Over the next few years, the Connecting for Health IT programme for the NHS in England is due to implement electronic prescribing systems at all hospitals in England. Furthermore, the other UK countries are likely to follow suit with clinical IT implementation programmes, and these developments will generate interest in electronic prescribing at European and international level. There is therefore likely to be an exponential growth in the significance of electronic prescribing over the next ten years. Principles of Electronic Prescribing discusses the basic principles of design and implementation of secondary care electronic medicines management systems, and how their design and configuration can impact on benefits realization, hospital workflow and clinical practice.

This book provides a broad overview of the topic Bioinformatics with focus on data, information and knowledge. From data acquisition and storage to visualization, ranging through privacy, regulatory and other practical and theoretical topics, the author touches several fundamental aspects of the innovative interface between Medical and Technology domains that is Biomedical Informatics. Each chapter starts by providing a useful inventory of definitions and commonly used acronyms for each topic and throughout the text, the reader finds several real-world examples, methodologies and ideas that complement the technical and theoretical background. This new edition includes new sections at the end of each chapter, called "future outlook and research avenues," providing pointers to future challenges. At the beginning of each chapter a new section called "key problems", has been added, where the author discusses possible traps and unsolvable or major problems.

This book constitutes the thoroughly refereed post-conference proceedings of the Third International Symposium on Foundations of Health Information Engineering and Systems, FHIES 2013, held in Macau, China, in August 2013. The 19 revised full papers presented together with 1 invited talk in this volume were carefully reviewed and selected from 22 submissions. The papers are organized in following subjects: panel position statements, pathways, generation and certification, interoperability, patient safety, device safety, formal methods and HIV/AIDS and privacy.

The rate at which toxicological data is generated is continually becoming more rapid and the volume of data generated is growing dramatically. This is due in part to advances in software solutions and cheminformatics approaches which increase the availability of open data from chemical, biological and toxicological and high throughput screening resources. However, the amplified pace and capacity of data generation achieved by these novel techniques presents challenges for organising and analysing data output. Big Data in Predictive Toxicology discusses these challenges as well as the opportunities of new techniques encountered in data science. It addresses the nature of toxicological big data, their storage, analysis and interpretation. It also details how these data can be applied in toxicity prediction, modelling and risk assessment. This title is of particular relevance to researchers and postgraduates working and studying in the fields of computational methods, applied and physical chemistry, cheminformatics, biological sciences, predictive toxicology and safety and hazard assessment.

The three-volume set LNCS 8149, 8150, and 8151 constitutes the refereed proceedings of the 16th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2013, held in Nagoya, Japan, in September 2013. Based on rigorous peer reviews, the program committee carefully selected 262 revised papers from 789 submissions for presentation in three volumes. The 81 papers included in the third volume have been organized in the following topical sections: image reconstruction and motion modeling; machine learning in medical image computing; imaging, reconstruction, and enhancement; segmentation; physiological modeling, simulation, and planning; intraoperative guidance and robotics; microscope, optical imaging, and histology; diffusion MRI; brain segmentation and atlases; and functional MRI and neuroscience applications.

Providing genome-informed personalized treatment is a goal of modern medicine. Identifying new translational targets in nucleic acid characterizations is an important step toward that goal. The information tsunami produced by such genome-scale investigations is stimulating parallel developments in statistical methodology and inference, analytical frameworks, and computational tools. Within the context of genomic medicine and with a strong focus on cancer research, this book describes the integration of high-throughput bioinformatics data from multiple platforms to inform our understanding of the functional consequences of genomic alterations. This includes rigorous and scalable methods for simultaneously handling diverse data types such as gene expression array, miRNA, copy number, methylation, and next-generation sequencing data. This material is written for statisticians who are interested in modeling and analyzing high-throughput data. Chapters by experts in the field offer a thorough introduction to the biological and technical principles behind multiplatform high-throughput experimentation.

AIDS is the fourth leading cause of death among women of childbearing age and is increasing by about 8% a year in this group. * And yet, our understanding of the impact of HIV and AIDS on women's lives remains fragmented and incomplete. After a decade of struggling with mounting surveys of risk behavior, clinical trials, and behavioral interventions that were based primarily on experience with gay communities in large cities and, subsequently, on the needs of injection drug users, we have not given programs for women the attention they require if they are to be meaningful, effective, and gender appropriate. This book will introduce the reader to the range of complex issues of HIV and AIDS in women's lives. Ann O'Leary and Loretta Sweet Jemmott have assembled an impres sive list of authors who have contributed chapters from different disciplinary viewpoints. The reader will find information on prevention programs that have been effective for adolescent girls, on culturally specific strategies for African American and Latina women, and on the multiple issues of sub stance use and HIV that need to be faced by any outreach and intervention programs for drug-using women.

The current book presents select proceedings from the Eleventh Annual Conference of AASMI (The American Association for the Study of Mental Imagery) in Washington, DC, 1989, and from the Twelfth Annual Conference of AASMI in Lowell and Boston, MA, 1990. This presentation of keynote addresses, research papers, and clinical workshops reflects a broad range of theoretical positions and a diverse repertoire of methodological approaches. Within this breadth and diversity, however, four aspects of the nature of imagery stand out: its mental nature, its private nature, its conscious nature, and its symbolic nature. The mental nature of imagery--i.e., its epistemological aspect--is explored in the book's first section of articles by Marcia Johnson, Laura Snodgrass, Leonard Giambra and Alicia Grodsky, Vija Lusebrink, Selina Kassels, Helane Rosenberg and Yakov Epstein, M. Elizabeth D'Zamko and Lynne Schwab, and Laurence Martel. These first eight articles fall, essentially, into various domains of cognitive psychology, including the psychology of art and educational psychology. In the second section, the private nature of imagery is studied by Ernest Hartmann, Nicholas Spanos, Benjamin Wallace, Deirdre Barrett, John Connolly, James Honeycutt, Dominique Gendrin, and James Honeycutt and J. Michael Gotcher. These studies, which fall within the realm of personality and social psychology, bring to light the fact that many very public interpersonal behaviors reflect very private images. Such behaviors range from interpersonal rapport with a hypnotist, to rapport with a forensic jury.

This text provides a foundation for the initiation of advocacy efforts and for the evaluation of their success and includes topics such as: specific strategies, grassroots advocacy efforts, formation and development of coalitions, advocacy efforts in legislatures, administrative agencies, court, and the media. It is of interest to public and urban health workers, social workers, community organizers, and legislators.

Responding to demographic changes among physicians and six years of new experiences since the first edition, Dr. Myers has revamped his well received work. He includes new information on older physicians, gay and lesbian physicians, medical student abuse, economic strain on interns, depression, malpractice, ethical violations, and other stressors which may cause marital difficulties. Therapists seeking to council symptomatic physicians, as well physicians themselves, will find this a humane, readable, and useful book.

This volume is for students and practitioners interested in improving their understanding and skills in the area of needs assessment. The text follows the typical sequence of an actual needs assessment process. Case studies are used to illustrate conceptualization of the task through the application of needs-based data to effective public health solutions. Examples are drawn from myriad public health efforts, recognizing that not all public health sector agencies bear direct responsibility for all activities that could be considered part of public health.

The field of health psychology has grown dramatically in the last decade, with exciting new developments in the study of how psychological and psychosocial processes contribute to risk for and disease sequelae for a variety of medical problems. In addition, the quality and effectiveness of many of our treatments, and health promotion and disease prevention efforts, have been significantly enhanced by the contributions of health psychologists (Taylor, 1995). Unfortunately, however, much of the theo rizing in health psychology and the empirical research that derives from it continue to reflect the mainstream bias of psychology and medicine, both of which have a primary focus on white, heterosexual, middle-class American men. This bias pervades our thinking despite the demographic heterogeneity of American society (U. S. Bureau of the Census, 1992) and the substantial body of epidemiologic evidence that indicates significant group differences in health status, burden of morbidity and mortality, life expectancy, quality of life, and the risk and protective factors that con tribute to these differences in health outcomes (National Center for Health Statistics, 1994; Myers, Kagawa-Singer, Kumanyika, Lex, & M- kides, 1995). There is also substantial evidence that many of the health promotion and disease prevention efforts that have proven effective with more affluent, educated whites, on whom they were developed, may not yield comparable results when used with populations that differ by eth nicity, social class, gender, or sexual orientation (Cochran & Mays, 1991; Castro, Coe, Gutierres, & Saenz, this volume; Chesney & Nealey, this volume).

Following both a patient and an employee through a physician visit, this is a "how-to" manual for implementing practice management solutions. The first section provides information and examples prior to the patient visit, and includes examples of physicians who utilize email and Web sites to attract patients, electronic scheduling systems to decrease wait time, and registration systems which can verify insurance information. The second section focuses on electronic medical records, electronic referral systems, billing and collection systems, and follow-up patient education and discharge information, thus portraying the "future physician office visit." The third section centres on the physician practice manager's daily operations and how technology can achieve efficacy.

Information technology constantly changes and quickly becomes obsolete. The methodology of planning and implementing a health care information system, however, is more constant. Through practical, step-by-step guidelines, the author demonstrates how to establish the strategy and architecture against which vendor and system decisions must be made. Both management and technical perspectives are discussed. Thus, regardless of the technology used, the health care administrator and systems manager learn to implement information systems successfully and to link those systems with business strategy to achieve higher quality and more cost-effective patient care.

Many of the changes occurring within medicine are being catalyzed by the proliferation of professional and social activity with the internet and mobile technology. Understanding of the way in which healthcare is being transformed by IT is key in the improvement of medical standards and reduction of cost. This book presents the current and future trends in the transformation of healthcare services in the Information Society Era.

The synergy between computer technology and medical services has opened fascinating new possibilities for benefit in areas such as continuing care, chronic disease treatment and old people home monitoring, bringing with it the promise of essential changes in existing models of care delivery and system performance. This book addresses the priorities within international informatics and presents a complete and thorough survey of the most promising e-health technologies. This is illustrated with the inclusion of case reports indentifying real applications of the techniques, with the focus on providing an integrated overview of e-health, and the medical, sociological and technical aspects.

The authors primary objective has been to provide an in-depth study of internet-enhanced healthcare services, while mobile technology is also reviewed in the context of modern wireless technologies. The authors have provided a unique analysis of the evolution of healthcare services. The book is illustrated by numerous examples and comes together to provide a valuable set of tele-care solutions available to modern informatics practice."

Performance Improvement through Information Management highlights performance improvement and business strategies throughout various health care settings, focusing on business drivers and management mechanisms, explaining when, how, and why information technology solutions are of value. Structured on three levels: Market Environment, Transformational Processes, and Enabling Technologies, the text describes the current state of the art of health care and the shape of things to come, and provides practical solutions and strategies for implementing applications of technology within the current context of health care and its transformation. This text will be an invaluable reference to the chief executive officers, chief information officers, senior executives, and board members who are shaping health care today and into the 21st century. Likewise, it will appeal to healthcare administrators and managers, healthcare systems specialists, and students in advanced healthcare professional and academic programs.

In this volume, Steven Evans reports on a quarter century of work-work that resulted in a commercial product known as the PACE System. An advanced clinical management system, PACE links all care delivery set tings and reaches across multiple episodes. It offers capabilities critical to managed care, including care planning and clinical pathways, the critical pathway analyzer and clinical repository central to outcomes-based care, and more. The pages that follow describe the PACE project, focusing on its knowl edge base and semantic network. They offer insights into system implemen tation and address the synthesis of principles within the PACE System. From this project in nursing informatics, Steven Evans relates both suc cesses and failures, sharing the strategies and techniques to adopt and pitfalls to avoid in a project that followed five years of preliminary theo retical work. With clarity and candor, he gives us the benefit of two decades of project development, first in academia and then in the commercial sector. Over the course of the project, many tens of millions of dollars and close to 500 person-years of effort were invested. Building on the strong conceptual base developed at Creigton University's School of Nursing, the project has seen exponential growth in its clinical capabilities since entering the commercial sector in 1989.

Fundamentals of Clinical Practice is an introductory textbook focusing on the patient physician relationship. Formerly closeted behind closed doors, this most intimate of healing relationships is coming under increasing scientific scrutiny. Physicians and other healthcare providers are beginning to understand the critical importance of this relation ship to the health of patients, as well as to larger societal relationships, systems, and values. To facilitate the reader's exploration of the patient-physician relationship, all chap ters include numerous illustrative cases and conclude with cases for discussion that allow small groups of learners to tackle these difficult issues. Our hypothesis is that through discussion a deeper understanding of the dynamics of the patient-physician relationship will allow medical students and other future healthcare providers to form more effective therapeutic relationships with their patients. Part I of this textbook, "The Patient," explores the relationship through the patient's perspective, with chapters on human health and disease and individual and family devel opment. Understanding the patient's perspective is critical to establishing a sound thera peutic relationship. The day when a physician could maintain solely a disease or techno logical perspective is fading fast under the weight of patient criticism, particularly in primary care fields. Patients judge such a disease or technological perspective as less humane and frequently vote with their feet, finding other physicians who are much better able to balance the caring aspects of medicine with the curing.

This book has been a long time in the making. The computerization activi ties described in these pages began in 1977 at the Department of Veterans Affairs (VA), but we devoted most of our focus and efforts to building and then implementing the extensive hospital information system known as the Decentralized Hospital Computer System (DHCP) throughout VA. Deliv ering the product has been our primary goal. We spent relatively little time documenting or describing our experiences or lessons learned. Except for some presentations at national meetings and a relatively few publications, almost none of which were in the standard trade journals read by Chief Information Officers (CIOs) and equivalent top managers in the private and nonprofit sectors, VA's accomplishments remained a well-kept secret. In 1988, Helly Orthner encouraged VA staff to consider writing a book, but the press of day-to-day activities always seemed to take precedence, and the book languished on the back burner."

Introduction to Clinical Informatics fills a void in the Computer in Health Care series. With this volume, Patrice Degoulet and Marius Fieschi provide a comprehensive view of medical informatics and carry that concept forward into the realm of clinical informatics. The authors draw upon their experi ences as medical school faculty members in France, where informatics has long been integrated into the curriculum and where the French version of this very book has been used, tested, and revised. In intent and content, this volume stands as the companion volume to Introduction to Nursing Informatics, one of the series' best selling titles. For practitioners and students of medicine, pharmacy, and other health profes sions, Introduction to Clinical Informatics offers an essential understanding how computing can support patient care, clarifying practical uses and critical issues. Today medical schools in the United States are making informatics a part of their curriculum, with required medical informatics blocks at the onset of training serving as the base for problem-based learning throughout the course of study. In an increasingly networked and computerized environ ment, health-care providers are having to alter how they practice. Whether in the office, the clinic, or the hospital, health-care professionals have access to a growing array of capabilities and tools as they deliver care. Learning to use these becomes a top priority, and this volume becomes a valuable resource.

Information and the technology to rapidly transmit, analyze, document, and disperse this information are increasing arithmetically, if not logarithmi cally. Arguably, no discipline better exemplifies this trend than medicine. It can be further argued that care of the trauma patient is one of the better examples of informatics and the potential benefit to the health profession als who care for these patients. Maull and Augenstein have provided us with a primer on informatics and its use in trauma care. The subject matter is timely and covers the gamut of trauma care from prehospital to rehabilitation. Who will benefit from trauma informatics? A simple answer would be anyone who takes care of trauma patients. From a broader perspective, however, at least three examples illustrate how trauma informatics can be used today to exert a positive effect on patient outcome. The first example is care of combat casualties, including battlefield resuscitation, evacuation, acute care, and ultimate return to the continental United States. Current technology is such that via global positioning satellite, a corpsman could transmit to a remote area the vital signs and pertinent physical findings of a combat casualty. Furthermore, the location of the corpsman and the casu alty would be precisely known, and consultation and destination disposition would be possible. The injured person, when admitted to a combat support hospital, could be continuously monitored and additional remote consulta tion obtained.

For two decades, I have been responding to questions about the nature of health psychology and how it differs from medical psychology, behavioral medicine, and clinical psychology. From the beginning, I have taken the position that any applica tion of psychological theory or practice to problems and issues of the health system is health psychology. I have repeatedly used an analogy to Newell and Simon's "General Problem Solver" program of the late 1950s and early 1960s, which had two major functional parts, in addition to the "executive" component. One was the "problem-solving core" (the procedural competence); the other was the representa tion of the "problem environment. " In the analogy, the concepts, knowledge, and techniques of psychology constitute the core competence; the health system in all its complexity is the problem environment. A health psychologist is one whose basic competence in psychology is augmented by a working knowledge of some aspect of the health system. Quite apparently, there are functionally distinct aspects of health psychology to the degree that there are meaningful subdivisions in psychological competence and significantly different microenvironments within the health system. I hesitate to refer to them as areas of specialization, as the man who gave health psychology its formal definition, Joseph Matarazzo, has said that there are no specialties in psychology (cited in the editors' preface to this book)."

This open access book comprehensively covers the fundamentals of clinical data science, focusing on data collection, modelling and clinical applications. Topics covered in the first section on data collection include: data sources, data at scale (big data), data stewardship (FAIR data) and related privacy concerns. Aspects of predictive modelling using techniques such as classification, regression or clustering, and prediction model validation will be covered in the second section. The third section covers aspects of (mobile) clinical decision support systems, operational excellence and value-based healthcare. Fundamentals of Clinical Data Science is an essential resource for healthcare professionals and IT consultants intending to develop and refine their skills in personalized medicine, using solutions based on large datasets from electronic health records or telemonitoring programmes. The book's promise is "no math, no code"and will explain the topics in a style that is optimized for a healthcare audience.

This volume presents the contributions of the third International Conference on Advancements of Medicine and Health Care through Technology (Meditech 2011), held in in Cluj-Napoca, Romania.
The papers of this Proceedings volume present new developments in
- Health Care Technology,
- Medical Devices, Measurement and Instrumentation,
- Medical Imaging, Image and Signal Processing,
- Modeling and Simulation,
- Molecular Bioengineering,
- Biomechanics.