'A brilliant book [that] shows a way out of the destructive trap of Anthropocentric arrogance.' Vandana Shiva, from the Foreword Biocivilisations is a fascinating, original and important exploration into how complex civilisations existed on Earth long before humans. What is life? This is arguably the most important question in all of science. Many scientists believe life can be reduced to ‘mechanistic’ factors, such as genes and information codes. Everything can be sequenced and explained. But in a world as rich and complex as this one, can such an assertion really be true? A growing army of scientists, philosophers and artists do not share this mechanistic vision for the science of life. The gene metaphor is not only too simplistic but also misleading. If there is a way to reduce life to a single principle, how does that principle acknowledge the creativity of life that turns both genetic and information determinism on their heads? Biocivilisations is a groundbreaking book exploring the mysteries of life and its deep uncertainty. Dr Predrag Slijep�ević turns anthropocentric scientific thinking on its head, showing how the humble bacteria created the equivalent of cities and connected them with information highways, bringing our planet to life three thousand million years ago. He explains how bacteria, amoebas, plants, insects, birds, whales, elephants and countless other species not only preceded human beings but also demonstrate elements of complex civilisation – communication, agriculture, science, art, medicine and more – that we associate with human achievement. More than 99.99 percent of life on Earth has existed without humanity, and life will continue without humans long into the future. Biocivilisations is an important rethinking of the current scientific paradigm. It challenges us to reconsider the limited scope and time-window of our current ‘scientific revolution’ and to fundamentally reimagine what we call ‘life on Earth’.

Japanese macaques (Macaca fuscata) have been studied by primatologists since 1948, and considerable knowledge of the primate has been accumulated to elucidate the adaptation of the species over time and to distinct environments in Japan. The Japanese macaque is especially suited to intragenera and interpopulation comparative studies of behavior, physiology, and morphology, and to socioecology studies in general. This book, the most comprehensive ever published in English on Japanese macaques, is replete with contributions by leading researchers in field primatology. Highlighted are topics of intraspecific variations in the ecology and behaviors of the macaque. Such variations provide evidence of the ecological determinants on this species' mating and social behaviors, along with evidence of cultural behavior. The book also addresses morphology, population genetics, recent habitat change, and conflicts with humans, and attests to the plasticity and complex adaptive system of macaque societies. The valuable information in this volume is recommended reading for researchers in primatology, anthropology, zoology, animal behavior, and conservation biology.

Nature helps... of course at first itself by developing measures that give bacteria, fungi, plants and animals a chance to be successful in their struggle for life. As a latecomer on Earth, Homo sapiens was gifted with some droplets of the divine spirit of recognition and thus became able to observe, to analyse and recombine skills of other living beings and to use them for his overwhelming career over the last 10,000 years.Of course fungi, plants, animals and even bacteria were primarily used by mankind as food or as lifestyle products such as beer, but soon it became clear that there was much more potential hidden in these organisms and that they could be used for other purposes, too. Extracts of plants and fungi were recognized as powerful remedies, as medicines, as insecticides or acarizides, as repellents against parasites or even as weapons, e.g. when poisonous compounds from frogs or plants were applied to arrowheads. Over the last 110 years the pharmaceutical industry has often simulated nature by analyzing complex organic substances taken from living organisms and then producing by synthesis absolutely pure compounds, which mostly consisted of only one single active substance. These products had the advantage of acting against precisely one target and thus produced fewer possible side effects than the complex plant extracts. However, the more serious side effect was that disease agents could develop resistances to pure medicinal products much more easily. Thus after 70 years of excellent prospects for chemotherapy, some dark clouds appeared and quickly gathered, so that several therapeutic remedies now no longer work. Therefore in many countries - especially in those where the pure chemotherapeutics are too expensive for the poor population - the cry "back to nature" is becoming louder and louder. This has led to an enormous increase of studies that again use natural extracts as remedies in the fight against diseases. The present book summarizes examples of promising aspects in a broad spectrum of applications and shows how extracts derived from bacteria, marine organisms, plants or even animals may help to treat infectious diseases, how such organisms may keep away parasites and pests from the bodies of plants or animals, including humans, and how they can be used directly to aid in diagnosis, promote wound healing and even to help catch criminals. These 15 chapters offer not only basic research on these different fields, but also show how useful and effective products can be developed from research.

There are several books on properties of chitin and associated biomolecules and their biochemical significance. However, the present volume deals with a wide variety of biogeochemical and organic geochemical aspects of this vital macromolecule written by leading authors and experts in the field. Each chapter is carefully peer reviewed and is an updated account of recent research in isotopic, nanostructural, biochemical, microstructural, geochemical, paleontological and experimental aspects of chitin formation, distribution and preservation in the environment and earth history.

Francis Willughby together with John Ray revolutionized the study of natural history. They were motivated by the new philosophy of the mid 1600s and transformed natural history in to a rigorous area of study. Because Ray lived longer and more of his writings have survived, his reputation subsequently eclipsed that of Willughby. Now, with access to previously unexplored archives and new discoveries we are able to provide a comprehensive evaluation of Francis Willughby's life and works. What emerges is a polymath, a true virtuoso, who made original and imaginative contributions to mathematics, chemistry, linguistics as well as natural history. We use Willughby's short life as a lens through which to view the entire process of seventeenth-century scientific endeavor. Contributors are Tim Birkhead, Isabelle Charmantier, David Cram, Meghan Doherty, Mark Greengrass, Daisy Hildyard, Dorothy Johnston, Sachiko Kusukawa, Brian Ogilvie, William Poole, Chris Preston, Anna Marie Roos, Richard Serjeantson, Paul J. Smith and Benjamin Wardhaugh.

This volume focuses on defining the unique attributes of using the zebrafish cancer model for discovering important pathways and potential drug targets for the treatment of human cancers. Using the zebrafish model, the volume explores oncogene and tumor suppressor discovery, chemical genetic approaches, genomics, epigenetics, cancer imaging, and cell transplantation. Contributed chapters come from the most prominent laboratories working in this field, which provides a unique perspective on zebrafish models from a wide spectrum of the research community. In addition, the book offers a detailed analysis of the most current research in the area for specific zebrafish cancer models, including T cell leukemia, rhabdomyosarcoma, liver and pancreatic cancer, melanoma, neuroblastoma, germ cell tumors, and malignant peripheral sheath tumors. A chapter is also dedicated to the development and utilization of other piscine models of cancer. The compilation of chapters in the volume culminates into a comprehensive and definitive text on zebrafish and cancer, providing a much needed resource on the powerful attributes of the zebrafish model system.

This volume of the series Handbook of Zoology deals with the anatomy of the gastrointestinal digestive tract - stomach, small intestine, caecum and colon - in all eutherian orders and suborders. It presents compilations of anatomical studies, as well as an extensive list of references, which makes widely dispersed literature accessible. Introductory sections to orders and suborders give notice to biology, taxonomy, biogeography and food of the respective taxon. It is a characteristic of this book that different sections of the post-oesophageal tract are discussed separately from each other. Informations on form and function of organs of digestion in eutherians are discussed under comparative-anatomical aspects. The variability and diversity of anatomical structures represents the basis of functional differentiations.

Fish sensory systems have been extensively studied not only because of a wide general interest in the behavioral and sensory physiology of this group, but also because fishes are well suited as biological models for studies of sensory systems. This volume describes how fish are able to perceive their physical and biological surroundings, and highlights some of the exciting developments in molecular biology of fish sensory systems. Volume 25 in the Fish Physiology series offers the only updated thorough examination of fish sensory systems at the molecular, cellular and systems levels.
* Offers a comprehensive account of the present state of science in this rapidly expanding and developing field
* New physiological techniques presented to enable examining responses at the cellular and system levels
* Discusses fish sensory systems and how they have adapted to the physiological challenges presented by an aquatic environment

Howler monkeys (genus Alouatta) comprise twelve species of leaf-eating New World monkeys that range from southern Mexico through northern Argentina. This genus is the most widespread of any New World primate taxa, and can be found to inhabit a range of forest types from undisturbed rainforest to severely anthropogenically impacted forest fragments. Although there have been many studies on individual species of howler monkeys, this book is the first comprehensive volume to place information on howler behavior and biology within a theoretical framework of ecological and social adaptability. This is the second of two volumes devoted to the genus Alouatta. This volume: * Examines behavioral and physiological mechanisms that enable howler monkeys to exploit highly disturbed and fragmented habitats * Presents models of howler monkey diet, social organization, and mating systems that can also inform researchers studying Old World colobines, apes, and other tropical mammals These goals are achieved in a collection of chapters written by a distinguished group of scientists on the feeding ecology, behavior, mating strategies, and management and conservation of howlers. This book also contains chapters on the howler microbiome, the concept of behavioral variability, sexual selection, and the role of primates in forest regeneration.