Should the production and use of chlorine and all chlorinated organic compounds be halted, in view of their adverse effects on the environment and human health? Those in favour argue that certain chlorinated compounds (PCBs, DDT, CFCs, etc.) have large negative environmental effects. The use of chlorine in disinfectants leads to the production of chloroform, while bulk products (PVC) contribute to the production of chlorinated dibenzo-p-dioxins and dibenzofurans when they are burned. Those against argue that chlorine and many chlorinated compounds are essential in the control of human health (the prevention of disease transmitted through drinking water that has not been disinfected), and that chlorinated compounds are indispensable intermediates in many production processes, representing a vast economic value. But such discussions often ignore the fact that Nature contributes significantly to the production of chlorinated organic compounds. More than 1000 such compounds are known, and their contribution to the biogeochemical cycling of chlorine is underestimated. Chlorine is organically bound in large quantities to humic materials, and natural production mechanisms are known for low molecular weight compounds (methyl chloride, chloroform, chlorinated dibenzo-p-dioxins and dibenzofurans). The role of these compounds in the environment is largely unknown. Naturally-Produced Organohalogens gives a complete overview of the present state of knowledge on the subject, giving a much needed balance to the argument sketched out above.

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects - properties, synthesis, reactions, physiological and industrial significance - of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

Photosensitization of Porphyrins and Phthalocyanines covers the scentific background to porphyrins and phthalocyanines, and applications of the compounds, especially for the application for photosensitization. It also has a review of advances in research and applications in this field.

This volume of Modern Aspects contains seven chapters. The major topics covered in the first six chapters of this volume include fundamentals of solid state electrochemistry; kinetics of electrochemical hydrogen entry into metals and alloys; oxidation of organics; fuel cells; electrode kinetics of trace-anion catalysis; nano structural analysis. The last chapter is a corrected version of chapter four from Volume 35. Faisal M. AI-faqeer and Howard W. Pickering begin the first chapter by going back to 1864 and Cailletet who found that some hydrogen evolved and was absorbed by iron when it was immersed in dilute sulfuric acid. The absorption of hydrogen into metals and alloys can lead to catastrophic failures of structures. They discuss the kinetics of electrochemical hydrogen entry into metals and alloys. In chapter three, Clyde L. Briant reviews the electrochemistry, corrosion and hydrogen embrittlement of unalloyed titanium. He begins by reviewing the basic electrochemistry and general corrosion of titanium. He also discusses pitting and galvanostatic corrosion followed by a review of hydrogen embrittlement emphasizing the formation of hydrides and the effect of these on titanium's mechanical properties. Christos Comninellis and Gy6rgy F6ti discuss the oxidative electrochemical processes of organics in chapter three. They begin by defining direct and indirect electrochemical oxidation of organics. They introduce a model that allows them to distinguish between active (strong) and non-active (weak) anodes. Different classes of organic compounds are used for kinetic models of organic oxidation at active and non-active type anodes.

The consumption of petroleum has surged during the 20th century, at least partially because of the rise of the automobile industry. Today, fossil fuels such as coal, oil, and natural gas provide more than three quarters of the world's energy. Unfortunately, the growing demand for fossil fuel resources comes at a time of diminishing reserves of these nonrenewable resources. The worldwide reserves of oil are sufficient to supply energy and chemicals for only about another 40 years, causing widening concerns about rising oil prices. The use of biomass to produce energy is only one form of renewable energy that can be utilized to reduce the impact of energy production and use on the global environment. Biomass can be converted into three main products such as energy, biofuels and fine chemicals using a number of different processes. Today, it is a great challenge for researchers to find new environmentally benign methodology for biomass conversion, which are industrially profitable as well. This book focuses on the conversion of biomass to biofuels, bioenergy and fine chemicals with the interface of biotechnology, microbiology, chemistry and materials science. An international scientific authorship summarizes the state-of-the-art of the current research and gives an outlook on future developments.

G.HAINNAUX Departement Milieu et Activites Agricoles, Centre ORSTOM, 911 Avenue d' Agropolis, B.P. 5045, 34032 Montpellier Cedex , France. Solid state fermentation, popularly abbreviated as SSF, is currently investigated by many groups throughout the world. The study of this technique was largely neglected in the past in European and Western countries and there is now a high demand for SSF, meaning in food, environment, agricultural, phannaceutical and many other biotechnological applications. It gives me satisfaction to note that the importance of this technique was realised at my department way back in 1975 since then, our team has put concentrated efforts on developing this technique. xvii Foreword Advances in Solid State Fermentation Foreword M. PUYGRENIER Agropolis Valorisation, Avenue d' Agropolis, 34394 Montpellier Cedex 5, France. On the name of the Scientific Community, I would like to express the wish that this International Symposium on SSF should be successful. Solid State Fermentation is part of biotechnology research. It consists on seeding solid culture medium with bacteria or fungi (filamentous or higher) and on producing, in this medium (solid components and exudates) metabolites and high value products. In fact, this process is very old. In older industries such the food and agricultural, this technique has been extensively used. An example of this is the production of pork sausages and Roquefort cheese. Pharmaceutical industry could make extensive use of SSF in the production of secondary metabolites of many kinds and development in this direction is soon expected.

This volume is concerned with the use of over 16 million tonnes of oils and fats by the oleochemical industry worldwide. It provides an overview of oleochemicals at research and professional level, with an emphasis on their industrial production and applications. Approximately half of the chapters consider matters of relevance throughout the oleochemical industry, while the remainder deal with applications. Authors are drawn from industrial and academic laboratories around the world.

The book is directed at chemists and technologists working on the production and use of oleochemicals, analytical chemists and quality assurance personnel, and lipid chemists in academic research laboratories.

The first contribution reviews the occurrence of xanthine alkaloids in the plant kingdom and the elucidation of the caffeine biosynthesis pathway, providing details of the N-methyltransferases, belonging to the motif B' methyltransferase family which catalyze three steps in the four step pathway leading from xanthosine to caffeine. The second contribution in this book provides a background on the molecule and related compounds and update knowledge on the most recent advances in Iboga alkaloids. The third contribution presents a comprehensive analysis of frequently occurring errors with respect to 13C NMR spectroscopic data and proposes a straightforward protocol to eliminate a high percentage of the most obvious errors.

Revised and expanded for the second edition, this text details the principal concepts and developments in wood science, chemistry and technology. It includes new chapters on the chemical synthesis of cellulose and its technology, preservation of wood resources and the conservation of waterlogged wood.

A complete restructuring and updating of the classic 1982 Handbook of Chemical Property Estimation Methods (commonly known as "Lyman's Handbook"), the Handbook of Property Estimation Methods for Chemicals: Environmental and Health Sciences reviews and recommends practical methods for estimating environmentally important properties of organic chemicals. One of the most eagerly anticipated revisions in scientific publishing, the new Handbook includes both a foreword and a chapter by Dr. Lyman.
Written for convenient and frequent use, each chapter integrates recent developments while retaining the elements that made the first version a classic. As a reference tool, the New Edition is indispensable. It comprehensively reviews recent developments in chemical property estimation methods and focuses on the properties most critical to environmental fate assessment.

The focus of this singular work is to discuss the role and importance of bioorganic phase in food products-providing the first major reference source for researchers looking to understand all aspects of the isolation, extraction and application of this major element in natural foods. From the identifying features to its applications through biotechnology and nanobiotechnology, this book covers all of the important aspects of bioorganic phase and points to future uses and methods. With chapters focusing on phase extraction and application, food product synthesis and nanoparticle application, Bioorganic Phase in Natural Food: An Overview covers both conventional and non-conventional approaches for the extraction of bioorganic phase from various food sources. Toxicity studies in nanoparticles are presented, and the vital role played by bioorganic phase toward nanoparticles synthesis is outlined in full. For any researcher looking for complete coverage of all main aspects of bioorganic phase in foods, this work provides a comprehensive and well-researched view of this important subject. .

Environmental problems have become increasingly complex. The procedures for investigating these problems cross the traditional boundaries of organic and analytical chemistry, microbiology and biology. Organic Chemicals: An Environmental Perspective brings together the basic issues of chemical analysis, distribution, persistence, and ecotoxicology.
The author illustrates each point with specific examples and presents a mechanistic approach to microbial reactions. Extensive cross referencing between chapters provides cohesion and complete coverage of issues tangential to each topic. The new edition has been extensively revised, and contains a new appendix, a new chapter, plus further revised information throughout the book. In fact, it is a completely new book.
A major difficulty in environmental science is that much of the background is widely scattered in the specialized chemical, microbiological, and biological literature. The coverage of all these areas in a single volume, the coherence supplied by the cross references, and the extensive references to the original literature makes Organic Chemicals: An Environmental Perspective a unique resource.

Filled with practical applications and research, Biodegradation of Nitroaromatic Compounds and Explosives presents an international perspective on environmental contamination from explosives. It covers biodegradation strategies for DNT and a wide variety of other nitroaromatic compounds of environmental significance and makes the information accessible to practicing environmental and chemical engineers. Biodegradation of Nitroaromatic Compounds and Explosives gives you a synthesis of ongoing research and an appreciation of the remarkable range of biochemical strategies available for the transformation of nitroaromatic compounds. It provides a realistic assessment of the current and potential field applications of the various strategies.

Corinna Reisinger has developed a new organocatalytic asymmetric epoxidation of cyclic and acyclic , -unsaturated ketones. In this thesis, Corinna documents her methodology, using primary amine salts as catalysts, and hydrogen peroxide as an inexpensive and environmentally benign oxidant. She describes the unprecedented and powerful catalytic asymmetric hydro peroxi dation of , -enones, a process which produces optically active five-membered cyclic peroxyhemiketals in a single operation. She also proves the versatility and synthetic value of the cyclic peroxyhemiketals by converting them into highly enantioenriched acyclic and cyclic aldol products. Currently, these cyclic aldol products are inaccessible by any other synthetic means. Furthermore, cyclic peroxyhemiketals are precursors to optically active 1,2-dioxolanes which are of biological relevance. This work is a breakthrough in the field of asymmetric epoxidation chemistry and outlines the most efficient method in the literature for generating highly enantioselective cyclic epoxyketones known to date.

Respectably old radical chemistry which plays a rna jor role in life-processes, both desired (breathing, ...) and non-desired (in- flammatory diseases, ageing, ...) has been gaining new youth in the past decade. Modern spectroscopy and other physical methods, recent advances in computational methods as well as impressive and mechanistically well-understood syntheses have led to a number of spectacular deve- lopments in the field of radical chemistry. The impact of these achi- evements will reach far beyond the field of organic chemistry, for example into biology and medicine. New facts and concepts in this rapidly expanding field deserved discussion among a number of leading experts present at the Workshop both for the information and constructive criticism. This happened during a particular brainstorming session and some of the impressions and reflections exchanged are recorded in the Epilogue. Indeed the topic chosen seems to be quintessential for the whole radical chemistry understanding and exploiting (single and multiple) substituent effects on radicals. We had the honour to organise this Workshop because some years ago, in collaboration with L. Stella, we became involved in radical stabi- lising effects when both a donor and an acceptor (captor) groups are present on a C-radical. This leads to an enhanced stabilisation which we called the captodative effect and we have endeavoured the first extensi ve investigation of this effect on carbon centered radicals.

An eclectic mix of studies on chemical and electrochemical behaviour of membrane surfaces. The book looks at membranes - both organic and inorganic - from a host of different perspectives and in the context of many diverse disciplines. It explores the behaviours of both synthetic and biological membranes, employing physical, chemical and physiochemical perspectives, and blends state-of-the-art research of many disciplines into a coherent whole.

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects - properties, synthesis, reactions, physiological and industrial significance - of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

Most organic reactions have long been carried out in organic solvents without concern for their real necessity, reaction efficiency, and pollution problems. Very recently, we have found that most organic reactions can be carried out in the absence of a solvent, namely, in the solid state. In many cases, the solid-state reaction proceeds more easily and efficiently, and even more selectively than solution reaction. This shows that molecules move easily and selectively in the solid state. This finding changed the classical idea which suggests "molecules do not move and reactions do not occur in the solid state," and opened up a new research field for the study molecular dynamics in the solid state. The organic solid state reactions have many possibilities to be developed. For example, enantioselective reactions can easily be accomplished by carrying out the reaction in an inclusion complex crystal with an optically active host compound.

Catalytic reactions also proceed in the solid state. Moreover, the solid-state reactions are more economical and ecologically sound. In the future, pollution-free synthetic procedures in the solid state will become increasingly important, not only in chemical industries but also in university laboratories.

Transition Metal Catalyzed Carbonylation Reactions is a comprehensive monograph focusing on carbon monoxide usage. This book provides students and researchers in organic synthesis with a detailed discussion of carbonylation from the basics through to applications. The authors have structured the book around the types of reactions, based on the different nucleophiles involved. Scientists working in carbonylation or with carbon monoxide, as well as teachers of organic synthesis can use this book to become familiar with this important area of organic chemistry.

Following the first two volumes "Dendrimers" (TCC vol. 197) and "Dendrimers II" (TCC vol. 210), the third volume dealing with this topic is now appearing in print (the "tetralogy" on dendrimers will soon be completed with the fourth volume). The present volume comprises a collection of up-to-date reviews written by renowned pioneers of research in the dendrimer field, three of whom lectured at the 1. International Dendrimer Symposium (IDS-1 1999) in Frankfurt. A focus of this volume is the variety of material properties of soft and shape-persistent dendrimers. As its predecessors did, this volume breaks through the frontiers to neighboring disciplines and, in an interdisciplinary approach, addresses topics such as polydisperse, hyperbranched macromolecules (dendritic polymers), the analysis of shape and density by small-angle scattering techniques, finely dispersed metals (dendrimers as catalysts), and nanotechnology close to potential applications.

This book focuses on the different compounds (polyphenols, sterols, alkaloids terpenes) that arise from the secondary metabolism of plants and fungi and their importance for research and industry. These compounds have been the backbone and inspiration of various industries like the food, pharmaceutical and others to produce synthetic counterparts. Furthermore, many of these compounds are still widely used to carry out specific functions in all these industries. This book offers a compilation of different texts from world leading scientists in the areas of chemistry, biochemistry, plant science, biotechnology which compile information on each group of secondary metabolism compounds, and their most important applications in the food, pharmaceutical, cosmetic and textile industry. By showcasing the best uses of these compounds, the chemistry behind their production in plants and fungi, this book is a valuable resource and a "go to" artifact for various audiences. The new approach this book offers, by linking research and the application of these compounds, makes it interesting as an inspiration for new research or as a hallmark of what has been done in the secondary metabolism of plants and fungi in recent years. Although this book may be technical, it is also enjoyable as an integral reading experience due to a structured and integrated flow, from the origins of secondary metabolism in organisms, to the discovery of their effects, their high intensity research in recent years and translation into various industries. Beyond learning more on their chemistry, synthesis, metabolic pathway, readers will understand their importance to different research and industry.