Process integration has been one of the most active research fields in Biochemical Engineering over the last decade and it will continue to be so if bioprocessing is to become more rational, efficient and productive. This volume outlines what has been achieved in recent years. Written by experts who have made important contributions to the European Science, Foundation Program on Process Integration in Biochemical Engineering, the volume focuses on the progress made and the major opportunities, and in addition on the limitations and the challenges in bioprocess integration that lie ahead. The concept of bioprocess integration is treated at various levels, including integration at the molecular, biological, bioreactor and plant levels, but also accounting for the integration of separation and mass transfer operations and biology, fluid dynamics and physiology, as well as basic science and process technology.

CONTENTS - 1. INTRODUCTION - 2. ANIMAL FATS AND OILS - 3. VEGETABLE FATS AND OILS - 4. FATTY ACIDS-FATTY ALCOHOLS-GLYCEROL - 5. SURFACTANTS AND SURFACE ACTIVITY - 6. PRODUCTION OF FATS AND OILS - 7. SOAP MANUFACTURE - 8. SYNTHETIC DETERGENTS - 9. ANALYSIS OF OILS AND DETERGENTS - INDEX - Preface - Presented in this book are quantities of data, gathered during many years in my practice of chemistry, either as resident chemist in manufacturing plants, or as a consultant to the soap and related industries. The style is didactic and such that it may readily be understood by non-technical personnel. Involved theoretical and technical discussions have been avoided. As far as possible, references have been included at the end of each chapter. Although much of the information contained in this work is well within my own experience, much of it has been gleaned also from manufacturers' technical bulletins or through private correspondence. Many patents have been cited, merely as examples of products discussed; this is not to be construed as recommending the infringement of any such patents. The various formulations are presented in good faith, but no warranty is given, nor is freedom from any patent to be inferred. With a little ingenuity on the part of the reader, many useful and efficient products may be made along the lines discussed, without in any way infringing on patented products. Because of numerous factors affecting results, all the formulations cited herein, although believed to be reliable (most of them having emanated from the greatest laboratories in the world) should be tested thoroughly. It is especially recommended that manufacturers make their own tests to determine the suitability of the formulations, for the specific applications intended. I am indebted to the manufacturers of the many chemicals named in the book, for information which I gathered either from direct correspondence or from their technical bulletins; also for their many samples with which I compounded some of the formulas. Special mention should be made of those companies that supplied photographs of equipment and installations depicting various processes. I have tried to include all information pertinent to each formula, and credit has been given to all identified suppliers, so that additional information, if needed, may be obtained from the manufacturers of the basic materials used. Finally, I am grateful to the publishers for valuable assistance in the organization and presentation of my quantities of material which now comes out as not merely a second edition of my Oil, Fat, and Soap, but as a much more comprehensive new book.|CONTENTS - 1. AEROSOLS - 2. BACTERICIDES-FUNGICIDES - SANITIZERS - 3. CLEANERS FOR HOUSEHOLD AND INDUSTRY - 4. CARE OF FLOORS - 5. LAUNDERING AND DRY CLEANING - 6. TREATMENT OF METALS - 7. PESTICIDES - 8. MISCELLANEOUS - BIBLIOGRAPHY - APPENDIX - Glossary - Suppliers of Materials and Equipment - Useful Tables - Patents - Periodicals of Interest - Associations Related to the Industry - INDEX -

There is hardly a technical library in the world in which the volumes of the Chemical Formulary (Volumes 1-34) do not occupy a prominent place. It does not duplicate any of the formulas included in previous volumes, but lists a wide array of modern and salable products from all branches of the chemical industries. An excellent reference for formulation problems. - CONTENTS - I. Introduction - II. Adhesives - III. Beverages and Foods - IV. Cosmetics - V. Coatings - VI. Detergents - VII. Drugs - VIII. Metal Treatments - IX. Polishes - X. Elastomers, Polymers and Resins - XI. Miscellaneous - Appendix - Index - PREFACE - Chemistry, as taught in our schools and colleges, concerns chiefly synthesis, analysis, and engineering-and properly so. It is part of the right foundation for the education of the chemist. Many a chemist entering an Industry soon finds that most of the products manufactured by his concern are not synthetic or definite complex compounds, but are mixtures, blends, or highly complex compounds of which he knows little or nothing. The literature in this field, if any, may be meager, scattered, or obsolete. Even chemists with years of experience In one or more Industries spend conslderable time and effort in acquainting themselves with any new field which they may enter. Consulting chemists similarly have to solve problems brought to them from industries foreign to them. There was a definite need for an up-to-date compilation of formulae for chemical compounding and treatment. Since the fields to be covered are many and varied, an editorial board of chemists and engineers engaged in many industries was formed. Many publications, laboratories, manufacturing firms, and Individuals have been consulted to obtain the latest and best information. It is felt that the formulas given in this volume will save chemists and allied workers much time and effort.

This book presents all information necessary to understand the functioning of a slurry loop reactor for the polymerisation of ethylene into high density polyethylene, and to operate it accordingly. All discussions are based on experimental data from the operation of full scale commercial loop reactors. Methods for off-line modelling and scaling-up from lab to full scale are included, as well as the answers to important questions on the running of two loop reactors in series. Building knowledge from full scale industrial experience. This highly accessible book makes one understand the functioning of slurry loop reactors for the polymerisation of ethylene, and how to operate them. Its methods include off-line modelling, scaling-up and running reactors in series. It is inspiring for all production and process engineers, showing, for the first time, how with full scale reactor data the link is made between firm basic theory and the most practical operating guidelines.

Both volumes of this dictionary consists of some 63,000 and over 100,000 translations from all the main areas of chemistry and chemical technology including: Analytical Chemistry, Biochemistry, Biotechnology, Chromatography, Colour, Inorganic Chemistry, Laboratory techniques, Metallurgy & Treatment, Organic chemistry, Physical chemistry, Plastics, Process engineering, Spectroscopy and Industrial Chemistry.

Presenting extensive, recent advances in the field of hydrocracking-including new catalytic materials, reaction mechanisms and pathways, as well as new hydrocracking processes and applications-this unified reference covers in detail both catalysts and processes. Analyzing every important area related to the subject, Hydrocracking Science and Technology describes the petroleum refining process and the history of hydrocracking catalyst composition, preparation, and manufacturing methods deactivation and reactivation the correlation between catalyst composition and performance catalyst characterization and reclamation techniques reaction mechanisms and much more

Providing a grounding in the chemistry and chemical technology of lubricants, this book contains comprehensive coverage of the industry from the viewpoint of a chemist. It deals with traditional and synthetic base oils, the additives in common use, major applications and environmental aspects. The book is intended for chemists and chemical engineers working with lubricants, and as a source of reference for research and academic institutions and advanced students.

Contents - Adhesives - Cleaning Preparations - Cosmetics and Perfumes - Food Products - Furniture and Metal Polishes - Inks - Insecticides and Rodenticides - Miscellaneous - Paints - Pharmaceutical and Proprietary Preparations - Stain Removers - Veterinary Preparations - Tests: Various - Appendix A: Weights and Measures; Conversion Tables - Appendix B: Composition of Foods - Appendix C: Atomic Weights; Bibliography; Suppliers - Index -

Written by more than 40 world renowned authorities in the field, this reference presents information on plant design, significant chemical reactions, and processing operations in industrial use - offering shortcut calculation methods wherever possible.

This thesis explores the ability of M. maripaludis to capture and convert CO2 to methane in the presence of free nitrogen, and offers a consolidated review of the metabolic processes and applications of M. maripaludis. Further, it develops, validates and analyzes the first genome-scale metabolic model (iMM518) of M. maripaludis. Readers will discover, for the first time, the impact of nitrogen fixation on methane production. As such, the thesis will be of interest to researchers working on M. maripaludis, biofuels and bioenergy, systems biology modeling and its experimental validation, estimation of maintenance energy parameters, nitrogen fixing microbes, and bioremediation.

This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.

Expanded bed adsorption chromatography is a novel processing technique for the purification of biomolecules, combining clarification, concentration and initial purification in one step. By such an integration it is possible to reduce the number of steps in the purification process, to shorten the processing time and to improve the yields. The technology is new, and interesting developments have taken place concerning the adsorbents, the processing technology and potential applications. Both small-scale laboratory processes and larger industrial processes are being developed. Expanded bed chromatography is one of the most exciting new developments in downstream processing in recent years. The technology will be a standard procedure when new biotechnological processes are being developed.

The areas we deal with in biochemical engineering have expanded to include many various organisms and humans. This book has gathered together the information of these expanded areas in biochemical engineering in Japan. These two volumes are composed of 15 chapters on microbial cultivation techniques, metabolic engineering, recombinant protein production by transgenic avian cells to biomedical engineering including tissue engineering and cancer therapy. Hopefully, these volumes will give readers a glimpse of the past and also a view of what may happen in biochemical engineering in Japan.

"WHAT DOES NOT NEED TO BE BIG, WILL BE SMALL," a word by an engineer at a recent conference on chips technology. This sentence is particularly true for chemistry. Microfabrication technology emerged from microelectronics into areas like mechanics and now chemistry and biology. The engineering of micron and submicron sized features on the surface of silicon, glass and polymers opens a whole new world. Micromotors smaller than human hair have been fabricated and they work fine. It is the declared goal of the authors to bring these different worlds together in this volume. Authors have been carefully chosen to guarantee for the quality of the contents. An engineer, a chemist or a biologist will find new impulses from the various chapters in this book.

This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases. Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs. This unique book addresses new developments and is designed for graduate level and professional research purposes.

Purification of Laboratory Chemicals: Part One, Physical Techniques, Chemical Techniques, Organic Chemicals, Ninth Edition describes contemporary methods for the purification of chemical compounds. The work includes tabulated methods taken from literature for purifying thousands of individual commercially available chemical substances. To help in applying this information, the more common processes currently used for purification in chemical laboratories and new methods are discussed. For dealing with substances not separately listed, another chapter is included, setting out the usual methods for purifying specific classes of compounds. Laboratory workers, whether carrying out research or routine work, will invariably need to consult this book. Apart from the procedures described, the large amount of physical data about listed chemicals is essential. This fully updated, revised and expanded new edition includes the purification of many new substances that have been available commercially since 2017, along with previously available substances which have found new applications.

Biocatalysis in Oil Refining focuses on petroleum refining bioprocesses, establishing a connection between science and technology.
The micro organisms and biomolecules examined for biocatalytic purposes for oil refining processes are thoroughly detailed. Terminology used by biologists, chemists and engineers is brought into a common language, aiding the understanding of complex biological-chemical-engineering issues. Problems to be addressed by the future R&D activities and by new technologies are described and summarized in the last chapter.
* Updated references
* Studying bioprocessing problems, looking at opportunities for improvements and technology developments

The suppression of apoptosis by the IGF system is critical for normal cell development, proliferation, differentiation and motility. Aberrations in IGF signalling mechanisms contribute to cell transformation, tumour progression and metastasis. Many questions remain to be answered as to how exactly the IGF system mediates its effects both in normal and tumour cells and how the IGF-1R interacting proteins and downstream signalling cascades are regulated. The importance of the IGF system is underscored by the significant interest in the development of anti-IGF therapies for IGF sensitive cancers. Future developments in cancer therapy are likely to focus on methods to target these therapies to diseased but not normal cells. 14. Acknowledgements We would like to thank Kurt Tidmore for preparing the illustrations. The Health Research Board of Ireland and Science Foundation Ireland are grateful acknowledged for funding. 15. References Adamo M., Roberts C. T., Jr. and LeRoith D. (1992) How distinct are the insulin and insul- like growth factor I signalling systems? Biofactors 3, 151-7. Adams T. E., Epa V. C., Garrett T. P. and Ward C. W. (2000) Structure and function of the type 1 insulin-like growth factor receptor. Cell Mol Life Sci 57, 1050-93. Adler V., Polotskaya A., Wagner F. and Kraft A. S. (1992) Affinity-purified c-Jun ami- terminal protein kinase requires serine/threonine phosphorylation for activity. J Biol Chem 267, 17001-5.