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Books > Science & Mathematics > Biology, life sciences > Human biology & related topics

The Temptation to Forget - Racism, Anti-Semitism, Neo-Nazism (Hardcover, New): Franco Ferrarotti The Temptation to Forget - Racism, Anti-Semitism, Neo-Nazism (Hardcover, New)
Franco Ferrarotti
R2,244 Discovery Miles 22 440 Ships in 10 - 15 working days

We are nothing in an absolute sense. We are only what we have been-more exactly, what we remember we were. So begins the latest book by one of Europe's most influential modern sociologists, Franco Ferrarotti. In The Temptation to Forget, Ferrarotti examines how many in the waning years of the 20th century are attempting to forget or reinvent history to serve the purposes of ethnic, racial, or religious separation. Ferrarotti focuses on anti-Semitism and its re-emergence among the Skinheads of the 1980s to draw parallels to how the Holocaust has been reinterpreted/forgotten, and to analyze the implications of this for relations with other ethnic, racial, and religious minorities. Ethnic cleansing may be a new term, but, as Ferrarotti illustrates, it has a long heritage in thought and action. This book will make for provocative reading among professional sociologists and students of contemporary social issues.

Vanquishing Cancer - Winning the Fight of Your Life (Hardcover): Steven P Shepard Vanquishing Cancer - Winning the Fight of Your Life (Hardcover)
Steven P Shepard
R1,994 Discovery Miles 19 940 Ships in 12 - 17 working days
Sociobiology and Bioeconomics - The Theory of Evolution in Biological and Economic Theory (Hardcover, 1999 ed.): Peter Koslowski Sociobiology and Bioeconomics - The Theory of Evolution in Biological and Economic Theory (Hardcover, 1999 ed.)
Peter Koslowski
R4,545 Discovery Miles 45 450 Ships in 12 - 17 working days

The volume at hand publishes the proceedings of the conference "Develop mental Systems, Competition, and Cooperation in Sociobiology and Eco nomics," a "Studies in Economic Ethics and Philosophy (SEEP)-Conference" held at Marienrode Monastery, Hildesheim-Marienrode near Hannover, Ger many, on 24-28 April 1996. This "Studies in Economic Ethics and Philoso phy (SEEP)-Conference" was made possible by the support of the Stiftung Forschungsinstitut fUr Philosophie Hannover Foundation Hannover Insti tute of Philosophical Research. The editor wishes to thank his co-workers at the Forschungsinstitut fUr Philosophie Hannover for their assistance in organizing the conference at Ma rienrode and Anna Maria Hauk M. A. and Bettina Lohnert M. A. for their as sistance in preparing the computerized version of this book. A special word of gratitude is due the Stiftung Forschungsinstitut fOr Phi losophie Hannover whose financial support made the conference in 1996 pos sible. Hannover, September 1998 P. K. Contents Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . V Sociobiology, Theory of Evolution, and Bioeconomics Introduction PETER KOSLOWSKI . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Part I Neo-Darwinian Synthesis, Sociobiology, and the Economy of Nature Chapter 1 Darwinian Monism: The Economy of Nature MICHAEL T. GHISELIN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 Chapter 2 Coercion TIM CLUTION-BROCK and GEOFF A. PARKER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 Chapter 3 Does the Second Law of Thermodynamics Refute the Neo-Darwinian Synthesis? BRUCE H. WEBER and DAVID 1. DEPEW . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 CONTENTS Partll Natural Selection and Developmental Systems: Redrawing the Boundaries Between Genetic and Non-Genetic Factors of Evolution Chapter 4 Evolutionary and Developmental Formation: Politics of the Boundary SUSAN OyAMA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ."

Mass Spectrometry and Genomic Analysis (Hardcover, 2001 ed.): J. N. Housby Mass Spectrometry and Genomic Analysis (Hardcover, 2001 ed.)
J. N. Housby
R3,023 Discovery Miles 30 230 Ships in 10 - 15 working days

76 2. Short Oligonucleotide Mass Analysis 76 2. 1. Method Outline 76 2. 2. Design of PCR Primers and Fragments for Analysis 78 2. 3. Typical PCR Reaction Conditions 79 3. Electrospray Ionisation Mass Spectrometry 79 Formation of Ions 3. 1. 79 3. 2. Tandem Mass Spectrometry 79 3. 3. Typical ESI-MS Settings for SOMA 80 4. Purification Procedures 80 4. 1. Phenol/Chloroform Extraction and Ethanol Precipitation 80 4. 2. In-line HPLC Purification 81 5. Genotyping Using SOMA 81 5. 1. APC Genotyping in Human Subjects 81 5. 2. APC Genotyping in Min Mice 85 5. Mutation Detection Using SOMA 86 6. 1. Analysis of p53 Mutations in Liver Cancer Patients 86 6. 1. 1. p53 Mutations in Liver Tumours 87 6. 1. 2. p53 Mutations in Plasma Samples 88 7. Advantages and Disadvantages of SOMA 89 8. Future Perspectives 90 9. Acknowledgements 91 10. References 91 CHAPTER 7 WV. Bienvenut, M. Muller, PM. Palagi, E. Gasteiger, M. Heller, E. Jung, M. Giron, R. Gras, S. Gay, PA. Binz, G J. Hughes, JC. Sanchez, RD. Appel, DF. Hochstrasser Proteomics and Mass Spectrometry: Some Aspects and Recent Developments 1. Introduction to Proteomics 93 2. Protein Biochemical and Chemical Processing Followed by Mass Spectrometric Analysis 94 2. 1. 2-DE Gel Protein Separation 95 Protein Identification Using Peptide Mass Fingerprinting and Robots 96 2. 2. 2. 2. 1. MALDI-MS Analysis 98 2. 2. 2. MS/MS Analysis 102 Improvement of the Identification by Chemical Modification of Peptides 106 2. 2. 3."

Religion and the Formation of Taiwanese Identities (Hardcover): P. Katz, M. Rubenstein Religion and the Formation of Taiwanese Identities (Hardcover)
P. Katz, M. Rubenstein
R2,938 Discovery Miles 29 380 Ships in 10 - 15 working days

This volume examines the creation of forms of individual and group identity in Taiwan, the relationship between these forms of identity, and patterns of Taiwanese religion, politics, and culture. The contributors explore the Taiwanese sense of self, attempting to discern how Taiwanese identify themselves as individuals and as collectivities. Ranging from the local to the national level and within the larger Chinese cultural and religious universe, these essays explore the complex nature of identity/role and the processes of identity formation which have shaped Taiwan's multi-leveled past and its many faceted present.

Evolutionary Theory and Human Nature (Hardcover, 2001 ed.): Ron Vannelli Evolutionary Theory and Human Nature (Hardcover, 2001 ed.)
Ron Vannelli
R3,087 Discovery Miles 30 870 Ships in 10 - 15 working days

Evolutionary Theory and Human Nature is an original, highly theoretical work dealing with the transition from genes to behavior using general principles of evolution, especially those of sexual selection. It seeks to develop a seamless transition from genes to human motivations as bio-electric brain processes (emotional-cognitive processes), to human nature propensities (various constellations of emotional-cognitive forces, desires and fears) to species typical patterns of behavior. This work covers two often antagonistic fields: biology and the social sciences. It should be of strong interest to anthropologists, sociologists, sociobiologists, psychobiologists and psychologists who are interested in the question of human nature influences on social behavior.

Patients and Agents - Mental Illness, Modernity and Islam in Sylhet, Bangladesh (Hardcover, New): Alyson Callan Patients and Agents - Mental Illness, Modernity and Islam in Sylhet, Bangladesh (Hardcover, New)
Alyson Callan
R2,939 Discovery Miles 29 390 Ships in 12 - 17 working days

Sylhet, the area of Bangladesh most closely associated with overseas migration, has seen an increase in remittances sent home from abroad, introducing new inequalities. Social change has also been mediated by the global forces of Western biomedicine and orthodox Islam. This book examines the effects of these modernizing trends on mental health and on local, traditional healing as the new inequalities have exacerbated existing social tensions and led to increased vulnerability to mental illness. It is the young women of Sylhet who are most affected. The global economy has increased competition for resources and led to marriage being seen as a route to economic advancement. Parents prefer to give their daughters in marriage to families that will widen their social contacts and enhance their economic and social standing. Accordingly, the young wife's outsider status (and hence vulnerability to mental illness) has increased as it is no longer customary to give daughters in marriage to local kin. Yet, patients and their families do not work out tensions passively. They are active agents in the construction of their own diagnosis. The extent to which patients act or are acted upon is an investigation that runs throughout the book.

Alyson Callan is a psychiatrist and anthropologist. She currently works as a consultant psychiatrist in Brent for the Central and North West London NHS Foundation Trust.

Sociology of Oliver C. Cox - New Perspectives (Hardcover): Herbert Hunter Sociology of Oliver C. Cox - New Perspectives (Hardcover)
Herbert Hunter
R4,194 Discovery Miles 41 940 Ships in 12 - 17 working days

This work presents original and critical papers on the life and sociological contributions of Oliver C. Cox. The unique features of this volume include an analysis of Cox's enigmatic career as a sociologist, his links with Marx, Weber and Mills, his contributions to world system theory, and his legacy with and exclusion from the Chicago School.

Bone Loss and Osteoporosis - An Anthropological Perspective (Hardcover, 2003 ed.): Sabrina C. Agarwal, Samuel D. Stout Bone Loss and Osteoporosis - An Anthropological Perspective (Hardcover, 2003 ed.)
Sabrina C. Agarwal, Samuel D. Stout
R2,991 Discovery Miles 29 910 Ships in 10 - 15 working days

With the growing incidence of fragility fractures in Europe and North America over the last three decades, bone loss and osteoporosis have become active areas of research in skeletal biology. Bone loss is associated with aging in both sexes and is accelerated in women with the onset of menopause. However, bone loss is related to a suite of complex and often synergistically related factors including genetics, pathology, nutrition, mechani cal usage, and lifestyle. It is not surprising that its incidence and severity vary among populations. There has been increasing interest to investigate bone loss and osteoporosis from an anthropological perspective that utilizes a biocultural approach. Biocultural approaches recognize the inter-relationship between biological, cultural, and environmental variables. Anthropological studies also highlight the value of evolutionary and population approaches to the study of bone loss. These approaches are particularly suited to elucidate the multifactorial etiology of bone loss. The idea for this volume came out of a symposium organized by the editors at the 70th annual meeting of The American Association of Physical Anthropologists in Kansas City, Missouri. Many of the symposium participants, along with several additional leading scientists involved in bone and osteoporosis research, are brought together in this volume. Each chapter focuses on a different aspect of bone loss and fragility with a fresh and stimulating perspective."

Beyond Memory - The 1944 Deportation of the Crimean Tatars and Their Repatriation to Their Historical Homeland (Hardcover, 2004... Beyond Memory - The 1944 Deportation of the Crimean Tatars and Their Repatriation to Their Historical Homeland (Hardcover, 2004 Ed.)
Ann Laura Stoler
R2,927 Discovery Miles 29 270 Ships in 10 - 15 working days

In the early morning hours of May 18, 1944 the Russian army, under orders from Stalin, deported the entire Crimean Tatar population from their historical homeland. Given only fifteen minutes to gather their belongings, they were herded into cattle cars bound for Soviet Central Asia. Although the official Soviet record was cleansed of this affair and the name of their ethnic group was erased from all records and official documents, Crimean Tatars did not assimilate with other groups or disappear. This is an ethnographic study of the negotiation of social memory and the role this had in the growth of a national repatriation movement among the Crimean Tatars. It examines the recollections of the Crimean Tatars, the techniques by which they are produced and transmitted and the formation of a remarkably uniform social memory in light of their dispersion throughout Central Asia. Through the lens of social memory, the book covers not only the deportation and life in the diaspora but the process by which the children and grandchildren of the deportees returned and anchored themselves in the Crimean Peninsula, a place they had never visited.

Human Diet - Its Origin and Evolution (Hardcover): Peter S. Ungar, Mark F. Teaford Human Diet - Its Origin and Evolution (Hardcover)
Peter S. Ungar, Mark F. Teaford
R3,126 Discovery Miles 31 260 Ships in 10 - 15 working days

Diet is key to understanding the past, present, and future of our species. Much of human evolutionary success can be attributed to our ability to consume a wide range of foods. On the other hand, recent changes in the types of foods we eat may lie at the root of many of the health problems we face today. To deal with these problems, we must understand the evolution of the human diet.

Studies of traditional peoples, non-human primates, human fossil and archaeological remains, nutritional chemistry, and evolutionary medicine, to name just a few, all contribute to our understanding of the evolution of the human diet. Still, as analyses become more specialized, researchers become more narrowly focused and isolated. This volume attempts to bring together authors schooled in a variety of academic disciplines so that we might begin to build a more cohesive view of the evolution of the human diet. The book demonstrates how past diets are reconstructed using both direct analogies with living traditional peoples and non-human primates, and studies of the bones and teeth of fossils. An understanding of our ancestral diets reveals how health relates to nutrition, and conclusions can be drawn as to how we may alter our current diets to further our health.

Producing Speech: Contemporary Issues - for Katherine Safford Harris (Hardcover, 1995 ed.): Fredericka Bell-Berti, Raphael J.... Producing Speech: Contemporary Issues - for Katherine Safford Harris (Hardcover, 1995 ed.)
Fredericka Bell-Berti, Raphael J. Lawrence
R3,255 Discovery Miles 32 550 Ships in 12 - 17 working days

Market: Those interested in speech, especially speech production, and graduate students studying the anatomy and physiology of speech. Katherine Safford Harris is known throughout the speech research community for her contributions to our understanding of speech behaviors and her leadership at Haskins Laboratories. Her research has shown how the study of speech disorders can provide a window through which we can observe normal behaviors and learn much about the control systems of speech production. In recognition of this work, each section of this book contains chapters on normal speech production as well as speech disorders. These original contributed chapters cover a wide range of subjects, including respiratory patterns in normal speech, speech breathing processes in hearing-impaired persons, laryngeal adductory behaviors, spasmodic dysphonia, tongue shaping and vowel articulation, speech production in children with cochlear implants, and more.

Plants, Health and Healing - On the Interface of Ethnobotany and Medical Anthropology (Paperback): Elisabeth Hsu, Stephen Harris Plants, Health and Healing - On the Interface of Ethnobotany and Medical Anthropology (Paperback)
Elisabeth Hsu, Stephen Harris
R858 Discovery Miles 8 580 Ships in 12 - 17 working days

."..the book offers a platform to raise thought-provoking questions and encourages in-depth analyses to bridge the gulf between ethnobotany and medical anthropology...Highly recommended." Choice

"The tantalising and rather eclectic selection of edited chapters takes the reader around the world following plants making their way into local pharmacopoeias, symbolic systems, myths and ways of coping with the unknowns of human illness. This book offers a much needed, concise edited volume on plants, health and healing. It brings together research in the disciplines of botany, biochemistry, clinical medicine, anthropology and history highlighting the contributions of multidisciplinary research to promote a more nuanced understanding of medicinal plant use." JRAI

Plants have cultural histories, as their applications change over time and with place. Some plant species have affected human cultures in profound ways, such as the stimulants tea and coffee from the Old World, or coca and quinine from South America. Even though medicinal plants have always attracted considerable attention, there is surprisingly little research on the interface of ethnobotany and medical anthropology. This volume, which brings together (ethno-)botanists, medical anthropologists and a clinician, makes an important contribution towards filling this gap. It emphasises that plant knowledge arises situationally as an intrinsic part of social relationships, that herbs need to be enticed if not seduced by the healers who work with them, that herbal remedies are cultural artefacts, and that bioprospecting and medicinal plant discovery can be viewed as the epitome of a long history of borrowing, stealing and exchanging plants.

Elisabeth Hsu is Professor of Anthropology at the University of Oxford, where she has convened its master's courses in medical anthropology since 2001. Based on her earlier studies in biology (botany), linguistics and sinology, she has published widely on the history and anthropology of Chinese medicine.

Stephen Harris was awarded a Ph.D. in plant systematics from the University of St. Andrews in 1990. He has been the Druce Curator of Oxford University Herbaria since 1995 and has published over 50 peer-reviewed papers on genetics and systematics associated with the evolutionary consequences of plant-human interactions.

Neopterin - Biochemistry, Methods, Application (Hardcover, Reprint 2011): H. Wachter, Etc, D. Fuchs, A. Hausen Neopterin - Biochemistry, Methods, Application (Hardcover, Reprint 2011)
H. Wachter, Etc, D. Fuchs, A. Hausen
R4,387 Discovery Miles 43 870 Ships in 12 - 17 working days
Blueberries (Paperback): Ellena Savage Blueberries (Paperback)
Ellena Savage 1
R330 R275 Discovery Miles 2 750 Save R55 (17%) Ships in 9 - 15 working days

'I mean who cares about opinions, gossip, whatever, when bodies are so vulnerable, in search only of love and breath.' The body frequently escapes her, but is always very much present in these compellingly vivid, clear-eyed essays on an embodied self in flight through the world, from the brilliant young writer Ellena Savage. In Portuguese police stations and Portland college campuses, in suburban Melbourne libraries and wintry Berlin apartments, Savage shows bodies in pain and in love, bodies at work and at rest. She circles back to scenes of crimes or near-crimes, to lovers or near-lovers, to turn over the stones, re-read the paperwork, check the deeds, approach from another angle altogether. These essays traverse cities and spaces, bodies and histories, moving through forms and modes to find a closer kind of truth. Blueberries is ripe with acid, promise, and sweetness.

The Dominican Americans (Hardcover, illustrated edition): Ramona Hernandez, Silvio Torres-Saillant The Dominican Americans (Hardcover, illustrated edition)
Ramona Hernandez, Silvio Torres-Saillant
R2,043 Discovery Miles 20 430 Ships in 10 - 15 working days

This profile of Dominican Americans closes a critical gap in information about the accomplishments of one of the largest immigrant groups in the United States. Beginning with a look at the historical background and the roots of native Dominicans, this book then carries the reader through the age-old romance of U.S. and Dominican relations. With great detail and clarity, the authors explain why the Dominicans left their land and came to the United States. The book includes discussions of education, health issues, drugs and violence, the visual and performing arts, popular music, faith, food, gender, and race. Most important, this book assesses how Dominicans have adapted to America, and highlights their losses and gains. The work concludes with an evaluation of Dominicans' achievements since their arrival as a group three decades ago and shows how they envision their continued participation in American life. Biographical profiles of many notable Dominican Americans such as artists, sports greats, musicians, lawyers, novelists, actors, and activists, highlight the text.

The authors have created a novel book as they are the first to examine Dominicans as an ethnic minority in the United States and highlight the community's trials and tribulations as it faces the challenge of survival in a economically competitive, politically complex, and culturally diverse society. Students and interested readers will be engaged by the economic and political ties that have attached Americans to Dominicans and Dominicans to Americans for approximately 150 years. While massive immigration of Dominicans to the United States began in the 1960s, a history of previous contact between the two nations has enabled the development of Dominicans as a significant component of the U.S. population. Readers will also understand the political and economic causes of Dominican emigration and the active role the United States government had in stimulating Dominican immigration to the United States. This book traces the advances of Dominicans toward political empowerment and summarizes the cultural expressions, the survival strategies, and the overall adaptation of Dominicans to American life.

Social Bodies (Paperback): Helen Lambert, Maryon McDonald Social Bodies (Paperback)
Helen Lambert, Maryon McDonald
R736 Discovery Miles 7 360 Ships in 12 - 17 working days

A proliferation of press headlines, social science texts and "ethical" concerns about the social implications of recent developments in human genetics and biomedicine have created a sense that, at least in European and American contexts, both the way we treat the human body and our attitudes towards it have changed. This volume asks what really happens to social relations in the face of new types of transaction - such as organ donation, forensic identification and other new medical and reproductive technologies - that involve the use of corporeal material. Drawing on comparative insights into how human biological material is treated, it aims to consider how far human bodies and their components are themselves inherently "social." The case studies - ranging from animal-human transformations in Amazonia to forensic reconstruction in post-conflict Serbia and the treatment of Native American specimens in English museums - all underline that, without social relations, there are no bodies but only "human remains." The volume gives us new and striking ethnographic insights into bodies as sociality, as well as a potentially powerful analytical reconsideration of notions of embodiment. It makes a novel contribution, too, to "science and society" debates.

Principles of Human Evolution 2e (Paperback, 2nd Edition): R. Lewin Principles of Human Evolution 2e (Paperback, 2nd Edition)
R. Lewin
R1,876 R1,541 Discovery Miles 15 410 Save R335 (18%) Out of stock

"Principles of Human Evolution" presents an in-depth introduction to paleoanthropology and the study of human evolution. Focusing on the fundamentals of evolutionary theory and how these apply to ecological, molecular genetic, paleontological and archeological approaches to important questions in the field, this timely textbook will help students gain a perspective on human evolution in the context of modern biological thinking.

The second edition of this successful text features the addition of Robert Foley, a leading researcher in Human Evolutionary Studies, to the writing team. Strong emphasis on evolutionary theory, ecology and behavior and scores of new examples reflect the latest evolutionary theories and recent archaeological finds. More than a simple update, the new edition is organized by issue rather than chronology, integrating behavior, adaptation and anatomy. A new design and new figure references make this edition more accessible for students and instructors.
New author, Robert Foley - leading figure in Human Evolutionary Studies - joins the writing team.
Dedicated website - www.blackwellpublishing.com/lewin - provides study resources and artwork downloadable for Powerpoint presentations.
Beyond the Facts boxes - explore key scientific debates in greater depth.
Margin Comments - indicate the key points in each section.
Key Questions - review and test students' knowledge of central chapter concepts and help focus the way a student approaches reading the text.
New emphasis on ecological and behavioral evolution - in keeping with modern research.
Fully up to date with recent fossil finds and interpretations; integration of genetic and paleoanthropological approaches.

A Legal History of Asian Americans, 1790-1990 (Hardcover): Robert H. Hyung Chan Kim A Legal History of Asian Americans, 1790-1990 (Hardcover)
Robert H. Hyung Chan Kim
R2,813 Discovery Miles 28 130 Ships in 10 - 15 working days

This book describes the historical and legal experiences of Americans of Asian ancestry who began to come to the United States in the mid-19th century. Like all immigrants in America, they arrived with hopes of making a better life and home in a free country. Instead, Asian-Americans have been mistreated and discriminated against by their fellow Americans--even by Congress and the Supreme Court, which should have made and judged laws without prejudice. This study examines the way immigration and naturalization laws were unfairly administered against Asian immigrants and throws light on a less than admirable period of American legal history. It will be of great interest to scholars in Asian American studies, legal history, and American history.

A Guide to Ethnic Health Collections in the United States (Hardcover, New): Tyson Gibbs A Guide to Ethnic Health Collections in the United States (Hardcover, New)
Tyson Gibbs
R1,374 Discovery Miles 13 740 Ships in 10 - 15 working days

Ethnic minority groups in the United States suffer and die from disease at rates much higher than the general population. Such groups include African-Americans, Alaska Natives, Native Americans, Hispanics, and Pacific Asian Americans. To understand the nature of the deplorable rates, the health history of the ethnic groups must be understood. This book describes the contents of libraries nationwide which house health and medically related materials on ethnic minority populations. The book covers information about catalogs, books, articles, biographies, and autobiographies, primary source materials, cassette tapes of speeches, video tapes and films, and medical artifacts.

The repositories covered are in various stages of cataloguing these materials but indicate an interest in having researchers use the collections. This book is the most comprehensive guide to ethnic medical health materials, their location, state of completion, and the contents of collections.

Molecular and Cellular Mechanisms of Cardiovascular Regulation (Hardcover): Hasso 04Scholz, Masao Endoh, Toshihiko Iijima,... Molecular and Cellular Mechanisms of Cardiovascular Regulation (Hardcover)
Hasso 04Scholz, Masao Endoh, Toshihiko Iijima, Martin Morad, Hasso Scholz
R1,623 Discovery Miles 16 230 Ships in 10 - 15 working days

This volume contains selected papers presented at the Sendai International Sympo sium on Molecular and Cellular Mechanisms of Cardiovascular Regulation held from May 10-12, 1995, to honor the contributions ofProfessorNorio Taira, Chairman of the Department of Pharmacology (1972-1995), Tohoku University School of Medicine, Sendai, Japan. The Department of Pharmacology at Sendai has a long tradition of significant contribution to the development of drug therapy for cardiovascular diseases. The late Professor Koroku Hashimoto, the predecessor of Professor Norio Taira, first suggested the mode of action of calcium antagonists and their potential usefulness in therapy of ischemic heart disease and hypertension at an early stage of their development. The need for greater understanding of the pathophysiology of cardiovascular dis eases is more critical now than ever before because modern advances in basic and clinical sciences have prolonged the average life expectancy. Using a wide range of molecular and electrophysiological techniques, major advances are occurring frequently in the field of cardiovascular physiology and pharmacology. Such multifaceted approaches are preferred because human cardiovascular diseases are complex, requiring multiple interventions and an in-depth understanding of molecular mechanisms underlying the disease. The first section of this book focuses on molecular mechanisms of ion channel regulation. Eight of ten chapters in this section are devoted to the recent advances in molecular characterization and regulation of various types of potassium channels in cardiac, vascular, and neuronal tissues. A discussion of the structure and function of sodium and calcium channels is also included.

Immune - A Journey into the Mysterious System That Keeps You Alive (Hardcover): Philipp Dettmer Immune - A Journey into the Mysterious System That Keeps You Alive (Hardcover)
Philipp Dettmer
R1,038 Discovery Miles 10 380 Ships in 12 - 17 working days
Trace Elements, Micronutrients, and Free Radicals (Hardcover, 1991 ed.): Ivor E. Dreosti Trace Elements, Micronutrients, and Free Radicals (Hardcover, 1991 ed.)
Ivor E. Dreosti
R4,454 Discovery Miles 44 540 Ships in 10 - 15 working days

Itisonlyrecently thatthe naturaloccurrenceoffree radicalsin biological tissue has become widely accepted, and that the suspi- cion with which biologists previously viewed the free radicals of radiationchemistryhas beenplacedin a broaderperspective. Now, oxygen-derived free radicals are considered respectable biochemi- cal intermediates, given always the caveat that unwanted tissue damage may arise if these active species are produced in such abundance that they overwhelm the natural antioxidant and free- radical defense mechanisms, or if these systems have become hypoeffective. Many factors, including several dietary manipula- tions, can lead toelevatedproductionofsuperoxide and may result in free radical overload, whereas a deficiency of those micronutri- ents associated with the antioxidant defense mec.hanisms may re- sult in substantially diminished antioxidant capacity. By now, antioxidants have become a household word and al- most everyone is aware of their imponance in protecting the body against attack by active oxygen species. Indeed, it is a paradox of nature that oxygen, which is so essential to sustain aerobic life, ul- timately contributes to its destruction. Not surprisingly, recogni- tion ofthis dilemma has generated a spate ofantioxidant strategies intended to reduce the risk of tissue damage by rampant oxygen radicals, some sadly based less on science than on speculation.

Pregnancy and Parturition, Volume 1 (Hardcover): T. Zakar Pregnancy and Parturition, Volume 1 (Hardcover)
T. Zakar
R3,286 Discovery Miles 32 860 Ships in 12 - 17 working days

One of the mysteries of mammalian reproduction is the physiologic process that determines the length of gestation. The proper timing of birth ensures that the young individual is sufficiently developed to survive and adapt in the extrauterine environment, and that the mother is capable to provide nutrition and protection to the newborn. This volume summarizes new knowledge obtained by many researchers seeking to unravel the compile mechanisms that contribute to the maintenance and termination of pregnancy. The most important common goal of these efforts is to reduce the incidence of preterm birth, which is the leading cause of perinatal morbidity and mortality in numerous countries.
Separate chapters are devoted to the best-studied animal models of parturition. In sheep, the fetus is in control of the timing of its own birth, while in avian species, oviposition is evidently determined by the female laying the feritlized egg. In humans and non-human primates, the roles of the fetus and the mother are more balanced, and involve a complicated and poorly understood interplay between the mother, the fetus, and the placenta. Some major aspects of these interactions, such as trophoblast function, myometrial contractility, and the endocrine-paracrine systems, are discussed in further chapters.

Ethnography and Education Policy (Hardcover, 1st ed): Geoffrey Walford Ethnography and Education Policy (Hardcover, 1st ed)
Geoffrey Walford
R4,379 Discovery Miles 43 790 Ships in 12 - 17 working days

This book emphasises the central place that ethnographic work should have in the formulation and evaluation of education policy. Ethnographic studies contribute to a greater understanding of the process formulation, evaluation and critique. First, careful studies of policy initiatives at the local level can show the extent to which change actually occurs in practice. Second, ethnographic studies can investigate the unintended consequences as well as those planned by the policy. Third, ethnography can investigate the effects of policies in such a way that contradictions within the original policy itself are illuminated. As well as studying the effects and impact of policy, ethnography can also be useful in the formulation of new policies. The various chapters gathered together here give many examples of the ways that ethnography can trace the effects of particular policy developments and may be able to influence future policy debates. The contributors and case studies relate to several countries including the United States, Italy, England, France, Sweden and Switzerland, showing not only that ethnographic research in education is now widespread, but also increasing relevance to policy.

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