MRI of the Elbow and Wrist is explored in this important issue in MRI Clinics of North America. Articles include: Approach to MRI of the Elbow and Wrist: Technical Aspects and Innovation; MRI of the Elbow; Extrinsic and Intrinsic Ligaments of the Wrist; MRI of the Triangular Fibrocartilage Complex; Carpal Fractures; MRI of Tumors of the Upper Extremity; MRI of the Nerves of the Upper Extremity: Elbow to Wrist; MR Arthrography of the Wrist and Elbow; MRI of the Wrist and Elbow: What the Hand Surgeon Needs to Know; Imaging the Proximal and Distal Radioulnar Joints; MR Angiography of the Upper Extremity, and more!

Early identification and diagnosis by type and stage is the key to high survival rates with thyroid cancer. To present the pathologist with current clinical information on diagnosis, differential diagnosis, staging, and prognosis of thyroid cancers, topics presented are: Poorly differentiated thyroid carcinoma; Paraganglimoa; Immunohistochemical markers for evaluation and prognosis in thyroid carcinoma; Familial endocrine syndromes; Parathyroid enoplasia; Inflammatory lesions of the thyroid associated with cancer; Assessing biological aggression in adrenal cortical neoplasia; Pituitary neoplasia; and Pancreatic endocrine neoplasia. Peter Sadow, whose clinical practice and research involve studying the mechanisms of endocrine carcinogenesis through translational studies involving the proteomics and genomics of endocrine neoplasms, primarily of the thyroid and adrenal glands, leads this issue.

This issue of Clinics in Geriatric Medicine is devoted to Nutrition in Older Adults. Guest Editor John E. Morley, MD has assembled a group of expert authors to review the following topics: Anorexia of Aging; Protein and Older Persons; Screening for Malnutrition in Older People; Obesity and Aging; Vitamins; Sarcopenia; Diabetes: Nutrition and Exercise; Frailty, Exercise and Nutrition; Dehydration; Cholesterol and Older Persons; Cognition and Nutrition; and Gastric Emptying in the Elderly.

This issue of Clinics in Geriatric Medicine, devoted to Geriatric Oncology, is guest edited by Drs. Harvey J. Cohen and Arati V. Rao of Duke University Medical Center. Articles in this issue include: Cancer and Aging: General Principles, Biology and Geriatric Assessment; Cancer Screening in the Elderly; Cancer Survivorship: Management of Long-term Toxicities; Socioeconomic Considerations and Shared Care Models of Older Cancer Care; Palliative Care and Symptom Management; Management of Prostate Cancer in the Elderly; Management of Breast Cancer in the Elderly; Management of Lung Cancer in the Elderly; Colorectal Cancer in the Elderly; Myelodysplastic Syndrome and Acute Myeloid Leukemia in the Elderly; Chronic Lymphocytic Leukemia and Other Lymphoproliferative Disorders; and Monoclonal Gammopathies and Multiple Myeloma in the Elderly.

Repair and restoration of the facial nerve takes exceptional skill in facial anatomy and surgery. In this issue of Facial Plastic Surgery Clinics, surgeon and academician Daniel Alam leads discussion by expert surgeons of topics such as Bell's Palsy, Botox in the treatment of facial paralysis; Management of the eye in facial paralysis; Static slings; Temporalis tendon transfer; Nerve transfer; Gracilis flaps; Sternohyoid flaps, New technologies in facial paralysis; and Physical therapy for facial rehabilitation. Each discussion includes diagnosis and procedural steps for best outcomes for function and cosmesis.

This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Douglas L. Fraker, is devoted to Endocrine Tumors. Dr. Fraker has assembled expert authors to review the following topics: Management of thyroid nodular disease: Current cytopathology classifications and genetic testing; Surgical management of lymph node compartments in papillary thyroid cancer; Current guidelines for post-operative treatment and follow-up of well differentiated thyroid cancer; Outpatient thyroid surgery - is it safe?; Asymptomatic hyperparathyroidism- diagnostic pitfalls and surgical intervention; Intra-operative PTH monitoring: optimal utilization; Minimally invasive parathyroidectomy vs bilateral neck exploration for primary hyperparathyroidism; Pheochromocytoma and paraganglioma: Diagnosis, genetics, and treatment; Minimally invasive adrenalectomy; Treatment of adrenocortical cancinoma: benefits of aggressive surgery; Biochemical diagnosis and pre-operative imaging of gastro-intestinal neuroendocrine tumors; Minimally invasive techniques for resection of pancreatic neuroendocrine tumors; and Treatment of metastatic neuroendocrine tumors to the liver.

Heart failure is the only cardiovascular disease that is increasing. The impact on the critical care environment and the health care system, as a whole, is significant from both a cost and burden to the system perspective. There are 6.5 million hospital days a year and nearly $40 billion dollars in yearly health care costs attributed to heart failure in the United States. There are more Medicare monies spent for diagnosing and treating heart failure than any other Diagnosis Related Group. There is a 24% hospital re-admission rate for this diagnosis which leads to financial implications for health care systems. The human cost is also significant. Less than half of Americans diagnosed with heart failure survive greater than 5 years. The ongoing health care needs and cost of this chronic disease takes a significant toll on patients' finances, time and quality of life. Over $2.9 billion dollars is spent annually on the pharmaceutical management of heart failure in the United States. This diagnosis is the leading cause of hospitalization for patients who are 65 years of age and older. Few health care providers in the critical care environment are not affected by heart failure on a routine basis. Caring for these patients and their families is both a challenging and yet a rewarding experience. This edition will provide critical care nurses with a comprehensive heart failure review which is essential in caring for this challenging population given the dynamic health and critical care environments.

The subtalar joint, also known as the talocalcaneal joint, is a joint of the foot. It occurs at the meeting point of the talus and the calcaneus.. This issue will include articles on Subtalar anatomy and mechanics, Subtalar arthritis, Subtalar arthrodesis, open and arthroscopic, indications and contraindications, Subtalar distraction arthrodesis and many more.

The Oregon State Insane Asylum was opened in Salem on October 23, 1883, and is one of the oldest continuously operated mental hospitals on the West Coast. In 1913, the name was changed to the Oregon State Hospital (OSH). The history of OSH parallels the development and growth in psychiatric knowledge throughout the United States. Oregon was active in the field of electroshock treatments, lobotomies, and eugenics. At one point, in 1959, there were more than 3,600 patients living on the campus. The Oscar-winning movie One Flew Over the Cuckoo's Nest was filmed inside the hospital in 1972. In 2008, the entire campus was added to the National Register of Historic Places, and the state began a $360-million restoration project to bring the hospital to modern standards. The story of OSH is one of intrigue, scandal, recovery, and hope.

This issue provides much needed updates since Dr. Sheinfeld's issue published in 2007. Dr. Lin has assembled expert authors to provide clinicians with the full breadth of clinical updates on testicular cancer. New to this issue are articles on clinical outcomes, survivorship, and several articles on the management of Nonseminomatous Germ Cell Tumors.

This issue of Heart Failure Clinics examines the critical role of team-based care in the management of patients with heart failure. Articles address Team-Based Care for Prevention, Patients Hospitalized with Heart Failure, Transitions of Care, Outpatients, Managing Cardiac Comorbidities, Managing Non-cardiac Conditions, Cardiac Rehabilitation and Exercise Training, External Telemonitoring, Ambulatory Hemodynamic Cardiac Device Monitoring, Advanced Heart Failure, and Palliative and End-of-Life Care.

Drs. Richard Carlson and Corey Scurlock have put together a cutting edge list of topics regarding the use of Telemedicine in the Intensive Care Unit. Topics include: Tele-Neurocritical Care, Outcomes related to Telemedicine in the ICU,Telemedicine in the ICU: Its role in Emergencies and Disaster Management,Increasing Quality through Telemedicine in the ICU,The Role of Telemedicine in Pediatric Critical Care,Telemedicine and the Septic Patient,Taking Care of the Cardiac Critical Care Patient with Telemedicine,Barriers to ICU telemedicine,and Design and Function of Tele-ICU.

This issue of Dental Clinics, edited by Harry Dym, focuses on Implant Procedures for the General Dentist. Articles will include: Basic principles of implant surgery, Maxillary sinus augmentation techniques, Surgical techniques for augmentation in the horizontally and vertically compromised alveolus, Autologous bone harvest sites, Bone morphogenic protein and its application to implant dentistry, Soft tissue augmentation for implant surgery, Immediate placement and immediate loading: Surgical technique and clinical pearls, Treatment of peri-implantitis and the failing implant, Implant related nerve injury, All on four techniques, CT-guided implant surgery, Short implants: Are they a viable option in implant dentistry?, Treatment planning for implant surgery, Surface material, implant design and osseointegration, Tissue response to implants, and more!

Community-based primary care physicians are routinely challenged as they stabilize, evaluate, and care for term and late-preterm neonates. Although there have been many spectacular advances in care of neonates, the challenges and successes of caring for the most preterm, very low birth-weight newborns seem to dominate presentations and the Pediatric literature. This issue concentrates on the current evidence and the collected experience of neonatologists regarding the basics of caring for the vast majority of newborns. The newest recommendations of multiple organizations (including the AAP) are presented, including the rationale for each recommendation as well as controversial issues. The individual articles will provide the primary care provider with a comprehensive foundation for care of the neonate.

This issue of Clinics in Plastic Surgery offers the plastic surgeon (and facial plastic surgeon, reconstructive surgeon, burn surgeon, any surgeon working with face or body reconstruction or rejuvenation) an intensive review of all aspects of working with fat. The title succinctly sums it up that clinical applications, currently known concepts, and future expectations of working with fat for reconstructive or cosmetic surgery are presented here. The Editors and their selected are peerless in the field that focuses on biology of fat, adipose derived stem cells, and growth factors; harvesting, processing, and storage of harvested fat; how to maximize the results of fat grafting; and safety issues with fat grafting and growth factors. Practical clinical applications, currently known concepts, and future expectations of working with fat for reconstructive or cosmetic surgery are presented here. Because of the depth and comprehensiveness of the material presented by the experts in this field, this issues is presented in two parts; Part 1 topics include: Adipose Tissue and Stem/Progenitor Cells: Discovcery and Development; Cryopreservation of Adipose Tissue and Adipose Derived Stem Cells; Adipose Stem Cells: Biology, Safety, Regulation, and Regenerative Potential; History and Development of Fat Grafting: from Ram Fat to Stem Cells; Condensation of Tissue and Stem Cells for Fat Grafting; Can We STtandardize the Techniques for Fat Grafting; How Fat Survives and Remodels after Grafting; The Role of Fat Grafting in Facial Rejuvenation; Gluteal Augmentation with Fat Grafting-the "Brazilian Buttock Technique:" 30 Years' Experience; Fat Grafting for Treatment of Burns, Burn Scars, and other Difficult Wounds.

This issue will focus on sports-related foot and ankle injuries, including articles on the following: Podiatrists as a member of the sports medicine team, New & emerging sports medicine technologies, Ankle sprains and return to sports activities, Dynamic clinical assessment techniques of the athlete, Acute lower extremity injuries, Principles of rehabilitation and return to sports following injury, and many more!

This issue is the third issue Dr. John Calamia and colleagues have edited on cosmetic dentistry. This issue, titled "Modern Concepts in Aesthetic Dentistry & Multi-disciplined Reconstructive Grand Rounds," features 20 articles on Smile design, Proportional smile design, Use of Kois analyzer in the restoration of anterior dentition, Cements and adhesives for all-ceramic restorations, Replacement of old PFM crowns with all ceramic restorations, Cosmetic makeover insuring patient input, Orthodontic intervention: diastema closure, Fluorosis, chemical abrasion, and porcelain veneers, Aesthetic smile enhancement, Treatment of intrinsic stains, Moderate mandibular anterior crowding, Functional and aesthetic rehabilitation, Restoration of the anterior segment, Full mouth reconstruction of worn dentition, Interdisciplinary aesthetic treatment, Gummy smile reduction, Diastema closure, and much more!

This issue will discuss the techniques for various osteotomies of the foot and ankle. Articles included are: Osteotomies of the first ray for hallux abductovalgus correction, Central metatarsal osteotomies for deformity correction, Osteotomies of the fifth metatarsal, Minimal invasive surgery osteotomies for the forefoot/midfoot, Minimal invasive surgery osteotomies of hind foot/ankle, Corrective osteotomies used in pes planovalgus reconstruction, and many more!

This issue provideds a comprehensive update to Sleep Medicine in the Intensive Care Unit, with editors Vipin Malik and Teofilo Lee-Chiong assembling a line-up of key topics such as:Sleep Neurobiology and Critical Care Illness,Obesity Hypoventilation Syndrome and Respiratory Failure,Obstructive Sleep Apnea,Non-Invasive Ventilation in Critically Ill Patients,Restless Leg Syndrome,Sleep and Endocrine System,Congestive Heart Failure and Central Sleep Apnea,Circadian Dysrhythmias,Neuromuscular Disorders and Sleep in Critically Ill Patients, Perioperative Issues and Sleep Disordered Breathing, Seizures, and more!

TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use is authored by experts across academia and industry, providing readers with a complete picture of the therapeutic potential and challenges associated with using TRP channels as drug targets. This book offers a unique clinical approach by covering compounds that target TRP channels in pre-clinical and clinical phases, also offering a discussion of TRP channels as biomarkers. An entire section is devoted to the novel and innovative uses of these channels across a variety of diseases, offering strategies that can be used to overcome the adverse effects of first generation TRPV1 antagonists. Intended for all researchers and clinicians working toward the development of successful drugs targeting TRP channels, this book is an essential resource chocked full of the latest clinical data and findings.

Each issue of Orthopedic Clinics offers clinical review articles on the most cutting edge technologies, techniques, and more in the field. Major topic areas include: adult reconstruction, upper extremity, pediatrics, trauma, oncology, hand, foot & ankle, and sports medicine.

Written by recognized dental implant surgery experts Marco Rinaldi, Scott Ganz, and Angelo Mottola, Computer-Guided Applications for Dental Implants, Bone Grafting, and Reconstructive Surgery is the first text to provide state-of-the-art information on procedures and techniques used in guided dental implant surgery and bone grafting. It begins with the basic principles of guided dental implants including anatomical obstacles, pathologies, and pharmacological management of patients, and then uses a templated, atlas format to discuss clinical case studies. With a companion website includes videos demonstrating surgical procedures, this text makes it easier for the entire surgical team to share in the diagnosis and treatment planning for patients receiving implants. Coverage of computer-guided surgery from treatment planning to recovery includes a combination of actual 3-D computed imagery and clinical photos to clearly demonstrate implant surgeries. Bone grafting protocols address 3-D evaluation of bone density and the use of bone grafts to augment bone volume prior to dental implant surgery. 40 case studies include pre- and post-operative considerations as well as the description of the surgical procedure, using high-quality clinical photos as well as CT and 3-D images to clearly illustrate every guided-implant challenge. Over 1,800 full-color images include pre-, intra-, and post-operative photographs, showing pathologies, procedures, and outcomes. Expert, authoritative authors provide guidance based upon extensive experience with current techniques as well as the latest technological advances in guided-implant surgery. A companion website includes 10 video clips that are linked to selected clinical cases in the text. Digital book formats supplement the print book, making this reference easy to access on iPads, tablets, e-readers, and smart phones.

This exciting issue will cover everything from Ligament anatomy and biomechanics of the Carpus, Diagnosis and Treatment of Perilunate and lunate fracture/dislocations, Acute Scapholunate ligament injuries - arthroscopic treatment, Acute scapholunate ligament injuries - open treatment, Diagnosis and treatment of acute lunotriquetral ligament injuries to Management of intercarpal ligament injuries associated with distal radius fractures, Chronic scapholunate ligament injuries - soft-tissue ligament reconstruction , Midcarpal instability, Salvage procedures in the management of carpal instability, and many more.

Upper gastrointestinal bleeding is the leading emergency leading to hospitalization and urgent endoscopy. The field of gastrointestinal bleeding is rapidly evolving. The epidemiology is changing with more complex older patients on anticoagulant and antithrombotic agents presenting with upper gastrointestinal bleeding. The initial management has rapidly evolved with new transfusion thresholds, the use of risk stratification scores and no more nasogastric tubes. There is new data and recommendations on optimal timing of endoscopy. Medical therapies have also evolved with changes in proton pump inhibitor administration and the use of prokinetics to improve endoscopic visualization. Many modifications in endoscopic therapy have recently been advanced including the use of endoscopic ultrasound guided angiotherapy, topical sprays (i.e. Hemospray) and over-the-scope clips. In order to give optimal care to patients, it is critical that practicing gastroenterologists are aware of the many recent advances in management of patients with upper gastrointestinal bleeding.

Nervous system injuries, including peripheral nerve injuries, brain and spinal cord injuries, and stroke affect millions of people worldwide every year. As a result of this high incidence of neurological injuries, neural regeneration and repair is becoming a rapid growing field dedicated to the new discoveries to promote structural and functional recoveries based on neural regeneration. The ultimate goal is to translate most optimal regenerative strategies to treatments of human nervous system injuries. "

Neural Regeneration" provides an overview of cutting-edge knowledge on a broad spectrum of neural regeneration, including 1) neural regeneration in lower vertebrates, 2) neural regeneration in the peripheral nervous system, 3) neural regeneration in the central nervous system, 4) transplantation-mediated neural regeneration, and 5) clinical and translational research on neural regeneration. The contributors of this book are experts in each of their respective fields and are highly international including scientists working at different institutions in the United States, Canada, Australia and China.

This valuable reference book will be useful for students, postdoctors, and basic and clinical scientists who are interested in neural regeneration research.
Provide an overview of cutting-edge knowledge on a broad spectrum of neural regeneration. Highly translational and clinically-relevanceInternational authors who are leaders in their respective fieldsVivid art work making the chapters easily understood