Approximately 14 million people in the UK live with some form of bladder complaint. This equates to over one in five people, so even if you don't personally experience the embarrassing and intrusive symptoms of bladder dysfunction, it is likely that you know someone who does. Bladder dysfunction does not discriminate as these problems affect all ages and genders. Despite the fact that these health issues are very common, it can be difficult to discuss them with family, friends and even a doctor. Many people suffer needlessly in silence even though there is now a wide range of investigations and treatments that can lead to effective and long-lasting symptom relief. This book guides you through the different conditions associated with bladder dysfunction, how you can help yourself, what to expect if you need to undergo investigations and the numerous evidence-based treatments that are available - both mainstream and complementary - so that you will no longer need to feel reluctant to broach the subject with your GP - meaning you can find your way back to good health.

An easy to follow step-by-step guide to the most useful surgical skills from knot tying to simple procedures. Illustrated with colour photographs and video clips to demonstrate techniques, this book makes these practical skills as clear and easy to follow as possible. Including coverage of surgical instruments, wound management and suturing, and minor surgical procedures, it also explains how to use these essential surgical skills to make the most of a surgical placement. Healthcare students or junior professionals undertaking a placement in surgery or emergency medicine will feel confident and capable, and will be able to take an active role in surgical placements. Learning basic surgical skills is important for such placements, as well as for undertaking exams such as the Membership of the Royal College of Surgeons (MRCS).

First principles chapter clearly explains the key concepts, processes and structures of the renal system. Clinical essentials chapter provides an overview of the symptoms and signs of renal disease, relevant history and examination techniques, investigations and management options. Disease-based chapters give concise descriptions of all major disorders, e.g. chronic kidney disease, each chapter introduced by engaging clinical cases that feature unique graphic narratives. Emergencies chapter covers the principles of immediate care in situations, such as hyperkalaemia and kidney stones. Integrated care chapter discusses strategies for the management of chronic conditions across primary and other care settings. Self-Assessment - 80 multiple choice questions clinical SBAs.

A complete guide to caring for your kidneys and maximizing your health. Kidney disease occurs when your kidneys are damaged and no longer function as well as they should. In the past, it was fatal, but thanks to new treatments, including dialysis and transplantation, people can live long and healthy lives. This book provides everything you need to know to help you cope with your kidney disease and maximize your health. Walter A. Hunt, a medical researcher who had kidney disease and received a kidney transplant, walks you through what science says about how you can take care of your kidneys, including what foods to avoid and what treatment options may be best for you. Also included are recommendations to help you sleep and feel better along with overall health advice. In this latest edition, Hunt adds new sections on emerging subjects, including * coping skills for caregivers * kidney disease in children * environmental causes of chronic kidney failure * conservative care for those who wish to decline treatment * related conditions like gout, depression, and sleep disturbances * diet after transplantation * how best to work with your care team * insurance issues * potential new treatments A useful guide for the healthcare professionals who work with individuals with kidney problems.

This thoughtful new book presents strategies for helping end-stage renal disease patients and their families deal with the psychosocial aspects of the chronic long-term illness. Technological advances in the treatment of this disease have offered much hope for improved quality in living which has led caregivers to have a greater concern for preserving the quality of life of their patients. In Psychosocial Aspects of End-Stage Renal Disease leaders in the field of many disciplines share knowledge and reveal problems that are still evident to them in the confrontation with this potentially fatal illness.Five comprehensive sections devote special attention to the different areas of concern for the psychosocial well-being of end-stage renal disease patients. The impact of renal disease on family relationships is covered by examining issues of family responses and coping measures such as marital and family reactions to home and hospital dialysis treatment. Ethical issues in treatment are explored, including the ethics of treatment refusal and a Jewish perspective on kidney transplants. Relations between staff and patients and a timely section on renal disease and special populations, particularly the elderly and AIDS patients, make up the final two sections of this informative volume. Professionals in all allied health disciplines will benefit from this important volume as it demonstrates a model approach, if not the definitive one, for the treatment of the psychosocial aspects of end-stage renal disease as well as other chronic illnesses.

Lecture Notes: Nephrology is a concise introduction to the fundamental principles of nephrology. An ideal study guide for medical trainees, this accessible resource combines the depth of a textbook with the accessibility of a handbook. Succinct chapters describe the clinical implications of renal physiology, examine major renal disorders and diseases, and explain a wide range of management and treatment options. A new addition to the popular Lecture Notes series, this handbook provides trainees in nephrology with core subject knowledge and enables medical students to gain a more comprehensive understanding of this complex specialty. Offers clear, easy-to-understand coverage of all relevant nephrology topics Includes MCQs and discussion around the answers, ideal for those preparing for written Internal Medicine examinations, including the certification examination of the American Board of Internal Medicine, the UK-based MRCP and the Australia and New Zealand-based FRACP examinations Features chapter summaries and numerous infographics, tables and figures Emphasises core management skills needed by medical students and junior doctors Is presented in the consistent and well-recognised Lecture Notes format

Nephrolithiasis is the third most common diagnosis involving the urinary tract, exceeded only by urinary tract infections and prostate conditions. Uric acid nephrolithiasis accounts for 5-10 % of all kidney stones in the general population in the United States (US) and is noted to be increasing in other parts of the world like Japan, previously known to have a low incidence of this condition. This increase is attributable, at least in part, to westernised eating habits. Other factors which influence development of kidney stones include age, sex and ethnicity. This book discusses in further details, the risk factors, treatment options and ways to prevent nephrolithiasis.

This book explains how hypertension affects 20-50% of the adult population in developed countries. Heart failure is the result of the hypertension's effects on the heart and it represents a growing public health problem. In this context the international scientific community is continuously struggling to develop better strategies in screening, diagnosing and treating hypertension and its deleterious effects. Thus, this field is continuously changing, with new important information being added constantly. This volume will offer both insights into the intimate mechanisms of transition from hypertension to heart failure and clinical practice advice on the prevention and treatment of heart failure in hypertensive population. The mechanisms which explain the progression from hypertension to heart failure will be also covered exhaustively by offering two chapters referring to the diagnosis of heart failure in hypertensive population and one regarding echocardiography which is the most frequently used imaging method in clinical practice. The reader will be also provided with information on cardiovascular magnetic resonance which has the unique advantage of differentiating hypertensive heart failure from other pathologies associated with increased myocardial thickness. This book is a useful tool for clinicians but also to the research community interested in heart failure and consequences of hypertension on heart who want to be up-to-date with the new developments in the field.

Concise, thorough, and easy to use, Handbook of Nephrology and Hypertension 7th Edition, provides authoritative guidance on diagnosing and treating patients with a wide range of kidney disorders and hypertension, including coverage of dialysis and transplantation. Lead editor Dr. Christopher Wilcox and his team of section editors Drs. Michael Choi, Limeng Chen, Winfred N. Williams, and Mark S. Segal oversee a group of expert authors, both faculty and fellows, who focus on common problems and challenges in this complex field. Brief, focused chapters contain abundant figures and algorithms and have been updated to reflect new findings in renal cystic diseases, new drugs used for hypertension, transplantation and renal protection, and much more. Includes new chapters on Urinalysis and Hematuria, Hypertensive Nephropathy, Drug Use in Kidney Disease, Resistant and Secondary Forms of Hypertension, and Medical Reimbursement and Economics of Nephrology Practice Contains dedicated chapters on drugs for edema, hypertension, and glomerulonephritis, as well as drugs pertaining to renal transplant, covering how to select and use drugs, doses, and adverse effects, and how prescribing should be altered in patients with renal insufficiency Features a new four-color design and more figures and algorithms throughout Shares the experience and knowledge of distinguished international authors from top universities in both the U.S. and China, with many chapters co-authored by a faculty and a fellow Enrich Your eBook Reading Experience Read directly on your preferred device(s),such as computer, tablet, or smartphone. Easily convert to audiobook,powering your content with natural language text-to-speech.

This guide is structured to assist physicians in the management of those hypertensive patients who present with specific comorbidities, such as diabetes, systolic dysfunction, obesity, renal disease, or previous cardiac events, often associated with hypertension. The clinical cases contained in this book have been selected to provide a paradigmatic set of scenarios frequently encountered in daily clinical practice, and will serve as an easy-to-access tool in applying general guidelines to individual patients, particularly in the choice of the most appropriate antihypertensive therapy. Treatment of hypertension with associated clinical conditions require specific therapies and combinations of drugs, which are necessarily different from one comorbidity to another. By discussing exemplary cases that may better represent clinical practice in a "real world" setting, and analyzing step by step the diagnostic and therapeutic process, this book will assist cardiologists and physicians in selecting the diagnostic tools and forms of treatment best suited to the individual patient and the particular cardiovascular risk profile.

Book initiates with introductory material to hemodialysis technology and its historical evolution and later on divulging into the field of biomaterials. With this background, the book discusses selection criteria of a suitable biomaterial for synthesis of haemodialysis membranes along with illustration of a complete indigenous, low cost technology for spinning of haemodialysis fibres. Well illustrated description of instruments used for membrane characterization and biomedical engineering is also provided at suitable junctures to effectively present the concept including worked out examples. Present title can be a good textbook as well as a research material for membrane as well as biomedical engineering curricula and provides coverage for appropriate undergraduate and graduate students interested in hemodialysis membranes.

Well organized and highly readable, the National Kidney Foundation Primer on Kidney Diseases has offered clear, comprehensive coverage of adult and pediatric kidney diseases for more than 25 years. The thoroughly revised 8th Edition of this authoritative, practical reference covers every relevant topic in the field, making it an excellent resource for residency, fellowship, clinical practice, and board review. It brings you completely up to date with key topics in this fast-changing field, including ongoing clinical research and changing treatment protocols. This powerful learning tool and clinical reference is a joint publication of Elsevier and the National Kidney Foundation. Covers every relevant topic in nephrology-from anatomy, physiology, and pathophysiology to diagnosis and management of kidney disease, to fluid and electrolyte disorders, hypertension, dialysis, and renal transplantation. Presents complex material in a clear, easy-to-understand manner that is both accessible for residents and fellows and comprehensive enough for practicing nephrologists. Offers new guidance for management of COVID-19 in the Viral Nephropathies chapter. Contains two new chapters on Global Kidney Disease, and Conservative Kidney Management (CKM), a palliative care option for treating kidney failure without dialysis. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Compiled by an international team of nephrologists, this reference covers a wide variety of clinical, regional, and research issues related to the epidemiology, diagnosis, and treatment of kidney disease in ethnic populations-exploring current prevention strategies, treatment outcomes, and education and training practices in Africa, South America, Asia, as well as China, India, Pakistan, and Russia. This reference also addresses specific issues pertinent to the renal healthcare of ethnic minorities in the United States, Europe, and Australia.

This book provides easy consultation and guidance for an appropriate understanding and management of endotoxic shock. Endotoxic shock results from a severe, generalized inflammatory response induced by bloodstream infection with gram-negative bacteria. However, endotoxin-induced inflammatory activation may be disconnected by Gram-Negative threats (e.g. Gram-Positive and yeast infections) as well as occur in multiple clinical scenarios like post-cardiac arrest syndrome and trauma, possibly due to gut barrier dysfunction and consequent endotoxin translocation. The clinical management is structured focusing and dedicating a chapter for antibiotics, corticosteroids, volume support, vasoactive and cardiostimulating drug, coagulopathy and nutritional support. In addition, this book is remarkable because describing polymixin b hemoperfusion points out molecular interactions, and hydrodynamics of Sorption. Each section includes *) brief pathophysiology; *) principles of management; *) key messages. Readers can find updated tips related to the diagnosis and management of endotoxic shock with a multidisciplinary approach drawing a pathway from endotoxin structure and source and the related pathophysiology of endotoxic shock underling the specific clinical aspect and focusing on medical clinical management of endotoxemia and extracorporeal removal. The book - written by international opinion leaders of this field - is addressed to healthcare providers working in intensive care and represents a point of reference for intensivists, infectious disease physicians, nephrologists and critical care nurses involved in the management of endotoxic shock and enriched with useful downloadable material.

This manual will meet the everyday needs of the wide range of medical professionals who play a role in the treatment of children referred to hospital because of renal disease. It is an easy-to-use, portable guide that will assist pediatricians, residents, and trainees in making prompt first-level management decisions. It will also prove invaluable for the adult nephrologists who care for children in many developing countries, and will serve as a teaching guide for experts when training non-subspecialists. Individual sections are devoted to the evaluation of renal disease; fluid, electrolyte, and acid-base disorders; glomerular diseases; tubular disorders; congenital, inherited, and urological disorders; consequences of renal disease; and miscellaneous topics. The text is in a bulleted format with tables and algorithms wherever possible, making it straightforward and easy to read. An appendix includes further important information such as normal values, drug dosages, and drug nephrotoxicity.

This volume focuses on the investigatory methods applied to autosomal dominant polycystic kidney disease (ADPKD), one of the most common human genetic diseases. ADPKD is caused by mutations in PKD1 and TRPP2, two integral membrane proteins that function as receptor/ion channels in primary cilia of tubular epithelial cells. Thus, ADPKD belongs to ciliopathies, a group of disorders caused by abnormal cilia formation or function. This proposed book will cover the state-of-the-art methods ranging from molecular biology, biochemistry, electrophysiology, to tools in model animal studies. Key Features Explores the role of cilia in polycystic kidney disease Focuses on myriad state-of-the-art methods and techniques Reviews specific mutations integral to this autosomal genetic disease Includes discussions of model systems

This book presents a wide variety of cutaneous features of systemic sclerosis under one cover as cutaneous manifestations are often the first to appear and help in diagnosing this condition early. It has a multidisciplinary approach as systemic sclerosis is a multi-system disorder which comes under the purview of various medical specialties like dermatology, rheumatology and nephrology. Numerous cutaneous features are illustrated with explanatory notes. This book would help the students, teachers and professionals in identification, followed by subsequent treatment and management at an early stage. Key Features Focuses exclusively on systemic sclerosis Includes diagnostic tips Explores systemic sclerosis in dark skinned people Consists of key points at the end of each chapter Discusses diagnostic algorithms and flow charts

Because of the progress in diagnostic transplantation pathology interpretation of transplant biopsies is increasingly becoming an attractive field for general surgical pathologists. The book focuses on the pathology of transplantation in the following organs: kidney, liver, lungs, heart, pancreas and small intestine. An introductory section addresses common entities that may complicate all transplant recipients such as infections, post-transplant lymphoproliferative disease and graft versus host disease, followed by 6 sections with detailed manifestations of rejection in each organ. This comprehensive, well-illustrated book serves the needs and meets the requirements of pathologists in training and those practicing in centers with limited volume of transplant biopsies in daily practice.

Kidney disease is a global health concern that affects people of all ages and races. Based on the work of the National Kidney Foundation and the Kidney Disease: Improving Global Outcomes foundation, guidelines have been developed outlining the parameters for patient care. Nutritional Therapy for Chronic Kidney Disease builds upon the discoveries made by these institutions and expands upon their recommendations to provide a comprehensive guidebook with practice protocols for individuals with kidney disease. With chapters written by expert authors drawing on their own experiences, the book: Outlines the history of kidney disease and its treatment Details the distinctions in nutrition therapy throughout the five stages of chronic kidney disease Features precise recommendations for management of the complicated renal diet in acute kidney disease Examines dietary concerns for pregnant women, children, persons with diabetes, and post-transplant patients Discusses the common metabolic pathologies associated with kidney disease, including electrolyte and acid-based disorders, bone and mineral disorders, and chronic anemia Includes chapters on obesity and physical activity, quality of life improvement in chronic kidney disease, and dietary counseling strategies Reflecting the medical community's emphasis on patient-centered care, this volume provides a complete primer on the importance of diet in maintaining kidney health and provides practical guidance to caregivers charged with devising nutritional strategies for kidney patients.

The third edition of a bestseller, this book provides insight from a wide array of international contributors in the field of pediatric nephrology. Copiously illustrated with photomicrographs and clinical diagrams, the third edition reflects current advances in the field. Each chapter contains a set of questions, directed at helping fellows succeed at the American Pediatric Nephrology Board examination. New information for this edition includes changes in treatment options for hyponatremia, and updates on hyperparathyroidism and transplantation. Text boxes highlight important "take home points" throughout the chapters. Clinical Pediatric Nephrology, Third Edition will be a valuable reference for clinicians in nephrology, pediatrics and urology, and any professional involved in the care of children with renal diseases seeking a reliable contemporary text.

Formulated by members of the International Scientific Committee of Radionuclides in Nephro-urology (ISCORN), Functional Imaging in Nephro-urology is not a textbook on uronephrology or radionuclides in nephro-urology, or even a book on new techniques in imaging. What the editor and authors provide here is a unique opportunity to evaluate the strategic management techniques (both diagnosis and follow-up) of a number of uronephrological entities. Demonstrating the experience of the authors in using various imaging modalities, and detailing the benefits and controversies which are associated with their clinical applications, this text presents management strategies based on the patient, the choice of modality, and cost implications. Detailed, well-referenced and highly illustrated, this is an important book for radiologists, nephrologists and urologists working with children and adults, specialists in renal nuclear medicine, and pediatricians.

Kidney cancer is the 10th most common cancer in Europe with overall mortality rates increasing until the late 1980s and early 1990s and thereafter, stabilised. Until recently, renal cell carcinoma (RCC) was thought to represent a monomorphic disease; however, modern genetic characterisation has demonstrated different subtypes with specific cell types and molecular metabolism. Imaging diagnostic methods are basic for staging and for new treatment strategies. Moreover, tumour biopsy has been reintroduced in the diagnostic armamentarium, mainly in patients with small masses but also when disseminated tumours need to be treated with new target therapies. Although TNM stage, Fuhrman grade and Eastern Oncology Group (ECOG) performance status are the most recognised prognostic factor in RCC, active research continues to determine new prognostic factors to classify different risks for death from RCC. Laparoscopy has gained widespread popularity because of a less morbidity and a faster post-operative convalescence. Partial laparoscopic nephrectomy is a demanding operation that can be made depending on the experience of the surgeon, the size or location of the tumour in the kidney. New robotic approaches are being introduced for nephron sparing surgery. Conversely, cardiac bypass can be necessary for resection of tumours with thrombus extending into the inferior vena cava above the level of hepatic veins. With the advent of modern ablative energies (cryotherapy or radiofrequency) for renal tumours in selected patients with percutaneous or laparoscopic techniques, it is now possible to achieve long cancer specific survival with decreased morbidity. A need for standardisation of follow-up after surgery with lifelong protocols has been recognised in last years. Finally, angiogenesis inhibitors have demonstrated a high probability of disease control in patients with metastatic renal carcinomas. Their indication as adjuvant in local advanced tumours as well as the role of nephrectomy in patients with metastatic disease is being evaluated in current clinical trials.

A much-needed, up-to-date guide to the clinical management of kidney disorders in children and adolescents, this text presents the essentials of diagnosis and treatment in this important field, with an indication of when referral to, or consultation with, the pediatric nephrologist is needed. With a team of international contributors who have had a significant global impact on the development of pediatric nephrology, this user-friendly resource takes the findings of specialists to a much wider audience in training and in primary care.