Psychosocial Aspects of Chronic Kidney Disease: Exploring the Impact of CKD, Dialysis, and Transplantation on Patients provides an overview of the emotional and psychological challenges faced by people with renal disease. This book outlines the epidemiology and treatment of the psychosocial factors affecting them. The sections in the book cover psychiatric illness in the earlier and middle stages of chronic kidney disease, end-stage renal disease treated with dialysis, and renal transplantation. The book concludes with a section on special considerations, delving into topics such as treating children and adolescents, quality of life, caregiver burden, challenges in psychosocial research in kidney disease, and future directions for intervention.

More than 400,000 people in the United States undergo kidney dialysis. For many, the prospect of a regular appointment with a dialysis machine seems like the end of life itself. But that reaction couldn't be more wrong.
In Dialysis Without Fear, psychiatrist and dialysis patient Dr. Daniel Offer joins with his wife, Marjorie Kaiz Offer, and daughter, Susan Offer Szafir, to reveal how life can be lived--and lived well--on dialysis. Drawing on his long career as a medical expert and more than seven years of
experience as a patient, Dr. Offer convincingly dispels the misconceptions surrounding this treatment, revealing how most dialysis patients can travel, work, and continue to partake in life's joys and celebrations. But the fears and hardships can be quite real, and Dr. Offer brings his years as a
psychiatrist to bear as he provides practical advice on how patients can overcome them. He walks the reader through each step of dialysis, explains different types of treatment, examines the pros and cons of a transplant, and discusses side effects. Dialysis, he notes, affects the entire family; his
own wife and daughter provide realistic insights into how relatives can cope and thrive together. Along the way, they provide a treasure trove of tips on adapting to the new diet, traveling overseas, and adjusting working hours. The Offers also relate inspiring success stories, sharing the humor,
courage, and triumphs of real families.
Life on dialysis is unquestionably difficult--but the difficulties can be overcome. With this inspiring, practical guide, patients can learn to live without fear, fulfill their hopes, and enjoy every day.

This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in diabetes, kidney and wound treatment. All chapters are contributed by pre-eminent scientists in the field and covers such topics as stem cells and cell therapy in the treatment of diabetes mellitus, kidney failure, wound and other skin aging diseases, characteristics of some kinds of stem/progenitor cells for therapy, future directions of the discussed therapies and much more. Pancreas, Kidney and Skin Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.

Kidney Development, Disease, Repair and Regeneration focuses on the molecular and cellular basis of kidney development, exploring the origins of kidney lineages, the development of kidney tissue subcompartments, as well as the genetic and environmental regulation of kidney development. Special coverage is given to kidney stem cells and possible steps towards kidney repair and regeneration. Emphasis is placed on the fetal origins of postnatal renal disease and our current understanding of the molecular basis of damage and repair. Biomedical researchers across experimental nephrology and developmental biology will find this a key reference for learning how the underlying developmental mechanisms of the kidney will lead to greater advances in regenerative medicine within nephrology.

Dr. John Kellum has assembled an essential update on the topic of Nephrology as it relates to Critical Care Medicine. Articles include: Diagnostic criteria, Biomarkers for AKI, Sepsis-induced AKI,Drug-induced AKI, Cardio-renal syndrome,Surgery Associated AKI,Contrast-induced AKI, Principles of Fluid Therapy,Fluid composition and clinical effects, Renal replacement therapy, and Understanding acid-base.

Welcome.- Elliott F. Osserman In Memoriam.- The 1990 Guidelines for Nomenclature and Classification of Amyloid and Amyloidosis.- I Protein Aa/Saa and Secondary Amyloidosis.- The Human Saa Genes and Their Regulation by Cytokines.- Genetic Isofocusing Variant of Human Serum Amyloid A.- Sequence Analysis of a Third Human Saa Gene.- Human Serum Amyloid-A Protein: Variability Demonstrated by Cdna Sequencing and Expression Studies.- Abyssinian Cat Model of Aa Amyloidosis: Saa Gene Analysis.- Mink Serum Amyloid a Protein - Expression and Primary Structure of Amyloidogenic and Non-Amyloidogenic Isotypes.- Primary Structure of Two Rabbit Serum Amyloid a Proteins (Saa) Based on Cdna Sequence.- Biosynthesis and Processing of Saa by Mouse L-Cells Transfected with the Human Saag9 Gene.- Regulation of Serum Amyloid a (Saa) Synthesis in Hep 3B Cells by Cytokines and Corticosteroids.- Regulation of Saa Synthesis by Cytokines in a Human Hepatoma Cell Line.- Saa Secretion from Cytokine-Stimulated Human Hepatoma Cells Requires Hdl.- Interferon a Induces Tnf Elevations in Vivo. Correlation with Other Acute Phase React Ants.- Acute Phase Protein, Serum Amyloid a, Inhibits Il-1- and Tnf-Induced Fever and Hypothalamic Pge2 In Mice.- Human Recombinant TNF-? and Poly I. Poly C Induce Saa and Enhance Amyloidosis in Hamster.- The Physiology of the Acute Phase Serum Amyloid a (Saa) Response in Mice.- Mouse Saa3: Detection in Mouse Tissues with Specific Antibody.- Generation and Use of Site-Specific Antibodies Against Saa.- The N-Terminus is the Lipid-Binding Site of Saa: Supporting Evidence by Moabs.- Epitope Mapping of Amyloid-a Protein Using Monoclonal Antibodies.- Reactive (Aa) Amyloidosis in a 14 Year Old with No Predisposing Disease.- Induction of Amyloidosis in Mice: Preparation of Active Azocasein (Azo) and Effect of Endotoxin (Lps).- Serum Amyloid a (SAA) Induction in the Serum High Density Lipoproteins of the Syrian Hamster.- The Complete Primary Structure of Bovine Serum Amyloid Protein a (SAA) and of Tissue Amyloid Fibril Protein a (AA) Subspecies.- Degradation of Saa in Amyloid Fibrils by Elastase.- Evolutionary Aspects of Protein Saa.- Strain Specific Variation in Expression of Novel Mouse Apo-Saa Isoforms.- Saa Isotypes in Patients with Secondary Amyloidosis.- Differential Regulation of Human Serum Amyloid a Isoforms.- The Effect of SAA-Derived Fragment - SAA2-82 - On Platelet Aggregation.- Serum Amyloid a, An Acute Phase Protein, Inhibits Platelet Activation.- Serum Amyloid a (SAA)-Related Peptide Isolated from Synovial Fluid Modulates Superoxide Production by Human Neutrophils.- Antiplatelet Aggregation Activity of Serum Amyloid a (SAA) Related Peptides.- Effect of Purified Serum Amyloid a on Growth and Differentiation of Transformed Cells.- II Al Protein and Light Chain Related Amyloidosis.- Primary Systemic Amyloidosis (AL) In 1990.- Comparison of the Amino Acid Sequences of Ten Kappa I Amyloid Proteins for Amyloidogenic Sequences.- Characterization of a X Al Protein and Two Amyloidgenic X Bjp in Three Cases of Immunoglobulin Amyloidosis.- Biclonality in Amyloidosis Patient Mal: One Clone Producing an Amyloidogenic, the Other a Non-Amyloidogenic Kappa L-Chain.- Complete Amino-Acid Sequence of a Kappa Light Chain Fragment Isolated from the Urine of Amyloidosis Patient Mal.- Comparative Studies of Two al Chains of Kappa-III Light Chain Origin with and Without Attached Carbohydrate (Al So124 and Al 700).- Structural Studies of two Carbohydrate-Containing Al Chains (?II) Al NoV and Al Mc.- Complete Amino-Acid Sequence of Al-Bence-Jones Protein Pol of the Lambda I Subclass.- Complete Amino-Acid Sequence of Al-Lambda 1.1 Bence-Jones Protein Ezi.- Complete Amino Acid Sequence of A A Amyloid Fibril Protein Isolated from the Liver of Amyloidosis Patient Dia.- Systemic Al Amyloidosis In A Cat.- Experimental Production of Human Amyloidosis Al.- Al Amyloid, L-Chain and L&H-Chain Deposition Diseases: Comparison of Ig Synthesis and Tissue Deposition

This issue of Primary Care: Clinics in Office Practice, devoted to Nephrology, is edited by Dr. Samuel Snyder. Articles in this issue include: Secondary hypertension; Update on ACE/ARB/DRI; Workup of proteinuria; Diagnosis and evaluation of renal cysts; NSAIDs, COX2's and the kidney; The PCP/nephrologist partnership in advancing CKD; Nosocomial AKI; Geriatric patient with CKD; Hematuria workup; The kidney in obesity; and Renal transplant in the primary care setting.

Non-neoplastic diseases are the focus of coverage in this issue of Surgical Pathology Clinics. Topics include: Non-neoplastic diseases in kidney cancer; Nephrectomy for non-neoplastic causes; Autopsy renal pathology; Practical approach to kidney donation workup; Kidney allograft pathology; Renal infections; Amyloidosis - all subtypes; Histologic classifications in renal pathology - pros and cons; Renal molecular pathology; Emerging concepts and controversies in renal pathology. This issue is intended for surgical pathologists and those with clinical practices in diagnostic renal pathology and kidney research. Anthony Chang, whose clinical practice and research is focused on renal pathology, leads this issue.