Basic Clinical Radiobiology is a concise but comprehensive textbook setting out the essentials of the science and clinical application of radiobiology for those seeking accreditation in radiation oncology, clinical radiation physics, and radiation technology.
Fully revised and updated to keep abreast of current developments in radiation biology and radiation oncology, this fifth edition continues to present in an interesting way the biological basis of radiation therapy, discussing the basic principles and significant developments that underlie the latest attempts to improve the radiotherapeutic management of cancer.
This new edition is highly illustrated with attractive 2-colour presentation and now includes new chapters on stem cells, tissue response and the convergence of radiotherapy, radiobiology, and physics. It will be invaluable for FRCR (clinical oncology) and equivalent candidates, SpRs (and equivalent) in radiation oncology, practicing radiation oncologists and radiotherapists, as well as radiobiologists and radiotherapy physicists.

Meningiomas are the most frequently reported neuro-oncologic condition, accounting for 12% to 30% of all primary intracranial tumors. The first case of intracranial meningioma treated with stereotactic radiosurgery was reported by Backlund E-O in 1971. Since then, more than 200,000 meningiomas have been treated with stereotactic radiosurgery worldwide to date. The large number of patients treated using this method is due to the fact that meningiomas are frequently located in critical areas and microsurgery is often associated with severe and permanent neurological complications. This book discusses the advantages, risks and limits of stereotactic radiosurgery relating to all regions of interest for a neuroradiosurgical approach for the treatment of central nervous system meningiomas. Firstly, it presents an introduction focusing on the "state of the art". It then discusses the physics, imaging, neurological and neuro-oncological issues in multidisciplinary management. Lastly, it features a summary of results, including the most recent published papers regarding all the locations involved in the stereotactic radiosurgery treatment as well as new approaches to meningiomas, with particular reference to the hypofrationated treatments. Intended for anyone involved in the neuroradiosurgical treatment of brain diseases, the book provides an up-to-date overview of the latest stereotactic radiosurgery treatment of central nervous system meningiomas.

In this issue of MRI Clinics, guest editor Dr. Ahmed Abdel Khalek Abdel Razek brings his considerable expertise to the topic of MR Imaging of Head and Neck Cancer. Top experts in the field cover key topics such as artificial intelligence and deep learning of head and neck cancer, MR imaging of salivary gland tumors, MR imaging of vascular malformations and tumors of the head and neck, and more. Contains 14 relevant, practice-oriented topics including the role of MR imaging in head and neck squamous cell carcinoma; MR imaging of nasopharyngeal carcinoma; MR imaging of oropharyngeal cancer and oral cavity tumors; MR imaging of laryngeal and hypopharyngeal cancer; MR imaging of nasal and paranasal sinuses tumors; and more. Provides in-depth clinical reviews on MR imaging of head and neck cancer, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Because the liver is a common site of metastatic spread, effective MR imaging of this organ is critically important for patients with cancer as well as those with chronic liver disease. In this issue of MRI Clinics, editors Khaled Elsayes (MD Anderson Cancer Center) and Claude Sirlin (UC San Diego Health's Liver Imaging Group) bring their considerable expertise to the topic of MR Imaging of Chronic Liver Diseases and Liver Cancer. Top experts in the field cover key topics such as artificial intelligence, diffuse liver disease, LI-RADS, and hepatocarcinogenesis. Provides concise and comprehensive coverage of the issues physicians face every day. Presents the latest information on a timely, focused topic under the leadership of experienced editors in the field. Contains 14 relevant, practice-oriented topics including Chronic liver disease; What the hepatologists, oncologists and surgeons want to know from radiologists; CT techniques, protocols, advancements and the future; Errors and misinterpretations in imaging of chronic liver diseases; and more.

This issue of MRI Clinics of North America focuses on MR Safety and is edited by Dr. Robert E. Watson. Articles will include: Key elements of clinical MRI safety; Standardized approaches to MR safety assessment of patients with implanted devices; Performing MRI safely in patients with implanted electronic devices: cardiac electronic implanted devices and neurostimulators; Implanted devices: SAR considerations for common diagnostic examinations; Testing of commonly implanted devices for MR conditional labelling; MR safety in the 7T environment; Physics of MR safety; MRI safety considerations of gadolinium based contrast agents: gadolinium retention and nephrogenic systemic fibrosis; MRI safety: Siting and zoning considerations; Elements of effective patient screening to improve safety in MRI, including use of ferromagnetic detection systems; MRI safety in the interventional environment; MRI Safety: Pregnancy and Lactation; MR safety: Computer MRI simulations for testing of electronic devices; and more!

This book, edited by leading experts in radiology, nuclear medicine, and radiation oncology, offers a wide-ranging, state of the art overview of the specifics and the benefits of a multidisciplinary approach to the use of imaging in image-guided radiation treatments for different tumor types. The entire spectrum of the most important cancers treated by radiation are covered, including CNS, head and neck, lung, breast, gastrointestinal, genitourinary, and gynecological tumors. The opening sections of the book address background issues and a range of important technical aspects. Detailed information is then provided on the use of different imaging techniques for T staging and target volume delineation, response assessment, and follow-up in various parts of the body. The focus of the book ensures that it will be of interest for a multidisciplinary forum of readers comprising radiation oncologists, nuclear medicine physicians, radiologists and other medical professionals.

This issue of MRI Clinics of North America focuses on Advanced MR Techniques for Imaging the Abdomen and Pelvis and is edited by Dr. Sudhakar Venkatesh. Articles will include: Advances in MR Elastography in Liver; Biliary Tract Imaging; Imaging of the Pancreas; PET/MRI Applications in Abdomen and Pelvis; Abbreviated MR Protocols for the Abdomen and Pelvis; Advances in MR Angiography of Abdomen and Pelvis; Advances in MRI of Prostate; Advances in MRI of the Female Pelvis; Advanced MR Techniques for Imaging the Abdomen and Pelvis; Texture Analysis and AI with MR in Abdomen and Pelvis; Advances in MRI of the Kidneys and Upper Urinary Tract, and more!

Learn to avoid and manage complications from non-vascular interventional and interventional oncological procedures The range of non-vascular procedures that can be performed in interventional imaging is vast and includes management of a wide range of conditions, such as treatment of kidney stones, obtaining diagnostic biopsies in suspected cancers, bile duct occlusions, compression fractures, drainage of abscesses, collection of fluids, etc. In particular, various cancers often lend themselves well to local tumor destruction with interventional techniques, while holding morbidity and mortality to a minimum. This compendium presents 45 cases in detail to provide a thorough review of potential complications that may occur during non-vascular interventional radiology and interventional oncological procedures. Each case also includes a list of take-home messages discussing vital prevention strategies for each problem. Key Features: Content presented in case-based format to help the reader benefit from the real-life experiences of the authors and motivate them to take part in identifying the problem and finding a solution to a specific situation Solid coverage of characteristic complications of special technologies, such as thermal ablation and percutaneous CT-guided interstitial high-dose brachytherapy A wealth of information and advice for optimizing patient safety before, during, and after interventional therapy Take-home messages at the end of each case providing vital prevention strategies Complications in Non-vascular Interventional Therapy and Interventional Oncology: Case-based Solutions is an invaluable sourcebook for radiology residents and fellows, experienced interventional radiologists, and all physicians actively performing non-vascular and oncological interventions. This book discusses methods to both avoid and manage complications, thus having the potential to directly enhance patient care. This book includes complimentary access to a digital copy on https://medone.thieme.com.

This book provides a comprehensive and up-to-date overview of major technical advances and research findings in the field of brachytherapy. Especially research conducted on brachytherapy in Japan has made tremendous strides, offering readers valuable insights into new treatment outcomes, evidence and techniques. In the respective chapters, each author elucidates cutting-edge findings, addressing both the basic and clinical aspects including the application to various cancers, and especially focusing on highly valuable data gleaned in Japan. As such, the book will benefit not only radiation oncologists but also basic researchers, radiation technologists, medical physicists and members of medical staff who are involved in the development and utilization of this advanced therapy.

Management of Soft Tissue Sarcoma addresses the diagnosis and best current management of adult soft tissue sarcomas. Edited by world renowned experts, this book delineates and discusses each different sarcoma subtype individually. Both clinical and molecular diagnoses are addressed, and tumor histopathology is employed as the basis of treatment recommendations including surgery, radiation therapy, systemic therapy and novel therapeutics.

Dating Neurological Injury: A Forensic Guide for Radiologists, Other Expert Medical Witnesses, and Attorneys presents a unique way to approach the dating of neurological injury as imaged by modern computed tomography (CT), magnetic resonance (MR) and ultrasound (US). Chapters are presented in a logical progression beginning with the general appearance of normal brain and progressing to the way abnormalities manifest themselves. The emphasis in these discussions is on the appearance of edema and of hemorrhage, as these two findings are the brain's most common response to injury. This volume presents in a systematic fashion the principles involved in the interpretation of images of the central nervous system specifically in a medical-legal setting where concern exists about the occurrence and timing of an injury. Dating Neurological Injury: A Forensic Guide for Radiologists, Other Expert Medical Witnesses, and Attorneys is a welcome addition to institutional, medical, and legal libraries, and to the personal libraries of malpractice defense and plaintiff lawyers and physicians in the neurosciences (neurosurgery, neurology, neuropathology, and neuroradiology) involved in medical-legal issues.

In recent years, great advances in translational research have led to new paradigms in the treatment of cancers of the head and neck. Written by leading international physicians and investigators, this innovative multi-disciplinary book presents the most up-to-date research and clinical approaches. Coverage is given to progress in a variety of clinical settings, including programs of organ and function preservation, curative treatments, unresectable disease, adjuvant treatments in high-risk patients, and recurrent/metastatic disease. Complementary to the techniques of surgery, radiotherapy, and systemic treatments, the authors present data on epidemiology, molecular pathology, normal tissue complications, rehabilitation, palliative care, and treatment in the elderly. State-of-the-art functional imaging is elucidated; and the latest developments in high precision techniques in irradiation, sequencing of chemo- and radiotherapy, as well as the integration of biomolecular therapies into cytotoxic treatments are explored.

This concise but comprehensive textbook sets out the essentials of the science and clinical application of radiobiology for those seeking accreditation in radiation oncology, clinical radiation physics and radiation technology. Fully revised and updated to keep abreast of current developments in radiation biology and radiation oncology, the fourth edition continues to present in an interesting way the biological basis of radiation therapy, discussing the basic principles and significant developments that underlie the latest attempts to improve the radiotherapeutic management of cancer. New topics for the fourth edition include chapters on the mechanisms of cell death, biological response modifiers, and biological image guided radiotherapy, with major revisions to sections on the molecular basis of the radiation response, tumour hypoxia and the dose-rate effect. A variety of new authors have contributed to this revision, who, together with the new Editorial team, have used their significant international teaching experience to ensure the content remains clear and comprehensive, and as valuable to the trainee as it is to the established radiation oncologist. With the fourth edition we will see the most radical change so far - as Professor Gordon Steel has retired as Editor and has been replaced by Bert van der Kogel, the current current course director for the above-mentioned course, plus Michael Joiner, who is the head of the Radiation Biology Program at the Wayne State University and is the Associate Editor of the International Journal of Radiation Biology.

This issue of MRI Clinics of North America focuses on 7T MRI and is edited by Dr. Meng Law. Articles will include: 3T vs 7T MRI: Is It Really Worth It?; High Resolution Structural MRI & Quantitative Susceptibility Mapping; High Resolution Neurovascular Imaging at 7T: Arterial Spin Labeling Perfusion, 4-dimensional MR Angiography and Black blood MRI; 7T and Beyond Functional MRI; Sodium and Other UHF MRI; MR-EYE: Ultra High Field MRI of the Human Eye and Orbit at 7T; 7T MRI of Perivascular Spaces; 7T MRI in "Non Lesional" Epilepsy/ Perivascular Spaces; 7T Multiple Sclerosis; 7T Brain Tumors and Radiation Therapy; 7T Musculoskeletal MRI; Body Applications for 7T; MRI Safety at 7T/Implants; 7T Simultaneous MRI PET with PET Insert; GluCest 7T MRI; and more!

This issue of Radiologic Clinics of North America focuses on Vascular Imaging, and is edited by Dr. Christopher J. Francois. Articles will include: Pre-operative planning for structural heart disease; Updates in vascular CT; Imaging patients with mesenteric ischemia; Imaging patients with pulmonary vascular disease; Peripheral vascular imaging focusing on non-atherosclerotic disease; Imaging thoracic aorta aneurysms; Recent innovations in renal vascular imaging; Radiological imaging in large and medium vessel vasculitis; MR lymphangiography; Recent innovations in vascular ultrasound; Imaging vascular malformations; 4D Flow MRI; and more!

This issue of MRI Clinics of North America focuses on MR Imaging of the Shoulder, and is edited by Drs. Naveen Subhas and Soterios Gyftopoulos. Articles will include: Shoulder MRI & MRA Techniques (New Advances): How I do it; Rotator Cuff Disease (New Concepts and Challenges): How do I read it; The Postoperative Rotator Cuff: How I read it; Anterior Instability: What to look for; Posterior Instability: What to look for; SLAP/biceps/thrower's shoulder: How I read it; Postoperative Labrum and Instability: What to look for; Capsular injury and inflammation: How I read it; AC Joint: What to look for; Nerve and muscle abnormalities: How I read it; Tumor/tumor like lesions: What to look for; Shoulder MRI and US: How do I choose; and more!

In "Avoiding Errors in Radiology: Case-Based Analysis of Causes and PreventiveStrategies," the authors provide 118 real-life examples of interpretation errorsand wrong decisions from both diagnostic and interventional radiology. Ineach case, the authors discuss in detail the context in which the errors weremade, the resulting complications, and strategies for future prevention. Thecases are organized by body region, beginning with the cranium and thenmoving to cases of the breast, chest and abdomen, spinal column, musculoskeletaland vascular systems.

Features: 118 case studies facilitate analysis and discussion of causes of errors and offer preventive strategies to transfer into daily practice 956 high-quality images and explanatory drawings illustrate the cases and pinpoint errors of interpretation and in decision making

"Avoiding Errors in Radiology" is a must-have reference for anyone involved ininterpreting images for diagnosis and in making decisions in interventionalradiology.

In spite of years of clinical research and trials of a variety of new and promising therapies, cancer remains as a major cause of morbidity and mortality. Use of ionizing radiation in treatment of cancer quickly followed the discovery of X-rays and radioactivity at the dawn of the last century. The limited success of radiotherapy has been attributed to several factors if which the intrinsic radioresistance of tumor cells, their fast reproduction, and tumor hypoxia are the major causes.

Radiation Sensitizers: A Contemporary Audit presents data on newer hypoxic cell sensitizers like senazole and deal with old molecules such as chlorpromazine in a new role of sensitization. Bringing together information scattered throughout published and unpublished literature, the book contains contributions from an international panel that examines new therapies and new uses of old therapies. It contains tables and diagrams that illustrate the concepts and make the information easy to find.