Biotechnology and Competitive Advantage investigates the development of biotechnology in Europe and the United States. It examines why Europe has fallen behind in applying biotechnology, when its scientific capabilities are largely comparable to those in the US. In addition it sheds new light on the wider context of the theory of growth of new technologies. This innovative book brings together a wide range of material concerning socio-economic aspects of the development of biotechnology in Europe and the US. Issues discussed include: * European policy for biotechnology, in individual countries and at the European Union level * risk regulation and the ways in which industry, regulators and non-government organizations manage risk regulation and the perception of risk * the formation and roles of biotechnology firms in Europe and the US and their relative capabilities * gene therapy development in Europe and the US * the impact on Europe of overseas biotechnology research by European multinationals. This book argues in favour of developing an integrated research and development system which will strengthen the research and development capabilities of all the actors involved. This book will be of great interest to science policymakers; businesses and academics studying the development of biotechnology and students of economics and business studies throughout Europe and the US.

This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.

This book addresses the important clinical problem of accurately diagnosing osteoporosis, and analyzes how Bone Turnover Markers (BTMs) can improve osteoporosis detection. In her research, the author integrated microfluidic technology with electrochemical sensing to embody a reaction/detection chamber to measure serum levels of different biomarkers, creating a microfluidic proteomic platform that can easily be translated into a biomarker diagnostic. The Osteokit System, a result of the integration of electrochemical system and microfluidic chips, is a unique design that offers the potential for greater sensitivity. The implementation, feasibility, and specificity of the Osteokit platform is demonstrated in this book, which is appropriate for researchers working on bone biology and mechanics, as well as clinicians.

Contents - 1. SOLIDS-STORAGE AND HANDLING - General - Conveyors - Drying - 2. LIQUIDS-STORAGE AND HANDLING - Tanks - Pumps - Mechanical Seals - 3. GASES-STORAGE AND HANDLING - General - Handling Air - Types of Apparatus - 4. PIPE, FITTINGS, VALVES - Pipe Types- Valve Types - 5. MIXING OF MATERIALS - Blending of Solids - Mixing of Fluids - Operating Notes - 6. HEATING AND COOLING - General - Heat Exchangers - Suggestions for Operation - 7. SEPARATION OF MATERIALS - Solids from Solids - Solids from Liquids - Liquids from Liquids - Gases from Gases - 8. UTILITIES - Heating Systems - Cooling Systems - Refrigeration - Process Water - Electrical Systems - Air Systems - 9. INSTRUMENTS FOR PRESSURE - General - Indicators - Transmitters - Regulators - 10. INSTRUMENTS FOR TEMPERATURE - Primary Elements - Transmitters - Regulators - 11. INSTRUMENTS FOR FLOW AND LIQUID LEVEL - Indicators - Flow Transmitters - Liquid Level Indicators and Transmitters - 12. INSTRUMENTS FOR CONTROL - Recorders and Integrators - Controllers - Operating Pointers - Control Valves - Miscellaneous -

Contents: Gerard Jaouen, Nils Metzler-Nolte : Introduction ; Stephane GIBAUD and Gerard JAOUEN: Arsenic - based drugs: from Fowler's solution to modern anticancer chemotherapy; Ana M. Pizarro, Abraha Habtemariam and Peter J. Sadler : Activation Mechanisms for Organometallic Anticancer Complexes; Angela Casini, Christian G. Hartinger, Alexey A. Nazarov, Paul J. Dyson : Organometallic antitumour agents with alternative modes of action; Elizabeth A. Hillard, Anne Vessieres, Gerard Jaouen : Ferrocene functionalized endocrine modulators for the treatment of cancer; Megan Hogan and Matthias Tacke : Titanocenes - Cytotoxic and Anti-Angiogenic Chemotherapy Against Advanced Renal-Cell Cancer; Seann P. Mulcahy and Eric Meggers : Organometallics as Structural Scaffolds for Enzyme Inhibitor Design; Christophe Biot and Daniel Dive : Bioorganometallic Chemistry and Malaria; Nils Metzler-Nolte : Biomedical applications of organometal-peptide conjugates; Roger Alberto : Organometallic Radiopharmaceuticals; Brian E. Mann : Carbon Monoxide - an essential signaling molecule.

This thesis describes an in-depth study of an indolizine-based fluorophore, from understanding of its structure-photophysical property relationship to its application as a useful biological reporter. Organic fluorophores have been extensively used in the field of molecular biology owing to their excellent photophysical property, suitable cell permeability, and synthetic flexibility. Understanding of the structure-photophysical property relationship of a given fluorophore often paves the road to the development of valuable molecular probes to visualize and transcribe biological networks. In this thesis, respective chapters deal with molecular design, organic synthesis, structure-property analysis, and quantum-mechanical interpretation of unexplored family of indolizine-based molecules. This systematic exploration has led to rational development of a new microalgae lipid droplet probe, colorful bioorthogonal fluorogenic probes, and a bright mitochondrial probe, working under live cell conditions. Harnessing the optical properties of a given fluorophore has been an important topic for a couple of decades, both in industry and in academia. This thesis provides useful insights for the improvement and development of unique small fluorescent materials, or optical materials.

This book evaluates and discusses the main sustainability challenges encountered in the production of biofuel and bio- products from oil palm biomass. It starts off with the emphasis on oil palm production, oil palm products recovery and oil palm wastes utilization. The simultaneous production of these bio-products for sustainable development is discussed. This is followed by the key factors defining the sustainability of biofuel and bio-product production from oil palm biomass. The environmental issues including ecological, life cycle assessment and environmental impact assessment of oil palm plantation, milling and refining for the production of biofuels and bio-products are presented. Socio- economic and thermodynamic analysis of the production processes are also evaluated using various sustainability assessment tools such as exergy. Lastly, methods of improving biofuel production systems for sustainable development are highlighted.

The withstanding properties of inorganic membranes provide a set of tools for solving many of the problems that the society is facing, from environmental to energy problems and from water quality to more competitive industries. Such a wide variety of issues requires a fundamental approach, together with the precise description of applications provided by those researchers that have been close to the industrial applications. The contents of this book expand the lectures given in a Summer School of the European Membrane Society. They combine an easily accessible description of the technology, suitable for the graduate level, with the most advanced developments and the prospective of future applications. The large variety of membrane types makes almost compulsory to select a specialist for each of them, and this has been the approach selected in this book.
In the case of porous membranes, the advances are related to the synthesis of microporous materials such as silica, carbon and zeolite membranes and hollow fibre membranes. A chapter covers the increasingly relevant hybrid membranes. Attention is also devoted to dense inorganic membranes, experiencing constantly improved properties. The applications of all these membranes are considered throughout the book.
Covers all the inorganic membranes field, by different experts.
It comes from a European Summer School
It includes future directions in the field

Metal Nanoclusters in Catalysis and Materials Science: The Issue of Size Control deals with the synthesis of metal nanoclusters along all known methodologies. Physical and chemical properties of metal nanoclusters relevant to their applications in chemical processing and materials science are covered thoroughly. Special attention is given to the role of metal nanoclusters size and shape in catalytic processes and catalytic applications relevant to industrial chemical processing.
An excellent text for expanding the knowledge on the chemistry and physics of metal nanoclusters. Divided in two parts; Part I deals with general aspects of the matter and Part II has to be considered a useful handbook dealing with the production of metal nanoclusters, especially from their size-control point of view.
* Divided into two parts for ease of reference: general and operational
* Separation of synthetic aspects, physical properties and applications
* Specific attention is given to the task of metal nanoclusters size-control

Introduction to Zeolite Molecular Sieves, 3rd Edition presents a collection of the most important results and ideas in the field of molecular sieve chemistry and technology, the most important experimental techniques related to the research activities in molecular sieves, and identifies new areas of molecular sieve chemistry. Chapters start at a reasonably simple entry level, but also covers the present state-of-the-art in the field.
Topics covered include structure, synthesis, characterization, ion exchange, adsorption, diffusion, separations, and natural zeolites.
* 6 years since the last edtion this book brings together the rapid development within the field of molecular sieve chemistry and applications
* Accessible to newcomers to the field, also containing valuable information for experienced researchers
* 27 chapters written by renowned scientists in their field, including updates on some 2nd edition chapters

Pinch analysis and related techniques are the key to design of inherently energy-efficient plants. This book shows engineers how to understand and optimize energy use in their processes, whether large or small. Energy savings go straight to the bottom line as increased profit, as well as reducing emissions.
This is the key guide to process integration for both experienced and newly qualified engineers, as well as academics and students. It begins with an introduction to the main concepts of pinch analysis, the calculation of energy targets for a given process, the pinch temperature and the golden rules of pinch-based design to meet energy targets.
Supported by valuable downloadable software, the book shows how to extract the stream data necessary for a pinch analysis and describes the targeting process in depth. Other essential details include the design of heat exchanger networks, hot and cold utility systems, CHP (combined heat and power), refrigeration and optimization of system operating conditions. Many tips and techniques for practical application are covered, supported by several detailed case studies and other examples covering a wide range of industries, including buildings and other non-process situations.
* The only dedicated pinch analysis and process integration guide, fully revised and expanded supported by free downloadable energy targeting software
* The perfect guide and reference for chemical process, food and biochemical engineers, plant engineers and professionals concerned with energy optimisation, including building designers
* Covers the practical analysis of both new and existing systems, with ful details of industrial applications and case studies

This volume of Studies in Surface Science and Catalysis contains the Proceedings of the 9th International Symposium on the Scientific Bases for the Preparation of Heterogeneous Catalysts, held on the campus of the "Universit catholique de Louvain" (UCL) in Louvain-la-Neuve, Belgium, on September 10-14, 2006. This series of symposia was initiated in 1975 on a regular 4-year interval basis.
The Symposium covered the following topics: key aspects in catalysts preparation, micro- and mesoporous supports, supported metal catalysts, structured catalysts, tailored zeolites, catalysis by bases, and catalysts for fuel production. These topics served as guidelines for the sessions both in the programs of oral communications (41 contributions including 7 keynote communications - one for each topic) and poster presentations (101 contributions). In addition, the opening invited lecture addressed the question of scaling-up high-throughput experimental approaches.
* Contains a collection of the papers presented at the workshop

The objective of the Springer Handbook of Enzymes is to provide in concise form data on enzymes sufficiently well characterized. Data sheets are arranged in their EC-Number sequence. Each volume comprises one enzyme class, sometimes the enzyme classes have to be divided into several volumes. Considerable progress has been made in enzymology since the publication of the first edition (published as "Enzyme Handbook"): many enzymes are newly classified or reclassified. In the 2nd edition each entry is correlated with references and one or more source organisms. New datafields are created: "application" and "engineering" (for the properties of enzymes where the sequence has been changed). Altogether the amount of data has doubled so that the 2nd edition will consist of 39 volumes plus synonym index. This collection is an indispensable source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences.

The objective of the Springer Handbook of Enzymes is to provide in concise form data on enzymes sufficiently well characterized. Data sheets are arranged in their EC-Number sequence. Each volume comprises one enzyme class, sometimes the enzyme classes have to be divided into several volumes. Considerable progress has been made in enzymology since the publication of the first edition (published as "Enzyme Handbook"): many enzymes are newly classified or reclassified. In the 2nd edition each entry is correlated with references and one or more source organisms. New datafields are created: "application" and "engineering" (for the properties of enzymes where the sequence has been changed). Altogether the amount of data has doubled so that the 2nd edition will consist of 39 volumes plus synonym index. This collection is an indispensable source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences.

The objective of the Springer Handbook of Enzymes is to provide in concise form data on enzymes sufficiently well characterized. Data sheets are arranged in their EC-Number sequence. Each volume comprises one enzyme class, sometimes the enzyme classes have to be divided into several volumes. Considerable progress has been made in enzymology since the publication of the first edition (published as "Enzyme Handbook"): many enzymes are newly classified or reclassified. In the 2nd edition each entry is correlated with references and one or more source organisms. New datafields are created: "application" and "engineering" (for the properties of enzymes where the sequence has been changed). Altogether the amount of data has doubled so that the 2nd edition will consist of 39 volumes plus synonym index. This collection is an indispensable source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences.

There is hardly any technical library in the world in which the volumes of the Chemical Formulary (Volumes 1-34) do not occupy a prominent place. Chemists both experienced and beginner, continually refer to them. Volume 34 counts numerous experts among it's contributors, such as Editor-in-chief H. Bennett. It does not duplicate any of the formulas included in previous volumes, but lists a wide array of modern and salable products from all branches of the chemical industries. An excellent reference for formulation problems.

The objective of the Springer Handbook of Enzymes is to provide in concise form data on enzymes sufficiently well characterized. Data sheets are arranged in their EC-Number sequence. Each volume comprises one enzyme class, sometimes the enzyme classes have to be divided into several volumes. Considerable progress has been made in enzymology since the publication of the first edition (published as "Enzyme Handbook"): many enzymes are newly classified or reclassified. In the 2nd edition each entry is correlated with references and one or more source organisms. New datafields are created: "application" and "engineering" (for the properties of enzymes where the sequence has been changed). Altogether the amount of data has doubled so that the 2nd edition will consist of 39 volumes plus synonym index. This collection is an indispensable source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences.