Written by child neurologists, this comprehensive, multi-authored volume on autism systematically discusses the classification, epidemiology and neurobiology of autism. Autism lacks a unique etiology or specific pathology, so the behaviorally defined social deficits, language impairments and repetitive behaviors that define autism are explored from a developmental neurology perspective. The evidence suggesting that autism is a disorder of neuronal development is reviewed by experts on the genetics, neuroanatomy and neuroradiology, neurochemistry, immunology, and neurophysiology of autism. Chapters provide comprehensive reviews of the common neurological problems associated with autism such as epilepsy, sleep disturbances and motor and sensory deficits. Neuropsychological assessment, medical and psychopharmacologic management, educational and behavioral interventions, and outcome are discussed within the clinical content of the practising neurologist. The research agenda needed to understand the neurology of autism is emphasized throughout the book and in the conclusion.

Brain, Mind, and Developmental Psychopathology in Childhood, part of the International Association of Child and Adolescent Psychiatry and Allied Professions' book series "Working with Children & Adolescents" edited by Elena Garralda and Jean-Philippe Raynaud, aims to help advance knowledge on the connections between brain, mind, and development psychopathology in children and young people, an area of high relevance across different contexts around the world. It outlines brain mechanisms underlying children's ability to regulate behavior, emotions, interactions with others, responses to stress, and child psychiatric disorders. The book contains expert views supported by empirical evidence, and there is an emphasis on drawing out the clinical implications. It brings together knowledge from a variety of disciplines on bodily and brain processes that underlie developmental and psychiatric disorders in children and young people. Chapters include conceptual and empirical discussion of the biological and psychological influences on developmental psychopathology in childhood, clinical updates focusing on the biological underpinnings of individual child neuropsychiatric disorders as well as integrating biological and psychological therapies in child mental health. The book also discusses broader psychological/social problems, with chapters on the effects of child maltreatment in the developing brain, an update on understanding and management of self-harm, and advocacy papers on learning disorders and child and adolescent mental health.

Cancer chemotherapy frequently attacks the gastrointestinal tract. Many of the possible side-effects reduce the patient's quality of life, may limit acceptance of further drug administration, and even life-threatening complications must be considered. This book is the proceedings of the Falk Workshop 'Side-effects of Chemotherapy on the Gastrointestinal Tract: Pathogenesis and Therapy', held in Freiburg, Germany, on October 11, 2002 (Part IV of the Freiburg Gastroenterology Week). Chapters by pathologists, pharmacologists, oncologists and gastroenterologists will improve our understanding of the effects of anticancer agents on the organs of the gastrointestinal tract and help to compensate for chemotherapy-induced adverse effects.

This book discusses the main milestones of early brain development and the emergence of consciousness, within and outside the mother's environment, with a particular focus on the preterm infant. These insights offer new perspectives on issues concerning fetal pain, awareness in newborns, and the effects of current digital media on the developing infant brain. Among the topics covered: * Brain patterning, neural proliferation, and migration. * The stress of being born and first breaths. * The stream of consciousness. * Parenting and stimulating the brain of the child. * The moral status of the fetus and the infant. Infant Brain Development is an excellent resource for researchers, clinicians and related professionals, and graduate students across a variety of disciplines including developmental psychology, pediatrics, neurobiology, neuroscience, obstetrics, nursing and medical ethics. It is written with historic and philosophical remarks of interest for a broad readership. --- "This book is a joy to read for anyone interested in understanding where biology is heading in the 21st century, and it is essential for those who work in child development." Eric Kandel, University Professor, Columbia University, Co-Director, Mortimer B. Zuckerman Mind Brain Behavior Institute, Nobel Laureate in Medicine 2000 "With the precision of a scientist, the depth of a philosopher, and the heart and sensitivity of a pediatrician, Hugo Lagercrantz weaves a story as readable and engrossing as any mystery novel, linking brain, genes, the environment, and behavior to explain the development of the mind of a newborn. A tour de force!" Patricia K. Kuhl, The Bezos Family Foundation Endowed Chair in Early Childhood Learning, Co-Director, Institute for Learning & Brain Sciences, University of Washington "This book is a noble and valiant effort by Dr. Lagercrantz to explain the immensely complex issue of normal and pathological development of the human brain in simple terms that are accessible to the general public." Pasko Rakic, Duberg Professor of Neuroscience and Neurology, Yale University School of Medicine

This book is devoted exclusively to differential diagnosis in pediatric dermatology. It covers the full range of relevant conditions: inherited skin disorders; nevi; viral, bacterial, fungal, and parasitic infections; acne; allergic diseases; autoimmune skin disorders; connective tissue diseases; tumors; and miscellaneous conditions. Each comparison addresses the differential diagnosis between two (or occasionally three or four) dermatological conditions, containing between two and six images and a short text emphasizing the clinical differences between the diseases in question. At the end of each chapter, a summary highlights one or two characteristics essential for the differential diagnosis. The author is an expert who, since 1982, has been responsible for a column devoted to the differential diagnosis of pediatric dermatology in the European Journal of Pediatric Dermatology. The volume will represent an ideal tool for pediatric dermatologists, pediatricians, and GPs, and will help them in the diagnostic process.

This essential guide provides accessible, concise, evidence-based guidelines on Atttention Deficit Hyperactivity Disorder (ADHD), offering a deeper scientific understanding of the condition and its consequences. It offers ideas and insights for managing the condition in daily family life and promoting the most effective self-regulation strategies for children and adolescents, allowing parents to better understand the origins of their child's behaviour and avoid potential negative consequences. In this straightforward text, Capodieci and Re set out the basic theories on ADHD and cover key topics including parent-child relationships, helping children understand their condition, friendships with peers, comorbidities, classroom strategies, and how families and professionals can best work together. Taking into account the most recent updates to the DSM-5 definition of ADHD, the authors emphasise the importance of a multifocal approach to the treatment of ADHD, involving the child's teachers, parents and peers, to better develop family and peer relationships. They offer strategies for the classroom, for good sleep and for healthy eating and physical activity, and support for any other learning, language, movement and emotional problems an ADHD child might have. Understanding ADHD will be essential reading for parents of children with ADHD, as well as health, education and social care professionals involved in the field.

Clubfoot is a common deformity but remains unsolved. Detailed epidemiology has been described to assess the socio-economic impact. All corrective methods are enumerated, highlighting their efficacy and pitfalls. The importance of each clubfoot case being different and the means of dealing it is emphasized upon. This is a comprehensive book on Clubfoot with the types and their mode of treatment extensively discussed. Also, Clubfoot differences during birth, additional birth defects, weight bearing effect with age, previous scars, trauma and other complications are covered. Key Features A comprehensive book on Clubfoot Explained the different kinds of clubfoot Evidence based description of each clubfoot being different Updated with the latest treatment techniques Comparative analysis of various treatment options

Since the early 1940s, when first identified as childhood psychosis and autistic psychopathy, autism spectrum disorder (ASD) has continued to burgeon into a major focus of inquiry and interest among researchers, practitioners, and the public alike. With each passing decade, the number of scholarly articles addressing ASD and related disabilities continues to soar. Today, thousands of papers on autism are published annually across various disciplines and journals, making it challenging - if not impossible - to keep pace with, let alone synthesize, all the latest developments. Based on a solid historical foundation of autism theory and research, the International Handbook of Autism and Pervasive Developmental Disorders integrates the broad scholarly base of literature with a trenchant analysis of the state of the field in nosology, etiology, assessment, and treatment. Its expert contributors examine recent findings and controversies (e.g., how prevalent autism actually is), along with longstanding topics of interest as well as emerging issues. Coverage includes: A survey of diagnostic criteria and assessment strategies. Genetic, behavioral, biopsychosocial, and cognitive models. Psychiatric disorders in persons with ASD. Theory of mind and facial recognition. Diagnostic instruments for assessing core features and challenging behaviors. Evidence-based psychosocial, pharmacological, and integrative treatments. Interventions specifically for adults with ASD. Training issues for professionals and parents. A review of findings of successful and promising therapies, coupled with guidance on how to distinguish between dubious and effective treatments. The International Handbook of Autism and Pervasive Developmental Disorders is an indispensable resource for researchers, professors, graduate students, and allied practitioners in clinical child and school psychology, child and adolescent psychiatry, education, social work, rehabilitation, pediatric medicine, and developmental psychology.

The first resource to focus on pediatric and adolescent gynecology from the perspective of frontline health care providers. This one-of-a-kind, quick-access guide for APRNs and Physician Assistants delivers current patient assessment and management information for the specialized field of pediatric and adolescent gynecology (PAG). Underscoring the need to consider the unique questions and concerns of the younger population as distinct from those of adults, this authoritative resource addresses a multitude of common PAG patient questions and chief complaints, including acute and chronic conditions and commonly prescribed medications and their potential side effects. Helping to foster sound decision-making in triage settings, chapters highlight red flags to consider. They include a list of pertinent questions to ask the patient, provide assessment directives, recommend appropriate interventions and/or delegation as needed, and describe commonly prescribed medications. Chapters also present considerations for special populations, particularly those who may be at a higher risk for gynecologic problems, medication side effects, and/or medication interactions. To facilitate ease of use, this guide is organized into chapters based on medication or chief complaint. Appendices deliver useful templates for effective telephone encounters and documentation, home care instructions post-procedure, a supply checklist for office treatments, administration and follow-up care for vaccines and injections, at-home medication instructions, and more. Key Features: Provides a unique focus on common PAG concerns for APRNs and Physician Assistants Describes management guidelines for key complaints Organized in quick-access format with bulleted information, short paragraphs, charts and tables, and references for additional information Covers medication management and side effects Focuses extensively on hormonal contraceptive options Includes information on special pediatric populations Offers several useful Appendices with downloadable practice tools

Prevailing taboos about sex and the misconception that inappropriate sexual behavior is always a sign of sexual abuse inhibits frank conversation and often leads families to hide problems.

Here William Friedrich, with more than 25 years of experience in the field, offers a research-based and clinically-proven method for assessment, diagnosis, and intervention with children and their families. This book distinguishes itself by Friedrich's emphasis on addressing sexual behavior problems from an attachment perspective.

This means that, whenever possible, inappropriate sexual behavior is considered in light of larger family dynamics, emotional security, and child development. It also implies that family therapy is the ideal treatment modality. An important part of helping a child who exhibits inappropriate behavior involves guidance and reinforcement in the home. Friedrich shows therapists how to include the whole family in the process while not endangering the child or alienating the family.

A key feature of Children with Sexual Behavior Problems is the Assessment and Treatment Manual that constitutes the second part of the book. Grounded in the research-based perspective articulated in Part 1, the Manual puts Friedrich's insights into practice. Clear guidelines for evaluation and diagnosis are offered and a wealth of forms for clinicians and clients are included in order to structure therapeutic work.

1. A guide to managing paediatric surgical patients in a remote and rural setting 2. Includes guidance on differences in presentation and problems relating to the Tropical environment 3. A key resource in understanding paediatric surgical patients needs when being managed remotely

Biochemical parameters represent better, precise, and objective tools toward the assessment of the nutritional status of children in comparison to anthropometric, clinical, and dietary methods. They constitute laboratory tests to estimate the concentration of circulating nutrients in body fluids. Biochemical parameters are suggestive of acute or subclinical conditions when other methods of nutritional assessment fail to interpret the condition. These parameters exhibit substantial variability in their reproducibility. Moreover, these parameters are novel tools in the hands of clinicians for screening of the nutritional status of children. Key Features Covers the latest biochemical parameters for nutritional assessment Updated content is useful for clinicians, nutritionists, and general practitioners A unique and concise treatise covering descriptive and research-based work on a crucial health issue of worldwide prevalence About the Author Anil Gupta, PhD, is the Dean of Research at Desh Bhagat University and Professor and Head, Department of Physiology and Biochemistry at Desh Bhagat Dental College and Hospital, Mandi Gobindgarh, Punjab, India.

Aggressive behavior among children and adolescents has confounded parents and perplexed professionals-especially those tasked with its treatment and prevention-for countless years. As baffling as these behaviors are, however, recent advances in neuroscience focusing on brain development have helped to make increasing sense of their complexity.

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Focusing on their most prevalent forms, Oppositional Defiant Disorder and Conduct Disorder, "Disruptive Behavior Disorders" advances the understanding of DBD on a number of significant fronts. Its neurodevelopmental emphasis within an ecological approach offers links between brain structure and function and critical environmental influences and the development of these specific disorders. The book's findings and theories help to differentiate DBD within the contexts of normal development, non-pathological misbehavior and non-DBD forms of pathology. Throughout these chapters are myriad implications for accurate identification, effective intervention and future cross-disciplinary study.

Key issues covered include:

Gene-environment interaction models.Neurobiological processes and brain functions.Callous-unemotional traits and developmental pathways.Relationships between gender and DBD.Multiple pathways of familial transmission.

"Disruptive Behavior Disorders" is a groundbreaking resource for researchers, scientist-practitioners and graduate students in clinical child and school psychology, psychiatry, educational psychology, prevention science, child mental health care, developmental psychology and social work.

Psychiatric disorders in adolescents are an important social problem which is relevant to almost all healthcare professionals. According to the results of The National Comorbidity Survey-Adolescent Supplement (NCS-A), the lifetime prevalence of anxiety, behavior, mood, and substance use disorders among adolescents was 31.9%, 19.1%, 14.3%, and 11.4%, respectively. Approximately 40% of participants in this survey with one class of disorder also met criteria for another class of lifetime disorder. Comorbidity is increasingly recognized as a key feature of mental disorders among adolescents. Female adolescents are more likely than males to have mood and anxiety disorders, but less likely to have behavioral and substance use disorders. Regretfully, medical professionals are not sufficiently trained about adolescent psychiatric disorders. For example, primary care providers correctly identify less than a fourth of youth with a depressive or anxiety disorder. Also, many clinicians underestimate the importance of the problem of adolescent psychiatric illnesses and suicidal behavior. Lack of skilled medical providers impedes the delivery of needed services to adolescents with mental health issues. This coupled with a lag in the ability of primary health care services to incorporate psychiatric interventions, and a failure of public health initiatives to pay attention to adolescent mental health problems has led to continuing gaps in care over decades despite the public pronouncements of needs. In this book you will find relevant information for health professionals, since we believe that the mental health of adolescents is essential for sustaining healthy and productive societies.

As an essential guide to paediatric haematology, this concise text offers a quick and reliable source of practical information for clinicians. Covering all blood disorders in children, the contents are structured to include all the major disease groups and include introductory chapters on normal haemopoiesis, normal coagulation, infections and transfusion. Whilst the text focuses on practical management, sufficient background information is given to enable trainees to care effectively for patients. Essential Paediatric Haematology is an ideal text for haematologists and paediatricians in training and a valuable source of reference for other health care professionals.

Together with Consulting Editor Dr. Bonita Stanton, Drs. Steven Kairys and Arturo Brito have put together a comprehensive issue that addresses Vulnerable Children in the United States. Expert authors have contributed clinical review articles on the following topics: Adverse Childhood Experiences and Outcomes; Abuse and Neglect/Foster Care/Family Violence; Homelessness/Street/Children/Undocumented/Community Violence; 20 Questions (and Answers) About Media Violence and Cyberbullying; Autism as a Representative of Disability; Addiction including Tobacco and Drugs in Children; Food Insecurity and the Impact on Child Health; Guns and School Violence; The Vulnerability of Children; The Vulnerability of LGBTQ Children; Implicit Bias Impact on Children; Supporting Immigrant Children and Youth: What Pediatricians Can Do; and Human Trafficking. Readers will come away with the information they need to improve outcomes in vulnerable pediatric patients.

Chronic Myeloid Leukemia (CML) remains a key model for the improved understanding of the pathophysiology of a malignancy at a molecular level and has been used by researchers to develop a variety of therapies and therapeutic assessment methods. This concise, readable guide assembles and synthesizes the latest developments and trends in the treatment of CML and provides an authoritative and convenient summary of the latest progress in imatinib trials, the molecular monitoring of CML responses, and the engineering of new therapies to overcome resistance and improve patient care. Providing critical insight and exploration of models that will enhance the cancer community at large, this source: stands as the only source to focus on post-Gleevec developments in CML therapeutics collects information from the forefront of the field-helping busy clinicians make informed management decisions supplies critical research from recognized opinion leaders on the topic provides an overview of the current status of new transplant modalities contains a vivid selection of color photographs

This comprehensive reference uses an ecological perspective to sort out the complex mix of biological, psychological, social, and other factors influencing adolescent health as well as shaping professional responses to the needs of adolescents. Describing critical concerns at the global level and innovative strategies from selected countries, the book urges readers to develop and support practices and policies to enhance optimal youth development. Expert coverage centers on key areas: the global state of adolescent health and development, adolescent health issues and public health answers, making health systems more responsive to youth, and improving school health services. And bedrock themes such as social determinants of health, young people's right to health care, and health and gender disparities are discussed throughout these chapters. Included among the topics: * The epidemiology of adolescent health * Adolescent sexual health and sexuality education * Restorative justice and the mental wellbeing of adolescents * Critical issues in adolescent nutrition: needs and recommendations * Towards an adolescent competent workforce * Pairing children with health services: the changing role of school health services in the 21st century The International Handbook on Adolescent Health and Development is essential to medical schools, public schools, and college libraries; teaching faculty; graduate and post-graduate students in public health, medicine, social work, other behavioral sciences and health disciplines (e.g., nursing, allied heath); as well as practitioners interested in better orienting their services to the health needs of adolescents.

The aim of this book on psychotherapies with children and families is to present a comprehensive overview of the current array of intervention approaches in the child mental health field. There is a focus on the integration of theory, research, and practice throughout the book. The book proceeds from the more global pre sentations of basic theoretical approaches to applications of these approaches with specific problems and populations. It then presents more integrated intervention approaches and overviews of the research literature. One of the unique features of this book is its focus on future directions for each approach, both in clinical prac tice and in research. A second unique feature is its structured format across di verse approaches with a focus on empirical validation of approaches. Another innovation is the presentation of interventions that integrate major components of different theoretical approaches. Thus, the book reflects the current trends in the field of interventions with specific problems and populations, empirical valida tion of the approach, and the integration of treatment approaches. There are five major sections in this book. Part I consists of four chapters that address a variety of issues related to child psychotherapy. Chapter 1 by the editors examines the historical roots of child psychotherapy and explores current trends in the treatment of diverse child disorders. It emphasizes the movement to "treat ments that work" and sets the stage for the chapters that follow."

This book investigates language disorders in children who speak languages other than, or in addition to, English. The chapters in the first section of the volume focus on language disorders associated with four different syndromes in multilingual populations and contexts. This section discusses language disorders associated with autism spectrum disorders, Down syndrome, fetal alcohol syndrome and Williams syndrome. The chapters in the second section of the book relate to language impairment in children who speak diverse languages, although the issues they address are relevant across languages and cultural contexts. The book also reviews assessment procedures and intervention approaches for diverse languages, including Bengali, Cantonese, French, Spanish, and Turkish. The volume aims to stimulate thoughtful clinical practice and further research in language disorders in multilingual populations.

This book investigates language disorders in children who speak languages other than, or in addition to, English. The chapters in the first section of the volume focus on language disorders associated with four different syndromes in multilingual populations and contexts. This section discusses language disorders associated with autism spectrum disorders, Down syndrome, fetal alcohol syndrome and Williams syndrome. The chapters in the second section of the book relate to language impairment in children who speak diverse languages, although the issues they address are relevant across languages and cultural contexts. The book also reviews assessment procedures and intervention approaches for diverse languages, including Bengali, Cantonese, French, Spanish, and Turkish. The volume aims to stimulate thoughtful clinical practice and further research in language disorders in multilingual populations.

This pioneering book, now in its fourth edition, presents the cutting-edge developments in pediatric nuclear medicine. Thoroughly revised and updated, it retains the fundamentals that anchor the book s distinguished reputation and includes the latest advances in PET/CT, SPECT, hybrid imaging, and molecular imaging. "Pediatric Nuclear Medicine and Molecular Imaging, Fourth Edition," is an excellent resource for nuclear medicine physicians, diagnostic radiologists, pediatricians, and residents and fellows.

The Fourth Edition features:

. 16 new chapters, including PET and PET/CT in Children and Young Adults; Lymphoscintigraphy; Skeletal Scintigraphy; Neuroblastoma; Lymphomas and Lymphoproliferative Disorders; Functional Imaging of Pediatric Musculoskeletal Tumors; Solid Tumors in Childhood; Pediatric Molecular Imaging; Combined PET/MRI in Childhood; Radiation Exposures; Radiation Protection in Pediatric Nuclear Medicine; and Dose Optimization in Pediatric Nuclear Medicine.

. Discussion of the use of image fusion and hybrid imaging in children.

. Strategies for communicating potential radiation risk to patients, families and members of the healthcare team.

. Methods to optimize pediatric radiopharmaceutical administered doses and improve image quality.

S. Ted Treves, MD, is Professor of Radiology at Harvard Medical School, Founder and Former Chief, Division of Nuclear Medicine and Molecular Imaging, Children s Hospital Boston (1970-2011). In 2013, he received the Society of Nuclear Medicine and Molecular Imaging s Georg Charles de Hevesy Nuclear Pioneer Award for outstanding contributions to the field of Nuclear Medicine."

For more than 30 years, the highly regarded Secrets Series (R) has provided students and practitioners in all areas of health care with concise, focused, and engaging resources for quick reference and exam review. Written by Drs. Richard A. Polin and Mark F. Ditmar, Pediatric Secrets, 7th Edition, features the Secrets' popular question-and-answer format that also includes lists, tables, pearls, memory aids, and an easy-to-read style - making inquiry, reference, and review quick, easy, and enjoyable. The proven Secrets Series (R) format gives you the most return for your time - succinct, easy to read, engaging, and highly effective. Fully revised and updated throughout, including protocols and guidelines that are continuously evolving and that increasingly dictate best practices. Practical, up-to-date coverage of the full range of essential topics in the practice of pediatrics. Top 100 Secrets and Key Points boxes provide a fast overview of the secrets you must know for success in practice and on exams. Features bulleted lists, mnemonics, practical tips from leaders in the field - all providing a concise overview of important board-relevant content. Portable size makes it easy to carry with you for quick reference or review anywhere, anytime. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

This issue of PET Clinics focuses on PET Imaging in Pediatric Patients and is edited by Drs. Hongming Zhuang and Abass Alavi. Articles will include: Promising New PET tracers in the evaluation of pediatric disease; F-DOPA PET/CT in the management of congenital hyperinsulinism; Emerging roles of PET/MRI in pediatric hospital; Roles of FDG PET/CT in the management of posttransplant lymphoproliferative disease in pediatric patient; FDG-PET/CT in the management of pediatric lymphoma; Preparation and logistic consideration in performing PET/CT and PET/MRI in pediatric patients; PET/CT in the evaluation of FUO and infectious/inflammatory disease in pediatric patients; Roles of PET/CT in the evaluation of neuroblastoma; Potential Roles of Total Body Imaging in Pediatric Diseases and Disorders; PET/CT in the Management of Pediatric Sarcomas; Pediatric Cardiac PET Imaging; Dosimetry between PET/CT and PET/MRI: Implications in Pediatric Imaging; Essential Role of Global Disease Assessment in Assessing Systemic Disorders, and more!