Hospice care is one of the fastest-growing segments of the U. S. healthcare system, a trend that is expected to accelerate as the median age of the population continues to rise over the next three decades. Despite over forty percent of the population now dying while on hospice care, very little has been published on the ethical opportunities and challenges experienced in the everyday lives of those giving and receiving hospice care. This book is the first comprehensive collection devoted to analyzing distinctive ethical issues arising in the delivery of hospice care and designed to promote best ethical practices for hospice care professionals and organizations. Thirteen newly commissioned chapters by seventeen hospice experts populate three thematic sections of the book, each devoted to an aspect of the intersection between ethics and hospice care. Contributors have unique qualifications and abilities to articulate and respond to ethically significant phenomena that - while not always unique to hospice care - arise in especially poignant and complex ways when caring for patients enrolled in hospice. As the shift or return to home-based care at the end of life continues, hospice professionals and programs will be faced with a broader array of terminal illnesses, cultural beliefs and traditions, and patient and family values than ever before. Hospice will no longer be tailored solely to the final stage of cancer, but will need to accommodate patients whose illnesses are variable in their progression and whose treatment plans include many medical options. The ethical orientations and frameworks that have served hospice for the past 50 years will need to be supplemented and refined if hospice is to fulfill this changing social mission. Hospice Ethics explores a new paradigm for hospice ethics from a multi-disciplinary and provides an important educational resource for professional training in end of life care.

Some of the best clinical teaching happens during grand rounds, imaging conferences and the discussion of individual cases, but for ophthalmologists working in smaller centers, such opportunities can be infrequent. Handbook of Retinal Disease offers the benefit of a case discussion by describing retinal disorders through real-life examples, from a presenting problem through the differential diagnosis, an analysis of the imaging and other diagnostic results, to an outline treatment plan. The book features over 75 cases, each presented with a table of signs and symptoms to help with the differential diagnosis, questions to ask the patient and relevant imaging to order. Secondly, imaging results from relevant modalities are discussed, before a final diagnosis is put forward. The authors provide concise information on the diagnosis, including an outline of recommended treatments, follow-up and further reading. With its high quality images and highly structured, deductive approach, Handbook of Retinal Disease provides a clinically relevant guide to the latest imaging techniques used in the diagnosis of retinal diseases: OCT, colour and red fundus photography, fluorescein and indocyanine green angiography and fundus autofluorescence. Key Points Each case gives a structure for working up a differential diagnosis and treatment plan based on a challenging set of signs and symptoms Shows imaging results drawn from the full array of relevant, current imaging modalities Provides treatment plans tailored to each patient and reflecting the complex nature of some cases

No other neurological condition allows the same opportunities for an intracranial electrophysiological study of the human brain as epilepsy does. Epileptic surgery is designed to remove the epileptic focus from the human brain, thereby effecting either cure or substantial reduction of seizures in an individual with an otherwise intractable condition. Its use as a treatment modality dates from the late 19th century, and it has become a widely used treatment option throughout the world in the last 20-30 years. The complexity of epilepsy cases in surgical centres, and the need for invasive electrode studies for pre-surgical evaluation, are both greatly increasing. Invasive Studies of the Human Epileptic Brain is the definitive reference text on the use of invasive electroencephalographic (EEG) diagnostic studies in human epilepsy. Written by some of the most renowned epilepsy experts of the 20th and 21st centuries, the authors provide their expertise and insights into the identification and mapping of intracranial epileptiform and non-epileptiform activity, mapping of the human brain function, and approaches in the use of invasive electroencephalography in a variety of clinical situations. The book is organized into an easily readable series of chapters and is brilliantly illustrated with case studies; each providing an intuitively comprehensive approach to invasive brain studies.

Rehabilitation psychology is one of the fastest growing fields in applied psychology and involves the application of psychological knowledge and skills to the understanding and treatment of individuals with physical disabilities. Rehabilitation psychologists aim to optimize outcomes in terms of health, independence, and daily functioning while also minimizing secondary health problems. The Oxford Handbook of Rehabilitation Psychology provides background and overview of the associated psychological processes and types of interventions that are critical in managing the consequences of disability and chronic disease. Psychological models and research have much to contribute to those working with the physical disabilities; this volume has a broad cognitive behavioral focus within the general banner of the biopsychosocial framework. The editor has successfully brought together contributions from a range of well-established and experienced researchers and practitioners from a wide variety of clinical and academic contexts. They highlight the critical psychological aspects, review applied interventions, and consider the wider conceptual, clinical and professional themes associated with disability and society.

This book is a practical guide to the diagnosis and treatment of paediatric neurological disorders for trainee and practising paediatricians. Divided into four sections, the text begins with discussion on neurological evaluation including anatomy and imaging. The second section covers diagnostic techniques for different neurological disorders including seizures, neuromuscular weakness, autism and ADHD, and movement disorders. Section three presents a selection of clinical cases similar to those candidates may encounter in postgraduate examinations. The final section discusses therapeutic methods for a variety of neurological disorders. The comprehensive text is further enhanced by clinical photographs, tables, and flowcharts. Key points Comprehensive guide to diagnosis and management of paediatric neurological disorders Covers numerous conditions including seizures, movement disorders, and autism and ADHD Provides a selection of clinical cases for trainees preparing for examinations Highly illustrated with photographs, tables, and flowcharts

Maintaining the comprehensive coverage offered by the previous editions, this highly regarded text, now in its sixth edition and 32nd year of publication, is considered to be an indispensable resource for nurses and health care professionals engaged in the business of teaching and learning. Retaining the balance between theoretical issues and practical application, the text has been fully revised to reflect the most recent changes in nursing and nurse education including updated content on developments in teaching and learning, the introduction of the new NMC standards in the UK; developments in the NHS and the growing role of eLearning and technology.

The UK has a deservedly strong reputation for work on understanding social inequalities in health. But there is some way to go in ensuring that research and other types of knowledge are used to reduce inequalities in child health. This revised and updated edition of an important report looks at macro public policy interventions, community interventions, and individual level interventions in a variety of settings, and for a range of populations: infancy, early years, childhood and adolescence, and those with particular needs including looked after children. It considers 'what works' in practice. There are new case studies, updated research, and reference to cost effectiveness - particularly relevant for doing the right thing in a climate of austerity. Drawing on evidence from the UK and beyond, the book presents these in an accessible form not just for those who make decisions now, but also for the students of today who are the decision makers of tomorrow.

Headache: Through the Centuries illuminates the history of headaches with a particular interest in how the disorder has been understood and treated since the earliest recorded accounts, dating from around 4000 BC. Different types of headache were being recognized as early as the 2nd century AD. Over the years, though, the classification of types of headache has changed so that headache patterns described in the past are often difficult to relate to present-day types of headache. Since that time, a great deal of material on the topic has become available, the full gamut of manifestations of the disorder has been described, and considerable insight into its mechanisms has been obtained, though no completely satisfactory explanation of the disorder has yet become available. Providing an extensive history and the development of our understanding of headache over the course of six millennia, Headache: Through the Centuries is thought-provoking and relevant reading for neurologists, medical historians, and anyone interested in headaches.

Atlas of EEG, Seizure Semiology, & Management, Second Edition, is a richly-illustrated guide to the performance and interpretation of EEG and management of epilepsy. Revised and updated in its Second Edition, this new text features hundreds of detailed EEGs, and covers the science in extensive scope and detail, beginning with basic electronics and physiology and then moving through EEG interpretation, epilepsy diagnosis, and ultimately epilepsy management. The new edition also includes all basic classifications and definitions of seizures and epilepsy, making it the perfect clinical companion.
Atlas of EEG, Seizure Semiology, & Management utilizes full-color EEG presentations, alongside an easy-to-read synthesis of anatomy, physiology, and available treatment modalities. These detailed explanations of wave pattern, presentation, and treatment provide the student and practitioner with the most informed sense of clinical application and readiness. Atlas of EEG, Seizure Semiology, & Management covers every type of seizure, both epileptic and non-epileptic and divided into eight concise chapters. This unique atlas is necessary reading for all practicing neurologists, fellows, and residents.

The philosopher Henry Richardson's short book is a defense of a position on a neglected topic in medical research ethics. Clinical research ethics has been a longstanding area of study, dating back to the aftermath of the Nazi death-camp doctors and the Tuskegee syphilis study. Most ethical regulations and institutions (such as Institutional Review Boards) have developed in response to those past abuses, including the stress on obtaining informed consent from the subject. Richardson points out that that these ethical regulations do not address one of the key dilemmas faced by medical researchers - whether or not they have obligations towards subjects who need care not directly related to the purpose of the study, termed 'ancillary care obligations'. Does a researcher testing an HIV vaccine in Africa have an obligation to provide anti-retrovirals to those who become HIV positive during the trial? Should a researcher studying a volunteer's brain scan, who sees a possible tumor, do more than simply refer him or her to a specialist? While most would agree that some special obligation does exist in these cases, what is the basis of this obligation, and what are its limits? Richardson's analysis of those key questions and the development of his own position are at the heart of this book, which will appeal to bioethicists studying research ethics, to policy makers, and to political and moral philosophers interested in the obligations of beneficence, one of the key issues in moral theory.

A comprehensive text that looks at respiratory disorders in general, but concentrates on those that are more prevalent in tropical regions. The text is extremely well-illustrated and provides a comprehensive view of different respiratory diseases. A highlight of the book is the discussion on the threat of pulmonary tuberculosis and its unsolved challenges. The epidemiology, the subtle variation in clinical presentation, and the natural history of respiratory diseases in regional contexts have been clearly emphasized. This second edition has been thoroughly revised and updated. Prevailing concepts in lung cancer, asthma, interstitial lung disease, and several other diseases have been discussed at length. The section on newer diagnostic aids involving genetic and molecular biology, has been extensively revised. Every chapter of every section is illustrated wherever necessary with high-quality images contributing to a better understanding of the text.

Insects are the most ecologically important multicellular heterotrophs in terrestrial systems. They play critical roles in ecological food webs, remain devastating agricultural and medical pests, and represent the most diverse group of eukaryotes in terms of species numbers. Their dominant role among terrestrial heterotrophs arises from a number of key physiological traits, and in particular by the developmental and evolutionary plasticity of these traits. Ecological and Environmental Physiology of Insects presents a current and comprehensive overview of how the key physiological traits of insects respond to environmental variation. It forges conceptual links from molecular biology through organismal function to population and community ecology. As with other books in the Series, the emphasis is on the unique physiological characteristics of the insects, but with applications to questions of broad relevance in physiological ecology. As an aid to new researchers on insects, it also includes introductory chapters on the basics and techniques of insect physiology ecology.

This book provides everything nurses need to know about undertaking research and the use of statistics within that research. Original contents: the author used his own content practiced and experienced in his metaphorical career. Research examples box: each chapter includes box of realistic examples to sharpen the reader's critical thinking and understanding. Illuminating statistics: statistics chapter includes illustrative figures and examples for commonly used statistics for ready reference to nursing students. Multiple choice questions: each chapter is offered multiple choice questions helpful in preparation in different nursing examinations. Research misconduct: the only research book in nursing highlighted research and publication misconduct to sensitize the readers for publishing research paper. Aids to student learning: a detailed glossary and comprehensive index are provided for accessing information quickly.

Remarkable advances have occurred since the Series 3 Fascicle published in 1995 with paradigm shifts in every dimension of our understanding of lung tumors including clinical, radiologic, histopathologic, cytopathologic, immunohistochemical, molecular and therapeutic aspects. The molecular revolution leading to effective targeted therapies and breakthroughs in immunotherapy for lung cancer have led to novel approaches incorporating the concept of personalized medicine for patients who historically had little hope. These advances have strengthened the place of pathologists to play a central role in the multidisciplinary team that is now needed to properly diagnose and manage lung cancer patients.

A drug is typically manufactured through chemical synthesis, which means that it is made by combining specific chemical ingredients in an ordered process. Biologics are medicines made from living cells through highly complex manufacturing processes and must be handled and administered under carefully monitored conditions. Biologics are used to prevent, treat, diagnose, or cure a variety of diseases including cancer, chronic kidney disease, autoimmune disorders, and infectious diseases. A biosimilar is a biologic that is similar to another biologic drug already that has already been approved. This book is a complete guide to the use of biologics and biosimilars in the treatment of dermatologic disorders. Beginning with an overview of the history and classification of biologics and the concept of biosimilars, the following chapters explain their therapeutic use for different skin conditions. The final sections cover related topics such as cost effectiveness and quality of life with biologic therapy, and the book concludes with discussion on future developments and the use of small molecule treatment. Key points Complete guide to use of biologics and biosimilars in treatment of dermatologic disorders Covers many different skin diseases and conditions Discusses related topics such as cost effectiveness and quality of life Covers future development of small molecule therapy

This book provides the reader with a thorough understanding of drama therapy methods through the provision of examples so therapists can select the most appropriate methods and apply them themselves. The authors provide a common language for communicating what drama therapists do in terms of diagnoses and interventions, especially for new students in the field. There has been no systematic method developed for drama therapists and drama therapy students for selecting the most appropriate drama therapy technique or method for clients. Typically, students leave university and have to work out how to plan treatment through trial and error. This book is not intended as an instruction manual, but the authors of this book have identified and analysed how they approached this task themselves, and they explain how the theory learnt at university can be put into practice. Their desire is to give early career drama therapy professionals a reliable and effective tool for making the best clinical decisions they can. This book is not only an educational tool, but also a practitioner's reference tool for planning how to address the socio-emotional needs of their clients. Readers will find this timely book offers structure to drama therapy teachers and students alike. It explains the basic tools that drama therapists use in all therapy situations, starting with the therapeutic process, then moves on to identify the core healing concepts that make drama therapy so powerful and unique. The diagnostic systems used by all mental health professionals (DSM-5 and ICD-11) are integrated by relating the core healing concepts and tools to the symptoms of diagnoses. The basic treatment planning process is also discussed. The book then explains how these components are used together systematically through a series of questions (that the therapist asks themself) in order to identify the most appropriate type of intervention for the client. Finally, the book offers several examples of how this system can be applied to a variety of common diagnoses. The appendices provide resources about drama therapy in terms of theory, approach and specific population. Of primary relevance to teachers and students of drama therapy, and drama therapists and integrative arts therapists in training and early career stages. May be useful for other professionals interested in drama therapy and related creative or therapeutic practices where theatre and drama are used. Note: in the US context there is a wider range of related practices, which are often regarded as part of drama therapy.

Evidence-based practice has become the benchmark for quality in healthcare and builds on rules of evidence that have been developed in psychology and other health-care disciplines over many decades. This volume aims to provide clinical neuropsychologists with a practical and approachable reference for skills in evidence-based practice to improve the scientific status of patient care. The core skills involve techniques in critical appraisal of published diagnostic-validity or treatment studies. Critical appraisal skills assist any clinician to evaluate the scientific status of any published study, to identify the patient-relevance of studies with good scientific status, and to calculate individual patient-probability estimates of diagnosis or treatment outcome to guide practice. Initial chapters in this volume review fundamental concepts of construct validity relevant to the assessment of psychopathology and cognitive abilities in neuropsychological populations. These chapters also summarize exciting contemporary development in the theories of personality and psychopathology, and cognitive ability, showing a convergence of theoretical and clinical research to guide clinical practice. Conceptual skills in interpreting construct validity of neuropsychological tests are described in detail in this volume. In addition, a non-mathematical description of the concepts of test score reliability and the neglected topic of interval estimation for individual assessment is provided. As an extension of the concepts of reliability, reliable change indexes are reviewed and the implication of impact on evidence-based practice of test scores reliability and reliable change are described to guide clinicians in their interpretation of test results on single or repeated assessments. Written by some of the foremost experts in the field of clinical neuropsychology and with practical and concrete examples throughout, this volume shows how evidence-based practice is enhanced by reference to good theory, strong construct validity, and better test score reliability.

1. Basic Principles and Cutaneous Signs and Symptoms 2. Pruritus and Dysesthesia 3. Psoriasis and Related Disorders 4. Dermatitis (Eczema) 5. Psychoneurodermatitis 6. Urticaria and Angioedema 7. Erythema Multiforme, Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis, and Fixed Drug Eruption 8. Environmental and Occupational-related Dermatoses 9. Endocrine, Metabolic, and Nutritional Diseases 10. Genetic Diseases of Skin (Genodermatosis) 11. Cutaneous Signs of Systemic Disease 12. Cutaneous Manifestation of Bacterial, Viral, Protozoal, Worm, Fungal Infection, and Others Infection/Infestation 13. Bullous Diseases (Genetic and Acquired) 14. Rheumatologic Dermatology 15. Neutrophilic Dermatosis 16. Disorders of Sebaceous, Eccrine, and Apocrine Glands Index

This fully revised and updated 13th edition covers the entire subjects of obstetrics with a simple, holistic approach to cater to the needs of students.

This 13th edition covers the entire field of gyneecology with a simple holistic approach to cater to the needs of students. After a high-yield synopsis of topics in each chapter, there are detailed explanations of the MCQs from AIIMS (2000-2019), All India (2000-2019) and PGI (2000-2019). Keeping in mind the recent trend, new AIIMS Pattern Questions, NEET Pattern Questions, Image-based questions and color plates of instruments, specimens and radiology are included to enhance the utility of the book. This 13th edition includes annexures for last minute revision. A brief description of instruments is added along with the photograph to help not only the postgraduate aspirants but also the undergraduate students during their viva voce.

In this book, the authors have placed culture in the forefront of their approach to study pain in an integrative manner. Culture should not be considered solely for knowing more about patients' values, beliefs, and practices. It should be studied with the purpose of unveiling its effects upon biological systems and the pain neuromatrix. The book discusses how a multidisciplinary and integrative approach to pain and analgesia should be considered. Some familiarity with the cultural background of patients and awareness of the provider's own cultural characteristics will allow the pain practitioner to better understand patients' values, attitudes and preferences. Knowledge of patients' cultural practices will allow determining the impact of culture on biological processes, including the origin and development of pain-related disease, and the patients' response to pharmacological and non-pharmacological treatments. Acknowledging the interactions of molecules, genes and culture could yield a more appropriate and effective personalized pain medicine. Furthermore, this approach has the potential to transform the way pain medicine is taught to young students and future pain professionals, and in so doing meet the need of trained clinicians who are versed in multiple disciplines and are able to use an integrative approach to diagnose and treat pain. A personalized medicine will have non-negligible positive effects in improving doctor patient relationships, patient satisfaction, adherence to treatment plans, and health outcomes and inequities. It is hoped that the material in this volume will appeal to a broad cross-section of health practitioners, students and academicians, including pain medicine specialists, psychiatrists, psychologists, social workers, mental health, community and public health workers, health policy makers, and health administrators.

Primary immunodeficiency diseases, first recognized 60 years ago, are inherited disorders that affect human adaptive and innate immunity. In most cases, affected individuals experience recurrent infections, but they may also suffer from autoimmune diseases and malignancies. This third edition of Primary Immunodeficiency Diseases provides readers with the historic and scientific background, clinical presentations, immunologic characteristics, and the molecular/genetic underpinnings of this rapidly enlarging class of diseases. With up-to-date diagnostic tools and therapeutic options - from prophylactic anti-infective measures to hematopoietic stem cell transplantation and gene therapy - this volume will remain an authoritative resource on this increasingly important area.

"Progress in Medicinal Chemistry" provides a review of eclectic developments in medicinal chemistry. This volume continues in the serial's tradition of providing an insight into the skills required of the modern medicinal chemist; in particular, the use of an appropriate selection of the wide range of tools now available to solve key scientific problems, including g-secretase modulators, P2X7 antagonists as therapeutic agents for CNS disorders, N-type calcium channel modulators for the treatment of pain, and more.

Extended timely reviews of topics in medicinal chemistryTargets and technologies relevant to the discovery of tomorrow s drugs.Analyses of successful drug discovery programmes"

Physical Activity in Public Health Practice provides the first evidence-based, practical textbook to guide readers through the process of conceptualizing, justifying, implementing, and evaluating physical activity interventions across a broad array of settings and populations. Section One begins with an overview of epidemiology, measurement, critical milestones, and the importance of moving beyond individual-level physical activity intervention, to interventions aimed at policy-, systems-, and environmental-level changes. Section Two considers planning interventions across a variety of settings and populations, including general concepts for implementation and evaluation, how to build effective coalitions, steps for developing community-, regional- or state-level strategic plans, and effectively translating policy into practice. Section Three addresses how to implement physical activity strategies across a variety of settings, including worksites, faith-based settings, healthcare settings, schools, and parks and recreation. This section also provides guidance on the complexities and challenges of targeting interventions for specific populations, such as families, older adults, persons with disabilities, as well as different strategies for urban and rural populations. Lastly, Section Four outlines effective strategies for how to evaluate interventions depending upon impact, outcome, and cost evaluation, and dissemination models for your intervention. Presented from both a research and a practice perspective while discussing the best available research, this book provides the basis for planning and implementing physical activity programs that work and can build healthier communities. This hands-on text incorporates learning objectives, real-world examples, case studies, and bulleted lists whenever possible so that the content can be digested easily not only in undergraduate and graduate course settings but also by public health workers and other health educators in practice. Written by world experts and augmented by practical applications, this textbook prepares public health students and practitioners to develop effective interventions and spur greater physical activity in their communities. Key Features: Provides effective strategies for properly measuring and increasing physical activity in communities Demonstrates how to carry out physical activity interventions across a variety of settings, including schools, communities, worksites and many more Discusses methods for directing physical activity interventions to specific populations Delivers strategies for building successful partnerships and coalitions Practical group activities, exercises, discussion questions, audio podcast discussions, and a full instructor packet accompany the textbook Includes access to fully searchable downloadable eBook

Medical imaging now plays a major role in diagnosis, choice of therapy, and follow-up. However, patients are often intimidated by the multiple imaging modalities available, the indications for their use, the imposing equipment, what the examinations are like and how long they last, and the advantages and disadvantages of various procedures. This book is designed to provide explanations for these and other issues in order to relieve some of the anxiety related to medical imaging studies.