This volume provides updated, in-depth material on the application of intelligent optimization in biology and medicine. The aim of the book is to present solutions to the challenges and problems facing biology and medicine applications. This Volume comprises of 13 chapters, including an overview chapter, providing an up-to-date and state-of-the research on the application of intelligent optimization for bioinformatics applications, DNA based Steganography, a modified Particle Swarm Optimization Algorithm for Solving Capacitated Maximal Covering Location Problem in Healthcare Systems, Optimization Methods for Medical Image Super Resolution Reconstruction and breast cancer classification. Moreover, some chapters that describe several bio-inspired approaches in MEDLINE Text Mining, DNA-Binding Proteins and Classes, Optimized Tumor Breast Cancer Classification using Combining Random Subspace and Static Classifiers Selection Paradigms, and Dental Image Registration. The book will be a useful compendium for a broad range of readers-from students of undergraduate to postgraduate levels and also for researchers, professionals, etc.-who wish to enrich their knowledge on Intelligent Optimization in Biology and Medicine and applications with one single book.

This book collects chapters on contemporary topics on metric fixed point theory and its applications in science, engineering, fractals, and behavioral sciences. Chapters contributed by renowned researchers from across the world, this book includes several useful tools and techniques for the development of skills and expertise in the area. The book presents the study of common fixed points in a generalized metric space and fixed point results with applications in various modular metric spaces. New insight into parametric metric spaces as well as study of variational inequalities and variational control problems have been included.

This book covers a large spectrum of cutting-edge game theory applications in management science in which Professor Georges Zaccour has made significant contributions. The book consists of 21 chapters and highlights the latest treatments of game theory in various areas, including marketing, supply chains, energy and environmental management, and cyber defense. With this book, former Ph.D. students and successful research collaborators of Professor Zaccour wish to honor his many scientific achievements.

The aim of Metaheuristics: Progress in Complex Systems Optimization is to provide several different kinds of information: a delineation of general metaheuristics methods, a number of state-of-the-art articles from a variety of well-known classical application areas as well as an outlook to modern computational methods in promising new areas. Therefore, this book may equally serve as a textbook in graduate courses for students, as a reference book for people interested in engineering or social sciences, and as a collection of new and promising avenues for researchers working in this field. Highlighted are recent developments in the areas of Simulated Annealing, Path Relinking, Scatter Search, Tabu Search, Variable Neighborhood Search, Hyper-heuristics, Constraint Programming, Iterated Local Search, GRASP, bio-inspired algorithms like Genetic Algorithms, Memetic Algorithms, Ant Colony Optimization or Swarm Intelligence, and several other paradigms.

In the fifties and sixties, several real problems, old and new, especially in Physics, Mechanics, Fluidodynamics, Structural Engi- neering, have shown the need of new mathematical models for study- ing the equilibrium of a system. This has led to the formulation of Variational Inequalities (by G. Stampacchia), and to the develop- ment of Complementarity Systems (by W.S. Dorn, G.B. Dantzig, R.W. Cottle, O.L. Mangasarian et al.) with important applications in the elasto-plastic field (initiated by G. Maier). The great advan- tage of these models is that the equilibrium is not necessarily the extremum of functional, like energy, so that no such functional must be supposed to exist. In the same decades, in some fields like Control Theory, Net- works, Industrial Systems, Logistics, Management Science, there has been a strong request of mathmatical models for optimizing situa- tions where there are concurrent objectives, so that Vector Optimiza- tion (initiated by W. Pareto) has received new impetus. With regard to equilibrium problems, Vector Optimization has the above - mentioned drawback of being obliged to assume the exis- tence of a (vector) functional. Therefore, at the end of the seventies the study of Vector Variational Inequalities began with the scope of exploiting the advantages of both variational and vector models. This volume puts together most of the recent mathematical results in Vector Variational Inequalities with the purpose of contributing to further research.

This book presents new optimization algorithms designed to improve the efficiency of tool paths for five-axis NC machining of sculptured surfaces. The book covers both the structure of the SLAM problem in general and proposes a new extremely efficient approach. It can be used by undergraduate and graduate students and researchers in the field of NC machining and CAD/CAM as well as by corporate research groups for advanced optimization of cutting operations.

This book is an authoritative collection of contributions in the field of soft-computing. Based on selected works presented at the 6th World Conference on Soft Computing, held on May 22-25, 2016, in Berkeley, USA, it describes new theoretical advances, as well as cutting-edge methods and applications. Theories cover a wealth of topics, such as fuzzy logic, cognitive modeling, Bayesian and probabilistic methods, multi-criteria decision making, utility theory, approximate reasoning, human-centric computing and many others. Applications concerns a number of fields, such as internet and semantic web, social networks and trust, control and robotics, computer vision, medicine and bioinformatics, as well as finance, security and e-Commerce, among others. Dedicated to the 50th Anniversary of Fuzzy Logic and to the 95th Birthday Anniversary of Lotfi A. Zadeh, the book not only offers a timely view on the field, yet it also discusses thought-provoking developments and challenges, thus fostering new research directions in the diverse areas of soft computing.

In the field of nondifferentiable nonconvex optimization, one of the most intensely investigated areas is that of optimization problems involving multivalued mappings in constraints or as the objective function. This book focuses on the tremendous development in the field that has taken place since the publication of the most recent volumes on the subject. The new topics studied include the formulation of optimality conditions using different kinds of generalized derivatives for set-valued mappings (such as, for example, the coderivative of Mordukhovich), the opening of new applications (e.g., the calibration of water supply systems), or the elaboration of new solution algorithms (e.g., smoothing methods). The book is divided into three parts. The focus in the first part is on bilevel programming. The chapters in the second part contain investigations of mathematical programs with equilibrium constraints. The third part is on multivalued set-valued optimization. The chapters were written by outstanding experts in the areas of bilevel programming, mathematical programs with equilibrium (or complementarity) constraints (MPEC), and set-valued optimization problems.

This book presents essential concepts of traditional Flower Pollination Algorithm (FPA) and its recent variants and also its application to find optimal solution for a variety of real-world engineering and medical problems. Swarm intelligence-based meta-heuristic algorithms are extensively implemented to solve a variety of real-world optimization problems due to its adaptability and robustness. FPA is one of the most successful swarm intelligence procedures developed in 2012 and extensively used in various optimization tasks for more than a decade. The mathematical model of FPA is quite straightforward and easy to understand and enhance, compared to other swarm approaches. Hence, FPA has attracted attention of researchers, who are working to find the optimal solutions in variety of domains, such as N-dimensional numerical optimization, constrained/unconstrained optimization, and linear/nonlinear optimization problems. Along with the traditional bat algorithm, the enhanced versions of FPA are also considered to solve a variety of optimization problems in science, engineering, and medical applications.

This book describes applications of Jaya and Rao algorithms on real case studies concerning different renewable energy sources. In the last few decades, researchers have focused on renewable energy resources like solar energy, bio-energy, wave energy, ocean thermal energy, tidal energy, geothermal energy, and wind energy. This has resulted in the development of new techniques and tools that could harvest energy from renewable energy sources. Many researchers and scientists have focused on developing and optimizing the energy systems to extract and utilize renewable energy more efficiently. In this book, recently developed Jaya and Rao (Rao-1, Rao-2, and Rao-3) algorithms are introduced for single- and multi-objective optimization of selected renewable energy systems. The results of applications of the different versions of Jaya and Rao algorithms are compared with the other optimization techniques like GA, NSGA-II, PSO, MOPSO, ABC, etc., and the performance of the Jaya and Rao algorithms is highlighted compared to other optimization algorithms in the case of renewable energy systems. The book also includes the validation of different versions of the Jaya and Rao algorithms through the application to complex single- and multi-objective unconstrained benchmark functions. The algorithms and computer codes of different version of Jaya and Rao algorithms are included in the book that will be very much useful to readers in industry and academic research.

Structural optimization is currently attracting considerable attention. Interest in - search in optimal design has grown in connection with the rapid development of aeronautical and space technologies, shipbuilding, and design of precision mach- ery. A special ?eld in these investigations is devoted to structural optimization with incomplete information (incomplete data). The importance of these investigations is explained as follows. The conventional theory of optimal structural design - sumes precise knowledge of material parameters, including damage characteristics and loadings applied to the structure. In practice such precise knowledge is seldom available. Thus, it is important to be able to predict the sensitivity of a designed structure to random ?uctuations in the environment and to variations in the material properties. To design reliable structures it is necessary to apply the so-called gu- anteed approach, based on a "worst case scenario" or a more optimistic probabilistic approach, if we have additional statistical data. Problems of optimal design with incomplete information also have consid- able theoretical importance. The introduction and investigations into new types of mathematical problems are interesting in themselves. Note that some ga- theoretical optimization problems arise for which there are no systematic techniques of investigation. This monograph is devoted to the exposition of new ways of formulating and solving problems of structural optimization with incomplete information. We recall some research results concerning the optimum shape and structural properties of bodies subjected to external loadings.

The theory of probability began in the seventeenth century with attempts to calculate the odds of winning in certain games of chance. However, it was not until the middle of the twentieth century that mathematicians de veloped general techniques for maximizing the chances of beating a casino or winning against an intelligent opponent. These methods of finding op timal strategies for a player are at the heart of the modern theories of stochastic control and stochastic games. There are numerous applications to engineering and the social sciences, but the liveliest intuition still comes from gambling. The now classic work How to Gamble If You Must: Inequalities for Stochastic Processes by Dubins and Savage (1965) uses gambling termi nology and examples to develop an elegant, deep, and quite general theory of discrete-time stochastic control. A gambler "controls" the stochastic pro cess of his or her successive fortunes by choosing which games to play and what bets to make."

The rich, multi-faceted and multi-disciplinary field of matching-based market design is an active and important one due to its highly successful applications with economic and sociological impact. Its home is economics, but with intimate connections to algorithm design and operations research. With chapters contributed by over fifty top researchers from all three disciplines, this volume is unique in its breadth and depth, while still being a cohesive and unified picture of the field, suitable for the uninitiated as well as the expert. It explains the dominant ideas from computer science and economics underlying the most important results on market design and introduces the main algorithmic questions and combinatorial structures. Methodologies and applications from both the pre-Internet and post-Internet eras are covered in detail. Key chapters discuss the basic notions of efficiency, fairness and incentives, and the way market design seeks solutions guided by normative criteria borrowed from social choice theory.

This book presents the state-of-the-art methods in Linear Integer Programming, including some new algorithms and heuristic methods developed by the authors in recent years. Topics as Characteristic equation (CE), application of CE to bi-objective and multi-objective problems, Binary integer problems, Mixed-integer models, Knapsack models, Complexity reduction, Feasible-space reduction, Random search, Connected graph are also treated.

This book defines and studies a combinatorial object called the pedigree and develops the theory for optimising a linear function over the convex hull of pedigrees (the Pedigree polytope). A strongly polynomial algorithm implementing the framework given in the book for checking membership in the pedigree polytope is a major contribution. This book challenges the popularly held belief in computer science that a problem included in the NP-complete class may not have a polynomial algorithm to solve. By showing STSP has a polynomial algorithm, this book settles the P vs NP question. This book has illustrative examples, figures, and easily accessible proofs for showing this unexpected result. This book introduces novel constructions and ideas previously not used in the literature. Another interesting feature of this book is it uses basic max-flow and linear multicommodity flow algorithms and concepts in these proofs establishing efficient membership checking for the pedigree polytope. Chapters 3-7 can be adopted to give a course on Efficient Combinatorial Optimization. This book is the culmination of the author's research that started in 1982 through a presentation on a new formulation of STSP at the XIth International Symposium on Mathematical Programming at Bonn.

This book contains select chapters on support vector algorithms from different perspectives, including mathematical background, properties of various kernel functions, and several applications. The main focus of this book is on orthogonal kernel functions, and the properties of the classical kernel functions-Chebyshev, Legendre, Gegenbauer, and Jacobi-are reviewed in some chapters. Moreover, the fractional form of these kernel functions is introduced in the same chapters, and for ease of use for these kernel functions, a tutorial on a Python package named ORSVM is presented. The book also exhibits a variety of applications for support vector algorithms, and in addition to the classification, these algorithms along with the introduced kernel functions are utilized for solving ordinary, partial, integro, and fractional differential equations. On the other hand, nowadays, the real-time and big data applications of support vector algorithms are growing. Consequently, the Compute Unified Device Architecture (CUDA) parallelizing the procedure of support vector algorithms based on orthogonal kernel functions is presented. The book sheds light on how to use support vector algorithms based on orthogonal kernel functions in different situations and gives a significant perspective to all machine learning and scientific machine learning researchers all around the world to utilize fractional orthogonal kernel functions in their pattern recognition or scientific computing problems.

Bayesian decision theory is known to provide an effective framework for the practical solution of discrete and nonconvex optimization problems. This book is the first to demonstrate that this framework is also well suited for the exploitation of heuristic methods in the solution of such problems, especially those of large scale for which exact optimization approaches can be prohibitively costly. The book covers all aspects ranging from the formal presentation of the Bayesian Approach, to its extension to the Bayesian Heuristic Strategy, and its utilization within the informal, interactive Dynamic Visualization strategy. The developed framework is applied in forecasting, in neural network optimization, and in a large number of discrete and continuous optimization problems. Specific application areas which are discussed include scheduling and visualization problems in chemical engineering, manufacturing process control, and epidemiology. Computational results and comparisons with a broad range of test examples are presented. The software required for implementation of the Bayesian Heuristic Approach is included. Although some knowledge of mathematical statistics is necessary in order to fathom the theoretical aspects of the development, no specialized mathematical knowledge is required to understand the application of the approach or to utilize the software which is provided. Audience: The book is of interest to both researchers in operations research, systems engineering, and optimization methods, as well as applications specialists concerned with the solution of large scale discrete and/or nonconvex optimization problems in a broad range of engineering and technological fields. It may be used as supplementary material for graduate level courses.

In a world with highly competitive markets and economic instability due to capitalization, industrial competition has increasingly intensified. In order for many industries to survive and succeed, they need to develop highly effective coordination between supply chain partners, dynamic collaborative and strategic alliance relationships, and efficient logistics and supply chain network designs. Consequently, in the past decade, there has been an explosion of interest among academic researchers and industrial practitioners in innovative supply chain and logistics models, algorithms, and coordination policies. Mathematically distinct from classical supply chain management, this emerging research area has been proven to be useful and applicable to a wide variety of industries. This book brings together recent advances in supply chain and logistics research and computational optimization that apply to a collaborative environment in the enterprise.

A lot of economic problems can be formulated as constrained optimizations and equilibration of their solutions. Various mathematical theories have been supplying economists with indispensable machineries for these problems arising in economic theory. Conversely, mathematicians have been stimulated by various mathematical difficulties raised by economic theories. The series is designed to bring together those mathematicians who are seriously interested in getting new challenging stimuli from economic theories with those economists who are seeking effective mathematical tools for their research.

This proceedings volume highlights the state-of-the-art knowledge related to optimization, decisions science and problem solving methods, as well as their application in industrial and territorial systems. It includes contributions tackling these themes using models and methods based on continuous and discrete optimization, network optimization, simulation and system dynamics, heuristics, metaheuristics, artificial intelligence, analytics, and also multiple-criteria decision making. The number and the increasing size of the problems arising in real life require mathematical models and solution methods adequate to their complexity. There has also been increasing research interest in Big Data and related challenges. These challenges can be recognized in many fields and systems which have a significant impact on our way of living: design, management and control of industrial production of goods and services; transportation planning and traffic management in urban and regional areas; energy production and exploitation; natural resources and environment protection; homeland security and critical infrastructure protection; development of advanced information and communication technologies. The chapters in this book examine how to deal with new and emerging practical problems arising in these different fields through the presented methodologies and their applications. The chapter topics are applicable for researchers and practitioners working in these areas, but also for the operations research community. The contributions were presented during the international conference "Optimization and Decision Science" (ODS2017), held at Hilton Sorrento Palace Conference Center, Sorrento, Italy, September 4 - 7, 2017. ODS 2017, was organized by AIRO, Italian Operations Research Society, in cooperation with DIETI (Department of Electrical Engineering and Information Technology) of University "Federico II" of Naples.

This book introduces the advances in synchromodal logistics and provides a framework to classify various optimisation problems in this field. It explores the application of this framework to solve a broad range of problems, such as problems with and without a central decision-maker, problems with and without full information, deterministic problems, problems coping with uncertainty, optimisation of a full network design problem. It covers theoretical constructs, such as discrete optimisation, robust optimisation, optimisation under uncertainty, multi-objective optimisation and agent based equilibrium models. Moreover, practical elaborated use cases are presented to deepen understanding. The book gives both researchers and practitioners a good overview of the field of synchromodal optimisation problems and offers the reader practical methods for modelling and problem-solving.

Using numerical examples to illustrate their concepts and results, this book examines recently developed fuzzy multi-criteria methods, such as Intuitionistic Fuzzy TOPSIS, Intuitionistic Fuzzy TOPSIS & DEA-AHP, Intuitionistic VIKOR, Pythagorean WASPAS, Pythagorean ENTROPI, Hesitant CBD, Hesitant MABAC, Triangular EDAS, Triangular PROMETHEE, q-Rung Orthopair COPRAS, and Fuzzy Type - 2 ELECTRE. Each chapter covers practical applications in addition to fresh developments and results. Given its structure and scope, the book can be used as a textbook in graduate courses on operations research and industrial engineering. It also offers a valuable resource for scientists working in a range of disciplines that require multi-criteria decision making.

This book deals with several types of multi-dimensional control problems in the face of data uncertainty for vector cases-multi-dimensional multi-objective control problem with uncertain objective functionals, uncertain constraint functionals, and uncertain objective as well as constraint functionals, uncertain multi-dimensional multi-objective control problem with semi-infinite constraints, uncertain dual multi-dimensional multi-objective variational control problem, and second-order PDE&PDI constrained robust optimization problem. The book provides the solution approaches-an exact l1 penalty function approach, modified objective approach, robust approach-in the simplest way to solve the recent developing optimization problems in the sense of uncertainty.

The effectiveness of the algorithms of linear programming in solving problems is largely dependent upon the particular applications from which these problems arise. A first course in linear programming should not only allow one to solve many different types of problems in many different contexts but should provide deeper insights into the fields in which linear programming finds its utility. To this end, the emphasis throughtout Linear Programming and Its Applications is on the acquisition of linear programming skills via the algorithmic solution of small-scale problems both in the general sense and in the specific applications where these problems naturally occur. The first part of the book deals with methods to solve general linear programming problems and discusses the theory of duality which connects these problems. The second part of the book deals with linear programming in different applications including the fields of game theory and graph theory as well as the more traditional transportation and assignment problems. The book is versatile; in as much as Linear Programming and Its Applications is intended to be used as a first course in linear programming, it is suitable for students in such varying fields as mathematics, computer science, engineering, actuarial science, and economics.

This classic on games and how to play them intelligently is being re-issued in a new, four volume edition. This book has laid the foundation to a mathematical approach to playing games. The wise authors wield witty words, which wangle wonderfully winning ways. In Volume 1, the authors do the Spade Work, presenting theories and techniques to "dissect" games of varied structures and formats in order to develop winning strategies.