This clear-sighted volume introduces the concept of "disruptive cooperation"- transformative partnerships between the health and technology sectors to eliminate widespread healthcare problems such as inequities, waste, and inappropriate care. Emphasizing the most pressing issues of a world growing older with long-term chronic illness, it unveils a new framework for personalized, integrative service based in mobile technologies. Coverage analyzes social aspects of illness and health, clinically robust uses of health data, and wireless and wearable applications in intervention, prevention, and health promotion. And case studies from digital health innovators illustrate opportunities for coordinating the service delivery, business, research/science, and policy sectors to promote healthier aging worldwide. Included among the topics: Cooperation in aging services technologies The quantified self, wearables, and the tracking revolution Smart healthy cities: public-private partnerships Beyond silos to data analytics for population health Cooperation for building secure standards for health data Peer-to-peer platforms for physicians in underserved areas: a human rights approach to social media in medicine Disruptive Cooperation in Digital Health will energize digital health and healthcare professionals in both non-profit and for-profit settings. Policymakers and public health professionals with an interest in innovation policy should find it an inspiring ideabook.

This publication is sponsored by the American Association for Medical Systems and Informatics. The Board of AAMSI and the Board of the Society for Computer Medicine, one of AAMSI's predecessors, agreed that a book on application of medical systems and informatics for the practitioner would help promote high quality health care and they charged the Committee on Standards of the Society for Computer Medicine to write such a text. It is intended as a guide for the field of medical systems and informatics with emphasis on standards, terminology, and coding systems. The text, a result of three years of research and effort, has been reviewed by the Board of Directors of AAMSI and approved by the Publications Committee. We believe that you will find it valuable and hope to revise it from time to time to meet current needs. On behalf of the members of the Association, we congratulate the authors and thank them for their efforts. WILLIAM A. BAUMAN, M.D. President American Association for Medical Systems and Informatics Preface This book has been written by the members of the Committee on Standards of the Society for Computer Medicine. We have drawn upon the Society's expertise to prepare an easy-to-read and understandable How-to Do-It text for use by those physicians who are considering computerization of their office in one manner or another."

This two volume set LNBI 10813 and LNBI 10814 constitutes the proceedings of the 6th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2018, held in Granada, Spain, in April 2018.The 88 regular papers presented were carefully reviewed and selected from 273 submissions. The scope of the conference spans the following areas: bioinformatics for healthcare and diseases; bioinformatics tools to integrate omics dataset and address biological question; challenges and advances in measurement and self-parametrization of complex biological systems; computational genomics; computational proteomics; computational systems for modelling biological processes; drug delivery system design aided by mathematical modelling and experiments; generation, management and biological insights from big data; high-throughput bioinformatic tools for medical genomics; next generation sequencing and sequence analysis; interpretable models in biomedicine and bioinformatics; little-big data. Reducing the complexity and facing uncertainty of highly underdetermined phenotype prediction problems; biomedical engineering; biomedical image analysis; biomedical signal analysis; challenges in smart and wearable sensor design for mobile health; and healthcare and diseases.

In this book, leading authors in the field discuss developments of Ambient Assisted Living. The contributions have been chosen and invited at the 8th AAL Congress, Frankfurt/M. The meeting presents new technological developments which support the autonomy and independence of individuals with special needs. The 8th AAL Congress focusses its attention on technical assistance systems and their applications in homecare, health and care.

This book equips students with a thorough understanding of various types of sensors and biosensors that can be used for chemical, biological, and biomedical applications, including but not limited to temperature sensors, strain sensor, light sensors, spectrophotometric sensors, pulse oximeter, optical fiber probes, fluorescence sensors, pH sensor, ion-selective electrodes, piezoelectric sensors, glucose sensors, DNA and immunosensors, lab-on-a-chip biosensors, paper-based lab-on-a-chip biosensors, and microcontroller-based sensors. The author treats the study of biosensors with an applications-based approach, including over 15 extensive, hands-on labs given at the end of each chapter. The material is presented using a building-block approach, beginning with the fundamentals of sensor design and temperature sensors, and ending with more complicated biosensors.New to this second edition are sections on op-amp filters, pulse oximetry, meat quality monitoring, advanced fluorescent dyes, autofluorescence, various fluorescence detection methods, fluoride ion-selective electrode, advanced glucose sensing methods including continuous glucose monitoring, paper-based lab-on-a-chip, etc. A new chapter on nano-biosensors and an appendix on microcontrollers make this textbook ideal for undergraduate engineering students studying biosensors. It can also serve as a hands-on guide for scientists and engineers working in the sensor or biosensor industries.

This work represents an inventive attempt to apply recent advances in nanotechnology to identify and characterise novel polymer systems for drug delivery through the skin. Atomic force microscopy (AFM) measurements of the nanoscale mechanical properties of topical, drug-containing polymeric films enabled the author to identify optimal compositions, in terms of flexibility and substantivity, for application to the skin. To elucidate the enhanced drug release from polyacrylate films incorporating medium chain triglycerides, the author combined AFM studies with the complementary technique of Raman micro-spectroscopy. This experimental strategy revealed that the significant increase in the drug released from these films is the result of a nanoscale two-phase structure. Finally, in experiments examining the microporation of skin using femtosecond laser ablation, the author demonstrated that the threshold at which the skin's barrier function is undermined can be dramatically reduced by the pre-application of ink. The approach allows thermal damage at the pore edge to be minimised, suggesting a very real potential for substantially increasing drug delivery in a minimally invasive fashion.

A Clinical Information System for Oncology describes a medical information system designed and implemented in a cancer center but with broad applicability to medical practice beyond the cancer center environment in both inpatient and outpatient settings. Regarded as forward looking in 1978, the system has the distinction of still being in production. Indeed, its functionality has continued to grow and its technical implementation to evolve with the changing technology over the last decade. The authors detail the functions supported by this unique system, illustrate how it assists in the care process, review its development history, and evaluate its impact on the delivery of care in terms of cost, user satisfaction, and efficacy. Unlike much information technology, the system is an active participant in medical decision making: it includes comprehensive tools for managing and displaying clinical data; automatically produces care plans from protocols; and features unique tools which support the effective use of blood products. Professionals in medical informatics, hospital administrators, and physicians will find this book a valuable addition to their professional library.

This book highlights the interdisciplinary study of cognition, mind and behavior from an information processing perspective, and describes related applications to health informatics. The respective chapters address health problem-solving and education, decision support systems, user-centered interfaces, and the design and use of controlled medical terminologies. Reflecting cutting-edge research on computational methods - including theory, algorithms, numerical simulation, error and uncertainty analysis, and their applications - the book offers a valuable resource for doctoral students and researchers in the fields of Computer Science and Engineering.

This volume presents the proceedings of the 3rd ICBHI which took place in Thessaloniki on 18-21 November, 2017.The area of biomedical and health informatics is exploding at all scales. The developments in the areas of medical devices, eHealth and personalized health as enabling factors for the evolution of precision medicine are quickly developing and demand the development of new scaling tools, integration frameworks and methodologies.

Computational Optical Biomedical Spectroscopy and Imaging covers recent discoveries and research in the field by some of the best inventors and researchers in the world. It also presents useful computational methods and applications used in optical biomedical spectroscopy and imaging. Topics covered include: New trends in immunohistochemical, genome, and metabolomics imaging Computer-aided diagnosis of interstitial lung diseases based on CT image analysis Functional near-infrared spectroscopy and its applications in neurosciences Applications of vibrational spectroscopic imaging in personal care studies Induced optical natural fluorescence spectroscopy for Giardia lamblia cysts Nanoimaging and polarimetric exploratory data analysis Fluorescence bioimaging with applications to chemistry Medical imaging instrumentation and techniques The book also discusses future applications, directions, opportunities, and challenges of optical biomedical spectroscopy and imaging in technical industry, academia, and government. This valuable resource introduces key concepts of computational methods used in optical biomedical spectroscopy and imaging in a manner that is easily understandable to beginners and experts alike.

This book constitutes the refereed proceedings of the 6th International Conference on Health Information Science, HIS 2017, held in Moscow, Russia, in October 2017. The 11 full papers and 7 short papers presented were carefully reviewed and selected from 44 submissions. The papers feature multidisciplinary research results in health information science and systems that support health information management and health service delivery. They relate to all aspects of the conference scope, such as medical/health/biomedicine information resources such as patient medical records, devices and equipments, software and tools to capture, store, retrieve, process, analyze, and optimize the use of information in the health domain; data management, data mining, and knowledge discovery, management of publichealth, examination of standards, privacy and security issues; computer visualization and artificial intelligence for computer aided diagnosis; development of new architectures and applications for health information systems.

This book provides a review of essential research on urinary tract infections (UTIs), as well as a broader perspective on methodologies adopted for the isolation and identification of the bacteria from urine samples of pregnant and non-pregnant women on the basis of their cultural, morphological and biochemical characteristics. The identification is extended to the strain level by means of molecular identification involving BLAST as a bioinformatics tool. The book also addresses the roles of various other bioinformatics tools for tracing the phylogenetic tree and conservation studies among the bacteriocin of the identified bacteria. Lastly, it assesses the antibiotics resistance patterns of these isolates.

This book constitutes the thoroughly refereed post-conference proceedings of the International Conference for Smart Health, ICSH 2017, held in Hong Kong, China,in June 2017.The 18 full papers and 13 short papers presented were carefully reviewed and selectedfrom 38 submissions. They focus on studies on the principles, approaches, models, frameworks, new applications, and effects of using novel information technology to address healthcare problems and improve social welfare.

This book constitutes the refereed joint proceedings of the First International Workshop on Graphs in Biomedical Image Analysis, GRAIL 2017, the 6th International Workshop on Mathematical Foundations of Computational Anatomy, MFCA 2017, and the Third International Workshop on Imaging Genetics, MICGen 2017, held in conjunction with the 20th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2017, in Quebec City, QC, Canada, in September 2017. The 7 full papers presented at GRAIL 2017, the 10 full papers presented at MFCA 2017, and the 5 full papers presented at MICGen 2017 were carefully reviewed and selected. The GRAIL papers cover a wide range of graph based medical image analysis methods and applications, including probabilistic graphical models, neuroimaging using graph representations, machine learning for diagnosis prediction, and shape modeling. The MFCA papers deal with theoretical developments in non-linear image and surface registration in the context of computational anatomy. The MICGen papers cover topics in the field of medical genetics, computational biology and medical imaging.

This book reviews and defines the current state of the art for informatics education in medicine and health care. This field has undergone considerable change as the field of informatics itself has evolved. Twenty years ago almost the only individuals involved in health care who had even heard the term "informatics" were those who identified themselves as medical or nursing informaticians. Today, we have a variety of subfields of informatics including not just medical and nursing informatics, but informatics applied to specific health professions (such as dental or pharmacy informatics), as well as biomedical informatics, bioinformatics and public health informatics. The book addresses the broad range of informatics education programs available today. The Editor and experienced internationally recognized informatics educators who have contributed to this work have made the tacit knowledge explicit and shared some of the lessons they have learned. This book therefore represents the key reference for all involved in the informatics education whether they be trainers or trainees.

This is a meticulously detailed chronological record of significant events in the history of medical informatics and their impact on direct patient care and clinical research, offering a representative sampling of published contributions to the field. The History of Medical Informatics in the United States has been restructured within this new edition, reflecting the transformation medical informatics has undergone in the years since 1990. The systems that were once exclusively institutionally driven - hospital, multihospital, and outpatient information systems - are today joined by systems that are driven by clinical subspecialties, nursing, pathology, clinical laboratory, pharmacy, imaging, and more. At the core is the person - not the clinician, not the institution - whose health all these systems are designed to serve. A group of world-renowned authors have joined forces with Dr Marion Ball to bring Dr Collen's incredible work to press. These recognized leaders in medical informatics, many of whom are recipients of the Morris F. Collen Award in Medical Informatics and were friends of or mentored by Dr Collen, carefully reviewed, editing and updating his draft chapters. This has resulted in the most thorough history of the subject imaginable, and also provides readers with a roadmap for the subject well into later in the century.

Advances in digital technology led to the development of digital x-ray detectors that are currently in wide use for projection radiography, including Computed Radiography (CR) and Digital Radiography (DR). Digital Imaging Systems for Plain Radiography addresses the current technological methods available to medical imaging professionals to ensure the optimization of the radiological process concerning image quality and reduction of patient exposure. Based on extensive research by the authors and reference to the current literature, the book addresses how exposure parameters influence the diagnostic quality in digital systems, what the current acceptable radiation doses are for useful diagnostic images, and at what level the dose could be reduced to maintain an accurate diagnosis. The book is a valuable resource for both students learning the field and for imaging professionals to apply to their own practice while performing radiological examinations with digital systems.

This book brings a comprehensive treatise about obesity, examining the measures that can be taken to stop and even reduce obesity if these right measures are taken in time. Recent studies show that obesity is on the increase at an alarming rate, especially in the industrialized and affluent countries. A number of reasons have been put forward for this increase, including life style choices, over-eating, over-use of commercially processed food, addiction for fast food, high caloric diet specially containing high levels of sugar and fat, lack of exercise and sedentary life style. Also genetic make up has been associated with obesity. Obesity can lead to a variety of lethal diseases, notably coronary heart disease, cancer and diabetes. These diseases account for the highest number of human death amongst all other causes. There are also a number of other side effects associated with obesity including increased stress, loss of intelligentsia, pancreatitis, premature birth and osteoarthritis. In recent years media have been playing important roles in highlighting the lethality and damage caused by obesity, nevertheless no significant effects can be seen in the population and obesity remains on the increase, especially amongst children. The editors believe that it is important that more education, campaign and research are used to stop this increasing disease.

Digital retinal imaging performed by primary care providers and nurses, followed by remote image interpretation (teleretinal imaging), is rapidly acquiring a crucial role in many parts of the world as it permits the detection of major diseases, such as diabetic retinopathy and glaucoma, in patients who would otherwise be beyond the reach of a trained ophthalmologist. In this book, experts from around the world describe how digital teleretinal screening can be set up and optimally utilized. Technical issues are discussed, and the appropriate use of screening for different diseases and in different age groups is explained. The major part of the book draws upon the clinical experience of leading practitioners in a wide range of teleretinal applications. The result is a comprehensive source of high-quality information for clinicians and other health professionals who are involved in eye care delivery, so that they can assess how teleretinal screening might be applied to their working practice.

This is the second edition of a very popular book on DICOM that introduces this complex standard from a very practical point of view. It is aimed at a broad audience of radiologists, clinical administrators, information technologists, medical students, and lecturers. The book provides a gradual, down to earth introduction to DICOM, accompanied by an analysis of the most common problems associated with its implementation. Compared with the first edition, many improvements and additions have been made, based on feedback from readers. Whether you are running a teleradiology project or writing DICOM software, this book will provide you with clear and helpful guidance. It will prepare you for any DICOM projects or problem solving, and assist you in taking full advantage of multifaceted DICOM functionality.

This book constitutes the refereed proceedings of the 8th International Conference on Information Technology in Bio- and Medical Informatics, ITBAM 2017, held in Lyon, France, in August 2017. The 3 revised full papers and 6 poster papers presented were carefully reviewed and selected from 15 submissions. The papers address a broad range of topics in applications of information technology to biomedical engineering and medical informatics.

In this book, a new approach for diagnosis and risk evaluation of ar-terial hypertension is introduced. The new approach was implement-ed as a hybrid intelligent system combining modular neural net-works and fuzzy systems. The different responses of the hybrid system are combined using fuzzy logic. Finally, two genetic algo-rithms are used to perform the optimization of the modular neural networks parameters and fuzzy inference system parameters. The experimental results obtained using the proposed method on real pa-tient data show that when the optimization is used, the results can be better than without optimization. This book is intended to be a refer-ence for scientists and physicians interested in applying soft compu-ting techniques, such as neural networks, fuzzy logic and genetic algorithms, in medical diagnosis, but also in general to classification and pattern recognition and similar problems.

This book presents research on emerging computational intelligence techniques and tools, with a particular focus on new trends and applications in health care. Healthcare is a multi-faceted domain, which incorporates advanced decision-making, remote monitoring, healthcare logistics, operational excellence and modern information systems. In recent years, the use of computational intelligence methods to address the scale and the complexity of the problems in healthcare has been investigated. This book discusses various computational intelligence methods that are implemented in applications in different areas of healthcare. It includes contributions by practitioners, technology developers and solution providers.

This book constitutes the thoroughly refereed post-conference proceedings of the Third International Workshop on Computer Assisted and Robotic Endoscopy, CARE 2016, held in conjunction with MICCAI 2016, in Athens, Greece, in October 2016. The 11 revised full papers were carefully selected out of 13 initial submissions. The papers are organized on topical secttion such as computer vision, graphics, robotics, medical imaging, external tracking systems, medical device controls systems, information processing techniques, endoscopy planning and simulation.

Teledentistry is of growing interest to the healthcare world. Over the last few years, momentum is growing in research and service in Teledentistry - mostly carried out by tertiary medical institutes across the world. While Teledentistry is advanced in some sub-specialties, it has high potential to receive more attention from general communities, dentists, dental hygienists, physicians, nurses, researchers and students. For the first time, this book will present essential knowledge from experts in this field. They will discuss the current status of technology and service in various Telledentistry sub specialties and its future implications. Written by experts from around the globe, (i.e., from USA, Europe, Australia and Asia), this book presents technical issues and clinical applications. It includes collective experiences from dental service providers in different parts of the world practicing a wide range of Teledentistry applications. This book lays the foundations for the globalization of Teledentistry procedures, making it possible for dental service to be delivered anywhere in the world.