This issue highlights some of the exciting new developments in pediatric oncology and hematology.? Three articles are devoted to pediatric leukemia, which remains the most common form of pediatric cancer.? Specifically, articles address ALL, AML, and leukemia in patients with Down syndrome. Other articles that address pediatric oncology include CNS tumors and neuroblastoma as well as advances in cancer immunotherapy. A very interesting article addresses the challenges experienced by adults who survived a childhood cancer. The hematology articles in this issue cover aspects that most clinicians see on a regular basis-sickle cell disease, thalassemia, and hemophilia, and ITP.

Since Dr. Kolon's issue on this topic published in 2004, there have been many updates in the diagnosis and treatment of urologic diseases in the pediatric population.? This issue provides updates in the following areas: management of complex pediatric disorders, disorders of sex development, treatment and management of urinary tract infections, and management of pediatric stone disease.? Emphasis is also given to laparoscopic and robotic approach to genitourinary anomalies in children, radiologic imaging in the genitourinary tract, and pediatric urologic oncology.

Sect 1 General Topics Sect 2 Cardiac Lesion Specific Postoperative Management Sect 3 Common Complications Sect 4 Miscellaneous Topics

Articles in this issue include: Adolescent Accessory Navicular; Flexible Pes Planus; Residual Clubfoot Deformity in Children; Gastroc/Soleus Contractures and Toe Walking; Late Sequelae of Childhood Clubfoot Treatment; Tarsal Coalitions; Update on the Treatment of Idiopathic Clubfoot and the Implications for the Adolescent and Adult Foot and Ankle; The Use of Gait Analysis in the Treatment of Pediatric Foot and Ankle Disorders; Ilizarov External Fixation in the Correction of Severe Pediatric Foot and Ankle Deformities; Subtalar Athroerisis in Pediatric Flatfoot Reconstruction.

In the past two decades we have seen a surge forward in understanding the genetics and biochemistry underlying many pediatric orthopaedic disorders. A few projects have even progressed into the realm of clinical trials that are primarily aimed at controlling progressive disease. Meanwhile, genomic technology development has outpaced expectations and is enabling gene discovery for disorders that were previously intractable with traditional genetic methods. Included in this latter category are common disorders that display multigenic inheritance, sporadic disorders, and very rare conditions that are difficult to ascertain. Simultaneously, the study of pediatric orthopaedic disorders has been continuously refined and updated, highlighting a number of likely genetic conditions that are as yet unsolved. Molecular Genetics of Pediatric Orthopaedic Disorders updates researchers and clinicians of new developments of pediatric orthopaedic genetics. The chapters inform the audience on the revolution in new genomic methods and the impact this is having on potential study designs and the potential to discover genetic causes of many unsolved orthopaedic conditions. Recent examples have been included of pediatric orthopaedic conditions, both rare and common, that are being solved with these new methods. The book also educates pediatric orthopedic clinicians and geneticists on our understanding of the biology of "classic" genetic diseases that were derived from prior genetic studies. Chapters include biobanks and strategies for studying very rare disorders, genes and pathways causing primordial dwarfism, and notch signaling in congenital scoliosis, and more.

This issue of Pediatric Clinics, guest edited by Drs. Dilip Patel and Donald Greydanus, examines the topic of Adolescents and Sports. Authorities in the field have come together to pen articles on Pre-participation evaluation, Cardiovascular evaluation of young athletes, Medical conditions and sport participation, Management of the adolescent athlete with type 1 diabetes mellitus, Musculoskeletal conditions and sports participation, Stress fractures: Diagnosis and management, Computer-based neuropsychological evaluation of concussion, The female athlete, Doping: From drugs and supplements to genetics, Analgesics and anti-inflammatory medications in sports, Nutritional considerations for adolescent athletes, Resistance training guidelines for adolescents, Application of osteopathic manual medicine to treat sports injuries, and Physically and cognitively challenged athletes.

This comprehensive issue on Substance Abuse in youth begins with articles on epidemiological trends, genetic risk factors, neurobiology of substance use disorders, and race and gender associations, and then provides detailed reviews on prevention and various treatment methodologies.? Treatments discussed include individual and group interventions (motivational interviewing and cognitive behavioral therapy), contingency reinforcement, multidimentional family therapy, pharmacotherapy, and post-treatment aftercare.? Also reviewed in detail are substance use disorders and psychiatric comorbidity.? The issue then takes a close look at two emerging areas of concern in youth: gambling and internet occupation, and energy drink use. By all accounts, a must-read issue for psychiatrists everywhere.

In this second part of a two-part issue on Pediatric US, imaging of the body with ultrasound is reviewed.? Genitourinary system is covered by articles on urinary tract infections, renal cystic disease, and scrotal ultrasound.? Articles on ultrasound of the gastrointestinal tract in the young infant, the vomiting young infant, the acute abdomen, and liver masses make up the abdominal topics.? Lastly a review of new techniques for pediatric ultrasound is provided.

Family doctors, pediatricians and other professionals who deal with children are regularly consulted because of febrile children. During the past few years remarkable advances on this subject of fever have been made. Among others, this book covers: - Different types of fever with possible complications, - Hyperthermia and their management, - Management of fever with guidelines on antipyretics and their side effects, - Complimentary medicine and fever, - Differential diagnosis of fever, with problem-setting and solving as a case presentation. This reader-friendly reference on the disorders of body temperature in children covers the entire spectrum of subjects related to fever. It gives an overview of the best treatment options in order to achieve the best results.

Optimization of Outcomes for Children After Solid Organ Transplantation is reviewed in this issue of Pediatric Clinics, guest edited by Drs. Vicky Lee Ng and Sandy Feng. Authorities in the field have come together to pen articles addressing Renal, Liver, Heart, Lung, and Small Bowel Transplantation in Children; Immunosuppression Armamentarium in 2010: Mechanistic and Clinical Considerations; Tolerance: Is it achievable in Pediatric Solid Organ Transplantation?; Optimizing Growth, Rehabilitation, and Neurodevelopmental Outcomes in Children after Solid Organ Transplantation; Prevention and Treatment of Infectious Issues after Solid Organ Transplantation in Children; Post-Transplantation Lymphoproliferative Disease; Non-Immune Complications Post-Transplantation?; Health-Related Quality of Life after Pediatric Transplantation; Adolescence and Adherence Issues of the Pediatric Solid Organ Recipient; Transition of Care of the Pediatric Solid Organ Recipient to Adult Care Teams; And Most Commonly Asked Questions from Parents of Transplant Families.

The subject of Pediatric Bone Marrow Transplantation is reviewed in this issue of Pediatric Clinics. Guest Editors Drs. Max Coppes, Terry Fry, and Crystal Mackall have assembled a panel of experts who offer reviews on topics including Allogeneic BMT for leukemia, GVL in pediatric leukemia, Stem cell source and outcome following BMT in children, Acute GVHD in children, Chronic GVHD in children, BMT for Hemoglobinopathies, BMT for immunodeficiency, BMT for rheumatologic disorders and other benign diseases, Autologous and Allogeneic BMT for solid tumors, Late effects following BMT, Cell therapies/vaccines for malignancy and infections, BMT for metabolic disorders, BMT for bone marrow failure syndromes, and Immunotherapy in the context of SCT.

This issue of Anesthesiology Clinics covers the most cutting-edge topics in pediatric anesthesia that every practitioner must know to stay current in this changing field. Topics covered include new devices for difficult pediatric airway, the use of ultrasound in pediatric regional anesthesia, new concepts in treatment of pediatric traumatic brain injury, acute pain management, neurotoxicity of anesthetics in the developing brain, current thought on intraoperative awareness in children, current concepts on managing sepsis in children, the fontan patient, sedating the child with congenital heart disease, management of children with hemoglobinopathies, and current strategies for blood conservation in pediatric anesthesia.

Currently, there are two types of pediatric disorder books available: high level technical books geared toward pediatric specialists, and self-help books for parents. The technical books cover diagnosis and treatment, while the self-help books cover general problems, are single authored, and speak little to the research of any given disorder. This volume consists of focused articles from the authoritative "Encyclopedia of Infant and Early Childhood Development" that cover the research information on common disorders in age 0-3. Topics include those most typically occurring, making them of great interest to both specialists and nonspecialists. Disorders and dysfunction of a variety of types are discussed, whether cognitive, social, emotional, or physiological. Coverageincludesasthma, allergies, colic, bedwetting, diarrhea, genetic disorders, SIDS and learning disabilities, and provides an essential, affordable reference for researchers in developmental psychology, as well as allied health fields.
Written at a level for general understanding-allows for easy and quick grasp of information to both specialists and non specialists alike Covers disorders across many systems (neurological, immunological etc) providing quicker access to info that would normally be dispersed across a wide literature Written by research experts ensuring accuracy that is sometimes lacking in non-specialist books Covers disorders, dysfunctions, and abnormal development in one place saving time looking at multiple sources for these related items"

Topics will include: History, Etiology and Pathophysiology of the Pediatric Pes Planovalgus Deformity; Clinical Diagnosis and Assessment of the Pediatric Pes Planovalgus; Flexible Pediatric Pes Planovalgus: Conservative and Surgical Treatment Options;? Rigid Pediatric Pes Planovalgus: Conservative and Surgical Treatment Options; and Pediatric Metatarsus Adductus and Skewfoot Deformity.

Guest Editor Adre du Plessis addresses Neonatal Neurology in this issue of Clinics in Perinatology, a companion to his September 2009 issue on Fetal Neurology. Mechanisms and management of acute brain injury is reviewed, including articles on Systemic and cerebral transitional hemodynamics in premature infants, Hypoxic-ischemic brain injury in the term infant, Neuroprotection in the newborn infant, Intracranial hemorrhage in the premature and term newborn, Infection-inflammatory mechanisms of brain injury in the newborn, Neonatal stroke, and Neonatal seizures. Next, Neurodiagnostic advances for the newborn infant is explored, with articles covering, Advanced brain MRI techniques, Advances in Near Infrared Spectroscopy, and Bedside electrocortical monitoring. The issue closes with a section devoted to Longterm neurologic outcome: Mechanisms of dysfunction and recovery, with articles on Longterm outcome in premature infants, Mechanisms of Cerebral Plasticity, The longterm effects of neonatal seizures, Constraint-induced therapy: Plasticity in practice, and Neonatal brain injury and autistic spectrum disorders in survivors.

Health Issues in Indigenous Children is reviewed in this issue of Pediatric Clinics, guest edited by Drs. Anne B. Chang and Rosalyn Singleton. Authorities from around the world have come together to pen articles on Infant care, Immunization, Growth and nutrition (include anemia), Pneumonia and lower respiratory tract infections, Chronic respiratory disorders: asthma and bronchitis, Acute and chronic diarrhea, Glomerulonephritis (GN) and managing the risks of chronic renal disease, Acute and chronic ear disease, Acute rheumatic fever and rheumatic heart disease (RHD), Skin disorders including scabies and tinea infections, Diabetes and other endocrine disorders, Behavioral and mental health problems, Dental issues affecting health, Developmental delay, Injuries including child neglect and abuse, and Health policy and service delivery.

Articles include: MR Imaging of the Pediatric Bone Marrow; The growing skeleton: MR appearances of developing cartilage; Infectious and Inflammatory Disorders; MRI of Pediatric Trauma; MRI of Pediatric Arthritis; MR Imaging of Primary Bone Tumors and Tumor-like Conditions in Children; MR Imaging of soft tissue masses in children; The hip: MR imaging of uniquely pediatric disorders; The knee: MR imaging of uniquely pediatric disorders; The foot and ankle: MR imaging of uniquely pediatric disorders; MRI in Congenital and Acquired Disorders of the Pediatric Upper Extremity.

Topics: Foundations of Pediatrics; HIV; Type 2 Diabetes; Angioedema and Anaphylaxis; Meningococcemia; Novel Pulmonary Endpoints in Clinical Trials; Inflammatory Mediators in Human Milk; Probiotics and Clinical Disease; Nutrition for Preterm Infants; Genetics of Microcephaly; Access to Healthcare Issues; Intersex; Cutaneous Drug Eruptions; Proteomics; Anorexia Nervosa; Pharmacology Review

Emory University Pediatrician Roy Benaroch wrote this guide to help parents understand the most common childhood maladies and misbehaviors and know what the best options are for action. Himself the father of three, Benaroch shares the insights of a medically-trained parent, telling us what he would do if his own child developed each malady. The topics addressed range from abdominal pain, ear infections and vomiting to issues with eating, sleeping and toilet training. Benaroch includes the most recent research in each area and shares vignettes from his own practice and his own household. All parents have faced the frustration of seeing their child sick and not knowing whether to rush to the doctor, offer over-the-counter remedies, or do little and wait to see if the problem passes. So too we have all faced those times when our children seem well but will not cooperate with behaviors involving eating, sleeping, or other activities. Emory University Pediatrician Roy Benaroch wrote this guide to help parents understand the most common childhood maladies and misbehaviors, and know what the best options are for action. Himself the father of three, Benaroch shares the insights of a medically-trained parent, telling us what he would do if his own child developed each malady. The topics addressed range from abdominal pain, ear infections and vomiting to issues with eating, sleeping and toilet training. Benaroch includes the most recent research in each area, and shares vignettes from his own practice, and his own household. Known widely simply as Dr. Roy, he is also the author of How to Get the Best Healthcare for Your Child (Praeger, 2007).

This issue of Pediatric Clinics offers an update on Nutritional Deficiencies. Guest Editors Drs. Praveen Goday and Timothy Sentongo have assembled a panel of world-class experts who offer reviews on topics including Protein-energy malnutrition, Nutritional deficiencies in the developing world, Nutritional deficiencies in children on restricted diets, Nutritional deficiencies in obesity (including bariatric surgery), Nutritional deficiencies during normal growth, Nutritional deficiencies during critical illness, Nutritional deficiencies in preterm infants, Nutritional deficiencies in liver disease, Short bowel syndrome, Cystic fibrosis, Refeeding syndrome, and Therapies associated with nutrient deficiencies (Sulfasalazine, methotrexate, seizure medications, steroids).

It's always been said, "Children are not young adults," and the examination of a child needs to be conducted with emphasis on the physiologic differences in a growing child. Clinical Orthopedic Examination of a Child focuses on pediatric examination, a topic not much explored in the regular orthopedic texts. A child's difficulty in verbally expressing his symptoms needs to be kept in mind during the examination, thus the examining surgeon has to be very observant in picking up even minor details that could help in diagnosis. This book serves as an essential companion to orthopedic surgeons, general practitioners, and professionals as well as being a welcome addition in pediatric orthopedic clinics. Key Features Reviews an unexplored topic of Pediatric Orthopedic examination with comprehensive clarity Has an algorithmic approach with step-by-step descriptions, complete with illustrations Provides helpful tips and insights to orthopedic surgeons, professionals, and trainees for accurate diagnosis and treatment