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Books > Science & Mathematics > Biology, life sciences > Molecular biology

Tomorrow's Healthcare by Nano-sized Approaches - A Bold Future for Medicine (Hardcover): Paula Messina, Benedini Luciano,... Tomorrow's Healthcare by Nano-sized Approaches - A Bold Future for Medicine (Hardcover)
Paula Messina, Benedini Luciano, Damian Placente
R4,806 Discovery Miles 48 060 Ships in 12 - 17 working days

Nanomedicine, a scientific branch of nanotechnology that operates on the same scale as biology, offers the possibility of influencing the healing process from inside of the body by manipulating the matter at cellular or molecular levels. Throughout this book, current healing approaches based on this revolutionary new technology are summarized from a scientific assessment. The aim of the authors is to give, through select examples, a deep insight to nanotechnology status and the great progress that its rigorous application will bring to human health. The authors' commitment is to broaden the vision of health professionals who will eventually be the future users of this knowledge.

Analytical Pyrolysis Handbook - Third Edition (Hardcover, 3rd edition): Karen D. Sam, Thomas P Wampler Analytical Pyrolysis Handbook - Third Edition (Hardcover, 3rd edition)
Karen D. Sam, Thomas P Wampler
R4,664 Discovery Miles 46 640 Ships in 12 - 17 working days

Analytical pyrolysis allows scientists to use routine laboratory instrumentation for analyzing complex, opaque, or insoluble samples more effectively than other analytical techniques alone. Analytical Pyrolysis Handbook, Third Edition is a practical guide to the application of pyrolysis techniques to various samples and sample types for a diversity of fields including microbiology, forensic science, industrial research, and environmental analysis. The much-anticipated third edition incorporates recent technological advances that increase the technique's sensitivity to trace elements, improve its reproducibility, and expand its applicability. The book reviews the types of instrumentation available to perform pyrolysis and offers guidance for interfacing instruments and integrating other analytical techniques, including gas chromatography and mass spectrometry. Fully updated with new sample pyrograms, figures, references, and real-world examples, this edition also highlights new areas of application including cultural materials, forensic analysis, and environmental studies. This book illustrates how the latest advances make pyrolysis a practical, cost-effective, reliable, and flexible alternative for increasingly complex sample analyses. Analytical Pyrolysis Handbook, Third Edition is an essential, one-stop guide for determining if pyrolysis meets application-specific needs as well as performing pyrolysis and handling the data obtained.

Microbiomes of Extreme Environments - Biodiversity and Biotechnological Applications (Hardcover): Ajar Nath Yadav, Ali Asghar... Microbiomes of Extreme Environments - Biodiversity and Biotechnological Applications (Hardcover)
Ajar Nath Yadav, Ali Asghar Rastegari, Neelam Yadav
R5,247 Discovery Miles 52 470 Ships in 12 - 17 working days

The extreme microbiomes are those microorganisms thriving under extreme conditions where no other living being will have any chance to survive. The extreme habitats are those presenting high temperatures (thermophiles), low temperature (psychrophiles), hypersaline environments (halophiles), low and high pH (Acidophiles/alkaliphiles), high pressure (Piezophiles) are distributed worldwide. The extreme habitats have proved to offer a unique reservoir of genetic diversity and biological source of extremophiles. The extremophilic microbial diversity and their biotechnological potential use in agricultural and industrial applications will be a milestone for future needs. Extremophiles and their cell components, therefore, are expected to play an important role in the chemical, food, pharmaceutical, paper and textile industries as well as environmental biotechnology.

Trends in Quorum Sensing and Quorum Quenching - New Perspectives and Applications (Hardcover): V Ravishankar Rai, Jamuna A Bai Trends in Quorum Sensing and Quorum Quenching - New Perspectives and Applications (Hardcover)
V Ravishankar Rai, Jamuna A Bai
R5,409 Discovery Miles 54 090 Ships in 12 - 17 working days

The book on Trends in Quorum Sensing and Quorum Quenching: New Perspectives and Applications focuses on the recent advances in the field of quorum sensing in bacteria and the novel strategies developed for quorum sensing inhibition. The topics covered are multidisciplinary and wide-ranging,and includes quorum sensing phenomenon in pathogenic bacteria, food spoilers, and agriculturally relevant bacteria. The applications of quorum sensing inhibitors such as small molecules, bioactives, natural compounds, and quorum quenching enzymes in controlling bacterial infections in clinical settings, agriculture and aquaculture are discussed. The potential use of quorum quenching enzymes for mitigating biofouling is also covered. Special focus is given to exploring quorum sensing inhibitors from microbes and flora inhabiting biodiversity rich regions including tropical rain forests and marine environments. Key features: Covers the fundamental aspects, the progress and challenges in the field of quorum sensing and quorum quenching Reviews quorum sensing in Gram-positive and Gram-negative bacteria of clinical, agricultural, and industrial relevance Discusses the application and future trends of quorum sensing inhibitors from lab to clinical and environmental settings Provides comprehensive coverage on molecular mechanisms in bacterial signaling

Handbook of Tumor Syndromes (Hardcover): Dongyou Liu Handbook of Tumor Syndromes (Hardcover)
Dongyou Liu
R8,793 Discovery Miles 87 930 Ships in 12 - 17 working days

Tumors/cancers are characterized by uncontrolled growths of abnormal cells that extend beyond their usual boundaries and disrupt the normal functions of affected organs and systems. While about 75%-80% of tumors/cancers arise sporadically without a family connection, 20%-25% appear to be familial (including 10%-15% nonhereditary familial tumors [or familial tumors] and 5%-10% hereditary familial tumors [or hereditary tumors]). As nonhereditary and hereditary familial tumors often show both tumor-related and non-tumor-related (or syndromic) symptoms, they are referred to as tumor syndromes (or cancer susceptibility syndromes). In comparison with sporadic tumors/cancers, tumor syndromes (>300 described so far) tend to occur at a younger age, involve multiple organs and systems, produce multiple (often in a distinct spectrum) and bilateral lesions, form multiple hamartomatous, benign, or precursor lesions; locate in specific site(s), display unique syndromic features, and affect multiple members/generations of a family. This book provides state-of-art and authoritative coverage of nearly 100 tumor syndromes, with chapters presenting overviews of individual tumor syndromes in relation to their biology, epidemiology, pathogenesis, clinical features, diagnosis, treatment, and prognosis. Featuring contributions from oncologists, clinicians, and specialists, the book offers a reliable, comprehensive reference on tumor syndromes for scholars and students of medicine, dentistry, pharmacology, nursing, public health, and other biomedical disciplines. Key Features Reviews the biology, epidemiology, pathogenesis, and clinical features of tumor syndromes Contains up-to-date information on the diagnosis and treatment of tumor syndromes Includes expert coverage from leading oncologists and clinicians Related Titles J. R. McIntosh, Understanding Cancer: An Introduction to the Biology, Medicine, and Societal Implications of This Disease (ISBN 978-0-8153-4535-0) P. S. T. Shanmugam, Understanding Cancer Therapies (ISBN 978-1-1381-9815-9) J. M. Baehring and J. M. Piepmeier, eds., Brain Tumors: Practical Guide to Diagnosis and Treatment (ISBN 978-0-3673-9022-8) D. Liu, Tumors and Cancers: Endocrine Glands - Blood - Marrow - Lymph (ISBN 978-1-4987-2975-8) Dongyou Liu, PhD, has worked at several research and clinical laboratories in Australia and the United States for the past three decades, with a focus on molecular characterization of microbial pathogens and detection of human genetic disorders and tumors/cancers. He is the primary author of more than 50 original research and review articles in various peer-reviewed international journals, the contributor of 197 book chapters, and the editor of more than 10 books.

New Technologies for Reclamation of Industrial Wastewater (Hardcover): Pankaj Chowdhary, Sujata Mani New Technologies for Reclamation of Industrial Wastewater (Hardcover)
Pankaj Chowdhary, Sujata Mani
R1,633 Discovery Miles 16 330 Ships in 12 - 17 working days

New Technologies for Reclamation of Industrial Wastewater provides information on several types of industrial wastewaters containing a variety of toxic and recalcitrant compounds. It also focuses on the ecotoxicological and health hazards posed by the chemicals released along with industrial effluents. It covers various conventional as well as modern wastewater-treatment technologies and their advantages and disadvantages. Features: Elucidates various types of industrial wastewaters generated, their fate and consequences Describes the ecotoxicological and health implications of industrial contaminants Provides details on conventional treatment technologies along with modern and emerging wastewater-treatment methods Discusses the merits and demerits of both conventional and emerging treatment technologies

Extremophiles - From Biology to Biotechnology (Paperback): Ravi V. Durvasula, D.V. Subba Rao Extremophiles - From Biology to Biotechnology (Paperback)
Ravi V. Durvasula, D.V. Subba Rao
R1,532 Discovery Miles 15 320 Ships in 12 - 17 working days

Highly recommended by CHOICE, Oct 2018 Extremophiles are nature's ultimate survivors, thriving in environments ranging from the frozen Antarctic to abyssal hot hydrothermal vents. Their lifeforms span bacteria to fishes, and are categorized as halophiles from hypersaline environments, acidophiles from acidic waters, psychrophiles from cold habitats, and thermophiles from warm waters. Extremophiles: From Biology to Biotechnology comprehensively covers the basic biology, physiology, habitats, secondary metabolites for bioprospecting, and biotechnology of these extreme survivors. The chapters focus on the novel genetic and biochemical traits that lend these organisms to biotechnological applications. Couples studies of marine extremophile biology/genomics and extremophile culture for biotechnological applications with the latest advances in bio-prospecting and bio-product development Includes practical experiments that a laboratory can use to replicate extreme habitats for research purposes Presents latest advances in extremophile genomics to give the reader a better understanding of the regulatory mechanisms of extremophiles Offers insights into the production of commercially important extremozymes, carotenoids, bioactive compounds and secondary metabolites of medicinal value. This unique guide serves as a resource for biotechnologists who wish to explore extremophiles for their commercial potential, as well as a valuable reference for teaching undergraduate, graduate and postgraduate students.

Energy, Information, Feedback, Adaptation, and Self-organization - The Fundamental Elements of Life and Society (Hardcover, 1st... Energy, Information, Feedback, Adaptation, and Self-organization - The Fundamental Elements of Life and Society (Hardcover, 1st ed. 2018)
Spyros G. Tzafestas
R5,838 Discovery Miles 58 380 Ships in 10 - 15 working days

This unique book offers a comprehensive and integrated introduction to the five fundamental elements of life and society: energy, information, feedback, adaptation, and self-organization. It is divided into two parts. Part I is concerned with energy (definition, history, energy types, energy sources, environmental impact); thermodynamics (laws, entropy definitions, energy, branches of thermodynamics, entropy interpretations, arrow of time); information (communication and transmission, modulation-demodulation, coding-decoding, information theory, information technology, information science, information systems); feedback control (history, classical methodologies, modern methodologies); adaptation (definition, mechanisms, measurement, complex adaptive systems, complexity, emergence); and self-organization (definitions/opinions, self-organized criticality, cybernetics, self-organization in complex adaptive systems, examples in nature). In turn, Part II studies the roles, impacts, and applications of the five above-mentioned elements in life and society, namely energy (biochemical energy pathways, energy flows through food chains, evolution of energy resources, energy and economy); information (information in biology, biocomputation, information technology in office automation, power generation/distribution, manufacturing, business, transportation), feedback (temperature, water, sugar and hydrogen ion regulation, autocatalysis, biological modeling, control of hard/technological and soft/managerial systems), adaptation and self-organization (ecosystems, climate change, stock market, knowledge management, man-made self-organized controllers, traffic lights control).

Microbial Endophytes (Paperback): Charles W. Bacon, James White Microbial Endophytes (Paperback)
Charles W. Bacon, James White
R1,767 Discovery Miles 17 670 Ships in 12 - 17 working days

Examining intercellular infections in certain plant species that lead to a symbiotic relationship between the host and its endophytic microbes, this volume demonstrates the ability of many types of endosymbionts, acting as a unit with hosts to better survive, compete and reproduce. Practical applications of such endophytes are also discussed, for example, pharmaceutical developments and agricultural management.

Sarcocystosis of Animals and Humans (Paperback, 2nd edition): J.P. Dubey, R. Calero-Bernal, B.M. Rosenthal, C. A. Speer, R.... Sarcocystosis of Animals and Humans (Paperback, 2nd edition)
J.P. Dubey, R. Calero-Bernal, B.M. Rosenthal, C. A. Speer, R. Fayer
R1,452 Discovery Miles 14 520 Ships in 12 - 17 working days

Sarcocystis is one of the most prevalent parasites of livestock and also infects many wild mammals, birds, and humans. Written by the authors who pioneered studies of Sarcocystosis of domestic animals, Sarcocystosis of Animals and Humans, Second Edition provides a current and comprehensive review of Sarcocystis and the infections it causes in animals and humans. The book reviews the history, structure, life cycle, pathogenesis, lesions, clinical signs, diagnosis, immunity, epidemiology, treatment, prevention, and control of Sarcocystosis. See What's New in the Second Edition: New section on molecular diagnosis and DNA characterization of Sarcocystis species New section on clinical sarcocystosis outbreaks in humans is added with a summary of all reports, symptoms, diagnosis, and treatment New section on acute fatal outbreaks of sarcocystosis in birds Complete description of the life cycles of all Sarcocystis species List of all species whose life cycles are known Comprehensive information on diagnosis, including molecular diagnosis Additional information on zoonoses In-depth coverage of treatment, control, and prevention Maintaining the format that made the first edition so popular, this new edition covers recent developments and excludes information that has become redundant. The authors include all literature and provide a comprehensive review of biology, clinical disease, economic losses, public health concerns, diagnosis, treatment, and prevention. They have tabulated information on all Sarcocystis species by host and listed species that should be considered species inquirende/invalid.

Estrogen Receptors - Methods and Protocols (Hardcover, 1st ed. 2016): Kathleen M Eyster Estrogen Receptors - Methods and Protocols (Hardcover, 1st ed. 2016)
Kathleen M Eyster
R4,643 Discovery Miles 46 430 Ships in 10 - 15 working days

This volume examines a wide array of vital technologies for advancing our understanding of the receptor-mediated actions of estrogen. The protocols in this book range from standard methods and vital laboratory workhorses, such as receptor binding assays and western blot, to newer technologies such as RNAseq and proximity ligation assay. Chapters also discuss protocols from a broad range of tissue types to demonstrate the variety of estrogen receptor effects. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Estrogen Receptors: Methods and Protocols is a detailed and helpful resource for scientists who are intrigued by the many facets of estrogen. The chapter 'Bioinformatics Analysis of Estrogen-Responsive Genes' is open access under a CC BY 4.0 license.

Kinase Screening and Profiling - Methods and Protocols (Hardcover, 1st ed. 2016): Hicham Zegzouti, Said A Goueli Kinase Screening and Profiling - Methods and Protocols (Hardcover, 1st ed. 2016)
Hicham Zegzouti, Said A Goueli
R4,527 R3,778 Discovery Miles 37 780 Save R749 (17%) Ships in 12 - 17 working days

This volume focuses on screening and profiling kinase inhibitors or activators. Chapters in this book cover several facets of the drug discovery processes starting with target identification, and assay development and screening chemical libraries for hit identification and lead optimization. The profiling portion of Kinase Screening and Profiling: Methods and Protocols discusses several strategies and techniques that are required to minimize off target hits and reduce cellular toxicities that are caused by liability kinases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Timely and authoritative, Kinase Screening and Profiling: Methods and Protocols, will benefit scientists and researchers who are interested in exploring the role of kinases in academic, as well as pharmaceutical research.

Statistical Analysis in Proteomics (Hardcover, 1st ed. 2016): Klaus Jung Statistical Analysis in Proteomics (Hardcover, 1st ed. 2016)
Klaus Jung
R4,667 R3,909 Discovery Miles 39 090 Save R758 (16%) Ships in 12 - 17 working days

This valuable collection aims to provide a collection of frequently used statistical methods in the field of proteomics. Although there is a large overlap between statistical methods for the different 'omics' fields, methods for analyzing data from proteomics experiments need their own specific adaptations. To satisfy that need, Statistical Analysis in Proteomics focuses on the planning of proteomics experiments, the preprocessing and analysis of the data, the integration of proteomics data with other high-throughput data, as well as some special topics. Written for the highly successful Methods in Molecular Biology series, the chapters contain the kind of detail and expert implementation advice that makes for a smooth transition to the laboratory. Practical and authoritative, Statistical Analysis in Proteomics serves as an ideal reference for statisticians involved in the planning and analysis of proteomics experiments, beginners as well as advanced researchers, and also for biologists, biochemists, and medical researchers who want to learn more about the statistical opportunities in the analysis of proteomics data.

Oxidants, Antioxidants And Free Radicals (Paperback): Harry Salem, Steven Baskin Oxidants, Antioxidants And Free Radicals (Paperback)
Harry Salem, Steven Baskin
R1,767 Discovery Miles 17 670 Ships in 12 - 17 working days

This volume collates articles investigating antioxidant, oxidant and free radical research. It examines the role of such research in health and disease, particulary with respect to developing greater understanding about the many interactions between oxidants and antioxidants, and how such substances may act as natural protectants and /or natural toxicants.

Post-Transcriptional Gene Regulation (Hardcover, 2nd ed. 2016): Erik Dassi Post-Transcriptional Gene Regulation (Hardcover, 2nd ed. 2016)
Erik Dassi
R5,025 R4,038 Discovery Miles 40 380 Save R987 (20%) Ships in 12 - 17 working days

This volume aims to provide the most recent advances in techniques for studying gene expression regulation at the post-transcriptional level. Post-Transcriptional Gene Regulation, Second Edition is organized in six sections describing bioinformatics approaches for studying post-transcriptional regulation, various expression profiling approaches, protein-RNA interaction and non-coding RNA investigation techniques, methods for profiling RNA modifications, and other techniques such as alternative translation initiation or polyadenylation sites determination. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Post-Transcriptional Gene Regulation, Second Edition is a versatile resource to researchers studying post-transcriptional regulation, introducing the most recent techniques and providing a comprehensive guide to their implementation.

Molecular Detection of Human Parasitic Pathogens (Hardcover, New): Dongyou Liu Molecular Detection of Human Parasitic Pathogens (Hardcover, New)
Dongyou Liu
R6,945 Discovery Miles 69 450 Ships in 12 - 17 working days

Traditionally, laboratory identification of parasites has relied upon various phenotypic procedures that detect their morphological, biological, and immunological features. Because these procedures tend to be time-consuming and technically demanding, molecular methods based on nucleic acid amplification technologies have been increasingly utilized for rapid, sensitive, and specific characterization of parasites.

The large number of original and modified molecular protocols that have been developed over the years creates a dilemma for those attempting to adopt the most appropriate protocol for streamlined identification and detection of human pathogenic organisms of interest. Part of a four-volume collection, Molecular Detection of Human Parasitic Pathogens provides a reliable and comprehensive resource on the molecular detection and identification of major human parasitic pathogens.

This volume contains expert contributions from international scientists involved in human parasitic pathogen research and diagnosis. Following a similar format throughout, each chapter includes:

  • A brief review on the classification, biology, epidemiology, clinical features, and diagnosis of an important pathogenic parasitic genus/group
  • An outline of clinical sample collection and preparation procedures and a selection of representative stepwise molecular protocols
  • A discussion on further research needs relating to improved diagnoses of major human parasitic pathogens

This versatile reference on molecular detection and identification of major human parasitic pathogens is an indispensable tool for upcoming and experienced medical, veterinary, and industrial laboratory scientists engaged in parasite characterization. It is also suitable as a textbook for undergraduate and graduate students majoring in parasitology.

Molecular and Cellular Methods in Developmental Toxicology (Hardcover): George P. Daston Molecular and Cellular Methods in Developmental Toxicology (Hardcover)
George P. Daston
R5,101 R3,488 Discovery Miles 34 880 Save R1,613 (32%) Ships in 12 - 17 working days

This new manual provides a convenient source of experimental procedures, including the most modern and frequently used molecular and cellular techniques. Experimental protocols have been carefully selected by developmental toxicologists for developmental toxicologists. The most important new trends, such as evaluation of the safety of therapeutic antisense oligonucleotides, studies of the role of cell death in abnormal development, and the identification of sparingly expressed developmental control genes are featured. This is the perfect manual for scientists trained in classical developmental toxicology who want to add molecular and cellular methods to their research.

Fungi - Experimental Methods In Biology, Second Edition (Hardcover, 2nd edition): Ramesh Maheshwari Fungi - Experimental Methods In Biology, Second Edition (Hardcover, 2nd edition)
Ramesh Maheshwari
R3,932 Discovery Miles 39 320 Ships in 12 - 17 working days

Fungi are now at the forefront of research on mechanisms in gene silencing, biological rhythm, mating processes, biogenesis of intracellular organelles, adaptations to hostile habitats, structure of natural populations, and speciation. Because of their small genomes, fungi are being used in "systems biology" to understand the connections between genes, proteins, and metabolic and signaling pathways. The ease with which yeasts and fungi can be cultivated in simple nutritive media has also made these eukaryotic organisms the choice material for basic and applied research. Fungi: Experimental Methods in Biology, Second Edition presents the latest information on fungal biology generated through advances in genetics, molecular biology, and biochemistry. It gives an account of real experiments that have been carried out on the diverse lifestyles of these organisms. Following in the footsteps of its highly-praised predecessor, this book continues to be a comprehensive review of the state of our knowledge about how fungi function. Examining both unicellular and multicellular fungi, this accessible book covers: Special features of fungi Interaction of fungi with other organisms Use of fungi as sources of chemicals for human health and welfare Model fungi in research Gene manipulation Adaptations Natural populations Throughout, the book draws attention to unsolved questions and to the opportunities offered by the diversity of fungi. Written by a prominent mycologist, it provides an excellent introduction and reference for beginning researchers as well as for experienced professionals. What's New in This Edition: New chapters on spores' dormancy, germination, and uses; fungi as scavengers; and fungi as chemical factories All chapters substantially revised, updated, and rewritten, in particular The Hyphal Mode of Life, Fungi as Symbiotic Partners, and Fungi as Plant Pathogens New material on the use of yeast for functional analysis of genomes; the use of Neurospora in cytogenetics and genes controlling conidiation; and the identification of the clock gene A new glossary to reinforce important concepts

Nucleic Acid Testing for Human Disease (Paperback): Attila Lorincz Nucleic Acid Testing for Human Disease (Paperback)
Attila Lorincz
R1,803 Discovery Miles 18 030 Ships in 12 - 17 working days

Nucleic Acid Testing for Human Disease describes various techniques including target and signal amplification-based NAT procedures, microarrays, bead-based multiplex assays, in situ hybridization, and SNP techniques. This book discusses RNA expression profiling and laboratory issues such as the need for proper validation of tests intended for routine use. It focuses on specific applications of NATs to human disease diagnosis and treatment, from viral, bacterial, fungal, and protozoan detection to genetic exploration by SNP determinations, patterns of RNA expression, and the growing relevance of epigenetic changes. It also offers different perspectives on future directions in the field.

Integrated Molecular Evolution (Paperback, 2nd edition): Scott Orland Rogers Integrated Molecular Evolution (Paperback, 2nd edition)
Scott Orland Rogers
R1,817 Discovery Miles 18 170 Ships in 12 - 17 working days

Evolutionary biology has increasingly relied upon tools developed in molecular biology that allow for the structure and function of macromolecules to be used as data for exploring the patterns and processes of evolutionary change. Integrated Molecular Evolution, Second Edition is a textbook intended to expansively and comprehensive review evolutionary studies now routinely using molecular data. This new edition has been thoroughly updated and expanded, and provides a basic summary of evolutionary biology as well as a review of current phylogenetics and phylogenomics. Reflecting a burgeoning pedagogical landscape, this new edition includes nearly double the number of chapters, including a new section on molecular and bioinformatic methods. Dedicated chapters were added on: Evolution of the genetic code Mendelian genetics and population genetics Natural selection Horizontal gene transfers Animal development and plant development Cancer Extraction of biological molecules Analytical methods Sequencing methods and sequencing analyses Omics Phylogenetics and phylogenetic networks Protein trafficking Human genomics More than 400 illustrations appear in this edition, doubling the number included in the first edition, and over 100 of these diagrams are now in color. The second edition combines and integrates extensive summaries of genetics and evolutionary biology in a manner that is accessible for students at either the graduate or undergraduate level. It also provides both the basic foundations of molecular evolution, such as the structure and function of DNA, RNA and proteins, as well as more advanced chapters reviewing analytical techniques for obtaining sequences, and interpreting and archiving molecular and genomic data.

Handbook of Detection of Enzymes on Electrophoretic Gels (Paperback, 2nd edition): Gennady P. Manchenko Handbook of Detection of Enzymes on Electrophoretic Gels (Paperback, 2nd edition)
Gennady P. Manchenko
R1,813 Discovery Miles 18 130 Ships in 12 - 17 working days

Still widely used as gene markers, isozymes detected by zymogram techniques have proven valuable in a range of other biological applications over the last few years. Along with these new applications, many new techniques have also emerged. Yet more than eight years since the Handbook of Detection of Enzymes on Electrophoretic Gels was first published, it remains the only book completely devoted to zymogram methods. The time has come to bring its contents up to date. New in the Second Edition: An overview of new applications of enzyme electrophoresis and zymogram techniques Zymogram techniques for approximately 100 enzymes not included in the first edition, bringing the total to more than 900 methods for detecting more than 400 different enzymes Information on subunit structure included within the enzyme sheets to facilitate interpretation of isozyme patterns detected on zymograms An appendix containing information on the buffer systems most commonly used for enzyme electrophoresis in starch, cellulose acetate, and polyacrylamide gels. The second edition of this bestselling handbook makes significant additions to the set of reliable gene markers suitable for electrophoretic analysis. It also strengthens the value of enzyme electrophoresis as a powerful tool proven successful in solving a variety of problems encountered across many biological areas, including the post-genome biology.

Biochemistry and Molecular Biology Compendium (Hardcover, 2nd edition): Roger L. Lundblad Biochemistry and Molecular Biology Compendium (Hardcover, 2nd edition)
Roger L. Lundblad
R5,267 Discovery Miles 52 670 Ships in 12 - 17 working days

This book is an accessible resource offering practical information not found in more database-oriented resources. The first chapter lists acronyms with definitions, and a glossary of terms and subjects used in biochemistry, molecular biology, biotechnology, proteomics, genomics, and systems biology. There follows chapters on chemicals employed in biochemistry and molecular biology, complete with properties and structure drawings. Researchers will find this book to be a valuable tool that will save them time, as well as provide essential links to the roots of their science. Key selling features: Contains an extensive list of commonly used acronyms with definitions Offers a highly readable glossary for systems and techniques Provides comprehensive information for the validation of biotechnology assays and manufacturing processes Includes a list of Log P values, water solubility, and molecular weight for selected chemicals Gives a detailed listing of protease inhibitors and cocktails, as well as a list of buffers

Stem Cells - Biology and Application (Hardcover): Jonathan Frampton, Mary Clarke Stem Cells - Biology and Application (Hardcover)
Jonathan Frampton, Mary Clarke
R4,152 Discovery Miles 41 520 Ships in 12 - 17 working days

Stem cell science, encompassing basic biology to practical application, is both vast and diverse. A full appreciation of it requires an understanding of cell and molecular biology, tissue structure and physiology, the practicalities of tissue engineering and bioprocessing, and the pathways to clinical implementation-including the ethical and regulatory imperatives that our society requires us to address. Expectation and debate have been driven by the allure of regenerative medicine using stem cells as a source of replacements for damaged or aged tissues. The potential of stem cell application goes far beyond this. Highly innovative uses of stem cells are emerging as possible therapies for cancers, treating acute damage in conditions such as stroke and myocardial infarction, and resolving a whole range of diseases. Stem Cells: Biology and Application presents the basic concepts underlying the fast-moving science of stem cell biology. This textbook is written for an advanced stem cell biology course. The target audience includes senior undergraduates, first year graduate students, and practitioners in molecular biology, biology, and biomedical engineering. Stem Cells provides a comprehensive understanding of these unique cells, highlighting key areas of research, associated controversies, case studies, technologies, and pioneers in the field.

Rice Improvement in the Genomics Era (Paperback): Swapan K. Datta Rice Improvement in the Genomics Era (Paperback)
Swapan K. Datta
R1,894 Discovery Miles 18 940 Ships in 12 - 17 working days

Rice is probably the most important food crop in the world, feeding half its population. Rice Improvement in the Genomics Era examines the findings in the current studies of rice improvement, using the modern genomic tools available in today's agriculture to better enable food security and human welfare. This comprehensive text describes in detail the latest tools of genomics and the application of biotechnology to improve this crucial food crop that is the most important staple of developing countries. Top respected experts in rice science and genomics offer the latest in cutting-edge science and research based on genome sequencing, gene technology, and molecular biology. Rice Improvement in the Genomics Era provides a wide range of information essential to any professional concerned with food safety, security, and sustainability. This valuable source comprehensively and accurately describes rice science from the basics of modern genomics on up to the application of biotechnology. This text is extensively referenced, and includes photographs, tables, graphs, and figures to clearly present information. Topics discussed include: * rice genome sequencing project and its impact * gene expression using microarray system * haploid breeding * hybrid rice technology * Bt and disease resistance * abiotic stress tolerance * ensuring rice quality * genetically improved nutrition in rice * human milk proteins in rice grains * food safety of transgenic crops * and much more! Rice Improvement in the Genomics Era is an informative resource for educators, students, rice scientists, rice breeders, plant biotechnologists, researchers, and policymakers in agricultural sciences, rice improvement, and biotechnology. This source is a crucial addition to agricultural institutions, libraries, and teaching organizations.

Modelling Metabolism with Mathematica (Paperback): Peter Mulquiney, Philip W. Kuchel Modelling Metabolism with Mathematica (Paperback)
Peter Mulquiney, Philip W. Kuchel
R1,867 Discovery Miles 18 670 Ships in 12 - 17 working days

With the advent of sophisticated general programming environments like Mathematica, the task of developing new models of metabolism and visualizing their responses has become accessible to students of biochemistry and the life sciences in general. Modelling Metabolism with Mathematica presents the approaches, methods, tools, and algorithms for modelling the chemical-dynamics of metabolic pathways. The authors explain the concepts underpinning the deterministic theory of chemical and enzyme kinetics, present a graded series of computer models of metabolic pathways leading up to that of the human erythrocyte, and document a consistent set of rate equations and associated kinetic parameters. The experimental and theoretical study of metabolism in mammalian cells has a long and fruitful history, but our understanding of cellular metabolism at the molecular level is far from complete. This book enables its readers to formulate their own models of time-dependent metabolic systems and aids them in the quest for the many fundamental and clinically relevant discoveries that remain to be made.

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