Thermodynamic Processes 2 is devoted to the study of equilibrium between phases in the case of the four changes of physical state: fusion, boiling or vaporization, sublimation and allotropy or transition. It also includes a section that addresses energy s relationship to the zero sum aspect of exergy and thermal cycles. This second volume presents scientific and technical examples - both theoretical and industrial - which are the result of a careful selection, accrued over more than three decades of teaching thermodynamics and in collaboration with the industry sector. The didactic exercises and the practical problems are entirely dedicated to the understanding of this science, and the potential applications for the industrial world. This book is a tool for work and reflection essential for the student in training, as well as the engineer or experienced researcher.

It is well known that the world is becoming increasingly globalized. Globalization implies the continual movement of people, money, products, technology, and information across national boundaries over time. This movement can have a huge impact on communication, jobs, business, politics, and technology. Not surprisingly, globalization has generated both challenges and opportunities for the chemistry enterprise. This book focuses on the transnational opportunties for the global chemistry enterprise. The book is divided into two sections: 1) Transnational Study, Research and Careers, and 2) International Entrepreneurship. Because the emphasis of this book is on internationalization and globalization, anyone interested in the global aspects of the chemistry enterprise will find the book useful. The topics include future chemistry curriculum, global preparedness of students, international education exchange and research opportunities, study-abroad programs, and international research collaborations.

Separation and characterization of materials is an essential step in the advancement of science and technology. The need for separation and characterization could arise from wishes to obtain purified samples with less contaminants, requirements for quality control of materials for downstream applications, or needs to identify structures and conformations of active species present in the applications. The types of materials encountered in applications are diverse, from synthetic polymers and biological derived biopolymers to micro or submicro particles and various conjugated or self-assembled nanomaterials. This makes the task of separation and characterization challenging. There is no one-size-fits-all approach. Scientists, whether working in academia or in industries, are constantly facing new challenges. Communication between scientists is essential for keeping each other updated on developments in the field. This was the motivation for organizing the symposium on "Recent Progress in Separation of Macromolecules and Particulates" at the 2017 Spring National American Chemical Society (ACS) Meeting in San Francisco. Symposiums based on such a theme have been organized several times in ACS meetings as well as in other settings, but no such symposium books have been published. Hence, the editors decided to put together this symposium book, based on the talks presented at the symposium, in the hope that knowledge shared at the meeting can be shared more broadly within the community and beyond.

In the 1980's sonochemistry was considered to be a rather restricted branch of chemistry involving the ways in which ultrasound could improve synthetic procedures, predominantly in heterogeneous systems and particularly for organometallic reactions. Within a few years the subject began to expand into other disciplines including food technology, environmental protection and the extraction of natural materials. Scientific interest grew and led to the formation of the European Society of Sonochemistry in 1990 and the launch of a new journal Ultrasonics Sonochemistry in 1994. The subject continues to develop as an exciting and multi-disciplinary science with the participation of not only chemists but also physicists, engineers and biologists. The resulting cross-fertilisation of ideas has led to the rapid growth of interdisciplinary research and provided an ideal way for young researchers to expand their knowledge and appreciation of the ways in which different sciences can interact. It expands scientific knowledge through an opening of the closed doors that sometimes restrict the more specialist sciences. The journey of exploration in sonochemistry and its expansion into new fields of science and engineering is recounted in "Sonochemistry Evolution and Expansion" written by two pioneers in the field. It is unlike other texts about sonochemistry in that it follows the chronological developments in several very different applications of sonochemistry through the research experiences of the two authors Tim Mason and Mircea Vinatoru. Designed for chemists and chemical engineers Written by two experts and practitioners in the subject Volume 1 covers the historical background and evolution of sonochemistry Volume 2 explains the wider applications and expansion of the subject VOLUME 1 Fundamentals and Evolution This volume traces the evolution of sonochemistry from the very beginning when the effects of acoustic cavitation were first reported almost as a scientific curiosity. The major developments of the subject from the 1980's are described by the authors who became active participants in the field during that period. A chapter is devoted to ultrasonically assisted extraction (UAE) which illustrates the different ways in which sonochemical technologies can be applied in both batch and flow modes leading to the development of large-scale processing. The chapter on environmental protection shows the wide range of applications of sonochemistry in this important field for both biological and chemical decontamination.

This textbook introduces the elementary basics of hydrochemistry with special focus on reaction equilibria in aquatic systems and their mathematical description. Topics discussed in this textbook include: structure and properties of water, concentration measures and activities, colligative properties, basics of chemical equilibria, gas-water partitioning, acid/base reactions, precipitation/dissolution, calco-carbonic equilibrium, redox reactions, complex formation, and sorption. Examples within the text as well as problems to be solved by the reader support the acquisition of knowledge. Complete and detailed solutions to the problems are given in a separate chapter.

This book covers intentional design aspects for combinations of drugs, single-molecule hybrids with potential or actual multiple actions, pro-drugs which could yield multiple activity outcomes, and future possibilities. The approach of the book is interdisciplinary, and it provides greater understanding of the complex interplay of factors involved in the medicinal chemistry design and laboratory development of multiply active antibacterials. The scope of the book appeals to readers who are researching in the field of antibacterials using the approach of medicinal chemistry design and drug development.

This is the second of two volumes that together provide an overview of the latest advances in the generation and application of digital twins in bioprocess design and optimization. Both processes have undergone significant changes over the past few decades, moving from data-driven approaches into the 21st-century digitalization of the bioprocess industry. Moreover, the high demand for biotechnological products calls for efficient methods during research and development, as well as during tech transfer and routine manufacturing. In this regard, one promising tool is the use of digital twins, which offer a virtual representation of the bioprocess. They reflect the mechanistics of the biological system and the interactions between process parameters, key performance indicators and product quality attributes in the form of a mathematical process model. Furthermore, digital twins allow us to use computer-aided methods to gain an improved process understanding, to test and plan novel bioprocesses, and to efficiently monitor them. This book focuses on the application of digital twins in various contexts, e.g. computer-aided experimental design, seed train prediction, and lifeline analysis. Covering fundamentals as well as applications, the two volumes offers the ideal introduction to the topic for researchers in academy and industry alike.

Process engineering emerged at the beginning of the 20th Century and has become an essential scientific discipline for the matter and energy processing industries. Its success is incontrovertible, with the exponential increase in techniques and innovations. Rapid advances in new technologies such as artificial intelligence, as well as current societal needs - sustainable development, climate change, renewable energy, the environment - are developments that must be taken into account in industrial renewal. Process Engineering Renewal 1 - the first volume of three - focuses on training, demonstrating the need for innovation in order for the field to have a framework that is sustainable, in a highly changeable world.

Virtual Modelling and Rapid Manufacturing presents essential research in the area of Virtual and Rapid Prototyping. It contains reviewed papers that were presented at the 2nd International Conference on Advanced Research in Virtual and Rapid Prototyping, held at the School of Technology and Management of the Polytechnic Institute of Leiria, Portugal, from September 28 to October 1, 2005. The volume covers a wide range of topical subjects, such as medical imaging, reverse engineering, virtual reality and prototyping, biomanufacturing and tissue engineering, advanced rapid prototyping technologies and micro-fabrication, biomimetics and materials, and concurrent engineering

The Handbook of Carbohydrate Engineering provides an overview of the basic science, theory, methods, and applications of this broad, interdisciplinary field. The text provides background information along with practical knowledge for current and future research methodologies used in the characterization and synthesis of various carbohydrates. This multidisciplinary perspective involves aspects of basic biology, synthetic chemistry, enzymology, complex instrumentation, and sophisticated modeling. The book presents the fundamentals of carbohydrate engineering, addressing concepts in structure, biosynthesis, and biological functions for a variety of carbohydrates with a particular emphasis on mammalian glycoproteins and their N-linked oligosaccharides, glycolipids, sialic acid, as well as polysaccharides from both eukaryotes and bacteria. It describes glycosylation processes found in nature and surveys methods to manipulate these metabolic systems in living cells both for the improved production of carbohydrates and to give these molecules novel properties. Subsequent sections discuss the various methods of purification, synthesis, modification, and analysis used to create and manipulate carbohydrates in the laboratory; these approaches include chemical-enzymatic synthesis, small-molecule cell-based strategies, as well as complete chemical synthesis. The Handbook of Carbohydrate Engineering also focuses on practical applications for carbohydrates. It emphasizes methods to characterize glycosylation pathways and expounds upon the role of carbohydrates in health and disease, a significant - and rapidly growing - area of research. World-renowned experts discuss biomedical applications, including the development of vaccines, therapeutics, glycomimetics, antibody engineering, drug delivery, tissue engineering and organ regeneration, and diagnostic agents. Several chapters also cover important applications in agriculture, industry, food technology, and envir

This newly designed and enlarged edition offers an up-to-date presentation of biosensor development and modeling from both a chemical and a mathematical point of view. An entire new chapter in particular is dedicated to optimal design of biosensors. Two more new chapters discuss biosensors which utilize microbial cells and are based on carbon nanotubes respectively. All the other chapters have been revised and updated. The book contains unique modeling methods for amperometric, potentiometric and optical biosensors based mainly on biocatalysts . It examines processes that occur in the sensors' layers and at their interface, and it provides analytical and numerical methods to solve equations of conjugated enzymatic (chemical) and diffusion processes. The action of single enzyme as well as polyenzyme biosensors and biosensors based on chemically modified electrodes is studied. The modeling of biosensors that contain perforated membranes and multipart mass transport profiles is critically investigated. Furthermore, it is fully described how signals can be biochemically amplified, how cascades of enzymatic substrate conversion are triggered, and how signals are processed via a chemometric approach and artificial neuronal networks. The results of digital modeling are compared with both proximal analytical solutions and experimental data.

The book presents a unique view of failure analysis of high technology devices. It describes capabilities and limitations of many analytical techniques and testing paths and decisions best followed in example failure analysis studies.

Chemical reaction engineering is concerned with the exploitation of chemical reactions on a commercial scale. It's goal is the successful design and operation of chemical reactors. This text emphasizes qualitative arguments, simple design methods, graphical procedures, and frequent comparison of capabilities of the major reactor types. Simple ideas are treated first, and are then extended to the more complex.

Many elements and inorganic compounds play an extraordinary role in daily life for numerous applications, e. g., construction materials, inorganic pigments, inorganic coatings, steel, glass, technical gases, energy storage and conversion materials, fertilizers, homogeneous and heterogeneous catalysts, photofunctional materials, semiconductors, superconductors, soft- and hard magnets, technical ceramics, hard materials, or biomedical and bioactive materials. The present book is written by experienced authors who give a comprehensive overview on the many chemical and physico-chemical aspects related to application of inorganic compounds and materials in order to introduce senior undergraduate and postgraduate students (chemists, physicists, materials scientists, engineers) into this broad field.

Many elements and inorganic compounds play an extraordinary role in daily life for numerous applications, e. g., construction materials, inorganic pigments, inorganic coatings, steel, glass, technical gases, energy storage and conversion materials, fertilizers, homogeneous and heterogeneous catalysts, photofunctional materials, semiconductors, superconductors, soft- and hard magnets, technical ceramics, hard materials, or biomedical and bioactive materials. The present book is written by experienced authors who give a comprehensive overview on the many chemical and physico-chemical aspects related to application of inorganic compounds and materials in order to introduce senior undergraduate and postgraduate students (chemists, physicists, materials scientists, engineers) into this broad field.

Many elements and inorganic compounds play an extraordinary role in daily life for numerous applications, e. g., construction materials, inorganic pigments, inorganic coatings, steel, glass, technical gases, energy storage and conversion materials, fertilizers, homogeneous and heterogeneous catalysts, photofunctional materials, semiconductors, superconductors, soft- and hard magnets, technical ceramics, hard materials, or biomedical and bioactive materials. The present book is written by experienced authors who give a comprehensive overview on the many chemical and physico-chemical aspects related to application of inorganic compounds and materials in order to introduce senior undergraduate and postgraduate students (chemists, physicists, materials scientists, engineers) into this broad field.

This fully updated edition provides a broad approach to the surface analysis of polymers being of high technological interest. Modern analytical techniques, potential applications and recent advances in instrumental apparatus are discussed. The self-consistent chapters are devoted to spectroscopic and microscopic techniques which represent powerful tools for the characterization of morphology and chemical, physical, mechanical properties of polymer surfaces, interfaces, and thin fi lms. Selection of techniques which can properly address very shallow depth of surfaces, spanning from few angstroms to tens of nanometers Interaction of polymer surfaces with their surroundings is pointed out as a critical issue for specifi c applications

The tumour microenvironment is increasingly recognized as an important contributor to cancer progression and treatment. However, most cancer studies continue to be performed in 2D tissue culture dishes that do not capture the characteristics of the tumour niche. This book provides an introduction to the rich chemical, topographical, and mechanical cues in the tumour microenvironment and then introduces readers to bioengineering strategies, including scaffold design and synthesis, chemical signalling and delivery, and co-culture, microfluidics, and organ-on-a-chip tools that can be used to mimic tumour microenvironment features. This book also includes discussion of emerging imaging methods compatible with tumour microenvironment mimicking biomaterials and discusses applications of such models in immuno-oncology, metastasis, and drug screening. Edited by two leaders in the field, this book will appeal to graduate students and researchers working in biomaterials science, chemical and biomedical engineering departments.

This book focuses on the development of stapled peptides, a novel molecular modality used to regulate aberrant intracellular protein-protein interactions (PPIs). The author designs and presents a novel helical peptide stabilization methodology by constructing a chiral cross-linker moiety, namely "chiral center induced peptide helicity (CIH)". The book demonstrates that a precisely positioned carbon chiral center on tether can decisively determine the secondary structure of a peptide, and that the R-configured peptide is helical, while the S-configured peptide is non-helical. Further, it reports that helicity-enhanced R isomer peptides displayed significantly enhanced cell permeability and target binding affinity, as well as tumor inhibition efficiency, in comparison to S isomer peptides. The book will not only advance readers' understanding of the basic principle of stapled peptides, but also accelerate the clinical transformation of stapled peptide drugs.

This book provides updated information about applications of ion chromatography (IC) in food science, such as food quality control, food authentication and analysis of residues in certain food products. Among liquid chromatography methods, IC can be considered one of the most valuable analytical tools, an advantageous environmentally friendly technique able to provide a convenient determination of various analytes such as anions, cations, organic acids, carbohydrates, amines, amino acids, aminoglycosides, proteins, peptides, etc. Recent developments such as in-line eluent generation systems, capillary IC and combustion IC, are also described. The book is intended to serve as an organized resource for students, researchers and food analysts, but can be a relevant support for researchers from related fields. It highlights that IC can be even more powerful and effi cient when more complex equipment is available, while proper knowledge empowers the user to obtain relevant data from this.

Tellurium, a well-known chalcogen, finds potential applications in various fields from chemistry to other branches of science such as nanotechnology and macromolecular science. However, its safety must also be taken into consideration when exploring its industrial applications. This book explores the breadth of tellurium's applications, outlines strategies for industrial use, and describes the safety concerns of this element.

From disease marker identification to accelerated drug development, Protein Arrays, Biochips, and Proteomics offers a detailed overview of current and emerging trends in the field of array-based proteomics. This reference focuses on innovations in protein microarrays and biochips, mass spectrometry, high-throughput protein expression, protein-protein interactions, structural proteomics, and the proteomic marketplace for comprehensive understanding of past, present, and future proteomic research. Offering an abundance of figures and charts, the book compiles a wide variety of technologies and applications ranging from functionalized chip surfaces to strategies for protein expression.

The Definitive Guide to Chemical Reaction Engineering Problem-Solving -- With Updated Content and More Active Learning For decades, H. Scott Fogler's Elements of Chemical Reaction Engineering has been the world's dominant chemical reaction engineering text. This 6th Edition and integrated Web site deliver a more compelling active learning experience than ever before. Using sliders and interactive examples in Wolfram, Python, POLYMATH, and MATLAB, students can explore reactions and reactors by running realistic simulation experiments. Writing for today's students, Fogler provides instant access to information, avoids extraneous details, and presents novel problems linking theory to practice. Faculty can flexibly define their courses, drawing on updated chapters, problems, and extensive Professional Reference Shelf web content at diverse levels of difficulty. The book thoroughly prepares undergraduates to apply chemical reaction kinetics and physics to the design of chemical reactors. And four advanced chapters address graduate-level topics, including effectiveness factors. To support the field's growing emphasis on chemical reactor safety, each chapter now ends with a practical safety lesson. Updates throughout the book reflect current theory and practice and emphasize safety New discussions of molecular simulations and stochastic modeling Increased emphasis on alternative energy sources such as solar and biofuels Thorough reworking of three chapters on heat effects Full chapters on nonideal reactors, diffusion limitations, and residence time distribution About the Companion Web Site (umich.edu/~elements/6e/index.html) Complete PowerPoint slides for lecture notes for chemical reaction engineering classes Links to additional software, including POLYMATH (TM), MATLAB (TM), Wolfram Mathematica (TM), AspenTech (TM), and COMSOL (TM) Interactive learning resources linked to each chapter, including Learning Objectives, Summary Notes, Web Modules, Interactive Computer Games, Solved Problems, FAQs, additional homework problems, and links to Learncheme Living Example Problems -- unique to this book -- that provide more than 80 interactive simulations, allowing students to explore the examples and ask "what-if" questions Professional Reference Shelf, which includes advanced content on reactors, weighted least squares, experimental planning, laboratory reactors, pharmacokinetics, wire gauze reactors, trickle bed reactors, fluidized bed reactors, CVD boat reactors, detailed explanations of key derivations, and more Problem-solving strategies and insights on creative and critical thinking Register your book for convenient access to downloads, updates, and/or corrections as they become available. See inside book for details.

Compostable Polymer Materials, Second Edition, deals with the environmentally important family of polymers designed to be disposed of in industrial and municipal compost facilities after their useful life. These compostable plastics undergo degradation and leave no visible, distinguishable, or toxic residue. Environmental concerns and legislative measures taken in different regions of the world make composting an increasingly attractive route for the disposal of redundant polymers. This book covers the entire spectrum of preparation, degradation, and evironmental issues related to compostable polymers. It emphasizes recent studies concerning compostability and ecotoxilogical assessment of polymer materials. It descibes the thermal behavior, including flammability properties, of compostable polymers. It also explores possible routes of compostable polymers waste disposal through an ecological lens. Finally, the book examines the economic factors at work, including price evolution over the past decade, the current market, and future perspectives. Compostable Polymer Materials is an essential resource for graduate students and scientists working in chemistry, materials science, ecology, and environmental science.