Membranes in Pulmonary Vascular Disease, Volume 82, the latest release in the Current Topics in Membranes series, highlights new advances in the field, with this new volume presenting interesting chapters from recognized experts on topics such as Sphingolipids in Vascular Lung Disease, Endothelial Glycocalyx, Cholesterol Regulation of Endothelial Cell Calcium Homeostasis in Pulmonary Hypertension, Mechanosensitive Channels and Gap Junction Channels in EC, Endothelial Protrusions in Junctional Integrity and Barrier Function, Cortical Actin Dynamics in Endothelial Permeability, Endothelial Microparticles and Exosomes, Store Operated TRP Channels and Endothelial Responses, and Caveolin and Endothelial NO signaling.

Advances in Catalysis, Volume 62, fills the gap between journal papers and textbooks across a diverse areas of catalysis research. For more than 60 years, this series has recorded and presented the latest progress in the field of catalysis, providing the scientific community with comprehensive and authoritative reviews. This series is an invaluable and comprehensive resource for chemical engineers and chemists working in the field of catalysis in both academia and industry.

Darwin's Pangenesis and Its Rediscovery Part A highlights the findings of Darwin's Pangenesis, an expanded cell theory and unified theory of heredity and variation that strengthened his theory of evolution and explained many phenomena of life. Now, new advances and the discovery of circulating cell-free DNA, mobile RNAs, prions and extracellular vesicles are providing new breakthroughs, thus increasing evidence on the inheritance of acquired characters, graft hybridization, and many other phenomena that Pangenesis suggests. Sections of note in this volume include the rationale, criticisms, influence and recent molecular evidence of Darwin's Pangenesis, as well as its relation to the inheritance of acquired characters, which is often included under the blanket term "transgenerational epigenetic inheritance."

Dehydroepiandrosterone, Volume 108, the latest release in the Vitamins and Hormones series first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics such as Dehydroepiandrosterone Research: Past, Current and Future, Astrocyte Neuroprotection and Dehydroepiandrosterone, Mutation of HSD3B2 Gene and Fate of Dehydroepiandrosterone, Autophagy and Autophagic Cell Death: Uncovering New Mechanisms Whereby Dehydroepiandrosterone Promotes Beneficial Effects on Human Health, Dehydroepiandrosterone and Cardiovascular Disease, Dehydroepiandrosterone and Experimental Osteoarthritis, The Role of Dehydroepiandrosterone (DHEA) in Skeletal Muscle, Mechanism of Action of Dehydroepiandrosterone, and more.

Advances in Marine Biology, Volume 79, the latest release in a series that has been providing in-depth and up-to-date reviews on all aspects of marine biology since 1963, updates on many topics that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology and biological oceanography. This latest release includes a review of patterns of multiple paternity across sea turtle rookeries, parasites and pathogens in seabirds, progress in marine genomics and bioinformatics, the rise of sea turtle research and conservation, and the potential impacts of offshore oil and gas activities on deep-sea sponges and the habitats they form.

An informal and highly accessible writing style, a simple treatment of mathematics, and clear guide to applications have made this book a classic text in electrical and electronic engineering. The fundamental ideas relevant to the understanding of the electrical properties of materials are emphasized; in addition, topics are selected in order to explain the operation of devices having applications (or possible future applications) in engineering. The mathematics, kept deliberately to a minimum, is well within the grasp of undergraduate students. This is achieved by choosing the simplest model that can display the essential properties of a phenomenom, and then examining the difference between the ideal and the actual behaviour. The whole text is designed as an undergraduate course. However most individual sections are self contained and can be used as background reading in graduate courses, and for interested persons who want to explore advances in microelectronics, lasers, nanotechnology, and several other topics that impinge on modern life.

Characterizing the Alteration of Ovoproducts Using New Analytical Approaches focuses on the capabilities (potential or proven) of the latest metabolomics based analytical approaches for the (early) diagnostic of the alteration of ovoproducts during their production/preservation processes. It details the ovoproduct matrix, their known sources of biotic and abiotic alteration, and their associated biomarkers. In addition, the book covers the capabilities (exploratory and characterization) of the latest metabolomics tecnics, both invasive and non-invasive, including chromatography, nuclear magnetic resonance, mass spectrometry, NMR, MS - including FTICR-MS -, and vibrational spectroscopy, such as Infrared - MIR, NIR - or Raman). In final sections, the next generation of online sensors derived from the latest technics is discussed for their applicative potential in industry (NIR, Raman, chromatography, benchmark NMR, and more).

High-Density Sequencing Applications in Microbial Molecular Genetics, Volume 612 in the Methods of Enzymology series provides the latest on the high-density sequencing of DNA and cDNA libraries and how they have revolutionized contemporary research in biology. Methods permitting tens of millions of sequence reads in a single experiment have paved the way to genome-wide studies that are contributing to our understanding of the complexity of living systems. Chapters in this updated volume include Characterizing the role of exoribonucleases in the control of microbial gene expression: Differential RNA seq., Conformational studies of bacterial chromosomes by high-throughput sequencing methods, Measuring mRNA degradation, and more. Addition sections cover Global recognition patterns of bacterial RNA-binding proteins, High-resolution profiling of NMD targets, and the Generation of a metagenomic 3C/Hi-C library of human gut microbiota, Genome-wide mapping of yeast retrotransposons integration target sites, Measuring protein synthesis rates, Finding unsuspected partners of small RNAs with new screening approaches, Use of multiplexed transcriptomics to define the relationship between promoter sequence and transcription output, RNA-based control of quorum sensing in Vibrio cholerae, amongst other highly regarded topics.

Data Analysis for Omic Sciences: Methods and Applications, Volume 82, shows how these types of challenging datasets can be analyzed. Examples of applications in real environmental, clinical and food analysis cases help readers disseminate these approaches. Chapters of note include an Introduction to Data Analysis Relevance in the Omics Era, Omics Experimental Design and Data Acquisition, Microarrays Data, Analysis of High-Throughput RNA Sequencing Data, Analysis of High-Throughput DNA Bisulfite Sequencing Data, Data Quality Assessment in Untargeted LC-MS Metabolomic, Data Normalization and Scaling, Metabolomics Data Preprocessing, and more.

Integrated Population Biology and Modeling: Part A offers very complex and precise realities of quantifying modern and traditional methods of understanding populations and population dynamics. Chapters cover emerging topics of note, including Longevity dynamics, Modeling human-environment interactions, Survival Probabilities from 5-Year Cumulative Life Table Survival Ratios (Tx+5/Tx): Some Innovative Methodological Investigations, Cell migration Models, Evolutionary Dynamics of Cancer Cells, an Integrated approach for modeling of coastal lagoons: A case for Chilka Lake, India, Population and metapopulation dynamics, Mortality analysis: measures and models, Stationary Population Models, Are there biological and social limits to human longevity?, Probability models in biology, Stochastic Models in Population Biology, and more.

Enzymes Conjugated to Graphene, Volume 609 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on Enzyme immobilization, Detection of Urea, Enzyme immobilization Enzyme immobilization, PAMAM dendrimer modified reduced graphene oxide post functionalized by horseradish peroxidase for biosensing H2O2, HRP immobilized for LEV detection, Enzyme immobilization, Graphene biocatalysts, Enzyme immobilization, Interactions, Enzyme immobilization, GQD, Enzyme Immobilization, and Enzyme immobilization on functionalized graphene oxide nanosheets.

Cell Volume Regulation and Fluid Secretion, Volume 81, the latest release in the Current Topics in Membranes series highlights new advances in the field, with this new volume presenting interesting chapters on General principles of cell volume regulation, Cell volume maintenance: water and salt homeostasis, The search for ubiquitous cell volume sensor: the role of plasma membrane and cytoplasmic hydrogel, More than membranes, Cellular and membrane biomechanics of CVR response, Molecular identities of volume-regulatory anion channels, Molecular biology and physiology of volume-regulated anion channel (VRAC), the Role of WNKs in the modulation of intracellular chloride, amongst other topics.

Advances in Agronomy continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied, and exemplary of the abundant subject matter addressed by this long-running serial.

Handbook of Magnetic Materials, Volume 27, covers the expansion of magnetism over the last few decades and its applications in research, notably the magnetism of several classes of novel materials that share the presence of magnetic moments with truly ferromagnetic materials. The book is an ideal reference for scientists active in magnetism research, providing readers with novel trends and achievements in magnetism. Each article contains an extensive description given in graphical, as well as, tabular form, with much emphasis placed on the discussion of the experimental material within the framework of physics, chemistry and materials science.

Can one correlate the philosophical musings of one of the most famous football coaches in history with the best ACS Student Member Chapters? Yes! The link is in the excellence. Award-winning Student Member Chapters-several leaders of which have been kind enough to write a chapter in this volume-all have caught excellence in one or more facets of what they do. Mio and Benvenuto began this journey to capture the best of Student Member Chapters back in 2015, when they asked some of the best and most active organizations' leadership to put into words what they did that puts them at the top. The editors realized there is not one, specific answer to such questions, but found a wealth of information in what their chapter authors reported. There are more voices in this wonderful chorus, voices of leaders who have great ideas and who have figured out ways to make the fascination of chemistry communicable to our students and the general public. This volume represents some excellent input as to what makes a chapter award-winning, and what keeps its excellence sustainable.

Advances in Rice Research for Abiotic Stress Tolerance provides an important guide to recognizing, assessing and addressing the broad range of environmental factors that can inhibit rice yield. As a staple food for nearly half of the world's population, and in light of projected population growth, improving and increasing rice yield is imperative. This book presents current research on abiotic stresses including extreme temperature variance, drought, hypoxia, salinity, heavy metal, nutrient deficiency and toxicity stresses. Going further, it identifies a variety of approaches to alleviate the damaging effects and improving the stress tolerance of rice. Advances in Rice Research for Abiotic Stress Tolerance provides an important reference for those ensuring optimal yields from this globally important food crop.

Genetic Models and Molecular Pathways Underlying Autism Spectrum Disorders, Volume 241 provides the most recent information on the animal model systems that are available to study different forms of autism spectrum disorders. In addition to genetically engineered animals that uniquely model genetic forms of ASD, this volume also provides detailed chapters on a variety of specific topics, including An overview of genetic models of ASDs, Phenotypic modeling of ASD symptoms, Molecular mechanisms of NF1 model of ASD symptoms, Ube3a gene dosage disorders: molecular and circuit mechanisms of ASD, Circuit dysfunctions in ASD models, ERK signaling in genetic models of ASD, and more.

Imaging in Movement Disorders: Imaging in Atypical Parkinsonism and Familial Movement Disorders, Volume 142, addresses the use of imaging modalities across the spectrum of movement disorders and dementias. Over the last decades, advances in neuroimaging tools have played a pivotal role in expanding our understanding of disease aetiology and pathophysiology, identifying biomarkers to monitor disease progression, aiding differential diagnosis and in the identification of novel targets for therapeutic intervention. This updated volume covers PET Molecular Imaging in Atypical Parkinsonism, SPECT Molecular Imaging in Atypical Parkinsonism, Structural MRI in Atypical Parkinsonism, Functional MRI in Atypical Parkinsonism, and more.

Studies in Natural Products Chemistry, Volume 59, the latest in the series, covers the synthesis, or testing and recording, of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, this book is a welcomed resource.

Darwin's Pangenesis and its Rediscovery Part B explores Darwin's Pangenesis, an expanded cell theory and unified theory of heredity and variation from over 150 years ago that strengthened his theory of evolution and explained many phenomena of life. Now, new discoveries on circulating DNA, mobile RNAs, prions and extracellular vesicles are providing striking evidence for the chemical existence of Darwin's imaginary gemmules. In addition, new evidence for the inheritance of acquired characters, graft hybridization, and many other phenomena that Pangenesis supposedly explains are progressing, and are hence explored in this comprehensive volume. Specific chapters in this new volume include Darwin and Mendel: The Historical Connection, Darwin's Pangenesis and Graft Hybridization, Darwin's Pangenesis and Medical Genetics, Darwin's Pangenesis and Certain Anomalous Phenomena, and Natural Selection and Pangenesis: The Darwinian Synthesis.

New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Genes Biochemistry and Applications consolidates the most widely used genetic methods available, bringing together the fields of biochemistry, biotechnology, and microbiology. The chapters outlined give clear and concise direction on both standard and applied microbial genetic improvements, presenting undergraduates, postgraduates, and researchers with the latest developments in microbial gene technology. In addition, the book describes the background and usefulness of each experiment in question. All chapters covered in the book are derived from current peer-reviewed literature as accepted by the international scientific community.

Stochastic Analysis of Mixed Fractional Gaussian Processes presents the main tools necessary to characterize Gaussian processes. The book focuses on the particular case of the linear combination of independent fractional and sub-fractional Brownian motions with different Hurst indices. Stochastic integration with respect to these processes is considered, as is the study of the existence and uniqueness of solutions of related SDE's. Applications in finance and statistics are also explored, with each chapter supplying a number of exercises to illustrate key concepts.

The Opioid System as the Brain's Interface between Cognition and Motivation, Volume 239, focuses on the opioid system as the interface between the brain's cognitive and motivational systems. As the opioid system is widely distributed through the brain, particularly in areas implicated in cognition (hippocampus, prefrontal cortex, claustrum, thalamus) and motivation (hypothalamus, amygdala, pontine nuclei, periaqueductal gray and medulla), this book provides chapters that address ongoing research on topics such as the Brain's cognitive system, the Brain's motivational system, Antidepressant prescription patterns, Antidepressant-like effects of opioid receptor modulators, the Behavioral effects of antidepressant and anxiolytic drugs, and more.

Cerebral Lateralization and Cognition: Evolutionary and Developmental Investigations of Motor Biases, Volume 238, the latest release in the Progress in Brain Research series, discusses interdisciplinary research on the influence of cerebral lateralization on cognition within an evolutionary framework. Chapters of note in this release include Evolutionary Perspectives: Visual/Motor Biases and Cognition, Manual laterality and cognition through evolution: An archeological perspective, Laterality in insects, Motor asymmetries in fish, amphibians and reptiles, Visual biases and social cognition in animals, Mother and offspring lateralized social interaction across animal species, Manual bias, personality and cognition in common marmosets and other primates, and more.

Annual Reports in Computational Chemistry, Volume 14, provides timely and critical reviews of important topics in computational chemistry. Topics covered in this series include quantum chemistry, molecular mechanics, force fields, chemical education, and applications in academic and industrial settings. Focusing on the most recent literature and advances in the field, each article covers a specific topic of importance to computational chemists.