Unit 1: General Pathology Unit 2: Systemic Pathology Unit 3: Clinical PathologyÂ--Hematology Unit 4: Clinical PathologyÂ--Others Unit 5: Genetics Index

The Encyclopedia of Heart Diseases is an accurate and reliable source of in-depth information on the diseases that kill more than 12 million individuals worldwide each year. In fact, cardiovascular diseases are more prevalent than the combined incidence of all forms of cancer, diabetes, asthma and leukemia. In one volume, this Encylopedia thoroughly covers these ailments and also includes in-depth analysis of less common and rare heart conditions to round out the volume's scope. Researchers, clinicians, and students alike will all find this resource an invaluable tool for quick reference before approaching the primary literature.
* Coverage of more than 200 topics, including: applied pharmacology of current and experimental cardiac drugs, gene therapy, MRI, electron-beam CT, PET scan put in perspective, cardiac tests costs and justification, and new frontiers in cardiovascular research
* More than 150 helpful figures and illustrations
* Dr. Khan is a well-published and respected expert in heart and heart diseases

Anxiety is ubiquitous in everyday life and avoiding sources of anxiety is often at the core of our everyday choices and can even shape our life plans. But why are we all so anxious, when is this normal uniqueness as opposed to a diagnosable anxiety disorder, and why have anxiety disorders become more prevalent than ever? In All We Have to Fear, Horwitz and Wakefield argue that psychiatry has largely generated this epidemic by inflating our socially inconvenient, yet natural, fears into psychiatric disorders and ignoring our biologically designed natures, thus allowing the overdiagnosis of anxiety disorders and facilitating a culture of medicalization. The result is a society that is afraid of natural, biologically designed feelings of fear and, overall, anxious about feeling anxious. All We Have to Fear is a groundbreaking and fresh look at how to distinguish between anxiety conditions that are mental disorders, those that are natural reactions to threats, and those that are natural products of evolution. Building on the new science of evolutionary psychology, Horwitz and Wakefield demonstrate a mismatch between our basic biological natures and the environment that we have created for ourselves. Some of our natural anxiety is born from situations and objects that posed serious risks during prehistory, but that are no longer usually dangerous, for example, a city dweller who is terrified of snakes. This mismatch generates normal anxiety when there is, in fact, no real danger. Evolutionary psychology shows that beyond the context in which the symptoms occur, our biological heritage as a species must be considered in any psychiatric diagnosis as we are otherwise bewildered by our own primitive fears and beset by diffuse anxieties that seem to have no function in our lives. All We Have to Fear argues that only by paying attention to our evolutionary shaping can we understand ourselves, our fears, what is normal versus disordered in what we fear, and make informed choices about how to approach these fears. The mismatch between our natures, environment, and our fears is not pathological, but rather reveals the forces that shaped us and provides an "emotional time machine," shedding light on who we were when we were shaped as a species, and thus, allowing us more insight into who we are today.

Comprehensive Disability Management articulates current disability management knowledge and provides insight into new concepts. Practitioners of disability management come from many diverse health and health related professions such as nursing, psychology, occupational therapy, etc. Disability management is an emerging profession without adequate reference materials. As professionals, disability management practitioners have a significant impact on the financial and human costs of disability. Most major corporations have the need for a disability management program and therefore require individuals with skills to perform these functions. The financial costs of disability in corporations are one of the key target areas that require attention. The human costs of disability are also dramatic and efforts need to be made to reduce the impact of disabilities on individuals. The book documents proven techniques in disability management for practitioners in the field. It introduces the first theoretical model in this developing profession and provides practical examples on how to implement and manage an effective disability management program. The approach commences with an overview and the history of disability management as a developing practice area. The authors establish a theoretical base for disability management to guide the activities of practitioners in the field. They then translate the theory into action paradigms and address important issues around the disability management process including role definitions and discussions on key components. The disability management process, including claim initiation, claims management, return to work and rehabilitation, will be discussed. The important aspects of data analysis and quality assurance in program evaluation for this field are also considered. The book addresses the core aspects of disability management knowledge, skills and capabilities and reviews in detail the factors that influence the ability to effectively perform disability management in today's workplaces. It also looks at the interaction of the workplace organization. Formulates the business case for disability management in an organization, helping the reader understand how disability management fits into the overall functioning of a corporation. Presents a theoretical model that recognizes the influence of multiple issues on a disability outcome. Reviews proven disability management techniques for ensuring evidence-based best practice treatments.

Maintaining quality of life in an ageing population is one of the great challenges of the 21st Century. This book and collection of illustrated CD lectures summarises how this challenge is being met by multi-disciplinary developments of specialty biomaterials, devices, artificial organs and in-vitro growth of human cells as tissue engineered constructs.
Biomaterials, Artificial Organs and Tissue Engineering is intended for use as a textbook in a one semester course for upper level BS, MS and Meng students. The 25 chapters are organized in five parts: Part one provides an introduction to living and man-made materials for the non-specialist; Part two is an overview of clinical applications of various biomaterials and devices; Part three summarises the bioengineering principles, materials and designs used in artificial organs; Part four presents the concepts, cell techniques, scaffold materials and applications of tissue engineering; Part five provides an overview of the complex socio-economic factors involved in technology based healthcare, including regulatory controls, technology transfer processes and ethical issues. Each chapter is supplemented with illustrated Power Point lectures and study questions in an easy to use CD to aid the reader in self-paced instruction.
Comprehensive introduction to living and man-made materialsLooks at clinical applications of various biomaterials and devicesBioengineering principles, materials and designs used in artificial organs are summarised

The word concussion used to be unheard of in youth sports a decade ago. The brain injury was indeed occurring, but coaches and parents were encouraging their youth athletes to "shake it off" after "getting their bell rung". Science and increased awareness about concussion are transforming the way youth parents, coaches, and players pursue athletics. Fear of incurring concussions, as well as incorrect information, is leading some parents to keep their children out of contact sports, such as football and soccer, where concussion is more prevalent. Back in the Game: Why Concussion Doesn't Have to End Your Athletic Career does not dwell on perpetuating fears, but rather, provides the most up-to-date understanding of the condition. This text includes a real-world discussion of what science and medicine knows, what parents and coaches need to understand about concussions, evaluation and treatment, and possible post-concussive issues, like depression. At the heart of this book, the authors delve into these issues, explaining them in a clear and understandable way. The expertise and experiences of noted sports neurologist Jeffrey Kutcher, MD, along with reporting and interviews by award-winning sports journalist Joanne C. Gerstner, makes this book a timely, relevant, and real discussion about concussions in youth sports. Athletes and professional coaches who have participated in the formation of this book include two-time Olympic gold medalist soccer player Kate Markgraf, former NHL/Team Canada head coach Andy Murray, champion X-Games snowboarder Ellery Hollingsworth, along with an array of youth parents, coaches, and athletes from across the country.

The field of non-viral vector research has rapidly progressed since the publication of the first edition. This new edition is expanded to two separate volumes that contain in-depth discussions of different non-viral approaches, including cationic liposomes and polymers, naked DNA and various physical methods of delivery, as well as a comprehensive coverage of the molecular biological designs of the plasmid DNA for reduced toxicity, prolonged expression and tissue or disease specific genes. New developments such as the toxicity of the non-viral vectors and recent advances in nucleic acid therapeutics are fully covered in these volumes.

An invaluable desk reference for busy public health practitioners,
The Dictionary of Public Health is an alphabetical listing of almost 5,000 words and phrases used in public health science and practice. It offers definitions, discussion, and an occasional brief commentary on the relevance of each term to people and their health. This volume is a trusted resource for answers to questions that arise in the course of public health practice, whether in the office or in the field, in interactions with the public or with the media.
The book contains cross-referenced definitions and discussions of related terms and concepts. For easy reference, users will find similarly worked definitions and discussions of important related concepts listed under each of the commonly used keywords. A variety of website links make it easy to find further information at the users fingertips. Covering all aspects of public health, this book serves as both a quick and handy reference tool and a vehicle for more leisurely browsing.

This third volume of NMR Spectroscopy in the Undergraduate Curriculum continues the work we started with the first and second volumes in providing effective approaches for using nuclear magnetic resonance spectrometers as powerful tools for investigating a wide variety of phenomena at the undergraduate level. This volume focuses on upper-level courses and NMR spectroscopy across the curriculum. The applications and strategies in this volume will be helpful to those who are looking to transform their curriculum by integrating more NMR spectroscopy, to those who might not have considered NMR spectroscopy as a tool for solving certain types of problems, or for those seeking funding for a new or replacement NMR spectrometer.

High pressure liquid chromatography-frequently called high performance liquid chromatography (HPLC or, LC) is the premier analytical technique in pharmaceutical analysis and is predominantly used in the pharmaceutical industry. Written by selected experts in their respective fields, the Handbook of Pharmaceutical Analysis by HPLC Volume 6, provides a complete yet concise reference guide for utilizing the versatility of HPLC in drug development and quality control. Highlighting novel approaches in HPLC and the latest developments in hyphenated techniques, the book captures the essence of major pharmaceutical applications (assays, stability testing, impurity testing, dissolution testing, cleaning validation, high-throughput screening).

The latest title in the Real World Nursing Survival Guide series, this fun and engaging book makes it easy to review must-know concepts associated with hemodynamic monitoring. Its lighthearted, cartoon-filled approach guides readers through challenging concepts and procedures. The book begins with an overview of five main concepts: cardiac output, stroke volume, preload, afterload, and contractility. It discusses equipment used for specific procedures, followed by discussions of specific aspects of hemodynamic monitoring including cardiac output, intra-arterial, central venous, pulmonary artery, and mixed venous oxygenation. The final chapter focuses on clinical applications with case studies, clinical interventions, and exercises. The unique presentation of content narrows the gap between the knowledge a student learns during nursing school and the wisdom they need to survive in the real world. Material is presented using adult learning principles and various active-learning strategies to engage readers of all ages, backgrounds, and learning styles. A consistent chapter format - using the headings What it is, What you need to know, What you do, and Do you understand? - breaks down information into small segments and facilitates understanding. Special icons for Lifespan Considerations, Cultural Implications, Web Links, Cautions, Monitoring and Initial Treatment help readers quickly identify special content in the chapter. A variety of memory-reinforcing activities such as mnemonic devices, fill-in the blank, matching, word jumbles, true/false, and crossword puzzles promote learning and understanding. Clinical terms and shorthand expressions are highlighted in colored text within parentheses after the explanation, to expose readers to terminology used in the practice setting. Boxed Take Home Points distill years of nursing experience into practical, "real world" advice from the experts. More than 100 NCLEX-style questions, divided by chapter, are included in a section at the end of the book so readers can test their knowledge and review challenging concepts. Full-color illustrations demonstrate key concepts and principles of hemodynamic monitoring, including various complications. Original cartoon-character illustrations and a cartoon camel walk readers through subjects that nursing students have identified as difficult, using a lighthearted approach. Waveforms at the end of each chapter allow readers to practice their interpretation.

This indispensable guide gives concise yet comprehensive descriptions of the pulse sequences commonly used on modern MRI scanners. The book consists of a total of 65 self-contained sections, each focused on a single subject. Written primarily for scientists, engineers, radiologists, and graduate students who are interested in an in-depth understanding of various MRI pulse sequences, it serves readers with a diverse set of backgrounds by providing both non-mathematical and mathematical descriptions.
The book is divided into five parts. Part I of the book describes two mathematical tools, Fourier transforms and the rotating reference frame, that are useful for understanding MRI pulse sequences. The second part is devoted to a wide variety of radiofrequency (RF) pulses, and the third part focuses on gradient waveforms. Data acquisition, image reconstruction, and physiological monitoring related to pulse sequence design form the subject of Part IV of the book. Once this foundation is established, Part V of the book describes the underlying principles, implementation, and selected applications of many pulse sequences commonly in use today.
The extensive topic coverage and cross-referencing makes this book ideal for beginners learning the building blocks of MRI pulse sequence design, as well as for experienced professionals who are seeking deeper knowledge of a particular technique.
-Explains pulse sequences, their components, and the associated image reconstruction methods commonly used in MRI
-Provides self-contained sections for individual techniques
-Can be used as a quick reference guide or as a resource for deeper study
-Includes both non-mathematical andmathematical descriptions
-Contains numerous figures, tables, references, and worked example problems

This brand-new book offers virtual hands-on experience to over 65 emergency procedures, allowing readers to rehearse them over again in their mind-then perform them on demand correctly. Colour drawings of each procedure that illuminate relevant anatomical structures and their relationship to each new step paired with full-colour photographs provide a realistic clinical view of the identical anatomy. Plus, each step is accompanied by concise text, allowing the illustrations and photographs to guide clinicians effortlessly through the procedure. Presents step-by-step, side-by-side full-color illustrated guidance. Uses a standard chapter organization for quick reference. Offers a brief description of each procedure. Features bulleted lists of clinical indications, oft-overlooked contraindications, and potential complications. Displays the essential equipment needed to perform the procedure. And more.

The onset of the quadruple burden of disease in South Africa, the challenges faced by the medical establishment to curtail the rapid growth of multiple epidemics, the inadequate response by the state to various inequities in the health system, and the public debates associated with it, have all combined to draw attention to the sociological aspects of health and disease. Sociology as a resource of knowledge and a unique analytical and conceptual perspective can be used to understand, explain and positively influence the course of health and disease in South African society and our responses to it. As a health practitioner or scholar you must be equipped with the skills to critically evaluate research and debates in your profession, be able to adapt to changes and contribute to the development of knowledge and best practice. This reader will familiarise you with relevant content and assist you to develop the analytical capacity and conceptual skills you will need. Society, Health and Disease in South Africa is authored by experienced educators and researchers in the fi elds of sociology, social work, anthropology, healthcare policy and practice.

Here is the Fourth Edition of the classic text Electrodiagnosis in Diseases of Nerve and Muscle. With each subsequent edition, Dr. Kimura has built upon his extensive experience teaching electromyography (EMG) around the world and has transferred his knowledge to the book. It is intended for clinicians who perform electrodiagnostic procedures as an extension of their clinical examination, and will be of value to neurologists and physiatrists who are interested in neuromuscular disorders and noninvasive electrodiagnostic methods, particularly those practicing electromyography (EMG). The book provides a comprehensive review of most peripheral nerve and muscle diseases, including specific techniques and locations for performing each test. While the book has been thoroughly updated to reflect the growth that has been made in the field since 2001, a DVD has also been added to the book, allowing the readers to watch and listen to various types of normal and abnormal EMG activities. The book is designed for those interested in a broad review of electrodiagnostic medicine, especially to those dealing with patients with neuromuscular disorders, who may benefit from a referral for electromyography and nerve conduction studies as part of the clinical practice. It will appeal to those wanting a current update on the subject and those interested in state of the art information and observation of electrophysiologic techniques.

Tending Adam's Garden describes and explains the way in which our immune system works from a novel perspective. The book uses metaphors and examples to bring the immune system to life and explores the fundamental miracle of nature. Written in plain language for a broad audience, this book encompasses much more than just immunology, exploring more fundamental matters such as causality, information, energy, evolution, cognition and individuality, as well as the strategy of the immune system and its role in health and disease.
* Provides a unique perspective on the immune system from one of the keenest scientific and philosophical brains in the world
* Uses metaphors and case histories to explore themes in an accessible manner
* Written in plain language requiring no specialized vocabulary or specific scientific background in the subject

This is a comprehensive text on psychology as related directly to the physical and manual therapies. It is divided into 3 sections :Section 1 addresses psychological principles as they relate to illness, injury, and rehabilitation. Section 2 covers key concepts relevant to psychological care in the physical therapies (e.g., client-practitioner relationships, cognitive-behavioural interventions). The emphasis in the section is on integrating psychological and physical approaches to client care. Section 3 addresses specific client conditions encountered by those working in the physical and manual therapies. Easy-to-read style and format make the text a helpful reference for experienced practitioners brushing up, or for newcomers seeing a condition for the first time. Information effectively relates the theoretical and research foundation to the practicalities of client -practitioner relationships, interventions and working with clients with a variety of conditions. Broad international range of contributors provides diverse approaches, giving a global picture.

The authors of this book argue that there is a great divide between species that makes extrapolation of biochemical research from one group to another utterly invalid. In their previous book, "Sacred Cows and Golden Geese: The Human Cost of Experiments on Animals", the Greeks showed how an amorphous but insidious network of drug manufacturers, researchers dependent on government grants to earn their living, even cage-manufacurers - among others benefiting from "white-coat welfare" - have perpetuated animal research in spite of its total unpredictability when applied to humans. (Cancer in mice, for example, has long been cured. Chimps live long and relatively healthy lives with AIDS. There is no animal form of Alzheimer's disease.) In doing so, the Greeks aimed to blow the lid off the "specious science" we have been culturally conditioned to accept. Taking these revelations one step further, this book uses accessible language to provide the scientific underpinning for the Greeks' philosophy of "do no harm to any animal, human or not," by examining paediatrics, diseases of the brain, new surgical techniques, in vitro research, the Human Genome and Proteome Projects, an array of scien

Kinesiology is the study of human and nonhuman animal-body movements, performance, and function by applying the sciences of biomechanics, anatomy, physiology, psychology, and neuroscience. This book is a guide to human kinesiology for physiotherapists. Divided into three sections, the text begins with an introduction to the field, anatomical and physiological fundamentals of human motion, and biomechanics. The following section covers joint and muscle movement in different regions of the body, from shoulder, elbow, hand and wrist, to pelvis, hip, knee, ankle and foot, and spine. The final chapters discuss posture and movement and the application of kinesiology to daily life activities, sports skills and prevention of sports injuries. The comprehensive text is further enhanced by clinical photographs, illustrations and tables. Key points Comprehensive guide to human kinesiology for physiotherapists Provides clear understanding of anatomy, physiology and biomechanics Covers joint and muscle movement in all regions of the body Discusses application of kinesiology to daily life activities, sports and prevention of injuries

This book focuses specifically on the importance of managing and supporting people in health care services. Human resources are the most significant aspect of health care budgets and the attraction and retention of quality staff remains a pressing concern. This book addresses this issue directly and provides both a theoretical framework and extensive practical guidance in this vital aspect of health care management.Up-to date information on the context of health services today and the business agenda Relevant - Specifically aimed at nurses and nursing Practical - readers reflect on real life examples to see how they can use their skills in practice

This is a text which provides a contemporary approach to the use of lifestyle, herbal and nutritional interventions in health care. While conventional health care has long classified many nutritional and herbal remedies as folklore, there is increasing scientific evidence to support a number of 'old wives tales'. This book demonstrates the biological plausibility of using supplements in clinical care and supports the scientific validity of such interventions by referring to clinical trials. It provides the health professional with therapeutic protocols that can be used to manage or support other treatment regimes in promoting health, preventing and treating disease. The book is divided in to 3 parts. Part 1 considers the principles of nutritional intervention. Part 2 list prevalent diseases and provides a therapeutic protocol for their management. Part 3 lists nutrients (and some frequently used herbs) and seeks to catalogue the indications, doses, interactions and side effects that require consideration when providing safe and effective clinical care. The text will provide readers with:A grasp of how natural measures can be incorporated into scientifically acceptable clinical practice An understanding of the biological plausibility underlying the use of certain natural interventions in disease An appreciation of the level of scientific validation supporting various natural interventions Enhanced understanding of guidelines for the safe use of nutrients Therapeutic protocols using lifestyle, nutritional and herbal intervention for the prevention and management of various conditions. Increased awareness of natural options that deserve trialing in particular clinical situations

A combination of population growth, public health failures, environmental degradation and rapid global transportation has resulted in a world that is at increasing risk to vectorborne and other infectious diseases. A large percentage of emerging diseases are vectorborne and over one-third of the agents on the list of greatest concern from bioterrorism are vectorborne. Many of these diseases are viral that have no effective drug or vaccine treatments. Drug and insecticide resistance is now common and has greatly compromised our ability to provide effective and affordable control. Parasitic diseases, including malaria, leishmmaniasis and African trypanosomiasis are likewise increasing in many parts of the world. Control programs for onchocerciasis and to some extent filariasis are reducing the impact of these diseases, largely due to the availability of filaricides such as ivermectin. Chagas disease has also declined significantly through home improvements and indoor insecticide application against the domicilary kissing bug vectors.
Despite these gains, this tend has not been sustainable. Instead, infectious disease is now responsible for greater than 25% of all deaths and nearly 50% of premature deaths among those under 45 years of age, and 63% for children less than 4 years of age. A significant proportion of these deaths is attributed to vectorborne diseases, particularly from malaria ( 11%). Indeed, more that 1 million people are killed annually by malaria, about 3000 per day. It is estimated that 700,000 children under the age of 5 die of malaria and at least 300 million are ill due to malaria each year. In response, the American Institute of Medicine (2003) has called for a renewed effort to rebuild public health infrastructures needed to conduct disease surveillance and vector control programs and to increase research to provide improved pesticides and their use, new repellents, new biopestcides and biocontrol agents to augment pesticidal control, as well as novel strategies to interrupt pathogen transmission.
With these goals in mind, we convened the first vector control symposium as part of the scientific program of the 3rd Pan-Pacific Conference of Pesticide Science in 2003. Five years after (2008), we re-convened this expanded topic at the 4th Pan-Pacific Conference on Pesticide Science and the scientific presentations made over two days comprise this current volume, Advances in Human Vector Control. The book covers two major areas: 1) Current Status and Control Practices, covering malaria, dengue, Chagas, human lice, cockroach and house dust mite issues; and 2) Novel Approaches and Resistance Management of these diseases. Chapters are provided by internationally-recognized experts who are actively involved in vector control and management, providing an up to date summary of this critically important area of public health. The effective use of novel control strategies is stressed and the status of recently acquired genomic approaches is critically reviewed.

This manual encompasses a comprehensive approach to the management of labour. Based on the simple proposition that effective uterine action is the key to normal delivery, Active Management of Labour covers all aspects of delivery for nulliparous women with vertex presentation and single foetus. This is an accessible and practical guide for obstericians and midwives as well as anaesthetists and the auxiliary staff of maternity units. Encourages an active interest in labour by all professional staff Emphasises the importance of constant personal attention and good communication in labour Discusses in detail the need to distinguish between: - first and subsequent births - single cephalic and all other pregnancies - induction and acceleration of labour Fosters the development of a team spirit between midwife and obstetrician Demonstrates how good labour ward organisation can improve care Proves the importance of audit in ensuring quality of care Updated chapters on dystocia and caesarean section New key points summary at the end of each chapter Updated review of clinical outcomes at the National Maternity Hospital

* What is addiction?* How do you know if someone is addicted?* Are some people more prone to addiction than others?* Are some drugs more addictive than others?* How can you help someone who doesn't want help? Understanding Drugs of Abuse is designed to bring the everyday reader face-to-face with drugs of abuse and addiction. Through frank, no-nonsense explanations of the stimulants, depressants, psychedelics, and inhalants, this accessible guide will help the reader to understand how drugs of abuse affect thinking, behavior, perceptions, and emotions. It also examines the effects addiction has on the addict's family. Understanding Drugs of Abuse demystifies the treatment process by explaining what types of treatment are available, what actually happens during treatment, and what patients and their families can expect during the treatment process. The book also describes the recovery process and will help people identify good recovery-as well as recognize poor recovery and the warning signs of relapse. Perhaps most important, Understanding Drugs of Abuse explains how friends and family can intervene when someone they love does not want help. Because the use of prescribed medications by people with substance use disorders can be misunderstood or even be dangerous, this book presents practical information about medications and recovery. It also explores the unique problems of adolescents who are addicted, as well as people with the dual disorders of a psychiatric and substance use disorder. Understanding Drugs of Abuse will also help the reader understand the role of genetics and other influences on addiction to alcohol, the most widely abused drug of all.

This introductory textbook of pharmacoeconomics is ideal for all those working in, aspiring to work in or interested in the pharmaceutical industry. It assumes no prior knowledge of this subject but is written at a level appropriate, for example, for those studying for a postgraduate degree or diploma in pharmaceutical medicine and who already have a first degree in science or medicine. Emphasizes how pharmacoeconomics can be of assistance in "real world" decision making. Covers the development of insuring, financing and delivery of health care in the developed world and the increasing role of governments. Explains the trend towards the critical scrutiny of health service activity. All topics explained assuming no specialist knowledge.