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This book, the latest in the International Child Neurology Review series, is the first authoritative synthesis of the role of vitamin treatments in children with neurological disorders. It covers all the conditions seen in paediatric neurology that are treatable by vitamin supplementation and consists of up-to-date, concise reviews by an international group of experts in their specific fields. They cover: biotinidase deficiency; the role of vitamins in the developing nervous system, mitochondrial disorders and autism; homocysteinuria; conditions responsive to vitamin E or riboflavin; disorders of folic acid and vitamin B12 metabolism; folinic acid responsive seizures, and all aspects of pyridoxine-dependent and pyridoxine-responsive seizures. It is the first time that clinical and data research in this field has been drawn together in one source, making available previously unpublished material. This will be a unique data resource for anyone involved in the care of children with vitamin-responsive neurological disorders.

Over the last 20 years, pediatric otolaryngology has become a recognized subspecialty within otolaryngology head and neck surgery. Organizing the growth of clinical practice and knowledge in this area now is Pediatric Otolaryngology for the Clinician, a user-friendly resource for practicing general otolaryngologists, pediatricians and family practice physicians. This important title is divided into five sections: general ENT topics, otology, rhinology, head and neck disorders, and emergencies. Each chapter is authored by a recognized expert in the field and is concise and highly informative. Designed as a quick reference guide on a variety of topics such as antibiotic treatment of ear infections, sleep disorders in children, cochlear implantation, and airway management, to name just several, the book serves as a comprehensive yet succinct guide to caring for children with ear, nose and throat problems and will stand as an invaluable resource for any busy pediatric clinic.

Expanding Receptive and Expressive Skills through Stories (EXPRESS): Language Formulation in Children with Selective Mutism and Other Communication Needs is a resource that provides a specific treatment approach for professional speech-language pathologists working with children with selective mutism and other language delays or disorders including language learning disabilities, autism spectrum disorders, or for children learning English as a second language. It is a program for expanding receptive and expressive language skills at varying stages of language development, with five levels of communication to allow the clinician to start at the appropriate level for each child, and progress through the levels.The "EXPRESS" approach includes activity modules corresponding to classic children's stories. Children's literature is used as a tool for presenting activities designed to help children learn specific language skills, and supports the Common Core State Standards. Each of the modules requires the corresponding storybook that can be obtained individually or found within "The 20th Century Children's Book Treasury", a compendium that includes all the stories.Using "EXPRESS", children listen to the stories and through the activities presented acquire key concepts, ideas, and details about the material. Vocabulary is enhanced through drawing, describing, and demonstration. Children also have an opportunity to make inferences from the textual material through the question-answer routines developed for each story. Creativity and imagination are fostered using sentence formulation and story generation. "EXPRESS" also includes forms to help the clinician monitor progress and a PluralPlus companion website with video links to the stories and downloadable items from the book such as activity cards and scoring sheets.

Despite adults' best preventive efforts, childhood obesity is on the rise in most areas of the world, and with it the prevalence of Type 2 diabetes, hypertension, cardiovascular disease, and other formerly adult-onset conditions. Epidemiology of Obesity in Children and Adolescents takes the global ecological approach that is needed to understand the scope of the problem and its multiple causes and mechanisms, and to aid in developing more effective prevention and intervention programs. In the book's first half, experts present a descriptive summary of youth obesity trends in ten world regions, broken down by age group, gender, socioeconomic status, and risk factors. Complementing these findings, part two reviews the evidence base regarding the variables, separately and in combination, having the most significant impact on young people's development of obesity, including: * Genetic and nutrigenomic factors. * Environmental and psychosocial factors, such as family shopping and eating habits and access to healthful foods. * Neuroendocrine regulation. * Prenatal and neonatal factors (e.g., gestational diabetes of the mother). * Dietary factors, from nutrient content to young people's food preferences. * Physical activity versus sedentary behavior. Epidemiology of Obesity in Children and Adolescents is necessary reading for the range of professionals involved in curtailing this epidemic, including public health specialists, epidemiologists, pediatricians, nurses, nutritionists, psychologists, health educators, and policymakers.

Antisocial acts by children and teens are on the rise from verbal abuse to physical bullying to cyber-threats to weapons in schools. Strictly punitive responses to aggressive behaviour may even escalate a situation, leaving peers, parents, and teachers feeling helpless.

This unique volume conceptualizes aggression as a symptom of underlying behavioural and emotional problems and examines the psychology of perpetrators and the power dynamics that foster intentionally hurtful behaviour in young people. It details for readers how bibliotherapy offers relevant, innovative, and flexible treatment as a standalone intervention or as a preventive method in conjunction with other forms of treatment and can be implemented with individuals and groups, parents, teachers, and even rivals.

This unique, must-have resource is essential reading for school psychologists, school counselors, social workers, and clinical child psychologists and any allied educational and mental health professionals who work with troubled youth."

Movement disorder specialists, general neurologists, hepatologists, general gastroenterologists, and psychiatrists are the specialists who will most likely see some Wilson's disease patients during their careers. See them - yes. Recognize and diagnose them - maybe. If you are in one of these specialties, and a patient with tremor, hepatitis, cirrhosis, apparent Parkinsonism, or mood disorder, is referred to you, will you appropriately recognize the possibility that the underlying diagnosis may be Wilson's disease? Wilson's disease is both treatable and reversible, and commonly misdiagnosed. This book aims to change this with comprehensive coverage of every aspect of Wilson's disease, from well-catalogued, easy-to-use clinical diagnostic tools to treatment methods to molecular biology. Dr. Brewer is the world's leading expert on Wilson's disease, seeing and caring for over 300 patients with the disease during the last 20 years. He is a professor of human genetics at the University of Michigan.

This book focuses on precocious puberty, providing a unique continuum of expertise looking at puberty from anthropologic, epidemiologic, clinical, and molecular perspectives. The volume addresses broad pubertal changes in the general population while at the same time providing in depth information about specific disorders of puberty and the latest management changes. In particular, the book is intended for endocrinologists and internists.

This stimulating volume addresses vital questions about gene/environment interactions as they affect cell health from the prenatal period through later life. Beginning with a tour of epigenetic processes in the human body, the book assembles current theoretical and empirical developments across the discipline, among them transgenerational epigenetic inheritance, the effects of maternal nutrition on epigenetic change, and possible links between epigenetics and childhood obesity. Public health and policy aspects of the field are discussed in depth, with the understanding that much can be done to improve our epigenetic health as a species. And in this vein, contributors consider future possibilities, such as the reprogramming of genes to reverse cancer and other diseases. Included in the coverage: The role of environmental epigenetics in perinatal and neonatal development The epigenetic biomarker H2AX: from bench science to clinical trials What's the risk? Dental amalgam, mercury exposure, and human health risks throughout the lifespan Post-traumatic stress disorder: neurological, genetic, and epigenetic bases Children's exposure to alcohol, tobacco, and drugs: long-term outcomes Ethical implications of epigenetics Epigenetics, the Environment, and Children's Health Across Lifespans brings real-world knowledge and applications of this increasingly important field to public health practitioners, maternal and child health researchers, and environmental health experts.

This book offers a warning that American children are receiving increased chemical treatment from psychiatrists and provides a primer on how to improve the emotional health of kids without drugs. "Maelstrom" is an apt metaphor for the inexorable deterioration many children experience inside the mental health system. Kids Caught in the Psychiatric Maelstrom: How Pathological Labels and "Therapeutic" Drugs Hurt Children and Families challenges current treatment practices and addresses the critically important issue of excessive prescribing of psychiatric medications to children. This encyclopedic work reveals "inside the system" information, emphasizing the theoretical divide at the root of the controversy over diagnosis and treatment. It explains how the 1990s, "decade of the brain" replaced talk therapy with biochemical treatments, leading to the hegemony of the pharmaceutical industry—and subsequently the massive drugging of children. Author Elizabeth E. Root details common diagnoses and treatments, explaining up-to-date brain research, with some surprising interpretations, and noting dangerous national precedents to mental screening. Finally, she illuminates pathways toward solutions and healthier families, sharing nonpsychiatric explanations for the nation's increase of troubled children and the rationale and research supporting non-drug, alternative approaches to childhood distress.

Sleep disturbance is extremely common in the various disorders of development, be they physical or psychological in nature. It adds significantly to the burden of care but is a neglected topic and there is no single source of information to guide practice and management. In this book an international team of experts provides for the first time an integrated, comprehensive and up-to-date review of the nature and causes of sleep disorders, describing the special assessment and management considerations for each of the different developmental disorders. The book will be essential reading for all professionals working in the area of developmental disorders, and will also be of considerable interest to teachers, social workers and parents.

Reknowned authorities offer the first international handbook on anxiety and phobic disorders in children and adolescents. Using DSM-IV and ICD classifications, this comprehensive and up-to-date volume addresses issues related to diagnostic classification, epidemiolgy, etiology, assessment, and treatment. With its case studies, this volume makes a practical reference for clinicians, researchers, and students.

Course covers topics in infectious diseases in children and is intended for Pediatric Infectious disease trainees, trainers, and all those who manage children with infections.

This conference is being supported by several societies and is sponsored by several pharmaceutical companies, such as Aventis, Baxter, Chiron Vaccines, Wyeth, etc.

Hot Topics in Infection and Immunity in Children brings together leading experts in the field to provide a current and authoritative view concerning the hottest topics of concern to clinicians caring for children with infections and research scientists working in the areas of infectious disease, immunology, microbiology and public health. The book is based on a collection of manuscripts from a faculty of authors of international standing who contributed to a course in Paediatric Infection and Immunity in Oxford, UK in June 2003.

This book is Francoise Dolto s 1939 medical thesis and is dedicated to medical practitioners, paediatricians, and parents without prior knowledge of psychoanalysis. Francoise Dolto s aim was to sensitize people to the unconscious dimensions of many problems in children. She demonstrates here, through sixteen case studies, how often children s difficulties at school and at home be they behavioral or due to impaired learning abilities are the expression of psychological issues linked with their developing sexuality and castration anxiety, and result in physical symptoms such as enuresis and encopresis.Dolto points out that the awareness of the self and self-responsibility often develops for young people in families in which the parents do not know how to listen or even more importantly cannot be listened to with trust. There is also a summary of Freud s theories of the different stages of the evolution of the drives, as well as the central developmental role played by the castration complex, castration anxiety, and the Oedipus Complex."

Now in its second edition, Speech and Language Therapy: the decision-making process when working with children reveals how recent research and changes in health and education services have affected the decision-making process in the assessment and management of children with speech and language problems.

With individual chapters written by experts in their field, this book:

• Illustrates how the decisions made by practitioners may vary within different work settings
• Shows how these decisions may need to be adapted when working with specific client groups
• Explores how such decisions are part of effective evidence-based practice
• Offers an overview of the skills required by the developing professional
• Provides insight into working as a newly qualified therapist in the current job market.

Rigorously underpinned with current research and revised legislation, this is an important textbook for speech and language therapy students, potential students and specialist teachers in training. Speech and Language Therapy: the decision-making process when working with children will also be relevant to newly qualified therapists, therapists returning to the profession, specialist teachers and Special Educational Needs Coordinators.

This book provides a detailed and comprehensive overview of the role of diagnostic imaging in the assessment and management of trauma and polytrauma in children. The coverage includes imaging of injuries to the head, thorax, abdomen, bone and musculoskeletal system, with careful attention to the newest imaging techniques, imaging during the course of recovery and imaging of complications. A series of illustrative cases underline the prognostic value of imaging. In addition, an individual chapter is devoted to diagnostic imaging in cases of child abuse. The book concludes by discussing informed consent and medicolegal issues related to the imaging of pediatric traumatic emergencies. "Imaging Trauma and Polytrauma in Pediatric Patients "will be invaluable in enabling radiologists and clinicians to identify the main features and signs of injuries on a wide range of imaging techniques, including X-ray, ultrasonography, computed tomography and magnetic resonance imaging.

Dyslipidemias: Pathophysiology, Evaluation and Management provides a wealth of general and detailed guidelines for the clinical evaluation and management of lipid disorders in adults and children. Covering the full range of common through rare lipid disorders, this timely resource offers targeted, practical information for all clinicians who care for patients with dyslipidemias, including general internists, pediatric and adult endocrinologists, pediatricians, lipidologists, cardiologists, internists, and geneticists. For the last twenty years, there has been a growing recognition worldwide of the importance of managing dyslipidemia for the primary and secondary prevention of atherosclerotic vascular disease, especially coronary heart disease. This has been mainly due to the publication of the guidelines of National Cholesterol Education Program's Adult Treatment Panel and Pediatric Panel from the United States. These guidelines have stimulated generation of similar recommendations from all over the world, particularly Europe, Canada, Australia and Asia. Developed by a renowned group of leading international experts, the book offers state-of-the-art chapters that are peer-reviewed and represent a comprehensive assessment of the field. A major addition to the literature, Dyslipidemias: Pathophysiology, Evaluation and Management is a gold-standard level reference for all clinicians who are challenged to provide the best care and new opportunities for patients with dyslipidemias.

This volume provides a thorough overview of the Wilms' Tumour Gene (WT1). The book begins with three review chapters that cover the involvement of WT1 in pediatric cancer, kidney disease, and tissue development and homeostasis. The next few chapters discuss cell marking and lineage tracing, epicardial cell methodology, colony forming assays for bone marrow stem cells, angiogenesis assays and zebrafish tools. The next group of chapters explores the latest tools in genomics, molecular biology, and biochemistry. They discuss dissecting transcription factor function in cell free systems, ChiP seq, proteomics, RNA interactome, and multiphoton imaging of lipids, measuring the binding constants of protein-nucleic acid interactions, and bioinformatics approaches for analyzing Next Generation Sequence data. The final chapter discusses protocols for clinical trials for immune therapy using anti-WT1 peptides. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and thorough, The Wilms' Tumour (WT1) Gene: Methods and Protocols is a valuable resource for anyone who is interested in the diverse methodologies used in WT1 research.