Biological and biomedical studies have entered a new era over the past two decades thanks to the wide use of mathematical models and computational approaches. A booming of computational biology, which sheerly was a theoretician's fantasy twenty years ago, has become a reality. Obsession with computational biology and theoretical approaches is evidenced in articles hailing the arrival of what are va- ously called quantitative biology, bioinformatics, theoretical biology, and systems biology. New technologies and data resources in genetics, such as the International HapMap project, enable large-scale studies, such as genome-wide association st- ies, which could potentially identify most common genetic variants as well as rare variants of the human DNA that may alter individual's susceptibility to disease and the response to medical treatment. Meanwhile the multi-electrode recording from behaving animals makes it feasible to control the animal mental activity, which could potentially lead to the development of useful brain-machine interfaces. - bracing the sheer volume of genetic, genomic, and other type of data, an essential approach is, ?rst of all, to avoid drowning the true signal in the data. It has been witnessed that theoretical approach to biology has emerged as a powerful and st- ulating research paradigm in biological studies, which in turn leads to a new - search paradigm in mathematics, physics, and computer science and moves forward with the interplays among experimental studies and outcomes, simulation studies, and theoretical investigations.

This book reviews nonparametric Bayesian methods and models that have proven useful in the context of data analysis. Rather than providing an encyclopedic review of probability models, the book's structure follows a data analysis perspective. As such, the chapters are organized by traditional data analysis problems. In selecting specific nonparametric models, simpler and more traditional models are favored over specialized ones. The discussed methods are illustrated with a wealth of examples, including applications ranging from stylized examples to case studies from recent literature. The book also includes an extensive discussion of computational methods and details on their implementation. R code for many examples is included in online software pages.

This book presents various recently developed and traditional statistical techniques, which are increasingly being applied in social science research. The social sciences cover diverse phenomena arising in society, the economy and the environment, some of which are too complex to allow concrete statements; some cannot be defined by direct observations or measurements; some are culture- (or region-) specific, while others are generic and common. Statistics, being a scientific method - as distinct from a 'science' related to any one type of phenomena - is used to make inductive inferences regarding various phenomena. The book addresses both qualitative and quantitative research (a combination of which is essential in social science research) and offers valuable supplementary reading at an advanced level for researchers.

This volume is composed of peer-reviewed papers that have developed from the First Conference of the International Society for NonParametric Statistics (ISNPS). This inaugural conference took place in Chalkidiki, Greece, June 15-19, 2012. It was organized with the co-sponsorship of the IMS, the ISI, and other organizations. M.G. Akritas, S.N. Lahiri, and D.N. Politis are the first executive committee members of ISNPS, and the editors of this volume. ISNPS has a distinguished Advisory Committee that includes Professors R.Beran, P.Bickel, R. Carroll, D. Cook, P. Hall, R. Johnson, B. Lindsay, E. Parzen, P. Robinson, M. Rosenblatt, G. Roussas, T. SubbaRao, and G. Wahba. The Charting Committee of ISNPS consists of more than 50 prominent researchers from all over the world. The chapters in this volume bring forth recent advances and trends in several areas of nonparametric statistics. In this way, the volume facilitates the exchange of research ideas, promotes collaboration among researchers from all over the world, and contributes to the further development of the field.The conference program included over 250 talks, including special invited talks, plenary talks, and contributed talks on all areas of nonparametric statistics. Out of these talks, some of the most pertinent ones have been refereed and developed into chapters that share both research and developments in the field.

This book focuses on the application and development of information geometric methods in the analysis, classification and retrieval of images and signals. It provides introductory chapters to help those new to information geometry and applies the theory to several applications. This area has developed rapidly over recent years, propelled by the major theoretical developments in information geometry, efficient data and image acquisition and the desire to process and interpret large databases of digital information. The book addresses both the transfer of methodology to practitioners involved in database analysis and in its efficient computational implementation.

This book presents selected peer-reviewed contributions from the International Work-Conference on Time Series, ITISE 2017, held in Granada, Spain, September 18-20, 2017. It discusses topics in time series analysis and forecasting, including advanced mathematical methodology, computational intelligence methods for time series, dimensionality reduction and similarity measures, econometric models, energy time series forecasting, forecasting in real problems, online learning in time series as well as high-dimensional and complex/big data time series. The series of ITISE conferences provides a forum for scientists, engineers, educators and students to discuss the latest ideas and implementations in the foundations, theory, models and applications in the field of time series analysis and forecasting. It focuses on interdisciplinary and multidisciplinary research encompassing computer science, mathematics, statistics and econometrics.

This book provides a general framework for learning sparse graphical models with conditional independence tests. It includes complete treatments for Gaussian, Poisson, multinomial, and mixed data; unified treatments for covariate adjustments, data integration, and network comparison; unified treatments for missing data and heterogeneous data; efficient methods for joint estimation of multiple graphical models; effective methods of high-dimensional variable selection; and effective methods of high-dimensional inference. The methods possess an embarrassingly parallel structure in performing conditional independence tests, and the computation can be significantly accelerated by running in parallel on a multi-core computer or a parallel architecture. This book is intended to serve researchers and scientists interested in high-dimensional statistics, and graduate students in broad data science disciplines. Key Features: A general framework for learning sparse graphical models with conditional independence tests Complete treatments for different types of data, Gaussian, Poisson, multinomial, and mixed data Unified treatments for data integration, network comparison, and covariate adjustment Unified treatments for missing data and heterogeneous data Efficient methods for joint estimation of multiple graphical models Effective methods of high-dimensional variable selection Effective methods of high-dimensional inference

The book covers a wide range of topics, yet essential, in Computational Finance (CF), understood as a mix of Finance, Computational Statistics, and Mathematics of Finance. In that regard it is unique in its kind, for it touches upon the basic principles of all three main components of CF, with hands-on examples for programming models in R. Thus, the first chapter gives an introduction to the Principles of Corporate Finance: the markets of stock and options, valuation and economic theory, framed within Computation and Information Theory (e.g. the famous Efficient Market Hypothesis is stated in terms of computational complexity, a new perspective). Chapters 2 and 3 give the necessary tools of Statistics for analyzing financial time series, it also goes in depth into the concepts of correlation, causality and clustering. Chapters 4 and 5 review the most important discrete and continuous models for financial time series. Each model is provided with an example program in R. Chapter 6 covers the essentials of Technical Analysis (TA) and Fundamental Analysis. This chapter is suitable for people outside academics and into the world of financial investments, as a primer in the methods of charting and analysis of value for stocks, as it is done in the financial industry. Moreover, a mathematical foundation to the seemly ad-hoc methods of TA is given, and this is new in a presentation of TA. Chapter 7 reviews the most important heuristics for optimization: simulated annealing, genetic programming, and ant colonies (swarm intelligence) which is material to feed the computer savvy readers. Chapter 8 gives the basic principles of portfolio management, through the mean-variance model, and optimization under different constraints which is a topic of current research in computation, due to its complexity. One important aspect of this chapter is that it teaches how to use the powerful tools for portfolio analysis from the RMetrics R-package. Chapter 9 is a natural continuation of chapter 8 into the new area of research of online portfolio selection. The basic model of the universal portfolio of Cover and approximate methods to computeare alsodescribed."

This volume presents the latest advances and trends in nonparametric statistics, and gathers selected and peer-reviewed contributions from the 3rd Conference of the International Society for Nonparametric Statistics (ISNPS), held in Avignon, France on June 11-16, 2016. It covers a broad range of nonparametric statistical methods, from density estimation, survey sampling, resampling methods, kernel methods and extreme values, to statistical learning and classification, both in the standard i.i.d. case and for dependent data, including big data. The International Society for Nonparametric Statistics is uniquely global, and its international conferences are intended to foster the exchange of ideas and the latest advances among researchers from around the world, in cooperation with established statistical societies such as the Institute of Mathematical Statistics, the Bernoulli Society and the International Statistical Institute. The 3rd ISNPS conference in Avignon attracted more than 400 researchers from around the globe, and contributed to the further development and dissemination of nonparametric statistics knowledge.

"We live in the age of data. In the last few years, the methodology of extracting insights from data or "data science" has emerged as a discipline in its own right. The R programming language has become one-stop solution for all types of data analysis. The growing popularity of R is due its statistical roots and a vast open source package library. The goal of "Beginning Data Science with R" is to introduce the readers to some of the useful data science techniques and their implementation with the R programming language. The book attempts to strike a balance between the how: specific processes and methodologies, and understanding the why: going over the intuition behind how a particular technique works, so that the reader can apply it to the problem at hand. This book will be useful for readers who are not familiar with statistics and the R programming language.

This book introduces the basic methodologies for successful data analytics. Matrix optimization and approximation are explained in detail and extensively applied to dimensionality reduction by principal component analysis and multidimensional scaling. Diffusion maps and spectral clustering are derived as powerful tools. The methodological overlap between data science and machine learning is emphasized by demonstrating how data science is used for classification as well as supervised and unsupervised learning.

This book presents the R software environment as a key tool for oceanographic computations and provides a rationale for using R over the more widely-used tools of the field such as MATLAB. Kelley provides a general introduction to R before introducing the 'oce' package. This package greatly simplifies oceanographic analysis by handling the details of discipline-specific file formats, calculations, and plots. Designed for real-world application and developed with open-source protocols, oce supports a broad range of practical work. Generic functions take care of general operations such as subsetting and plotting data, while specialized functions address more specific tasks such as tidal decomposition, hydrographic analysis, and ADCP coordinate transformation. In addition, the package makes it easy to document work, because its functions automatically update processing logs stored within its data objects. Kelley teaches key R functions using classic examples from the history of oceanography, specifically the work of Alfred Redfield, Gordon Riley, J. Tuzo Wilson, and Walter Munk. Acknowledging the pervasive popularity of MATLAB, the book provides advice to users who would like to switch to R. Including a suite of real-life applications and over 100 exercises and solutions, the treatment is ideal for oceanographers, technicians, and students who want to add R to their list of tools for oceanographic analysis.

Scientific Data Analysis using Jython Scripting and Java presents practical approaches for data analysis using Java scripting based on Jython, a Java implementation of the Python language. The chapters essentially cover all aspects of data analysis, from arrays and histograms to clustering analysis, curve fitting, metadata and neural networks. A comprehensive coverage of data visualisation tools implemented in Java is also included. Written by the primary developer of the jHepWork data-analysis framework, the book provides a reliable and complete reference source laying the foundation for data-analysis applications using Java scripting. More than 250 code snippets (of around 10-20 lines each) written in Jython and Java, plus several real-life examples help the reader develop a genuine feeling for data analysis techniques and their programming implementation. This is the first data-analysis and data-mining book which is completely based on the Jython language, and opens doors to scripting using a fully multi-platform and multi-threaded approach. Graduate students and researchers will benefit from the information presented in this book.

later versions. In addition, the CD-ROM contains a complete solutions manual that includes detailed solutions to all the problems in the book. If the reader does not wish to consult these solutions, then a brief list of answers is provided in printed form at the end of the book. Iwouldliketothankmyfamilymembersfortheirhelpandcontinuedsupportwi- out which this book would not have been possible. I would also like to acknowledge the help of the editior at Springer-Verlag (Dr. Thomas Ditzinger) for his assistance in bringing this book out in its present form. Finally, I would like to thank my brother, Nicola, for preparing most of the line drawings in both editions. In this edition, I am providing two email addresses for my readers to contact me (pkattan@tedata. net. jo and pkattan@lsu. edu). The old email address that appeared in the ?rst edition was cancelled in 2004. December 2006 Peter I. Kattan PrefacetotheFirstEdition 3 This is a book for people who love ?nite elements and MATLAB . We will use the popular computer package MATLAB as a matrix calculator for doing ?nite element analysis. Problems will be solved mainly using MATLAB to carry out the tedious and lengthy matrix calculations in addition to some manual manipulations especially when applying the boundary conditions. In particular the steps of the ?nite element method are emphasized in this book. The reader will not ?nd ready-made MATLAB programsforuseasblackboxes. Insteadstep-by-stepsolutionsof?niteelementpr- lems are examined in detail using MATLAB.

This book presents computer programming as a key method for solving mathematical problems. There are two versions of the book, one for MATLAB and one for Python. The book was inspired by the Springer book TCSE 6: A Primer on Scientific Programming with Python (by Langtangen), but the style is more accessible and concise, in keeping with the needs of engineering students. The book outlines the shortest possible path from no previous experience with programming to a set of skills that allows the students to write simple programs for solving common mathematical problems with numerical methods in engineering and science courses. The emphasis is on generic algorithms, clean design of programs, use of functions, and automatic tests for verification.

This book presents four mathematical essays which explore the foundations of mathematics and related topics ranging from philosophy and logic to modern computer mathematics. While connected to the historical evolution of these concepts, the essays place strong emphasis on developments still to come.

The book originated in a 2002 symposium celebrating the work of Bruno Buchberger, Professor of Computer Mathematics at Johannes Kepler University, Linz, Austria, on the occasion of his 60th birthday. Among many other accomplishments, Professor Buchberger in 1985 was the founding editor of the Journal of Symbolic Computation; the founder of the Research Institute for Symbolic Computation (RISC) and its chairman from 1987-2000; the founder in 1990 of the Softwarepark Hagenberg, Austria, and since then its director.

More than a decade in the making, Mathematics, Computer Science and Logic - A Never Ending Story includes essays by leading authorities, on such topics as mathematical foundations from the perspective of computer verification; a symbolic-computational philosophy and methodology for mathematics; the role of logic and algebra in software engineering; and new directions in the foundations of mathematics. These inspiring essays invite general, mathematically interested readers to share state-of-the-art ideas which advance the never ending story of mathematics, computer science and logic.

Mathematics, Computer Science and Logic - A Never Ending Story is edited by Professor Peter Paule, Bruno Buchberger s successor as director of the Research Institute for Symbolic Computation.

"

This volume features selected contributions on a variety of topics related to linear statistical inference. The peer-reviewed papers from the International Conference on Trends and Perspectives in Linear Statistical Inference (LinStat 2016) held in Istanbul, Turkey, 22-25 August 2016, cover topics in both theoretical and applied statistics, such as linear models, high-dimensional statistics, computational statistics, the design of experiments, and multivariate analysis. The book is intended for statisticians, Ph.D. students, and professionals who are interested in statistical inference.

This book provides a quick access to computational tools for algebraic geometry, the mathematical discipline which handles solution sets of polynomial equations. Originating from a number of intense one week schools taught by the authors, the text is designed so as to provide a step by step introduction which enables the reader to get started with his own computational experiments right away. The authors present the basic concepts and ideas in a compact way.

Mathematics is undoubtedly the key to state-of-the-art high technology. It is aninternationaltechnicallanguageandprovestobeaneternallyyoungscience to those who have learned its ways. Long an indispensable part of research thanks to modeling and simulation, mathematics is enjoying particular vit- ity now more than ever. Nevertheless, this stormy development is resulting in increasingly high requirements for students in technical disciplines, while general interest in mathematics continues to wane at the same time. This book and its appendices on the Internet seek to deal with this issue, helping students master the di?cult transition from the receptive to the productive phase of their education. The author has repeatedly held a three-semester introductory course - titled Higher Mathematics at the University of Stuttgart and used a series of "handouts" to show further aspects, make the course contents more motiv- ing, and connect with the mechanics lectures taking place at the same time. One part of the book has more or less evolved from this on its own. True to the original objective, this part treats a variety of separate topics of varying degrees of di?culty; nevertheless, all these topics are oriented to mechanics. Anotherpartofthisbookseekstoo?eraselectionofunderstandablereal- ticmodelsthatcanbeimplementeddirectlyfromthemultitudeofmathema- calresources.TheauthordoesnotattempttohidehispreferenceofNumerical Mathematics and thus places importance on careful theoretical preparation.

This beginner's introduction to MATLAB teaches a sufficient subset of the functionality and gives the reader practical experience on how to find more information. A forty-page appendix contains unique user-friendly summaries and tables of MATLAB functions enabling the reader to find appropriate functions, understand their syntax and get a good overview. The large number of exercises, tips, and solutions mean that the course can be followed with or without a computer. Recent development in MATLAB to advance programming is described using realistic examples in order to prepare students for larger programming projects.  Revolutionary step by step 'guided tour' eliminates the steep learning curve encountered in learning new programming languages. Each chapter corresponds to an actual engineering course, where examples in MATLAB illustrate the typical theory, providing a practical understanding of these courses. Complementary homepage contains exercises, a take-home examination, and an automatic marking that grades the solution. End of chapter exercises with selected solutions in an appendix. The development of MATLAB programming and the rapid increase in the use of MATLAB in engineering courses makes this a valuable self-study guide for both engineering students and practising engineers. Readers will find that this time-less material can be used throughout their education and into their career.

Given the explosion of interest in mathematical methods for solving problems in finance and trading, a great deal of research and development is taking place in universities, large brokerage firms, and in the supporting trading software industry. Mathematical advances have been made both analytically and numerically in finding practical solutions.

This book provides a comprehensive overview of existing and original material, about what mathematics when allied with Mathematica can do for finance. Sophisticated theories are presented systematically in a user-friendly style, and a powerful combination of mathematical rigor and Mathematica programming. Three kinds of solution methods are emphasized: symbolic, numerical, and Monte-- Carlo. Nowadays, only good personal computers are required to handle the symbolic and numerical methods that are developed in this book.

Key features: * No previous knowledge of Mathematica programming is required * The symbolic, numeric, data management and graphic capabilities of Mathematica are fully utilized * Monte--Carlo solutions of scalar and multivariable SDEs are developed and utilized heavily in discussing trading issues such as Black--Scholes hedging * Black--Scholes and Dupire PDEs are solved symbolically and numerically * Fast numerical solutions to free boundary problems with details of their Mathematica realizations are provided * Comprehensive study of optimal portfolio diversification, including an original theory of optimal portfolio hedging under non-Log-Normal asset price dynamics is presented

The book is designed for the academic community of instructors and students, and most importantly, will meet the everyday trading needs of quantitatively inclined professional and individual investors.

Over the past 80 years, the way that citation frequency was counted and analyzed changed dramatically from the early manual transcribing and statistical computation of citation data to computer-based citation data creation and its manipulation.""Author Cocitation Analysis: Quantitative Methods for Mapping the Intellectual Structure of an Academic Discipline"" provides a blueprint for researchers to follow in a wide variety of investigations. Pertinent to faculty, researchers, and graduate students in any academic field, this book introduces an alternative approach to conducting author cocitation analysis (ACA) without relying on commercial citation databases.

The Model-Free Prediction Principle expounded upon in this monograph is based on the simple notion of transforming a complex dataset to one that is easier to work with, e.g., i.i.d. or Gaussian. As such, it restores the emphasis on observable quantities, i.e., current and future data, as opposed to unobservable model parameters and estimates thereof, and yields optimal predictors in diverse settings such as regression and time series. Furthermore, the Model-Free Bootstrap takes us beyond point prediction in order to construct frequentist prediction intervals without resort to unrealistic assumptions such as normality. Prediction has been traditionally approached via a model-based paradigm, i.e., (a) fit a model to the data at hand, and (b) use the fitted model to extrapolate/predict future data. Due to both mathematical and computational constraints, 20th century statistical practice focused mostly on parametric models. Fortunately, with the advent of widely accessible powerful computing in the late 1970s, computer-intensive methods such as the bootstrap and cross-validation freed practitioners from the limitations of parametric models, and paved the way towards the `big data' era of the 21st century. Nonetheless, there is a further step one may take, i.e., going beyond even nonparametric models; this is where the Model-Free Prediction Principle is useful. Interestingly, being able to predict a response variable Y associated with a regressor variable X taking on any possible value seems to inadvertently also achieve the main goal of modeling, i.e., trying to describe how Y depends on X. Hence, as prediction can be treated as a by-product of model-fitting, key estimation problems can be addressed as a by-product of being able to perform prediction. In other words, a practitioner can use Model-Free Prediction ideas in order to additionally obtain point estimates and confidence intervals for relevant parameters leading to an alternative, transformation-based approach to statistical inference.

This book brings together two major trends: data science and blockchains. It is one of the first books to systematically cover the analytics aspects of blockchains, with the goal of linking traditional data mining research communities with novel data sources. Data science and big data technologies can be considered cornerstones of the data-driven digital transformation of organizations and society. The concept of blockchain is predicted to enable and spark transformation on par with that associated with the invention of the Internet. Cryptocurrencies are the first successful use case of highly distributed blockchains, like the world wide web was to the Internet. The book takes the reader through basic data exploration topics, proceeding systematically, method by method, through supervised and unsupervised learning approaches and information visualization techniques, all the way to understanding the blockchain data from the network science perspective. Chapters introduce the cryptocurrency blockchain data model and methods to explore it using structured query language, association rules, clustering, classification, visualization, and network science. Each chapter introduces basic concepts, presents examples with real cryptocurrency blockchain data and offers exercises and questions for further discussion. Such an approach intends to serve as a good starting point for undergraduate and graduate students to learn data science topics using cryptocurrency blockchain examples. It is also aimed at researchers and analysts who already possess good analytical and data skills, but who do not yet have the specific knowledge to tackle analytic questions about blockchain transactions. The readers improve their knowledge about the essential data science techniques in order to turn mere transactional information into social, economic, and business insights.

The first edition (94301-3) was published in 1995 in TIMS and had 2264 regular US sales, 928 IC, and 679 bulk.

This new edition updates the text to Mathematica 5.0 and offers a more extensive treatment of linear algebra. It has been thoroughly revised and corrected throughout.