The role of the Maillard reaction in forming flavors from amino acid and sugar precursors has been studied for many years. To establish the basic chemistry of the reaction, researchers have used model systems, often solutions of a single amino acid with a single sugar. Despite the apparent simplicity of the system, heating such a solution can generate tens if not hundreds of compounds, which requires careful and time-consuming analysis to identify and quantify each component.
Data from the model systems has allowed researchers to study the pathways that lead to flavor formation, and various schemes have been proposed to identify the main "routes" that lead to flavor compounds. Such schemes have led to one of the main control principles, namely an understanding of the role of amino acids in forming some characteristic aromas, e.g., bread flavor from proline, as well as an appreciation of the role of C5 and C6 sugars in controlling the rate of reaction.
Recently, the formation of taste compounds through the Maillard reaction has been investigated and new potent compounds have been discovered that can contribute to the overall flavor formed during the Maillard reaction. These findings also offer the potential for control and manipulation of the Maillard reaction to form specific types of flavor. Although the nature of the end-products of the Maillard reaction in both food and model systems are well documented, applying these principles to control flavor formation in real foods has proved difficult.
This book describes recent research and developments related to the control of the Maillard reaction to give optimum flavor quality. These include kinetic modeling of the reaction, the effect of physical parameters (temperature, time, moisture content, pH), and the effect of chemical parameters (amino acid and sugar composition, the presence of other components). The topics covered relate to real food systems and reaction product flavorings, as well as model systems. Contributors from academia and industry have come together to provide an up to date overview of progress in this important area of flavor research.

Science and its philosophical companion, Naturalism, represent reality in wholly nonpersonal terms. How, if at all, can a nonpersonal scheme accommodate the first-person perspective that we all enjoy? In this volume, Lynne Rudder Baker explores that question by considering both reductive and eliminative approaches to the first-person perspective. After finding both approaches wanting, she mounts an original constructive argument to show that a nonCartesian first-person perspective belongs in the basic inventory of what exists. That is, the world that contains us persons is irreducibly personal. After arguing for the irreducibilty and ineliminability of the first-person perspective, Baker develops a theory of this perspective. The first-person perspective has two stages, rudimentary and robust. Human infants and nonhuman animals with consciousness and intentionality have rudimentary first-person perspectives. In learning a language, a person acquires a robust first-person perspective: the capacity to conceive of oneself as oneself, in the first person. By developing an account of personal identity, Baker argues that her theory is coherent, and she shows various ways in which first-person perspectives contribute to reality.

This third volume of NMR Spectroscopy in the Undergraduate Curriculum continues the work we started with the first and second volumes in providing effective approaches for using nuclear magnetic resonance spectrometers as powerful tools for investigating a wide variety of phenomena at the undergraduate level. This volume focuses on upper-level courses and NMR spectroscopy across the curriculum. The applications and strategies in this volume will be helpful to those who are looking to transform their curriculum by integrating more NMR spectroscopy, to those who might not have considered NMR spectroscopy as a tool for solving certain types of problems, or for those seeking funding for a new or replacement NMR spectrometer.

Quantum optics, i.e. the interaction of individual photons with matter, began with the discoveries of Planck and Einstein, but in recent years, it has expanded beyond pure physics to become an important driving force for technological innovation. This book serves the broader readership growing out of this development by starting with an elementary description of the underlying physics and then building up a more advanced treatment. The reader is led from the quantum theory of the simple harmonic oscillator to the application of entangled states to quantum information processing.
An equally important feature of the text is a strong emphasis on experimental methods. Primary photon detection, heterodyne and homodyne techniques, spontaneous down-conversion, and quantum tomography are discussed, together with important experiments. These experimental and theoretical considerations come together in the chapters describing quantum cryptography, quantum communications, and quantum computing.

This book is dedicated to Professor Leonid V Keldysh. His brilliant contributions to condensed matter physics include the Franz-Keldysh effect, an electron-hole liquid, the nonequilibrium (Keldysh) diagram technique, Bose-Einstein condensation (of excitons) and a metal-dielectric'' transition, acoustically-induced superlattices, multi-photon transitions and impact ionization in solids. In many respects, his work influenced and formed the paradigm of modern condensed matter physics. As a result, many famous researchers in the field have enthusiastically provided unique contributions to the book.

A series of seminal technological revolutions has led to a new generation of electronic devices miniaturized to such tiny scales where the strange laws of quantum physics come into play. There is no doubt that, unlike scientists and engineers of the past, technology leaders of the future will have to rely on quantum mechanics in their everyday work. This makes teaching and learning the subject of paramount importance for further progress. Mastering quantum physics is a very non-trivial task and its deep understanding can only be achieved through working out real-life problems and examples. It is notoriously difficult to come up with new quantum-mechanical problems that would be solvable with a pencil and paper, and within a finite amount of time. This book remarkably presents some 700+ original problems in quantum mechanics together with detailed solutions covering nearly 1000 pages on all aspects of quantum science. The material is largely new to the English-speaking audience. The problems have been collected over about 60 years, first by the lead author, the late Prof. Victor Galitski, Sr. Over the years, new problems were added and the material polished by Prof. Boris Karnakov. Finally, Prof. Victor Galitski, Jr., has extended the material with new problems particularly relevant to modern science.

The logician Kurt Goedel in 1951 established a disjunctive thesis about the scope and limits of mathematical knowledge: either the mathematical mind is not equivalent to a Turing machine (i.e., a computer), or there are absolutely undecidable mathematical problems. In the second half of the twentieth century, attempts have been made to arrive at a stronger conclusion. In particular, arguments have been produced by the philosopher J.R. Lucas and by the physicist and mathematician Roger Penrose that intend to show that the mathematical mind is more powerful than any computer. These arguments, and counterarguments to them, have not convinced the logical and philosophical community. The reason for this is an insufficiency if rigour in the debate. The contributions in this volume move the debate forward by formulating rigorous frameworks and formally spelling out and evaluating arguments that bear on Goedel's disjunction in these frameworks. The contributions in this volume have been written by world leading experts in the field.

How far should our realism extend? For many years philosophers of mathematics and philosophers of ethics have worked independently to address the question of how best to understand the entities apparently referred to by mathematical and ethical talk. But the similarities between their endeavours are not often emphasised. This book provides that emphasis. In particular, it focuses on two types of argumentative strategies that have been deployed in both areas. The first-debunking arguments-aims to put pressure on realism by emphasising the seeming redundancy of mathematical or moral entities when it comes to explaining our judgements. In the moral realm this challenge has been made by Gilbert Harman and Sharon Street; in the mathematical realm it is known as the 'Benacerraf-Field' problem. The second strategy-indispensability arguments-aims to provide support for realism by emphasising the seeming intellectual indispensability of mathematical or moral entities, for example when constructing good explanatory theories. This strategy is associated with Quine and Putnam in mathematics and with Nicholas Sturgeon and David Enoch in ethics. Explanation in Ethics and Mathematics addresses these issues through an explicitly comparative methodology which we call the 'companions in illumination' approach. By considering how argumentative strategies in the philosophy of mathematics might apply to the philosophy of ethics, and vice versa, the papers collected here break new ground in both areas. For good measure, two further companions for illumination are also broached: the philosophy of chance and the philosophy of religion. Collectively, these comparisons light up new questions, arguments, and problems of interest to scholars interested in realism in any area.

This book is aimed at students making the transition from a first course on general relativity to a specialized subfield. It presents a variety of topics under the general headings of gravitational waves in vacuo and in a cosmological setting, equations of motion, and black holes, all having a clear physical relevance and a strong emphasis on space-time geometry. Each chapter could be used as a basis for an early postgraduate project for those who are exploring avenues into research in general relativity and who have already accumulated the required technical knowledge. The presentation of each chapter is research monograph style, rather than text book style, in order to impress on interested students the need to present their research in a clear and concise format. Students with advanced preparation in general relativity theory might find a treasure trove here.

The authors of this book argue that there is a great divide between species that makes extrapolation of biochemical research from one group to another utterly invalid. In their previous book, "Sacred Cows and Golden Geese: The Human Cost of Experiments on Animals", the Greeks showed how an amorphous but insidious network of drug manufacturers, researchers dependent on government grants to earn their living, even cage-manufacurers - among others benefiting from "white-coat welfare" - have perpetuated animal research in spite of its total unpredictability when applied to humans. (Cancer in mice, for example, has long been cured. Chimps live long and relatively healthy lives with AIDS. There is no animal form of Alzheimer's disease.) In doing so, the Greeks aimed to blow the lid off the "specious science" we have been culturally conditioned to accept. Taking these revelations one step further, this book uses accessible language to provide the scientific underpinning for the Greeks' philosophy of "do no harm to any animal, human or not," by examining paediatrics, diseases of the brain, new surgical techniques, in vitro research, the Human Genome and Proteome Projects, an array of scien

A combination of population growth, public health failures, environmental degradation and rapid global transportation has resulted in a world that is at increasing risk to vectorborne and other infectious diseases. A large percentage of emerging diseases are vectorborne and over one-third of the agents on the list of greatest concern from bioterrorism are vectorborne. Many of these diseases are viral that have no effective drug or vaccine treatments. Drug and insecticide resistance is now common and has greatly compromised our ability to provide effective and affordable control. Parasitic diseases, including malaria, leishmmaniasis and African trypanosomiasis are likewise increasing in many parts of the world. Control programs for onchocerciasis and to some extent filariasis are reducing the impact of these diseases, largely due to the availability of filaricides such as ivermectin. Chagas disease has also declined significantly through home improvements and indoor insecticide application against the domicilary kissing bug vectors.
Despite these gains, this tend has not been sustainable. Instead, infectious disease is now responsible for greater than 25% of all deaths and nearly 50% of premature deaths among those under 45 years of age, and 63% for children less than 4 years of age. A significant proportion of these deaths is attributed to vectorborne diseases, particularly from malaria ( 11%). Indeed, more that 1 million people are killed annually by malaria, about 3000 per day. It is estimated that 700,000 children under the age of 5 die of malaria and at least 300 million are ill due to malaria each year. In response, the American Institute of Medicine (2003) has called for a renewed effort to rebuild public health infrastructures needed to conduct disease surveillance and vector control programs and to increase research to provide improved pesticides and their use, new repellents, new biopestcides and biocontrol agents to augment pesticidal control, as well as novel strategies to interrupt pathogen transmission.
With these goals in mind, we convened the first vector control symposium as part of the scientific program of the 3rd Pan-Pacific Conference of Pesticide Science in 2003. Five years after (2008), we re-convened this expanded topic at the 4th Pan-Pacific Conference on Pesticide Science and the scientific presentations made over two days comprise this current volume, Advances in Human Vector Control. The book covers two major areas: 1) Current Status and Control Practices, covering malaria, dengue, Chagas, human lice, cockroach and house dust mite issues; and 2) Novel Approaches and Resistance Management of these diseases. Chapters are provided by internationally-recognized experts who are actively involved in vector control and management, providing an up to date summary of this critically important area of public health. The effective use of novel control strategies is stressed and the status of recently acquired genomic approaches is critically reviewed.

The powerful potential of digital media to engage citizens in political actions has now crossed our news screens many times. But scholarly focus has tended to be on "networked," anti-institutional forms of collective action, to the neglect of advocacy and service organizations. This book investigates the changing fortunes of the citizen-civil society relationship by exploring how social changes and innovations in communication technology are transforming the information expectations and preferences of many citizens, especially young citizens. In doing so, it is the first work to bring together theories of civic identity change with research on civic organizations. Specifically, it argues that a shift in "information styles" may help to explain the disjuncture felt by many young people when it comes to institutional participation and politics. The book theorizes two paradigms of information style: a dutiful style, which was rooted in the society, communication system and citizen norms of the modern era, and an actualizing style, which constitutes the set of information practices and expectations of the young citizens of late modernity for whom interactive digital media are the norm. Hypothesizing that civil society institutions have difficulty adapting to the norms and practices of the actualizing information style, two empirical studies apply the dutiful/actualizing framework to innovative content analyses of organizations' online communications-on their websites, and through Facebook. Results demonstrate that with intriguing exceptions, most major civil society organizations use digital media more in line with dutiful information norms than actualizing ones: they tend to broadcast strategic messages to an audience of receivers, rather than encouraging participation or exchange among an active set of participants. The book concludes with a discussion of the tensions inherent in bureaucratic organizations trying to adapt to an actualizing information style, and recommendations for how they may more successfully do so.

Origins of Language: A Slim Guide offers a concise and accessible overview of what is known about the evolution of the human capacity for language. Non-human animals communicate in simple ways: they may be able to form simple concepts, to feel some limited empathy for others, to cooperate to some extent, and to engage in mind-reading. Human language, however, is characterized by its ability to efficiently express a wide range of subtle and complex meanings. After the first simple beginnings, human language underwent an explosion of complexity, leading to the very complicated systems of grammar and pronunciation found in modern languages. Jim Hurford looks at the very varied aspects of this evolution, covering human prehistory; the relation between instinct and learning; biology and culture; trust, altruism, and cooperation; animal thought; human and non-human vocal anatomy; the meanings and forms of the first words; and the growth of complex systems of grammar and pronunciation. Written by an internationally recognized expert in the field, it draws on a number of disciplines besides linguistics, including philosophy, neuroscience, genetics, and animal behaviour, and will appeal to a wide range of readers interested in language origins and evolution.

Transnational Cooperation: An Issue-Based Approach presents an analysis of transnational cooperation or collective action that stresses basic concepts and intuition. Throughout the book, authors Clint Peinhardt and Todd Sandler identify factors that facilitate and/or inhibit such cooperation. The first four chapters lay the analytical foundations for the book, while the next nine chapters apply the analysis to a host of exigencies and topics of great import. The authors use elementary game theory as a tool for illustrating the ideas put forth in the text. Game theory reminds us that rational actors (for example, countries, firms, or individuals) must account for the responses by other rational actors. The book assumes no prior knowledge of game theory; all game-theoretic concepts and analyses are explained in detail to the reader. Peinhardt and Sandler also employ paired comparisons in illustrating the book's concepts. The book is rich in applications and covers a wide range of topics, including superbugs, civil wars, money laundering, financial crises, drug trafficking, terrorism, global health concerns, international trade liberalization, acid rain, leadership, sovereignty, and many others. Students, researchers, and policymakers alike have much to gain from Transnational Cooperation. It is a crossover book for economics, political science, and public policy.

This volume is an attempt to educate, to provide a source of information, knowledge, and wisdom to the person who has spent so much time and energy on his or her schooling. The Council for Chemical Research (CCR) and the American Chemical Society (ACS) have both spent considerable effort over the past decades focusing on how to ensure that graduate education in the chemical sciences remains at the absolute highest caliber, and produces the best possible professionals. In spite of notable efforts from both organizations to prepare graduate students for the professional world, neither has specifically asked what a person needs to be successful once they have both the Ph.D. and the first job in hand. Put succinctly, there is much more to being successful in a career in chemistry than just the hard-earned Ph.D. degree. What You Need for the First Job, Besides the Ph.D. in Chemistry is based on a symposium of the same name held at the 246th National Meeting of the American Chemical Society, which took place in Indianapolis, Indiana in September, 2013. This book is the result of seeds that were planted during numerous informal conversations at the annual meetings of the CCR, as well as during such discussions at national and regional meetings of the ACS, and at the ACS employment clearing houses. The authors felt that the same intense focus a person needs to earn a Ph.D. might actually work against the attention to other details needed in order to be successful once he or she has obtained a position. Leaders want to ensure that new hires are working effectively toward tenure, are quickly becoming productive members of their corporate team, or are well integrated into their government laboratory research group. While it is easy to lump factors other than technical competence in one's job under the term "soft skills," this is an oversimplification. This book represents an attempt to have voices from all three pillars of the chemical enterprise - academia, industry, and government laboratories - heard in terms of relating what is important for their newly hired Ph.D.-holders. What You Need for the First Job, Besides the Ph.D. in Chemistry will be a valuable resource for first-time job seekers, as well as those with aspirations of a future career in the chemical sciences.

Developed for the new International A Level specification, these new resources are specifically designed for international students, with a strong focus on progression, recognition and transferable skills, allowing learning in a local context to a global standard. Recognised by universities worldwide and fully comparable to UK reformed GCE A levels. Supports a modular approach, in line with the specification. Appropriate international content puts learning in a real-world context, to a global standard, making it engaging and relevant for all learners. Reviewed by a language specialist to ensure materials are written in a clear and accessible style. The embedded transferable skills, needed for progression to higher education and employment, are signposted so students understand what skills they are developing and therefore go on to use these skills more effectively in the future. Exam practice provides opportunities to assess understanding and progress, so students can make the best progress they can.

Viruses that infect plants are responsible for reduction in both yield and quality of crops around the world, and thus are of great economic importance. This has provided the impetus for the extensive research into the molecular and cellular biology of these pathogens and into their interaction with their plant hosts and their vectors. However, interest in plant viruses extends beyond their ability to damage crops. Many plant viruses - for example, tobacco mosaic virus - have been used as model systems to provide basic understanding of how viruses express genes and replicate. Others permitted the elucidation of the processes underlying RNA silencing, now recognized as a core epigenetic mechanism underpinning numerous areas of biology. This book attests to the huge diversity of research in plant molecular virology. Written by world authorities in the field, the book opens with two chapters on the translation and replication of viral RNA. Following chapters cover topics such as viral movement within and between plants, plant responses to viral infection, antiviral control measures, virus evolution, and newly emerging plant viruses. The book concludes with two chapters on biotechnological applications of plant viruses. Throughout, the focus is on the most recent, cutting-edge research, making this book essential reading for everyone working with plant viruses.

Developed for the new International A Level specification, these new resources are specifically designed for international students, with a strong focus on progression, recognition and transferable skills, allowing learning in a local context to a global standard. Recognised by universities worldwide and fully comparable to UK reformed GCE A levels. Supports a modular approach, in line with the specification. Appropriate international content puts learning in a real-world context, to a global standard, making it engaging and relevant for all learners. Reviewed by a language specialist to ensure materials are written in a clear and accessible style. The embedded transferable skills, needed for progression to higher education and employment, are signposted so students understand what skills they are developing and therefore go on to use these skills more effectively in the future. Exam practice provides opportunities to assess understanding and progress, so students can make the best progress they can.

This ACS Symposium Series is the product of a symposium held at the 241st National Meeting of the American Chemical Society in Anaheim, CA on March 27-31, 2011. It includes chapters on new biobased building blocks such as the furandicarboxylic acid, polyesters and polyamides from adipic, succinic and sebacic acids with aliphatic diols such as 1,3-propylene glycol, 1,4-butanediol, 1,12-dodecylenediol and isosorbide. The conversion of hydroxymethylfurfural, the dehydration product of hexose sugars, to succinic acid and 1,4-butanediol to produce poly(butylene succinate) is described in one chapter. Also the synthesis of new polymers from plant-derived olefinic monomers such as tulipalin A and studies of composites from cotton by-products are featured in other chapters. There is a strong emphasis on biocatalytic synthesis and polymerization within the book. Chapter topics include the synthesis of ?-hydroxyfatty acids and polymers therefrom, an interesting discussion on the structural differences of the products of the biocatalytic and chemical catalytic synthesis of polyesters from oleic diacid and glycerol and the ability to produce polylactic acid (PLA) and PLA-PHA copolyesters within a "microbial cell factory". Other areas of interest explored in other chapters include recent developments of biobased polymer fibers and oleate-based pressure sensitive adhesives and composites. One chapter describes a large increase in cold-drawn fiber tensile strength by the blending of a small amount of ultrahigh molecular weight (MW) poly(3-hydroxybutyrate) with a much lower MW 3-hydroxybutyrate polymer. The addition of a rubber and inorganic fillers to normally brittle PLA was found to dramatically improve its ductility. Finally, there are several chapters on seed oil-based polyurethanes, one on fibers from soy proteins and composites from starch.

Through four editions, Lactic Acid Bacteria: Microbiological and Functional Aspects, has provided readers with information on the how's and why's lactic acid-producing fermentation improves the storability, palatability, and nutritive value of perishable foods. Thoroughly updated and fully revised, with 12 new chapters, the Fifth Edition covers regulatory aspects globally, new findings on health effects, properties and stability of LAB as well as production of target specific LAB. The new edition also addresses the technological use of LAB in various fermentations of food, feed and beverage, and their safety considerations. It features the detailed description of the main genera of LAB as well as such novel bacteria as fructophilic LAB and novel probiotics and discusses such new targets as cognitive function, metabolic health, respiratory health and probiotics. Key Features: In 12 new chapters, findings are presented on health effects, properties and stability of LAB as well as production of target specific LAB Covers such novel bacteria as fructophilic LAB and novel probiotics Presents new discoveries related to the mechanisms of lactic acid bacterial metabolism and function Covers the benefits of LAB, both in fermentation of dairy, cereal, meat, vegetable and silage, and their health benefits on humans and animals Discusses the less-known role of LAB as food spoilers Covers the global regulatory framework related to safety and efficacy

This book will explore our forests as the most readily available and renewable source of carbon as well as the building block of chemicals, plastics, and pharmaceuticals as the next 100 years gradually push consumers toward alternate sources of chemicals. Meeting these needs from trees requires that new chemistry be developed so that plant materials is converted to commodity chemicals. This focused discussion on ongoing global efforts at creativity using forest and biomass based renewable materials will include six different mechanisms for bringing about change on this very innovative topic.

The emergence of Shaken Baby Syndrome (SBS) presents an object lesson in the dangers that lie at the intersection of science and criminal law. As often occurs in the context of scientific knowledge, understandings of SBS have evolved. We now know that the diagnostic triad alone does not prove beyond a reasonable doubt that an infant was abused, or that the last person with the baby was responsible for the babys condition. Nevertheless, our legal system has failed to absorb this new consensus. As a result, innocent parents and caregivers remain incarcerated and, perhaps more perplexingly, triad-only prosecutions continue even to this day. Flawed Convictions: Shaken Baby Syndrome and the Inertia of Injustice is the first book to survey the scientific, cultural, and legal history of Shaken Baby Syndrome from inception to formal dissolution. It exposes extraordinary failings in the criminal justice systems treatment of what is, in essence, a medical diagnosis of murder. The story of SBS highlights fundamental inadequacies in the legal response to science dependent prosecution. A proposed restructuring of the law contends with the uncertainty of scientific knowledge.

Recent years have seen the rise of a remarkable partnership between the social and computational sciences on the phenomena of emotions. Rallying around the term Affective Computing, this research can be seen as revival of the cognitive science revolution, albeit garbed in the cloak of affect, rather than cognition. Traditional cognitive science research, to the extent it considered emotion at all, cases it as at best a heuristic but more commonly a harmful bias to cognition. More recent scholarship in the social sciences has upended this view.
Increasingly, emotions are viewed as a form of information processing that serves a functional role in human cognition and social interactions. Emotions shape social motives and communicate important information to social partners. When communicating face-to-face, people can rapidly detect nonverbal affective cues, make inferences about the other party's mental state, and respond in ways that co-construct an emotional trajectory between participants. Recent advances in biometrics and artificial intelligence are allowing computer systems to engage in this nonverbal dance, on the one hand opening a wealth of possibilities for human-machine systems, and on the other, creating powerful new tools for behavioral science research.
Social Emotions in Nature and Artifact reports on the state-of-the-art in both social science theory and computational methods, and illustrates how these two fields, together, can both facilitate practical computer/robotic applications and illuminate human social processes.