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Books > Medicine > Clinical & internal medicine > Paediatric medicine > General

Treating Childhood Psychopathology and Developmental Disabilities (Hardcover, 2009 ed.): Johnny L. Matson, Frank Andrasik,... Treating Childhood Psychopathology and Developmental Disabilities (Hardcover, 2009 ed.)
Johnny L. Matson, Frank Andrasik, Michael L. Matson
R4,105 Discovery Miles 41 050 Ships in 18 - 22 working days

Child psychology is a constantly expanding field, with dozens of specialized journals devoted to major disorders springing up in recent years. With so much information available and the prospect of overload inevitable researchers and clinicians alike need to navigate the knowledge base with as much confidence as they do the nuances of diagnosis and their young clients complex social, emotional, and developmental worlds.

Treating Childhood Psychopathology and Developmental Disabilities fills this need by summarizing and critiquing evidence-based treatment methods for pediatric patients from infancy through adolescence. After a concise history of evidence-based treatment, promising new trends, and legal/ethical issues involved in working with young people, well-known professors, practitioners, and researchers present the latest data in key areas of interest, including: (1) Cognitive-behavioral therapy and applied behavior analysis. (2) The effects of parenting in treatment outcomes. (3) Interventions for major childhood pathologies, including ADHD, PTSD, phobias, anxiety, depression, bipolar disorder, and conduct disorder. (4) Interventions for autistic spectrum disorders and self-injuring behaviors. (5) Techniques for improving communication, language, and literacy in children with developmental disabilities. (6) Treatments for feeding and eating disorders.

This comprehensive volume is an essential resource for the researcher s library and the clinician s desk as well as a dependable text for graduate and postgraduate courses in clinical child, developmental, and school psychology.

(A companion volume, Assessing Childhood Psychopathology and Developmental Disabilities, is also available.)"

Progress in Behavioral Health Interventions for Children and Adolescents, An Issue of Pediatric Clinics of North America,... Progress in Behavioral Health Interventions for Children and Adolescents, An Issue of Pediatric Clinics of North America, Volume 69-4 (Hardcover)
Xiao-Ming Li, Sayward Harrison
R1,269 Discovery Miles 12 690 Ships in 10 - 15 working days

In this issue of Pediatric Clinics of North America, guest editors Drs. Xiaoming Li and Sayward Harrison bring their considerable expertise to the topic of Progress in Behavioral Health Interventions for Children and Adolescents. Nearly three-quarters of adult mental health disorders have their onset during childhood, where treatment becomes more difficult and has greater social, educational, and economic consequences over time. This issue provides the information and resources needed to identify and treat mental health and clinical issues in children, with the goal of improving outcomes. Contains 16 relevant, practice-oriented topics including leveraging technology in novel interventions for autism spectrum disorder; childhood obesity prevention and treatment; parental rules, parental routines, and children's (0-12 years) sleep and screen time; family-based preventions and interventions for child emotional and behavioral functioning in families facing stress/trauma; integrating behavioral health in primary care; and more. Provides in-depth clinical reviews on behavioral health interventions for children and adolescents, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Cerebral Palsies - Epidemiology and Causal Pathways (Hardcover): Fiona Stanley, Eve Blair, Eva Alberman Cerebral Palsies - Epidemiology and Causal Pathways (Hardcover)
Fiona Stanley, Eve Blair, Eva Alberman
R1,591 Discovery Miles 15 910 Ships in 18 - 22 working days

This is a clinical text about the commonest physical disability - the cerebral palsies. It follows up on the authors' earlier work The Epidemiology of the Cerebral Palsies, and its focus is still on epidemiology. In Cerebral Palsies: Epidemiology and Causal Pathways the authors offer:
Guidance on how best to study causes
Advice on how to use the massive amount of information available internationally
Novel ways to collect and analyse data
A complete review of all published data on trends in the cerebral palsies
New ways of thinking about causal pathways in the cerebral palsies which suggest possible new prevention pathway
A chapter devoted to systematic management of the cerebral palsies.
This is a timely update and an essential guide to good epidemiological research into cerebral palsies and related areas.

Gene-Based Therapies for Pediatric Blood Diseases, An Issue of Hematology/Oncology Clinics of North America, Volume 36-4... Gene-Based Therapies for Pediatric Blood Diseases, An Issue of Hematology/Oncology Clinics of North America, Volume 36-4 (Hardcover)
Nirali N Shah, Sung-Yun Pai
R2,235 Discovery Miles 22 350 Ships in 10 - 15 working days

In this issue of Hematology/Oncology Clinics, guest editors Drs. Sung-Yun Pai and Nirali N. Shah bring their considerable expertise to the topic of Gene-Based Therapies for Pediatric Blood Diseases. Top experts in the field cover key topics such as CAR T-cell therapy: current status; engineered T cells; NK-cell therapy; hemoglobinopathies: beta-thalassemia, sickle cell disease; hemophilia A/B; primary immunodeficiencies; and more. Contains 14 relevant, practice-oriented topics including the evolution of gene therapy; viral vectors in hematopoietic stem cell gene therapy; gene editing in hematopoietic stem cells; nonintegrating vectors and engineered capsids; regulatory aspects of gene therapy; and more. Provides in-depth clinical reviews on gene-based therapies for pediatric blood diseases, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Assessing Childhood Psychopathology and Developmental Disabilities (Hardcover, 2009 ed.): Johnny L. Matson, Frank Andrasik,... Assessing Childhood Psychopathology and Developmental Disabilities (Hardcover, 2009 ed.)
Johnny L. Matson, Frank Andrasik, Michael L. Matson
R4,143 Discovery Miles 41 430 Ships in 18 - 22 working days

Not long ago, conducting child assessment was as simple as stating that the child gets along with others or the child lags behind his peers . Today s pediatric psychologists and allied professionals, by contrast, know the critical importance of using accurate measures with high predictive quality to identify pathologies early, form precise case conceptualizations, and provide relevant treatment options.

Assessing Childhood Psychopathology and Developmental Disabilities provides a wide range of evidence-based methods in an immediately useful presentation from infancy through adolescence. Noted experts offer the most up-to-date findings in the most pressing areas, including: (1) Emerging trends, new technologies, and implementation issues. (2) Interviewing techniques and report writing guidelines. (3) Intelligence testing, neuropsychological assessment, and scaling methods for measuring psychopathology. (4) Assessment of major pathologies, including ADHD, conduct disorder, bipolar disorder, and depression. (5) Developmental disabilities, such as academic problems, the autism spectrum and comorbid pathology, and self-injury. (6) Behavioral medicine, including eating and feeding disorders as well as pain management.

This comprehensive volume is an essential resource for the researcher s library and the clinician s desk as well as a dependable text for graduate and postgraduate courses in clinical child, developmental, and school psychology.

(A companion volume, Treating Childhood Psychopathology and Developmental Disabilities, is also available to ensure greater continuity on the road from assessment to intervention to outcome.)"

Families, Physicians, and Children with Special Health Needs - Collaborative Medical Education Models (Hardcover): Rosalyn B.... Families, Physicians, and Children with Special Health Needs - Collaborative Medical Education Models (Hardcover)
Rosalyn B. Darling, Margo Peter
R2,560 Discovery Miles 25 600 Ships in 18 - 22 working days

Families of children with special health needs frequently cite difficulties in their communications with physicians and other medical professionals. Indeed, parents of high-risk, chronically ill, and disabled infants often regard interactions with health care providers as one of the most stressful parts of their early experiences with their children.

This volume was designed to present a variety of medical education approaches used to overcome this problem. After providing an overview of some of the difficulties faced by physicians and families of children with special health needs in their interactions with one another, the volume examines a number of useful medical education models. The models and viewpoints presented include those of physicians, early intervention professionals, professionals with backgrounds in education, psychology, and sociology, and parents. This volume is invaluable to those involved in designing and evaluating medical education approaches, and those developing public policy for children and the family.

Pediatric Nephrology, An Issue of Pediatric Clinics of North America, Volume 69-6 (Hardcover): Tej Mattoo Pediatric Nephrology, An Issue of Pediatric Clinics of North America, Volume 69-6 (Hardcover)
Tej Mattoo
R1,269 Discovery Miles 12 690 Ships in 10 - 15 working days

In this issue of Pediatric Clinics, guest editor Tej Mattoo brings considerable expertise to the topic of Pediatric Nephrology. Provides in-depth reviews on the latest updates in Pediatric Nephrology, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

Playing the Unconscious - Psychoanalytic Interviews with Children Using Winnicott's Squiggle Technique (Paperback, New):... Playing the Unconscious - Psychoanalytic Interviews with Children Using Winnicott's Squiggle Technique (Paperback, New)
Michael Gunter
R1,093 Discovery Miles 10 930 Ships in 10 - 15 working days

This book argues that the squiggle game enables the therapist in most cases to make contact with a child with particular ease. Often, if the child takes up the suggestion, an intense dialogue develops which gives insight into the inner situation, even in the cases where the child is consciously very reserved and in which the talk emerging from the squiggle game seems to be unproductive, the pictures offers a chance to start talking about precisely why he or she shows such reserve. The book explains the importance of setting up the psychotherapeutic interview situation to be playful in character, making it fun for both therapist and child. The squiggle game makes this easier because it generates a playful atmosphere which nevertheless has a very serious side to it.Including comprehensive examples from the author's practice, this book is destined to become the definitive source for using Winnicott 's squiggle game in clinical practice.

Modern Approach to Pediatrics (Hardcover): Alice Kunek Modern Approach to Pediatrics (Hardcover)
Alice Kunek
R3,357 R3,034 Discovery Miles 30 340 Save R323 (10%) Ships in 18 - 22 working days
Preventing Youth Problems (Hardcover, 2003 ed.): Anthony Biglan, Margaret C. Wang, Herbert J. Walberg Preventing Youth Problems (Hardcover, 2003 ed.)
Anthony Biglan, Margaret C. Wang, Herbert J. Walberg
R1,411 Discovery Miles 14 110 Ships in 18 - 22 working days

Preventing Youth Problems provides information needed to prevent five of the most common, costly, and dangerous problems of adolescence: anti-social behavior, tobacco use, alcohol and drug abuse, and sexual behavior that risks disease and unwanted pregnancy. Over the past thirty years, scientific research on children and adolescents identified the major conditions influencing each of these problems.
Each of the chapters in this volume provides a concise summary of what is known about one of these five problem behaviors. Each chapter covers the following essential points:

- Incidence, prevalence, and cost of the problem, vital for gauging the importance of preventing the problem and for making the case for such efforts in public discussion of priorities;
- Biological and environmental influences which increase or decrease the likelihood of these problems; and,
- Principles, programs and policies that have been shown to reduce the incidence of each problem, information that can help in prevention of these behaviors.

Paediatric Clinical Pharmacology (Hardcover): Evelyne Jacqz-Aigrain, Imti Choonara Paediatric Clinical Pharmacology (Hardcover)
Evelyne Jacqz-Aigrain, Imti Choonara
R5,567 Discovery Miles 55 670 Ships in 10 - 15 working days

The treatment of children with medicinal products is an important scientific area. It is recognized that many medicines that are used extensively in pediatric patients are either unlicensed or off-label. This textbook will help pediatric health professionals select the most appropriate medication to effectively treat children and ensure minimal side effects.

Hematopoietic Cell Transplantation in Children with Cancer (Hardcover, 2014 ed.): Franklin O Smith, Gregory H. Reaman, Judy M.... Hematopoietic Cell Transplantation in Children with Cancer (Hardcover, 2014 ed.)
Franklin O Smith, Gregory H. Reaman, Judy M. Racadio
R4,769 Discovery Miles 47 690 Ships in 18 - 22 working days

This book is a comprehensive and up-to-date compendium on all aspects of blood and marrow transplantation in children. After an introductory chapter describing the history of pediatric blood and marrow transplantation, subsequent chapters discuss pediatric-specific aspects of transplantation, including stem cell sources suitable for transplantation, preparative regimens, graft-versus-host disease, complications related to transplantation, and late effects. The role of blood and marrow transplantation in various specific pediatric diseases is then examined, and the closing chapter considers future directions. The authors are all internationally recognized experts and offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of pediatric diseases that are treatable with blood and marrow transplantation and will prove invaluable to specialists, generalists, and trainees alike.

Behavioral Aspects of Pediatric Burns (Hardcover, 1994 ed.): Kenneth J. Tarnowski Behavioral Aspects of Pediatric Burns (Hardcover, 1994 ed.)
Kenneth J. Tarnowski
R2,813 Discovery Miles 28 130 Ships in 18 - 22 working days

In recent years, considerable professional attention has centered on the behavioral aspects of various childhood illnesses and injuries. Indeed, child health psychology has grown exponentially over the past decade. One index of this growth is found in the number of texts that have recently appeared in the area (Gross & Drabman, 1990; Karoly, 1988; Krasnegor, Arasteh, & Cataldo, 1986; Levine, Carey, Crocker, & Gross, 1982; Routh, 1988; Russo & Varni, 1982; Tuma, 1982; Varni, 1983). In general, these texts provide summaries of the psychological literature across a variety of established (e.g., oncology) and emerging (psychoneuroimmunology) areas of child health. Until recently, many books on the psychological aspects of pediatric health provided no or minimal information about the psychosocial plight of child burn victims. In some instances, pediatric burns might be men tioned parenthetically as another example of a population for which behavioral treatment procedures (e. g., pain management) may be of value. In part, the relative inattention devoted to this population may be related to the perception that the literature in this area is sketchy and charac terized by significant methodological and substantive shortcomings. In many instances, this perception is largely justified. However, it is also the case that the pediatric burn literature has evolved considerably over the past decade and that the incidence of, and morbidity associated, with severe burn injuries mandates immediate and increased attention by mental health professionals."

Community Child and Adolescent Psychiatry - A Manual of Clinical Practice and Consultation (Paperback, New): Theodore A. Petti,... Community Child and Adolescent Psychiatry - A Manual of Clinical Practice and Consultation (Paperback, New)
Theodore A. Petti, Carlos Salguero
R1,296 Discovery Miles 12 960 Ships in 10 - 15 working days

Child psychiatrists and psychologists, clinical nurses, social workers, and other mental health practitioners working in the public sector& mdash;where limited funds, poverty, social environments, and bureaucracy add to the daily challenges& mdash;can now turn to "Community Child and Adolescent Psychiatry" for approaches and insights to make their work easier and more productive. Twenty chapters are divided into four main sections, where 31 seasoned clinicians and administrators detail the most useful tasks, strategies, and tactics for child and family-focused community mental health professionals: Multiple facets of public sector agency work with or consultation to community agencies from the major mental health disciplines employed in community settings, differentiating roles and responsibilities and detailing consultation phases, including pitfalls Basic community practice principles and issues commonly faced by public sector professionals, including particular types of agencies and differences between rural and urban practice Contemporary concerns about the impact of a managed care or cost-cutting environment on service delivery, including reimbursement, differentiating consultation from direct service, and the location of a system of care Descriptions of the setting or activity of each community agency, including the qualifications that allow the professional or trainee to enter and work in that system Practicalities of clinical practice or consultation or both in community settings in the current service environment Questions& mdash;from differing perspectives& mdash;that mental health care practitioners must consider before consulting to or assuming a staff or administrativeposition in a community agency, different types of demands& mdash;and discussion of/for each role

Managed care has forever altered the service system landscape of mental health care in both the private and public sectors. "Community Child and Adolescent Psychiatry" provides insight into the public system of care and the requisite tools to manage the rapidly changing clinical, political, and administrative landscape.

As a resource guide to the profession, "Community Child and Adolescent Psychiatry" emphasizes the practical necessities of child psychiatrists and other professionals working with mentally ill youngsters and their families in the practice of community psychiatry and public mental health. Trainees, practitioners, and administrators alike will welcome this indispensable road-map to a higher level of practice in community settings.

Sexuality - A Developmental Approach to Problems (Hardcover, 1995 ed.): Betty N. Gordon Sexuality - A Developmental Approach to Problems (Hardcover, 1995 ed.)
Betty N. Gordon; Foreword by William N. Friedrich; Carolyn S. Schroeder
R1,499 Discovery Miles 14 990 Ships in 18 - 22 working days

There are few things that stir up our culture more than sex, particularly sex and children. Sexual behavior in children represents, to far too many people, further proof of the moral decay of our society. Any issue that provokes as strong an emotional reaction as childhood sexuality is obviously in need of a rational discussion. The best features of thought and reason include their moderating influence on overheated and reaction emotions. Consequently, this book by Betty Gordon and Carolyn Schroeder represents a very important, and even brave, counter to irrationality. When the Surgeon General of the United States is forced to resign because the words "children" and "masturbation" appear in the same sentence, you know that there is a great deal of misunderstanding about sexuality. My own evolution as a researcher in the area of child sexual abuse is a model of how naivete can be corrected by knowledge. Some of my early research in sexual abuse of children led me to realize that sexual behavior was a reliable marker of victimization in a relatively large percentage of children (Friedrich, Urquiza, & Beilke, 1986). My blinders to sexuality were evident in that I had not even hypothesized that to be the case in this early, exploratory research. When I realized how important sexual behavior was, several colleagues and I set out to interview parents and foster parents of sexually abused children more specifically. These adults were routinely quite reactive to our queries.

Effects of and Interventions for Childhood Trauma from Infancy Through Adolescence - Pain Unspeakable (Hardcover): Sandra... Effects of and Interventions for Childhood Trauma from Infancy Through Adolescence - Pain Unspeakable (Hardcover)
Sandra Hutchison
R5,198 Discovery Miles 51 980 Ships in 10 - 15 working days

Successfully reach out and help children through the worst times of their young lives! Effects of and Interventions for Childhood Trauma from Infancy Through Adolescence: Pain Unspeakable explores an array of trauma-related topics pertaining to children of all ages from a variety of cultures and countries. This book covers the various ego stages of child development and addresses how each one is affected by traumatic experiences. This easy-to-read resource serves as a readily available reference for caregiversprofessional or otherwisewho work with or encounter a child who has been traumatized. In Effects of and Interventions for Childhood Trauma from Infancy Through Adolescence, you'll find actual accounts of traumatic incidents throughout the world, focused specifically on those incidents that have the most devastating impact on large groups of children. This book reviews the research on post-traumatic stress disorder and stress-response related symptoms with brief descriptions of treatments for you to use with children who suffer from posttraumatic stress. Special features of this important tool consist of with an extensive list of organizations and crisis hotline numbers as well as recommended reading, video, and curricula resources. Effects of and Interventions for Childhood Trauma from Infancy Through Adolescence examines traumatic situations from many angles, including: the many faces of traumaaccidents, fire, natural disasters developmental considerations, including ego development, memory development, and the development of fears and responses the way children respond to traumatic incidents the types of interventionsindividual, group, family, pharmacological, and school-based cultural considerations from around the globe how to establish a school-based Trauma Response Team Effects of and Interventions for Childhood Trauma from Infancy Through Adolescence includes real case studies, fictional sample cases, and suggestions that walk you step-by-step through the possible scenarios that can occur with children during or after a traumatic event. Each section of the book ends with a helpful summary highlighting the most important information.

Fluid and Electrolytes in Pediatrics - A Comprehensive Handbook (Hardcover, 2010): Leonard G. Feld, Frederick J. Kaskel Fluid and Electrolytes in Pediatrics - A Comprehensive Handbook (Hardcover, 2010)
Leonard G. Feld, Frederick J. Kaskel
R4,992 Discovery Miles 49 920 Ships in 18 - 22 working days

For more than a decade, there has been no resource to guide the practitioner, trainee or allied health professional in this important field of pediatrics. These disorders are addressed every day with children admitted to the neonatal intensive care unit, pediatric intensive care unit, inpatient units, day hospitals, surgical units (inpatient and ambulatory), emergency rooms or in the outpatient setting.

Fluid and Electrolytes in Pediatrics: A Comprehensive Handbook is a complete compendium of ready access information for pediatricians, family practitioners, residents, students and allied health professionals. The manual will be a "go to" source for tables or information on any aspect of fluid, electrolyte and acid-base metabolism for general pediatrics/ family practitioners/residents/medical students/nurses or the medical or surgical specialties.

In order to achieve the goal as the "THE" textbook in this discipline, each chapter of the book will be divided into the following areas: Definition and Pathophysiology, Symptoms, Diagnosis and Causes, Treatment and Representative Scenarios. Case presentations/problems (6-10) to illustrate the key points within the chapter. The scenarios will attempt to cover the most common problems that present in pediatrics.

This book will have unique information with extensive tables, lists, and algorithms that detail clinical features of the entire spectrum of water metabolism, disorders of electrolytes, and disturbances in acid-base homeostasis by age (infants/newborns, children and adolescents) that is not available in any other textbook.

Movement Sciences - Transfer of Knowledge into Pediatric Therapy Practice (Hardcover): Robert J Palisano Movement Sciences - Transfer of Knowledge into Pediatric Therapy Practice (Hardcover)
Robert J Palisano
R4,212 Discovery Miles 42 120 Ships in 10 - 15 working days

Discover new perspectives and recent research findings to apply to the children and families on your caseload With Movement Sciences: Transfer of Knowledge into Pediatric Therapy Practice, you will explore the motor control, learning, and development of children with movement disorders, allowing you to increase the effectiveness of intervention. This book provides cutting-edge information on motor disabilities in children such as cerebral palsy, Down syndrome, or Erb's palsy and how prehension, balance, and mobility are affected. Expert researchers and practitioners offer their findings and techniques for improving motor processes, using figures, tables, and extensive resources to help you create more effective pediatric rehabilitation programs. With this book, you will gain a better understanding of: motor control for posture and prehension the motor learning challenges of children with movement dysfunction predictors of standing balance in children with cerebral palsy the effect of environment setting on mobility methods of children with cerebral palsy the reliability of a clinical measure of muscle extensibility in preterm and full-term newborn infants Movement Sciences: Transfer of Knowledge into Pediatric Therapy Practice will help physical therapists, occupational therapists, and other health care professionals implement motor learning concepts safely and effectively. This book also delivers practical advice for achieving the best results with a younger population by utilizing interventions that address the needs of their clients. With this guide, you will be able to determine which approaches are acceptable to the children and families in your practice, and ensure the therapy is meaningful to their daily lives.

Movement Sciences - Transfer of Knowledge into Pediatric Therapy Practice (Paperback): Robert J Palisano Movement Sciences - Transfer of Knowledge into Pediatric Therapy Practice (Paperback)
Robert J Palisano
R1,857 Discovery Miles 18 570 Ships in 10 - 15 working days

Discover new perspectives and recent research findings to apply to the children and families on your caseload With Movement Sciences: Transfer of Knowledge into Pediatric Therapy Practice, you will explore the motor control, learning, and development of children with movement disorders, allowing you to increase the effectiveness of intervention. This book provides cutting-edge information on motor disabilities in children such as cerebral palsy, Down syndrome, or Erb's palsy and how prehension, balance, and mobility are affected. Expert researchers and practitioners offer their findings and techniques for improving motor processes, using figures, tables, and extensive resources to help you create more effective pediatric rehabilitation programs. With this book, you will gain a better understanding of: motor control for posture and prehension the motor learning challenges of children with movement dysfunction predictors of standing balance in children with cerebral palsy the effect of environment setting on mobility methods of children with cerebral palsy the reliability of a clinical measure of muscle extensibility in preterm and full-term newborn infants Movement Sciences: Transfer of Knowledge into Pediatric Therapy Practice will help physical therapists, occupational therapists, and other health care professionals implement motor learning concepts safely and effectively. This book also delivers practical advice for achieving the best results with a younger population by utilizing interventions that address the needs of their clients. With this guide, you will be able to determine which approaches are acceptable to the children and families in your practice, and ensure the therapy is meaningful to their daily lives.

Protein Expression in Down Syndrome Brain (Hardcover, 2001 ed.): G. Lubec Protein Expression in Down Syndrome Brain (Hardcover, 2001 ed.)
G. Lubec
R5,300 Discovery Miles 53 000 Ships in 18 - 22 working days

When we worked on Down Syndrome brain in the past we have been focus ing on adult brain. This was a major step forwards as most work on Down Syndrome was carried out on fibroblasts or other tissues and, moreover, we introduced proteomics to identify and quantify brain protein expression. We considered evaluation of brain protein expression in Down Syndrome brain by and by more important than gene hunting at the nucleic acid level realiz ing the long unpredictable way from RNA to protein. The availability of fetal samples along with the proteomic appproach stimulated and reinforced studies on Down Syndrome brain. And indeed, it was found out that some observations on aberrant protein expression in adult Down Syndrome brain could not be verified in the fetal samples indi cating that neurodegeneration in adult Down Syndrome brain may have been responsible rather than trisomy 21. Using brains from the early second trimester of gestation led to the generation of a series of clues for the under standing of aberrant wiring of the brain in Down Syndrome and enabled the determination of altered key functions in early life; e. g. undetectably low drebrin was observed in Down Syndrome cortex, an integral constituent and marker for dendritic spines, main effectors of cross-talk between neurons. In addition, evaluation of the nature of the neuronal deficits in terms of neuro transmission markers could be established as well as neuronal density in fetal Down Syndrome cortex."

Developmental Language Disorders - From Phenotypes to Etiologies (Hardcover): Mabel L. Rice, Steven F. Warren Developmental Language Disorders - From Phenotypes to Etiologies (Hardcover)
Mabel L. Rice, Steven F. Warren
R4,218 Discovery Miles 42 180 Ships in 10 - 15 working days

Developmental Language Disorders: From Phenotypes to Etiologies is based on the recent conference of the same name sponsored by the Merrill Advanced Studies Center of the University of Kansas. In the past 10 years, considerable advances have taken place in our understanding of genetic and environmental influences on language disorders in children. Significant research in behavioral phenotypes, associated neurocortical processes, and the genetics of language disorders has laid the foundation for further breakthroughs in understanding the reasons for overlapping etiologies, as well as the unique aspects of some phenotypes. Too often the findings are disseminated in a fragmented way because of the discrete diagnostic categories of affectedness. This volume attempts to assimilate and integrate the findings of the transdisciplinary research toward a more coherent picture of behavioral descriptions, brain imaging studies, genetics, and intervention technologies in language impairment. The contributing authors are all scholars with active programs of research funded by the National Institutes of Health involving diverse clinical groups of children with language impairments.

Preschool Issues in Autism (Hardcover, 1993 ed.): Eric Schopler, Mary E. Van Bourgondien, Marie M. Bristol Preschool Issues in Autism (Hardcover, 1993 ed.)
Eric Schopler, Mary E. Van Bourgondien, Marie M. Bristol
R2,812 Discovery Miles 28 120 Ships in 18 - 22 working days

Drawing on the TEACCH program's twenty years of experience in clinical services, education, and research, this volume synthesizes some of the most important theory and data related to the early identification and intervention in autism and related disorders. Chapters addressing clinical aspects, parental concerns, and legal issues will be useful in helping professionals understand and implement state-of-the-art services for young children and their families.

Psychological Trauma and the Developing Brain - Neurologically Based Interventions for Troubled Children (Hardcover): Phyllis... Psychological Trauma and the Developing Brain - Neurologically Based Interventions for Troubled Children (Hardcover)
Phyllis Stien, Joshua C. Kendall
R2,049 Discovery Miles 20 490 Ships in 10 - 15 working days

Explore interventions and treatment methods designed to help curb the alarming trend toward violence in today's youth! Written in jargon-free lucid prose, Psychological Trauma and the Developing Brain: Neurologically Based Interventions for Troubled Children specifically shows how positive early experiences enhance brain development and how traumatic life experiences, especially child abuse and neglect, can affect a child's brain and behavior. Through carefully selected case studies, the book offers basic principles of treatment and a broad range of interventions that target the multiple symptoms and problems seen in children with a history of childhood trauma. Offering a new psychobiological model of child development, this book incorporates the influence of both genes and the environment and conceptualizes normal and pathological development in terms of common underlying processes. For readers concerned with promoting healthy development in children and helping children recover from childhood trauma, this engagingly written book describes exactly how a child's social/interpersonal environment can positively or negatively influence brain development. Throughout the book, the authors highlight the interrelationship between neurobiology and psychology. They present basic information about brain development and organization, describe exactly what is going on inside the brain at each stage of development, and illustrate these concepts through a detailed case study of a preschooler with severe problems in communicating and relating. They discuss the pernicious effects that traumatic stress has on brain and behavior, differentiating between simple and complex PTSD, and review the specific brain impairments currently attributed to a childhood history of maltreatment. Using their unique psychobiological perspective and illustrative case studies, the authors evaluate the principles and strategies of treatment, showing how relationships and experiences can mitigate the effects childhood trauma. After fleshing out the shocking cost to society of child maltreatment, the authors offer broad policy prescriptions that promote healthy development, including basic strategies for prevention and early intervention. Psychological Trauma and the Developing Brain: Neurologically Based Interventions for Troubled Children will show you: how interpersonal experience shapes brain development what is going on in the brain during the critical first six years how therapeutic relationships and interpersonal experience can promote emotional and cognitive development how childhood maltreatment can damage the brain and impair the developing mind what types of experiences and therapeutic strategies can mitigate the effects of childhood trauma what policy prescriptions, programs, and early intervention strategies can be implemented to promote healthy development

Longitudinal Studies of Children at Psychological Risk - Cross-National Perspectives (Hardcover, New): Charles W. Greenbaum,... Longitudinal Studies of Children at Psychological Risk - Cross-National Perspectives (Hardcover, New)
Charles W. Greenbaum, Judith G. Auerbach
R2,577 Discovery Miles 25 770 Ships in 18 - 22 working days
A Paediatric Vade-Mecum, 14Ed (Paperback, 14th edition): Timothy G. Barrett, A. Lander A Paediatric Vade-Mecum, 14Ed (Paperback, 14th edition)
Timothy G. Barrett, A. Lander
R1,490 Discovery Miles 14 900 Ships in 10 - 15 working days

A complete revision of the successful pocketbook, the fourteenth edition of A Pediatric Vade-Mecum will continue to provide, students and pediatric residents with invaluable information on the diagnosis and management of illness in children. Thoroughly revised and updated throughout and with a new editorial and author team, it will provide the trainee with practical evidence-based advice for the safe and effective management of the sick child. Retaining the easy-to-digest style that has made previous editions so popular, the content has been restructured into five major sections: acute pediatric problems, outpatient pediatrics, formulary, normal values and glossary of terms, with entries in sections 1 and 2 organized alphabetically for ease of reference.
Key Features:
* Covers immediate management of common emergencies and pediatric conditions supplemented with useful background information
* Provides evidence-based treatment guidelines and information on conditions not always covered by local departmental protocols
* Based on the needs of doctors in training
* Includes useful pediatric formulary based upon Medicines for Children for rapid reference
* Enhanced in this new edition by the inclusion of a helpful 'Glossary of terms'

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