Decision Making in Radiation Oncology is a reference book designed to enable radiation oncologists, including those in training, to make diagnostic and treatment decisions effectively and efficiently. The design is based on the belief that "a picture is worth a thousand words." Knowledge is conveyed through an illustrative approach using algorithms, schemas, graphics, and tables. Detailed guidelines are provided for multidisciplinary cancer management and radiation therapy techniques. In addition to the attention-riveting algorithms for diagnosis and treatment, strategies for the management of disease at individual stages are detailed for all the commonly diagnosed malignancies. Clinical trials that have yielded "gold standard" treatment and their results are documented in the schemas. Moreover, radiation techniques, including treatment planning and delivery, are presented in an illustrative way. This groundbreaking publication is an essential tool for physicians in their daily clinical practice.

Gain mastery over the fundamentals of radiation oncology physics! This package gives you over 60 tutorial videos (each 15-20 minutes in length) with a companion text, providing the most complete and effective introduction available. Dr. Ford has tested this approach in formal instruction for years with outstanding results. The text includes extensive problem sets for each chapter. The videos include embedded quizzes and "whiteboard" screen technology to facilitate comprehension. Together, this provides a valuable learning tool both for training purposes and as a refresher for those in practice. Key Features A complete learning package for radiation oncology physics, including a full series of video tutorials with an associated textbook companion website Clearly drawn, simple illustrations throughout the videos and text Embedded quiz feature in the video tutorials for testing comprehension while viewing Each chapter includes problem sets (solutions available to educators)

Die wachsende Sorge urn eine: mnehmende genetische Schadigung der Menschheit durch energiereiche Strahlen fu6t auf Forschungs ergebnissen der Strahlenbiologie, einer Wissenschaft, die zu den Grund lagenfachern der Medizinischen Radiologie gehort. Grenzen und Mog lichkeiten einer modern en radiologischen Krebsbehandlung lassen sich ohne strahlenbiologisches Wissen nicht interpretieren. Forderungen der Strahlenhygiene und des Strahlenschutzes als bestimmende und be grenzende Faktoren fiir den Einsat7 rontgendiagnostischer Verfahren ergeben sich aus der Kenntnis biologischer Effekte der ionisierenden Strahlen. Das Bediirfnis nach sachlicher, pcagnant kurzer Information iiber die Strahlenbiologie und die klinische Nutzung ihrer Erkenntnisse besteht somit nicht nur fiir den Arzt, der sich zum Facharzt fiir Radio logie weiterbildet. 1m Zeitalter der technischen Nutzung der Kern energie und der immer noch nicht gebannten Bedrohung der Mensch heit durch atom are Massenvernichtungsmittel sollten die Kenntnisse strahlenbiologischer Grundlagen und Zusammenhange zum Wissen eines jeden Arztes und Biologen gehoren. In diesem Sinne wiinsche ich der Schrift meines Mitarbeiters Dr. Herrmann eine weite Verbreitung. Das Werk soll dazu beitragen, Grundfragen unseres Zeitalters wissenschaftlich begriindet beurteilen zu konnen und spezifische Probleme der Strahlentherapie und -diagno stik besser Zu verstehen. Dresden, im Dezember 1977 R. Barke Vorwort Die Strahlenbiologie mu ) als ein Grenzgebiet der Medizin bezeichnet werden. Diesc Feststellung schmalert jedoch die Bedeutung dieses Grundlagenfaches fur die Radiologie und fur viele weitere Teilgebiete der klinischen Medizin in keiner Weise. Sie verdeutlicht im Gegenteil die Tatsache, da ) strahlenbiologisches Wissen gemeinsam von Bio logen, Chemikern, Physikern und Medizinern zusammengetragen wurde."

This issue of MRI Clinics of North America focuses on The Gut in MRI: From the Upper to the Lower Digestive Tract, and is edited by Dr. Andrea Laghi. Articles will include: Esophagus and stomach: Is there a role for MRI?; MR of the small bowel: How to do it; MR in Crohn's Disease: Diagnosis, disease burden and classification; MR in Crohn's Disease: Imaging biomarkers in assessing response to therapy; MR of malabsorption syndromes, vasculitis, and other uncommon diseases; MR of small bowel tumors; MR enema of the colon in the diagnosis of recto-sigmoid endometriosis; Rectal cancer: Staging; Rectal cancer: Assessing response to neoadjuvant therapy; MR of anal and peri-anal tumors; MR of perianal fistulas; and more!

Alles S p e z i lis a ten tum bringt durch tiefes Eindringen in die Einzelheiten unzweifelhaften Nutzen fUr die Kranken und dieser ist nur durch die Arbeitsteilung zu erreichen. Daher muB seine Ausbreitung sHindig zunehmen. Nattirlich sind mit ihm, auch Nachteile verbunden: Ganz abgesehen von den Pseudo spezialisten ohne grtindliche Fachkenntnisse kann der Kran'ke auch schlecht fahren, wenn seine Behandlung ausschlieBlich in Handen von Spezialisten liegt. Wahrend der gut ausgebildete praktische Arzt im engen Kontakt mit der Familie wichtige, dem Kranken selbst unbekannte Einzelheiten und Untersuchungs ergebnisse weiB, wahrend er in diagnostisch zweifelhaften Fallen unvoreingenommen das eigene und die spezialistischen U rteile abwagt, wahrend der Hausarzt in therapeutischer Hinsicht die Konstitution, den Allgemeinzustand, die Lebensgewohnheiten, die psychische Einstellung des Kranken, Dinge, die in vielen Fallen wichtiger sind als das lokale Leiden, berticksichtigen k'ann, arbeitet der direkt vom Kranken aufgesuchte Spezialist ohne verifizierte Vorgeschichte, neigt in zweifelhaften Fallen zur Annahme einer Affektion aus seinem Bereiche, will und kann der Allgemeinbehandlung nicht Nachdruck verschaffeft und muB die Behamdlung beenden lassen, wenn der Patient aus irgendeinem Grunde fernbleibt, oft in bedenklichem Zu stand, bloB weil er gerade keine Beschwerden hat, oder weil sie langsamer weichen, als er erwartet."

Der Arzt, der bei Anwendung eines Medikamelltes dessen experimentelI erwiesene oder auch nur hypothetische pharma kodynamische Wirkung kennt, wird zielbewuEt die Indikation zur Anwendung dieses Medikamentes stelIen und ist aueh in del' Lage, die Wirkung des betreffenden Pharmakons im Einzelfall kritiseh zu beurteHen. Das gleiche gilt llaturgemiill ftir die physikaIisehen Heil ll1ethoden. Die physikalischen Heilmethoden wurden grofienteils zuerst von Laien angewendet und erst spiiter in die Schulmedizin aufgenommen. Anfangs hatten sie gegen eine gewisse Gering schiHzung seitens der Arzteschaft anzukampfen. Diese Gering schatzung wieh aber dann einer vielfaeh gedankenlosen polyprag matisehen Anwendung dieser Methoden. Es ist das Verdienst von Win t ern i t z, zunachst fUr die Hydrotherapie die wissenschaft lichen Grundlagen geschaffen zu haben; fUr eine ganze Reihe anderer physikalischer Heilmethoden, wie Elektrotherapie, Licht therapie und insbesondere Diathermie haben vielfach physiolo gisch experimentelle ArbeiteJ\ die Grundlage fUr die Benrteilung ihrer Wirksamkeit gegeben. Wenn in dieselll Btichlein tiber Warmetherapie, Hnd zwar tiber Diathermie und Heifiluftanwendung sowie liber die Anwell dung der ktinstliehen Hohensonne in der Lichttherapie gesprochen werden soll, so ist es nicht zu ulIlgehen, daE die physikalisehen und physiologischen Grundlagen dieser Heilmethoden in Klirze besprochen werden, da sieh aus diesen Erkenntnissen heraus die wiehtigsten Indikationen der Anwendung dieser Methoden oft von selbst ergeben. DaE sich wie bei allen anderen Heilmethoden auch bei den physikalischen zahlreiche nur rein empirisch gefun dene Heilwirkungen zeigen, darf uns nicht wundern."

This issue of PET Clinics focuses on PET Imaging in Pediatric Patients and is edited by Drs. Hongming Zhuang and Abass Alavi. Articles will include: Promising New PET tracers in the evaluation of pediatric disease; F-DOPA PET/CT in the management of congenital hyperinsulinism; Emerging roles of PET/MRI in pediatric hospital; Roles of FDG PET/CT in the management of posttransplant lymphoproliferative disease in pediatric patient; FDG-PET/CT in the management of pediatric lymphoma; Preparation and logistic consideration in performing PET/CT and PET/MRI in pediatric patients; PET/CT in the evaluation of FUO and infectious/inflammatory disease in pediatric patients; Roles of PET/CT in the evaluation of neuroblastoma; Potential Roles of Total Body Imaging in Pediatric Diseases and Disorders; PET/CT in the Management of Pediatric Sarcomas; Pediatric Cardiac PET Imaging; Dosimetry between PET/CT and PET/MRI: Implications in Pediatric Imaging; Essential Role of Global Disease Assessment in Assessing Systemic Disorders, and more!

This issue of Radiologic Clinics of North America focuses on Vascular Imaging, and is edited by Dr. Christopher J. Francois. Articles will include: Pre-operative planning for structural heart disease; Updates in vascular CT; Imaging patients with mesenteric ischemia; Imaging patients with pulmonary vascular disease; Peripheral vascular imaging focusing on non-atherosclerotic disease; Imaging thoracic aorta aneurysms; Recent innovations in renal vascular imaging; Radiological imaging in large and medium vessel vasculitis; MR lymphangiography; Recent innovations in vascular ultrasound; Imaging vascular malformations; 4D Flow MRI; and more!

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfangen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen fur die historische wie auch die disziplingeschichtliche Forschung zur Verfugung, die jeweils im historischen Kontext betrachtet werden mussen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.

This issue of MRI Clinics of North America focuses on MR Imaging of the Shoulder, and is edited by Drs. Naveen Subhas and Soterios Gyftopoulos. Articles will include: Shoulder MRI & MRA Techniques (New Advances): How I do it; Rotator Cuff Disease (New Concepts and Challenges): How do I read it; The Postoperative Rotator Cuff: How I read it; Anterior Instability: What to look for; Posterior Instability: What to look for; SLAP/biceps/thrower's shoulder: How I read it; Postoperative Labrum and Instability: What to look for; Capsular injury and inflammation: How I read it; AC Joint: What to look for; Nerve and muscle abnormalities: How I read it; Tumor/tumor like lesions: What to look for; Shoulder MRI and US: How do I choose; and more!

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfangen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen fur die historische wie auch die disziplingeschichtliche Forschung zur Verfugung, die jeweils im historischen Kontext betrachtet werden mussen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.

This issue of PET Clinics focuses on Evolving Role of PET in Interventional Radiology Based Procedures, and is edited by Drs. Abass Alavi (the Consulting Editor of PET Clinics), Marnix Lam, Stephen Hunt, and Ghassan El-Haddad. Articles will include: Y-90 PET/CT and radioembolization; FDG-PET and radioembolization; Ga-68-PSMA PET and HCC; C11 Acetate-PET for hepatocellular carcinoma patients undergoing radioembolization; FDG-PET for Ablation Treatment Planning, Intraprocedural Monitoring and Response; Global FDG Response Assessment to IR Procedures with Concomitant Immunotherapy; PET Assessment of Abscopal Effects and Pseudoprogression from IR Procedures; FDG-PET for monitoring response to embolotherapy (TACE) in primary and metastatic liver disease; and more!

External beam therapy is the most common form of radiotherapy, delivering ionizing radiation such as high-energy x-rays, gamma rays, or electron beams directly into the location of the patient's tumour. Now in its third edition, this book is an essential, practical guide to external beam radiotherapy planning and delivery, covering the rapid technological advances made in recent years. The initial chapters give a detailed insight into the fundamentals of clinical radiotherapy. This is followed by systematic details for each tumour site commonly treated with radiotherapy, covering indications, treatment, and planning. The final chapter covers the all important aspect of quality assurance in radiotherapy delivery. This third edition has been fully updated and revised to reflect new techniques, including details of intensity modulated radiotherapy (IMRT), image guided radiotherapy (IGRT), stereotactic body radiotherapy (SBRT), and proton therapy. Written by experts in each field, External Beam Therapy is an invaluable companion to professionals and trainees in medical physics, therapeutic radiology, and clinical or radiation oncology. ABOUT THE SERIES Radiotherapy remains the major non-surgical treatment modality for the management of malignant disease. It is based on the application of the principles of applied physics, radiobiology, and tumour biology to clinical practice. Each volume in the series takes the reader through the basic principles of the use of ionizing radiation and then develops this by individual sites. This series of practical handbooks is aimed at physicians both training and practising in radiotherapy, as well as medical physics, dosimetrists, radiographers, and senior nurses.

This issue of Neuroimaging Clinics of North America focuses on Temporal Bone Imaging: Clinicoradiologic and Surgical Considerations, and is edited by Drs. Gul Moonis and Amy Fan-Yee Juliano. Articles will include: Imaging of Temporal Bone Infection Inflammation; Imaging of Meniere's Disease; Treatment of Vestibular Schwannoma; Post Operative Imaging of the Temporal Bone; Otosclerosis and Dysplasias of the Temporal Bone; Imaging of Syndromes with Temporal Bone Abnormalities; Imaging of Third Window Lesions; Imaging of Tinnitus; Imaging of Temporal Bone Tumors; Imaging of Pediatric Hearing Loss; Common Otologic Surgical Procedures: Clinical Decision Making Pearls; Imaging of Temporal Bone Trauma: A Clinicoradiologic Perspective; and more!

This issue of Radiologic Clinics of North America focuses on Imaging of the Pelvis and Lower Extremity, and is edited by Drs. Laura Bancroft and Kurt Scherer. Articles will include: Turf toe injury/Plantar plate pathology; Lisfranc injury; Metatarsalgia; Ankle impingement types; Posterolateral corner injury; Imaging of the post-operative meniscus; Demystifying uncommon sources of pelvic pain; Current concepts of femoro-acetabular impingement; Bone/soft tissue tumors about the foot/ankle; Ultrasound intervention of the lower extremity/pelvis; Lower extremity neuropathies (entrapment); Extreme sport injuries of the pelvis/lower extremity; and more!

This book presents the most up-to-date and innovative information on the targeting and treatment of a wide range of childhood cancers by means of radiation therapy. Written by global experts in pediatric radiation oncology, it documents in detail the treatment regimens appropriate to each disease, highlighting the recent advances that promise to improve rates of survival and cure. The use of image-guided and intensity-modulated radiation therapy is clearly described, and careful attention is also devoted to the roles of proton therapy, stereotactic radiosurgery, stereotactic fractionated radiosurgery, and modulated arc radiotherapy. Separate chapters address localization and verification procedures and anesthesia; pediatric radiation oncology in the palliative care setting; and aspects that are especially relevant in low- and medium-income countries. Beyond clinical radiation oncology, relevant information is provided on radiation physics. The book concludes by examining future directions in the field.

Written and edited by internationally recognised leaders in the field, the new edition of the Oxford Textbook of Oncology has been fully revised and updated, taking into consideration the advancements in each of the major therapeutic areas, and representing the multidisciplinary management of cancer. Structured in six sections, the book provides an accessible scientific basis to the key topics of oncology, examining how cancer cells grow and function, as well as discussing the aetiology of cancer, and the general principles governing modern approaches to oncology treatment. The book examines the challenges presented by the treatment of cancer on a larger scale within population groups, and the importance of recognising and supporting the needs of individual patients, both during and after treatment. A series of disease-oriented, case-based chapters, ranging from acute leukaemia to colon cancer, highlight the various approaches available for managing the cancer patient, including the translational application of cancer science in order to personalise treatment. The advice imparted in these cases has relevance worldwide, and reflects a modern approach to cancer care. The Oxford Textbook of Oncology provides a comprehensive account of the multiple aspects of best practice in the discipline, making it an indispensable resource for oncologists of all grades and subspecialty interests.

This book provides a complete overview of the role of machine learning in radiation oncology and medical physics, covering basic theory, methods, and a variety of applications in medical physics and radiotherapy. An introductory section explains machine learning, reviews supervised and unsupervised learning methods, discusses performance evaluation, and summarizes potential applications in radiation oncology. Detailed individual sections are then devoted to the use of machine learning in quality assurance; computer-aided detection, including treatment planning and contouring; image-guided radiotherapy; respiratory motion management; and treatment response modeling and outcome prediction. The book will be invaluable for students and residents in medical physics and radiation oncology and will also appeal to more experienced practitioners and researchers and members of applied machine learning communities.

Proton beam therapy is an emerging technology with promise of revolutionizing the treatment of cancer. While nearly half of all patients diagnosed with cancer in the US receive radiation therapy, the majority is delivered via electron accelerators, where photons are used to irradiate cancerous tissue. Because of the physical properties of photon beams, photons may deposit energy along their entire path length through the body. On the other hand, a proton beam directed at a tumor travels in a straight trajectory towards its target, gives off most of its energy at a defined depth called the Bragg peak, and then stops. While photons often deposit more energy within the healthy tissues of the body than within the cancer itself, protons can deposit most of their cancer-killing energy within the area of the tumor. As a result, in the properly selected patients, proton beam therapy has the ability to improve cure rates by increasing the dose delivered to the tumor and simultaneously reduce side-effects by decreasing the dose to surrounding tissue. The benefits of proton beam therapy in delivering a lethal hit to the target while sparing surrounding normal tissues from radiation are becoming applicable to an increasing number of patients and a growing list of conditions. In this book, the author will guide the reader through existing evidence supporting proton beam therapy for pediatric cancer, prostate cancer, lung cancer, brain tumors, spinal tumors, and several other conditions. The book will discuss which conditions are suitable for treatment with proton beam therapy, how the treatment is delivered, and the current data supporting its use.

Lung cancer, which was rare at the beginning of the 20th century, is now a major cause of cancer-related deaths in men and women. It is the most frequently diagnosed cancer in the world. With conventional radiation therapy, small doses of radiation are delivered on a daily Monday-to-Friday schedule over a period of approximately a month and a half. After receiving this therapy, some reversible side effects, such as local skin irritation, are common. Robotic stereotactic radiotherapy is based on the principle of delivering high doses of radiation to the tumor while sparing or avoiding the surrounding tissues, which has been one of the greatest limiting factors of conventional radiation therapy historically. Given the advancements in technology, the reproducibility of patient positioning and the capability to deliver radiation from hundreds of different directions while synchronizing respiration-induced target motion, this technology is now proposed as a new local treatment, completed in less than one week, with promising results.

Interventional Oncology is a fast-growing new field, as well as an emerging specialty. Many minimally-invasive, imaging-guided procedures seem set to replace more traditional open surgical techniques of treating solid tumors in a variety of organs. The aim of this book is to describe new interventional radiological methods in a succinct and practical form. Diagnostic radiological considerations relevant to the selection and follow-up of patients are also covered. The book begins with an overview of the basic principles of current interventional techniques, including thermal ablation, high intensity focused ultrasound, and embolization. Later chapters focus on tumors of the liver, kidney, lung, and bone, placing new interventional techniques in context by referring to the surgical and oncologic methods of treating the same conditions. With an emphasis on best practices, Interventional Oncology: A Practical Guide for the Interventional Radiologist will serve as a definitive guide to practicing physicians involved in this rapidly evolving field.