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Books > Medicine > Clinical & internal medicine > Renal medicine > General

Pancreas, Kidney and Skin Regeneration (Hardcover, 1st ed. 2017): Phuc Van Pham Pancreas, Kidney and Skin Regeneration (Hardcover, 1st ed. 2017)
Phuc Van Pham
R5,593 Discovery Miles 55 930 Ships in 10 - 15 working days

This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in diabetes, kidney and wound treatment. All chapters are contributed by pre-eminent scientists in the field and covers such topics as stem cells and cell therapy in the treatment of diabetes mellitus, kidney failure, wound and other skin aging diseases, characteristics of some kinds of stem/progenitor cells for therapy, future directions of the discussed therapies and much more. Pancreas, Kidney and Skin Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.

Textbook of Dialysis Therapy (Paperback): Jigar Shrimali Textbook of Dialysis Therapy (Paperback)
Jigar Shrimali
R3,448 Discovery Miles 34 480 Ships in 10 - 15 working days
Cardio-Renal Clinical Challenges (Paperback, Softcover reprint of the original 1st ed. 2015): David Goldsmith, Adrian Covic,... Cardio-Renal Clinical Challenges (Paperback, Softcover reprint of the original 1st ed. 2015)
David Goldsmith, Adrian Covic, Jonas Spaak
R5,278 Discovery Miles 52 780 Ships in 10 - 15 working days

In modern medicine, the aging population is prone to many simultaneous cardiovascular (CV) risk factors which often produce co-incident pathology. Nowhere is this more obvious than in the interaction between Chronic Kidney Disease (CKD), Diabetes and diverse CV diseases (CVD). This is a complex and challenging area, as the presence of CKD/diabetes promotes CVD while also complicating its treatment. The emergence of CKD as a public health priority is one of the most challenging problems of modern medicine. It is now solidly established that renal dysfunction portends a high risk for cardiovascular disease. Cardiovascular diseases remains the main cause of death in western societies and the amplification of the death risk conveyed by coexisting CKD, even though still poorly understood, appears considerable. The bidirectional link that associates renal and cardiovascular diseases, the high risk of the death signalled by their coexistence and the considerable epidemiological burden imposed by this link is at the basis of the emergence of a new discipline aiming at making the borders between nephrology and cardiovascular medicine even more permeable than before. The term Cardio-Renal Syndrome was coined around 5 years ago to try to formalize this link, and act as a stimulus to interaction between clinical teams, researchers and others to achieve better management and outcomes for all. This book takes clinical presentations and clinical problems as its base, and then discuss the evidence for best management of common clinical problems as well as the reasons for the complex interplay between the cardiac and renal systems. Moreover, it addresses the issue of organizing healthcare to maximize the opportunities for prevention and best healthcare economic returns, building on cutting edge initiatives at the Karolinska, Stockholm. The book will be of immediate value and interest to all cardiologists and renal physicians.

Kidney Development and Disease (Hardcover, 1st ed. 2017): Rachel K. Miller Kidney Development and Disease (Hardcover, 1st ed. 2017)
Rachel K. Miller
R6,969 Discovery Miles 69 690 Ships in 10 - 15 working days

Kidney Development and Disease brings together established and young investigators who are leading authorities in nephrology to describe recent advances in three primary areas of research. The first section describes the use of animal models as powerful tools for the discovery of numerous molecular mechanisms regulating kidney development. The second section focuses on nephric cell renewal and differentiation, which lead to diverse cell fates within the developing kidney, and discusses diseases resulting from the aberrant regulation of the balance between cell fate decisions. The final section concentrates on morphogenesis of the developing kidney and its maintenance after formation as well as the diseases resulting from failures in these processes. Kidney form and function have been extensively studied for centuries, leading to discoveries related to their development and disease. Recent scientific advances in molecular and imaging techniques have broadened our understanding of nephron development and maintenance as well as the diseases related to these processes.

Critical Care Nephrology (Hardcover, 3rd edition): Claudio Ronco, Rinaldo Bellomo, John A. Kellum, Zaccaria Ricci Critical Care Nephrology (Hardcover, 3rd edition)
Claudio Ronco, Rinaldo Bellomo, John A. Kellum, Zaccaria Ricci
R7,485 Discovery Miles 74 850 Ships in 12 - 17 working days

Comprehensive and clinically relevant, the 3rd Edition of Critical Care Nephrology provides authoritative coverage of the latest advances in critical care procedures for patients with renal diseases or disorders. Using common guidelines and standardized approaches to critically ill patients, this multidisciplinary reference facilitates better communication among all physicians who care for critically ill patients suffering from kidney disease, electrolyte and metabolic imbalances, poisoning, severe sepsis, major organ dysfunction, and other pathological events. Offers detailed discussions of different forms of organ support, artificial organs, infections, acute illness occurring in chronic hemodialysis patients, and much more. Places a special emphasis on therapeutic interventions and treatment procedures for a hands on clinical reference tool. Presents information clearly, in a format designed for easy reference - from basic sciences to clinical syndromes to diagnostic tools. Covers special populations such as children, diabetic patients, and the elderly. An exceptional resource for nephrologists, intensivists, surgeons, or critical care physicians - anyone who treats critically ill renal patients. Shares a combined commitment to excellence lead by Drs. Claudio Ronco, Rinaldo Bellomo, John Kellum, and Zaccaria Ricci - unparalleled leaders in this field. Addresses key topics with expanded coverage of acute kidney injury, stress biomarkers, and sepsis, including the latest developments on mechanisms and management. Provides up-to-date information on extracorporeal therapies from new editor Dr. Zaccaria Ricci. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Small Renal Mass, An Issue of Urologic Clinics, Volume 44-2 (Hardcover): Alexander Kutikov, Marc Smaldone Small Renal Mass, An Issue of Urologic Clinics, Volume 44-2 (Hardcover)
Alexander Kutikov, Marc Smaldone
R2,409 R2,207 Discovery Miles 22 070 Save R202 (8%) Ships in 12 - 17 working days

The Guest Editors have secured the top urologists to provide current clinical reviews on the latest advances in the management of small renal masses. Articles are devoted to the following topics: hereditary yndromes; trends in renal surgery; humor anatomic complexity; risk assessment; renal biopsy; active surveillance; ablation; surgical techniques; renal ischemia; lymph node dissection; complications; neoadjuvant targeted therapy for renal surgery; salvage surgery; and post-operative surveillance. Readers will come away with a succinct overview of the most clinically relevant articles and be able to immediately implement the clinical information in their practice.

Born from Kidney Transplant Mother (Paperback): Kesorn Pechrach Weaver Phd Born from Kidney Transplant Mother (Paperback)
Kesorn Pechrach Weaver Phd
R1,547 R1,457 Discovery Miles 14 570 Save R90 (6%) Ships in 10 - 15 working days
Comprehensive Clinical Nephrology (Hardcover): Tanya Walker Comprehensive Clinical Nephrology (Hardcover)
Tanya Walker
R3,639 R3,147 Discovery Miles 31 470 Save R492 (14%) Ships in 10 - 15 working days
Current Progress in Nephrology (Hardcover): Tanya Walker Current Progress in Nephrology (Hardcover)
Tanya Walker 1
R3,765 R3,255 Discovery Miles 32 550 Save R510 (14%) Ships in 10 - 15 working days
Nephrology: Theory and Practice (Hardcover): Barbara Mayer Nephrology: Theory and Practice (Hardcover)
Barbara Mayer
R3,491 R3,021 Discovery Miles 30 210 Save R470 (13%) Ships in 10 - 15 working days
Proteinuria: Basic Mechanisms, Pathophysiology and Clinical Relevance (Hardcover, 1st ed. 2016): Judith Blaine Proteinuria: Basic Mechanisms, Pathophysiology and Clinical Relevance (Hardcover, 1st ed. 2016)
Judith Blaine
R3,540 Discovery Miles 35 400 Ships in 10 - 15 working days

Recent work has begun to elucidate at the molecular level how albumin is handled by the kidney and how albuminuria develops in various proteinuric diseases including minimal change disease and focal segmental glomerulosclerosis. This volume provides a comprehensive overview of the renal handling of albumin - from basic mechanisms to the pathophysiology of proteinuric diseases. In describing the basic mechanisms of albuminuria, a particular highlight will be the focus on advanced imaging techniques such as intravital microscopy that have allowed a detailed "window" into albumin transit through the kidney. The volume will cover the epidemiological studies which show that albuminuria is a strong and independent marker of kidney disease progression and cardiovascular events, the molecular details of albumin handling in the kidney at the level of the glomerulus and the proximal tubule and the pathophysiology of proteinuric diseases including minimal change disease, membranous nephropathy, focal segmental glomerulosclerosis and diabetic nephropathy.

Acute Kidney Injury - Detection, Predictors & Long-Term Outcomes (Hardcover): Erik Pearson Acute Kidney Injury - Detection, Predictors & Long-Term Outcomes (Hardcover)
Erik Pearson
R2,763 Discovery Miles 27 630 Ships in 12 - 17 working days

Acute kidney injury (AKI) is a major health concern because it is associated with increased morbidity and mortality. While therapies for AKI have improved in recent years, the prevalence of this condition is still high and continues to increase. Considering these clinical issues, the appropriate detection and management of risk factors related to AKI are important issues for clinicians managing AKI patients. This book discusses the forms of detection, predictors and long-term outcomes for acute kidney injuries.

Informing Clinical Practice in Nephrology - The Role of RCTs (Paperback, Softcover reprint of the original 1st ed. 2015):... Informing Clinical Practice in Nephrology - The Role of RCTs (Paperback, Softcover reprint of the original 1st ed. 2015)
Mohsen El Kossi, Arif Khwaja, Meguid El Nahas
R2,733 Discovery Miles 27 330 Ships in 10 - 15 working days

Historically, clinical decisions in renal medicine have been challenged by the scarce availability of robust supportive evidence. Not only are the number of randomized controlled trials (RCTs) in Nephrology the third lowest amongst the medical specialties but in many instances the trials themselves are of poor quality. In addition, practice has been further influenced by extrapolation from the outcomes of general population clinical trials which exclude renal patients. The difference between the ideal trial participant and real complex cases encountered in daily practice is well recognized and further compounded in renal patients with complex pathophysiology - this ultimately makes decision making in this subset of patients a real challenge. Recently, there has been a growing interest in conducting well designed RCTs in different areas of renal medicine. However, though clinical guidelines are helpful in providing the clinicians with a frame of best available evidence for a clinical condition, it denies the unique nature of each individual patient. This book offers a thorough and critical appraisal and evaluation of the key published clinical trials that have shaped current practice in nephrology, dialysis and transplantation. It will help the practicing physician close the gap between the inflexible and generalized nature of clinical guidelines and the day-to-day clinical decision-making for individual patients. It will provide the clinician with the tools required to investigate and extract the appropriate guidance to apply to individual cases in daily practice. Moreover, it will help improve the ability of junior colleagues to appraise available evidence in a systematic way when there is lack of local guidelines or when the guidelines are difficult to apply due to logistic constraints or barriers. Lastly, this book will serve as a reference for key clinical trials in different areas of renal medicine together with literature and authors views of these trials and their impact on changing practice.​ 

Getting Ready for Dialysis - What you need to know (Paperback): Deepak Mittal Getting Ready for Dialysis - What you need to know (Paperback)
Deepak Mittal
R471 Discovery Miles 4 710 Ships in 10 - 15 working days
Kidney Research - Experimental Protocols (Paperback, Softcover reprint of the original 1st ed. 2009): Tim D Hewitson, Gavin J.... Kidney Research - Experimental Protocols (Paperback, Softcover reprint of the original 1st ed. 2009)
Tim D Hewitson, Gavin J. Becker
R4,160 Discovery Miles 41 600 Ships in 10 - 15 working days

As the expense of treating a growing number of end-stage kidney disease patients increases, greater attention has been paid to prevention and early treatment. The study of renal disease, however, suffers due to the complex nature of renal anatomy and physiology and the plethora of different cell types found in the kidney. In Kidney Research: Experimental Protocols, top experts in the field seek to aid researchers by providing a number of specialized techniques developed to examine this intricate system. Through both well-established and novel methods, this volume explores the preparation and culture of the main cell types used to study renal disease mechanisms, the common animal models used to mimic the various forms of human renal disease, and specific applications and techniques used in vivo and in vitro. Written in the highly successful Methods in Molecular Biology (TM) series format, the chapters contain step-by-step, readily reproducible laboratory protocols, lists of the necessary materials and reagents, and tips on troubleshooting and avoiding known pitfalls. Essential and cutting-edge, Kidney Research: Experimental Protocols delivers invaluable guidance to new and experienced laboratory researchers delving into the sophisticated study of the kidney.

Kidney Development in Renal Pathology (Paperback, Softcover reprint of the original 1st ed. 2014): Gavino Faa, Vassilios Fanos Kidney Development in Renal Pathology (Paperback, Softcover reprint of the original 1st ed. 2014)
Gavino Faa, Vassilios Fanos
R1,925 Discovery Miles 19 250 Ships in 10 - 15 working days

This volume provides a comprehensive, state-of-the art review in the field of experimental and human nephrogenesis. The book reviews new data on the effects on kidney development by neonatal asphyxia, obstructive uropathies, nephrotoxic drugs, malnutrition, underfeeding, overfeeding and provides all possible preventive measures to ensure the well-being of the kidney at birth. The book also discusses the possible implications between renal development and the insurgence of kidney disease in adult life and the correlation with renal carcinogenesis. Written by well recognized experts in their fields, Kidney Development in Renal Pathology is a valuable tool for pathologists, neonatologists, nephrologists, gynecologists and researchers with an interest in kidney diseases.

Practical Controversies in Medical Management of Stone Disease (Paperback, Softcover reprint of the original 1st ed. 2014):... Practical Controversies in Medical Management of Stone Disease (Paperback, Softcover reprint of the original 1st ed. 2014)
Margaret S. Pearle, Stephen Y Nakada
R4,024 Discovery Miles 40 240 Ships in 10 - 15 working days

Practical Controversies in Medical Management of Stone Disease addresses areas of controversy regarding the evaluation and management of recurrent stone formers and provides the best available evidence to support or refute common common drug and dietary recommendations. Aimed at dispelling common myths about preventative stone treatment, this book provides practical recommendations for the diagnositic evaluation and treatment and recurrent calcium calcium stone formers, but addresses uric acid and cystine stone formers. Written by experts in stone disease, Practical Controversies in Medical Management of Stone Disease is a concise yet comprehensive resource that provides the best, current evidence supporting medical practices regarding kidney stone prevention. The book will be of value to anyone involved in the medical care of patients with kidney stones, including urologists, nephrologists, primary care physicians, and dieticians.

Urine Proteomics in Kidney Disease Biomarker Discovery (Paperback, Softcover reprint of the original 1st ed. 2015): Youhe Gao Urine Proteomics in Kidney Disease Biomarker Discovery (Paperback, Softcover reprint of the original 1st ed. 2015)
Youhe Gao
R3,496 Discovery Miles 34 960 Ships in 10 - 15 working days

This book systematically summarizes the ideas and technologies used in urine proteome analysis. It argues that change is the core of biomarker definition since the body uses its homeostatic mechanisms to correct changes in the blood. This means that urine is probably a better source of biomarkers than blood. A roadmap to the urinary biomarker era is proposed, and researchers are reminded of the potential opportunities and risks in their study design. Kidney diseases are emphasized as they produce the most significant changes in urine. This book tries to show researchers and graduate students, who are in or entering the field, "all things considered" rather than "the current affair".

Managing Renal Injury in the Elderly Patient (Paperback, Softcover reprint of the original 1st ed. 2014): Michael Haase, Anja... Managing Renal Injury in the Elderly Patient (Paperback, Softcover reprint of the original 1st ed. 2014)
Michael Haase, Anja Haase-Fielitz
R1,792 Discovery Miles 17 920 Ships in 10 - 15 working days

As the number of people aged 65 years and above rises, physicians are increasingly confronted by elderly patients with impaired renal function, altered drug metabolism and multiple comorbidities. This book examines in detail the nature of renal injury in the elderly and its optimal management. A wide range of key topics are covered, including end-stage renal disease, diabetic nephropathy, acute kidney injury, drug metabolism and renal toxicity, dialysis and its complications and the use of renal transplantation. In addition, the assessment of glomerular filtration rate in the elderly and the role of novel renal biomarkers are carefully examined. Quality of life issues, the significance of other age-related medical problems and end of life care are also discussed. This book will be of value not only to nephrologists but also to general practitioners, medical students, intensivists, cardiologists, pharmacologists and those working in related specialties.

Dyslipidemias in Kidney Disease (Paperback, Softcover reprint of the original 1st ed. 2014): Adrian Covic, Mehmet Kanbay, Edgar... Dyslipidemias in Kidney Disease (Paperback, Softcover reprint of the original 1st ed. 2014)
Adrian Covic, Mehmet Kanbay, Edgar V Lerma
R4,568 Discovery Miles 45 680 Ships in 10 - 15 working days

Dyslipidemia in chronic kidney disease is a common clinical problem and growing in prevalence. With the recent publication of clinical practice guidelines on the management of lipid related disorders in patients affected by chronic kidney disease, an up-to-date and comprehensive resource of evidence-based literature is needed. Dyslipidemias in Kidney Disease captures the growing body of information on this subject matter. This book presents the latest clinical evidence and management guidance for patients of various demographics and stages of chronic kidney disease. Written for the nephrologist community, as well as cardiologists and general practitioners, this guide will provide practical knowledge and fill a much needed void in the literature.

Diabetes and Kidney Disease (Paperback, Softcover reprint of the original 1st ed. 2014): Edgar V Lerma, Vecihi Batuman Diabetes and Kidney Disease (Paperback, Softcover reprint of the original 1st ed. 2014)
Edgar V Lerma, Vecihi Batuman
R4,898 Discovery Miles 48 980 Ships in 10 - 15 working days

Diabetes and Kidney Disease reviews the most up-to-date research on diabetic nephropathy, the current understanding of its pathophysiology, renal structural alterations and clinical features and summarizes recent evidence-based clinical treatment modalities for the prevention and management of diabetic kidney disease. General clinical aspects are covered, as well as an overview to the novel approaches being designed by leading researchers in the field. A convenient compendium for physicians involved in the care of diabetic patients with varying degrees of kidney involvement, Diabetes and Kidney Disease is also a handy resource for medical residents and students interested in the current status and future approaches to reducing the burden of diabetes and diabetic kidney disease.

Kidney Development - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2012): Odysse Michos Kidney Development - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2012)
Odysse Michos
R4,239 Discovery Miles 42 390 Ships in 10 - 15 working days

Over the last decade the development of new molecular biology tools, advanced microscopy, live imaging and systems biology approaches have revolutionized our conception of how embryonic development proceeds. One fundamental aspect of development biology is the concept of morphogenesis: understanding how a group of multipotent cells organize and differentiate into a complex organ. In Kidney Development: Methods and Protocols, expert researchers in the field detail different approaches to tackle kidney development. These approaches include culture and live imaging aspects of kidney development, analyzing the 3-dimensional aspects of branching morphogenesis as well as nephrogenesis, manipulation of the gene/protein expression during kidney development as well as in the adult kidney, and how to assess kidney malformation and disease. Written in the highly successful Methods in Molecular Biology (TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Kidney Development: Methods and Protocols seeks to aid scientists in the further study of the process of morphogenesis which is fundamental important not only for studying developmental biology but also for regenerative medicine.

Studies on Renal Disorders (Paperback, Softcover reprint of the original 1st ed. 2011): Toshio Miyata, Kai-Uwe Eckardt, Masaomi... Studies on Renal Disorders (Paperback, Softcover reprint of the original 1st ed. 2011)
Toshio Miyata, Kai-Uwe Eckardt, Masaomi Nangaku
R6,606 Discovery Miles 66 060 Ships in 10 - 15 working days

Conditions such as oxidative stress and hypoxia, which have a generalized impact on the oxygen metabolism, have been implicated in the genesis of kidney disease. This means that deepening our understanding of the pathobiology of oxygen metabolism in such diseases could be a fruitful path towards tangible clinical benefits. Studies in Renal Disorder collects reviews from leading researchers and clinical scientists working in exactly this field, providing an overview of the latest advances. The causal role of impaired oxygen metabolism in kidney disease has numerous clinical implications. It affects our understanding of the therapeutic benefits accruing from anti-hypertensive agents; the way we control hyperglycemia/hyperinsulinemia and hyperlipidemia; and our use of dietary approaches to the correction of obesity. The defensive mechanisms against oxidative stress, such as the Nrf2-Keap1 system, and hypoxia, such as the PHD-HIF system, have recently been explored in various cells, including kidney cells. These mechanisms include intracellular sensors for oxidative stress and hypoxia. This means that novel approaches targeting these sensors may offer clinical benefits in kidney disease in which oxidative stress and/or hypoxia is a final, common pathway.

Nutrition in Kidney Disease (Paperback, Softcover reprint of the original 2nd ed. 2014): Laura D. Byham-Gray, Jerrilynn D.... Nutrition in Kidney Disease (Paperback, Softcover reprint of the original 2nd ed. 2014)
Laura D. Byham-Gray, Jerrilynn D. Burrowes, Glenn M. Chertow
R6,515 Discovery Miles 65 150 Ships in 10 - 15 working days

Nutrition in Kidney Disease, Second Edition addresses the relationships between nutrition and (1) normal kidney function and disease, (2) the progressiveness of chronic kidney disease (CKD) and strategies to prevent further compromise, and (3) the treatment and management of kidney failure especially during medical crises, such as acute kidney injury and its consequent nutritional therapies (e.g., enteral and parenteral nutrition). Demographic patterns, trends and outcomes in the current health care systems are explored in the United States and abroad. Disease prevention and management are presented over the entire lifespan, beginning with pregnancy, followed by infancy, childhood, adolescence, and adulthood, concluding with the elder years. Foundations for clinical practice are established by devoting a complete section towards conducting a comprehensive nutritional assessment, comprising of anthropometric, biochemical, clinical, physical parameters and psychosocial concerns unique to the kidney disease population. Nutritional therapy is also discussed across the spectrum of kidney disease, and pertinent aspects critical to successful management of disorders and conditions, such as bone disease, obesity, and nephrotic syndrome are explored. Nutrition in Kidney Disease, Second edition highlights cutting edge research in regards to exercise and functional outcomes, malnutrition and the inflammatory response, experimental therapies, and the use of complementary and alternative medicine, with a special emphasis on relevant preventative strategies.

Clinical Decisions in Nephrology, Hypertension and Kidney Transplantation (Paperback, Softcover reprint of the original 1st ed.... Clinical Decisions in Nephrology, Hypertension and Kidney Transplantation (Paperback, Softcover reprint of the original 1st ed. 2013)
Edgar V Lerma, Mitchell Rosner
R6,035 Discovery Miles 60 350 Ships in 10 - 15 working days

Through case presentations and a question and answer format, Clinical Decisions in Nephrology, Hypertension and Renal Transplantation provides a state of the art, updated reference for the optimal management of patients with diseases of the kidneys, and hypertension. This volume starts with the assessment of the patient, focusing on history and physical examination. Subsequently, cases depicting various clinical syndromes and/or diseases are presented, with questions centering on the appropriate diagnostic and treatment strategy. This sets the stage for a 'Socratic approach' to learning between the attending physician and the house staff or medical student. This is the only book featuring problem-oriented true to life clinical cases in this format to cover nephrology, hypertension and kidney transplantation. Written by renowned actively practicing clinicians, this unique reference is both comprehensive and concise and will be of great value to hospitalists and internists, as well as students, and interns/residents rotating in nephrology and internal medicine. Clinical practitioners, in the fields of critical care and hypertension specialists would also find this of value.

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