This book has built on the work that was presented in the previous Fascicles of the Third and Fourth Series. The authors' vast experience has led to new understanding of many aspects of pituitary pathology. With modern immunostaining and molecular techniques, classification of pituitary disease is becoming easier. Furthermore, the availability of targeted therapies has augmented the role of the pathologist in determining an accurate diagnosis. This updated volume addresses modern techniques and their application to treatment of pituitary neoplasms but retains the detailed foundation of morphology in a lushly illustrated tome, the cornerstone of the AFIP fascicles.

As the recent war in Lebanon demonstrated, an understanding of the Lebanese Shi'ite militant group Hizbullah remains an important component of any attempt to solve the problems of the Middle East. "The Shifts in Hizbullah's Ideology" provides an in-depth analysis of the group's motivations, tracking the changes it has undergone since Hizbullah's founding by Lebanese Shi'ite clergy in 1978. Joseph Alagha demonstrates that Hizbullah, driven at its founding chiefly by religious concerns, in the latter half of the 1980s became a full-fledged social movement, with a structure and ideology aimed at social change. Further changes in the 1990s led to Hizbullah's becoming a mainstream political party--but without surrendering its militarism or willingness to use violence to advance its ends.
In tracking these changes, "The Shifts in Hizbullah's Ideology" covers such disparate topics as Hizbullah's views of jihad, suicide and martyrdom, integration, pan-Islamism, anti-Zionism, and the relationship with Israel and the United States. It will be necessary reading for both scholars and policymakers.

Psychiatry is arguably the most misunderstood specialty in modern medicine and psychiatrists are often thought of as part physician, part confessor, part police officer, and part shaman. In Demystifying Psychiatry, two eminent psychiatrists offer an illuminating look at the entire field, offering a clear and informative portrait of a medical specialty often clouded in myth. Zorumski and Rubin range from a basic discussion of what psychiatry is, to the types of illnesses psychiatrists treat, the training of psychiatrists, the treatment of psychiatric disorders (covering medications, psychotherapy, lifestyle interventions, electroconvulsive therapy, and much more), and how families can help with treatment. They caution the consumer about practices that should raise red flags. The book also covers new trends in psychiatry and explores the future of the field, predicting that major advances in genetics and neuroscience will lead to rapid and amazing changes in psychiatry. The book concludes with extensive reference materials that will be valuable both to general readers and medical practitioners.

Health Promotion in Midwifery explores the principles of health promotion within the practical context of midwifery. It clearly outlines and discusses the midwife's role in health promotion, making it essential reading for all student and practising midwives, as well as clinical practitioners. Emphasizing the link between theory and practice, the second edition incorporates chapters on domestic violence, sexual health, breastfeeding, and mental health promotion. Text boxes make the text accessible and user-friendly and case studies and summaries put the material in practical context. Additional readings encourage readers to further research and reflection on their own practice. Throughout the book, the importance of the role of the midwife in health promotion is emphasized. This second edition brings together contributions from a variety of experienced practitioners.

This volume is a comprehensive source of information on the fundamentals of hearing and sound physics. Using research from 1980 onward, this book is a critical review of past and up-to-date research findings and concepts on the effects of noise on people; it focuses on the psychological and physiological affects of noise on hearing and performance. This text elucidates the interrelations of the acoustical, physiological, psychological, and sociological factors that are involved in making noise a problem to individuals and societies. Also discussed are hearing loss, speech communications, annoyance, and health effects criteria for the limitation of exposures to noise in living and work areas. It covers: physical characteristics of sound and noise; acoustical-sensorineural response characteristics of the ear; basic psychological sensations and perceptions that ensue from analysis of sound and noise by the auditory system; laboratory and real-life research on the impairments to hearing, speech communication, task performance, and mental and bodily health that occur from exposure to noise; and, physical measures which predict adverse effects on hearing, behavior, and health from exposure to noise.

This book tells the extraordinary story of how the function of the first - and so far almost the only - human organ was replaced by a machine, and the "artificial kidney" entered medical and public folk-lore. A practical artificial kidney, or dialyser, came about by advances in science followed by the acquisition of new synthetic materials which made the application of these ideas possible. However it was the dedication and persistence of a number of talented pioneers who pressed ahead against professional opposition to achieve success, first in the treatment of temporary, recoverable kidney failure, and then permanent renal shut-down which made it a success. The apparent high cost and limited availability of this form of treatment immediately raised ethical questions which had never been questioned before, centering around equity of access to treatment, when and if treatment could be denied, and - worst of all - the agonising decision of when, once established, it should be stopped. Spiralling costs as the true number of people with kidney failure became evident raised major political and financial questions, which were addressed in different countries in different ways which reflected - but also helped change - patterns of how medical care is provided. In developed countries, the problem could be solved by allocating a disproportionate amount of money to the treatment of relatively few kidney patients, but in the developing world the cost of treatment still limits its availability, as it does all forms of modern health care. Nevertheless, today almost one million people world-wide are maintained alive following terminal kidney failure, two thirds of them by various forms of dialysis and the remainder bearing kidney transplants, almost always placed after a period on dialysis. The story is also the sum of the often heroic lives of these hundreds of thousands of patients, a few of whom have today been maintained alive and active for more than 35 years, and many of whom suffered known, but also unexpected complications as a result of their treatment.

From smartphones to social media, from streaming videos to fitness bands, our devices bring us information and entertainment all day long, forming an intimate part of our lives. Their ubiquity represents a major shift in human experience, and although we often hold our devices dear, we do not always fully appreciate how their nearly constant presence can influence our lives for better and for worse. In this second edition of How Fantasy Becomes Reality, social psychologist Karen E. Dill-Shackleford explains what the latest science tells us about how our devices influence our thoughts, feelings, and behaviors. In engaging, conversational prose, she discusses both the benefits and the risks that come with our current level of media saturation. The wide-ranging conversation explores Avatar, Mad Men, Grand Theft Auto, and Comic Con to address critical issues such as media violence, portrayals of social groups, political coverage, and fandom. Her conclusions will empower readers to make our favorite sources of entertainment and information work for us and not against us.

Presented in a concise and readable format, Pediatric Radiology provides a comprehensive review of 120 pathologies commonly encountered by practicing radiologists and residents. As part of the Rotations in Radiology series, this volume offers a guided approach to imaging diagnosis with a constant depth of coverage, a structured template, and incorporation of applied physics, distinguishing it from other texts in the field. A definition is given for each pathology in this volume, followed by: demographics, clinical presentation, imaging modalities and features, imaging algorithm, applied physics, differential diagnoses and pitfalls, and a bulleted summary of key points. Designed for point-of-care use while training on a specific rotation, as well as for exam review and ongoing reference, Pediatric Radiology is the perfect tool to impart to residents, as well as to refresh for practitioners, the essential facts of common pathologies and the various modalities used to interpret them.

The context for this interdisciplinary work by a philosopher and a clinician is the psychiatric care provided to those with severe mental disorders. Such a setting makes distinctive moral demands on the very character of the practitioner, it is shown, calling for special virtues and greater virtue than many other practice settings. In a practice so attentive to the patient's self identity, the authors promote a heightened awareness of cultural and particularly gender issues. By elucidating the nature of the moral psychology and character of the good psychiatrist, this work provides a sustained application of virtue theory to clinical practice. With its roots in Aristotelian writing, The Virtuous Psychiatrist presents virtue traits as habits, able to be cultivated and enhanced through training. The book describes these traits, and how they can be habituated in clinical training. A turn towards virtue theory within philosophy during the last several decades has resulted in important research on professional ethics. By approaching the ethics of psychiatric professionals in these virtue terms, Radden and Sadler's work provides an original application of this theorizing to practice. Of interest to both theorists and practitioners, the book explores the tension between the model of enduring character implicit in virtue theory and the segmented personae of role-specific moral responses. Clinical examples are provided, based upon dramaturgical vignettes (caseplays) which illustrate both the interactions of the case participants as well as the inner monologue of the clinician protagonist.

Neeltje Elisabeth Langeveld (1954) worked at the Emma Children's Hospital where she was promoted to the position of Research Nurse in the Children's Cancer Department. From 1990 she trained in Clinical Epidemiology for Nurses at the AMC. In 1996 she started the research which is the subject of this dissertation. She will remain active as Research Nurse in the Children's Cancer Department when she has completed it. This dissertation focuses on aspects of the quality of life of young adults who have recovered from childhood cancer. Some fivehundred childhood cancer survivors, aged from 16 to 49 years, were asked to complete a questionnaire during their annual clinical check up at the 'Polikliniek Late Effecten Kindertumoren' (plek). The dissertation compares the results with a control group of subjects who had never suffered from cancer.

How does AI compare to a doctor when it comes to saving lives?

Doctors are under-resourced and face unprecedented levels of stress, with rising patient numbers and ever developing medical knowledge. But at the same time, they are all too human, prone to racial, class and social biases that affect the care patients receive.

Can we improve patient experience and alleviate the burdens of doctors at the same time? In this groundbreaking study, Charlotte Blease reveals how AI, if handled with care, could emerge as the most reliable physician in history.

Drawing on interviews with authorities in AI, doctors and patients, Blease shows how technology – despite some resistance – is already making a difference. From diagnosis and second opinions to treatment and aftercare, AI has the potential to revolutionize our healthcare.

Start preparing for your future…today! Develop the test-taking skills you need to prepare for your certification examination and build the knowledge base you need to successfully enter practice. Begin with high-yield content reviews of must-know disorders; then quiz yourself with questions reflecting those found on the ANCC and AANP certification examinations. More than 2,500 questions with detailed rationales for both correct and incorrect responses to help you hone your diagnostic and treatment reasoning skills. Looking for more NP certification resources? Boost your chances for success with Family Practice and Adult-Gerontology Primary Care Nurse Practitioner Certification Examination. Purchase both books together for a discounted price here.  A must have for FNP study!! "My most valuable asset for FNP study! I used this throughout my FNP program and highly recommend it! Fitzgerald uses easy to learn concepts and helps you to remember key concepts necessary to practice! Passed my AANP on my first attempt!" - Brandee, Online Reviewer "This book is amazing. Not only did it help me pass my... certification on the first try, but has also become my trustworthy resource in practice." - Rob, Online Reviewer Great material not just to review for certification boards. "Great material not just to review for certification boards, but also FNP students looking for short summaries of key information." - James D., Online Reviewer

The second edition of this award-winning textbook has been thoroughly revised and updated throughout. Building on the success of the first edition, the book continues to address the History and Practice of Forensic Psychiatry, Legal Regulation of the Practice of Psychiatry, Psychiatry in relation to Civil Law, Criminal Law, and Family Law. Important sections such as Special Issues in Forensic Psychiatry, Law and the Legal System, and Landmark Cases in Mental Health Law are included. Designed to meet the needs of practitioners of forensic psychiatry, for residents in forensic psychiatry, and those preparing for the specialty examination in Forensic Psychiatry of the American Board of Psychiatry and Neurology, this volume will also answer the many questions faced by mental health professionals, mental health administrators, correctional health professionals and correctional health administrators, attorneys, judges, probation and parole officers and administrators all of whom, at one time or another, require a substantive presentation of the entire field of forensic psychiatry in the USA.

The role of parasites and pathogens in the evolution of life history traits is of increasing interest to both ecologists and evolutionary biologists. Immunology, which was once studied almost exclusively by immunologists, has become an important area of proximate investigation to animal physiologists as a means for understanding changes in disease susceptibility and the neural and neuroendocrine mechanisms that mediate these changes. The coalescence of these different perspectives has given rise to the field of ecological immunology, an interdisciplinary research field that examines interactions among host physiology and disease ecology in a wide range of environmentally relevant contexts. The goal of ecological immunology is to understand immune function in the context of life-history traits across a wide range of organisms. Research within the field combines diverse approaches from a wide range of scientific disciplines including evolution, ecology, and life history theory to endocrinology, neuroscience, molecular biology, and behavior. This book critically reviews recent advances in the discipline of ecoimmunology. Chapters are written by experts in their respective fields and cover diverse topics including how environmental factors can affect host immune function, the complex dynamics among host immunity, pathogen prevalence and disease susceptibility, and the physiological mechanisms that lead to adaptive changes in immune responses. By integrating analyses of immune system function within animal biology, investigators will gain will gain a more comprehensive and satisfying understanding of organism-environment interactions at both ultimate and proximate levels of analysis.

Dendrites are complex neuronal structures that receive and integrate synaptic input from other nerve cells. They therefore play a critical role in brain function. Although dendrites were discovered over a century ago, due to the development of powerful new techniques there has been a dramatic resurgence of interest in the properties and function of these beautiful structures. This is the third edition of the first book devoted exclusively to dendrites. It contains a comprehensive survey of the current state of dendritic research across a wide range of topics, from dendritic morphology, evolution, development, and plasticity through to the electrical, biochemical and computational properties of dendrites, and finally to the key role of dendrites in brain disease. The third edition has been thoroughly revised, with the addition of a number of new chapters and comprehensive updates or rewrites of existing chapters by leading experts. "Dendrites" will be of interest to researchers and students in neuroscience and related fields, as well as to anyone interested in how the brain works.

The science of autism has seen tremendous breakthroughs in the past few decades. A multitude of relatively rare mutations have been identified to explain around 15 % of autism cases with many of these genetic causes systematically examined in animal models. This marriage of human genetics and basic neurobiology has led to major advances in our understanding of how these genetic mutations alter brain function and help to better understand the human disease. These scientific approaches are leading to the identification of potential therapeutic targets for autism that can be tested in the very same genetic models and hopefully translated into novel, rational therapies. The Autisms: Molecules to Model Systems provides a roadmap to many of these genetic causes of autism and clarifies what is known at the molecular, cellular, and circuit levels. Focusing on tractable genetic findings in human autism and painstakingly dissecting the underlying neurobiology, the book explains, is the key to understanding the pathophysiology of autism and ultimately to identifying novel treatments.

A refreshing, accessible roadmap to adapting to life as an ADHDer, designed with self-acceptance and advocacy in mind." - Devon Price, PhD - Social Psychologist and author of Unmasking Autism

A compassionate guide for everyone grappling with their neurodiversity

Accepting a label or receiving a formal diagnosis is only the tip of the iceberg when it comes to neurodivergence. Your ADHD doesn't exist in a vacuum: your upbringing, your culture, your relationships and any other conditions you might have, such as autism, depression or anxiety, all affect your experience as a neurodivergent individual. Navigating these intersecting areas can be challenging - but it isn't impossible.

Tip of the ADHD Iceberg offers a sensitive exploration of the nuances of neurodiversity, preparing you for the whirlwind that can come after a late diagnosis and equipping you with the essential tools for self-advocacy. In this book, ADHD Girls Founder and award-winning keynote speaker Dr Sam Hiew expertly blends her lived experience of ADHD and autism with her background in medical science to create a deeply empathetic guide to processing your diagnosis in the context of your whole life, from your personal relationships to the workplace environment.

Affirming, vindicating and empowering, you will learn to heal from a life of flying under the radar as well as how to prepare yourself for the road ahead.

Using the authors' over thirteen years of experience at the psychosis-risk clinic at Yale University School of Medicine, The Psychosis-Risk Syndrome presents a concise handbook that details the diagnostic tools and building blocks that comprise the Structural Interview for Psychosis-Risk Syndromes, or SIPS. Clear and to the point, this volume provides an in-depth description of this new clinical high-risk population, along with instructions on how to use the SIPS to evaluate persons for psychosis-risk.
The handbook's main section takes the reader step-by-step through the SIPS evaluation, tracking how patients and families find their way to the clinic, the initial interview, the evaluation process, and the summary session consisting of findings and future options. The core diagnostic symptoms of the SIPS and psychosis-risk states are illustrated with dozens of symptom and case examples drawn from real but disguised patients from the Yale clinic. With an emphasis on clinical usefulness, the handbook finishes with "practice cases" for the reader to test his or her new skills at evaluating clinical populations for psychosis-risk.

In 2003 the role of government in the regulation of cannabis is as hotly debated as it was a century ago. In this lively study James Mills explores the historical background of cannabis legislation, arguing that the drive towards prohibition grew out of the politics of empire rather than scientific or rational assessment of the drug's use and effects.

The onset of the quadruple burden of disease in South Africa, the challenges faced by the medical establishment to curtail the rapid growth of multiple epidemics, the inadequate response by the state to various inequities in the health system, and the public debates associated with it, have all combined to draw attention to the sociological aspects of health and disease. Sociology as a resource of knowledge and a unique analytical and conceptual perspective can be used to understand, explain and positively influence the course of health and disease in South African society and our responses to it. As a health practitioner or scholar you must be equipped with the skills to critically evaluate research and debates in your profession, be able to adapt to changes and contribute to the development of knowledge and best practice. This reader will familiarise you with relevant content and assist you to develop the analytical capacity and conceptual skills you will need. Society, Health and Disease in South Africa is authored by experienced educators and researchers in the fi elds of sociology, social work, anthropology, healthcare policy and practice.

This is a practical guide to the management of mild head injury, or concussion. It is now generally accepted that post-concussion syndrome has an organic basis and this has resulted in the emergence of clinics, staffed by interdisciplinary teams, dedicated to addressing the problem. After a short account of the history of thinking on mild head injury and its epidemiology, a section on pathology provides the background to the clinical picture. The coverage then moves on to look at the acute stage and management in the emergency department, followed by a description of the clinical features of the persisting symptoms. There are clear descriptions of the measurements, investigations and examinations to be completed. The authors then move on to look at the neurological, cognitive-behavioural and psychiatric aspects of management and treatment. Specific cases are discussed, including the special considerations when dealing with children, the elderly, executives and sportspeople. At the end of the book there are copies of information sheets and booklets for patients. Philip Wrightson and Dorothy Gronwall are pioneers in this field. They were the first to define test procedures to measure the changes following concussion, and to establish a clinic for those with persisting problems.

Keeping doctors happy and productive requires a thorough understanding of the systemic causes and consequences of physician stress, as well as the role of resilience in maintaining a healthy mental state. The pressure of making life-or-death decisions along with those associated with the day-to-day challenges of doctoring can lead to poor patient care and communication, patient dissatisfaction, absenteeism, reductions in productivity, job dissatisfaction, and lowered retention. This edited volume will provide a comprehensive tool for understanding and promoting physician stress resilience. Specifically, the book has six interrelated objectives that, collectively, would advance the evidence-based understanding of (1) the extent to which physicians experience and suffer from work-related stress; (2) the various manifestations, syndromes, and reaction patterns directly caused by work-related stress; (3) the degree to which physicians are resilient in that they are successful or not successful in coping with these stressors; (4) the theories and direct evidence that account for the resilience; (5) the programs during and following medical school which help to promote resilience; and (6) the agenda for future theory, research, and intervention efforts for the next generation of physicians.

Psychiatric Pharmacogenomics is a book written to help clinicians to use pharmacogenomic testing to improve the pharmacotherapy that they provide for their patients. It is designed to teach clinicians how to order pharmacogenomic tests and interpret the results. Clinical examples are used to underscore the specific indications for pharmacogenomic testing and to clarify the clinical usefulness of identifying atypical genotypes that result in problematic responses to medication.
The first section of the book begins with a basic review of molecular genetics. Additionally, the book also includes an extensive glossary of technical terms associated with molecular genetics and pharmacogenomics. The clinical utility of pharmacogenomic testing is demonstrated throughout the book by describing the implications of genetic variations for the care of individual patients.
The second section of the book is organized into fourteen chapters that each focus on the clinical implications of testing for specific genes for which variants have been associated with either therapeutic response or side effects of psychotropic medications. Each of these chapters is structured in the same manner and involves a description of the gene and its significant variants. Each chapter also includes one or more clinical vignettes.
The third section of the book discusses the clinical usefulness of pharmacogenomic testing, ethical issues associated with pharmacogenomic testing, and provides predictions for the future development of more sophisticated pharmacogenomic testing.