Despite approximately 50 years of progress in the management of com plex congenital heart disease, hypoplastic left heart syndrome (HLHS) has been one of the last cardiac malformations to yield to effective surgical treat ment. The surgical therapies for hypoplastic left heart syndrome have evolved by two quite disparate routes. One approach has been the staged reconstruc tion operations utilizing an initial operation pioneered by many but developed by Dr. William Norwood and subsequently modified by many other investigators. The first stage reconstruction operation has been refined and standardized such that the majority of infants now proceed to second and third stage reconstruc tive operations culminating in a Pontan Kreutzer single ventricle physiology. An alternative surgical approach has been the development of neonatal and infant heart transplantation for HLHS. This approach also has had a signifi cant impact on the treatment of HLHS and other cardiac malformations and has been associated with good intermediate term results. Both of the thera peutic approaches devised for treatment of hypoplastic left heart syndrome have been effective and the outcomes are continuing to improve with each."

Transforming Residential Interventions: Practical Strategies and Future Directions captures the emerging changes, exciting innovations, and creative policies and practices informing ground-breaking residential programs. Building on the successful 2014 publication Residential Interventions for Children, Adolescents, and Families, this follow-up volume provides a contemporary framework to address the needs of young people and their families, alongside practical strategies that can be implemented at the program, community, system, and policy levels. Using the Building Bridges Initiative as a foundation, the book serves as a "how-to manual" for making bold changes to residential interventions. The reader will learn from a range of inspired leaders who, rather than riding the wave of change, jumped in and created the wave by truly listening to and partnering with their youth, families, advocates, and staff. Chapters provide real-time practice examples and specific strategies that are transformational and consider critical areas, such as family and youth voice, choice and roles, partnerships, permanency and equity, diversity, and inclusion. These methods benefit youth with behavioral and/or emotional challenges and their families and will improve an organization's long-term outcomes and fiscal bottom line. This book is for oversight agencies, managed care companies, providers of service, advocates, and youth/family leaders looking for an exemplar guide to the new frontier of residential intervention. In this era of accountability and measurement, it will become a trusted companion in leading residential interventions to improved practices and outcomes.

Until the 1990s, it was generally accepted that medicines were first developed for adults and their use in children was investigated later, if at all. One of the main tasks of hospital pharmacies was the manufacturing of child-appropriate formulations in a more or less makeshift way. The first change came in 1997 with U.S. legislation that rewarded manufacturers to do voluntary pediatric research. Ten years later, the European Union passed legislation that required manufacturers to discuss all pediatric aspects, including formulations, with the regulatory authorities as a condition of starting the registration procedure. In consequence, manufacturers must now cover all age groups, including the youngest ones. So far, pediatric formulations were more a focus for academic researchers. Through the changed regulatory environment, there is now a sudden high commercial demand for age-appropriate formulations. This book begins by highlighting the anatomical, physiological and developmental differences between adults and children of different ages. It goes on to review the existing technologies and attempts to draw a roadmap to better, innovative formulations, in particular for oral administration. The regulatory, clinical, ethical and pharmaceutical framework is also addressed.

First published in 1983. Routledge is an imprint of Taylor & Francis, an informa company.

Medical care of the terminally ill is one of the most emotionally fraught and controversial issues before the public today. As medicine advances and technologies develop, end-of-life care becomes more individualized and uncertain, guided less by science and more by values and beliefs. The crux of the controversy is when to withhold or withdraw curative treatments--when is enough, enough?
Political debates rage about when treatment is no longer effective; difficult cases are contested in courts; and the media devour the most sensational aspects of end-of-life care. In all this excitement and controversy, what is sadly overlooked is the extreme pressure that care of the terminally ill puts on medical staff as they deal with patients and their families and make life-or-death decisions. That pressure--the psychological strain and continuing uncertainties--is magnified when the patients are children.
David Bearison looks at this controversial issue from the perspective of the medical staff caring for dying children. Not just doctors, but nurses and counselors as well. By capturing their stories--as no other book has, Bearison is able to move beyond broad, abstract ideas about end-of-life care to convey the situated contexts of such care, including the complications, disagreements, frustrations, confusions, and unexpected setbacks.
In addition to a discussion of questions surrounding whether to withhold or withdraw curative treatments, When Treatment Fails explores the crucial concerns of those medical practitioners who care for dying children: education and training, relation with one another, communicating with patients and families, and finally, coping and moving on.Ultimately, the threads connecting these themes are the great costs and rewards of this difficult work, and the lessons that can be drawn from the nitty-gritty experiences of medical practitioners who struggle to find the balance between trying to defeat death and trying to provide comfort.

First published in 1982. Routledge is an imprint of Taylor & Francis, an informa company.

Early Life Origins of Health and Disease is a new book which presents and discusses the many factors that may have impact on normal development. In a concise and readable manner, the authors consider both the proven and suggestive evidence that the high prevalence of hypertension, diabetes, obesity and, in some populations, kidney disease, may not be all due to genetics or adult environment alone. There is good evidence that stress and more subtle dietary deficiencies, as well as placental malfunction, may increase the risk that the offspring will develop these problems in later life. Finally, new and emerging evidence for other areas of human health and disease such a motor control and mental health is critically reviewed for the first time. The book is a 'must' for all scientists interested in researching these areas, as there is a critical evaluation of the methodology used and suggestions for the 'optimal' way in which to investigate these phenomena.

First published in 1980. Routledge is an imprint of Taylor & Francis, an informa company.

Topics presented include: the role of autorelaxation and mental imagery in developmental pediatrics; graduates of the neonatal intensive care unit; self-destructive behaviors in children and adolescents; office screening for communication disorders; child and adolescent depression; television's impa

Sensitive periods occur when unique experiences permanently influence brain development either by their presence or absence. This volume covers underlying brain systems and behaviors that are sculpted by the environment in humans and animals in a search for commonalities. The mechanisms involved, the importance of timing in the process, and factors that can change the brain are discussed in this exciting book. Different chapters examine how experience guides the development of cells, circuits, and function using vision, cortical circuits, and cognition as frameworks. Scientific evidence for effective preventative intervention approaches, including diet, exercise, and music, are included to find ways to maximize child and adolescent development. The adverse effects of early brain injury are also included. As sensitive periods are gaining importance in their application in the real-world, novel statistical approaches for human studies are presented and the importance of sensitive periods are covered by examining the juvenile justice system. The book has interdisciplinary appeal and scholars with an interest in brain resiliency or vulnerability will find it of particular interest.

This collection of pediatric clinical cases focus on multiple sclerosis, neuromyelitis optica, acute disseminated encephalomyelitis and mimics. Dedicated sections on diseases affecting the brain, brainstem, spinal cord and the optic nerve feature chapters that include the diagnostic work up, therapeutic management and case outcome. Typical and atypical presentations of various pediatric demyelinating diseases also emphasize therapy response and those that breakthrough on treatment. Filling a critical gap in the literature on inflammatory disorders of the central nervous system, all those that treat patients with these rare and challenging disorders will find this book extremely helpful for their daily clinical practice.

This book combines empirical support, clinical acumen, and practical recommendations in a comprehensive manner to examine creative augmentations to the robust cognitive behavioral therapy (CBT) model. It discusses augmentations that are supported by research and practice and are also clinical-friendly tools. Each chapter briefly summarizes research findings, offers parsimonious explanations of theoretical concepts and principles, presents vivid descriptions of therapeutic procedures, and describes rich case illustrations. The book addresses the use of humor in CBT with youth, playful applications of CBT, applications of improvisational theatre in CBT and integrating superheroes into CBT. Key areas of coverage include: Building stronger, more flexible, and enduring alliances with children and adolescents to improve treatment retention and impact. Using humor and irreverent communication in dialectical behavior therapy (DBT) to enhance outcomes with adolescents. Developing rapport between medical and psychosocial team members to alleviate stress during pediatric medical procedures and as an adjunct to therapeutic interventions. Cognitive behavioral play therapy (CBPT) with young children. Family-focused CBT for pediatric OCD (obsessive-compulsive disorder). Cognitive Behavioral Psychodrama Group Therapy (CBPGT) with youth. This unique and compelling volume is an authoritative resource for researchers, professors, clinicians, therapists and other professionals as well as graduate students in developmental psychology, pediatrics, social work, child and adolescent psychiatry, and nursing.

Pediatric Urology: Evidence for Optimal Patient Management provides pediatric urologists the information needed for state-of-the-art patient care. Chapters are organized around pertinent clinical questions within major areas of pediatric urology, answered using the best available data while also reporting areas for which there is poor evidence. The text includes randomized controlled trials and prospective observational studies, tables that summarize important studies, and figures that illustrate algorithms with best options for management and their expected results. With an easy to use format not found in other volumes, Pediatric Urology: Evidence for Optimal Patient Management is an indispensible and unique resource for experienced pediatric urologists, pediatric surgeons, general urologists with an interest in pediatric urology, as well as fellows and residents in training.

This book assists health care providers to understand the specific interplay of the roles and relationships currently forming the debates in pediatric clinical ethics. It builds on the fact that, unlike adult medical ethics, pediatric ethics begins within an acutely and powerfully experienced dynamic of patient-family-state-physician relationship. The book provides a unique perspective as it interacts with established approaches as well as recent developments in pediatric ethics theory, and then explores these developments further through cases. The book first focuses on setting the stage by introducing a theoretical framework and elaborating how pediatric ethics differ from non-pediatric ethics. It approaches different theoretical frameworks in a critical manner drawing on their strengths and weaknesses. It helps the reader in developing an ability to engage in ethical reasoning and moral deliberation in order to focus on the wellbeing of the child as the main participant in the ethical deliberation, as well as to be able to identify the child's moral claims. The second section of the book focuses on the practical application of these theoretical frameworks and discusses specific areas pertaining to decision-making. These are: the critically ill child, new and enduring ethical controversies, and social justice at large, the latter of which includes looking at the child's place in society, access to healthcare, social determinants of health, and vaccinations. With the dynamic changes and challenges pediatric care faces across the globe, as well as the changing face of new technologies, no professional working in the field of pediatrics can afford not to take due note of this resource.

Some engage in high-risk behaviors. Others need help with emotional skills. Many are affected by mental disorders. While every school has its share of students needing comprehensive mental health services, personnel struggle to address these needs effectively in an era of scarce resources and dwindling budgets. Preventive Mental Health at School gives school-based practitioners and researchers an accessible, nuanced guide to implementing and improving real-world proactive programs and replacing outmoded service models. Based firmly in systems thinking and an ecological-public health approach, the book outlines the skills needed for choosing evidence-based interventions that are appropriate for all students, and for coordinating prevention efforts among staff, educators, and administration. As schools become more and more diverse, school-based practitioners must become knowledgeable in regard to the critical racial and cultural differences that affect students, their families, and enrich our schools. Research currently available to help meet the needs of various groups of children and their families is included as each topic is addressed. In addition, the author provides a theoretical groundwork and walks readers through the details of assessing resources and needs, applying knowledge to practice, and evaluating progress. Instructive case examples show these processes in action, and further chapters address questions of adapting programs already in place for greater developmental or cultural appropriateness. Included in the coverage: Student engagement, motivation, and active learning. Engaging families through school and family partnerships. Evidence-based prevention of internalizing disorders. Social emotional learning. Adapting programs for various racial and ethnic populations. Adapting programs for young children. Preventive Mental Health at School offers solid guidance and transformative tools to researchers, graduate students, and professionals/practitioners/clinicians in varied fields including clinical child and school psychology, social work, public health and policy, educational policy and politics, and pediatrics.

Master the principles and skills of respiratory care for neonates, infants, and children! Neonatal and Pediatric Respiratory Care, 6th Edition provides a solid foundation in the assessment and treatment of respiratory disorders in children. Clear, full-color coverage simplifies the concepts of respiratory care while emphasizing clinical application. Reflecting the changing face of this profession, this edition unpacks care strategies with coverage of the newest treatment algorithms, interventions, mechanical ventilation technologies, and more. From an expert team of contributors led by Brian K. Walsh, an experienced respiratory therapist and researcher, this text is an excellent study tool for the NBRC's Neonatal/Pediatric Specialty examination. Authoritative, evidence-based content covers all of the major topics of respiratory care for neonates, infants, and children, including both theory and application, with an emphasis on an entry-level BS degree. Nearly 500 full-color illustrations - plus clear tables and graphs - make it easier to understand key concepts. Case studies include a brief patient history and questions for each, showing how concepts apply to the more difficult areas of care for neonatal and pediatric disorders. Complete test preparation is provided through coverage of all the content in the matrix for the 2020 NBRC neonatal/pediatric specialty (NPS) credentialing exam. Learning Objectives at the beginning of each chapter break down key content into measurable behaviors, criteria, and conditions. Key Points at the end of each chapter summarize the more important information in a bulleted format. Assessment Questions at the end of each chapter are written in the NBRC multiple-choice style as found on the Neonatal/Pediatric Specialty (NPS) exam, helping you become familiar with the NBRC testing format. Glossary makes it easy to find definitions of all of the book's key terminology. Answers to assessment and case study questions are provided on the Evolve website. NEW! Logical, easy-to-use organization divides the content into three sections of 1) Neonatal, 2) Pediatrics, and 3) Neonatal and Pediatric combined, mirroring the academic approach of most respiratory care programs. NEW! Updated content reflects the new matrix for the 2020 NBRC Neonatal/Pediatric Specialty (NPS) exam. NEW! Assessment Questions at the end of each chapter are updated to reflect the changes to the 2020 NBRC exam. NEW! Additional treatment algorithms of care are added to relevant chapters.

The Formation of the Heart and its Regulation reviews in considerable detail the major events in heart development and their control via genes, cell-cell interactions, growth factors and other contributing elements. In addition, there is an extensive and useful overview of the field of heart development taken as a whole. The book will appeal to all students and researchers working on cardiovascular development and to pediatric cardiologists.

Written by the leading names in pediatric oncology and hematology, Nathan and Oski's Hematology and Oncology of Infancy and Childhood offers you the essential tools you need to overcome the unique challenges and complexities of childhood cancers and hematologic disorders. Meticulously updated, this exciting full-color, two-volume set brings together the pathophysiology of disease with detailed clinical guidance to provide you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children. Form a definitive diagnosis and create the best treatment plans possible with comprehensive coverage of all pediatric cancers, including less-common tumors, as well as all hematologic disorders, including newly recognized ones. Develop a thorough, understanding of the underlying science of diseases through summaries of relevant pathophysiology balanced with clear, practical clinical guidance. Nathan and Oski's is the only comprehensive product on the market that relates pathophysiology in such depth to hematologic and oncologic diseases affecting children. Quickly and effortlessly access the key information you need with the help of a consistent organization from chapter to chapter and from volume to volume. Stay at the forefront of your field thanks to new and revised chapters covering topics such as paroxysmal nocturnal hemoglobinuria, lysosomal storage diseases, childhood genetic predisposition to cancer, and oncology informatics. Learn about the latest breakthroughs in diagnosis and management, making this the most complete guide in pediatric hematology and oncology. Discover the latest in focused molecularly targeted therapies derived from the exponential growth of knowledge about basic biology and genetics underlying the field. Rely on it anytime, anywhere! Access the full text, images, and more at Expert Consult.

This book will enable practicing physicians and trainees to learn, in a clinically relevant and intellectually stimulating way, guidelines for appropriate ordering of imaging exams. The new edition provides more than 460 clinical case scenarios, organized into subspecialty modules (breast, cardiac, thoracic, gastrointestinal, urologic, women's, pediatric, vascular, musculoskeletal, and neurologic imaging). Each scenario is presented as a quiz in which the reader is invited to select the best option from various imaging modalities. All choices are given ratings of appropriateness and is consistent with the American College of Radiology (ACR) Appropriateness Criteria. Furthermore, a brief solution to each case is included. Finally, over 500 radiologic images are included each associated with a clinical case to illustrate the diagnostic capabilities of the imaging exam. This second edition incorporates new content and revisions to remain consistent with the updated ACR Appropriateness Criteria since the original publication in 2012. It will be an ideal tool both for self-study and for quantitative evaluation of students' knowledge.

"An extraordinary, eye-opening book." --People National Health Information Awards winner "A rousing wake-up call. . . . This highly engaging, provocative book prove[s] beyond a reasonable doubt that millions of lives depend on us finally coming to terms with the long-term consequences of childhood adversity and toxic stress." --Michelle Alexander, author of The New Jim Crow Dr. Nadine Burke Harris was already known as a crusading physician delivering targeted care to vulnerable children. But it was Diego--a boy who had stopped growing after a sexual assault--who galvanized her journey to uncover the connections between toxic stress and lifelong illnesses. The stunning news of Burke Harris's research is just how deeply our bodies can be imprinted by ACEs--adverse childhood experiences like abuse, neglect, parental addiction, mental illness, and divorce. Childhood adversity changes our biological systems, and lasts a lifetime. For anyone who has faced a difficult childhood, or who cares about the millions of children who do, the fascinating scientific insight and innovative, acclaimed health interventions in The Deepest Well represent vitally important hope for preventing lifelong illness for those we love and for generations to come?. "Nadine Burke Harris . . . offers a new set of tools, based in science, that can help each of us heal ourselves, our children, and our world."--Paul Tough, author of How Children Succeed "A powerful--even indispensable--frame to both understand and respond more effectively to our most serious social ills."--New York Times

A great deal is now known about neurofibromatosis type 1, particularly as a result of the identification of its causative gene by positional cloning. Effective treatments for its resulting cosmetic disfigurement, impaired cognitive performance and even life-threatening malignancy however sadly remain elusive.

As Dr Korf remarks in his Foreword; 'this book's cogent and thorough description of neurofibromatosis in children will take its place alongside other major clinical studies of the disorder. (Dr North) has tackled some of the more challenging issues, such as the basis for learning disabilities and the optimal means for early detection of optic gliomas. Her work provides a guide to the clinician and stands as a provocative challenge to the neurofibromatosis research community to further explore the basis of these problems.'
Unique account of the basis of learning disorder in this condition
Provides guidance on optimal methods for early detection of optic glioma
A thorough review of current knowledge of neurofibromatosis in childhood

This handbook synthesizes and integrates the science of internalizing and externalizing childhood disorders with the diagnostic structure of the Diagnostic and Statistical Manual - 5th Edition (DSM-5) of the American Psychiatric Association. It offers a comprehensive overview of DSM-5 disorders in childhood, covering etiology, symptom presentation, assessment methods, diagnostic criteria, and psychotherapeutic and pharmacological approaches to treatment, prognosis, and outcomes. Clinical vignettes and empirical insights illustrate key concepts and diagnostic and treatment issues such as developmental, cultural, gender, and other considerations that may influence diagnosis and case formulation. In addition, chapters on psychosocial therapies offer robust guidelines for working with children and adolescents with DSM-5 disorders. The Handbook also addresses the shift from categorical to dimensional, diagnostic, and treatment systems, particularly focusing on the current shift in funded research in childhood disorders. Topics featured in this Handbook include: Intellectual disabilities and global developmental delay. Depressive disorders in youth. Posttraumatic and acute stress disorders in childhood and adolescence. Autism spectrum and social pragmatic language disorders. Alcohol-related disorders and other substance abuse disorders. Parent-child and sibling relationships. Cognitive-behavioral interventions and their role in improving social skills. The Handbook of DSM-5 Disorders in Children and Adolescents is a must-have resource for researchers, professors, and graduate students as well as clinicians, professionals, and scientist-practitioners in clinical child and school psychology, pediatrics, social work, and educational psychology.

Although generally considered adult disorders, anxiety and depression are widespread among children and adolescents, affecting academic performance, social development, and long-term outcomes. They are also difficult to treat and, especially when they occur in tandem, tend to fly under the diagnostic radar.

"Anxiety and Depression in Children and Adolescents" offers a developmental psychology perspective for understanding and treating these complex disorders as they manifest in young people. Adding the school environment to well-known developmental contexts such as biology, genetics, social structures, and family, this significant volume provides a rich foundation for study and practice by analyzing the progression of pathology and the critical role of emotion regulation in anxiety disorders, depressive disorders, and in combination. Accurate diagnostic techniques, appropriate intervention methods, and empirically sound prevention strategies are given accessible, clinically relevant coverage. Illustrative case examples and an appendix of forms and checklists help make the book especially useful.

Featured in the text:

Developmental psychopathology of anxiety, anxiety disorders, depression, and mood disorders.

Differential diagnosis of the anxiety and depressive disorders.

Assessment measures for specific conditions.

Age-appropriate interventions for anxiety and depression, including CBT and pharmacotherapy.

Multitier school-based intervention and community programs.

Building resilience through prevention.

"Anxiety and Depression in Children and Adolescents" is an essential reference for practitioners, researchers, and graduate students in school and clinical child psychology, mental health and school counseling, family therapy, psychiatry, social work, and education.

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