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This book provides detailed information on the emerging applications of nanomaterials and nanoparticles within endodontics, highlighting the exciting potential clinical impact of nanotechnology in the field. The range of applications covered is diverse, encompassing drug and gene delivery, tissue engineering, antibacterial strategies, dentin tissue stabilization, dentin pulp regeneration and use in restorative and endodontic materials. Important scientific background information relating to each application is provided, with clear coverage of basic principles. In addition, potential pitfalls are identified and explained. The cytotoxicity of nanomaterials and nanoparticles is also addressed in a separate chapter. The book will be of value both for endodontic practitioners and for all scientists and graduate students who are interested in the application of nanotechnology in endodontics.
The year 1818 saw the publication of one of the most influential science-fiction stories of all time. Frankenstein: Or, Modern Prometheus by Mary Shelley had a huge impact on gothic horror and science-fiction genres, and her creation has become part of our everyday culture, from cartoons to Hallowe'en costumes. Even the name `Frankenstein' has become a by-word for evil scientists and dangerous experiments. How did a teenager with no formal education come up with the idea for an extraordinary novel such as Frankenstein? Clues are dotted throughout Georgian science and popular culture. The years before the book's publication saw huge advances in our understanding of the natural sciences, in areas such as electricity and physiology, for example. Sensational science demonstrations caught the imagination of the general public, while the newspapers were full of lurid tales of murderers and resurrectionists. Making the Monster explores the scientific background behind Mary Shelley's book. Is there any science fact behind the science fiction? And how might a real-life Victor Frankenstein have gone about creating his monster? From tales of volcanic eruptions, artificial life and chemical revolutions, to experimental surgery, 'monsters' and electrical experiments on human cadavers, Kathryn Harkup examines the science and scientists that influenced Shelley, and inspired her most famous creation.
Choosing an uncemented femoral prosthesis means first choosing a concept and to be effective, an operator has to have access to all the information that will allow them to reach the desired goals. This is the first step to be made.
The quality of a surgical procedure does not depend on the manual skills of the surgeon performing it, but on how he has prepared and performed the operation virtually before actually performing it. This is the second step.
An operating technique must be adapted to the chosen concept and the purpose of every surgical procedure must be clearly formulated and understood by the operator. This is the third step.
Every surgeon has to have a reliable and rigorous radiological method of analysis for evaluating overall results and which suggests ways of improving results."
This book provides a comprehensive account of the pathogenesis, clinical features, and management of ocular vascular occlusive disorders, with the focus very much on the scientific evidence. This offers a sound basis for addressing the many controversies that surround these disorders, which collectively constitute the most common cause of visual impairment or blindness. The book is divided into two sections, the first of which addresses the basic science and encompasses vascular anatomy, blood supply and flow, and retinal tolerance time to acute ischemia. The second, clinical, section covers the presentation, clinical features, diagnosis, and treatment of the full range of vascular occlusive disorders of the retina, the choroid, the anterior segment of the eye, ophthalmic manifestations of carotid artery disease and the optic nerve. Ocular Vascular Occlusive Disorders, written by a distinguished world leader in the field, will be invaluable for general ophthalmologists, and particularly for retina specialists, neuro-ophthalmologists, and researchers.
There is increasing interest in using ultrasound for assessment of pelvic floor disorders such as voiding dysfunction , pelvic organ prolapse and faecal incontinence. Ultrasound can also be a useful imaging modality for urodynamics and pelvic floor physiotherapy. Whilst ultrasound equipment is widely available around the world many clinicians may not have access to structured training in the technique of pelvic floor imaging and interpretation of images in the context of pelvic floor dysfunction. This book aims to provide the reader with the knowledge and skills to start utilising ultrasound imaging in assessment of pelvic floor disorders. The authors comprise the three surgical disciplines (urology, colorectal surgery and gynaecology) who commonly manage pelvic floor problems and have subspecialty expertise in pelvic floor imaging. They have conducted workshops in Australia, Asia, UK and USA and are advocates for clinican-performed ultrasound.
This book is a quick reference guide to the new, more personalized approaches to the management of skin disorders that have emerged as a result of progress in our understanding of the genetic background and pathophysiology of skin diseases and the diversity of mechanisms underlying their clinical heterogeneity. A wide range of personalized and targeted therapies are described, including those for different skin cancers, chronic inflammatory skin diseases, and autoimmune diseases. In addition, readers will find that the book documents how research results in personalized medicine can be effectively transferred to dermatological practice and looks forward to future treatments that might be developed on the basis of recent research findings. The authors are all recognized experts in the field, and the text is presented in a reader-friendly format and well illustrated.
This handbook is a concise, easy-to-read, practical guide that conveys the core knowledge necessary to diagnose, classify, grade, and manage dry eye disease effectively and efficiently. A series of succinct, informative chapters cover the following key topics: definition and classification, epidemiology, office-based screening and diagnostics, artificial tears, medical management, surgical management, and future directions. Current guidelines, published studies, and the personal experience of internationally recognized dry eye experts are distilled into practical tips that will be of value during daily clinical routine. Highlighted boxes are included to emphasize the most important points or clinical pearls, and tables and flow charts will further assist the eye care practitioner in using the book as a quick reference. The closing chapter presents case examples that build upon the instruction provided earlier in the book by illustrating the optimal approach to diverse scenarios that may be encountered in the clinic.
An exhilarating insight into the life of a doctor at Heathrow Airport, where the truth is often stranger than fiction. For over a decade, Stephanie Green was a doctor on-call for one of the world's busiest airports, confronting dramatic, bizarre and sometimes heart-breaking situations. During her 24-hour shifts at Heathrow, Dr Green had to be ready for anything: from finding an abandoned suitcase leaking blood onto the carousel, to discovering a man smuggling heroin in a corset. It's a job that brought her into contact with all walks of life; her patients included drug mules and fugitives, schizophrenics and stowaways, refugees and tourists. And with the threats of a nerve agent poisoning or a Level Four viral epidemic always in the back of her mind, Dr Green found herself on the frontline where the decisions are made about who - or what - was allowed to leave the airport's borders. FLIGHT RISK reveals the thrilling drama that takes place behind-the-scenes of an airport and what is needed to make critical decisions in this hidden no-man's land of geopolitics, terror, tragedy and medicine.
Reproduction is a fundamental feature of life, it is the way life persists across the ages. This book offers new, wider vistas on this fundamental biological phenomenon, exploring how it works through the whole tree of life. It explores facets such as asexual reproduction, parthenogenesis, sex determination and reproductive investment, with a taxonomic coverage extended over all the main groups - animals, plants including 'algae', fungi, protists and bacteria. It collates into one volume perspectives from varied disciplines - including zoology, botany, microbiology, genetics, cell biology, developmental biology, evolutionary biology, animal and plant physiology, and ethology - integrating information into a common language. Crucially, the book aims to identify the commonalties among reproductive phenomena, while demonstrating the diversity even amongst closely related taxa. Its integrated approach makes this a valuable reference book for students and researchers, as well as an effective entry point for deeper study on specific topics.
This clinical case book serves as a useful guide for dermatologists, internists, family practitioners, pediatricians, and anyone else charged with the care of infectious diseases of the skin of parasitic, fungal, bacterial, and viral origin. The case-based format distinguishes this work from a reference-style textbook, allowing readers to relate the presented cases to their own practice. Clinical Cases in Infections and Infestations of the Skin provides help and insight for clinicians in managing skin disease, with each chapter serving as a springboard for further pursuit and more extensive training. The reader will find useful information and tools to help patients and will enable readers to add to their current clinical regimens by becoming familiar with healing systems beyond medical dermatology. The book will enable those new to the field to develop a literacy and competence in the management of infectious dermatology. For the more experienced learner, it will assist in finding new ways to sharpen diagnostic and treatment acumens.
This book provides wide-ranging information on the progress achieved in the diagnosis, treatment and management of dentine hypersensitivity during the past few years. Recent advances in research, including innovations in the development of desensitizing agents, are fully described and detailed attention is paid to novel clinical approaches and potential future strategies in product development. Introductory chapters cover important aspects of physiology, prevalence and aetiology and advances in diagnosis and in vitro testing techniques for dentine hypersensitivity are discussed. Dentine hypersensitivity is a troublesome clinical condition that continues to perplex the clinician despite the vast array of available treatments that have been formulated to resolve the problem. There continues to be under-reporting of the condition by clinicians and uncertainty over aetiology, diagnosis and effective management. This book will hopefully contribute in combating these deficiencies and assist the clinician in delivering optimal patient care.
This book provides the reader with an up-to-date, practical and succinct overview of basic neuropathology. It does not replace large reference textbooks in neuropathology but emphasizes key concepts and basic principles including recent advances, genetics and classification, and discusses important aspects of specific neuropathological disorders. It also gives practical hints on aspects of neuropathology, including how to best use the neuropathology service and interpret the results of pathological tests. The reader will gain a sufficiently broad basic knowledge of neuropathology which will be of use in their future clinical careers. Neuropathology Simplified is aimed at trainees and residents in neurology, neurosurgery and psychiatry around the world. It may also be of use to basic scientists involved in neuroscience research and also to general histopathology trainees and residents.
This is an outstanding book. Murphy has done the cancer community a vital service.--Library Journal
Provides a valuable resource for young women. Combining anecdotes from breast cancer patients who have undergone treatment with emerging scientific research, Murphy has compiled a clear and nonjudgmental guide to negotiating treatment and living with the illness.--Publishers Weekly
This book reviews the imaging features associated with selected classes of pharmaceuticals and drugs on brain, head and neck, and spine and explains the implications of the imaging findings for the neuroradiologist and the clinician. Some agents produce characteristic abnormalities with distinctive imaging features, while others have a spectrum of manifestations on imaging. Still further agents produce rather nonspecific changes on imaging, requiring a differential diagnosis. In this book, informative cases are depicted by rich images, with concise accompanying explanatory text that reviews the class of agent and the mechanism of action and discusses image interpretation and its significance.
This compact book provides step-by-step guidance in the approaches and techniques developed and currently used at the authors' center in Dusseldorf for the treatment of a variety of aneurysms. All of the described procedures are minimally invasive and of proven efficacy. In order to assist the reader in fully comprehending all aspects of the techniques, they are illustrated through clear graphics instead of complex photos and radiologic imaging. While the rapid development of endovascular treatment means that it is no longer necessary to employ microsurgery for difficult and hidden aneurysms, proficiency in microsurgery remains essential. For example, full mastery of microsurgical techniques is vital in order to treat middle cerebral and peripheral aneurysms efficiently and with minimal trauma. Minimal invasiveness and optimal cosmetic results have become critically important in enabling the microsurgical method to compete with the endovascular method. In documenting "tried and tested" procedures, this book will be invaluable for both established neurosurgeons and residents in neurosurgery.
This book provides the practitioner with a framework for establishing a diagnosis and developing a suitable treatment plan in patients presenting with a range of developmental defects of the teeth. The conditions covered include failure of tooth eruption, hypodontia, premature tooth exfoliation, defects of enamel development, and defects of dentin development, with full consideration of both syndromic and non-syndromic defects. In each case the phenotype and genotype are first described, followed by diagnostic information, including the availability of genetic testing, and treatment options. Summarizing tables are used to highlight the key diagnostic features, and helpful illustrated case presentations are included. Cleft palate is also addressed, with details on etiology, phenotypes, treatment timing and approaches, and dental management. The closing chapter provides stimulating reflections on potential future directions in the diagnosis and treatment of these disorders.
This book reviews the progress made in salivary diagnostics during the past two decades and identifies the likely direction of future endeavors. After an introductory section describing the histological and anatomical features of the salivary glands and salivary function, salivary collection devices and diagnostic platforms are reviewed. The field of "salivaomics" is then considered in detail, covering, for example, proteomics, the peptidome, DNA and RNA analysis, biomarkers, and methods for biomarker discovery. Salivary diagnostics for oral and systemic diseases are thoroughly discussed, and the role of salivary gland tissue engineering for future diagnostics is explored. The book closes by considering legal issues and barriers to salivary diagnostic development. Advances in Salivary Diagnostics will be an informative and stimulating reference for both practitioners and students.
This book provides clear guidance on how to achieve excellent functional results and avoid failures when performing cystectomy and orthotopic bladder substitution. The opening sections present helpful checklists relating to patient selection, preoperative management, the procedures themselves, intraoperative measures, postoperative management, and actions to be taken in the event of various symptoms and complications. The remainder of the book focuses in detail on a variety of specific points of interest such as how and why to attempt a nerve-sparing cystectomy, the role of pelvic lymph node dissection, physical and physiological considerations relevant to reservoir construction, metabolic consequences of the incorporation of bowel into the urinary tract, preservation of renal function, and quality of life issues. The information provided may not only be instrumental to urologists, but also to specialized health care professionals, as well as the concerned patients.
*Interested in purchasing The Art and Science of Mental Health Nursing as a SmartBook? Visit https://connect2.mheducation.com/join/?c=normanryrie4e to register for access today* This well-established textbook is a must-buy for all mental health nursing students and nurses in registered practice. Comprehensive and broad, it explores how mental health nursing has a positive impact on the lives of people with mental health difficulties. Several features help you get the most out of each chapter and apply theory to practice, including: * Personal Stories: Provide insight into the experience of mental health difficulties from the perspective of service users and their carers * Thinking Spaces: Help you reflect on your practice and assess your learning individually and in groups, with further guidance available online * Recommended Resources: Provide additional materials and support to help extend your learning New to this edition: With four brand new chapters plus nine chapters re-written by original authors, key developments in this edition include: * Physical health care of people with mental health problems * Care of people who experience trauma * Promoting mental health and well-being * Support needed by nurses to provide therapeutic care and to derive satisfaction from their work * Innovations in mental health practice `The newly revised and updated edition has continued to offer an intelligent and readable text that offers a great deal to both students and those undertaking continuous professional development ... This edition continues to offer "thinking spaces" that encourage the reader to reflect upon and consider what they have learned in a most practical way. I wholeheartedly recommend this book and continue to be impressed with its high standards of presentation and scholarship'. Emeritus Professor Tony Butterworth CBE, Chair, Foundation of Nursing Studies, Vice Chair RCN Foundation, UK `It is a pleasure to open this book and to see the comprehensive range of information and evidence based guidance in relation to effective practice in nursing. Even If you only buy one professional book this year make it this one!' Baroness Watkins of Tavistock; Crossbench Peer, PhD and RN (Adult and Mental Health), UK `The importance of the teaching within this book cannot be underestimated ... The book is written by credible and respected practitioners and will support mental health nurses to practice from the best evidence available today working from and with the human condition'. Beverley Murphy, Director of Nursing, South London and Maudsley NHS Foundation Trust
This book covers all aspects of body contouring with silicone implants with the exception of breast augmentation. After a discussion of the available silicone implants and anesthetic management, the various techniques that may be used in body sculpting are carefully described in a series of chapters focusing on augmentation of the biceps, triceps, pectorals, buttocks, hip/thigh, calf, and quadriceps. Potential complications are identified for each of the procedures and clear guidance is provided on how to avoid them. The book will enable the surgeon to gain a sound understanding of the different body sculpting techniques and when they are applicable. It is intended both for students/beginners and for experienced cosmetic plastic surgeons alike.
Female genital malformations represent miscellaneous deviations from normal anatomy. With a prevalence of approximately 6% in the general population, they might be associated with health problems, potentially dangerous complications or poor reproductive outcome depending on the type and the degree of the anatomical abnormality. During the last two decades the better understanding of their pathogenesis, the availability of new non-invasive techniques for their diagnosis and the increased experience from their treatment have radically changed their management. A new, clinically oriented classification system has now been developed facilitating their evidence-based appraisal. It is a reality that the management of female genital malformations has changed rapidly during the last few years from an experience based and mainly descriptive field to a scientific evidence-based one. This book presents all uterine, cervical and vaginal anomalies in a systematic way and the new ESHRE/ESGE classification system utilised for their categorization. In addition, their embryogenesis and etiology are summarized. The diagnostic work-up of women with female genital malformations is reviewed in an evidence-based fashion and taking into account the availability of new non-invasive diagnostic methods. The treatment strategy and the therapeutic alternatives to restore health and reproductive problems associated with their presence are critically reviewed.
This book examines in detail the current treatment options for first-line, relapsed, and refractory Hodgkin lymphoma and the management appropriate in special clinical circumstances, including in the elderly, pregnant women, and those with lymphocyte-predominant disease. Careful attention is devoted to the emerging individually tailored treatment strategies that are especially appealing given their potential to reduce early and late treatment side effects in this generally young patient population. In addition, clear guidance is provided on the management of Hodgkin survivors. Other topics addressed include epidemiology, pathogenesis, the role of the microenvironment, initial clinical evaluation, imaging diagnosis, use of staging systems, and prognostic factors. The second edition of Hodgkin Lymphoma: A Comprehensive Overview has been revised and updated by the key opinion leaders to reflect recent progress in the field. It will be of great value to hematologists, oncologists, and all others with an interest in Hodgkin lymphoma.
This monograph provides specialists and primary care physicians who are interested in hair with the practical know-how needed to achieve successful management of male alopecia. Guidance is first provided on the examination of hair loss in men, covering such aspects as clinical examination, the role of trichoscopy and the trichogram, laboratory work-up, and scalp biopsy. Diagnosis and treatment are then described in depth for a diverse range of conditions involving alopecia. Expert opinion is combined with the results of evidence-based medicine to provide the best current advice, highlighting the synergistic action of combination regimens and adjuvant treatments and explaining the concept of multitargeted treatment. All aspects of follow-up are covered, including compliance issues and expectation management. The role of hair care and cosmetics is also considered, with identification of potential adverse effects as well as benefits.
The new edition of this bestselling and trusted dictionary has been fully updated and revised to take account of recent developments in nursing practice and related fields. Updates to this edition cover many areas, with a particular focus on areas such as nutrition, medical research, lymphology, and critical care nursing. Written by medical and nursing specialists, and offering more than 10,300 clear and concise entries on the theory and practice of nursing, the dictionary provides comprehensive coverage of the ever-expanding vocabulary of the nursing professions. As well as nursing-specific terms, there are also many entries in the fields of medicine, anatomy, physiology, ethics, psychiatry, nutrition, statistics, and pharmacology. Almost 100 helpful illustrations and tables, and 17 appendices covering the Code of Conduct 2015, the calculation of drug dosages, essential skill clusters, religion and nursing practice, recommended alcohol intake, and much more, make this an essential reference tool for all nursing students and professionals.
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