In this book, the authors present topical research in the study of the indications, procedures and complications of hemodialysis. Topics discussed in this compilation include cardiovascular involvement in chronic kidney disease; nutritional therapy during hemodialysis; vascular access and common complications in patients undergoing hemodialysis treatment; prevention of hemodialysis catheter-related infections; antiplatelet medication and the risk of bleeding in hemodialysis; and vascular calcifications in end stage renal disease.

Pathology of the Kidney in Dysproteinemia is an academic monograph describing in detail the causes and development of structural and functional changes in the human kidney resulting from the deposition of abnormal circulating serum proteins. The material presented was obtained from 147 cases of renal involvement associated with Dysproteinemia encountered in university and community hospital settings. The described entities account for 4.5% of 3.260 biopsies of native kidneys examined over a period of approximately 25 years. While some of the lesions are quite rare, others are relatively common and seen fairly frequently in a reasonably busy renal biopsy service. Together they constitute a group of extremely interesting lesions in terms of immunology, morphology, and pathogenesis.This book should be of interest to pathologists- especially renal pathologists, immunologists, and internists. Both general internists and sub-specialists in nephrology and hematology will find this volume useful, as will medical residents and medical technologists in these various specialties. As a monograph it is user-friendly, since the subject matter is sufficiently circumscribed to permit expanded or detailed visual and textual treatment of specific lesions in a single easy-to-wield volume.

The discovery of a potent vasoconstrictor, endothelin (ET)-1, derived from vascular endothelial cells was among a variety of key lines of investigation that helped to fuel a major explosion of studies related to endothelial cell biology. This was particularly evident within the pharmaceutical industry where receptor antagonists were quickly developed and are now on the market for treatment of pulmonary hypertension and in development for other diseases such as diabetic nephropathy and cancer. Importantly, we know that the kidney contains the highest level of ET-1 production and receptor expression in the body where it has been demonstrated to function as a pro-natriuretic autocrine and paracrine factor that is activated in conditions of high salt intake. This eBook provides a review of the various mechanisms whereby ET-1 has been shown to function within the kidney through a wide range of actions that include direct effects on tubular transport, intrarenal hemodynamics, as well as neural and endocrine functions. Much has yet to be discerned, but it is clear that the ET system is a major physiological regulator of fluid-electrolyte balance and blood pressure through these renal actions. Table of Contents: Discovery of Endothelin / Basic Biology of the Endothelin System / Renal Localization / Renal Hemodynamics / Renal Tubular Actions of Endothelin / Endothelin in Neural Modulation of Renal Function / Physiological Role of Endothelin / Endothelin in Renal Pathology / References / Author Biographies

In 1989, the nephrology community was confronted with the combination of high tech and high flux, realising for the first time that short, but mathematically "adequate" therapy resulted in unacceptable outcomes. This book discusses issues that doctors must pay close attention to; those that cause the greatest harm to patients. New discoveries prove that chronic kidney disease (CKD) causes a muscle wasting syndrome, and that epo hyporesponsiveness harbingers a variety of underlying etiologies. From renowned surgeons, doctors are gaining practical insights into methods to improve arteriovenous fistula survival and cardiovascular surgery outcomes. The book applies the new information that can now be accessed to meet the personal needs of these patients.

Heme oxygenases (HOs) are the enzymes responsible for the breakdown of heme and the generation of biliverdin/bilirubin and carbon monoxide (CO). The kidney is a complex organ consisting of many different cell types all working together for the single purpose of filtering the blood to eliminate waste products and conserving ions, minerals, and water necessary for life. HO enzymes and their products play a critical role in the normal function of the kidney as well as protecting the kidney from various insults including ischemia and exposure to nephrotoxins. For example, the HO metabolite, bilirubin, is a potent antioxidant which can limit damage to renal tubular epithelial cells following exposure to nephrotoxins associated with chemotherapy or traumatic injury. Another HO metabolite, CO, is an important vasodilator of renal blood vessels and helps protect against severe decreases in renal blood flow in conditions as diverse as exposure to radiocontrast agents and in hypertension-induced kidney disease. HO and its metabolites also play an important role in the survival of kidney cells after acute and chronic injuries by regulating important cell growth and programmed cell death pathways. The intent of this volume is to highlight the important role that HO enzymes and their related metabolites, bilirubin and CO, play in the regulation of renal function and in the response of the kidney to both acute and chronic pathologies. Table of Contents: Introduction to the HO System / HO and Renal Vascular Function / HO and Renal Tubule Function / HO and Acute Kidney Injury / HO and Chronic Kidney Injury / Future of Renal HO Research / References

Little Black Book Of Nephrology And Hypertension Is A Comprehensive Pocket Reference To All Aspects Of Kidney Disease. This Convenient Resource Offers Quick Access To Vital Information And Makes A Great Reference For Solving Pressing Problems On The Ward Or In The Clinic.

Every Year, High Blood Pressure Causes More Than 25,000 New Cases Of Kidney Failure In The United States. 100 Questions & Answers About Kidney Disease And Hypertension Offers Authoritative, Up-To-Date, Practical Answers About Kidney Disease, End-Stage Kidney Failure, Transplants, And Dialysis. The Book Is An Invaluable Resource For Anyone Coping With The Physical And Emotional Turmoil Of This Condition.

In this era of evidence-based medicine, one of the biggest challenges confronting clinicians is keeping abreast with often rapidly changing recommendations that guide clinical practice. While it is clearly helpful to have research-based guidelines and protocols to draw upon, it is not always easy to access this information particularly at the time when it is needed most, such as on a ward round or in a busy outpatient clinic. These evidence-based guidelines, produced by national organisations (The Renal Association, British Hypertension Society, National Institute for Health and Clinical Excellence) and international organisations (International Society of Nephrology, National Kidney Federation- KDOQI) are often found in a variety of locations and published media and therefore timely access is not always possible.
This desk reference is designed to overcome this problem. The editors have produced a comprehensive summary of nephrology which focuses on aspects of renal disease that are important to the clinician, and have brought together the key recommendations found in current evidence-based guidelines and presented them in a uniform and accessible format. It has been designed and written so that locating information is both quick and simple, and the layout of the chapters allows the reader to identify and assimilate information rapidly.

This manual contains protocols and guidance documents assembled by the authors during many years of clinical experience in nephrology. Many are not evidence-based but we have found them useful and hope that others will do likewise. The recommendations were made on the basis of clinical trials wherever possible. In the absence of relevant clinical trials, we used evidence available or our personal experience. Our aim was to provide a manual for the treatment of the most frequent kidney diseases or disorders related to the practice of Nephrology. The information may be of use to nephrologists, general internists, general practitioners or medical students.

This scarce antiquarian book is included in our special Legacy Reprint Series. In the interest of creating a more extensive selection of rare historical book reprints, we have chosen to reproduce this title even though it may possibly have occasional imperfections such as missing and blurred pages, missing text, poor pictures, markings, dark backgrounds and other reproduction issues beyond our control. Because this work is culturally important, we have made it available as a part of our commitment to protecting, preserving and promoting the world's literature.

This story depicts the love of two soul mates and the miracle of life that was given: a kidney. She knows a "higher power" allows unbelievable things to happen. Their lives together survive the good times and slow times of prosperity, to the diagnosis of kidney failure. From the blue days of his dialysis treatments to the day after surgery, their lives are a true inspiration to those who love "Dialysis Patience" and hope for a donor.

Eisenstoffwechselstorungen, insbesondere der Eisenmangel, zahlen zu den am haufigsten ubersehenen oder fehlgedeuteten Erkrankungen. Anamien sind ein weltweites Problem. Davon betroffen sind vor allem altere Menschen. Nach den WHO-Kriterien (World Health Organisation. Nutritional anemias. Technical Reports Series 1992; 503) spricht eine Hb-Konzentration

Why do we sleep? How much sleep do we really need? What causes sleep apnea, narcolepsy, and insomnia-and what can be done about these sleep disorders? Why do older people have more trouble sleeping than young people? We have all puzzled over-or been plagued by-the mysteries of sleep. Now a leading researcher on sleep provides an engaging and informative introduction to the subject that answers many of our questions. Peretz Lavie surveys the entire field of sleep research and sleep medicine-from the structure of sleep stages and the brain centers involved in sleep regulation to the reasons for and significance of dreams, the importance of sleep in maintaining good health, and the function of biological rhythms-interweaving facts with fascinating case histories, anecdotes, and personal reflections. We learn, for example, about: *development of sleep patterns from infancy to adulthood and in the aged; *the wide variety of sleep habits in animals; *dreams of Holocaust survivors; *sleep under the threat of Scud missile attacks; *how melatonin influences sleep; *the story of the "Acrobat's Leap" sleep-deprivation experiments in the Israeli army; *how to treat insomnia; *what to do with a baby who refuses to go to sleep; and much more. Originally published in Hebrew to great acclaim, this book will enlighten and entertain everyone interested in how and why we sleep.

This superb new resource serves as a stepwise companion for the laparoscopic urologic surgeon, guiding all skill levels to the state of the art in this innovative and challenging specialty. It provides detailed instructions on everything from the beginner's basics and the tools of the trade, to the most advanced procedures being practised today, with an emphasis on safety and on avoiding complications. Over 210 outstanding photographs and line drawings help make each point clear and easy to follow. Features: * Guides readers through all the necessary instrumentation and the best operating suite setup, as well as key features of tools such as video systems, cameras, laparascopic lenses, dissection instruments and more. * Provides information on anatomic, physiologic, and anaesthetic considerations, laparoscopic entry and exit, less involved procedures such as varicocelectomy and pelvic lumphadenectomy and other important basics. * Covers the full range of advanced procedures, such as laparoscopic kidney, ureter, adrenal, bladder and retroperitoneal surgery, including suturing and stapling techniques.

For nearly 50 years, Sleisenger & Fordtran's Gastrointestinal and Liver Disease has been the go-to reference for gastroenterology and hepatology residents, fellows, physicians, and the entire GI caregiving team. Now in a fully revised 11th Edition, this two-volume masterwork brings together the knowledge and expertise of hundreds of global experts who keep you up to date with the newest techniques, technologies, and treatments for every clinical challenge you face in gastroenterology and hepatology. A logical organization, more than 1,100 full-color illustrations, and easy-to-use algorithms ensure that you'll quickly and easily find the information you need. Features new and expanded discussions of chronic hepatitis B and C, Helicobacter pylori infection, colorectal cancer prevention through screening and surveillance, biologic agents and novel small molecules to treat and prevent recurrences of inflammatory bowel disease (IBD), gastrointestinal immune and autoimmune diseases, and more. Offers reliable coverage of key topics such as Barrett's esophagus, gut microbiome, enteric microbiota and probiotics, fecal microbiota transplantation, and hepatic, pancreatic, and small bowel transplantation. Provides more quick-reference algorithms that summarize clinical decision making and practical approaches to patient management. Employs a consistent, templated, format throughout for quick retrieval of information. Includes monthly updates online, as well as more than 20 procedural videos. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

The third edition of a bestseller, this book provides insight from a wide array of international contributors in the field of pediatric nephrology. Copiously illustrated with photomicrographs and clinical diagrams, the third edition reflects current advances in the field. Each chapter contains a set of questions, directed at helping fellows succeed at the American Pediatric Nephrology Board examination. New information for this edition includes changes in treatment options for hyponatremia, and updates on hyperparathyroidism and transplantation. Text boxes highlight important "take home points" throughout the chapters. Clinical Pediatric Nephrology, Third Edition will be a valuable reference for clinicians in nephrology, pediatrics and urology, and any professional involved in the care of children with renal diseases seeking a reliable contemporary text.

Kidney transplantation is a medical procedure performed on patients with end-stage kidney disease that can increase their life expectancy by several years. However, the procedure involves some risk and potential complications. Chapter One of this monograph summarizes the current strategy for diagnosis and treatment of chronic kidney disease-associated mineral bone disease (CKD-MBD) in kidney transplant recipients and aims to demonstrate the latest findings and therapeutic options in the field beyond recent published guidelines. Chapter Two describes the necessity of involving a psychiatrist in the transplant team to facilitate positive outcomes in kidney transplants, as psychological factors can contribute to treatment non-compliance and other issues. Chapter Three defines the surgical techniques used in living donor nephrectomy, discusses the use and reliability of these techniques in different patient groups, and examines the long-term follow-up results of donors and recipients. Lastly, Chapter Four discusses the variables involved in treating patients with autosomal dominant polycystic kidney disease (ADPCKD), whose enlarged and deformed kidneys can complicate kidney transplantation.

This handbook on vacuolar and plasma membrane H+-ATPases is the first to focus on an essential link between vacuolar H+-ATPase and the glycolysis metabolic pathway to understand the mechanism of diabetes and the metabolism of cancer cells. It presents recent findings on the structure and function of vacuolar H+-ATPase in glucose promoting assembly and signaling, in addition to describing the regulatory mechanisms of vacuolar H+-ATPase in yeast cells, neural stem cells, kidney cells, cancer cells, as well as under diabetic conditions.

This book provides a concise yet comprehensive overview of acid-base disorders. Each chapter reviews an acid-base disorder, covering pathophysiology, evaluation, and management of the disorder. The chapters also include clinical cases and a Q&A section, based on scenarios and questions that clinicians regularly encounter when treating patients with these disorders. The book concludes with two chapters on acid-based disorders in special patient populations, including critically ill patients, pregnant patients, and surgical patients. Written by an expert in the field, Acid-Base Disorders: Clinical Evaluation and Management is a state-of-the-art resource that should assist clinicians and practitioners in managing patients with acid-base disorders.

Das Grundlagenwerk fur Dialyse-Teams

Fur die professionelle Versorgung von Dialysepatienten und Nierenkranken finden Pflegende und medizinische Fachangestellte hier alles Wissenswerte rund um das Gebiet der Nephrologie und Dialyse, u. a.: pflegerische Aufgabenbereiche akuter und chronischer Nierenerkrankungen Ernahrungsempfehlungen bei Dialysepflicht Planung und Organisation der Arbeitsablaufe in Dialyseeinrichtungen Nierentransplantation.

Verstandlich geschrieben, mit zahlreichen Abbildungen, Tabellen und Merksatzen erganzt, eignet sich das Werk hervorragend zum Lernen und Nachschlagen.

• Alle Inhalte der Fachweiterbildung Nephrologie und Dialyse
• Stellenbeschreibungen fur Fachpersonal in der Nephrologie und Dialyse
• Glossar wichtiger Fachbegriffe

Empfohlen von der Deutschen Gesellschaft fur Fachkrankenpflege und Funktionsdienste."

Uric acid (UA) is an end-product of purine derivatives in human metabolism. Without further metabolism, it is excreted by kidneys and intestinal tract. Its serum concentration is controlled by the balance between production and excretion. High concentration of UA in human body has been discovered to be associated with various diseases, such as gout, hyperuricaemia, Lesch-Nyan disease, obesity, diabetes, high cholesterol, hypertension, kidney disease and heart disease. This book discusses the detection, applications and role in health and disease of uric acid.

Diabetic Nephropathy (DN) is the leading cause to end-stage renal disease all over the world. Unfortunately, no effective treatment is available to stop its progression. So far, many key issues remain unrevealed in relation to its pathogenesis, new forms of therapy, and complication intervention. In this book, the authors aim to provide updated medical knowledge and practical management strategies to medical professionals who are caring for DN patients based on their ample clinical experiences, strong bench and bedside research background, and tight collaboration with experts in other fields caring for common complications in DN. The authors also want to shed light on the work of bench researchers in fields of DN and its complications from a clinical perspective.

This practical book covers the basic principles and practice of dialysis access management, a crucial part of the care of patients undergoing hemodialysis. It has been written in an easy-to-read, step-by-step format to help facilitate learning and understanding of the procedures and has been supplemented with numerous operative photographs and diagrams demonstrating the commonly performed dialysis access exams, interventions, procedures and surgeries. Dialysis access management is an essential text for residents, fellows and physicians who are learning or practicing in dialysis and/or dialysis access management, especially in the fields of nephrology, radiology, surgery and vascular medicine.

This book has been complied by a group of doctors and nurses from all the over the world. The editors of this book aim to ensure that the reader gets the different perspective of how haematuria is managed all over the world. Chapter contributions have been received from the UK, USA, Spain, India, Japan, Albania, Singapore and Sri Lanka. From a patient's perspective, finding blood in the urine can be a very frightening experience and must be investigated. This book helps provides an update on the common Aetiologies and Management of both adult and paediatric patients. In the book there are contributions from both Nephrologists and Urologists discussing the details of both visible and non-visible haematuria which will help guide the reader with the best management strategies for these groups of patients. Also presented in this book are chapters which purely focus on the patient's perspective of haematuria.

Creatinine, a muscle waste product, is widely interpreted as a measure of renal function. However, the serum level reflects not only renal excretion, but also the generation, intake, and metabolism of creatinine. In this book, the authors present current research in the study of the production, diagnostic uses and role in renal disease of creatinine. Topics include the diagnostic use of creatinine in pre-eclampsia; serum creatinine and its effect and management in renal and hepatic disease; evaluation of renal function in patients with cirrhosis; the role of creatinine in kidney disease in neonates, infants and children; and retinol X creatinine in kidney disease.