Smart Solutions for Wastewater: Road-mapping the Transition to Circular Economy, the latest release in the Current Developments in Biotechnology and Bioengineering presents up-to-date information on research and technological developments of resource recovery in wastewater treatment in terms of carbon, nutrients and energy. The book fulfils the gaps and current challenges that hinder the application of resource recovery facilities in wastewater treatment plants, discusses knowledge gaps, provides future research perspectives, and discusses strategies to solve problems from a circular economy perspective. It is an excellent, interdisciplinary and updated overview of technologies in terms of potential yields, pollutants removal, nutrients recovery and energy production.

This volume explores the latest techniques and strategies used to study the field of peptide macrocycles. The chapters in this book ae organized into four parts: macrocycles synthesis, combinational library synthesis and screening, macrocycle characterization, and unique applications. Part One looks at a variety of peptide cyclization methodologies, and Part Two describes methods for the creation of peptide macrocycles libraries and their subsequent screening against biological targets of interest. Part Three discusses the study and characterization of peptide macrocycle-target interactions, and Part Four introduces unique applications for peptide macrocycles, from higher-order structure formation to post-synthetic functional modifications. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Peptide Macrocycles: Methods and Protocols is a valuable resource for both novice and expert researchers looking to learn more about this developing field.

The objective of the Springer Handbook of Enzymes is to provide in concise form data on enzymes sufficiently well characterized. Data sheets are arranged in their EC-Number sequence. Each volume comprises one enzyme class, sometimes the enzyme classes have to be divided into several volumes. Considerable progress has been made in enzymology since the publication of the first edition (published as "Enzyme Handbook"): many enzymes are newly classified or reclassified. In the 2nd edition each entry is correlated with references and one or more source organisms. New datafields are created: "application" and "engineering" (for the properties of enzymes where the sequence has been changed). Altogether the amount of data has doubled so that the 2nd edition will consist of 39 volumes plus synonym index. This collection is an indispensable source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences.

The contrasting examples of microwave plasmas given in this volume demonstrate their capability of not only covering the totality of expressed needs in that particular field, but in many others. For example the ions and reactive neutral species, indispensable for the synergetic effects in etching and deposition processes can be used in metallurgical treatment, and for materials processing in general. They also have the ability to dissociate molecules and excite atoms as required in analytical chemistry where the information on the constituent concentrations is obtained through optical spectroscopy or mass spectrometry. Finally, microwave plasmas can supply the photons for laser and lighting applications. It is noteworthy that microwave plasmas cover an impressive pressure range of eight orders of magnitude from 10-3 Pa (10-5 torr) to above atmospheric pressure. The versatility of microwave plasmas, their moderate cost, and their ease of implementation particularly appeal to the industrial entrepreneur.

As well as providing a review of current developments, the work proposes a synthesis on microwave discharges, laying out the corresponding physical references without developing too much plasma theory. It will be of interest both to the user, who may not be overly concerned about plasma science, and to the plasma expert, who may wish to redirect his interest towards plasma applications, such as materials processing.

A comprehensive source of information about modern drying technologies that uniquely focus on the processing of pharmaceuticals and biologicals Drying technologies are an indispensable production step in the pharmaceutical industry and the knowledge of drying technologies and applications is absolutely essential for current drug product development. This book focuses on the application of various drying technologies to the processing of pharmaceuticals and biologicals. It offers a complete overview of innovative as well as standard drying technologies, and addresses the issues of why drying is required and what the critical considerations are for implementing this process operation during drug product development. Drying Technologies for Biotechnology and Pharmaceutical Applications discusses the state-of-the-art of established drying technologies like freeze- and spray- drying and highlights limitations that need to be overcome to achieve the future state of pharmaceutical manufacturing. The book also describes promising next generation drying technologies, which are currently used in fields outside of pharmaceuticals, and how they can be implemented and adapted for future use in the pharmaceutical industry. In addition, it deals with the generation of synergistic effects (e.g. by applying process analytical technology) and provides an outlook toward future developments. -Presents a full technical overview of well established standard drying methods alongside various other drying technologies, possible improvements, limitations, synergies, and future directions -Outlines different drying technologies from an application-oriented point of view and with consideration of real world challenges in the field of drug product development -Edited by renowned experts from the pharmaceutical industry and assembled by leading experts from industry and academia Drying Technologies for Biotechnology and Pharmaceutical Applications is an important book for pharma engineers, process engineers, chemical engineers, and others who work in related industries.

CONTENTS - Preface - Contributors - Abbreviations - Introduction - I. Antiperspirants and Deodorants - II. Hair Products - III. Bath Preparations - IV. Face and Hand Cleaners - V. Face, Eye, and Body Makeup - VI. Creams and Lotions - VII. Mouth Preparations - VIII. Perfumes, Colognes, and Powders - IX. Shaving Preparations - X. Sunscreen Products - XI. Miscellaneous - Appendix - pH Values - pH Ranges of Common Indicators - International Atomic Weights - Temperature Conversion Tables - Incompatible Chemicals - Safety in the Laboratory or Home Workshop - General Laboratory Equipment - Aerosols - Trademark Chemical Manufacturers - Trademark Chemicals - Index - PREFACE - The growth of the cosmetic industry in the U.S.A. is a prime example of the dynamics of industry. From 1914 to 1966 the retail cosmetic sales within the U.S.A. went from almost $40 million to well over $3 billion. Part of the reason for this upsurge can be attributed to the increased interest shown by men in cosmetic products such as various shaving creams, colognes, hair tonics and conditioners. Because of the importance of this field of chemical science, it seemed pertinent to produce a chemical formulary specializing in cosmetic preparations of all types. The formulas and data in this book have all been contributed within the past twelve months by the companies listed on page iv They are printed as contributed and thus there are variations in manner of presentation. The formulas included here are of an experimental nature and are intended to be used as starting points for the industrial chemist, and for those who wish to experiment in their own right. Many of the formulas can serve as successful products without any alterations required. However, once the chemist has familiarized himself with the formulas as they stand, the adventure of individual experimentation begins. All data is based on U.S. Specification and practice, but readers in other countries should not find it difficult to adapt the formulas for their own use.

Microbial Lipids: Processes, Products, and Innovations brings together experienced authors on microbial lipids bioproduction, introducing the reader to key aspects from lipid chemistry and biochemistry to industrial production by fungi, yeast and microalgae. Intended for professionals in industry-oriented research and development, this volume also describes lipid production using synthetic media and agroindustry residues and discusses the potential of integration of microbial lipids in biorefineries, towards a circular economy. With a market of US$ 7 billion, oils and fats are one of the most important classes of natural products, with applications in food, feed, nutraceuticals, cosmetics, biofuel, and oleo chemistry. Primary sources include plants, animals and fish. However, specialty lipids such as oils rich in omega-3 and -6 fatty acids have limited sources and productivity. Microbial oils are gaining space in the global market as green - and even vegan - alternatives to traditional sources. Microorganisms also have high productivity and metabolic plasticity which makes it promising sources of new products.

This book provides in-depth coverage on the latest concepts, systems, and technologies that are being utilized in biorefineries for the production of biofuels and value-added commodities. Written by internationally recognized experts, the book provides a comprehensive overview of pretreatment technology for biorefineries and biofuels, enzymatic hydrolysis and fermentation technology for biofuel production, and lignin valorization for developing new products from waste lignin. The book will be a valuable resource for researchers and professionals working in process engineering, product engineering, material science, and systems and synthetic biology in the fields of biorefining, biofuel, biomaterials, environmental waste utilization, and biotechnology.

Designer Microbial Cell Factories: Metabolic Engineering and Applications, the latest release in the Current Developments in Biotechnology and Bioengineering series, provides a detailed overview of the biotechnological approaches and strategies used to generate engineered microbes and to facilitate the acceleration, modulation and diversion of metabolic pathways to get desired output such as production of value-added compound or biodegradation of xenobiotic pollutant. The book also highlights applied aspects of designer microbes in fields as diverse as agriculture, pharmaceuticals and bioremediation. Designer microbes generated through reprogramming the microbial cell factories (MCFs) provide an edge over their natural counterparts in terms of increased molecular diversity and selective chemistry. These bugs are becoming instrumental in several areas, including agriculture, environment and human health. Engineering microbes through directed evolution not only gives freedom from evolutionary constrains but also allow introduction of regulated and foreseeable functions into MCFs.

This thesis presents a simple, yet highly effective surface engineering solution that uses non-covalent binding peptides to control the autophagy-inducing activity of nanomaterials and nanodevices. The author presents RE-1, a short synthetic peptide that sequence-specifically binds to lanthanide (LN) oxide and upconversion nanocrystals with high affinity, which was discovered using an innovative phage display approach. RE-1 effectively inhibits the autophagy-inducing activity and toxicity of these nanocrystals by forming a stable coating layer on the surface of the nanoparticles, and by reducing their sedimentation and cell interaction. RE- 1 and its variants provide a versatile tool for tuning cell interactions in order to achieve the desired level of autophagic response and are useful for the various diagnostic and therapeutic applications of LN-based nanomaterials and nanodevices.

Foaming with Supercritical Fluids, Volume Nine provides a comprehensive description of the use of supercritical fluids as blowing agents in polymer foaming. To this aim, the fundamental issues on which the proper design and control of this process are rooted are discussed in detail, with specific attention devoted to the theoretical and experimental aspects of sorption thermodynamics of a blowing agent within a polymer, the effect of the absorbed blowing agent on the thermal, interfacial and rheological properties of the expanding matter, and the phase separation of the gaseous phase, and of the related bubble nucleation and growth phenomena. Several foaming technologies based on the use of supercritical blowing agents are then described, addressing the main issues in the light of the underlying chemical-physical phenomena.

This book presents the fundamentals of the reservoir and interfacial engineering. The book systematically starts with the basics of primary, secondary and tertiary (enhanced) oil recovery and emphasizes on the theory of microbial-enhanced oil recovery (MEOR) and its potential toward recovery of oil in place. Different approaches of MEOR such as in-situ, ex-situ, and integration of chemical- and microbial-enhanced oil recovery (EOR) are discussed in detail. This book highlights the link between the effectiveness of MEOR and the local reservoir conditions, crude oil characteristics, and indigenous microbial community. The latest implementations of MEOR across the globe are highlighted as case studies to outline the potential as well as the scope of MEOR. Given the topics covered, this book will be useful for professionals and researchers working in the areas of petroleum science and engineering, chemical engineering, biotechnology, bioengineering, and other related fields.

Systems analysis for sustainability is an emerging discipline where technologies, processes or policies are evaluated comprehensively for sustainability. Trifold sustainability metrics such as technical feasibility, economic viability and environmental impacts are commonly used to assess sustainability. In addition to these metrics, it is important to consider resource sustainability, policies and social aspects for evaluating the sustainability of any proposed alternative. Green-Economy: Systems Analysis for Sustainability provides a theoretical background to perform such analyses and detailed case studies. The first part of this book introduces methods and tools to perform technical feasibility analysis, economic viability analysis, environmental impacts assessment, environmental risk assessment, resource sustainability assessment, policy and social aspects of technologies, general logic-based sustainability assessment for green products and introduces resilience thinking. The second part of the book focuses on case studies with an emphasis on solar energy, biofuels and bioproducts from across the globe.

This is a concise book with comprehensive information on coal and biomass ash generated from their combustion in thermal power plants. It presents detailed studies on ash generated from contrasting coal and biomass feedstocks, and provides a comparative evaluation of these different ashes in terms of their origin, properties, environmental hazards. Potential utilizations with specific advantages and disadvantages of the respective ashes are elaborated in detail, including some innovative means of ash utilization for value addition purposes. By addressing both the theory and commercial exploitation of these products, this book will be helpful for industrialists, academicians and researchers alike.

This book provides an updated and detailed overview on the recent developments of bioethanol technology. It looks at the historical perspectives, chemistry, sources and production of ethanol and discusses biotechnology breakthroughs and promising developments, its uses, advantages, problems, environmental effects and characteristics. In addition, it presents information about ethanol in different parts of the world and also highlights the challenges and future of ethanol. The first edition of this book was published as a SpringerBriefs in 2013. Since then, many new developments have taken place in the last six years. This new edition will highlight the evolution in bioethanol development from first-generation production to the futuristic fourth-generation bioethanol production, the various constraints and challenges involved, and the scope for development. This book caters to the audience who are interested in alternative transportation fuels which are both biodegradable and sustainable to the environment.

This book presents recent advances in the use of ionic liquids in medicine and pharmaceutics with particular emphasis on addressing critical pharmaceutical challenges, including the low solubility, polymorphism, and bioavailability of drugs. It also provides insights into the development of the biologically functionalized ionic liquids suitable for medical and pharmaceutical applications. Ionic liquids have been used as potential solvents or materials in the fields of pharmaceutical drug delivery and formulations because of their unique and tunable physicochemical and biological properties. Readers find explanations of the diverse approaches to the application of ionic liquids in drug solubility, active pharmaceutical ingredient (API) formulation, and drug delivery systems, such as topical, transdermal, and oral delivery, with particular emphasis on recent developments. Particular attention is given to the development of ionic liquid-assisted effective drug delivery techniques for sparingly soluble or insoluble drug molecules. This book also discusses the biological activities of ionic liquids for possible applications in drug formulation and drug delivery systems. Scientists in disciplines such as chemistry, biology, and pharmaceutics find this book instructive and informative for developing ionic liquid-based drug formulations or drug delivery systems.

Process Safety Calculations, Second Edition remains to be an essential guide for students and practitioners in process safety engineering who are working on calculating and predicting risks and consequences. The book focuses on calculation procedures based on basic chemistry, thermodynamics, fluid dynamics, conservation equations, kinetics and practical models. It provides helpful calculations to demonstrate compliance with regulations and standards, such as Seveso directive(s)/COMAH, CLP regulation, ATEX directives, PED directives, REACH regulation, OSHA/NIOSH and UK ALARP, along with risk and consequence assessment, stoichiometry, thermodynamics, stress analysis and fluid-dynamics. This fully revised, updated and expanded second edition follows the same organization as the first, including the original three main parts, Fundamentals, Consequence Assessment and Quantitative Risk Assessment. However, the latter part is significantly expanded, including an appendix consisting of five fundamental thematic areas belonging to the risk assessment framework, including in-depth calculations methodologies for some fundamental monothematic macro-areas of process safety.

Nanotechnology in Cancer Management: Precise Diagnostics toward Personalized Health Care provides a well-focused and comprehensive overview of technologies involved in early stage cancer diagnostics via the detection of various cancer biomarkers, both in-vitro and in-vivo. The book briefly describes the advancement in cancer biomarker research relating to cancer diagnostics, covering fundamental aspects of various techniques, especially transduction methodologies, such as electrochemical, optical, magnetic, etc. In addition, it describes approaches on how to make options cost-effective, scalable for clinical application, and user-friendly. Advancements in technology related to device miniaturization, performance improvement and point-of-care applications round out discussions. Final sections cover future challenges, the prospects of various techniques, and how the introduction of nanotechnology in cancer management in a personalized manner is useful.

Natural Polymers-Based Green Adsorbents for Water Treatment focuses on the recent development of novel polymeric adsorbents that are green and eco-friendly or biodegradable in nature. The book reviews the synthesis, properties and adsorption applications of natural and green polymer-based adsorbents. It discusses adsorption processes in biopolymer systems, remediation technologies developed to remove environmental pollutants, the usage of natural polymer-based cost-effective and green novel adsorbent materials for the removal of organic and inorganic contaminants, and the efficiency of functionalized polymers, nanosorbents, hydrogels, composites, graft copolymers in the sorption of various pollutants from the environment as well as from the industrial effluents. Researchers working on environmental remediation need a single book, where all data on natural and green adsorbents for water treatment are discussed comprehensively. Natural Polymers-Based Green Adsorbents for Water Treatment addresses this need by providing world-wide leading experts' observations and research. So, this book is a valuable reference for early-career scientist, academic researchers and graduate students in chemical engineering and material science.

Nanostructured Photocatalysts: From Fundamental to Practical Applications offers a good opportunity for academic, industrial researchers and engineers to gain insights on the fundamental principles and updated knowledge on the engineering aspects and various practical applications of photocatalysis. This book comprehensively and systematically reviews photocatalytic fundamental aspects, ranging from reaction mechanism, kinetic modeling, nanocatalyst synthesis and design, essential material characterization using advanced techniques, and novel reactor design and scale-up. Future perspectives, techno-economical evaluation and lifecycle assessment of photocatalytic processes are also provided. Finally, a wide range of practical, important and emerging photocatalytic applications, namely wastewater treatment, air pollution remediation, renewable and green energy generation, and vital chemical production are thoroughly covered, making this book useful and beneficial for engineers, scientists, academic researchers, undergraduates and postgraduates.