As the dialysis population grows, an expert medical resource on the percutaneous creation and maintenance of vascular access is much needed. This book fulfills exactly that need, engaging interventional radiologists, vascular surgeons, interventional nephrologists, and the medical support personnel serving these patients. Providing a clear understanding of best techniques and practices, the authors present an unbiased discussion of patient preparation, procedures, and new devices and equipment. Logically organized and concluding with a compelling collection of 15 noteworthy cases, the book is the culminating work of leading experts in their specialties. The first truly practical reference dedicated to this topic, Essentials of Percutaneous Dialysis Interventions extends across multiple medical specialties to address a global health problem. Easy to use, reader-friendly, and portable, experienced practitioners and trainees alike will find this book to be of daily value.

Despite significant improvement in the management of patients with chronic kidney disease, the morbidity and mortality remain high. However more is now understood about the hormonal influence on bone and vascular structures, and there have been major advances in the field of bone and mineral metabolism. This has lead to the development of new treatment strategies and agents.
This new second edition reflects the most current thinking and understanding in this fascinating field, as presented by world basic and clinical experts.

The purpose of the book is to explain the current state of the art use of calcium antagonists in hypertension and, specifically, hypertensive and diabetic kidney disease. The authors offer an up to date insight in the changing world of calcium channel blockers. Furthermore, scientific research has improved drug designs with better pharmacodynamic profile that allows once daily administration and twenty four hours antihypertensive effects. These achievements on effectiveness have been accompanied by reduced effects when compared with classical calcium antagonists. Most interestingly, this book examines new calcium channel blockers, which may effect kidney microcirculation. A comprehensive review of experimental and clinical facts directed to both basic research and clinical practice is also given in this book.

Whether You Are A Newly Diagnosed Patient With Chronic Kidney Disease, Or Have A Friend Or Relative Undergoing Kidney Dialysis, This Book Offers Help. 100 Questions & Answers About Kidney Dialysis Gives Authoritative, Practical Answers To Your Questions About Kidney Dialysis, Including Preparation, Nutrition, Complications, And Maintaining A Healthy Lifestyle. Insider Tips And Advice Are Given From Both Physicians And Actual Patients Making This Book Is An Invaluable Resource For The 20 Million Americans Coping With The Physical And Emotional Turmoil Of This Disease.

The kidneys are responsible for many key bodily functions, but their primary role as a filter of toxins makes them extremely susceptible to disease. Often these diseases can only be diagnosed through a renal biopsy, a complicated procedure requiring ancillary immunologic and molecular diagnostic techniques. Many academic centers set aside dedicated laboratories specifically for renal pathology due to the amount of expertise required. This book covers all methods used by renal pathologists to diagnose a wide range of kidney diseases. Unlike most literature on renal pathology, this book is situated on the midpoint between encyclopedic and superficial coverage, written for the signing-out pathologist. While focusing on tumors and transplantation rejection, a full spectrum of infectious, inflammatory, and congenital disorders is covered in both pediatric and adult populations and is analyzed not only by light microscopy but by each applicable diagnostic modality available. The text is illustrated with more than 1,000 photomicrographs and diagrams, including a CD-ROM of all images.

The described material is very important for the clinical and scientific transplantation, because it shows that the atrophy and functional depression of the transplanted kidney is caused not only by immune rejection, but also by non-specific factors of transplantation(denervation, warm ischemia). By means of evidence based reliable data the book confirms the necessity of an artificial surgical re-innervation and relevant hypothermia support of a transplanted kidney which ensures its full value and long-time function.

In the present book the authors introduce the utilisation of FNs in the concept of Magnetically Assisted Hemodialysis (MAHD) for the treatment of End Stage Renal Disease (ESRD). ESRD patients have to be subjected to permanent Hemodialysis (HD) therapy having a typical schedule of three 4-hour sessions per week. The proposed strategy of MAHD aims to become a more efficient development of conventional HD. The core of the idea is the production of Ferromagnetic Nanoparticles-Targeted Binding Substance Conjugates (FN-TBS Cs) constructed of biocompatible FNs and a specifically designed TBS. The TBS part is necessarily used for increasing the biocompatibility of the FNs host carriers, but most importantly should have high affinity and binding capacity for the specific Target Toxic Substance (TTS) that should be removed from the patient. For these demands to be fulfilled, antibodies or even specific proteins could serve as the TBS part of the desired FN-TBS Cs. The FN-TBS Cs should be administered to the patient timely prior to the MAHD session so that, owing to their free circulation in the vascular network, they will be able to collect the desired TTSs through their adsorption onto the TBS part of the Cs. However, long residence times of the FN-TBS Cs in the blood stream cannot be used so that noticeable triggering of the reticuloendothelial system to be avoided. As a result, the binding dynamics of the FN-TBS Cs with candidate TTSs are of major importance. Eventually, the complex FN-TBS-TTS can be selectively removed during the MAHD session by means of a "magnetic dialyser", that is an external magnetic field applied either at the conventional dialyser or at other point(s) along the extracorporeal blood circulation line of the dialysis machine. The advantages of MAHD over conventional HD are discussed in detail among issues of practical importance. Some of the main advantages are the following: (i) Increased rate of toxin removal, (ii) Selective targeting of specific TTSs and prevention by the respective disorders during early stages, (iii) Decreased duration of each dialysis session, and (iv) Adjustment of the blood flow rate to relatively lower values. Apart from these primary benefits related to the comfort and overall health status of the patient, enormous financial benefits will also evolve for National Health Budgets despite the fact that the proposed MAHD strategy requires small investments for the only modest modification of existing dialysis machines. The authors hope that the utilisation of MAHD into clinical practice will become a reality in the near future so that long-term-HD patients will benefit from all the advantages discussed here, and from many more that will probably evolve after intense {in vivo} applications are completed.

Kidney transplantation has revolutionised the treatment of end-stage renal failure. Not only does it offer the best hope for complete rehabilitation, but it has also proved to be the most cost-effective of all treatment options, including dialysis. The surgical techniques involved have been mastered for half a century and are now considered routine. Nevertheless, this should not prevent us from appreciating the range and complexity of the issues surrounding kidney transplantation. This book examines the latest research in this field including rejection.

The increasing number of small renal tumours being detected had led to the recent development of nephron-sparing surgery. Cryotherapy has become an important treatment option for renal tumours. The recent advances in cryosurgery have occurred as a result of the recent of the introduction of open-type MRI. This new and important book details research on perutaneous freezing therapy by means of MR image monitoring for hepatic carcinomas, renal carcinomas and uterine fibroids. The therapy allows minimising damage to the tissue around the frozen area.

Book initiates with introductory material to hemodialysis technology and its historical evolution and later on divulging into the field of biomaterials. With this background, the book discusses selection criteria of a suitable biomaterial for synthesis of haemodialysis membranes along with illustration of a complete indigenous, low cost technology for spinning of haemodialysis fibres. Well illustrated description of instruments used for membrane characterization and biomedical engineering is also provided at suitable junctures to effectively present the concept including worked out examples. Present title can be a good textbook as well as a research material for membrane as well as biomedical engineering curricula and provides coverage for appropriate undergraduate and graduate students interested in hemodialysis membranes.

Kidney Disease: From advanced disease to bereavement provides guidance to renal and palliative care professionals dealing with patients with advanced kidney disease, who are approaching end of life. The book describes the tools used to achieve a good death including advance care planning, symptom control law and ethics, recognizing dying, withdrawal of treatment, and a holistic approach to patient care. By using case histories, the book highlights how to facilitate good communication between patients, families and their renal and palliative teams. There are also chapters on support for carers and bereavement. Revised and updated, this new edition is written in a bullet point style to provide an indispensable guide to the day-to-day management of patient care. This pocketbook will be an essential guide for nephrologists, renal nurses, nephrologist trainees, and doctors and nurses working in palliative care.

This book provides an evidence based guide to the management of common kidney conditions. Concise and highly structured chapters outline a diagnosis and treatment framework for kidney diseases encountered within daily practice. Particular attention is given to the management of chronic kidney disease, genetic kidney diseases, cardiovascular complications, haemodialysis, kidney cancer, peritoneal dialysis, and kidney transplantation. Management of Kidney Disease aims to improve outcomes for patients with kidney diseases and is relevant to trainee and practising nephrologists, as well as healthcare professional treating kidney diseases. Additional questions and answers via app: Download the Springer Nature Flashcards app free of charge and use exclusive additional material to test your knowledge.

This book provides healthcare professionals in Critical Care setting an easy consultation guide to fight against COVID-19. The book is divided into sections: Fundamentals of COVID-19, Pneumological critical care, Neurological manifestations, Cardiovascular manifestations, Renal manifestations, Haemostasis and coagulation, Other multi-organs involvement, Principles of therapy. Each section includes: * brief pathophysiology of COVID-19 (ventilation, neurological, cardiovascular, etc.); * principles of management (enriched with flowcharts and figures); * principles of therapy; * tips and key messages. Readers can find the most updated advices on how to face the ongoing pandemic: from principles of conventional oxygen therapy, assisted and invasive mechanical ventilation in critically ill COVID-19 patients to the complications sometimes underestimated. Tables and flowcharts provided are based on current knowledge in COVID-19 to help the clinician managing COVID-19 patients by a multiple-organs prospective. Written by international key opinion leaders of each field, the book represents a point of reference for all professionals involved in the management of COVID-19 pandemic.

This book will cover all aspects of hypertension and the manifestations of cardiovascular disease in the Asian population. Asia has the largest population of all the continents, and also has the largest number of people suffering from these diseases. Due to an expanding economy and increasing affluent lifestyles, their incidence is increasing at alarming rates - in fact, this continent is a ticking time bomb for HTN and CVD outbreaks. The book fills a large gap, as there are currently no volumes on this topic - and provides much-needed information for physicians not only in Asia but globally. Not only physicians, but also all related medical professionals and libraries will benefit from this book, to which renowned international experts contributed.

This book provides comprehensive, cutting-edge scientific data on acute and chronic tubulointerstitial nephritis, an area that has not been fully addressed in many nephrology textbooks. This book covers all relevant aspects of the disease, from historical aspects and pathogenesis to diagnosis, pathological findings, treatment, and prognosis and outcomes. The chapters also discuss both immune and non-immune mediated forms of the disease, as well as entities causing tubulointerstitial disease such as medications and toxins, infectious agents, autoimmune diseases, transplant rejection, genetic diseases, infiltrative disease and chronic kidney disease of unknown etiology. The text features up-to-date educational materials that will benefit both basic and clinical scientists. Written by experts in the field, Tubulointerstitial Nephritis is a valuable resource for clinicians, practitioners, researchers and trainees working in the field of nephrology and internal medicine.

The second edition of this educational book provides an updated resource on how best to discuss and manage acute and chronic presentations of renal diseases. All chapters have been reviewed and updated to reflect changes which directly affect clinical practice and new chapters have been added including Dialysis and Poisoning, Urinalysis/Microscopy and Renal Biopsy. Chapters now include information on key clinical trials for management strategies Allowing for concise reading on specific topics this book acts as both a quick reference text and study guide. The layout has been designed in a question and answer format in order to promote self-directed learning. Images and diagrams have been further standardized and improved for the new edition and remain a key feature of the book.Clinical Companion in Nephrology, second edition, is an invaluable resource for junior doctors, medical students and renal nurses who encounter renal patients in their daily practice.

This book covers all key aspects of critical care in pediatric nephrology, including acute dialysis in sick children. It also provides detailed protocols for managing fluid and electrolyte balance and dialysis in children in intensive care. In addition, this quick guide discusses innovations in pediatric renal replacement therapy technologies, such as plasma exchange, CARPEDIEM, NIDUS and aquadex. This is a go-to book for intensivists, physicians and trainees working in pediatric intensive care units.

Edited by the same team that developed the successful Pediatric Dialysis and its second edition, this text features clinical management principles that are integral to the care of children receiving chronic dialysis. Each chapter is introduced by a case presentation that serves as the basis for key learning points that are clinically applicable and presented in a succinct manner. The topics included in Pediatric Dialysis Case Studies cover virtually all aspects of pediatric dialysis care and represent the efforts of an international group of experts with firsthand clinical expertise from all disciplines represented in the pediatric dialysis team. This resource is certain to help the clinician achieve improved outcomes for these often complex patients.

Dieses Buch bietet neuen Kollegen und Wiedereinsteigern im Fachbereich Dialyse Unterstutzung bei der schnellen Einarbeitung in den neuen Bereich oder auf der neuen Station. Motto: "Keine Angst vor einem Stationswechsel" Es bietet ein schnelles Nachschlagen in konkreten Situationen und Platz fur wichtige Notizen. Checklisten helfen tagliche Ablaufe (Visiten, UEbergaben, Monitoring) und Vorgange (Bestellungen) zu optimieren.

This book bridges the gap between advances in basic biology and chemistry and technological applications in the field of toxicity assessments. It describes areas of progress in the laboratory and clinic and discusses aspects of cellular organelles. It also covers the basic principles and applications of modern toxicological tools such as transcriptomic, proteomic, and metabolomic approaches. The recent developments on molecular modeling and systems biology are described with an eye on the future establishment of virtual cell technology. Finally the clinical implications for the understanding of acute and chronic renal toxicity are studied.

This reference work provides a comprehensive review of the most crucial and provocative aspects of pancreas transplantation. It represents a unique source of information and guidance for the current generation of transplant surgeons that evolved from being pure clinicians into savvy administrators knowledgeable in every regulatory aspect governing transplantation. The book contains 15 chapters covering every single aspect of the surgical operation in the donors as well as the recipients of pancreas transplants. The pre-operative workup, as well as the post-operative immunosuppression management, and the treatment of recurrent diseases are addressed in detail. In addition, the book further expands the role of islet cell transplant with its ever increasing prominence, which includes the role of autologous islet cell transplant. The impact of increasing regulatory burdens from the federal government coupled with the economic and health burden of Diabetes mellitus is discussed.

Das Handbuch Angiologie 2010 enthalt die Manuskripte zum Seminar Angiologie Update 2010. Diese berucksichtigen die wesentlichen angiologischen Publikationen der internationalen Literatur des Jahres. Dem Update-Konzept entsprechend sichten die renommierten Autoren die Literatur in den zentralen Kernbereichen der Angiologie, stellen die wichtigsten Ergebnisse vor und kommentieren diese bezuglich ihrer Praxisrelevanz. Somit gibt das Handbuch Angiologie 2010 einen kompakten und aktuellen Uberblick uber die wichtigsten Themen der Angiologie.

Minimally Invasive Therapy for Urinary Incontinence and Pelvic Organ Prolapse provides a detailed insight into "when, why, what and how" of various minimally invasive surgical procedures for surgical management of SUI, OAB & POP. The volume provides detailed diagrammatic /pictorial step by step descriptions of the techniques and management of complications related to these procedures. This book presents an up to date, one-stop reference for anything pertaining to MIT of these pelvic disorders. Minimally Invasive Therapy for Urinary Incontinence and Pelvic Organ Prolapse is designed for both the urologist and urogynecologist treating patients with urinary disorders and pelvic organ prolapse as well as for residents in training.

RICHARD J. GLASSOCK Introducing a scientific symposium is an uncertain and difficult task. The remarks must not be too specific lest the participant's later contributions be intruded upon, yet an overview of the goals and objectives of the conference should be presented in an inquisitive and stimulating fashion. Perhaps a compromise position would be to make a few general statements and pose a limited number of questions which hopefully would then be addressed dur­ ing the formal or informal portions of the meeting. A conclusion incorpo­ of the relevance of the specific topic to the more rating some perspectives global issues of disease and its consequences might be appropriate. The goals and objectives of this conference, as set forth by its organizers, Professors Ponti celli, D'Amico and Minetti, are rather simple and straight­ forward; namely, to review and elucidate the immunopathophysiology of cryoimmunoglobulins and auto-antibodies to immunoglobulins (lg) and, secondarily, to explore the possible participation of these disordered states in glomerular injury. As such, this conference is principally devoted to an analysis of two properties of certain species of the globulin fraction of serum proteins, specifically the ability to self associate on the basis of immune interactions and to form insoluble aggregates when exposed to reduced ambient temperature. As we shall see, these two properties are often dis­ tinctly related.