This title includes a number of Open Access chapters. Microbiology is the study of microorganisms (or microbes), which include bacteria, viruses, fungi, parasites, and even prions. In short, microbiology refers to the study of life and organisms that are too small to be seen with the naked eye. Microorganisms are found in almost every habitat present in nature and are vital to humans and the environment. While some microbes are harmful, causing diseases that harm and kill people, animals, and plants, they are exploited by researchers. They have uses in food, water treatment, science and medicine, energy, warfare, and much more. This new book presents a collection of new research and studies covering advances in microbiology dealing with medicine, agriculture, and more.

Fungi are now at the forefront of research on mechanisms in gene silencing, biological rhythm, mating processes, biogenesis of intracellular organelles, adaptations to hostile habitats, structure of natural populations, and speciation. Because of their small genomes, fungi are being used in "systems biology" to understand the connections between genes, proteins, and metabolic and signaling pathways. The ease with which yeasts and fungi can be cultivated in simple nutritive media has also made these eukaryotic organisms the choice material for basic and applied research. Fungi: Experimental Methods in Biology, Second Edition presents the latest information on fungal biology generated through advances in genetics, molecular biology, and biochemistry. It gives an account of real experiments that have been carried out on the diverse lifestyles of these organisms. Following in the footsteps of its highly-praised predecessor, this book continues to be a comprehensive review of the state of our knowledge about how fungi function. Examining both unicellular and multicellular fungi, this accessible book covers: Special features of fungi Interaction of fungi with other organisms Use of fungi as sources of chemicals for human health and welfare Model fungi in research Gene manipulation Adaptations Natural populations Throughout, the book draws attention to unsolved questions and to the opportunities offered by the diversity of fungi. Written by a prominent mycologist, it provides an excellent introduction and reference for beginning researchers as well as for experienced professionals. What's New in This Edition: New chapters on spores' dormancy, germination, and uses; fungi as scavengers; and fungi as chemical factories All chapters substantially revised, updated, and rewritten, in particular The Hyphal Mode of Life, Fungi as Symbiotic Partners, and Fungi as Plant Pathogens New material on the use of yeast for functional analysis of genomes; the use of Neurospora in cytogenetics and genes controlling conidiation; and the identification of the clock gene A new glossary to reinforce important concepts

Fish and shrimp producing industries generate huge amounts of wastes in form of viscera, scales, waste water, etc. Applications of microorganisms and/or microbesbased products have contributed significantly in solving many of these problems associated with aquaculture and waste management. This book addresses strategies for control of bacterial infection in farmed aquatic organism products. It covers: spoilage of fresh fish, microorganisms and processed seafoods, microbiological safety and quality of processed shrimps and fish and molecular detection of seafood borne human pathogenic bacteria.

A ubiquitous tool in mathematical biology and chemical engineering, the chemostat often produces instabilities that pose safety hazards and adversely affect the optimization of bioreactive systems. Singularity theory and bifurcation diagrams together offer a useful framework for addressing these issues. Based on the authors' extensive work in this field, Dynamics of the Chemostat: A Bifurcation Theory Approach explores the use of bifurcation theory to analyze the static and dynamic behavior of the chemostat.

Introduction
The authors first survey the major work that has been carried out on the stability of continuous bioreactors. They next present the modeling approaches used for bioreactive systems, the different kinetic expressions for growth rates, and tools, such as multiplicity, bifurcation, and singularity theory, for analyzing nonlinear systems.

Application
The text moves on to the static and dynamic behavior of the basic unstructured model of the chemostat for constant and variable yield coefficients as well as in the presence of wall attachment. It then covers the dynamics of interacting species, including pure and simple microbial competition, biodegradation of mixed substrates, dynamics of plasmid-bearing and plasmid-free recombinant cultures, and dynamics of predator-prey interactions. The authors also examine dynamics of the chemostat with product formation for various growth models, provide examples of bifurcation theory for studying the operability and dynamics of continuous bioreactor models, and apply elementary concepts of bifurcation theory to analyze the dynamics of a periodically forced bioreactor.

Using singularity theory and bifurcation techniques, this book presents a cohesive mathematical framework for analyzing and modeling the macro- and microscopic interactions occurring in chemostats. The text includes models that describe the intracellular and operating elements of the bioreactive system. It also explains the mathematical theory behind the models.

Produced by microbes on a large scale, methane is an important alternative fuel as well as a potent greenhouse gas. This volume focuses on microbial methane metabolism, which is central to the global carbon cycle. Both methanotrophy and methanogenesis are covered in detail. Topics include isolation and classification of microorganisms, metagenomics approaches, biochemistry of key metabolic enzymes, gene regulation and genetic systems, and field measurements. The state of the art techniques described here will both guide researchers in specific pursuits and educate the wider scientific community about this exciting and rapidly developing field.

Topics include isolation and classification of microorganisms, metagenomics approaches, biochemistry of key metabolic enzymes, gene regulation and genetic systems and field measurements.

The state-of-the-art techniques described here will both guide researchers in specific pursuits and educate the wider scientific community about this exciting and rapidly developing field.

Microalgae are a diverse set of eukaryotic photosynthetic organisms with great potential for being used to produce various high-value molecules. Using synthetic biology to manipulate and control the metabolic processes of microalgae, scientists hope to find economical and sustainable alternatives for commercial production of high value biochemicals and other metabolites for diverse applications. Highlighting the immense potential of microalgae as a renewable and sustainable source of commercially important, high-value biomolecules, this book covers the recent advances in the resources, tools, and techniques used for genetic engineering of microalgae. Also discussed are the legislative challenges associated with genetically engineered microalgae, their derived products and their uses, as well as socio-economic and environmental acceptance. Written to be accessible to a wide audience, this book will be a useful reference to students and researchers from both academia and industry, as well as policy makers, for understanding the current status, trends and future possibilities of using microalgae for biotechnological applications.

This book aims to disseminate the most current research in applied microbiology presented at the III International Conference on Environmental, Industrial and Applied Microbiology (BioMicroWorld2009) held in Lisbon, Portugal, in December 2009.This volume offers an inviting exploration of microbiology from scientific and industrial research to consumer products in a compilation of more than 150 papers written by leading experts in the field, who afford critical insights into several topics, review current research and discuss future directions to stimulate further discussions. This book also serves as an update on the most important current microbial research, by providing a comprehensive overview of cutting-edge topics in a single volume, where readers can also gain insights into how microbiology can solve problems in everyday settings.Although largely intended for microbiologists interested in knowing the latest developments in agriculture, environmental, food, industrial, medical and pharmaceutical microbiology and microbial biotechnology, this book is also a great source of reference for scientists and researchers involved in advancements in applied microbiology.

Foodborne pathogens continue to cause major public health problems worldwide. These organisms are the leading causes of illness and death in less developed countries, killing approximately 1.8 million people annually. In developed countries, foodborne pathogens are responsible for millions of cases of infectious gastrointestinal diseases each year, costing billions of dollars in medical care and lost productivity. In addition, new foodborne diseases are likely to emerge driven by factors such as pathogen evolution, changes in agricultural and food manufacturing practices, and changes to the human host status. A third problem is that there are growing concerns that terrorists could use pathogens to contaminate food and water supplies in attempts to incapacitate thousands of people and disrupt economic growth. Fuelled by these concerns, research into the genomics, molecular biology, and microbiology of the most important foodborne pathogens has escalated to unprecedented levels in recent

Pollution has accompanied polar exploration since Captain John Davis' arrival on the Antarctic continent in 1821 and has become an unavoidable consequence of oil spills in our polar regions. Fortunately, many of the organisms indigenous to Polar ecosystems have the ability to degrade pollutants. It is this metabolic capacity that forms the basis for bioremediation as a potential treatment for the hydrocarbons that contaminate the pristine polar environments. The only book to cover the breadth of microbial ecology and diversity in polar regions with an emphasis on bioremediation, Polar Microbiology: The Ecology, Biodiversity, and Bioremediation Potential of Microorganisms in Extremely Cold Environments examines the diversity of polar microorganisms and their ability to degrade petroleum hydrocarbon contaminants in polar terrestrial and aquatic environments. Providing a unique perspective of these microorganisms in extremely cold temperatures, the book focuses on their taxonomy, physiology, biochemistry, population structure, bioremediation potential, and potential for biotechnology applications. Leading investigators in the field provide complete coverage of the microbiology relevant to the study of biodiversity and biodegradation of pollutants in the Arctic and Antarctic, including: Microbial extremophiles living in cold and subzero temperature environments Genetics and physiology of cold adaptation of microorganisms Biodegradative microbial consortia in a defined closed environment Molecular characterization of biodegradative microbial populations Molecular approaches to assess biodegradation of petroleum hydrocarbons Environmental impact of hydrocarbon contamination Microbial biodiversity across Antarctic deserts By bringing together the current state of scientific knowledge and research on microbial community structures in extremely cold temperatures, this thought provoking resource is the ideal starting point for

Bacterial Genomes provides an in-depth review of the latest research on the structure and stability of microbial genomes, and the techniques used to analyze and "fingerprint" them. Maps of a variety of microorganisms are featured, along with articles describing their construction and relevant features. Extensive tables summarizing the different types of techniques available to analyze the genomes of these microorganisms are also presented. Among those who will find this text most useful are genome researchers, microbiologists, molecular biologists, bacteriologists, infectious disease researchers, and molecular evolutionary biologists. Researchers and students working in the field of molecular evolution in general will also be interested in this book since microbes are such popular model systems.

The book presents a chronology of events of "B. tabaci" and geminiviruses, and an overview within the Caribbean and Latin America. The pathosystems involving "Tomato yellow leaf curl virus," "Cotton leaf curl virus" and the cassava mosaic viruses are discussed. Data is presented on amino acid concentrations influencing "B. tabaci" and thus serves the basis for holidic diets. The essential molecular techniques for "B. tabaci" identification and classification are included with factors to consider for appropriate applications; an essential working guide for graduate students and researchers in the molecular field. Excellent photos portray symptoms of geminivirus-infecting crops: tomato, cotton, cassava, legumes and cucurbits; an important guide for researchers and growers. The novel insecticides, their mode of action and specificity; emphasize the applications of these within IPM programs.

The structure of a food influences the way it is transformed during processing and digestion. This in turn has an impact on nutrient bioaccessibility (release) and digestibility, and subsequently on the physiological response and health of the individual who consumes that food. Although evidence exists on the health benefits associated with the inclusion of certain lipid-rich foods (e.g. nuts, dairy products and fish) in the diet, the mechanisms that explain the physiological effects and the long-term benefits are not well understood. Lipids in themselves have many beneficial health effects: they are a source of energy and essential fatty acids, they are structural components of cell membranes, they are required to solubilise fat soluble compounds, and they serve as precursors of hormones. In addition, the overall structure of the food containing the lipids plays a crucial role in determining health benefits, notably by influencing lipid bioaccessibility and digestibility. Bioaccessibility and digestibility of lipids from food uniquely focuses on the physico-chemical properties of lipids and lipid rich food, as well as the subsequent effects on human health. Chapters from experts in food digestion examine food structure at both the macro- and micro- levels, covering lipids from plant and animal food products. The editors have developed the book for dietitians, nutritionists, and food scientists. Clinicians and other health professionals, educators in nutrition, and others working in the food industry will also find the material relevant.

Geomicrobiology is a combination of geology and microbiology, and includes the study of interaction of microorganisms with their environment, such as in sedimentary rocks. This is a new and rapidly-developing field that has led in the past decade to a radically-revised view of the diversity and activity of microbial life on Earth. Geomicrobiology examines the role that microbes have played in the past and are currently playing in a number of fundamental geological processes. The present book is of great importance for researchers working in the field of microbiology, biotechnology, geology and environmental biotechnology. It can be a major reference book for students as well as researchers.

This book outlines the production of chitooligossacharides and their derivatives and discusses their main biological activities, biomedical applications and their role in disease prevention. Chitooligosaccharides are products of chitosan or chitin degradation, prepared by enzymatic or chemical hydrolysis of chitosan, and they consist mainly of N-acetyl glucosamine and glucosamine bonded with a glycosidic bond. Compared to chitin and chitosan, chitooligossacharides offer advantages for large-scale and commercial applications due to their solubility in water and lower molecular weight. Written by leading experts, this book is divided into four parts. The first part provides a general introduction to chitooligossacharides. The second part focuses on the bioproduction of chitooligossacharides through enzymatic synthesis and also covers physical and chemical methods of synthesis. The third part explores the major biological activities of chitooligosaccharides, including antioxidant, antimicrobial, anti-allergic, anti-inflammatory, anti-cancer and neuroprotective activities, and discusses the disease preventing mechanisms of chitooligosaccharides. In this section, readers will also find about the latest in vivo studies which support the use of chitooligosaccharides in the prevention and control of disease. The final part highlights important biomedical applications of chitooligosaccharides, including in tissue engineering, drug delivery and wound healing applications. It also includes the volume editor's perspective on the health and safety risks of chitooligosaccharides. Given its scope, this book is useful not only for researches in the field but also for students interested in biomaterials, pharmaceuticals, marine biotechnology, nutraceuticals and food science.

This volume provides a wide range of aspects related to mycoremediation, which can be applied for both basic and advanced multidisciplinary research. Chapters guide readers through screening of fungi, Polyaromatic Hydrocarbons (PAHs), textile dyes, pesticides, bioreactors, molecular methods, redictive Mycology and Proteomics approaches to select fungi, elucidating biological mechanisms, and fungal laccase enzyme-based biosensors for the detection of environmental contaminants. Authoritative and cutting-edge, Mycoremediation Protocols aims to be a practical guide on the functional properties of poorly known applications of fungi in order to find solutions for increasing environmental problems.

This book deals with the most widespread of root symbiosis, arbuscular mycorrhizas, an essential component of soil/plant systems occurring in the majority of plant species in natural agro-ecosystems. It is intended to aid the environmental researcher in finding relevant methods quickly, and as a general reference work it will well serve field ecologists, laboratory biologists and other workers in plant biology and soil microbiology. The volume contains the most recent advances in (I) the field of the development of biomolecular methods adapted to arbuscular mycorrhizal fungi; (II) the promotion of innovative ecological research which considers biodiversity, in order to better understand the impact of arbuscular mycorrhizas in sustainable agriculture and natural ecosystems; (III) elucidating the role of arbuscular mycorrhizas in plant development and root morphology; and (IV) defining the cellular and molecular basis of plant-fungus exchanges. An article concerning The European Bank of Glomales, an essential tool for efficient international and interdisciplinary collaboration, is also included.

The increased emphasis on food safety during the past two decades has decreased the emphasis on the loss of food through spoilage, particularly in developed co- tries where food is more abundant. In these countries spoilage is a commercial issue that affects the pro't or loss of producers and manufacturers. In lesser developed countries spoilage continues to be a major concern. The amount of food lost to spoilage is not known. As will be evident in this text, stability and the type of spoilage are in?uenced by the inherent properties of the food and many other factors. During the Second World War a major effort was given to developing the te- nologies needed to ship foods to different regions of the world without spoilage. The food was essential to the military and to populations in countries that could not provide for themselves. Since then, progress has been made in improved product formulations, processing, packaging, and distribution systems. New products have continued to evolve, but for many new perishable foods product stability continues to be a limiting factor. Many new products have failed to reach the marketplace because of spoilage issues.

Create your own compost and grow better plants. With breathtaking clarity, Compost Science for Gardeners demystifies composting practices and helps readers determine the best technique for their unique situation. This comprehensive science-based book is your key to building healthier soil and growing better plants. Using plain language and easy-to-follow instructions, this essential resource distills and blends the latest scientific research with the author's many decades of knowledge and experience into manageable form, debunking a host of common gardening myths along the way. Learn about: The role of composting in the ecological cycle Compostable materials to incorporate and those to avoid Browns and greens vs the carbon-to-nitrogen ratio The full range of composting methods, including cold and hot composting; composting in piles, bins, and tumblers; and pit and trench composting Keyhole gardening, food digesters, vermicomposting, bokashi, eco-enzyme fermentation, and more The relative merits and impact on the environment of each composting technique Using finished compost to improve soil health Anyone can compost. Whether you are a balcony or backyard gardener, market gardener, small-scale farmer, or homesteader, or even if you are simply looking for a way to keep organic matter out of the landfill, this book will show you how to do it simply, safely, and sensibly.

Microbial Biofilms: Omics Biology, Antimicrobials and Clinical Implications is a comprehensive survey of microbial biofilms and their role in human health and disease with contributions from world renowned experts in molecular microbiology, proteomics, genomics, metabolomics and infectious diseases. The book is intended to serve as a guide for students, as well as a reference for researchers, clinicians and industry professionals. The chapters cover bacterial and fungal microbiomes, and the latest omics techniques organized in a clear and up-to-date manner. One of the highlights of this book is the comprehensive information on "omics of microbial biofilms". The chapters dedicated to metagenomics, proteomics and metabolomics are designed to provide a simple and holistic review of the current knowledge and, the applications of these techniques in the field of microbial biofilms. In addition to introductory chapters on microbial biofilms and their clinical implications, subsequent chapters delve into oral biofilms, their composition, and metagenomic diversity. Thereafter, mechanisms of drug resistance in microbial biofilms are reviewed, as well as the proteomic and metabolomic characterization of this resistance. The book includes a comprehensive discussion of persister cells and host-microbial interactions on mucosal surfaces. Finally, the book concludes with a summary of novel therapeutic approaches for biofilms such as synbiotics and biogenics.

Apart from malaria, schistosomiasis is the most prevalent parasitic infection in the world. It affects more than 200 million people in 76 tropical and subtropical countries, causing great suffering and resulting in thousands of deaths. Written by world authorities, this book examines many aspects of the biology, pathology, and control of the schistosoma parasite. Ranging in topic from infection in Pharaonic Egypt, through DNA relationships and biological systems, to advances in development of vaccines against the parasite, this book is a comprehensive text written for researchers and medical professionals alike.

Heritage Science is emerging as a discipline that brings together chemists, physicists, microbiologists, conservation scientists, archaeologists and conservators. Its scope, precise boundaries and the interfaces between its component disciplines may be in a state of flux but, above all, its interdisciplinary nature offers understanding of the causes, control and protection of heritage from ever-present environmental challenges. In particular, the activities of microbes play a central part in shaping the natural world of our planet but this awesome power constitutes a serious threat to the integrity of our most precious art, heritage artefacts, monuments and cultural treasures. Heritage artefacts that have been recovered from water, or that exist near the sea in maritime conditions, pose special conservation problems due in main to the combined effect of microbial activities and physical/chemical assaults that the environment can offer. This book is a result of the invited and updated papers from HMS2005: Microbes, Monuments and Maritime Materials and forms a comprehensive volume that addresses key topical areas of heritage science and discusses the threats to a wide range of heritage materials and monuments by biological and chemical agents of decay. Key features of the book include: " Up-to-date summaries on the conservation of internationally-important artefacts and monuments " Clear outline of molecular techniques to identify microbes in environmental heritage samples " Wide range of case studies covering wood, stone, cave and cave paintings " Contributions presented as fully referenced research publications giving useful technical details and identification of areas for future study " Informs conservators about the threats from microbes to a range of materials " Extensive range of case studies of important world heritage artefacts and monuments as well as an overview of in situ preservation of historic ships " Provides background knowledge on the use and application of modern analytical techniques in conservation " Contains detailed information on molecular and synchrotron techniques to assist with identifying biological and chemical threats to heritage artefacts and monuments The book also provides up-to-date information on subjects covering the component field of heritage microbiology, molecular and chemical analytical techniques, and the mechanisms of degradation and deterioration of historic ships and buildings. The book details state-of-the-art techniques for the study of large and small heritage objects, and their conservation. Techniques cover the use of GIS image processing, molecular biological analysis of environmental samples including FISH, electrophoresis to remove corrosive ions and synchrotron radiation to detect chemicals present in artefacts. Several authors have developed their methods through involvement in international collaborative projects such as BIOBRUSH, BACPOLES and Save the Vasa. Extensive emphasis is placed on case studies and there is a valuable section on historic ships covering the preservation of HMS Victory, ss Great Britain, Vasa and the Mary Rose. This book provides an indispensable guide and reference source for those working in all areas of historical conservation, biodeterioration, microbiology and materials science.

This comprehensive study of poultry meat safety offers readers the most up-to-date information on food safety concerns in poultry meat production. Chapters address recent topics of interest such as organic poultry production, antimicrobial resistant pathogens in poultry, antibiotic usage in poultry production, and pre- and post- harvest approaches to improving poultry meat safety. The last couple of decades have observed a significant increase in poultry meat production in the US. However, poultry meat is a potential source of foodborne pathogens such as Salmonella, Campylobacter spp. and pathogenic Escherichia coli (APEC linked to human infections), leading to economic losses to the poultry industry and impacting public health. Advances in knowledge in microbiology, molecular biology, immunology and "omics" fields have intensified efforts to improve the microbiological safety of poultry by targeting virulence mechanisms of the pathogens, developing vaccines and improving gut health in chickens. Moreover, due to the emergence of multidrug resistance in poultry-borne pathogens, and growth of organic poultry production, there exists significant interest for developing natural strategies for controlling pathogens in chickens. This edited volume provides insight into these strategies and covers other material of interest to food microbiologists, public health personnel, and poultry scientists. Readers of various backgrounds will appreciate its incorporation of recent developments not covered in other publications on the subject.

This book offers an analytical look at the much debated risks and benefits of the newly developed COVID-19 mRNA-vaccines. As such, it is one of the first books to give a comprehensive overview of mRNA vaccines against COVID-19 and the only one that addresses this topic from a broad multidisciplinary background. It brings together insights from various underlying disciplines on the challenges of developing and evaluating the most suitable vaccines for mass vaccination programs enrolled throughout the world - focusing on safety and efficacy. This book should not be missing on the shelf of any biomedical researcher, epidemiologist, public health professional or clinical researcher interested in SARS-CoV2 or virology and vaccine development in general.

The roots of most plants are colonized by symbiotic fungi to form mycorrhiza, which play a critical role in the capture of nutrients from the soil and therefore in plant nutrition. "Mycorrhizal Symbiosis" is recognized as the definitive work in this area. Since the last edition was published there have been major advances in the field, particularly in the area of molecular biology, and the new edition has been fully revised and updated to incorporate these exciting new developments.
Over 50% new material
Includes expanded colour plate section
Covers all aspects of mycorrhiza
Presents new taxonomy
Discusses the impact of proteomics and genomics on research in this area

This book discusses the extremophiles explored for biosynthesis of nanoparticles. Nanotechnology is a widely emerging field involving interdisciplinary subjects such as biology, physics, chemistry and medicine. A wide variety of microorganisms, such as bacteria, fungi and algae are employed as biological agents for the synthesis of nanoparticles. Novel routes by which extremophiles can be employed to generate nanoparticles have yet to be discovered. The book is divided into 5 major chapters: (1) Major types of nanoparticles in nanotechnology (2) Diversity of microbes in the synthesis of nanoparticles (3) Extremophiles in nanoparticle biosynthesis (4) Applications of nanoparticles produced by extremophiles (5) Challenges and Future perspectives