themes of human population genetics is assaying genetic variation in human populations. The ultimate goal of this objective is to understand the extent of genetic diversity and the use of this knowledge to reconstruct our evolutionary history. The discipline had undergone a revolutionary transition with the advent of molecular techniques in the 1980s. With this shift, statistical methods have also been developed to perceive the biological and molecular basis of human genetic variation. Using the new perspectives gained during the above transition, this volume describes the applications of molecular markers spanning the autosomal, Y-chromosomal and mitochondrial genome in the analysis of human diversity in contemporary populations. This is the first reference book of its kind to bring together data from these diverse sets of markers for understanding evolutionary histories and relationships of modern humans in a single volume.

Comparative Vertebrate Reproduction is the only comprehensive textbook covering major topics in the reproductive biology of vertebrates, from sexuality and gametogenesis to reproductive ecology and life history tactics. The work draws heavily on recent reviews and papers while placing topics in a historical context and conceptual framework. In addition, the author provides detailed comparative surveys of each of the major topics discussed. Comparative Vertebrate Reproduction has been written as a textbook for upper-level undergraduate and graduate-level students in biology, zoology, physiology, animal science, and veterinary medicine. The work also serves as an excellent reference for researchers in medical and veterinary schools working in reproductive medicine.

I was asked to introduce this volume by examining "why a knowledge of ecosys tem functioning can contribute to understanding species activities, dynamics, and assemblages." I have found it surprisingly difficult to address this topic. On the one hand, the answer is very simple and general: because all species live in ecosystems, they are part of and dependent on ecosystem processes. It is impossible to understand the abundance and distribution of populations and the species diversity and composition of communities without a knowledge of their abiotic and biotic environments and of the fluxes of energy and mat ter through the ecosystems of which they are a part. But everyone knows this. It is what ecology is all about (e.g., Likens, 1992). It is why the discipline has retained its integrity and thrived, despite a sometimes distressing degree of bickering and chauvinism among its various subdisciplines: physiological, be havioral, population, community, and ecosystem ecology."

4.1.1 Demographic significance Confined populations grow more rapidly than populations from which dispersal is permitted (Lidicker, 1975; Krebs, 1979; Tamarin et at., 1984), and demography in island populations where dispersal is restricted differs greatly from nearby mainland populations (Lidicker, 1973; Tamarin, 1977, 1978; Gliwicz, 1980), clearly demonstrating the demographic signi ficance of dispersal. The prevalence of dispersal in rapidly expanding populations is held to be the best evidence for presaturation dispersal. Because dispersal reduces the growth rate of source populations, it is generally believed that emigration is not balanced by immigration, and that mortality of emigrants occurs as a result of movement into a 'sink' of unfavourable habitat. If such dispersal is age- or sex-biased, the demo graphy of the population is markedly affected, as a consequence of differ ences in mortality in the dispersive sex or age class. Habitat heterogeneity consequently underlies this interpretation of dispersal and its demographic consequences, although the spatial variability of environments is rarely assessed in dispersal studies."

This volume brings together the disciplines of plant and animal genome research, and serves as an opportunity for scientists from both fields to compare results, problems and prospects.

"De la vaporisation et de la centralisation du Moi. Tout est la. " Charles Baudelaire (journal entry) This anthology is my visit to Oz. On sabbatical in 1988, I chose to reeducate myself in general biology, first broadening my erudition as an immunologist, and then extending that horizon into evolutionary biology and embryology. I was particularly attracted to reflections on the nature of the self as an organ ismic concept. I went in search of reorientation as a confused physician scientist, and came back with this book. Baum's Wizard of Oz presented opportunities for growth, and herein lies the purpose of this volume: in providing updated statements concerning the nature of the organism from both scientific and metaphysical perspectives, we might ponder the philo sophical basis of our research in the hope of gaining insight into our endeavor, not to mention the possibility of its enrichment; it is this contem plative view of our research which offers a unique dimension to this anthology. To that end, the project follows my idiosyncratic prejudices. The anthology derives in large measure from the symposium, "Organism and the Origin of Self' held at Boston University, April 3-4, 1990, under the auspices of the Boston University Center for the Philosophy and History of Science, with generous support of Robert Cohen and Jon Westling, and the organizational skills of Deborah Wilkes. The Symposium presented three ver sions of the Self from the vantages of embryology, evolution and medicine."

From the Preface: The chapters of this book contain contributions from an international group of specialists. They address some important themes in both modern and ancient reef systems. Some chapters contain 'snapshots' of reefs of particular intervals, while others touch on relevant themes of both modern and ancient reefs - themes that weave their way through reefs of all ages. This book opens and sets the stage with an introduction to both modern and ancient reefs and reef ecosystems. This chapter is also intended as a basic introduction for students, general geologists, and professionals or others who may be unfamiliar with reefs and reef ecosystems. The chapter addresses the living coral reef ecosystem, stressing among other relevant factors, the importance of ecological and physical interactions between the organisms and their environment. The chapter also addresses mass extinction and provides a general overview of the history of reefs.

I have long been awe-struck by authors' claims that their books had been in the making for 5, or 10, or even 15 years. I now have a better appreciation ofthe work involved in bringing a book to press. The seeds of this project have had a long germination. The impetus for this book began more than 10 years ago when I was a graduate student in clinical psychology. Having an interest in human sexuality-and in theories on the forms of sexual attraction specifically-I was perplexed by various perspectives on this subject. Disciplines of thought that I encountered medicine, evolutionary biology, developmental psychology, gay/lesbian theory, social constructionism, anthropology, Marxism, Christianity, and others-perceived the issue so differently, so strongly, with almost no overlap. I was fascinated that the question ofhow and why one is attracted to either one or both sexes could elicit such conviction and divergent points of view. There seemed to be no easy way to resolve these differences. Still, what frustrated me most in my readings were several conceptual problems among the two prominent proponents of contemporary sexuality theory scientists and social constructionists. One ofmy first frustrations with biomedical and social scientists who write about sexuality was that they often define sexual attraction in strict behavioral terms, as completed observable sexual acts--observable in the sense that such acts or their consequences are seen by others.

Many mites possess extremely intricate life styles in close association with plant and animal hosts. Their polymorphism has made classification a challenge, and their ability to reproduce both sexually and asexually has made efforts to control their populations difficult. This, however, has given rise to theories to explain the origin and function of sexual reproduction in general. In numbers of species and geographic distribution, mites may even surpass the insects. In soils, they are a major component in the system for cycling nutrients. Unlike insects, they have invaded the marine environment. These and a number of other topics are explored in Mites. Because of their extremely small size, mites have been ignored during the development of major evolutionary and ecological theories. Yet mites routinely violate fundamental concepts such as heterochrony, sexual selection, the evolution of sex ratio, and ontogeny. Recent research methodologies have made it practical for the first time to perform experimental work with mites, and since they offer short generation times and rapid research results, they are excellent model systems. Mites announces these results and should appeal to professionals in entomology, acarology, ecology, population genetics, and evolutionary biology.

After volume 33, this book series was replaced by the journal "Evolutionary Biology." Please visit www.springer.com/11692 for further information. The nature of science is to work on the boundaries between the known and the unknown. These boundaries shift as new methods are developed and as new concepts are elaborated (e.g., the theory of the gene, or more recently, the coalescence framework in population genetics). These tools allow us to address questions that were previously outside the realm of science, and, as a consequence, the boundary between the knowable and unknowable has shifted. A study of limits should reveal and clarify the boundaries and make sharper the set of questions. This book examines and analyzes these new limits as they are applied to evolutionary biology and population genetics. It does this by framing the analysis within four major classes of problems - establishing the fact of evolution; understanding the evolutionary pathways that led to today's biological world; mechanisms of evolutionary change (e.g., models of social behavior, sexual selection, macro evolution); and, finally, prediction.

Biogeography relates the evolution of the Earth's biota to major episodes in the Earth's history such as climatic changes and plate tectonic events. Furthermore, biogeographic patterns have played a prominent role in the development of the theory of evolution. Thus biogeography has the potential to make important contributions to the field of geobiology. Paleobiogeography emphasizes how analytical techniques from phylogenetic biogeography can be applied to the study of patterns in the fossil record. In doing this, it considers the strengths and weaknesses of paleobiogeographic data, the effects of plate tectonic processes (specifically continental rifting and collision) and changes in relative sea levels in terms of how they influence the evolution and distribution of organisms.

From the Foreword: "Predator-prey interactions are among the most significant of all organism-organism interactions....It will only be by compiling and evaluating data on predator-prey relations as they are recorded in the fossil record that we can hope to tease apart their role in the tangled web of evolutionary interaction over time. This volume, compiled by a group of expert specialists on the evidence of predator-prey interactions in the fossil record, is a pioneering effort to collate the information now accumulating in this important field. It will be a standard reference on which future study of one of the central dynamics of ecology as seen in the fossil record will be built." (Richard K. Bambach, Professor Emeritus, Virginia Tech, Associate of the Botanical Museum, Harvard University)

Initially, this work was designed to document and study the diversification of modern mammalian groups and was quite successful and satisfying. However, as field and laboratory work continued, there began to develop a suspicion that not all of the Eocene story was being told. It became apparent that most fossil samples, especially those from the American West, were derived from similar preservational circumstances and similar depositional settings. A program was initiated to look for other potential sources of fossil samples, either from non-traditional lithologies or from geographic areas that were not typically sampled. As this program of research grew it began to demonstrate that different lithologies and different geographic areas told different stories from those that had been developed based on more typical faunal assemblages. This book is conceived as an introduction to non-traditional Eocene fossils samples, and as a place to document and discuss features of these fossil assemblages that are rare or that come from rarely represented habitats.

Based on the author's more than 40 years experience, Bacterial Growth and Form examines such important questions as what bacteria were, what they are, and what they do. Particular emphasis is placed on the ability of bacteria to establish their shapes as they grow and divide. By developing an understanding of the properties of these simple and early life forms, especially at the levels of physics and mathematics, the book provides insight into the mechanism used by bacteria to subvert physical forces to their own ends. A major consideration of this work is that prokaryotes do many of the same things that eukaryotes do, but with simpler equipment employed in an extremely sophisticated way. The book illustrates this point by closely examining the basic mechanismof hydrostatic or turgor pressure: how it functions for many of the mechanical purposes in the prokaryote, how it leads to mechanisms for resisting turgor pressure, and how it ultimately led to the development of exoskeletons and endoskeletons, and to the refinement of bacteria. Bacterial Growth and Form brings together biochemical, biophysical, and physiological principles in an authoritative, single-source volume. It provides researchers, and students in biophysics and microbiology with an indispensible reference and a new perspective into the biology of life.

This series presents studies that have used the paradigm of landscape ecology. Other approaches, both to landscape and landscape ecology are common, but in the last decade landscape ecology has become distinct from its predecessors and its contemporaries. Landscape ecology addresses the relationships among spatial patterns, temporal patterns and ecological processes. The effect of spatial configurations on ecological processes is fundamental. When human activity is an important variable affecting those relationships, landscape ecology includes it. Spatial and temporal scales are as large as needed for comprehension of system processes and the mosaic included may be very heterogeneous. Intellec tual utility and applicability of results are valued equally. The Inter national Association for Landscape Ecology sponsors this series of studies in order to introduce and disseminate some of the new knowledge that is being produced by this exciting new environmental science. Gray Merriam Ottawa, Canada Foreword This is a book about real nature, or as close to real as we know - a nature of heterogeneous landscapes, wild and humanized, fine-grained and coarse-grained, wet and dry, hilly and flat, temperate and not so temper ate. Real nature is never uniform. At whatever spatial scale we examine nature, we encounter patchiness. If we were to look down from high above at a landscape of millions of hectares, using a zoom lens to move in and out from broad overview to detailed inspection of a square meter we would see that patterns visible at different scales overlay one another."