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Books > Science & Mathematics > Mathematics > Probability & statistics

Linear Mixed Models - A Practical Guide Using Statistical Software (Hardcover, 3rd edition): Brady T. West, Kathleen B. Welch,... Linear Mixed Models - A Practical Guide Using Statistical Software (Hardcover, 3rd edition)
Brady T. West, Kathleen B. Welch, Andrzej T. Galecki
R2,777 Discovery Miles 27 770 Ships in 9 - 15 working days

Highly recommended by JASA, Technometrics, and other leading statistical journals, the first two editions of this bestseller showed how to easily perform complex linear mixed model (LMM) analyses via a variety of software programs. Linear Mixed Models: A Practical Guide Using Statistical Software, Third Edition continues to lead readers step-by-step through the process of fitting LMMs. The third edition provides a comprehensive update of the available tools for fitting linear mixed-effects models in the newest versions of SAS, SPSS, R, Stata, and HLM. All examples have been updated, with a focus on new tools for visualization of results and interpretation. New conceptual and theoretical developments in mixed-effects modeling have been included, and there is a new chapter on power analysis for mixed-effects models. Features:*Dedicates an entire chapter to the key theories underlying LMMs for clustered, longitudinal, and repeated measures data *Provides descriptions, explanations, and examples of software code necessary to fit LMMs in SAS, SPSS, R, Stata, and HLM *Contains detailed tables of estimates and results, allowing for easy comparisons across software procedures *Presents step-by-step analyses of real-world data sets that arise from a variety of research settings and study designs, including hypothesis testing, interpretation of results, and model diagnostics *Integrates software code in each chapter to compare the relative advantages and disadvantages of each package *Supplemented by a website with software code, datasets, additional documents, and updates Ideal for anyone who uses software for statistical modeling, this book eliminates the need to read multiple software-specific texts by covering the most popular software programs for fitting LMMs in one handy guide. The authors illustrate the models and methods through real-world examples that enable comparisons of model-fitting options and results across the software procedures.

Data Science and Analytics Strategy - An Emergent Design Approach (Paperback): Kailash Awati, Alexander Scriven Data Science and Analytics Strategy - An Emergent Design Approach (Paperback)
Kailash Awati, Alexander Scriven
R1,355 Discovery Miles 13 550 Ships in 9 - 15 working days

Written for professionals looking to build data science and analytics capabilities within their organizations as well as those who wish to expand their knowledge and advance their careers in the data space Shows how to build a fit-for-purpose data science capability in a manner that avoids the most common pitfalls Most data strategy works 'top-down' by providing technical solutions to perceived organizational needs. This book uses emergent design, an evolutionary approach that increases the chances of successful outcomes while minimising upfront investment

Statistics for People Who (Think They) Hate Statistics (Paperback, 7th ed.): Neil J Salkind, Bruce B. Frey Statistics for People Who (Think They) Hate Statistics (Paperback, 7th ed.)
Neil J Salkind, Bruce B. Frey
R3,715 Discovery Miles 37 150 Ships in 10 - 15 working days

Now in its Seventh Edition, Neil J. Salkind's bestselling Statistics for People Who (Think They) Hate Statistics with new co-author Bruce B. Frey teaches an often intimidating subject with a humorous, personable, and informative approach that reduces statistics anxiety. With instruction in SPSS(R), the authors guide students through basic and advanced statistical procedures, from correlation and graph creation to analysis of variance, regression, non-parametric tests, and more. The Seventh Edition includes new real-world examples, additional coverage on multiple regression and power and effect size, and a robust interactive eBook with video tutorials and animations of key concepts. In the end, students who (think they) hate statistics will understand how to explain the results of many statistical analyses and won't be intimidated by basic statistical tasks.

An Adventure in Statistics - The Reality Enigma (Paperback, 2nd Revised edition): Andy Field An Adventure in Statistics - The Reality Enigma (Paperback, 2nd Revised edition)
Andy Field
R1,146 Discovery Miles 11 460 Ships in 12 - 17 working days

Shortlisted for the British Psychological Society Book Award 2017 Shortlisted for the British Book Design and Production Awards 2016 Shortlisted for the Association of Learned & Professional Society Publishers Award for Innovation in Publishing 2016 Now in its second edition, An Adventure in Statistics: The Reality Enigma by best-selling author and award-winning teacher Andy Field offers a better way to learn statistics. It combines rock-solid statistics coverage with compelling visual storytelling to address the conceptual difficulties that students learning statistics for the first time often encounter in introductory courses. Students are guided away from rote memorization towards independent, critical thinking and problem solving. This essential foundation to understanding statistics is woven into the unique action-packed story of Zach, who thinks, processes information and faces challenges to his understanding in the same way as a statistics novice. Illustrated with stunning, graphic novel-style art and featuring Socratic dialogue, the story captivates readers as it introduces them to concepts, eliminating potential statistics anxiety. No previous statistics knowledge is presumed, and no use of data analysis software is required - everything you would expect for an introductory course is covered but with a contemporary twist, arming students with a strong grounding in understanding classical and Bayesian approaches to data analysis. With its unique combination of story, concepts and terminology, this complete introduction to statistics from bestselling author Andy Field breaks the mould to present a statistical tale like no other. Stay connected Join us on Facebook and share your experiences with Andy's texts, check out news, access free stuff, see photos, watch videos, learn about competitions, and much more.

Data-Driven Science and Engineering - Machine Learning, Dynamical Systems, and Control (Hardcover, 2nd Revised edition): Steven... Data-Driven Science and Engineering - Machine Learning, Dynamical Systems, and Control (Hardcover, 2nd Revised edition)
Steven L. Brunton, J. Nathan Kutz
R1,720 R1,624 Discovery Miles 16 240 Save R96 (6%) Ships in 12 - 17 working days

Data-driven discovery is revolutionizing how we model, predict, and control complex systems. Now with Python and MATLAB (R), this textbook trains mathematical scientists and engineers for the next generation of scientific discovery by offering a broad overview of the growing intersection of data-driven methods, machine learning, applied optimization, and classical fields of engineering mathematics and mathematical physics. With a focus on integrating dynamical systems modeling and control with modern methods in applied machine learning, this text includes methods that were chosen for their relevance, simplicity, and generality. Topics range from introductory to research-level material, making it accessible to advanced undergraduate and beginning graduate students from the engineering and physical sciences. The second edition features new chapters on reinforcement learning and physics-informed machine learning, significant new sections throughout, and chapter exercises. Online supplementary material - including lecture videos per section, homeworks, data, and code in MATLAB (R), Python, Julia, and R - available on databookuw.com.

Network Psychometrics with R - A Guide for Behavioral and Social Scientists (Paperback): Adela-Maria Isvoranu, Sacha Epskamp,... Network Psychometrics with R - A Guide for Behavioral and Social Scientists (Paperback)
Adela-Maria Isvoranu, Sacha Epskamp, Lourens Waldorp, Denny Borsboom
R1,606 Discovery Miles 16 060 Ships in 9 - 15 working days

A systematic, innovative introduction to the field of network analysis, Network Psychometrics with R: A Guide for Behavioral and Social Scientists provides a comprehensive overview of and guide to both the theoretical foundations of network psychometrics as well as modelling techniques developed from this perspective. Written by pioneers in the field, this textbook showcases cutting-edge methods in an easily accessible format, accompanied by problem sets and code. After working through this book, readers will be able to understand the theoretical foundations behind network modelling, infer network topology, and estimate network parameters from different sources of data. This book features an introduction on the statistical programming language R that guides readers on how to analyse network structures and their stability using R. While Network Psychometrics with R is written in the context of social and behavioral science, the methods introduced in this book are widely applicable to data sets from related fields of study. Additionally, while the text is written in a non-technical manner, technical content is highlighted in textboxes for the interested reader. Network Psychometrics with R is ideal for instructors and students of undergraduate and graduate level courses and workshops in the field of network psychometrics as well as established researchers looking to master new methods. This book is accompanied by a companion website with resources for both students and lecturers.

An Introduction to Latent Variable Growth Curve Modeling - Concepts, Issues, and Application, Second Edition (Paperback, 2nd... An Introduction to Latent Variable Growth Curve Modeling - Concepts, Issues, and Application, Second Edition (Paperback, 2nd edition)
Terry E. Duncan, Susan C. Duncan, Lisa A. Strycker
R1,568 Discovery Miles 15 680 Ships in 9 - 15 working days

This book provides a comprehensive introduction to latent variable growth curve modeling (LGM) for analyzing repeated measures. It presents the statistical basis for LGM and its various methodological extensions, including a number of practical examples of its use. It is designed to take advantage of the reader's familiarity with analysis of variance and structural equation modeling (SEM) in introducing LGM techniques. Sample data, syntax, input and output, are provided for EQS, Amos, LISREL, and Mplus on the book's CD. Throughout the book, the authors present a variety of LGM techniques that are useful for many different research designs, and numerous figures provide helpful diagrams of the examples.
Updated throughout, the second edition features three new chapters--growth modeling with ordered categorical variables, growth mixture modeling, and pooled interrupted time series LGM approaches. Following a new organization, the book now covers the development of the LGM, followed by chapters on multiple-group issues (analyzing growth in multiple populations, accelerated designs, and multi-level longitudinal approaches), and then special topics such as missing data models, LGM power and Monte Carlo estimation, and latent growth interaction models. The model specifications previously included in the appendices are now available on the CD so the reader can more easily adapt the models to their own research.
This practical guide is ideal for a wide range of social and behavioral researchers interested in the measurement of change over time, including social, developmental, organizational, educational, consumer, personality and clinical psychologists, sociologists, and quantitativemethodologists, as well as for a text on latent variable growth curve modeling or as a supplement for a course on multivariate statistics. A prerequisite of graduate level statistics is recommended.

Sparse Graphical Modeling for High Dimensional Data - A Paradigm of Conditional Independence Tests (Hardcover): Faming Liang,... Sparse Graphical Modeling for High Dimensional Data - A Paradigm of Conditional Independence Tests (Hardcover)
Faming Liang, Bochao Jia
R2,777 Discovery Miles 27 770 Ships in 9 - 15 working days

This book provides a general framework for learning sparse graphical models with conditional independence tests. It includes complete treatments for Gaussian, Poisson, multinomial, and mixed data; unified treatments for covariate adjustments, data integration, and network comparison; unified treatments for missing data and heterogeneous data; efficient methods for joint estimation of multiple graphical models; effective methods of high-dimensional variable selection; and effective methods of high-dimensional inference. The methods possess an embarrassingly parallel structure in performing conditional independence tests, and the computation can be significantly accelerated by running in parallel on a multi-core computer or a parallel architecture. This book is intended to serve researchers and scientists interested in high-dimensional statistics, and graduate students in broad data science disciplines. Key Features: A general framework for learning sparse graphical models with conditional independence tests Complete treatments for different types of data, Gaussian, Poisson, multinomial, and mixed data Unified treatments for data integration, network comparison, and covariate adjustment Unified treatments for missing data and heterogeneous data Efficient methods for joint estimation of multiple graphical models Effective methods of high-dimensional variable selection Effective methods of high-dimensional inference

Introduction to Python for Humanists (Paperback): William Mattingly Introduction to Python for Humanists (Paperback)
William Mattingly
R1,462 Discovery Miles 14 620 Ships in 9 - 15 working days

This book will introduce digital humanists at all levels of education to Python. It provides background and guidance on learning the Python computer programming language, and as it presumes no knowledge on the part of the reader about computers or coding concepts allows the reader to gradually learn the more complex tasks that are currently popular in the field of digital humanities. This book will be aimed at undergraduates, graduates, and faculty who are interested in learning how to use Python as a tool within their workflow. An Introduction to Python for Digital Humanists will act as a primer for students who wish to use Python, allowing them to engage with more advanced textbooks. This book fills a real need, as it is first Python introduction to be aimed squarely at humanities students, as other books currently available do not approach Python from a humanities perspective. It will be designed so that those experienced in Python can teach from it, in addition to allowing those who are interested in being self-taught can use it for that purpose. Key Features: Data analysis Data science Computational humanities Digital humanities Python Natural language processing Social network analysis App development

Nonparametric Statistical Methods Using R (Hardcover): John Kloke, Joseph W. McKean Nonparametric Statistical Methods Using R (Hardcover)
John Kloke, Joseph W. McKean
R2,657 Discovery Miles 26 570 Ships in 12 - 17 working days

A Practical Guide to Implementing Nonparametric and Rank-Based Procedures Nonparametric Statistical Methods Using R covers traditional nonparametric methods and rank-based analyses, including estimation and inference for models ranging from simple location models to general linear and nonlinear models for uncorrelated and correlated responses. The authors emphasize applications and statistical computation. They illustrate the methods with many real and simulated data examples using R, including the packages Rfit and npsm. The book first gives an overview of the R language and basic statistical concepts before discussing nonparametrics. It presents rank-based methods for one- and two-sample problems, procedures for regression models, computation for general fixed-effects ANOVA and ANCOVA models, and time-to-event analyses. The last two chapters cover more advanced material, including high breakdown fits for general regression models and rank-based inference for cluster correlated data. The book can be used as a primary text or supplement in a course on applied nonparametric or robust procedures and as a reference for researchers who need to implement nonparametric and rank-based methods in practice. Through numerous examples, it shows readers how to apply these methods using R.

Statistics (Paperback): David Freedman, Robert Pisani, Roger Purves Statistics (Paperback)
David Freedman, Robert Pisani, Roger Purves
R1,029 Discovery Miles 10 290 Ships in 12 - 17 working days
Multivariate Data Analysis (Paperback, 8th edition): Joseph Hair, William Black, Rolph Anderson, Barry Babin Multivariate Data Analysis (Paperback, 8th edition)
Joseph Hair, William Black, Rolph Anderson, Barry Babin
R1,282 R1,155 Discovery Miles 11 550 Save R127 (10%) Ships in 10 - 15 working days

For over 30 years, this text has provided students with the information they need to understand and apply multivariate data analysis. The eighth edition of Multivariate Data Analysis provides an updated perspective on the analysis of all types of data as well as introducing some new perspectives and techniques that are foundational in today's world of analytics. Multivariate Data Analysis serves as the perfect companion for graduate and postgraduate students undertaking statistical analysis for business degrees, providing an application-oriented introduction to multivariate analysis for the non-statistician. By reducing heavy statistical research into fundamental concepts, the text explains to students how to understand and make use of the results of specific statistical techniques.

Statistics for People Who (Think They) Hate Statistics - International Student Edition - Using Microsoft Excel (Paperback, 5th... Statistics for People Who (Think They) Hate Statistics - International Student Edition - Using Microsoft Excel (Paperback, 5th Revised edition)
Neil J Salkind, Bruce B. Frey
R1,791 Discovery Miles 17 910 Ships in 12 - 17 working days

This Fifth Edition of Neil J. Salkind's Statistics for People Who (Think They) Hate Statistics: Using Microsoft Excel, presents an often intimidating and difficult subject in a way that is clear, informative, and personable. Opening with an introduction to Excel, including coverage of how to use functions and formulas, this edition shows students how to install the Excel Data Analysis Tools option to access a host of useful analytical techniques. New to the Fifth Edition is new co-author Bruce Frey who has added a new feature on statisticians throughout history (with a focus on the contributions of women and people of color). He has updated the "Real-World Stats" feature, and added more on effect sizes, updated the discussions on hypotheses, measurement concepts like validity and reliability, and has more closely tied analytical choices to the level of measurement of variables.

Data Visualization in Excel - A Guide for Beginners, Intermediates, and Wonks (Hardcover): Jonathan Schwabish Data Visualization in Excel - A Guide for Beginners, Intermediates, and Wonks (Hardcover)
Jonathan Schwabish
R2,339 Discovery Miles 23 390 Ships in 12 - 17 working days

This is the first book available on the market that shows people how to create more advanced data visualizations in the Excel software tool. It provides step-by-step instructions and downloadable Excel files, that readers can use to expand how they use Excel and communicate their data to their audiences.

Generalized Linear Mixed Models - Modern Concepts, Methods and Applications (Hardcover, New): Walter W. Stroup Generalized Linear Mixed Models - Modern Concepts, Methods and Applications (Hardcover, New)
Walter W. Stroup
R3,055 Discovery Miles 30 550 Ships in 12 - 17 working days

Generalized Linear Mixed Models: Modern Concepts, Methods and Applications presents an introduction to linear modeling using the generalized linear mixed model (GLMM) as an overarching conceptual framework. For readers new to linear models, the book helps them see the big picture. It shows how linear models fit with the rest of the core statistics curriculum and points out the major issues that statistical modelers must consider. Along with describing common applications of GLMMs, the text introduces the essential theory and main methodology associated with linear models that accommodate random model effects and non-Gaussian data. Unlike traditional linear model textbooks that focus on normally distributed data, this one adopts a generalized mixed model approach throughout: data for linear modeling need not be normally distributed and effects may be fixed or random. With numerous examples using SAS (R) PROC GLIMMIX, this book is ideal for graduate students in statistics, statistics professionals seeking to update their knowledge, and researchers new to the generalized linear model thought process. It focuses on data-driven processes and provides context for extending traditional linear model thinking to generalized linear mixed modeling. See Professor Stroup discuss the book.

Simply Maths (Hardcover): Dk Simply Maths (Hardcover)
Dk
R150 R120 Discovery Miles 1 200 Save R30 (20%) Ships in 5 - 10 working days

Understanding maths has never been easier. Combining bold, elegant graphics with easy-to-understand text, Simply Maths is the perfect introduction to the subject for those who are short of time but hungry for knowledge. Covering more than 90 key mathematical concepts from prime numbers and fractions to quadratic equations and probability experiments, each pared-back, single-page entry explains the concept more clearly than ever before. Organized by major themes - number theory and systems; calculations; geometry; algebra; graphs; ratio and proportion; measurement; probability and statistics; and calculus - entries explain the essentials of each key mathematical theory with simple clarity and for ease of understanding. Whether you are studying maths at school or college, or simply want a jargon-free overview of the subject, this indispensable guide is packed with everything you need to understand the basics quickly and easily.

Advanced Probability and Statistics - Applications to Physics and Engineering (Hardcover): Harish Parthasarathy Advanced Probability and Statistics - Applications to Physics and Engineering (Hardcover)
Harish Parthasarathy
R3,801 Discovery Miles 38 010 Ships in 9 - 15 working days

This book surveys some of the important research work carried out by Indian scientists in the field of pure and applied probability, quantum probability, quantum scattering theory, group representation theory and general relativity. It reviews the axiomatic foundations of probability theory by A.N. Kolmogorov and how the Indian school of probabilists and statisticians used this theory effectively to study a host of applied probability and statistics problems like parameter estimation, convergence of a sequence of probability distributions, and martingale characterization of diffusions. It will be an important resource to students and researchers of Physics and Engineering, especially those working with Advanced Probability and Statistics.

Student Solutions Manual for Scheaffer/Mendenhall/Ott/Gerow's  Elementary Survey Sampling (Paperback, 7th Revised... Student Solutions Manual for Scheaffer/Mendenhall/Ott/Gerow's Elementary Survey Sampling (Paperback, 7th Revised edition)
Richard Scheaffer
R2,247 R1,950 Discovery Miles 19 500 Save R297 (13%) Ships in 10 - 15 working days

This manual contains fully worked-out solutions to selected problems from the text.

ANOVA and Mixed Models - A Short Introduction Using R (Hardcover): Lukas Meier ANOVA and Mixed Models - A Short Introduction Using R (Hardcover)
Lukas Meier
R4,061 Discovery Miles 40 610 Ships in 9 - 15 working days

Features Accessible to readers with a basic background in probability and statistics Covers fundamental concepts of experimental design and cause-effect relationships Introduces classical ANOVA models, including contrasts and multiple testing Provides an example-based introduction to mixed models Features basic concepts of split-plot and incomplete block designs R code available for all steps Supplementary website with additional resources and updates

AI for Finance (Hardcover): Edward P K Tsang AI for Finance (Hardcover)
Edward P K Tsang
R3,595 Discovery Miles 35 950 Ships in 9 - 15 working days

How could Finance benefit from AI? How can AI techniques provide an edge? Moving well beyond simply speeding up computation, this book tackles AI for Finance from a range of perspectives including business, technology, research, and students. Covering aspects like algorithms, big data, and machine learning, this book answers these and many other questions.

How the World Really Works - The Science Behind How We Got Here and Where We're Going (Hardcover): Vaclav Smil How the World Really Works - The Science Behind How We Got Here and Where We're Going (Hardcover)
Vaclav Smil
R819 R626 Discovery Miles 6 260 Save R193 (24%) Ships in 10 - 15 working days

INSTANT NEW YORK TIMES BESTSELLER "A new masterpiece from one of my favorite authors... [How The World Really Works] is a compelling and highly readable book that leaves readers with the fundamental grounding needed to help solve the world's toughest challenges."-Bill Gates "Provocative but perceptive . . . You can agree or disagree with Smil-accept or doubt his 'just the facts' posture-but you probably shouldn't ignore him."-The Washington Post An essential analysis of the modern science and technology that makes our twenty-first century lives possible-a scientist's investigation into what science really does, and does not, accomplish. We have never had so much information at our fingertips and yet most of us don't know how the world really works. This book explains seven of the most fundamental realities governing our survival and prosperity. From energy and food production, through our material world and its globalization, to risks, our environment and its future, How the World Really Works offers a much-needed reality check-because before we can tackle problems effectively, we must understand the facts. In this ambitious and thought-provoking book we see, for example, that globalization isn't inevitable-the foolishness of allowing 70 per cent of the world's rubber gloves to be made in just one factory became glaringly obvious in 2020-and that our societies have been steadily increasing their dependence on fossil fuels, such that any promises of decarbonization by 2050 are a fairy tale. For example, each greenhouse-grown supermarket-bought tomato has the equivalent of five tablespoons of diesel embedded in its production, and we have no way of producing steel, cement or plastics at required scales without huge carbon emissions. Ultimately, Smil answers the most profound question of our age: are we irrevocably doomed or is a brighter utopia ahead? Compelling, data-rich and revisionist, this wonderfully broad, interdisciplinary guide finds faults with both extremes. Looking at the world through this quantitative lens reveals hidden truths that change the way we see our past, present and uncertain future.

Statistical Thinking for Non-Statisticians in Drug  Regulation, 2e (Hardcover, 2nd Edition): RR Kay Statistical Thinking for Non-Statisticians in Drug Regulation, 2e (Hardcover, 2nd Edition)
RR Kay
R2,050 R1,799 Discovery Miles 17 990 Save R251 (12%) Ships in 7 - 13 working days

Statistical Thinking for Non-Statisticians in Drug Regulation, Second Edition, is a need-to-know guide to understanding statistical methodology, statistical data and results within drug development and clinical trials. It provides non-statisticians working in the pharmaceutical and medical device industries with an accessible introduction to the knowledge they need when working with statistical information and communicating with statisticians. It covers the statistical aspects of design, conduct, analysis and presentation of data from clinical trials in drug regulation and improves the ability to read, understand and critically appraise statistical methodology in papers and reports. As such, it is directly concerned with the day-to-day practice and the regulatory requirements of drug development and clinical trials. Fully conversant with current regulatory requirements, this second edition includes five new chapters covering Bayesian statistics, adaptive designs, observational studies, methods for safety analysis and monitoring and statistics for diagnosis. Authored by a respected lecturer and consultant to the pharmaceutical industry, Statistical Thinking for Non-Statisticians in Drug Regulation is an ideal guide for physicians, clinical research scientists, managers and associates, data managers, medical writers, regulatory personnel and for all non-statisticians working and learning within the pharmaceutical industry.

Real World AI Ethics for Data Scientists - Practical Case Studies (Paperback): Nachshon (Sean) Goltz, Tracey Dowdeswell Real World AI Ethics for Data Scientists - Practical Case Studies (Paperback)
Nachshon (Sean) Goltz, Tracey Dowdeswell
R1,342 Discovery Miles 13 420 Ships in 9 - 15 working days

Designed to offer an accessible set of case studies and analyses of ethical dilemmas in data science. This book will be suitable for technical readers in data science who want to understand diverse ethical approaches to AI.

Advanced Computational Techniques for Sustainable Computing (Hardcover): Megha Rathi, Adwitiya Sinha Advanced Computational Techniques for Sustainable Computing (Hardcover)
Megha Rathi, Adwitiya Sinha
R4,521 Discovery Miles 45 210 Ships in 9 - 15 working days

Provides insight on building smart sustainable solutions Includes details of applying mining, learning, IOT and sensor-based techniques for sustainable computing Entails data extraction from various sources followed with pre-processing of data, and how to make effective use of extracted data for application-based research Involves practical usage of data analytic language, including R, Python, etc. for improving sustainable services offered by multi-disciplinary domains Encompasses comparison and analysis of recent technologies and trends Includes development of smart models for information gain and effective decision making with visualization

Sample Sizes for Clinical Trials (Hardcover, 2nd edition): Steven A. Julious Sample Sizes for Clinical Trials (Hardcover, 2nd edition)
Steven A. Julious
R2,794 Discovery Miles 27 940 Ships in 9 - 15 working days

Sample Sizes for Clinical Trials, Second Edition is a practical book that assists researchers in their estimation of the sample size for clinical trials. Throughout the book there are detailed worked examples to illustrate both how to do the calculations and how to present them to colleagues or in protocols. The book also highlights some of the pitfalls in calculations as well as the key steps that lead to the final sample size calculation. Features: Comprehensive coverage of sample size calculations, including Normal, binary, ordinal, and survival outcome data Covers superiority, equivalence, non-inferiority, bioequivalence and precision objectives for both parallel group and crossover designs Highlights how trial objectives impact the study design with respect to both the derivation of sample formulae and the size of the study Motivated with examples of real-life clinical trials showing how the calculations can be applied New edition is extended with all chapters revised, some substantially, and four completely new chapters on multiplicity, cluster trials, pilot studies, and single arm trials The book is primarily aimed at researchers and practitioners of clinical trials and biostatistics, and could be used to teach a course on sample size calculations. The importance of a sample size calculation when designing a clinical trial is highlighted in the book. It enables readers to quickly find an appropriate sample size formula, with an associated worked example, complemented by tables to assist in the calculations.

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