As an addition to the European postgraduate training system for young neurosurgeons we began to publish in 1974 this series devoted to Advances and Technical Standards in Neurosurgery which was later sponsored by the European Association of Neurosurgical Societies. The fact that the English language is well on the way to becoming the international medium at European scientific conferences is a great asset in terms of mutual understanding. Therefore we have decided to publish all contributions in English, regardless of the native language of the authors. All contributions are submitted to the entire editorial board before publication of any volume. Our series is not intended to compete with the publications of original scientific papers in other neurosurgical journals. Our intention is, rather, to present fields of neurosurgery and related areas in which important recent advances have been made. The contributions are written by specialists in the given fields and constitute the first part of each volume. In the second part of each volume, we publish detailed descriptions Of standard operative procedures, furnished by experienced clinicians; in these articles the authors describe the techniques they employ and explain the advantages, difficulties and risks involved in the various procedures. This part is intended primarily to assist young neurosurgeons in their post graduate training. However, we are convinced that it will also be useful to experienced, fully trained neurosurgeons."

2 Diagnostic Use of Radiographic Methods in Coronary Disease. . . . . . . . . . . . . . . . . . . . . . . . . . 56 3 Material. . . . . . . . . . . . . . . . . . . . . . . . . 58 4 Mode of Operation . . . . . . . . . . . . . 62 5 Radiological Projections. . . . . . . . . . . . . . . . . 63 6 Monitoring of Cardiac Parameters . . . . . . . . . . . . 64 7 Pharmacological Tests . . . . . . . . . . . . . . . . 66 7. 1 Coronary Arteries . . . . . . . . . . . . . . . . . . . . . 66 7. 2 Left Ventricle. . . . . . . . . . . . . . . . . . . . . . . . 67 8 Accidents and Risks of Coronary Arteriography . . . . . 67 References . . . . . . . . . . . . . . . . . . . . . . . . . 68 III Angiographic Explorations: Normal Results . . . 71 1 Left Ventricle and Left Ventricular Function 71 1. 1 Radiological Anatomy. . . . . . . . . . . . 71 1. 2 Normal Kinetics. . . . . . . . . . . . . . . 77 1. 3 Analysis of Wall Contraction . . . . . . 78 1. 4 Volumes and Function Indexes. . . . . . . 81 2 Coronary Arteries and Veins . . . . . . . . 84 2. 1 Origin, Calibre and Preponderance of the Coronary Arteries . . . . . . . . . . . . . . . . . . . . . . . . 84 2. 2 Nomenclature and Segmentation of the Coronary Arteries . . . . . . . . . . . . . . . . . . . . . . 87 2. 3 A Reminder About the Physiology of Coronary Circulation . . . . . . . . . . . 93 2. 4 Angiographic Anatomy . . . . . . . . . . 94 2. 4. 1 Left Coronary Artery . . . . . . . . . . . 94 2. 4. 2 Right Coronary Artery. . . . . . . . . . . . . 95 2. 4. 3 Vascularization of Nodes and the Conduction System . . 96 2. 4. 4 Interconnecting Anastomoses . . . . . . . . . . . . . . . 97 2. 5 Coronary Veins . . . . . . . . . . . . . . . . . . . 97 References . . . . . . . . . . . . . . . . . . . . . . . . . 98 IV Angiographic Explorations: Congenital Anomalies of the Coronary Arteries. . . . . . . . . . . . . . . . . . . . . . . . 100 1 Anomalies of the Origin, Course and Distribution of Coronary Arteries Arising from the Aorta . . . . . . . . 100 2 Abnormal Origin of a Coronary Artery from the Pulmonary Artery . . . . . . . . . . . . . . . . . . . . . 101 3 Anomalies in the Diameter of Coronary Arteries . . . . . 104 4 Coronary Fistulae . . . . . . . . . . . 109 References . . . . . . . . . . . . . . . . . . . . . . . . . 113 VII V Angiographic Explorations: Coronary Atheroma. . . . . . . . 114 1 Left Ventricle . . . . . . . . . . . . . . . . . . . . . . . . 114 1. 1 Morphological Anomalies: Bulging and Lacuna-Like Aspects . . . . . . . . . . . . . . . . . . . . . . . . . . .

The concept of the ISS was developed in 1972 by three Internationally renowned radio logists; Harold G. Jacobson M. D. , Ronald O. Murray M. D. , and Jack Edeiken M. D. Their hard work and dedication allowed their vision to become a reality when the first meeting of the Society was held in 1974. The ISS is an interdisciplinary society dedicated to the learning, understanding, and teaching of musculoskeletal disorders. From the beginning, the Society established itself as a premier society, and its members, all experts in their respective fields, continue to make significant contributions to the field of medicine. The sharing of knowledge and a feeling of camaraderie by the members has made this truly a unique society. The Book of Members is in part a historical compilation of information about the Society. The first edition was compiled by Friedrich W. Heuck, Dr. med. , and spanned the first fifteen years of the Society. Dr. Heuck's contribution to the first edition is immeasurable". In the book, Harold Jacobson M. D. presented his historical perspective of the beginnings of the Society and Dr. Heuck presented information of the years that followed. I have brought that information up to date in this edition, and have added new facts about the Society and its membership. The amount of information about each member of the Society is purposefully less than that which was presented in the first edition, as the Society has grown to 427 members and 20 Honorary members .

Percutaneous transluminal angioscopy is opening up exciting possibilities for the interventional radiologist, since it can picture vascular features with an accuracy and clarity that previously has not been possible. Dr. Beck paves the way for the use of this new tool in clinical diagnosis; he details the technical prerequisites, gives step-by-step instructions for applying the technique and discusses how to interprete the resulting images. The amazing results of percutaneous angioscopy are compared with the results of conventional angioscopy. This approach introduces the new and unknown in perspective with the tried and trusted of the past. Major advantages become obvious: unclear or uncertain angiographical findings can be cleared up, interventional procedures can be supported, and the effects of interventional radiology can be seen before and after vascular treatment. The author's unique insight and systematic approach to the vascular system make this atlas a truly pioneering work.

Master of all endocrine activity and executive organ of one's quality of life, the pituitary gland is tightly lodged in the" turkish saddle. " As a bony container, the sella turcica is to the hypophysis what the skull is to the brain; it can therefore be looked upon as a little vault within the cranial vault. Just as the cranium is moulded by the growth of the brain, so is the sella fashioned by its content. It becomes locally enlarged in response to expanding intrasellar lesions, and it tends to return to its original size and shape upon their removal or destruction. Pituitary adenomas have in the past been diagnosed upon enlargement of the sella turcica. In the past decade, as a direct result of interdisciplinary coopera- tion, we have learned that tiny adenomas, the immediate cause of some cases of acromegaly, amenorrhea-galactorrhea syndrome, or Cushing's disease, can exist with minimal or no observable effect on the size of the sella. The break- through started when radioimmunoassay, as a new method of accurately measur- ing specific hormonal output, indicated selective pituitary oversecretions in pa- tients with normal-sized sellae. Neurosurgeons highly skilled in the transsphenoi- dal approach with the surgical microscope were obliged to operate on some of these patients and confirmed the presence of tiny oversecreting adenomas in their pituitary glands.

The quantitative analysis of blood flow within central and peripheral blood vessels has attracted more and more interest, for with the rapid developments in vascular surgery and the introduction of percutaneous transluminal angioplasty, it is becom ing increasingly important to be able to measure regional blood flow in man. In clinical radiology, angiography has been used predominantly from the point of view of its morphological applications. However, theoretically angiography may also be regarded as a specific application of indicator-dilution measurements of blood flow. The indicator is contrast medium (CM), the changing concentration of which is re corded by cinematography or video-electronic systems at sites downstream from the point of injection. The curves of density thus obtained correspond to indicator-di lution curves. The blood flow can be calculated from the concentration-time curves ofCM in much the same way as it is estimated from other indicator-dilution curves. In our early work with clinical application of videodensitometric measurement of blood flow in the iliac artery, we found that this method did not offer as high a degree of accuracy as one would have expected from investigations by other authors. We saw that we needed to examine the following problems: 1. We had to investigate whether our conventional X-ray equipment and video densitometer could be viewed as a linear measuring system. To what extent do unavoidable nonlinear changes in the measuring signals influence the blood flow values? 2."

The anatomic structure of the vascular supply of the pelvis has long been the subject of study. Progress in angiography rendered it a valu- able diagnostic aid. Nevertheless, angiography is finding new applica- tions in combination with the technique of superselective catheteriza- tion, opening the way for interventional angiography. Remarkable as this may prove, one must not overlook the difficulties involved, most of which essentially result from insufficient knowledge of the anatomic structure concerned: the pelvic arteries are particularly pro b- lema tic owing to their complexity and multiple variations. For this reason we here attempt to chart precisely the course of each artery supplying the pelvis and to provide a synthetic study of the different vascular territories. The book is completed by some pathologic exam- ples which illustrate the sometimes very important role of embolization in therapy. VII Acknowledgements This work has been produced in close collaboration with urologists, gynecologists, orthopedic surgeons, gastroitestinal surgeons, and neu- rosurgeons. We would particularly like to thank all those who have referred their patients to us, and especially Prof. Kuss from the Depart- ment of Urology, Hopital La Pitie, whose role in the realization of this book was crucial, and his colleagues, Prof. LE GUILLOU, Prof. JARDIN, and Prof. CHATELAIN. Others to whom we owe our thanks in the above respect are Prof. STEG and Prof. BoccoN-GmoD (Depart- ment of Urology, Hopital Cochin); Prof. DUFOUR, Prof. CUKIER, and Dr. LEPAGE (Department of Urology, Hopital Necker); Prof.

The cerebello-pontine angle has always posed a challenge to the neurosurgeon, the otoneurosurgeon, and the neuroradiologist. Angle masses which are very small and difficult to detect frequently produce symptoms, but may remain silent while growing to exceptional size. The neuroradiologist must have firm knowl edge of the clinical manifestations of the diverse angle lesions in order to tailor his studies to the patients' needs. The majority of angle lesions are benign; thus successful surgery has the potential for complete cure. Angle lesions typically arise in conjunction with vital neurovascular structures, and often displace these away from their expected positions. Large lesions may attenuate the vestibulocochlear and facial nerves and thin them over their dome. Since the nerves often remain functional, the surgeon then faces the need to separate the tumor from the contiguous nerve, with preservation of neurological function. Depending on the exact location and extension of the lesion, resection may best be attempted via otologic or neurosurgical approaches. The neuroradiologist must determine - precisely -the presence, site, size, and extension( s) of the lesion and the displacement of vital neurovascular structures as a guide to selecting the line of surgical attack. Since the arteries, veins, and nerves that traverse the angle are fine structures, the neuroradiologist must perform studies of the highest quality to do his job effectively."

During the past few years, a considerable number of monographs on bone tumors have been published. They are mainly restricted to bone tumors as clinical-pathological entities, since their diagnosis, more than that of other tumors, requires the interdisciplinary cooperation between orthopedic specialist, radiologist, and pathologist. However, investiga tions concerning the histogenesis of bone tumors are rather limited, although they might be helpful in explaining the unique morphological heterogeneity of tumors of the skeletal system. Furthermore, the histo genetic approach in the study of bone tumors may facilitate the inter pretation of the advanced cytobiological methods available for improv ing classification and diagnosis. Therefore, this volume presents recent pathological advances in the biological characterization of bone tumors. A major chapter deals with the differential diagnosis of Ewing's sarcoma as regards its demarcation from the so-called neuroectodermal tumor of bone. The analysis of the ground substances in bone-forming tumors may be helpful for their classification. Therefore the volume includes a chapter on the biochemical and histochemical analysis of different osteosarcoma types. Recently it has become clear that in addition to different collagen types which are not specific for bone tissue, several bone-specific proteins occur, one of which is osteonectin. Its distribu tion is obviously important for the classification and diagnosis of osteo blastic tumors. Proliferative behavior is of major importance for the diagnosis of malignant tumors.

This book has been written for radiologists, ophthalmologists, neurologists, neurosur geons, plastic surgeons, and others interested in the evaluation of disorders with ophthalmologic signs and symptoms. It is designed to provide recent knowledge in this area derived from ultrasonography, computed tomography (CT), and magnetic resonance imaging (MRI). In the past decade, the advent of ultrasonography, computed tomography, and more recently magnetic resonance imaging has provided diagnostic images of the eye, orbit, and brain in a fashion that had been a dream of many prior to the develop ment of these techniques. These newer modes of diagnosis have replaced some previous techniques, such as nuclear medicine imaging and, to some degree, vascular studies and orbitography. There are three sections to this book. The first section is a discussion of the imaging techniques. The second is devoted to the role of these imaging methods in the evaluation of ophthalmic disorders. The last section, dealing with radiotherapy for ophthalmologic tumors, is included because the current imaging techniques are needed for treatment planning. We wish to thank the many people who have assisted us in preparing this manuscript. Among these are many librarians, secretaries, trainees, and photographers. Weare especially indebted to artist Peter Clark for his illustrations and to Mr. Martin Leibo vici, Associate Curator of New York University Medical School and Director of Health Sciences Library of Goldwater Memorial Hospital, New York City. Also, we wish to thank our families for their help and patience."

The management of ankle injuries has long been a stumbling block for orthopae dists in training. As a first year resident, I was fortunate to encounter the series of articles by N. Lauge-Hansen and T. Baek Kristensen that classified ankle injuries according to their mechanism. I found this information quite helpful throughout my residency and early years of practice. Several years ago, an attempt was made to summarize this material for the benefit of the orthopaedic house staff of Thomas Jefferson University. It quickly become obvious that such a "manual" would require a great deal of professional illustration and editorial assistance in order to be effective. Almost simulta neously, a fortuitous encounter with Ms. Marie Low (at that time Medical Editor of Springer-Verlag New York Incorporated) provided both the stimulus and the means to present this information in the manner and detail which it deserved. Contributors were carefully selected for their knowledge and experience in particular areas and for their willingness to cooperate in providing a smooth flowing manuscript. This text contains little new material. Rather, it represents an attempt to bring together, under one cover, the wealth of extant information on this subject. Wherever a consensus could not be perceived, conflicting views have been sum marized as objectively as possible. Unfortunately, there are still many aspects of ankle injury for which we have more questions than answers."

As an addition to the European postgraduate training system for young neurosurgeons we began to publish in 1974 this series devoted to Advances and Technical Standards in Neurosurgery which was later sponsored by the European Association of Neurosurgical Societies. The fact that the English language is well on the way to becoming the international medium at European scientific conferences is a great asset in terms of mutual understanding. Therefore we have decided to publish all contributions in English, regardless of the native language of the authors. All contributions are submitted to the entire editorial board before publication of any volume. Our series is not intended to compete with the puhlicationR of original scientific papers in other neurosurgical journals. Our intention is, rather, to present fields of neurosurgery and related areas in which important recent advances have been made. The contributions are written by specialists in the given fields and constitute the first part of each volume. In the second part of each volume, we publish detailed descriptions of standard operative procedures, furnished by experienced clinicians; in these articles the authors describe the techniques they employ and explain the advantages, difficulties and risks involved in the various procedures. This part is intended primarily to assist young neurosurgeons in their postgraduate training. However, we are convinced that it will also be useful to experienced, fully trained neurosurgeons.

When I planned this book seven years ago I had my graduate students at the University of Ulm in mind, diploma as well as doctoral students, who often asked me what literature they should work with. I used to suggest a list of ten to twenty (for my taste: excellent) treatises on NMR. Apparently this did not make them entirely happy. The difficulty which newcomers to the field face is to practise and to apply theoretical formalisms from different sources while still learning the principles of NMR and being actively engaged in NMR research. Although the text presented here is largely based on my lecture notes, the result is a "working book" rather than an introduction. It is intended to provide direct access to the basic information one needs for NMR diffusometry, relaxometry, and tomography applications. A "working book" is certainly not suitable to be read starting on page one and then carrying on until the last page. Boldly extrapolating my own reading habits to those of the typical scientist I am sure that this is not the way in which monographs of this kind are read nowadays. So my aim was to produce a treatise that offers easy and quick access for the reader to relevant matters of interest. I tried hard to ease the comprehension of NMR principles by extensive cross-referencing among the sections and chapters. Tomography, diffusometry and relaxometry are fields based on common phys ical principles."

This book constitutes the refereed proceedings of the First International Workshop on Multimodal Brain Image Analysis, held in conjunction with MICCAI 2011, in Toronto, Canada, in September 2011.
The 15 revised full papers presented together with 4 poster papers were carefully reviewed and selected from 24 submissions. The objective of this workshop is to facilitate advancements in the multimodal brain image analysis field, in terms of analysis methodologies, algorithms, software systems, validation approaches, benchmark datasets, neuroscience, and clinical applications.

As an addition to the European postgraduate training system for young neurosurgeons we began to publish in 1974 this series devoted to Advances and Technical Standards in Neurosurgery which was later sponsored by the Euro pean Association of Neurosurgical Societies. The fact that the English language is well on the way to becoming the international medium at European scientific conferences is a great asset in terms of mutual understanding. Therefore we have decided to publish all contributions in English, regardless of the native language of the authors. All contributions are submitted to the entire editorial board before publication of any volume. Our series is not intended to compete with the publications of original scientific papers in other neurosurgical journals. Our intention is, rather, to present fields of neurosurgery and related areas in which important recent advances have been made. The contributions are written by specialists in the given fields and constitute the first part of each volume. In the second part of each volume, we publish detailed descriptions of standard operative procedures, furnished by experienced clinicians; in these articles the authors describe the techniques they employ and explain the advantages, difficulties and risks involved in the various procedures. This part is intended primarily to assist young neurosurgeons in their postgraduate training. However, we are convinced that it will also be useful to experienced, fully trained neurosurgeons."

In the last few years ways of thinking in psychiatry have undergone considerable change thanks to advances in the fields of morphology and plasticity of the CNS, particularly with regard to schizophrenic and mood disorders. In addition, the rapid and considerable development of neuroimaging techniques (CT, MRI, PET and computerized EEG) and of molecular genetics (through DNA recombinant meth odologies) have widened the approach to these disorders in a way unimagined a few years ago. These advances and the new etiopathogenetic hypotheses that have sprung from them were the central theme of the Second International Meeting on Schizophre nia "Morphology and Plasticity of the Central Nervous System - A Challenge for Psychiatry of the Nineties" which was organized by the Association for Research on Schizophrenia (ARS), the Schizophrenia Research Center of the Institute of Psychiatry of the University of Milan and the T. and F. Legrenzi Foundation, held in Milan on October 22-24, 1987. This book contains the contributions from participants of the meeting, which took place in a warm and friendly atmosphere and marked by lively and exhaustive discussions on the various papers. The contributions were recently revised for the present publication. We would like to express our appreciation to the book's contributors for the high quality of their reports."

Trauma to the abdomen, both accidental and willful, has become increasingly common in this era of increasing violence. Large numbers of patients all over the country are admitted to emergency rooms because of abdominal trauma of varying degrees of severity. All too often the correct diagnosis is suspected belatedly or not at all, so that proper treatment is not initiated in sufficient time to be lifesaving. Not infre quently, the injured patient is examined by an intern or an insufficiently experienced resident physician. Even in instances where more senior internists and surgeons are available, detailed knowledge about the necessary methodology to establish the correct diagnosis and institute the appropriate treatment is lacking. This monograph, representing the felicitous collaboration of a surgeon and a radiolo gist together with several other contributors, is timely and important. The authors (and their contributors) have approached their subject with a wealth of clinical experi ence obtained in several very active acute-care municipal hospitals in the largest city in this country. They have observed and treated a very large number of patients with a multitude of traumatic causes, including firearm injuries, stab wounds, vehicular accidents, falls, and assaults. The authors have divided this work into four main sections: General Perspectives on Abdominal Injury, Types of Abdominal Injuries, Specific Diagnostic Techniques, and Specific Organ or Supporting-Structure Injury."

There have been significant advances in the treatment of sarcomas in the past several years. Further, different clini cal treatment programs are being advocated in different areas including surgery alone, surgery with preoperative or post operative chemotherapy, surgery with different radiotherapy modalities, with each investigator espousing his own treat ment program. On the other side, there is the question of whether these treatment programs are offering better results or whether the natural history of sarcomas has changed. The International Symposium on Sarcomas was held at Innisbrook Resort, Tarpon Springs, Florida, October 8-10, 1987. This was the first international symposium to date involving all of the disciplines treating sarcomas including pathologists, orthopaedic surgeons, general surgeons, medical oncologists, pediatric oncologists, and radiation oncol ogists. The Symposium brought together a number of special ists working in the clinical field of sarcomas for a presen tation of their specific treatment programs and their results. The presentations were followed by panel discussions to stimulate educational debate as to the different forms of treatment for sarcomas and to formulate some conformity in control of disease, control of spread, and ultimate function for the patient. James R. Ryan, M.D."

Over the past decade, techniques have been developed and implemented to observe metabolism noninvasively in localized regions of intact, living experimental animals and humans through the use of magnetic resonance spectroscopy (MRS). At the same time, magnetic resonance imaging (MRI) techniques developed in the 1970s and refined in this decade have been increasingly applied as a powerful clinical tool to probe human anatomy. Because of the unusual metabolic and physiologic characteristics of malignant tissues, oncology has been one of the primary focuses of the application of both MRS and MRI. Although considerable progress has been made in oncologic applications of magnetic resonance (MR), further research is needed to realize the full potential of MR in this area. Consequently, the 21st Annual Detroit Cancer Symposium entitled "Magnetic Resonance in Experimental and Clin ical Oncology" was organized to provide a forum for researchers in the field to report the state of the art of MRS and MRI in oncol ogy, to discuss future goals for MRS and MRI in oncology, and to define the research needed to meet those goals. The major emphasis of the symposium was on MRS due to both the recent widespread availability of clinical MRS instrumentation and the extensive amount of animal MRS research performed over the past half decade.

Over the past several decades, much progress has been made in understanding the mechanisms of electrical activity in biological tissues and systems, and for developing non-invasive functional imaging technologies to aid clinical diagnosis of dysfunction in the human body. The book will provide full basic coverage of the fundamentals of modeling of electrical activity in various human organs, such as heart and brain. It will include details of bioelectromagnetic measurements and source imaging technologies, as well as biomedical applications. The book will review the latest trends in the field and comment on the future direction in this fast developing line of research.

The importance of osteoporosis in the United Kingdom as a cause of death and disability is now well recognised. There are in excess of 200,000 osteoporotic-related fractures in the UK per annum asso ciated with an estimated cost of GBP942,000,000. Following hip fracture it is known that about 50% of patients are unable to live indepen dently and about 20% of such patients die within the first 6 months. These figures, compelling as they are, reflect poorly on current medical practices which manifestly have failed to identify patients with low bone density at risk of fracture. The hope is that the techni cal advances which have enabled bone mineral density, and other allied indices, to be measured with high precision and accuracy offers the chance of identifying patients at risk of fracture and guiding the clinician to make treatment decisions which may reduce the patients' risk of fracture. In the UK, services for identifying patients at risk of fracture are still in their infancy and are not uniformly available throughout the country. This situation is, however, likely to improve particularly fol lowing the publication of the Royal College of Physicians report "Osteoporosis -clinical guidelines for prevention and treatment" and the recognition in "Our Healthier Nation" that osteoporosis pre vention should be included as a target to achieve a reduction of 20% in accidents by 2010.

Radiophannaceutical research has recently undergone a major change in direction. In past years it has been concerned mainly with the development of perfusion tracers, the biodistribution of which reflect the regional blood flow to areas of major organs such as the heart and brain. However, a major new direction of interest now lies in the development of receptor-binding radio-tracers which can be used to perform in-vivo characterisation of diseased tissues and it is likely that much of the future research in this field will follow this direction. The difficulties in developing such tracers are considerable. The researcher must first identify a promising target for radiopharmaceutical development. High specific activity radioactive molecules must be designed and synthesised which will both bind to the target receptor with high affinity, and also have the physicochemical characteristics which will allow them to reach the target site in sufficient quantity while at the same time showing minimal uptake in non-target tissues. Thus the knowledge base required for radiophannaceutical development has now expanded beyond the limits of radiopharmaceutical chemistry to include aspects of biochemistry, molecular biology and conventional drug design. The portfolio of basic knowledge required to support current radiopharmaceutical development is changing and scientists working in this arena need to be trained in this regard. At the same time, the very latest developments in the field need to be communicated to the scientific community in order to stimulate the advancement of this exciting new direction of research.

This book aims to highlight all the existing information available on first and mid-trimester imaging of palate in prenatal ultrasound and to develop a methodical approach in imaging the palate. As formation of the palate is completed by 11 weeks of gestation and as there are no evolving changes in palatine anatomy at the mid-trimester, diagnosis of palatine clefts can now completely be shifted to late first-trimester. First-trimester evaluation of palate is now gaining importance and a number of techniques have currently been proposed by different authors. This book covers the existing literature and recent 2D and 3D techniques in evaluating palate and helps in the early detection of palatine clefts in the first trimester. Orofacial clefting is one of the most common birth defects and the burden of it in developing countries is substantial. This book helps in improving the counseling options for the obstetrician and the couple early in gestation. It includes 2D and 3D images of various types of palatine clefts and the nuances in imaging the secondary palate extensively. 3D images of the palate also help the multi-disciplinary team especially the maxillofacial surgeons involved in managing orofacial clefts. It also includes videos for easy understanding. This book is a ready reckoner for the imaging specialists and students /trainees involved in prenatal diagnosis. It provides essential information in diagnosing orofacial cleft both to the novice and to the skilled professionals involved in the field of diagnostic fetal ultrasound.

The clinical acceptance of computed anatomic cross-sections. Schematic line tomography (CT) as an integral part of our drawings are also generously used to il diagnostic armamentarium was based on its lustrate particularly complex anatomic re ability to display cross-sectional anatomy gions and help the reader obtain a correct with near anatomic precision. However, perspective on these more difficult regions. the radiologist must first be knowledgeable The book successfully presents a clear per of the complexities of normal anatomy be spective on the anatomy we see daily in fore he can truly make full use of this tech using cross-sectional imaging techniques. nology. This book will prove useful as a learning Michael Farkas has truly made our task guide for the uninitiated, and as a refer as radiologists easier. As noted in the ence for the more experienced. Either preface, the book carefully correlates rep way, it is an important contribution to our resentative CT slices with corresponding literature. Elliot K. Fishman, M.D."

Developments in teleradiology are progressing at great speed. As a consequence, there is a need for a broad overview of the field. This first-ever book on teleradiology is presented in such a way that it should make it accessible to anyone, independent of their knowledge of technology. The text is designed to be used by all professionals, including radiologists, surgeons, nurses and allied health professionals, and computer scientists. In a very short time, driven by technical developments, the field of teleradiology has become too extensive to be covered by only a small number of experts. Therefore, Teleradiology has been written with chapter contributions from a host of renowned international authorities in teleradiology (see the Contents and the Contributors). This ensures that the subject matter focusing on recent advances in teleradiology is truly up to date. Our guiding hope during this task was that as editors of multiple chapters we could still write with a single voice and keep the content coherent and simple. We hope that the clarity of this book makes up for any limitations in its comp- hensiveness.