Biomedical EPR - Part A focuses on applications of EPR spectroscopy in the areas of free radicals, metals, medicine, and physiology. The book celebrates the 70th birthday of Prof. James S. Hyde, Medical College of Wisconsin, and his contributions to this field. Chapters are written to provide introductory material for new-comers to the field which lead into up-to-date reviews that provide perspective on the wide range of questions that can be addressed by EPR.

Key Features:
Free Radicals in Medicine

Radicals in vivo and in Model Systems, and their Study by Spin Trapping

In vivo EPR, including Oximetry and Imaging

Time Domain EPR at Radio Frequencies

EPR of Copper Complexes: Motion and Frequency Dependence

Time Domain EPR and Electron Spin Echo Envelope Modulation

- 'Big' book has sold close to 1400 in just over a year and is maintaining high rate of sale.

- This practical handbook fully explains the essentials of this state-of-the-art technique to radiologists, gastroenterologists, radiology residents, and technologists.

- Makes the key chapters of the big book accessible and affordable to the resident.

PACS: A Guide to the Digital Revolution, Second Edition, fills an incredible need by explaining the technological advances associated with the transition of radiology departments to filmless environments. The editors are leaders in the field of medical imaging and they provide insight into emerging technologies for physicians, administrators, and other interested groups. Chapters address key topics in current literature with regard to the generation, transfer, interpretation, and distribution of images.

This new edition has been updated to include: 1. An overview of the latest medical imaging standards; 2. A discussion of security issues as they relate to PACS, especially regarding HIPAA; 3. An introduction to current information on PACS workstations, including the impact of new software and hardware on radiologists; 4. An updated explanation of data storage and compression that highlights how advancements are applied; 5. A section on how PACS influences research and education.

Computational methodologies of signal processing and imaging analysis, namely considering 2D and 3D images, are commonly used in different applications of the human society. For example, Computational Vision systems are progressively used for surveillance tasks, traf?c analysis, recognition process, inspection p- poses, human-machine interfaces, 3D vision and deformation analysis. One of the main characteristics of the Computational Vision domain is its int- multidisciplinary. In fact, in this domain, methodologies of several more fundam- tal sciences, such as Informatics, Mathematics, Statistics, Psychology, Mechanics and Physics are usually used. Besides this inter-multidisciplinary characteristic, one of the main reasons that contributes for the continually effort done in this domain of the human knowledge is the number of applications in the medical area. For instance, it is possible to consider the use of statistical or physical procedures on medical images in order to model the represented structures. This modeling can have different goals, for example: shape reconstruction, segmentation, registration, behavior interpretation and simulation, motion and deformation analysis, virtual reality, computer-assisted therapy or tissue characterization. The main objective of the ECCOMAS Thematic Conferences on Computational Vision and Medical Image Processing (VIPimage) is to promote a comprehensive forum for discussion on the recent advances in the related ?elds trying to id- tify widespread areas of potential collaboration between researchers of different sciences.

There is an enormous sense of excitement in the communities of cancer research and cancer care as we move into the middle third of the ?rst decade of the 21st century. For the ?rst time, there is a true sense of c- ?dence that the tools provided by the human genome project will enable cancer researchers to crack the code of genomic abnormalities that allow tumor cells to live within the body and provide highly speci?c, virtually non-toxic therapies for the eradication, or at least ?rm control of human cancers. There is also good reason to hope that these same lines of inquiry will yield better tests for screening, early detection, and prev- tion of progression beyond curability. While these developments provide a legitimate basis for much op- mism, many patients will continue to develop cancers and suffer from their debilitating effects, even as research moves ahead. For these in- viduals, it is imperative that the cancer ?eld make the best possible use of the tools available to provide present day cancer patients with the best chances for cure, effective palliation, or, at the very least, relief from symptoms caused by acute intercurrent complications of cancer. A modality that has emerged as a very useful approach to at least some of these goals is tumor ablation by the use of physical or physiochemical approache

Radiation safety and risk management, a critical issue in the nuclear age, is an ongoing concern in the field of radiation health risk sciences. It is the particular mission and task of the Nagasaki University Global COE program to explore human health risks from radiation on a global scale and to come up with measures for overcoming its negative legacies. Ionizing radiation is a well-documented human cancer risk factor, and long-term health consequences in individuals exposed at a young age to such events as the Hiroshima and Nagasaki atomic bombing are now being followed up. Unique and comprehensive, this book introduces updated radiation health-related issues, including the proper collection and analysis of biological samples, cancer research, psychological effects, fair disclosure, and the effects of low-dose exposure as they apply to future public health policy. Also addressed is the need for emergency radiation medicine in case of accidents.

Authored by leading international researchers, this monograph introduces and reviews developed tomograhic methods for discovering 2D and 3D structures of the ionosphere, and discusses the experimental implementation of these methods. The detailed derivations and explanations make this book an excellent starting point for non-specialists.

This work has true international scope, being a unique European/American joint venture that focuses on the state of the art in both diagnostic and therapeutic radionuclide methodology. Pertinent clinical applications are emphasized rather than attempting to cover everything included in the several large comprehensive texts available in our field. This "practical" approach should make it an essential guide to nuclear medicine physicians, technologists, students and interested clinicians alike.

Medical Management of Heart Failure brings together the current knowledge on the medical management of heart failure into one cohesive volume. It includes copious illustrations and photographic material that will explain the techniques and medical management of patients with heart failure in an effective modern format.

This lavishly illustrated unique atlas provides a comprehensive and up-to-date overview of FAF imaging in retinal diseases. It also compares FAF findings with other imaging techniques such as fundus photograph, fluorescein- and ICG angiography as well as optical coherence tomography.

General ophthalmologists as well as retina specialists will find this a very useful guide which illustrates typical FAF characteristics of various retinal diseases.

Plain radiography is still alive. In many institutions, including ours, conventional radiography has been replaced by digital systems including imaging-plate-based computed radiography and fat-panel detector-based digital radiography. Even for the education of radiation technologists, conventional flm-screen radiography has been de-- phasized, and their education is concentrated on digital systems. Spatial resolution of a conventional system is still far better than the current digital systems, although the dynamic range is wider in the latter system. Industrial flm radiography with small grain size and direct exposure has an even higher resolution, and such hi- resolution systems are something we lost in the transition from the conventional system to the current PACS-friendly system. I am pleased to know that Giuseppe Guglielmi and Wilfred Peh have published this textbook of high-resolution hand radiographs that cannot be obtained with any other techniques. Radiography has always been the most important modality in the evaluation of the hand, and, moreover, high-resolution industrial flms are extremely efective in the evaluation of the hand, particularly for assessing subtle erosions. Hands are not just one of the peripheries of the human body. Tey refect conditions of the whole human body. Not only the metabolic status, but also many congenital disorders are manifested in the hand. Radiographic fndings of the hand are ofen specifc, and contribute to the diagnoses a great deal. Tere have been several publications concerning the radiology of the hand, and they have been well accepted.

Covering the entire spectrum of this fast-changing field, Diagnostic Imaging: Oncology, second edition, is an invaluable resource for radiologists and surgical and medical oncologists-anyone who requires an easily accessible, highly visual reference covering cancer imaging and staging. A team of renowned experts in radiology, oncology, and body imaging provide carefully updated information and an abundance of high-quality images throughout, making this edition a useful learning tool as well as a handy reference for daily practice. Features nearly 3,000 annotated images, including lavish, full-color graphics for each cancer stage and many new illustrations throughout Brings you up to speed with updated TNM and grading tables from the new American Joint Committee on Cancer (AJCC) Cancer Staging Manual and updated WHO classifications Includes new chapters covering radiological staging of tumors recently introduced in the AJCC 8th edition and new chapter divisions that reflect the current AJCC staging system Provides practical, easy-to-find details on routes of spread, imaging techniques, suggestions for treatment based on tumor stages identified in a patient's imaging studies, and extensive imaging examples of a variety of cancers in many different stages Begins each chapter with updated TNM staging tables from the AJCC followed by full-color graphic depictions of TNM criteria Uses bulleted, succinct text for quick comprehension of essential information, as well as a consistent chapter format offering an Overview, Relevant Pathology, Imaging Findings, Clinical Issues, Reporting Checklist, and Selected References Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices

This is the first book to cover minimal-invasive treatment of osteoporotic, tumorous and traumatic vertebral fractures in the English language. In addition to detailed descriptions of the techniques, including tips and tricks from experts, the book contains a chapter about the medical treatment of osteoporosis, which is indispensable in the interdisciplinary approach to osteoporosis. This acclaimed innovative concept unites several treatment aspects. More conservative treatment methods are also presented in this work.

All chapters reflect new developments and clinical findings in the field of orthopaedics, surgery, traumatology and neurosurgery.

This is an atlas on contemporary MR imaging of the reer in neuroradiology she has continuously gathered pediatric central nervous system. We have concen- interesting cases. When Dr. Ketonen moved from trated on brain imaging,but have an extensive chap- Massachusetts General Hospital in Boston to the U- ter on the spine and a smaller chapter on the head versity of Rochester it was quite obvious,looking into and neck. her new of?ce, that she had a very extensive collec- The book starts with a chapter on the normal tion of such cases. She would have needed a much myelinization and normal variance. We are including larger of?ce than the one we were able to offer her chapters on malformations,inherited conditions,in- just to store her enormous teaching ?le. Seeing her fection,tumors,trauma,vascular abnormalities,and phenomenal collection of cases and pairing that with spine abnormalities. The last chapter of the book is a our positive experience writing our previous book, miscellaneous chapter that includes all those cases Diffusion-Weighted MR Imaging of the Brain, it was that did not ?t well in other categories. The chapter obvious that we had both an idea and the material for on trauma and brain damage includes an extensive another neuro-imaging book. We decided on the t- section on CNS manifestations of nonaccidental pe- ic of pediatric neuro-imaging with Dr. Ketonen as the diatric trauma. There is an also an exciting chapter lead author.

The sober explanation for this book is a call by the Springer-Verlag, London, to edit a publication on 'The functional relevance of the collateral circulation' of the heart. Alternatively, it could be 'sold' as the result of my intention to reduce entropy of 18 years of scientific work on the topic of the coronary circulation, which was itself meant to diminish the amount of 'useless' energy. Such a process of reducing disarray in a system with the aim of grasping it better is related to simplification, which carries the risk of introducing error. This can be exemplified by the historic view of angina pectoris, which used to be simplified as being always fatal, thus obscuring for nearly two centuries the view of a 'self-healing' mechanism such as the collateral circulation of the heart. It would be na?]ve, to assume the present work to be free of erroneous oversimplification, because the very nature of scientific work is related to generating (simple) hypotheses with their subsequent falsification. In that context and bluntly, my primary interest in the field of the collateral circulation was not initiated with a vision of eradicating the consequences of coronary artery disease (CAD) by promoting the growth of natural bypasses. The time for such sizeable ideas had passed in the 1970s with the start of the work by Wolfgang Schaper."

Endovascular Neurosurgery represents a unique collaboration between contributors from a number of specialties, all of whom are concerned with the management of cerebrovascular disease. This provides a balanced account of the efficacy of interventional endovascular techniques in this group of conditions. As a result, Endovascular Neurosurgery will prove an invaluable account of a relatively new specialty and will be essential reading for neurosurgeons, neurologists, neuroradiologists, neurophysiologists and neuroanaesthetists.

Covers the whole range of potential complications of PCI

Only book exclusively dedicated to the risks of PCI

Complements available texts that detail interventional cardiology

Supports physicians in improving care by anticipating or recognizing problems

Appeals to cardiologists or interventional radiologists

Addresses cardiac arrest, legal matters and adverse event reporting

Essential information is easily accessible in useful tables

Text is logically organized and richly illustrated with 184 illustrations on 210 pages

Functional magnetic resonance imaging (fMRI) measures quick, tiny metabolic changes that take place in the brain, providing the most sensitive method currently available for identifying, investigating, and monitoring brain tumors, stroke, and chronic disorders of the nervous system like multiple sclerosis, and brain abnormalities related to dementia or seizures. This overview explains the principles of fMRI, scanning methodlogies, experimental design and data analysis, and outlines challenges and limitations of fMRI. It also provides a detailed neuroanatomic atlas, and describes clinical applications of fMRI in cognitive, sensory, and motor cases, translating research into clinical application.

This volume provides a comprehensive account of the use of MRI and CT cross-sectional imaging techniques to identify and characterize developmental anomalies and acquired diseases of the female genital tract. Benign and malignant diseases are considered, and attention is also paid to normal anatomical findings and variants. Emphasis is on the most recent diagnostic and technical advances, and the text is complemented by detailed illustrations.

This easy-to-use, clinically oriented learning guide presents 115 unique cases that cover the scope of cardiac imaging, including congenital, ischemic, myocardial, valvular, and pericardial heart disease, as well as postintervention complications. Given the standard format of problem and solution, each case is structured for effective review and learning for both the resident-in-training and the experienced clinician. Cases are categorized by section: the first encompasses a brief review of basic anatomy, and subsequent sections are divided by disease category. Featuring over 440 images and accompanied by brief yet informative discussions, Cardiac Imaging Cases is the ideal resource and reference guide for anyone in the field of cardiovascular radiology. Also available as an app for iPad on the Apple iTunes store.

With every chapter revised and updated, Physics for Diagnostic Radiology, Third Edition continues to emphasise the importance of physics education as a critical component of radiology training. This bestselling text helps readers understand how various imaging techniques work, from planar analogue and digital radiology to computed tomography (CT), nuclear medicine, and positron emission tomography (PET) to ultrasound imaging and magnetic resonance imaging (MRI).

New to the Third Edition

• Material on digital receptors
• Emphasis on the differences between analogue and digital images
• Coverage of multi-slice CT and three-dimensional resolution, dual energy applications, and cone beam CT
• Special radiographic techniques, including subtraction techniques and interventional radiology
• New chapter on PET, with discussion of multi-modality imaging (PET/CT)
• Additional material on radiation doses and risks to patients
• New chapter covering picture archiving and communication system (PACS), teleradiology, networks, archiving, and related factors
• A summary of the main teaching points at the beginning of each chapter

After an introductory chapter on basic physics, the book follows the x-ray imaging process: production of x-rays, interaction with the patient, radiation measurement, the image receptor, the radiological image, and image quality assessment. It then covers more advanced x-ray techniques as well as imaging with radioactive materials. The text also focuses on radiobiology, risk and radiation protection, and imaging with non-ionising radiation. The final chapter discusses data handling in a modern, electronic radiology department.

From the time questions about the impact of wireless technology on public health were first raised in 1993 through the present, Wireless Technology Research, LLC (WTR) has been the largest independent surveillance and research program trying to identify and solve human health problems associated with wireless phones. In 1995 at the University "La Sapienza" of Rome, WTR sponsored the first comprehensive forum for the discussion of these issues. Papers from the 1995 State of the Science Colloquium were collected andpublished in Volume I ofthis series, Wireless Phones andHealth: Scientific Progress. This second volume assembles papers presented at WTR's Second State of the Science Colloquium in Long Beach, CA, in June 1999; it contains the most comprehensive research on the public health impact of wireless phones to date. The operating words for the proper understanding of these data are science and public health. Science is a tool for making public health decisions, but the framework in which we are operating is truly that of public health. We are looking for problems that have to do with wireless technology. We are trying to decide how this technology impacts on the public for one purpose and one purpose alone, and that purpose is to solve problems that are identified. I would like to challenge you, the reader, to suspend your parochial orientation as you consider these latest findings.

Over the past several decades, much progress has been made in understanding the mechanisms of electrical activity in biological tissues and systems, and for developing non-invasive functional imaging technologies to aid clinical diagnosis of dysfunction in the human body. The book will provide full basic coverage of the fundamentals of modeling of electrical activity in various human organs, such as heart and brain. It will include details of bioelectromagnetic measurements and source imaging technologies, as well as biomedical applications. The book will review the latest trends in the field and comment on the future direction in this fast developing line of research.

Covering both noninvasive and surgical treatment alternatives, Critical Limb Ischemia defines practical guidelines for a multidisciplinary approach to critical limb ischemia and follows a step-by-step description of the latest techniques. Topics covered include: Balloon angioplasty and stenting Cryoplasty Pharmacotherapy Topical therapies combined with hyperbolic oxygen treatment Endovascular techniques Strategies for leg revascularization The book provides vascular surgeons, general and interventional cardiologists, interventionalists, radiologists, podiatrists, and endocrinologists a valuable resource for daily practice.

Automatic image analysis has become an important tool in many fields of biology, medicine, and other sciences. Since the first edition of Image Analysis: Methods and Applications, the development of both software and hardware technology has undergone quantum leaps. For example, specific mathematical filters have been developed for quality enhancement of original images and for extraction of specific features of interest. Also, more complex programs have been developed for the analysis of object forms in distinguishing cancer cells from normal tissue cells. Just as significant, three-dimensional analysis of proteins, organelles, or macroscopic objects is even more complex. In addition, recent space-based experiments have optimized techniques for the extraction of movement parameters of numerous motile objects. The second edition of Image Analysis: Methods and Applications addresses all these new developments. Moreover, two new chapters have been added. One focuses on images on the internet, and the other discusses microscope image restoration. These chapters add significantly to the existing body of information on Internet communication protocol and environment as well as to that on image file formats considerations. The materials also include a list of internet Web sites that pertain to digital images and software along with those that relate to image processing. With these considerations in mind, Image Analysis: Methods and Application, Second Edition is of incalculable value to professionals, academics, and users of all aspects of image analysis in biology and other areas of science.