Despite the rising popularity of the minimally invasive laparoscopic option, open nephron-sparing surgery is still seen by many experts as the 'gold standard' for open surgery for kidney tumors and should remain the first choice for many patients. This challenges the idea that less-invasive therapies are always more desirable than open surgery. While laparoscopic nephron-sparing surgery may be a more attractive option for treating small, easily accessible kidney tumors, for large tumors this is not always the case. Nephron-sparing surgery is a outstanding text that analyses all forms of surgery, open or laparoscopic, as well as providing a backdrop on renal cell carcinoma in general, and the complications and outcomes following surgery that both surgeon and patient will face. Featuring 100 colour photos, the text includes chapters on: Imaging renal masses: current status Open nephron-sparing surgery for renal cell carcinoma Minimally invasive approaches for renal cell carcinoma: an overview Laparoscopic partial nephrectomy Controversies in nephron-sparing surgery Renal cell carcinoma: long-term outcome following nephron-sparing surgery Dr Sasidharan and Professor Soloway have created a superb text covering all aspects of nephron-sparing surgery that should provide excellent guidance for all those who are just beginning to perform nephron-sparing surgery or act as an aide-memoire for those familiar with nephron-sparing surgery.

The last few years have seen major advances in all aspects of the understanding and treatment of kidney cancer, particularly the commonest variant clear cell carcinoma of the kidney. This book brings the reader up to date with these developments, covering aetiology, epidemiology, pathogenesis, prognostic factors, presentation, interventional radiology, minimally invasive surgery, surgery for locally advanced tumours and for metasatic disease, adjuvant medical therapies, therapies for advanced disease, radiotherapy and palliation of symptoms. Each chapter is written by acknowledged experts in the field. The reader gains an excellent idea of the state of the art in the treatment of kidney cancer in an accessible format.

The Systems of the Body series has established itself as a highly valuable resource for medical and other health science students following today's systems-based courses. Now thoroughly revised and updated in this third edition, each volume presents the core knowledge of basic science and clinical conditions that medical students need, providing a concise, fully integrated view of each major body system that can be hard to find in more traditionally arranged textbooks or other resources. Multiple case studies help relate key principles to current practice, with links to clinical skills, clinical investigation and therapeutics made clear throughout. Each (print) volume also now comes with access to the complete, enhanced eBook version, offering easy anytime, anywhere access - as well as self-assessment material to check your understanding and aid exam preparation. The Renal System provides highly accessible coverage of the core basic science principles in the context of clinical case histories, giving the reader a fully integrated understanding of the system and its major diseases. Introduction to the Renal System Body Fluids, Nephron Function and Diuretics Water Balance and Regulation of Osmolality Acid-Base Balance and Regulation of pH Glomerular Filtration and Acute Kidney Injury Proteinuria and the Nephrotic Syndrome Glomerulonephritis and the Acute Nephritic Syndrome Diabetic Nephropathy and Chronic Kidney Disease Kidney Failure and Replacement of Renal Function Hypertension and the Kidney Pregnancy and the Kidney Urinary Tract Obstruction and Stones Renal Masses, Cysts and Urinary Tract Tumours Drugs and the Kidney Systems of the Body Series: The Renal System The Musculoskeletal System The Nervous System The Digestive System The Endocrine System The Respiratory System The Cardiovascular System

Formulated by members of the International Scientific Committee of Radionuclides in Nephro-urology (ISCORN), Functional Imaging in Nephro-urology is not a textbook on uronephrology or radionuclides in nephro-urology, or even a book on new techniques in imaging. What the editor and authors provide here is a unique opportunity to evaluate the strategic management techniques (both diagnosis and follow-up) of a number of uronephrological entities.
Demonstrating the experience of the authors in using various imaging modalities, and detailing the benefits and controversies which are associated with their clinical applications, this text presents management strategies based on the patient, the choice of modality, and cost implications.
Detailed, well-referenced and highly illustrated, this is an important book for radiologists, nephrologists and urologists working with children and adults, specialists in renal nuclear medicine, and pediatricians.

A much-needed, up-to-date guide to the clinical management of kidney disorders in children and adolescents, this text presents the essentials of diagnosis and treatment in this important field, with an indication of when referral to, or consultation with, the pediatric nephrologist is needed.

With a team of international contributors who have had a significant global impact on the development of pediatric nephrology, this user-friendly resource takes the findings of specialists to a much wider audience in training and in primary care.

With detailed contributions and research from experts, this reference supplies an abundance of information on acid-base physiology, disorders of acid-base equilibrium, and the management and treatment of these disorders in clinical practice. A unique and timely resource, this guide provides a large number of tables, references, and figures to illustrate the relationship between the underlying physiology and diagnosis of acid-base disorders. Reviewing current information on the pathophysiology of acid-base disorders from both a molecular and integrative perspective, the book provides straightforward guidelines for the diagnosis and management of disturbances of acid-base homeostasis.

This book provides a current understanding of Continuous Renal Replacement Therapies (CRRT) techniques with a focus on drug dosing in critically ill children receiving CRRT. Strategies include the role of therapeutic drug monitoring, effect of CRRT on drug pharmacokinetics, variations in the drugs properties, newer kidney injury biomarkers and simple and easy methods for estimating drug clearance. The conclusion of this book features case reports focused on the patients' symptoms and laboratory data as they present in clinical practice and the type of CRRT modality needed to provide quality, safety, and cost-effectiveness of patient care. Pediatric Continuous Renal Replacement Therapy will expand the clinical knowledge and experience of practicing nephrologists and other professionals involved in the care of children suffering from Acute Kidney Injury (AKI) to improve and sustain their quality of life.

Concise, thorough, and easy to use, Handbook of Nephrology and Hypertension 7th Edition, provides authoritative guidance on diagnosing and treating patients with a wide range of kidney disorders and hypertension, including coverage of dialysis and transplantation. Lead editor Dr. Christopher Wilcox and his team of section editors Drs. Michael Choi, Limeng Chen, Winfred N. Williams, and Mark S. Segal oversee a group of expert authors, both faculty and fellows, who focus on common problems and challenges in this complex field. Brief, focused chapters contain abundant figures and algorithms and have been updated to reflect new findings in renal cystic diseases, new drugs used for hypertension, transplantation and renal protection, and much more. Includes new chapters on Urinalysis and Hematuria, Hypertensive Nephropathy, Drug Use in Kidney Disease, Resistant and Secondary Forms of Hypertension, and Medical Reimbursement and Economics of Nephrology Practice Contains dedicated chapters on drugs for edema, hypertension, and glomerulonephritis, as well as drugs pertaining to renal transplant, covering how to select and use drugs, doses, and adverse effects, and how prescribing should be altered in patients with renal insufficiency Features a new four-color design and more figures and algorithms throughout Shares the experience and knowledge of distinguished international authors from top universities in both the U.S. and China, with many chapters co-authored by a faculty and a fellow Enrich Your eBook Reading Experience Read directly on your preferred device(s),such as computer, tablet, or smartphone. Easily convert to audiobook,powering your content with natural language text-to-speech.

For more than 30 years, the highly regarded Secrets Series (R) has provided students and practitioners in all areas of health care with concise, focused, and engaging resources for quick reference and exam review. Nephrology Secrets, 4th Edition, features the Secrets' popular question-and-answer format that also includes lists, tables, and an easy-to-read style - making reference and review quick, easy, and enjoyable. The proven Secrets (R) format gives you the most return for your time - concise, easy to read, engaging, and highly effective. Covers the full range of essential topics in nephrology for in-training or practicing professionals. Written and fully updated by global experts and thought leaders in nephrology. Top 100 Secrets and Key Points boxes provide a fast overview of the secrets you must know for success in practice and on exams. Portable size makes it easy to carry with you for quick reference or review anywhere, anytime. New chapters on home dialysis, onco-nephrology, and palliative care nephrology. Fully updated throughout, with clear illustrations, figures, and flow diagrams that expedite study and review. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.

This book details protocols on classical methods and very modern ex vivo mammalian developmental kidney model systems. Chapters focus on generation of mosaic embryonic kidneys, culture of the kidney tissues ex vivo, embryonic kidney progenitor cell, 3Dkidney model cell line based cultures, programming the kidney cell fates in human pluripotent cells, protocols to target the functional players in kidney ontogenesis, 4D and 3D ex vivo imaging, drosphila, and computational approaches to kidney ontogenesis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Kidney Organogenesis: Methods and Protocols aims to ensure successful results in the further study of this vital field.

The need for adequate means by which to improve urine output is very old. Even in the "Scuola Salernitana," the oldest medieval medical school in Western Europe, about 1000 years ago it was taught how to improve urine output. The list of known "diuretica" included herbs, plants, roots, vegetables, in particular asparagus, fennel and carrot. The first diuretic drugs, however, were mercurial compounds. Thus, calomel, mercurous chloride, was initially used as a diuretic in the sixteenth century by Paracelsus, being one of the ingredients of the so-called "Guy's Hospital pill." But calomel had a cathartic effect so that it was replaced by organic mercurial compounds. These diuretics were clearly toxic. After the discovery of the car bonic anhydrase, in the early 1930s, and the introduction of sulfanilamide as a chemotherapeutic agent, it was observed that this drug was inhibiting carbonic anhydrase in vitro and urinary acidification in vivo thereby causing metabolic acidosis; urine output, however, appeared to increase. Subsequent studies led to the synthesis of more potent analogs, in particular acetazolamide. Studies on car bonic anhydrase inhibitors led to the synthesis of benzothiadiazides which disclosed much less inactivating action on carbonic anhydrase and much more diuretic effect through an inhibition of tubular transport of sodium and chloride. Chlorothiazide was the first member of this class of diuretics. Thiazides are still used in clinical practice."

"This informative book has been put together with the support and input of many clinical renal experts, who have been willing to share their knowledge and years of experience and I'm sure it will be an excellent resource for those caring for kidney patients for the first time -- as well as for those with some years of experience " - From the Foreword by Rosemary Macri, Chief Executive of the British Kidney Patient Association Kidney Disease Management: A Practical Approach for Non-Specialists has been written to help optimise the care of people with chronic kidney disease (CKD) across the healthcare spectrum. It is aimed at a range of professionals, including nurses, junior doctors, general practitioners, pharmacists and dieticians. Specialists in training may also find it useful. It highlights the practical considerations necessary to care for people with kidney problems in situations where a specialist practitioner is not always required or immediately available. This book explores: Policy context and CKD; overview of CKD and management; managing CKD in primary care; treatment modalities in CKD; psychosocial aspects of living with CKD, Acute kidney Injury in hospitalised patients; surgery and kidney injury; medication management in CKD; nutrition and CKD; support and palliative care for people with CKD. Key features: - Based on best practice and written in an accessible format aimed at busy practitioners - Emphasises the centrality of the patient and family and the need to share information and expertise across traditional boundaries - Written by professionals renowned in their field, both generalists and specialists, who have extensive experience of the practicalities of managing complex patients.