Erythropoietin, Volume 105, the latest release in the Vitamins and Hormones series first published in 1943, and the longest-running serial published by Academic Press, provides up-to-date information on crystal structures and basic structural studies on neurotrophins and their receptors, neurotrophin functions and the biological actions of neurotrophins related to clinical conditions and disease. Topics covered in this new volume include Erythropoietin Receptor Structural Domains, Analysis of the Asymmetry of Activated EPO Receptor Enables Designing Small Molecule Agonists, Endogenous Erythropoietin, Erythropoietin Receptor Signaling and Lipid Rafts, and Erythropoietin and Hypothalamic-Pituitary Axis. Each thoroughly reviewed volume focuses on a single molecule or disease that is related to vitamins or hormones, with the topic broadly interpreted to include related substances, such as transmitters, cytokines, growth factors and others. This volume documents the activities of this vital molecule, also describing the structure and function of erythropoietin and its receptor.

This book presents a revised history of early biogeography and investigates the split in taxonomic practice, between the classification of taxa and the classification of vegetation. It moves beyond the traditional belief that biogeography is born from a synthesis of Darwin and Wallace and focuses on the important pioneering work of earlier practitioners such as Zimmermann, Stromeyer, de Candolle and Humboldt. Tracing the academic history of biogeography over the decades and centuries, this book recounts the early schisms in phyto and zoogeography, the shedding of its bonds to taxonomy, its adoption of an ecological framework and its beginnings at the dawn of the 20th century. This book assesses the contributions of key figures such as Zimmermann, Humboldt and Wallace and reminds us of the forgotten influence of plant and animal geographers including Stromeyer, Prichard and de Candolle, whose early attempts at classifying animal and plant geography would inform later progress.< The Origins of Biogeography is a science historiography aimed at biogeographers, who have little access to a detailed history of the practices of early plant and animal geographers. This book will also reveal how biological classification has shaped 18th and 19th century plant and animal geography and why it is relevant to the 21st bio geographer.