Is specifically for MedTech entrepreneurs Covers all major steps in the development of a new medical device and bringing it to the market Analyzes product roadmap, common pitfalls, and factors, which can increase chances for success Discusses in each chapter a particular aspect of the MedDev startup roadmap: regulatory, fundraising, business model, IP protection Is primarily based on the US market but is also illustrated with examples from Europe and Canada

This book focuses on the modeling and analysis of heat and fluid flow in microchannels and micro-systems, compiling a number of analytical and hybrid numerical-analytical solutions for models that account for the relevant micro-scale effects, with the corresponding experimental analysis validation when applicable. The volume stands as the only available compilation of easy to use analytically-based solutions for micro-scale heat and fluid flow problems, that systematically incorporates the most relevant micro-scale effects into the mathematical models, followed by their physical interpretation on the micro-system behavior.

Advanced technologies such as robotics, 5G mobile communications, IoT, cloud computing and wireless sensor networks have had a huge impact and influence on manufacturing, with an increased collaboration between humans and smart systems. As the manufacturing process becomes more automated using real-time data, communication systems, Artificial Intelligence (AI) techniques and robotics feed data back into the manufacturing process. This enables the design of products that are more customized and personal, and leads to a more competitive, efficient and value-added production process by reacting more quickly to technical or human errors to avoid product and system damage while increasing workplace safety, and reducing waste, pollution, and associated costs. This edited book covers challenges, concepts, systems, architectures, technologies, and design characteristics of human-machine cooperation and interaction systems in smart manufacturing environments using state of the art technologies including AI, 5G, IoTs, Blockchains, CPS, sensing, automation and robotics. The book is aimed at researchers and engineers working on the applications of robotics and automation, HMI, HCI, CPS, sensing, information and communications technology, data science, ML/DL/AI, AR/VR, cybersecurity and electronics. It is also a useful reference for advanced students and lecturers in these fields, and will appeal to manufacturers and automation system developers.

Learn from these authors' experiences tailoring TPM to the disctinctive needs of North American plants, and how TPM fits into an overall manufacturing improvement strategy. A real-world view on what works and what doesn't, Robinson and Ginder provide and excellent resource for strategic planning and an educatioinal tool for middle and upper management. Includes the seven levels of autonomous maintenance, a discussion of unions and TPM, and a TPM master plan.

The pinball book you have been waiting for is finally here! From those fabulous '50s & '60s, Jeffrey Lawton, Bingo Pinball Historian, presents 290+ photos, including original promotional brochures and advertisements, that showcase a fantastic collection of Bally*r Bingo pinball machines, along with a history of the evolution and excitement that surrounds this compelling hobby. All who grew up with street cars, slot machines, pinball machines, pool halls, and diners will enjoy this book tremendously! If you buy only one pinball book, this is the one to have.

This book highlights some of the latest advances in nanotechnology and nanomaterials from leading researchers in Ukraine, Europe and beyond. It features contributions presented at the 7th International Science and Practice Conference Nanotechnology and Nanomaterials (NANO2019), which was held on August 27-30, 2019 at Lviv Polytechnic National University, and was jointly organized by the Institute of Physics of the National Academy of Sciences of Ukraine, University of Tartu (Estonia), University of Turin (Italy), and Pierre and Marie Curie University (France). Internationally recognized experts from a wide range of universities and research institutions share their knowledge and key findings on material properties, behavior, and synthesis. This book's companion volume also addresses topics such as nano-optics, energy storage, and biomedical applications.

The second edition of this book on nanomagnetism presents the basics and latest studies of low-dimensional magnetic nano-objects. It highlights the intriguing properties of nanomagnetic objects, such as thin films, nanoparticles, nanowires, nanotubes, nanodisks and nanorings as well as novel phenomena like spin currents. It also describes how nanomagnetism was an important factor in the rapid evolution of high-density magnetic recording and is developing into a decisive element of spintronics. Further, it presents a number of biomedical applications. With exercises and solutions, it serves as a graduate textbook.

This book highlights the proceedings of the International Conference on Atomic, Molecular, Optical and Nano-Physics with Applications (CAMNP 2019), organized by the Department of Applied Physics, Delhi Technological University, New Delhi, India. It presents experimental and theoretical studies of atoms, ions, molecules and nanostructures both at the fundamental level and on the application side using advanced technology. It highlights how modern tools of high-field and ultra-fast physics are no longer merely used to observe nature but can be used to reshape and redirect atoms, molecules, particles or radiation. It brings together leading researchers and professionals on the field to present and discuss the latest finding in the following areas, but not limited to: Atomic and Molecular Structure, Collision Processes, Data Production and Applications Spectroscopy of Solar and Stellar Plasma Intense Field, Short Pulse Laser and Atto-Second Physics Laser Technology, Quantum Optics and applications Bose Einstein condensation Nanomaterials and Nanoscience Nanobiotechnolgy and Nanophotonics Nano and Micro-Electronics Computational Condensed Matter Physics

Pressurized equipment is used for many industrial processes, for example in petrochemical plants, off-m,shore oil rigs, gas storage and control systems. In each case the pressure vessels must be carefully designed to cope with the operating temperatures and pressures. With the increasing service demands, quality requirements and safety legislation it has become vitally important for engineers to understand the fundamental principles underlying the methodologies of the design standards codes. This text provides background information on pressure vessel design for a wide range of pressurized components. It is written by engineers, the majority of whom serve on the British Standard Pressure Vessel Design Committee. The book derives from a series of courses and seminars run regularly in the UK and overseas by the University of Strathclyde in conjunction with the Institution of Mechanical Engineers since 1986. The scope and coverage has been developed over an extended period to meet the needs of those involved with pressure vessels as designers, fabricators, users, plant operators, inspection bodies, researchers and senior students.

This book presents experimental as well as simulation methodologies for analysis and development of nanostructures for introducing the desirable effects through modifications in the basic structure of select nanomaterials. The initial chapters in this book focus on exploring the basic aspects of nanomaterials, e.g., distinguishing features, synthesis, processing, characterization, simulation and application dimensions, or nanostructures that enable novel/enhanced properties or functions. The chapters also cover the size-dependent electronic, optical, and magnetic properties of nanomaterials in exposing the specific properties essential for applications in nanophotonics, nanoplasmonics, nanosystems (e.g., biological, medical, chemical, catalytic, energy, and environmental applications), and nanodevices (e.g., electronic, photonic, magnetic, imaging, diagnostic, and sensor applications). This book is a useful resource for students, researchers, and technologists in gathering recent knowledge on novel nanostructures and their use in different application areas.

This book highlights a comprehensive introduction of graphene and graphene-based two-dimensional nanomaterials, covering topics from their atomic structures, electronic band structures, and fundamental properties to technological applications. The book provides fundamental physics knowledge covering quantum mechanics, the theory of relativity, solid-state physics, and topology geometry necessary to understand electronic band structure of graphene. Other topics including microscopy techniques and preparation methods of graphene are also presented. Adopting an easy-to-read style, the book is a valuable resource for researchers in physics, chemistry, materials science, and engineers who are interested in the field of graphene-based nanomaterials.

The book presents cutting-edge research in the emerging fields of micro, nano and smart devices and systems from experts working in these fields over the last decade. Most of the contributors have built devices or systems or developed processes or algorithms in these areas. The book is a unique collection of chapters from different areas with a common theme and is immensely useful to academic researchers and practitioners in the industry who work in this field.

He's been called "America's greatest living tailor" and "the most interesting man in the world." Now, for the first time, Holocaust survivor Martin Greenfield tells his incredible life story. Taken from his Czechoslovakian home at age fifteen and transported to the Nazi concentration camp at Auschwitz with his family, Greenfield came face to face with "Angel of Death" Dr. Joseph Mengele and was divided forever from his parents, sisters, and baby brother. In haunting, powerful prose, Greenfield remembers his desperation and fear as a teenager alone in the death camp and how an SS soldier's shirt dramatically altered the course of his life. He learned how to sew; and when he began wearing the shirt under his prisoner uniform, he learned that clothes possess great power and could even help save his life. Measure of a Man is the story of a man who suffered unimaginable horror and emerged with a dream of success. From sweeping floors at a New York clothing factory to founding America's premier custom suit company, Greenfield built a fashion empire. Now 86 years old and working with his sons, Greenfield has dressed the famous and powerful of D.C. and Hollywood, including Presidents Dwight Eisenhower, Bill Clinton, and Barack Obama, celebrities Paul Newman, Leonardo DiCaprio, and Jimmy Fallon, and the stars of Martin Scorsese's films. Written with soul-baring honesty and, at times, a wry sense of humor, Measure of a Man is a memoir unlike any other one that will inspire hope and renew faith in the resilience of man.

Research and development of various parallel mechanism applications in engineering are now being performed more and more actively in every industrial field. Parallel robot based machine tools development is considered a key technology of robot applications in manufacturing industries. The material covered here describes the basic theory, approaches, and algorithms in the field of parallel robot based machine tools. In addition families of new alternative mechanical architectures which can be used for machine tools with parallel architecture are introduced. Given equal importance is the design of mechanism systems such as kinematic analysis, stiffness analysis, kinetostatic modeling, and optimization.

In a uniform and comprehensive manner the authors describe all the important aspects of the epitaxial growth processes of solid films on crystalline substrates, e.g. processes in which atoms of the growing film mimic the arrangement of the atoms of the substrate. Emphasis is put on sufficiently fundamental and unequivocal presentation of the subject in the form of an easy-to-read review. A large part of this book focuses on the problems of heteroepitaxy. The most important epitaxial growth techniques which are currently widely used in basic research as well as in manufacturing processes of devices are presented and discussed in detail.

This book presents the proceedings of the 4th International Conference of IFToMM ITALY (IFIT), held in Naples, Italy on September 7-9, 2022. It includes peer-reviewed papers on the latest advances in mechanism and machine science, discussing topics such as biomechanical engineering, computational kinematics, the history of mechanism and machine science, gearing and transmissions, multi-body dynamics, robotics and mechatronics, the dynamics of machinery, tribology, vibrations, rotor dynamics and vehicle dynamics. A valuable, up-to-date resource, it offers an essential overview of the subject for scientists and practitioners alike, and will inspire further investigations and research.

This book introduces the various aspects of the emerging field of carbon dots. Their structural and physico-chemical properties as well as their current and future potential applications are covered. A special chapter on graphene quantum dots is provided. The reader will also find different synthesis routes for carbon quantum dots.

CMOS Processors and Memories addresses the-state-of-the-art in integrated circuit design in the context of emerging computing systems. New design opportunities in memories and processor are discussed. Emerging materials that can take system performance beyond standard CMOS, like carbon nanotubes, graphene, ferroelectrics and tunnel junctions are explored.

CMOS Processors and Memories is divided into two parts: processors and memories. In the first part we start with high performance, low power processor design, followed by a chapter on multi-core processing. They both represent state-of-the-art concepts in current computing industry. The third chapter deals with asynchronous design that still carries lots of promise for future computing needs. At the end we present a "hardware design space exploration" methodology for implementing and analyzing the hardware for the Bayesian inference framework. This particular methodology involves: analyzing the computational cost and exploring candidate hardware components, proposing various custom architectures using both traditional CMOS and hybrid nanotechnology CMOL. The first part concludes with hybrid CMOS-Nano architectures.

The second, memory part covers state-of-the-art SRAM, DRAM, and flash memories as well as emerging device concepts. Semiconductor memory is a good example of the full custom design that applies various analog and logic circuits to utilize the memory cell's device physics. Critical physical effects that include tunneling, hot electron injection, charge trapping (Flash memory) are discussed in detail. Emerging memories like FRAM, PRAM and ReRAM that depend on magnetization, electron spin alignment, ferroelectric effect, built-in potential well, quantum effects, and thermal melting are also described.

CMOS Processors and Memories is a must for anyone serious about circuit design for future computing technologies. The book is written by top notch international experts in industry and academia. It can be used in graduate course curriculum.

This book reviews the work in the field of nanoadsorbents derived from natural polymers, with a special emphasis on materials finding application in water remediation. It includes natural materials both with an organic or an inorganic skeleton, from which the nanomaterials can be made. Those nanomaterials can therefore be used to reinforce other matrices and in their pristine form have an extraordinary adsorption efficiency. Being of natural or biological origin, the materials described in this book distinguish themselves as eco-friendly and non-toxic. The book describes how these benefits of the described materials can be combined and exploited. It will thus appeal to chemists, nanotechnologists, environmental engineers and generally all scientist working in the field of water pollution and remediation as an inspiration for the innovation toward new technologies.

Lean Manufacturing concepts are being applied to a variety of industries. These concepts ensure streamlined processes through a systematic analysis of wastes and elimination, while enhancing value. This book offers fundamentals, theoretical concepts, case studies, and examples, along with insights for lean integration in Industry 4.0. The book offers a comprehensive coverage of topics in Lean Manufacturing which includes lean elements and tools, performance measures, project selection, integration, along with other related strategies. It ensures a balance between theory and practice of Lean Manufacturing by including the implementation aspects of lean tools. The book will explore insights for Industry 4.0 related to lean concepts and provide details on how they relate. Illustrations and examples depicting OEE (Overall Equipment Effectiveness) analysis and value stream map analysis are included. The book also provides case studies on Lean Manufacturing covering value stream mapping, project selection, and performance measurement. Lean Manufacturing: Fundamentals, Tools, Approaches, and Industry 4.0 Integration can be used as a reference for academic researchers and industry practitioners. Undergraduate and postgraduate students can use it for a course on Lean Manufacturing. Doctoral students can also refer to it for advanced concepts, and industry practitioners can use it for practical insights.

In Leading Lean by Living Lean, Philip Holt details and explains what is probably the most important part of becoming a Lean Leader -- living and practicing what you preach. To do this you must believe in what you're doing, understand what it means and what you need to do, and do it every day. The author, through his engineering background, has fully embraced the Plan-Do-Check-Act (PDCA) model of Deming / Shewhart but has adapted David Bovis' Believe-Think-Feel-Act (BTFA) model to understand why logic and facts are very often not the principal players in the game of change. In this book, Holt author describes how you can take both the PDCA and BTFA models into account and has sectioned the book into three prime parts: 1. Head -- How you learn and understand the Lean principles and their application. 2. Hands -- How you practice Lean Leadership daily. 3. Heart -- How you internalize and believe in Lean Leadership. Through this book, you, the Lean practitioner, whether aspiring or experienced, will have everything that you need to "lead it," "do it," and "live it." The nature of this book is more "why to" than "how to" - the author knows that he cannot tell you how to lead, do, or live Lean; he can only explain why it is so important and share his knowledge, experiences, failures, and successes. This book isn't so much a self-help book as a self-reflection book and it can point you in the proper direction, but... the book won't change you; only you can change you! Essentially, with this book, the author wants those who think of Lean as a toolkit, who believe that Lean can be project managed, or who argue about Lean versus Six Sigma and misunderstand the fundamental depth of impact that true Lean Leadership has on an organization to be disabused of any or all of those notions. This book is aimed at those leaders who seek to experience the full transformative effects of Lean in their organizations and want to practice it at the principle level of deployment. Holt's aim is to help business leaders enhance who they are by changing what they do and the way that they do it

Now in a thoroughly revised second edition, this practical practitioner guide provides a comprehensive overview of the SoC design process. It explains end-to-end system on chip (SoC) design processes and includes updated coverage of design methodology, the design environment, EDA tool flow, design decisions, choice of design intellectual property (IP) cores, sign-off procedures, and design infrastructure requirements. The second edition provides new information on SOC trends and updated design cases. Coverage also includes critical advanced guidance on the latest UPF-based low power design flow, challenges of deep submicron technologies, and 3D design fundamentals, which will prepare the readers for the challenges of working at the nanotechnology scale. A Practical Approach to VLSI System on Chip (SoC) Design: A Comprehensive Guide, Second Edition provides engineers who aspire to become VLSI designers with all the necessary information and details of EDA tools. It will be a valuable professional reference for those working on VLSI design and verification portfolios in complex SoC designs

This comprehensive reference work gives an overview of the industrial development and current state of industrialization and deindustrialization in Asia, specifically Southeast Asia and China. It introduces typologies of industrial policies and discusses the manufacturing sector and its evolving role in the region. Designing Integrated Industrial Policies examines the integration of SMEs in global value chains and provides macro-econometric and firm-based micro-econometric analyses of (de)industrialization. This book will be a very useful reference particularly as a how-to guide on industrial promotion and designing integrated industrial policies not only for economic growth and job creation but also for "inclusive" development. It presents country cases and illustrates useful tools for industrial policy simulation and for evidence-based policy making through these concrete examples.

This volume focuses on the fundamentals and advancements in micro and nanomanufacturing technologies applied in the biomedical and biochemical domain. The contents of this volume provide comprehensive coverage of the physical principles of advanced manufacturing technologies and the know-how of their applications in the fabrication of biomedical devices and systems. The book begins by documenting the journey of miniaturization and micro-and nano-fabrication. It then delves into the fundamentals of various advanced technologies such as micro-wire moulding, 3D printing, lithography, imprinting, direct laser machining, and laser-induced plasma-assisted machining. It also covers laser-based technologies which are a promising option due to their flexibility, ease in control and application, high precision, and availability. These technologies can be employed to process several materials such as glass, polymers: polycarbonate, polydimethylsiloxane, polymethylmethacrylate, and metals such as stainless steel, which are commonly used in the fabrication of biomedical devices, such as microfluidic technology, optical and fiber-optic sensors, and electro-chemical bio-sensors. It also discusses advancements in various MEMS/NEMS based technologies and their applications in energy conversion and storage devices. The chapters are written by experts from the fields of micro- and nano-manufacturing, materials engineering, nano-biotechnology, and end-users such as clinicians, engineers, academicians of interdisciplinary background. This book will be a useful guide for academia and industry alike.

This book reflects the current status of theoretical and experimental research of graphene based nanostructures, in particular quantum dots, at a level accessible to young researchers, graduate students, experimentalists and theorists. It presents the current state of research of graphene quantum dots, a single or few monolayer thick islands of graphene. It introduces the reader to the electronic and optical properties of graphite, intercalated graphite and graphene, including Dirac fermions, Berry's phase associated with sublattices and valley degeneracy, covers single particle properties of graphene quantum dots, electron-electron interaction, magnetic properties and optical properties of gated graphene nanostructures. The electronic, optical and magnetic properties of the graphene quantum dots as a function of size, shape, type of edge and carrier density are considered. Special attention is paid to the understanding of edges and the emergence of edge states for zigzag edges. Atomistic tight binding and effective mass approaches to single particle calculations are performed. Furthermore, the theoretical and numerical treatment of electron-electron interactions at the mean-field, HF, DFT and configuration-interaction level is described in detail.